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1-Butylisochromeno[3,4-C]pyrazol-5(3h)-One

AlkaPlorer ID: AK000458

Synonym: None

IUPAC Name: 1-butyl-2H-isochromeno[3,4-c]pyrazol-5-one

Structure

SMILES: CCCCC1=C2C3=CC=CC=C3C(=O)OC2=NN1

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InChI: InChI=1S/C14H14N2O2/c1-2-3-8-11-12-9-6-4-5-7-10(9)14(17)18-13(12)16-15-11/h4-7H,2-3,8H2,1H3,(H,15,16)

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InChIKey: YKYPXFBQABKRKC-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 242.278

TPSA？: 58.89

MolLogP？: 3.0119000000000007

Number of H-Donors: 1

Number of H-Acceptors: 3

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Bromodomain-containing protein 1 Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens Bromodomain-containing protein 4 Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens Probable global transcription activator SNF2L2 Activity nan None 10.1021/acs.jmedchem.6b00355
Homo sapiens Probable global transcription activator SNF2L2 Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens Protein polybromo-1 Activity nan None 10.1021/acs.jmedchem.6b00355
Homo sapiens Protein polybromo-1 Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens Protein polybromo-1 Inhibition nan % 10.1021/acs.jmedchem.6b00355
Homo sapiens Protein polybromo-1 Kd 5100.0 nM 10.1021/acs.jmedchem.6b00355
Homo sapiens Protein polybromo-1 T1/2 0.0005556 hr 10.1021/acs.jmedchem.6b00355
Homo sapiens Transcription activator BRG1 Activity nan None 10.1021/acs.jmedchem.6b00355
Homo sapiens Transcription activator BRG1 Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens Transcription initiation factor TFIID subunit 1 Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens Transcription initiation factor TFIID subunit 1-like Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355
Homo sapiens U2OS Activity nan None 10.1021/acs.jmedchem.6b00355
None NON-PROTEIN TARGET Activity nan None 10.1021/acs.jmedchem.6b00355
None Unchecked Activity nan None 10.1021/acs.jmedchem.6b00355
None Unchecked Delta Tm 2.0 degrees C 10.1021/acs.jmedchem.6b00355

Metabolism Information