alkaplorer's classification system is hierarchically structured into five progressive levels (L1-L5) based on the innovative "Biogenetic-Structural" taxonomy.
Level 1 (L1): alkaloids are categorized into three primary classes: True Alkaloids (amino acid-derived with nitrogen embedded in heterocyclic rings), Protoalkaloids (amino acid-originated with exocyclic nitrogen), and Pseudoalkaloids (non-amino acid precursors).
Level 2 (L2): delves into specific biogenetic pathways, exemplified by classifications like L-ornithine-derived Alkaloids that trace nitrogenous compounds to their metabolic origins.
Level 3 (L3): identifying core ring systems such as Imidazole Alkaloids characterized by their distinct heterocyclic frameworks.
Levels 4,5 (L4, L5): L4 categorizes subtypes like Monoterpenoid Indole Alkaloids within broader groups, while L5 further distinguishes these into specific frameworks including Corynanthe-type alkaloids. This tiered system enables precise compound navigation while maintaining biosynthetic context, with continuous expansion planned to incorporate emerging phytochemical discoveries and enhance classification granularity.