Molecule

Conessine

AlkaPlorer ID: AK000709

Synonym: None

IUPAC Name: dimethyl-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azoniapentacyclo[10.8.0.02,9.05,9.013,18]icos-18-en-16-yl]azanium

Structure

SMILES: C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H]([NH+](C)C)CC[C@]5(C)[C@H]4CC[C@]23C[NH+]1C

InChI: InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/p+2/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1

InChIKey: GPLGAQQQNWMVMM-MYAJQUOBSA-P

Reference

Alkaloids from callus cultures of Holarrhena floribunda

LOTUS: LTS0085117

SuperNatural Ⅲ: SN0111881-13

NPASS: NPC7214

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Mentha suaveolens	Mentha	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Elsholtzia stauntonii	Elsholtzia	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Flindersia australis	Flindersia	Rutaceae	Sapindales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Piper hostmannianum	Piper	Piperaceae	Piperales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Diplospora dubia	Diplospora	Rubiaceae	Gentianales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Prostanthera prunelloides	Prostanthera	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Funtumia elastica	Funtumia	Apocynaceae	Gentianales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Asparagus setaceus	Asparagus	Asparagaceae	Asparagales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Heliotropium angiospermum	Heliotropium	Heliotropiaceae	Boraginales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Vincetoxicum stauntonii	Vincetoxicum	Apocynaceae	Gentianales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Bidens parviflora	Bidens	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Anisocycla grandidieri	Anisocycla	Menispermaceae	Ranunculales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Alpinia formosana	Alpinia	Zingiberaceae	Zingiberales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Protea compacta	Protea	Proteaceae	Proteales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Holarrhena pubescens	Holarrhena	Apocynaceae	Gentianales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Pinus bungeana	Pinus	Pinaceae	Pinales	Pinopsida	Streptophyta	Viridiplantae	Eukaryota
Typhonium flagelliforme	Typhonium	Araceae	Alismatales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Rubus moluccanus	Rubus	Rosaceae	Rosales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Bambusa tulda	Bambusa	Poaceae	Poales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Leucas volkensii	Leucas	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Westiellopsis prolifica	Westiellopsis	Hapalosiphonaceae	Nostocales	Cyanophyceae	Cyanobacteriota	None	Bacteria

Properties Information

Molecule Weight: 358.61400000000015

TPSA？: 8.88

MolLogP？: 1.975400000000002

Number of H-Donors: 2

Number of H-Acceptors: 0

RingCount: 5

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Bacillus anthracis	Anthrax lethal factor	Potency	6309.6	nM	None
Cavia porcellus	Histamine H3 receptor	Kd	281.84	nM	10.1021/jm8003625
Chlorocebus sabaeus	Vero C1008	CC50	34700.0	nM	10.6019/CHEMBL4651402
Chlorocebus sabaeus	Vero C1008	pCC50	4.46	None	10.6019/CHEMBL4651402
Electrophorus electricus	Acetylcholinesterase	Inhibition	29.95	%	10.1016/j.bmc.2012.09.040
Entamoeba histolytica	Entamoeba histolytica	IC50	8.97	ug.mL-1	10.1007/s00044-011-9767-1
Equus caballus	Cholinesterase	Inhibition	45.25	%	10.1016/j.bmc.2012.09.040
Homo sapiens	Adhesion G-protein coupled receptor F1	%Inhib (Mean)	-9.69	%	10.6019/CHEMBL5209801
Homo sapiens	Adhesion G-protein coupled receptor F1	%Max (Mean)	3.031	%	10.6019/CHEMBL5209801
Homo sapiens	Alpha-2a adrenergic receptor	%Inhib (Mean)	17.3	%	10.6019/CHEMBL5209801
Homo sapiens	Alpha-2a adrenergic receptor	Ki	660.69	nM	10.1021/jm8003625
Homo sapiens	Alpha-2a adrenergic receptor	%Max (Mean)	5.0	%	10.6019/CHEMBL5209801
Homo sapiens	Alpha-2c adrenergic receptor	Ki	10.47	nM	10.1021/jm8003625
Homo sapiens	Alpha-2c adrenergic receptor	Ki	10.6	nM	10.1021/jm8003625
Homo sapiens	Apelin receptor	%Inhib (Mean)	3.85	%	10.6019/CHEMBL5209801
Homo sapiens	Apelin receptor	%Max (Mean)	1.224	%	10.6019/CHEMBL5209801
Homo sapiens	Arachidonate 15-lipoxygenase	Potency	31622.8	nM	None
Homo sapiens	Beta-2 adrenergic receptor	%Inhib (Mean)	-14.4	%	10.6019/CHEMBL5209801
Homo sapiens	Beta-2 adrenergic receptor	%Max (Mean)	-3.12	%	10.6019/CHEMBL5209801
Homo sapiens	Bromodomain-containing protein 4	Delta TM	-0.98	C	None
Homo sapiens	C5a anaphylatoxin chemotactic receptor	%Inhib (Mean)	-22.67	%	10.6019/CHEMBL5209801
Homo sapiens	C5a anaphylatoxin chemotactic receptor	%Max (Mean)	-3.908	%	10.6019/CHEMBL5209801
Homo sapiens	Casein kinase I delta	Delta TM	0.21	C	None
Homo sapiens	C-X3-C chemokine receptor 1	%Inhib (Mean)	-22.38	%	10.6019/CHEMBL5209801
Homo sapiens	C-X3-C chemokine receptor 1	%Max (Mean)	-2.156	%	10.6019/CHEMBL5209801
Homo sapiens	Cyclin-dependent kinase 2	Delta TM	0.15	C	None
Homo sapiens	DNA-(apurinic or apyrimidinic site) lyase	Potency	44668.4	nM	None
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	53.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	54.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	69.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	42.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	46.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	47.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	14985.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	15057.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	15078.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	15171.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	16285.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	16485.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	16657.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	17835.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Growth Rate	0.11	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.18	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.35	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.49	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.52	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Population Apoptotic (%)	27.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	29.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	37.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	43.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	47.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	64.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	27.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	29.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	33.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	37.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	39.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	48.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	49.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	73.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	33.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	52.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	59.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	70.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	93.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	94.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	95.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	96.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	97.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	98.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	99.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	27.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	46.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	58.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	95.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	101.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	102.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	104.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	106.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	108.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	110.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	121.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	155.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	168.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	174.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	175.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	178.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	189.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	190.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast growth factor receptor 3	Delta TM	0.24	C	None
Homo sapiens	Glucagon-like peptide 1 receptor	%Inhib (Mean)	-16.77	%	10.6019/CHEMBL5209801
Homo sapiens	Glucagon-like peptide 1 receptor	%Max (Mean)	0.22	%	10.6019/CHEMBL5209801
Homo sapiens	Glucose-dependent insulinotropic receptor	%Inhib (Mean)	-6.898	%	10.6019/CHEMBL5209801
Homo sapiens	Glucose-dependent insulinotropic receptor	%Max (Mean)	1.285	%	10.6019/CHEMBL5209801
Homo sapiens	Glycogen synthase kinase-3 beta	Delta TM	0.0	C	None
Homo sapiens	G-protein coupled receptor 120	%Inhib (Mean)	-43.0	%	10.6019/CHEMBL5209801
Homo sapiens	G-protein coupled receptor 120	%Max (Mean)	-1.2	%	10.6019/CHEMBL5209801
Homo sapiens	G-protein coupled receptor 35	%Inhib (Mean)	-44.94	%	10.6019/CHEMBL5209801
Homo sapiens	G-protein coupled receptor 35	%Max (Mean)	12.31	%	10.6019/CHEMBL5209801
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	46.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	81.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	82.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	59.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	83.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	75.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	77.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	22878.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	29842.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	35035.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	45150.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	45535.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	60692.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	68271.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	101135.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Growth Rate	0.67	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.74	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.82	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.85	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.91	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Population Apoptotic (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	27.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	47.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	48.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	59.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	78.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	81.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	82.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	83.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	85.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	39.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	43.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	58.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	73.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	78.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	84.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	43.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	52.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	64.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	69.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	73.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	75.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	84.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	86.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	90.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	91.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	93.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	94.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	95.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	97.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	29.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	42.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	58.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	239.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	241.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	273.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	295.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	356.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	384.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	400.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	419.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	474.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	484.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	514.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	572.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	618.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	630.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	735.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	767.0	None	10.6019/CHEMBL5058577
Homo sapiens	Histamine H1 receptor	Ki	10000.0	nM	10.1021/jm8003625
Homo sapiens	Histamine H2 receptor	Ki	10000.0	nM	10.1021/jm8003625
Homo sapiens	Histamine H3 receptor	Activity	45.0	%	10.1016/j.bmcl.2017.08.060
Homo sapiens	Histamine H3 receptor	Ki	3.467	nM	10.1021/jm8003625
Homo sapiens	Histamine H3 receptor	Ki	5.012	nM	10.1016/j.bmc.2008.07.071
Homo sapiens	Histamine H3 receptor	Ki	5.37	nM	10.1021/jm8003625
Homo sapiens	Histamine H3 receptor	Ki	5.37	nM	10.1021/jm900480x
Homo sapiens	Histamine H3 receptor	pKb	6.14	None	10.1021/jm8003625
Homo sapiens	Histamine H3 receptor	pKb	7.96	None	10.1021/jm8003625
Homo sapiens	Histamine H3 receptor	pKb	8.08	None	10.1021/jm8003625
Homo sapiens	Histamine H4 receptor	Ki	10000.0	nM	10.1021/jm8003625
Homo sapiens	Lipoxin A4 receptor	%Inhib (Mean)	-18.1	%	10.6019/CHEMBL5209801
Homo sapiens	Lipoxin A4 receptor	%Max (Mean)	-2.91	%	10.6019/CHEMBL5209801
Homo sapiens	MAP kinase ERK2	Delta TM	0.35	C	None
Homo sapiens	Peregrin	Delta TM	-3.04	C	None
Homo sapiens	Serine/threonine-protein kinase Aurora-A	Delta TM	0.08	C	None
Homo sapiens	Solute carrier organic anion transporter family member 1B1	Inhibition	100.94	%	10.1124/mol.112.084152
Homo sapiens	Solute carrier organic anion transporter family member 1B3	Inhibition	111.46	%	10.1124/mol.112.084152
Homo sapiens	Sphingosine 1-phosphate receptor Edg-1	%Inhib (Mean)	-1.6	%	10.6019/CHEMBL5209801
Homo sapiens	Sphingosine 1-phosphate receptor Edg-1	%Max (Mean)	-3.444	%	10.6019/CHEMBL5209801
Homo sapiens	Thyroid stimulating hormone receptor	Potency	2511.9	nM	None
Homo sapiens	Transcription intermediary factor 1-alpha	Delta TM	-1.7	C	None
Homo sapiens	Type-1 angiotensin II receptor	%Inhib (Mean)	-1.599	%	10.6019/CHEMBL5209801
Homo sapiens	Type-1 angiotensin II receptor	%Max (Mean)	-2.484	%	10.6019/CHEMBL5209801
Homo sapiens	Tyrosine-protein kinase ABL	Delta TM	0.1	C	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	16360.1	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	23715.0	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	29855.4	nM	None
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	33.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	71.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	74.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	76.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	8571.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	11828.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	14221.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	20657.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	20807.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	26450.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	31171.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	44507.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Growth Rate	0.8	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.89	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Population Apoptotic (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	58.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	75.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	83.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	85.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	86.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	89.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	90.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	100.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	31.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	57.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	70.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	71.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	73.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	74.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	81.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	93.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	95.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	96.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	97.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	98.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	99.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	100.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	81.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	91.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	107.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	124.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	134.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	153.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	175.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	193.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	198.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	227.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	237.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	248.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	265.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	307.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	370.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	430.0	None	10.6019/CHEMBL5058577
Leishmania amazonensis	Leishmania amazonensis	GI	97.0	%	10.1016/j.bmc.2008.05.074
Plasmodium falciparum	Plasmodium falciparum	IC50	1040.0	nM	10.1016/j.bmcl.2005.03.021
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)	MexAB/OprM	MIC	0.25	ug.mL-1	10.1021/acs.jmedchem.8b01781
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)	MexAB/OprM	MIC	2.0	ug.mL-1	10.1021/acs.jmedchem.8b01781
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)	MexAB/OprM	MIC	8.0	ug.mL-1	10.1021/acs.jmedchem.8b01781
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)	MexAB/OprM	MIC	32.0	ug.mL-1	10.1021/acs.jmedchem.8b01781
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)	MexAB/OprM	MIC	256.0	ug.mL-1	10.1021/acs.jmedchem.8b01781
Rattus norvegicus	Blood	Drug uptake	0.102	ug ml-1	10.1021/jm8003625
Rattus norvegicus	Blood	Drug uptake	0.306	ug ml-1	10.1021/jm8003625
Rattus norvegicus	Blood	Drug uptake	0.444	ug ml-1	10.1021/jm8003625
Rattus norvegicus	Brain	Drug uptake	4.14	ug/g	10.1021/jm8003625
Rattus norvegicus	Brain	Drug uptake	6.57	ug/g	10.1021/jm8003625
Rattus norvegicus	Brain	Drug uptake	6.8	ug/g	10.1021/jm8003625
Rattus norvegicus	Histamine H3 receptor	Activity	34.0	%	10.1016/j.bmcl.2017.08.060
Rattus norvegicus	Histamine H3 receptor	Ki	12.3	nM	10.1021/jm8003625
Rattus norvegicus	Histamine H3 receptor	Ki	24.5	nM	10.1021/jm8003625
Rattus norvegicus	Histamine H3 receptor	Ki	24.5	nM	10.1021/jm900480x
Rattus norvegicus	Histamine H3 receptor	Ki	24.55	nM	10.1021/jm8003625
Rattus norvegicus	Histamine H3 receptor	Ki	24.55	nM	10.1021/jm900480x
Rattus norvegicus	Histamine H3 receptor	Ki	66.0	nM	10.1016/j.bmcl.2007.12.059
Rattus norvegicus	Histamine H3 receptor	pKb	6.99	None	10.1021/jm8003625
Rattus norvegicus	Histamine H3 receptor	pKb	nan	None	10.1021/jm8003625
Rattus norvegicus	Inositol monophosphatase 1	Potency	7943.3	nM	None
Rattus norvegicus	Rattus norvegicus	Activity	nan	None	10.1021/jm8003625
Rattus norvegicus	Rattus norvegicus	Cp	0.037	ug ml-1	10.1021/jm8003625
Rattus norvegicus	Rattus norvegicus	Cp	0.089	ug ml-1	10.1021/jm8003625
Rattus norvegicus	Rattus norvegicus	Cp	0.148	ug ml-1	10.1021/jm8003625
Rattus norvegicus	Rattus norvegicus	Selectivity index	14.0	uM	10.1016/j.bmcl.2005.03.021
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	12000.0	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	12022.64	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	25100.0	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	25118.86	nM	10.6019/CHEMBL4651402
Trypanosoma cruzi	Trypanothione reductase	Inhibition	25.0	%	10.1016/j.bmc.2008.05.074
Trypanosoma cruzi	Trypanothione reductase	Inhibition	45.0	%	10.1016/j.bmc.2008.05.074
Trypanosoma cruzi	Trypanothione reductase	Inhibition	73.0	%	10.1016/j.bmc.2008.05.074
Trypanosoma cruzi	Trypanothione reductase	Inhibition	91.0	%	10.1016/j.bmc.2008.05.074
None	ADMET	Ratio	14.4	None	10.1021/jm8003625
None	ADMET	Ratio	46.0	None	10.1021/jm8003625
None	ADMET	Ratio	95.4	None	10.1021/jm8003625
None	ADMET	%Remaining	60.0	%	10.1021/jm900480x
None	NON-PROTEIN TARGET	IC50	14600.0	nM	10.1016/j.bmcl.2005.03.021
None	Unchecked	Ac50	3.548	uM	None
None	Unchecked	Ac50	10.0	uM	None
None	Unchecked	AC50	3548.1	nM	None
None	Unchecked	AC50	10000.0	nM	None
None	Unchecked	Activity	84.0	%	10.1016/j.bmcl.2017.08.060
None	Unchecked	Ki	2.0	nM	10.1021/jm8003625
None	Unchecked	Ki	1905.46	nM	10.1021/jm8003625
None	Unchecked	Ki	10000.0	nM	10.1021/jm8003625
None	Unchecked	Potency	3162.3	nM	None
None	Unchecked	Potency	11220.2	nM	None
None	Unchecked	Selectivity ratio	1860.0	None	10.1021/jm8003625