arauridine
AlkaPlorer ID: AK000459
Synonym: '', 'Urd', '26287-69-4', 'Spongouridine', '3083-77-0', 'URIDINE', '1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione', 'uridine', '1-beta-D-ribofuranosyluracil', '2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-', 'u', 'Uridine', 'SMR000677923', '58-96-8', 'beta-Uridine', 'MLS006011814', 'Uridin', 'Uracil, 1-beta-D-arabinofuranosyl-'
IUPAC Name: 1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Structure
SMILES: O=C1C=CN([C@@H]2O[C@H](CO)[C@H](O)[C@@H]2O)C(=O)N1
InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6+,7+,8-/m1/s1
InChIKey: DRTQHJPVMGBUCF-YDKYIBAVSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 244.20300000000003
TPSA？: 124.78
MolLogP？: -2.8519
Number of H-Donors: 4
Number of H-Acceptors: 7
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | MCC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Chlorocebus sabaeus | Vero | MIC | 100.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Chlorocebus sabaeus | Vero | MIC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Homo sapiens | HeLa | MCC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Homo sapiens | HeLa | MIC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Homo sapiens | WI-38 | MCC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Homo sapiens | WI-38 | MIC | 100.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Homo sapiens | WI-38 | MIC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| Macacine herpesvirus 1 | Thymidine kinase | Activity | nan | None | 10.1128/aac.01284-06 |
| Oryctolagus cuniculus | Oryctolagus cuniculus | MIC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |
| None | ADMET | MCC | 400.0 | ug.mL-1 | 10.1021/jm00389a005 |