Enzyme:

Enzyme Properties

EntryP45353 Entry NameHIS2_PICPA
Protein NamesHistidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19); Phosphoribosyl-ATP pyrophosphohydrolase (EC 3.6.1.31); Histidinol dehydrogenase (HDH) (EC 1.1.1.23)]
Gene NamesHIS4 OrganismKomagataella pastoris (Yeast) (Pichia pastoris)
EC NumbersEC 3.5.4.19; EC 3.6.1.31; EC 1.1.1.23 Enzyme TypeHydrolases
Length842.0 aa Reviewed Reviewed
From SourceP45353

Associated Reactions

Reaction ID: AKRT016746

Reaction: N=c1c2ncn([C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O)c2ncn1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O → NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c1N/C=N/[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

Substrate
→
Product
Source Link: HISTCYCLOHYD-RXN
Reaction ID: AKRT016747

Reaction: N=c1c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2ncn1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O → N=c1c2ncn([C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O)c2ncn1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

Substrate
→
Product
Source Link: HISTPRATPHYD-RXN
Reaction ID: AKRT020297

Reaction: N[C@H](CO)Cc1c[nH]cn1 → N[C@@H](Cc1c[nH]cn1)C(=O)O

Substrate
→
Product
Source Link: RXN-8001