Benzethonium Chloride
AlkaPlorer ID: AK000234
Synonym: None
IUPAC Name: benzyl-dimethyl-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium;chloride
Structure
SMILES: CC(C)(C)CC(C)(C)C1=CC=C(C=C1)OCCOCC[N+](C)(C)CC2=CC=CC=C2.[Cl-]
InChI: InChI=1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1
InChIKey: UREZNYTWGJKWBI-UHFFFAOYSA-M
Reference
Two New Alkaloids from the Roots of Aconitum sinomontanum<scp>Nakai</scp>
PubChem CID: 8478
CAS: 121-54-0
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 448.09100000000024
TPSA？: 18.46
MolLogP？: 3.0764000000000014
Number of H-Donors: 0
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Acanthamoeba lugdunensis | Acanthamoeba lugdunensis | MIC | 250000.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Acinetobacter baumannii | Acinetobacter baumannii | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Acinetobacter baumannii | Acinetobacter baumannii | MIC90 | 256.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Bacillus anthracis | Anthrax lethal factor | Potency | 6309.6 | nM | None |
| Bacillus subtilis | 4'-phosphopantetheinyl transferase ffp | Potency | 39810.7 | nM | None |
| Bos taurus | Progesterone receptor | IC50 | nan | None | None |
| Bos taurus | Progesterone receptor | Ki | nan | None | None |
| Candida albicans | Candida albicans | IC50 | 8700.0 | nM | 10.1021/acs.jmedchem.6b01203 |
| Candida albicans | Candida albicans | MIC | 35700.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Cavia porcellus | Leukotriene C4 synthase | IC50 | nan | None | None |
| Cavia porcellus | Leukotriene C4 synthase | Ki | nan | None | None |
| Cavia porcellus | Serotonin 4 (5-HT4) receptor | IC50 | nan | None | None |
| Cavia porcellus | Serotonin 4 (5-HT4) receptor | Ki | nan | None | None |
| Chlorocebus sabaeus | Vero | EC50 | 0.01 | ug.mL-1 | 10.1016/j.bmc.2011.04.023 |
| Enterococcus faecalis | Enterococcus faecalis | MIC90 | 4.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Enterococcus faecalis | Enterococcus faecalis | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Enterococcus faecium | Enterococcus faecium | MIC90 | 4.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Enterococcus faecium | Enterococcus faecium | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Equus caballus | Ferritin light chain | Potency | 50118.7 | nM | None |
| Escherichia coli | Escherichia coli | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Escherichia coli | Escherichia coli | MIC90 | 256.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Escherichia coli | GroEL/GroES | IC50 | 24000.0 | nM | 10.1016/j.bmcl.2019.02.028 |
| Escherichia coli | GroEL/GroES | IC50 | 26000.0 | nM | 10.1016/j.bmcl.2019.02.028 |
| Escherichia coli | GroEL/GroES | Inhibition | 62.0 | % | 10.1016/j.bmcl.2019.02.028 |
| Escherichia coli | GroEL/GroES | Inhibition | 72.0 | % | 10.1016/j.bmcl.2019.02.028 |
| Escherichia coli (strain K12) | 60 kDa chaperonin | IC50 | 250000.0 | nM | 10.1016/j.bmcl.2019.02.028 |
| Homo sapiens | 786-0 | GI50 | 5011.87 | nM | None |
| Homo sapiens | A498 | GI50 | 16634.13 | nM | None |
| Homo sapiens | A549 | GI50 | 8709.64 | nM | None |
| Homo sapiens | A549 | IC50 | 3200.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | A549 | Ratio IC50 | 10.0 | None | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | Acetylcholinesterase | IC50 | 2246.0 | nM | None |
| Homo sapiens | Acetylcholinesterase | Ki | nan | None | None |
| Homo sapiens | ACHN | GI50 | 11641.26 | nM | None |
| Homo sapiens | Adenosine A1 receptor | IC50 | nan | None | None |
| Homo sapiens | Adenosine A1 receptor | Ki | nan | None | None |
| Homo sapiens | Adenosine A2a receptor | IC50 | nan | None | None |
| Homo sapiens | Adenosine A2a receptor | Ki | nan | None | None |
| Homo sapiens | Adenosine A3 receptor | IC50 | nan | None | None |
| Homo sapiens | Adenosine A3 receptor | Ki | nan | None | None |
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 22387.2 | nM | None |
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 35481.3 | nM | None |
| Homo sapiens | Alpha-1d adrenergic receptor | IC50 | nan | None | None |
| Homo sapiens | Alpha-1d adrenergic receptor | Ki | nan | None | None |
| Homo sapiens | Alpha-2a adrenergic receptor | IC50 | 3102.0 | nM | None |
| Homo sapiens | Alpha-2a adrenergic receptor | Ki | 1163.0 | nM | None |
| Homo sapiens | Alpha-2b adrenergic receptor | IC50 | 643.0 | nM | None |
| Homo sapiens | Alpha-2b adrenergic receptor | Ki | 294.0 | nM | None |
| Homo sapiens | Alpha-2c adrenergic receptor | IC50 | 1961.0 | nM | None |
| Homo sapiens | Alpha-2c adrenergic receptor | Ki | 285.0 | nM | None |
| Homo sapiens | Alpha-synuclein | Potency | 22387.2 | nM | None |
| Homo sapiens | Androgen Receptor | Potency | 50118.7 | nM | None |
| Homo sapiens | Angiotensin II type 2 (AT-2) receptor | IC50 | nan | None | None |
| Homo sapiens | Angiotensin II type 2 (AT-2) receptor | Ki | nan | None | None |
| Homo sapiens | Apoptotic protease-activating factor 1 | IC50 | 23500.0 | nM | None |
| Homo sapiens | Apoptotic protease-activating factor 1 | IC50 | 100000.0 | nM | None |
| Homo sapiens | Ataxin-2 | Potency | 35481.3 | nM | None |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 580.2 | nM | None |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 35481.3 | nM | None |
| Homo sapiens | Beta-1 adrenergic receptor | IC50 | nan | None | None |
| Homo sapiens | Beta-1 adrenergic receptor | Ki | nan | None | None |
| Homo sapiens | Beta-2 adrenergic receptor | IC50 | nan | None | None |
| Homo sapiens | Beta-2 adrenergic receptor | Ki | nan | None | None |
| Homo sapiens | Beta-3 adrenergic receptor | IC50 | nan | None | None |
| Homo sapiens | Beta-3 adrenergic receptor | Ki | nan | None | None |
| Homo sapiens | Beta-glucocerebrosidase | Potency | 25118.9 | nM | None |
| Homo sapiens | Bile acid receptor FXR | Potency | 19952.6 | nM | None |
| Homo sapiens | Bile acid receptor FXR | Potency | 50118.7 | nM | None |
| Homo sapiens | Bradykinin B2 receptor | IC50 | nan | None | None |
| Homo sapiens | Bradykinin B2 receptor | Ki | nan | None | None |
| Homo sapiens | CAKI-1 | GI50 | 10139.11 | nM | None |
| Homo sapiens | Calcitonin receptor | IC50 | nan | None | None |
| Homo sapiens | Calcitonin receptor | Ki | nan | None | None |
| Homo sapiens | Cannabinoid CB1 receptor | IC50 | nan | None | None |
| Homo sapiens | Cannabinoid CB1 receptor | Ki | nan | None | None |
| Homo sapiens | Carbonic anhydrase II | IC50 | nan | None | None |
| Homo sapiens | Carbonic anhydrase II | Ki | nan | None | None |
| Homo sapiens | Caspase-1 | IC50 | nan | None | None |
| Homo sapiens | Caspase-1 | Ki | nan | None | None |
| Homo sapiens | Cathepsin G | IC50 | nan | None | None |
| Homo sapiens | Cathepsin G | Ki | nan | None | None |
| Homo sapiens | C-C chemokine receptor type 2 | IC50 | nan | None | None |
| Homo sapiens | C-C chemokine receptor type 2 | Ki | nan | None | None |
| Homo sapiens | C-C chemokine receptor type 4 | IC50 | nan | None | None |
| Homo sapiens | C-C chemokine receptor type 4 | Ki | nan | None | None |
| Homo sapiens | C-C chemokine receptor type 5 | IC50 | nan | None | None |
| Homo sapiens | C-C chemokine receptor type 5 | Ki | nan | None | None |
| Homo sapiens | CCRF-CEM | GI50 | 1794.73 | nM | None |
| Homo sapiens | CCRF-CEM | IC50 | 3800.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | CCRF-CEM | Ratio IC50 | 8.0 | None | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | Cellular tumor antigen p53 | Potency | 12589.3 | nM | None |
| Homo sapiens | Cellular tumor antigen p53 | Potency | 50118.7 | nM | None |
| Homo sapiens | Cholecystokinin A receptor | IC50 | nan | None | None |
| Homo sapiens | Cholecystokinin A receptor | Ki | nan | None | None |
| Homo sapiens | COLO 205 | GI50 | 1492.79 | nM | None |
| Homo sapiens | Cyclooxygenase-1 | IC50 | nan | None | None |
| Homo sapiens | Cyclooxygenase-1 | Ki | nan | None | None |
| Homo sapiens | Cyclooxygenase-2 | IC50 | nan | None | None |
| Homo sapiens | Cyclooxygenase-2 | Ki | nan | None | None |
| Homo sapiens | Cysteinyl leukotriene receptor 1 | IC50 | nan | None | None |
| Homo sapiens | Cysteinyl leukotriene receptor 1 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 1A2 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 1A2 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 2A6 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2A6 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 2C19 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2C19 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 2C9 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2C9 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 2D6 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2D6 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 2E1 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 2E1 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 3A4 | IC50 | nan | None | None |
| Homo sapiens | Cytochrome P450 3A4 | Ki | nan | None | None |
| Homo sapiens | Cytochrome P450 3A4 | Potency | 25118.9 | nM | None |
| Homo sapiens | Delta opioid receptor | IC50 | nan | None | None |
| Homo sapiens | Delta opioid receptor | Ki | nan | None | None |
| Homo sapiens | DLD-1 | GI50 | 4207.27 | nM | None |
| Homo sapiens | DMS-114 | GI50 | 1153.45 | nM | None |
| Homo sapiens | DMS-273 | GI50 | 1442.12 | nM | None |
| Homo sapiens | DNA-(apurinic or apyrimidinic site) lyase | Potency | 5011.9 | nM | None |
| Homo sapiens | DNA repair protein RAD52 homolog | AC50 | 31330.0 | nM | None |
| Homo sapiens | Dopamine D1 receptor | IC50 | nan | None | None |
| Homo sapiens | Dopamine D1 receptor | Ki | nan | None | None |
| Homo sapiens | Dopamine D2 receptor | IC50 | nan | None | None |
| Homo sapiens | Dopamine D2 receptor | Ki | nan | None | None |
| Homo sapiens | Dopamine D3 receptor | IC50 | nan | None | None |
| Homo sapiens | Dopamine D3 receptor | Ki | nan | None | None |
| Homo sapiens | Dopamine D4 receptor | IC50 | nan | None | None |
| Homo sapiens | Dopamine D4 receptor | Ki | nan | None | None |
| Homo sapiens | Dopamine transporter | IC50 | 1365.0 | nM | None |
| Homo sapiens | Dopamine transporter | Ki | 1085.0 | nM | None |
| Homo sapiens | EKVX | GI50 | 4197.59 | nM | None |
| Homo sapiens | Endothelin receptor ET-A | IC50 | nan | None | None |
| Homo sapiens | Endothelin receptor ET-A | Ki | nan | None | None |
| Homo sapiens | Enteropeptidase | Potency | 28183.8 | nM | None |
| Homo sapiens | Epidermal growth factor receptor erbB1 | IC50 | nan | None | None |
| Homo sapiens | Epidermal growth factor receptor erbB1 | Ki | nan | None | None |
| Homo sapiens | Estrogen receptor alpha | IC50 | nan | None | None |
| Homo sapiens | Estrogen receptor alpha | Ki | nan | None | None |
| Homo sapiens | Estrogen receptor alpha | Potency | 25118.9 | nM | None |
| Homo sapiens | Estrogen receptor alpha | Potency | 44668.4 | nM | None |
| Homo sapiens | Estrogen receptor beta | IC50 | nan | None | None |
| Homo sapiens | Estrogen receptor beta | Ki | nan | None | None |
| Homo sapiens | Geminin | Potency | 145.8 | nM | None |
| Homo sapiens | Geminin | Potency | 3264.3 | nM | None |
| Homo sapiens | Glucocorticoid receptor | IC50 | nan | None | None |
| Homo sapiens | Glucocorticoid receptor | Ki | nan | None | None |
| Homo sapiens | Glucocorticoid receptor | Potency | 22387.2 | nM | None |
| Homo sapiens | Glucocorticoid receptor | Potency | 28183.8 | nM | None |
| Homo sapiens | HCC 2998 | GI50 | 1496.24 | nM | None |
| Homo sapiens | HCT-116 | GI50 | 1706.08 | nM | None |
| Homo sapiens | HCT-15 | GI50 | 20511.62 | nM | None |
| Homo sapiens | HeLa | IC50 | 5700.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | HepG2 | Potency | 35481.3 | nM | None |
| Homo sapiens | HERG | IC50 | 108.5 | nM | None |
| Homo sapiens | HERG | Ki | 88.9 | nM | None |
| Homo sapiens | HERG | Potency | 2511.9 | nM | None |
| Homo sapiens | Histamine H1 receptor | IC50 | nan | None | None |
| Homo sapiens | Histamine H1 receptor | Ki | nan | None | None |
| Homo sapiens | Histamine H2 receptor | IC50 | nan | None | None |
| Homo sapiens | Histamine H2 receptor | Ki | nan | None | None |
| Homo sapiens | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Potency | 14125.4 | nM | None |
| Homo sapiens | HL-60 | GI50 | 883.08 | nM | None |
| Homo sapiens | HMG-CoA reductase | IC50 | nan | None | None |
| Homo sapiens | HMG-CoA reductase | Ki | nan | None | None |
| Homo sapiens | HOP-18 | GI50 | 2792.54 | nM | None |
| Homo sapiens | HOP-62 | GI50 | 8933.05 | nM | None |
| Homo sapiens | HOP-92 | GI50 | 1879.32 | nM | None |
| Homo sapiens | HSP60/HSP10 | IC50 | 23000.0 | nM | 10.1016/j.bmcl.2019.02.028 |
| Homo sapiens | HT-29 | GI50 | 1603.25 | nM | None |
| Homo sapiens | Huntingtin | Potency | 28183.8 | nM | None |
| Homo sapiens | HUVEC | IC50 | 47000.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | Hypoxia-inducible factor 1 alpha | Potency | 79432.8 | nM | None |
| Homo sapiens | IGROV-1 | GI50 | 1517.05 | nM | None |
| Homo sapiens | Interleukin-8 | Potency | 59557.2 | nM | None |
| Homo sapiens | Interleukin-8 receptor A | IC50 | nan | None | None |
| Homo sapiens | Interleukin-8 receptor A | Ki | nan | None | None |
| Homo sapiens | Interleukin-8 receptor B | IC50 | nan | None | None |
| Homo sapiens | Interleukin-8 receptor B | Ki | nan | None | None |
| Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic | Potency | 5804.8 | nM | None |
| Homo sapiens | K562 | GI50 | 2187.76 | nM | None |
| Homo sapiens | Kappa opioid receptor | IC50 | nan | None | None |
| Homo sapiens | Kappa opioid receptor | Ki | nan | None | None |
| Homo sapiens | KM12 | GI50 | 1614.36 | nM | None |
| Homo sapiens | KM-20L2 | GI50 | 3890.45 | nM | None |
| Homo sapiens | Leukocyte common antigen | IC50 | nan | None | None |
| Homo sapiens | Leukocyte common antigen | Ki | nan | None | None |
| Homo sapiens | Leukocyte elastase | IC50 | nan | None | None |
| Homo sapiens | Leukocyte elastase | Ki | nan | None | None |
| Homo sapiens | LOX IMVI | GI50 | 1415.79 | nM | None |
| Homo sapiens | LXFL 529 | GI50 | 1318.26 | nM | None |
| Homo sapiens | Lymphoblastoid cell | Potency | 15848.9 | nM | None |
| Homo sapiens | Lymphoblastoid cell | Potency | 19952.6 | nM | None |
| Homo sapiens | Lymphoblastoid cell | Potency | 25118.9 | nM | None |
| Homo sapiens | Lymphoblastoid cell | Potency | 31622.8 | nM | None |
| Homo sapiens | Lymphoblastoid cell | Potency | 39810.7 | nM | None |
| Homo sapiens | Lymphoblastoid cell | Potency | 50118.7 | nM | None |
| Homo sapiens | M14 | GI50 | 2084.49 | nM | None |
| Homo sapiens | M19-MEL | GI50 | 1531.09 | nM | None |
| Homo sapiens | Malme-3M | GI50 | 1524.05 | nM | None |
| Homo sapiens | MAP kinase ERK1 | IC50 | nan | None | None |
| Homo sapiens | MAP kinase ERK1 | Ki | nan | None | None |
| Homo sapiens | MAP kinase ERK2 | IC50 | nan | None | None |
| Homo sapiens | MAP kinase ERK2 | Ki | nan | None | None |
| Homo sapiens | MAP kinase p38 alpha | IC50 | nan | None | None |
| Homo sapiens | MAP kinase p38 alpha | Ki | nan | None | None |
| Homo sapiens | Matrix metalloproteinase-1 | IC50 | nan | None | None |
| Homo sapiens | Matrix metalloproteinase-1 | Ki | nan | None | None |
| Homo sapiens | Matrix metalloproteinase 9 | IC50 | nan | None | None |
| Homo sapiens | Matrix metalloproteinase 9 | Ki | nan | None | None |
| Homo sapiens | MCF7 | IC50 | 5000.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | MDA-MB-231 | IC50 | 4800.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| Homo sapiens | Melanocortin receptor 3 | IC50 | nan | None | None |
| Homo sapiens | Melanocortin receptor 3 | Ki | nan | None | None |
| Homo sapiens | Melanocortin receptor 4 | EC50 | 89188.0 | nM | None |
| Homo sapiens | Melanocortin receptor 4 | IC50 | nan | None | None |
| Homo sapiens | Melanocortin receptor 4 | Ki | nan | None | None |
| Homo sapiens | Melanocortin receptor 5 | IC50 | nan | None | None |
| Homo sapiens | Melanocortin receptor 5 | Ki | nan | None | None |
| Homo sapiens | Menin/Histone-lysine N-methyltransferase MLL | Potency | 3162.3 | nM | None |
| Homo sapiens | Metastin receptor | Activity | nan | None | 10.1021/jm0609824 |
| Homo sapiens | Metastin receptor | Ki | 3600.0 | nM | 10.1021/jm0609824 |
| Homo sapiens | Microtubule-associated protein tau | Potency | 25118.9 | nM | None |
| Homo sapiens | MOLT-4 | GI50 | 2223.31 | nM | None |
| Homo sapiens | Monoamine oxidase A | IC50 | nan | None | None |
| Homo sapiens | Monoamine oxidase A | Ki | nan | None | None |
| Homo sapiens | Mothers against decapentaplegic homolog 3 | Potency | 35481.3 | nM | None |
| Homo sapiens | Mu opioid receptor | IC50 | nan | None | None |
| Homo sapiens | Mu opioid receptor | Ki | nan | None | None |
| Homo sapiens | Muscarinic acetylcholine receptor M1 | IC50 | 412.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M1 | Ki | 99.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M2 | IC50 | 574.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M2 | Ki | 204.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M3 | IC50 | 383.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M3 | Ki | 81.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M4 | IC50 | 257.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M4 | Ki | 36.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M5 | IC50 | 134.0 | nM | None |
| Homo sapiens | Muscarinic acetylcholine receptor M5 | Ki | 96.0 | nM | None |
| Homo sapiens | NCI-H226 | GI50 | 5188.0 | nM | None |
| Homo sapiens | NCI-H23 | GI50 | 1663.41 | nM | None |
| Homo sapiens | NCI-H322M | GI50 | 10519.62 | nM | None |
| Homo sapiens | NCI-H460 | GI50 | 3047.89 | nM | None |
| Homo sapiens | NCI-H522 | GI50 | 1655.77 | nM | None |
| Homo sapiens | Neurokinin 1 receptor | IC50 | nan | None | None |
| Homo sapiens | Neurokinin 1 receptor | Ki | nan | None | None |
| Homo sapiens | Neurokinin 2 receptor | IC50 | 1925.0 | nM | None |
| Homo sapiens | Neurokinin 2 receptor | Ki | 642.0 | nM | None |
| Homo sapiens | Neuropeptide Y receptor type 1 | IC50 | nan | None | None |
| Homo sapiens | Neuropeptide Y receptor type 1 | Ki | nan | None | None |
| Homo sapiens | Neuropeptide Y receptor type 2 | IC50 | nan | None | None |
| Homo sapiens | Neuropeptide Y receptor type 2 | Ki | nan | None | None |
| Homo sapiens | Norepinephrine transporter | IC50 | 907.0 | nM | None |
| Homo sapiens | Norepinephrine transporter | Ki | 900.0 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 20596.2 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 37578.0 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 68589.6 | nM | None |
| Homo sapiens | Nuclear factor erythroid 2-related factor 2 | Potency | 74978.0 | nM | None |
| Homo sapiens | Nuclear factor NF-kappa-B p105 subunit | Potency | 39810.7 | nM | None |
| Homo sapiens | Nuclear factor NF-kappa-B p105 subunit | Potency | 44668.4 | nM | None |
| Homo sapiens | Nuclear receptor ROR-gamma | Potency | 42163.2 | nM | None |
| Homo sapiens | Opioid receptors; mu & delta | EC50 | 92461.0 | nM | None |
| Homo sapiens | OVCAR-3 | GI50 | 1520.55 | nM | None |
| Homo sapiens | OVCAR-4 | GI50 | 2060.63 | nM | None |
| Homo sapiens | OVCAR-5 | GI50 | 6165.95 | nM | None |
| Homo sapiens | OVCAR-8 | GI50 | 3191.54 | nM | None |
| Homo sapiens | Peroxisome proliferator-activated receptor delta | Potency | 15848.9 | nM | None |
| Homo sapiens | Peroxisome proliferator-activated receptor delta | Potency | 31622.8 | nM | None |
| Homo sapiens | Peroxisome proliferator-activated receptor gamma | Potency | 50118.7 | nM | None |
| Homo sapiens | Phosphodiesterase 5A | IC50 | nan | None | None |
| Homo sapiens | Phosphodiesterase 5A | Ki | nan | None | None |
| Homo sapiens | Platelet activating factor receptor | IC50 | nan | None | None |
| Homo sapiens | Platelet activating factor receptor | Ki | nan | None | None |
| Homo sapiens | Prelamin-A/C | Potency | 35481.3 | nM | None |
| Homo sapiens | Protein kinase C alpha | IC50 | nan | None | None |
| Homo sapiens | Protein kinase C alpha | Ki | nan | None | None |
| Homo sapiens | Receptor protein-tyrosine kinase erbB-2 | IC50 | 2084.0 | nM | None |
| Homo sapiens | Receptor protein-tyrosine kinase erbB-2 | Ki | nan | None | None |
| Homo sapiens | Retinoid X receptor alpha | Potency | 11220.2 | nM | None |
| Homo sapiens | Retinoid X receptor alpha | Potency | 22387.2 | nM | None |
| Homo sapiens | Retinoid X receptor alpha | Potency | 25118.9 | nM | None |
| Homo sapiens | Retinoid X receptor alpha | Potency | 35481.3 | nM | None |
| Homo sapiens | RPMI-8226 | GI50 | 1294.2 | nM | None |
| Homo sapiens | RXF 393 | GI50 | 3111.72 | nM | None |
| Homo sapiens | RXF 631 | GI50 | 11939.88 | nM | None |
| Homo sapiens | Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform | IC50 | nan | None | None |
| Homo sapiens | Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform | Ki | nan | None | None |
| Homo sapiens | Serotonin 2a (5-HT2a) receptor | IC50 | 129.0 | nM | None |
| Homo sapiens | Serotonin 2a (5-HT2a) receptor | Ki | 37.0 | nM | None |
| Homo sapiens | Serotonin 2b (5-HT2b) receptor | IC50 | nan | None | None |
| Homo sapiens | Serotonin 2b (5-HT2b) receptor | Ki | nan | None | None |
| Homo sapiens | Serotonin 2c (5-HT2c) receptor | IC50 | 1027.0 | nM | None |
| Homo sapiens | Serotonin 2c (5-HT2c) receptor | Ki | 538.0 | nM | None |
| Homo sapiens | Serotonin 6 (5-HT6) receptor | IC50 | nan | None | None |
| Homo sapiens | Serotonin 6 (5-HT6) receptor | Ki | nan | None | None |
| Homo sapiens | Serotonin transporter | IC50 | 2438.0 | nM | None |
| Homo sapiens | Serotonin transporter | Ki | 1295.0 | nM | None |
| Homo sapiens | SF-268 | GI50 | 1940.89 | nM | None |
| Homo sapiens | SF-295 | GI50 | 10964.78 | nM | None |
| Homo sapiens | SF-539 | GI50 | 2376.84 | nM | None |
| Homo sapiens | Sigma opioid receptor | IC50 | nan | None | None |
| Homo sapiens | Sigma opioid receptor | Ki | nan | None | None |
| Homo sapiens | SK-MEL-2 | GI50 | 2060.63 | nM | None |
| Homo sapiens | SK-MEL-28 | GI50 | 1857.8 | nM | None |
| Homo sapiens | SK-MEL-5 | GI50 | 1386.76 | nM | None |
| Homo sapiens | SK-OV-3 | GI50 | 7430.19 | nM | None |
| Homo sapiens | SN12C | GI50 | 3515.6 | nM | None |
| Homo sapiens | SNB-19 | GI50 | 3104.56 | nM | None |
| Homo sapiens | SNB-75 | GI50 | 2426.61 | nM | None |
| Homo sapiens | SNB-78 | GI50 | 1633.05 | nM | None |
| Homo sapiens | Solute carrier organic anion transporter family member 1B1 | Inhibition | 80.79 | % | 10.1124/mol.112.084152 |
| Homo sapiens | Solute carrier organic anion transporter family member 1B3 | Inhibition | 467.45 | % | 10.1124/mol.112.084152 |
| Homo sapiens | Sphingomyelin phosphodiesterase | Potency | 112201.8 | nM | None |
| Homo sapiens | SR | GI50 | 2027.68 | nM | None |
| Homo sapiens | Survival motor neuron protein | Potency | 19952.6 | nM | None |
| Homo sapiens | Survival motor neuron protein | Potency | 35481.3 | nM | None |
| Homo sapiens | SW-620 | GI50 | 2685.34 | nM | None |
| Homo sapiens | TAR DNA-binding protein 43 | Potency | 35481.3 | nM | None |
| Homo sapiens | Thiosulfate sulfurtransferase | IC50 | 100000.0 | nM | 10.1016/j.bmcl.2019.02.028 |
| Homo sapiens | Thromboxane-A synthase | IC50 | nan | None | None |
| Homo sapiens | Thromboxane-A synthase | Ki | nan | None | None |
| Homo sapiens | Thyroid hormone receptor beta-1 | Potency | 44668.4 | nM | None |
| Homo sapiens | Thyroid hormone receptor beta-1 | Potency | 50118.7 | nM | None |
| Homo sapiens | Thyroid stimulating hormone receptor | Potency | 39810.7 | nM | None |
| Homo sapiens | TK-10 | GI50 | 3639.15 | nM | None |
| Homo sapiens | Tyrosine-protein kinase FYN | IC50 | 768.0 | nM | None |
| Homo sapiens | Tyrosine-protein kinase FYN | Ki | nan | None | None |
| Homo sapiens | Tyrosine-protein kinase LCK | IC50 | nan | None | None |
| Homo sapiens | Tyrosine-protein kinase LCK | Ki | nan | None | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 1678.9 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 2371.5 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 2909.3 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 3264.3 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 3662.6 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 4109.5 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 35481.3 | nM | None |
| Homo sapiens | U-251 | GI50 | 1541.7 | nM | None |
| Homo sapiens | UACC-257 | GI50 | 1445.44 | nM | None |
| Homo sapiens | UACC-62 | GI50 | 1355.19 | nM | None |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 1 | Potency | 56234.1 | nM | None |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 2 | Potency | 23280.9 | nM | None |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 2 | Potency | 28183.8 | nM | None |
| Homo sapiens | Ubiquitin-conjugating enzyme E2 N | IC50 | 20000.0 | nM | None |
| Homo sapiens | UO-31 | GI50 | 21627.19 | nM | None |
| Homo sapiens | Vascular endothelial growth factor receptor 1 | IC50 | nan | None | None |
| Homo sapiens | Vascular endothelial growth factor receptor 1 | Ki | nan | None | None |
| Homo sapiens | Vasoactive intestinal polypeptide receptor 1 | IC50 | nan | None | None |
| Homo sapiens | Vasoactive intestinal polypeptide receptor 1 | Ki | nan | None | None |
| Homo sapiens | Vasopressin V1a receptor | IC50 | nan | None | None |
| Homo sapiens | Vasopressin V1a receptor | Ki | nan | None | None |
| Homo sapiens | Vitamin D receptor | Potency | 44668.4 | nM | None |
| Homo sapiens | XF498 | GI50 | 376.7 | nM | None |
| Klebsiella pneumoniae | Klebsiella pneumoniae | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Klebsiella pneumoniae | Klebsiella pneumoniae | MIC90 | 256.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Mus musculus | Nitric oxide synthase, inducible | IC50 | nan | None | None |
| Mus musculus | Nitric oxide synthase, inducible | Ki | nan | None | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 22387.2 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 25118.9 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 31622.8 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 35481.3 | nM | None |
| Oryctolagus cuniculus | Angiotensin-converting enzyme | IC50 | nan | None | None |
| Oryctolagus cuniculus | Angiotensin-converting enzyme | Ki | nan | None | None |
| Oryctolagus cuniculus | Arachidonate 15-lipoxygenase | IC50 | nan | None | None |
| Oryctolagus cuniculus | Arachidonate 15-lipoxygenase | Ki | nan | None | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 465.4 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 928.5 | nM | None |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC90 | 64.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC90 | 512.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Rattus norvegicus | Aldose reductase | IC50 | nan | None | None |
| Rattus norvegicus | Aldose reductase | Ki | nan | None | None |
| Rattus norvegicus | Alpha-1a adrenergic receptor | IC50 | nan | None | None |
| Rattus norvegicus | Alpha-1a adrenergic receptor | Ki | nan | None | None |
| Rattus norvegicus | Alpha-1b adrenergic receptor | IC50 | nan | None | None |
| Rattus norvegicus | Alpha-1b adrenergic receptor | Ki | nan | None | None |
| Rattus norvegicus | Androgen Receptor | IC50 | nan | None | None |
| Rattus norvegicus | Androgen Receptor | Ki | nan | None | None |
| Rattus norvegicus | Glycine receptor | IC50 | nan | None | None |
| Rattus norvegicus | Glycine receptor | Ki | nan | None | None |
| Rattus norvegicus | Inositol monophosphatase 1 | Potency | 11220.2 | nM | None |
| Rattus norvegicus | INS1 | AC50 | 2896.0 | nM | None |
| Rattus norvegicus | Insulin receptor | IC50 | nan | None | None |
| Rattus norvegicus | Insulin receptor | Ki | nan | None | None |
| Rattus norvegicus | Nitric-oxide synthase, brain | IC50 | nan | None | None |
| Rattus norvegicus | Nitric-oxide synthase, brain | Ki | nan | None | None |
| Rattus norvegicus | Rattus norvegicus | ALB | 22700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 26300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 34700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 37000.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 40200.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 42300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 42700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALB | 43000.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 269.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 275.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 295.17 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 323.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 343.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 346.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 351.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALP | 363.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 24.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 31.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 45.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 48.83 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 51.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 54.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | ALT | 63.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 71.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 74.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 75.83 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 89.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 89.83 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 90.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | AST | 103.17 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BASO | 0.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BASOLE | 0.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BILI | 1.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BILI | 1.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BILI | 1.8 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BILI | 2.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BILI | 2.2 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BILI | 2.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 116.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 146.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 153.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 155.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 156.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 165.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | BUN | 176.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 98.33 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 99.5 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 101.0 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 101.67 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 102.33 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 103.0 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHLORIDE | 103.5 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 413.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 450.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 705.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 706.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 725.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 761.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 825.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CHOL | 833.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 122.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 130.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 166.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 205.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 532.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 533.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 560.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CK | 651.83 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 21670000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 23000000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 27170000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 27330000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 28000000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 29330000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 29830000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CO2 | 30500000.0 | nM | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CREAT | 1.1 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CREAT | 1.5 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CREAT | 1.8 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CREAT | 2.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CREAT | 2.2 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | CREAT | 2.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOS | 0.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOS | 20.17 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOS | 22.83 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOS | 41.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOS | 92.33 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOS | 149.33 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOSLE | 0.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOSLE | 0.17 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOSLE | 0.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | EOSLE | 0.67 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1173.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1406.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1493.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1496.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1526.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1685.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | GLUC | 1806.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 29.43 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 31.77 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 33.43 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 34.13 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 34.38 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 34.85 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 36.05 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HCT | 36.62 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 114300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 118700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 126300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 126700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 129700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 133200.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 136200.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | HGB | 140700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 78.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 105.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 116.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 124.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 156.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 165.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 220.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LDH | 536.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LIPASE | 7.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LIPASE | 8.67 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LIPASE | 9.33 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LIPASE | 10.0 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LIPASE | 11.17 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LIPASE | 11.5 | U.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 10787.33 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 12202.83 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 12245.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 12247.5 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 12371.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 12736.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 15440.33 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYM | 16956.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 55.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 83.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 85.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 87.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 88.5 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 89.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | LYMLE | 89.5 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.0 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.13 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.73 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.78 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.83 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.87 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 23.95 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCH | 24.42 | pg | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 371000.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 372200.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 373700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 378000.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 384300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 387000.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCHC | 388700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 61.07 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 61.93 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 62.03 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 62.28 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 63.05 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 63.07 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 63.13 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MCV | 63.93 | fL | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 158.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 166.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 253.5 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 380.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 389.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 415.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 579.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONO | 1299.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 1.17 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 1.83 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 2.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 2.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 2.67 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 4.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | MONOLE | 6.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 8.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 8.83 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 9.17 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 9.33 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 10.17 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 12.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 12.67 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTLE | 39.0 | % | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 1193.17 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 1283.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 1292.17 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 1320.5 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 1437.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 1766.33 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 2446.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | NEUTSG | 8588.67 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PHOS | 109.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PHOS | 112.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PHOS | 112.5 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PHOS | 112.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PHOS | 114.8 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PHOS | 120.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 981000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1174000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1193500.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1198000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1322170.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1329670.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1372000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PLAT | 1520670.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 5.61 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 5.95 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 6.02 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 6.17 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 6.29 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 6.59 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 6.78 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | POTASSIUM | 7.21 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PROT | 53000.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PROT | 57300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PROT | 57700.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PROT | 59300.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PROT | 60500.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | PROT | 61200.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 4820000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5130000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5300000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5450000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5460000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5500000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5720000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBC | 5880000.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBCNUC | 0.0 | /100WBC | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | RBCNUC | 0.17 | /100WBC | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 140.5 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 140.53 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 142.5 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 142.62 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 142.67 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 143.1 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 143.77 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | SODIUM | 144.55 | mEq.L-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | Tissue Severity Score | nan | None | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | URATE | 14.2 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | URATE | 14.5 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | URATE | 15.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | URATE | 17.7 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | URATE | 18.3 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | URATE | 24.0 | ug.mL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 13130.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 13670.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 13850.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 14050.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 14180.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 17330.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 19930.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Rattus norvegicus | WBC | 22130.0 | cells.uL-1 | 10.6019/CHEMBL3885881 |
| Rattus norvegicus | Serotonin 1a (5-HT1a) receptor | IC50 | nan | None | None |
| Rattus norvegicus | Serotonin 1a (5-HT1a) receptor | Ki | nan | None | None |
| Rattus norvegicus | Serotonin 1b (5-HT1b) receptor | IC50 | nan | None | None |
| Rattus norvegicus | Serotonin 1b (5-HT1b) receptor | Ki | nan | None | None |
| Saccharomyces cerevisiae | Saccharomyces cerevisiae | Potency | 25118.9 | nM | None |
| Severe acute respiratory syndrome coronavirus 2 | Replicase polyprotein 1ab | Inhibition | 7.701 | % | 10.6019/CHEMBL4495564 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | -0.08 | % | 10.6019/CHEMBL4495565 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | 5.43 | % | 10.21203/rs.3.rs-23951/v1 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition index | 0.6042 | None | 10.1101/2020.04.03.023846 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | 33.0 | % | 10.1021/jm501628s |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 0.5 | ug.mL-1 | 10.1128/aac.01065-09 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 4.0 | ug.mL-1 | 10.1128/aac.01065-09 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 8.0 | ug.mL-1 | 10.1128/aac.01065-09 |
| Staphylococcus aureus | Staphylococcus aureus | MIC90 | 2.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Staphylococcus aureus | Staphylococcus aureus | MIC90 | 16.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Staphylococcus aureus | Staphylococcus aureus | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Staphylococcus aureus | Staphylococcus aureus | Survival | 0.0 | % | 10.1021/jm501628s |
| Staphylococcus epidermidis | Staphylococcus epidermidis | MIC90 | 2.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Staphylococcus epidermidis | Staphylococcus epidermidis | MIC90 | 8.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Staphylococcus epidermidis | Staphylococcus epidermidis | MIC90 | 128.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Stenotrophomonas maltophilia | Stenotrophomonas maltophilia | MIC90 | 32.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Stenotrophomonas maltophilia | Stenotrophomonas maltophilia | MIC90 | 256.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Streptococcus pneumoniae | Streptococcus pneumoniae | MIC90 | 2.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| Streptococcus pneumoniae | Streptococcus pneumoniae | MIC90 | 16.0 | ug.mL-1 | 10.1016/j.bmcl.2012.01.025 |
| None | ADMET | Activity | 77.3 | % | 10.1016/j.bmcl.2012.01.025 |
| None | Molecular identity unknown | Potency | 35481.3 | nM | None |
| None | Molecular identity unknown | Potency | 50118.7 | nM | None |
| None | Unchecked | Ac50 | 2.512 | uM | None |
| None | Unchecked | Ac50 | 14.13 | uM | None |
| None | Unchecked | Ac50 | 39.81 | uM | None |
| None | Unchecked | AC50 | 2511.9 | nM | None |
| None | Unchecked | AC50 | 14125.4 | nM | None |
| None | Unchecked | AC50 | 39810.7 | nM | None |
| None | Unchecked | CC50 | 40000.0 | nM | None |
| None | Unchecked | EC50 | 1680.0 | nM | None |
| None | Unchecked | EC50 | 2380.0 | nM | None |
| None | Unchecked | FICI | 1.0 | None | 10.1021/acs.jmedchem.7b00156 |
| None | Unchecked | IC50 | 114.0 | nM | None |
| None | Unchecked | IC50 | 254.0 | nM | None |
| None | Unchecked | IC50 | 452.0 | nM | None |
| None | Unchecked | IC50 | 1403.0 | nM | None |
| None | Unchecked | IC50 | 3736.1 | nM | None |
| None | Unchecked | IC50 | 7976.66 | nM | None |
| None | Unchecked | IC50 | 13787.9 | nM | None |
| None | Unchecked | IC50 | 20360.0 | nM | None |
| None | Unchecked | IC50 | 21590.0 | nM | None |
| None | Unchecked | IC50 | 21887.38 | nM | None |
| None | Unchecked | IC50 | 26170.0 | nM | None |
| None | Unchecked | IC50 | 32760.0 | nM | None |
| None | Unchecked | IC50 | 34892.0 | nM | None |
| None | Unchecked | IC50 | 35920.0 | nM | None |
| None | Unchecked | IC50 | 42800.0 | nM | None |
| None | Unchecked | IC50 | 46700.0 | nM | None |
| None | Unchecked | IC50 | 47110.0 | nM | None |
| None | Unchecked | IC50 | 63000.0 | nM | 10.1016/j.bmcl.2019.02.028 |
| None | Unchecked | IC50 | nan | None | None |
| None | Unchecked | Ki | 70.0 | nM | None |
| None | Unchecked | Ki | 232.0 | nM | None |
| None | Unchecked | Ki | 439.0 | nM | None |
| None | Unchecked | Ki | 1247.0 | nM | None |
| None | Unchecked | Ki | nan | None | None |
| None | Unchecked | MIC | 500000.0 | nM | 10.1016/j.ejmech.2013.05.033 |
| None | Unchecked | Potency | 8912.5 | nM | None |
| None | Unchecked | Potency | 11220.2 | nM | None |
| None | Unchecked | Potency | 12589.3 | nM | None |
| None | Unchecked | Potency | 14125.4 | nM | None |
| None | Unchecked | Potency | 16360.1 | nM | None |
| None | Unchecked | Potency | 17782.8 | nM | None |
| None | Unchecked | Potency | 22387.2 | nM | None |
| None | Unchecked | Potency | 25118.9 | nM | None |
| None | Unchecked | Potency | 25929.0 | nM | None |
| None | Unchecked | Potency | 28183.8 | nM | None |
| None | Unchecked | Potency | 31622.8 | nM | None |
| None | Unchecked | Ratio IC50 | 1.0 | None | 10.1016/j.bmcl.2019.02.028 |