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name Structure Reference Source Properties Activities Metabolism

Imperialine

AlkaPlorer ID: AK000314

Synonym: None

IUPAC Name: None

Structure

SMILES: C[C@H]1CC[C@@H]2[NH+](C1)C[C@H]1[C@@H]3C[C@H]4[C@@H](CC(=O)[C@H]5C[C@@H](O)CC[C@@]54C)[C@@H]3CC[C@H]1[C@]2(C)O

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InChI: InChI=1S/C27H43NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-23,25,29,31H,4-14H2,1-3H3/p+1/t15-,16-,17+,18+,19-,20-,21+,22-,23+,25-,26+,27-/m0/s1

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InChIKey: IQDIERHFZVCNRZ-LRCDAWNTSA-O

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Fritillaria imperialis Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria verticillata Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Boletinus cavipes Boletinus Gyrodontaceae Boletales Agaricomycetes Basidiomycota Fungi Eukaryota
Isochrysis galbana Isochrysis Isochrysidaceae Isochrysidales None Haptophyta None Eukaryota
Cenchrus setaceus Cenchrus Poaceae Poales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Trichopezizella barbata Trichopezizella Solenopeziaceae Helotiales Leotiomycetes Ascomycota Fungi Eukaryota
Fritillaria pallidiflora Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Choristoneura rosaceana Choristoneura Tortricidae Lepidoptera Insecta Arthropoda Metazoa Eukaryota
Fritillaria taipaiensis Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Salvia macrosiphon Salvia Lamiaceae Lamiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria thunbergii Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Angelica taiwaniana Angelica Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria przewalskii Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria cirrhosa Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Caragana stenophylla Caragana Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Saposhnikovia divaricata Saposhnikovia Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria unibracteata Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Conoideocrella tenuis Conoideocrella Clavicipitaceae Hypocreales Sordariomycetes Ascomycota Fungi Eukaryota
Acacia trineura Acacia Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Seseli yunnanense Seseli Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria walujewii Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Strophanthus divaricatus Strophanthus Apocynaceae Gentianales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Murraya paniculata Murraya Rutaceae Sapindales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pleurospermum rivulorum Pleurospermum Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Diospyros lotus Diospyros Ebenaceae Ericales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Fritillaria delavayi Fritillaria Liliaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 430.65300000000025

TPSA？: 61.97

MolLogP？: 2.4692000000000003

Number of H-Donors: 3

Number of H-Acceptors: 3

RingCount: 6

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Electrophorus electricus Acetylcholinesterase IC50 100000.0 nM 10.1016/j.ejmech.2017.06.007
Electrophorus electricus Acetylcholinesterase Inhibition 24.89 % 10.1016/j.bmc.2012.09.040
Equus caballus Cholinesterase IC50 100000.0 nM 10.1016/j.ejmech.2017.06.007
Equus caballus Cholinesterase Inhibition 6.5 % 10.1016/j.bmc.2012.09.040
Rattus norvegicus Trachea Activity 0.48 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 0.49 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 0.5 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 0.52 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 0.55 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 0.58 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 2.41 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 2.42 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 2.43 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 2.44 g 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 5.7 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 6.0 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 6.3 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 6.4 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 6.8 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 7.2 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 14.5 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 28.1 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 35.3 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 40.4 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 45.7 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Activity 50.7 % 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea EC50 4400.0 nM 10.1016/j.bmcl.2016.03.001
Rattus norvegicus Trachea Kd 3.89 nM 10.1016/j.bmcl.2016.03.001
None Unchecked Potency 35481.3 nM None

Metabolism Information