Enzyme:

Enzyme Properties

EntryP50747 Entry NameBPL1_HUMAN
Protein NamesBiotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)]
Gene NamesHLCS OrganismHomo sapiens (Human)
EC NumbersEC 6.3.4.9; EC 6.3.4.10; EC 6.3.4.11; EC 6.3.4.15 Enzyme TypeLigases
Length726.0 aa Reviewed Reviewed
From SourceP50747

Associated Reactions

Reaction ID: AKRT021935

Reaction: O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 → Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@@H]32)[C@@H](O)[C@H]1O

Substrate
Product
Source Link: RXN0-7192
Reaction ID: AKRT021935

Reaction: Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O → Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@@H]32)[C@@H](O)[C@H]1O

Substrate
Product
Source Link: RXN0-7192
Reaction ID: AKRT000638

Reaction: O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 → *N[C@@H](CCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(*)=O

Substrate
Product
Source Link: 6.3.4.11-RXN
Reaction ID: AKRT000561

Reaction: O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 → *NC(=O)[C@H](CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC21)NC(*)=O

Substrate
Product
Source Link: 6.3.4.10-RXN
Reaction ID: AKRT000639

Reaction: O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 → *N[C@@H](CCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(*)=O

Substrate
Product
Source Link: BIOTINLIG-RXN