Phenazine 2
AlkaPlorer ID: AK000208
Synonym: 'Phenazine 2'
IUPAC Name: 2-bromo-5-(3-methylbut-2-enyl)phenazin-1-one
Structure
SMILES: CC(C)=CCN1C2=CC=C(Br)C(=O)C2=NC2=CC=CC=C21
InChI: InChI=1S/C17H15BrN2O/c1-11(2)9-10-20-14-6-4-3-5-13(14)19-16-15(20)8-7-12(18)17(16)21/h3-9H,10H2,1-2H3
InChIKey: SPXDZPBINDWJSY-UHFFFAOYSA-N
Reference
Novel Marine Phenazines as Potential Cancer Chemopreventive and Anti-Inflammatory Agents
PubChem CID: 132570350
LOTUS: LTS0148930
COCONUT: CNP0343017
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 343.22400000000005
TPSA？: 34.89
MolLogP？: 4.230000000000003
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HCT-116 | IC50 | 29.0 | nM | 10.1016/j.ejmech.2020.112957 |
| Mus musculus | RAW264.7 | IC50 | 890.0 | nM | 10.1016/j.bmc.2017.01.002 |
| Mus musculus | RAW264.7 | IC50 | 15100.0 | nM | 10.1016/j.bmc.2017.01.002 |
| None | Unchecked | IC50 | 24200.0 | nM | 10.1016/j.bmc.2017.01.002 |