Diaporphasine B
AlkaPlorer ID: AK000384
Synonym: None
IUPAC Name: methyl 6,7-dimethoxy-3-methyl-10-oxochromeno[3,2-c]pyridine-9-carboxylate
Structure
SMILES: CC1=CC2=C(C=N1)C(=O)C3=C(O2)C(=C(C=C3C(=O)OC)OC)OC
InChI: InChI=1S/C17H15NO6/c1-8-5-11-10(7-18-8)14(19)13-9(17(20)23-4)6-12(21-2)15(22-3)16(13)24-11/h5-7H,1-4H3
InChIKey: DSIZIDLZALKUMH-UHFFFAOYSA-N
Reference
Alkaloids from the mangrove endophytic fungus Diaporthe phaseolorum SKS019
PubChem CID: 137658545
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Diaporthe phaseolorum | Diaporthe | Diaporthaceae | Diaporthales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 329.30800000000005
TPSA？: 87.86000000000001
MolLogP？: 2.4534200000000004
Number of H-Donors: 0
Number of H-Acceptors: 7
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HCT-116 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | HCT-116 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | HepG2 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | HepG2 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MCF-10A | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MCF-10A | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MDA-MB-435 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MDA-MB-435 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | NCI-H460 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | NCI-H460 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |