Rodiasine
AlkaPlorer ID: AK000362
Synonym: None
IUPAC Name: (1R,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-23-oxa-15,30-diazaheptacyclo[22.6.2.13,7.18,12.114,18.027,31.022,33]pentatriaconta-3(35),4,6,8,10,12(34),18,20,22(33),24,26,31-dodecaen-6-ol
Structure
SMILES: COC1=CC2=C3C=C1OC1=C4C(=CC(OC)=C1OC)CCN(C)[C@H]4CC1=CC=C(OC)C(=C1)C1=CC(=CC=C1O)C[C@H]3N(C)CC2
InChI: InChI=1S/C38H42N2O6/c1-39-13-11-24-19-33(43-4)34-21-26(24)29(39)17-22-7-9-31(41)27(15-22)28-16-23(8-10-32(28)42-3)18-30-36-25(12-14-40(30)2)20-35(44-5)37(45-6)38(36)46-34/h7-10,15-16,19-21,29-30,41H,11-14,17-18H2,1-6H3/t29-,30+/m1/s1
InChIKey: HIQZXOFBXJICTD-IHLOFXLRSA-N
Reference
Isolation and Antimalarial Activity of Alkaloids from<i>Pseudoxandra cuspidata</i>
PubChem CID: 442345
CAS: 6391-64-6
LOTUS: LTS0260323
NPASS: NPC95426
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Pseudoxandra cuspidata | Pseudoxandra | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 622.7620000000001
TPSA？: 72.86
MolLogP？: 6.742700000000008
Number of H-Donors: 1
Number of H-Acceptors: 8
RingCount: 7
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 1140.0 | nM | 10.1016/j.bmc.2009.02.050 |