Molecule

Australine

AlkaPlorer ID: AK000545

Synonym: 'Australine', '', '3,7a-Diepialexine', 'Alexine', '1-epialexine', '3-epi-Australine'

IUPAC Name: (1R,2R,3R,7S,8R)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol

SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21

InChI: InChI=1S/C8H15NO4/c10-3-4-7(12)8(13)6-5(11)1-2-9(4)6/h4-8,10-13H,1-3H2/t4-,5+,6-,7-,8-/m1/s1

InChIKey: AIQMLBKBQCVDEY-OZRXBMAMSA-N

PubChem CID: 442628

CAS: 118396-02-4

LOTUS: LTS0273906

SuperNatural Ⅲ: SN0006673-05

NPASS: NPC294883

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Santolina pectinata	Santolina	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Helichrysum drakensbergense	Helichrysum	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Piper divaricatum	Piper	Piperaceae	Piperales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Erythrina speciosa	Erythrina	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Prunus prostrata	Prunus	Rosaceae	Rosales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Prosopis africana	Prosopis	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Richteria pyrethroides	Richteria	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Commiphora sphaerocarpa	Commiphora	Burseraceae	Sapindales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Plakortis angulospiculatus	Plakortis	Plakinidae	Homosclerophorida	Homoscleromorpha	Porifera	Metazoa	Eukaryota

Molecule Weight: 189.211

TPSA？: 84.16

MolLogP？: -2.4821

Number of H-Donors: 4

Number of H-Acceptors: 5

RingCount: 2

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	Lysosomal alpha-glucosidase	Potency	15848.9	nM	None
Homo sapiens	Lysosomal alpha-glucosidase	Potency	28183.8	nM	None
Homo sapiens	Thyroid hormone receptor beta-1	Potency	35.5	nM	None
None	Unchecked	IC50	5800.0	nM	10.1021/acs.jnatprod.8b00879