3H-pyrrolo[2,3-c]quinoline
AlkaPlorer ID: AK000471
Synonym: None
IUPAC Name: 3H-pyrrolo[2,3-c]quinoline
Structure
SMILES: C1=CC=C2C(=C1)C3=C(C=N2)NC=C3
InChI: InChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-11(9)7-13-10/h1-7,12H
InChIKey: BSUNEUGPXRSCLF-UHFFFAOYSA-N
Reference
Previously Uncultured Marine Bacteria Linked to Novel Alkaloid Production
PubChem CID: 46228106
CAS: 232-86-0
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 168.19899999999998
TPSA？: 28.68
MolLogP？: 2.7161
Number of H-Donors: 1
Number of H-Acceptors: 1
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania donovani | Leishmania donovani | IC50 | 182700.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 6400.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Rattus norvegicus | L6 | IC50 | 173200.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 25500.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 81000.0 | nM | 10.1016/j.bmc.2009.08.057 |
| None | Unchecked | IC50 | 27000.0 | nM | 10.1016/j.bmc.2009.08.057 |