Jamaicamide A
AlkaPlorer ID: AK000662
Synonym: 'Jamaicamide A', '(+)-Jamaicamide A'
IUPAC Name: (E,9E)-14-bromo-9-(chloromethylidene)-N-[(E)-3-methoxy-5-[(2S)-2-methyl-5-oxo-2H-pyrrol-1-yl]-5-oxopent-3-enyl]-6-methyltetradec-4-en-13-ynamide
Structure
SMILES: CO/C(=C/C(=O)N1C(=O)C=C[C@@H]1C)CCNC(=O)CC/C=C/C(C)CC/C(=C/Cl)CCCC#CBr
InChI: InChI=1S/C27H36BrClN2O4/c1-21(12-14-23(20-29)10-5-4-8-17-28)9-6-7-11-25(32)30-18-16-24(35-3)19-27(34)31-22(2)13-15-26(31)33/h6,9,13,15,19-22H,4-5,7,10-12,14,16,18H2,1-3H3,(H,30,32)/b9-6+,23-20+,24-19+/t21?,22-/m0/s1
InChIKey: NAIKIJSSBJHCBL-VIPNTUGYSA-N
Reference
Metabolomic Profiling and Genomic Study of a Marine Sponge-Associated Streptomyces sp.
PubChem CID: 49787031
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 567.9520000000005
TPSA？: 75.71000000000001
MolLogP？: 5.738000000000006
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| None | Unchecked | IC50 | 5000.0 | nM | 10.1016/j.bmc.2020.115792 |