Navigation

name Structure Reference Source Properties Activities Metabolism

dimethyl(3-{tricyclo[9.4.0.0³,?]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine

AlkaPlorer ID: AK000746

Synonym: None

IUPAC Name: N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine

Structure

SMILES: CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12

copy

InChI: InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3

copy

InChIKey: KRMDCWKBEZIMAB-UHFFFAOYSA-N

copy

Reference

PubChem CID: 2160

NPASS: NPC330676

COCONUT: CNP0211765

Source

Species Genus Family Order Class Phylum Kingdom Domain
Euphorbia dulcis Euphorbia Euphorbiaceae Malpighiales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 277.411

TPSA？: 3.24

MolLogP？: 4.168600000000003

Number of H-Donors: 0

Number of H-Acceptors: 1

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Canis lupus familiaris Canis familiaris Dose 3.97 uM kg-1 10.1021/jm00185a024
Canis lupus familiaris Canis familiaris Dose 4.69 uM kg-1 10.1021/jm00185a024
Canis lupus familiaris Canis familiaris ED50 1.0 mg.kg-1 10.1021/jm00374a002
Canis lupus familiaris Canis familiaris ED50 1.1 mg.kg-1 10.1021/jm00374a002
Cavia porcellus Cavia porcellus IC50 0.0083 ug.mL-1 10.1021/jm00134a004
Cavia porcellus Histamine H2 receptor IC50 660.0 nM 10.1021/jm9910369
Cavia porcellus Histamine H2 receptor K0.5 0.5 nM 10.1021/jm980428x
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Cryptosporidium parvum Cryptosporidium parvum IC50 nan None 10.1016/j.bmc.2010.01.068
Entamoeba histolytica Entamoeba histolytica IC50 nan None 10.1016/j.bmc.2010.01.068
Homo sapiens Acetylcholinesterase AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 14085.4 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 26.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 29.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 120.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 105.0 nM None
Homo sapiens Alpha-1d adrenergic receptor Ki 52.0 nM None
Homo sapiens Alpha-2a adrenergic receptor AC50 1269.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 2919.5 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 9100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 351.0 nM None
Homo sapiens Alpha-2a adrenergic receptor Ki 132.0 nM None
Homo sapiens Alpha-2b adrenergic receptor AC50 280.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 8.076 nM None
Homo sapiens Alpha-2b adrenergic receptor Ki 3.687 nM None
Homo sapiens Alpha-2c adrenergic receptor AC50 290.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 59.0 nM None
Homo sapiens Alpha-2c adrenergic receptor Ki 8.599 nM None
Homo sapiens Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Arachidonate 15-lipoxygenase, type II Potency 15848.9 nM None
Homo sapiens Arachidonate 15-lipoxygenase, type II Potency 25118.9 nM None
Homo sapiens Ataxin-2 Potency 6309.6 nM None
Homo sapiens Ataxin-2 Potency 12589.3 nM None
Homo sapiens Ataxin-2 Potency 25118.9 nM None
Homo sapiens Beta-1 adrenergic receptor AC50 22700.2 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 21148.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump AC50 179999.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bile salt export pump IC50 135000.0 nM 10.1093/toxsci/kfq269
Homo sapiens Bradykinin B1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity 51.0 % 10.1021/jm7015683
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cerebroside-sulfatase Potency 3013.1 nM None
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Chromobox protein homolog 1 Potency 25118.9 nM None
Homo sapiens Corticotropin releasing factor receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 AC50 15848.93 nM None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 AC50 nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Inhibition 90.2 % 10.1016/j.bmcl.2022.128673
Homo sapiens Cytochrome P450 2C19 Inhibition 92.1 % 10.1016/j.bmc.2022.116862
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C19 Ratio IC50 2.0 None 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 AC50 nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 AC50 7943.28 nM None
Homo sapiens Cytochrome P450 2D6 AC50 39810.72 nM None
Homo sapiens Cytochrome P450 2D6 Activity nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2D6 Potency 7943.3 nM None
Homo sapiens Cytochrome P450 2D6 Potency 39810.7 nM None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 AC50 nan None None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Cytochrome P450 3A4 Log 1/Km -1.841 None 10.1016/j.bmcl.2005.06.015
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dopamine D1 receptor AC50 92.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 451.7 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 355.0 nM None
Homo sapiens Dopamine D1 receptor Ki 89.0 nM 10.1016/j.bmcl.2008.09.012
Homo sapiens Dopamine D1 receptor Ki 178.0 nM None
Homo sapiens Dopamine D1 receptor Potency 259.3 nM None
Homo sapiens Dopamine D1 receptor Potency 1122.0 nM None
Homo sapiens Dopamine D2 receptor AC50 550.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 1009.0 nM None
Homo sapiens Dopamine D2 receptor Ki 196.0 nM 10.1016/j.bmcl.2008.09.012
Homo sapiens Dopamine D2 receptor Ki 336.0 nM None
Homo sapiens Dopamine D3 receptor AC50 146.7 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor AC50 440.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 182.0 nM None
Homo sapiens Dopamine D3 receptor Ki 62.0 nM None
Homo sapiens Dopamine D3 receptor Ki 206.0 nM 10.1016/j.bmcl.2008.09.012
Homo sapiens Dopamine D4 receptor AC50 818.7 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine D5 receptor Ki 170.0 nM 10.1016/j.bmcl.2008.09.012
Homo sapiens Dopamine transporter AC50 7417.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 13773.7 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 12589.25 nM 10.1016/j.bmcl.2013.03.066
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki 6203.0 nM 10.1016/j.bmcl.2013.03.066
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Potency 7943.3 nM None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Endothelin receptor ET-B AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Gastric inhibitory polypeptide receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucagon receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens HEK293 Potency 9196.2 nM None
Homo sapiens HepG2 IC50 29600.0 nM 10.1016/j.ejmech.2020.112395
Homo sapiens HERG AC50 5496.2 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 1810.0 nM 10.1021/acs.jmedchem.1c02071
Homo sapiens HERG IC50 3000.0 nM 10.1021/acs.jmedchem.8b01300
Homo sapiens HERG IC50 3200.0 nM 10.1021/acs.jmedchem.2c01497
Homo sapiens HERG IC50 3280.0 nM 10.1093/cvr/cvr044
Homo sapiens HERG IC50 3290.0 nM 10.1016/j.bmcl.2017.12.068
Homo sapiens HERG IC50 9600.0 nM 10.1016/j.ejmech.2018.12.042
Homo sapiens HERG IC50 10000.0 nM 10.1016/j.bmc.2008.04.028
Homo sapiens HERG IC50 10000.0 nM 10.1016/j.bmcl.2005.01.008
Homo sapiens HERG IC50 10000.0 nM 10.1016/j.bmcl.2005.03.080
Homo sapiens HERG IC50 10000.0 nM 10.1016/j.ejmech.2008.11.009
Homo sapiens HERG IC50 10000.0 nM 10.1016/j.ejmech.2010.11.042
Homo sapiens HERG IC50 10000.0 nM 10.1016/s0960-894x(03)00492-x
Homo sapiens HERG IC50 10000.0 nM 10.1021/jm0208875
Homo sapiens HERG IC50 17589.4 nM None
Homo sapiens HERG Inhibition 23.15 % 10.1021/acs.jmedchem.1c01022
Homo sapiens HERG Inhibition 76.13 % 10.1021/acs.jmedchem.1c01022
Homo sapiens HERG Inhibition 97.7 % 10.1021/acs.jnatprod.8b00500
Homo sapiens HERG Ki 14410.6 nM None
Homo sapiens Histamine H1 receptor AC50 13.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 4.782 nM None
Homo sapiens Histamine H1 receptor Inhibition 99.0 % 10.1021/acs.jmedchem.1c00497
Homo sapiens Histamine H1 receptor Ki 0.555 nM None
Homo sapiens Histamine H1 receptor Ki 1.12 nM 10.1016/j.bmcl.2008.09.012
Homo sapiens Histamine H2 receptor AC50 21.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 730.0 nM None
Homo sapiens Histamine H2 receptor Ki 718.0 nM None
Homo sapiens Histamine H3 receptor AC50 23999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor Ki 1000.0 nM 10.1016/j.bmcl.2008.09.012
Homo sapiens Histone deacetylase 6 Inhibition 14.67 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition 60.37 % 10.6019/CHEMBL4808148
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens CL 6.0 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 6.1 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 6.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.12 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 5.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens Fa 0.95 None 10.1021/jm901371v
Homo sapiens Homo sapiens F_fraction 0.48 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.68 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.74 None 10.1021/jm901371v
Homo sapiens Homo sapiens Vdss 8.3 L.kg-1 10.1016/j.ejmech.2009.06.004
Homo sapiens Homo sapiens Vdss 8.7 L.kg-1 10.1021/jm901371v
Homo sapiens Hydroxycarboxylic acid receptor 2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor AC50 1101.6 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens Liver microsomes Activity nan None 10.1021/tx300075j
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 23000.1 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 17656.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 9461.7 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 49.1 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 610.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 11.0 nM None
Homo sapiens Muscarinic acetylcholine receptor M1 Inhibition 78.0 % 10.1021/acs.jmedchem.1c00497
Homo sapiens Muscarinic acetylcholine receptor M1 Ki 2.724 nM None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 40.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 91.8 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 188.8 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 1100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 81.0 nM None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki 29.0 nM None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 260.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 26.0 nM None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki 5.436 nM None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 5.297 nM None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki 0.739 nM None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 8.02 nM None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki 5.762 nM None
Homo sapiens NCI-H1650 GI50 40000.0 nM 10.1016/j.bmc.2015.07.007
Homo sapiens Nerve growth factor receptor Trk-A EC50 86000.0 nM 10.1021/jm501307e
Homo sapiens Nerve growth factor receptor Trk-A IC50 60000.0 nM 10.1021/jm501307e
Homo sapiens Nerve growth factor receptor Trk-A Kd 1800000.0 nM 10.1021/jm501307e
Homo sapiens Nerve growth factor receptor Trk-A Kd 2100000.0 nM 10.1021/jm501307e
Homo sapiens Nerve growth factor receptor Trk-A Kd 2200000.0 nM 10.1021/jm501307e
Homo sapiens Neurokinin 1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Neurotensin receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter AC50 37.6 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter AC50 440.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 23.0 nM None
Homo sapiens Norepinephrine transporter IC50 2041.74 nM 10.1016/j.bmcl.2013.03.066
Homo sapiens Norepinephrine transporter Ki 22.0 nM None
Homo sapiens Norepinephrine transporter Ki 333.0 nM 10.1016/j.bmcl.2013.03.066
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 1933.1 nM None
Homo sapiens Nuclear factor NF-kappa-B p105 subunit Potency 5011.9 nM None
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/s0378-5173(03)00372-7
Homo sapiens P-glycoprotein 1 Activity nan None 10.1124/jpet.102.039255
Homo sapiens P-glycoprotein 1 Inhibition 25.5 % 10.1124/jpet.102.039255
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Plasma K(p,uu,CSF) 0.18 None 10.1021/jm901036q
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine-protein kinase mTOR Potency 14689.2 nM None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 337.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 3768.3 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 6100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 29.8 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 920.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 15.0 nM None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki 4.374 nM None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 82.6 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 1100.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 70.0 nM None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki 45.0 nM None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 150.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 6.048 nM None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki 3.168 nM None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 8700.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 140.0 nM None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki 65.0 nM None
Homo sapiens Serotonin transporter AC50 7.6 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 9.5 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 1.661 nM None
Homo sapiens Serotonin transporter IC50 549.54 nM 10.1016/j.bmcl.2013.03.066
Homo sapiens Serotonin transporter Inhibition 50.0 % 10.1021/acs.jmedchem.6b00571
Homo sapiens Serotonin transporter Ki 0.882 nM None
Homo sapiens Serotonin transporter Ki 4.3 nM 10.1016/j.bmcl.2013.12.024
Homo sapiens Serotonin transporter Ki 5.4 nM 10.1021/acs.jmedchem.6b00571
Homo sapiens Serotonin transporter Ki 9.2 nM 10.1016/j.bmc.2021.116509
Homo sapiens Serotonin transporter Ki 9.55 nM 10.1016/j.bmcl.2013.12.024
Homo sapiens Serotonin transporter Ki 141.0 nM 10.1016/j.bmcl.2013.03.066
Homo sapiens SH-SY5Y IC50 48100.0 nM 10.1016/j.ejmech.2020.112395
Homo sapiens SH-SY5Y Potency 25118.9 nM None
Homo sapiens Sigma opioid receptor IC50 1031.0 nM None
Homo sapiens Sigma opioid receptor Ki 433.0 nM None
Homo sapiens Sodium channel alpha subunit IC50 20000.0 nM 10.1093/cvr/cvr044
Homo sapiens Sodium channel alpha subunits; brain (Types I, II, III) IC50 10000.0 nM 10.1021/jm00381a019
Homo sapiens Sodium channel alpha subunits; brain (Types I, II, III) Inhibition 73.8 % 10.1021/jm00381a019
Homo sapiens Sodium channel protein type II alpha subunit IC50 3100.0 nM 10.1021/jm300623u
Homo sapiens Sodium channel protein type IX alpha subunit IC50 1000.0 nM 10.1021/jm300623u
Homo sapiens Sodium channel protein type IX alpha subunit IC50 7000.0 nM 10.1021/jm300623u
Homo sapiens Sodium channel protein type V alpha subunit AC50 1810.6 nM 10.1038/s41467-023-40064-9
Homo sapiens Sodium channel protein type V alpha subunit IC50 1600.0 nM 10.1021/jm300623u
Homo sapiens Solute carrier family 22 member 1 IC50 16900.0 nM 10.1021/jm8003152
Homo sapiens Solute carrier family 22 member 1 Inhibition 78.5 % 10.1021/jm8003152
Homo sapiens Solute carrier family 22 member 3 Inhibition 80.0 % 10.1021/acs.jmedchem.2c01075
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 10.5 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 22.0 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Inhibition -8.9 % 10.1021/jm300212s
Homo sapiens Sphingomyelin phosphodiesterase Activity 11.7 % 10.1021/jm070524a
Homo sapiens Thrombin AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane A2 receptor AC50 26338.4 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 1400.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Tyrosine-protein kinase receptor RET IC50 1000.0 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 39810.7 nM None
Homo sapiens UDP-glucuronosyltransferase 1-1 Activity 0.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1-10 Activity 0.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1-3 Activity 38.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1-3 Km 267000.0 nM 10.1016/j.pharmthera.2004.10.013
Homo sapiens UDP-glucuronosyltransferase 1-3 Vmax 55.0 pmol/min/mg protein 10.1016/j.pharmthera.2004.10.013
Homo sapiens UDP-glucuronosyltransferase 1-6 Activity 0.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1-7 Activity 0.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1-9 Activity 0.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1A4 Activity 97.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1A4 Activity 98.0 pm/min/mg 10.1146/annurev.pharmtox.40.1.581
Homo sapiens UDP-glucuronosyltransferase 1A4 Activity nan None None
Homo sapiens UDP-glucuronosyltransferase 1A4 Km 60000.0 nM 10.1021/jm020397c
Homo sapiens UDP-glucuronosyltransferase 1A4 Km 100000.0 nM 10.1016/j.pharmthera.2004.10.013
Homo sapiens UDP-glucuronosyltransferase 1A4 Km 170000.0 nM 10.1016/j.pharmthera.2004.10.013
Homo sapiens UDP-glucuronosyltransferase 1A4 Vmax 96.0 pmol/min/mg protein 10.1016/j.pharmthera.2004.10.013
Homo sapiens UDP-glucuronosyltransferase 1A4 Vmax 340.0 pmol/min/mg protein 10.1016/j.pharmthera.2004.10.013
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel IC50 11600.0 nM 10.1093/cvr/cvr044
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit AC50 32000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated N-type calcium channel alpha-1B subunit IC50 12000.0 nM 10.1039/d1md00331c
Homo sapiens Whole blood Retention_time 5.86 min 10.1007/s00044-012-9977-1
Leishmania amazonensis Leishmania amazonensis IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania donovani Leishmania donovani IC50 10810.0 nM 10.6019/CHEMBL3392926
Leishmania donovani Leishmania donovani IC50 131250.0 nM 10.6019/CHEMBL3392926
Leishmania donovani Leishmania donovani IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania infantum Leishmania infantum IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania major Leishmania major IC50 nan None 10.1016/j.bmc.2010.01.068
Leishmania mexicana Leishmania mexicana IC50 nan None 10.1016/j.bmc.2010.01.068
Mus musculus Mus musculus Activity nan None 10.1016/j.ejmech.2019.05.026
Mus musculus Mus musculus ED50 0.36 mg.kg-1 10.1021/jm00401a031
Mus musculus Mus musculus ED50 1.3 mg.kg-1 10.1021/jm00346a003
Mus musculus Mus musculus ED50 1.3 mg.kg-1 10.1021/jm00374a002
Mus musculus Mus musculus ED50 1.4 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus ED50 1.5 mg.kg-1 10.1021/jm00133a016
Mus musculus Mus musculus ED50 1.5 mg.kg-1 10.1021/jm00137a025
Mus musculus Mus musculus ED50 1.5 mg.kg-1 10.1021/jm00346a003
Mus musculus Mus musculus ED50 1.5 mg.kg-1 10.1021/jm00361a009
Mus musculus Mus musculus ED50 1.5 mg.kg-1 10.1021/jm950644v
Mus musculus Mus musculus ED50 1.9 mg.kg-1 10.1021/jm00197a013
Mus musculus Mus musculus ED50 1.9 mg.kg-1 10.1021/jm00346a003
Mus musculus Mus musculus ED50 1.9 mg.kg-1 10.1021/jm00346a004
Mus musculus Mus musculus ED50 1.94 mg.kg-1 10.1021/jm00361a009
Mus musculus Mus musculus ED50 2.9 uM 10.1021/jm00145a005
Mus musculus Mus musculus ED50 3.5 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus ED50 4.4 mg.kg-1 10.1021/jm00371a011
Mus musculus Mus musculus ED50 4.4 mg.kg-1 10.1021/jm00383a002
Mus musculus Mus musculus ED50 4.7 mg.kg-1 10.1021/jm00228a011
Mus musculus Mus musculus ED50 5.0 mg.kg-1 10.1021/jm00346a003
Mus musculus Mus musculus ED50 5.4 uM 10.1021/jm00145a005
Mus musculus Mus musculus ED50 7.8 mg.kg-1 10.1021/jm00133a016
Mus musculus Mus musculus ED50 8.0 mg.kg-1 10.1021/jm00346a003
Mus musculus Mus musculus ED50 8.0 mg.kg-1 10.1021/jm00361a009
Mus musculus Mus musculus ED50 8.0 mg.kg-1 10.1021/jm00371a011
Mus musculus Mus musculus ED50 8.73 mg.kg-1 10.1021/jm00401a031
Mus musculus Mus musculus ED50 9.6 mg.kg-1 10.1021/jm00346a003
Mus musculus Mus musculus ED50 14.0 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus ED50 14.0 mg.kg-1 10.1021/jm00371a011
Mus musculus Mus musculus ED50 21.0 mg.kg-1 10.1021/jm00374a002
Mus musculus Mus musculus ED50 23.0 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus ED50 27.0 mg.kg-1 10.1021/jm00374a002
Mus musculus Mus musculus ED50 35.0 mg.kg-1 10.1021/jm00134a004
Mus musculus Mus musculus ED50 40.0 mg.kg-1 10.1021/jm00134a004
Mus musculus Mus musculus ED50 43.0 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus ED50 114.0 umol.kg-1 10.1021/jm00400a005
Mus musculus Mus musculus ED50 144.0 umol.kg-1 10.1021/jm00145a005
Mus musculus Mus musculus ED50 190.0 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus ED50 324.0 mg.kg-1 10.1021/jm00135a018
Mus musculus Mus musculus HYPO 0.5 mg kg-1 10.1021/jm00371a011
Mus musculus Mus musculus IC50 2900.0 nM 10.1021/jm00400a005
Mus musculus Mus musculus IC50 5400.0 nM 10.1021/jm00400a005
Mus musculus Mus musculus LD50 70.0 mg.kg-1 10.1021/jm00371a011
Mus musculus Mus musculus LD50 94.0 mg.kg-1 10.1021/jm00228a011
Mus musculus Mus musculus LD50 100.0 mg.kg-1 10.1021/jm00401a031
Mus musculus Mus musculus LD50 300.0 mg.kg-1 10.1021/jm00134a004
Mus musculus Mus musculus Lethality 37.0 % 10.1021/jm00108a018
Mus musculus Mus musculus Min oral dose 0.15 mg kg-1 10.1021/jm00383a002
Mus musculus Mus musculus Mouse behavior activity nan None 10.1021/jm00371a011
Mus musculus Mus musculus Relative potency 5.8 None 10.1021/jm00134a004
Mus musculus Mus musculus Reserpine hypothermia 0.15 None 10.1021/jm00371a011
Mus musculus NIH3T3 Activity nan None 10.1016/j.ejmech.2018.03.065
Mus musculus NIH3T3 Activity nan None 10.1021/acs.jmedchem.9b00739
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus P-glycoprotein 3 Activity nan None 10.1016/s0893-133x(99)00095-0
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.bmc.2017.10.004
Plasmodium falciparum Plasmodium falciparum IC50 1160.0 nM 10.6019/CHEMBL3392926
Plasmodium falciparum Plasmodium falciparum IC50 558000.0 nM 10.1016/j.bmc.2010.01.068
Pneumocystis carinii Pneumocystis carinii IC50 nan None 10.1016/j.bmc.2010.01.068
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 0.02 nM 10.1021/jm9910369
Rattus norvegicus Alpha-1a adrenergic receptor IC50 14.0 nM None
Rattus norvegicus Alpha-1a adrenergic receptor Inhibition 82.0 % 10.1021/acs.jmedchem.1c00497
Rattus norvegicus Alpha-1a adrenergic receptor Ki 5.599 nM None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 76.0 nM None
Rattus norvegicus Alpha-1b adrenergic receptor Ki 42.0 nM None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Brain Fu 0.009 None 10.1124/dmd.110.036095
Rattus norvegicus Brain Fu 0.01 None 10.1124/dmd.110.035998
Rattus norvegicus Brain Kp 3.08 None 10.1124/dmd.110.035998
Rattus norvegicus Brain Vd 310.0 L.kg-1 10.1124/dmd.110.035998
Rattus norvegicus Brain Vdu 310.0 ml 10.1021/jm901036q
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Histamine H1 receptor IC50 0.02 nM 10.1021/jm9910369
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Monoamine oxidase ED50 135.0 mg.kg-1 10.1021/jm00374a002
Rattus norvegicus Monoamine oxidase KI50 0.001 M l-1 10.1021/jm00374a002
Rattus norvegicus Muscarinic acetylcholine receptor IC50 300.0 nM 10.1021/jm950644v
Rattus norvegicus Muscarinic acetylcholine receptor M1 Potency 125.9 nM None
Rattus norvegicus Muscarinic acetylcholine receptor M1 Potency 223.9 nM None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Norepinephrine transporter IC50 2500.0 nM 10.1021/jm00371a011
Rattus norvegicus Plasma Cp(f) 0.022 uM 10.1021/jm901036q
Rattus norvegicus Plasma Fu 0.07 None 10.1021/jm901371v
Rattus norvegicus Plasma Fu 0.09 None 10.1021/jm901036q
Rattus norvegicus Plasma K(p,uu,CSF) 0.17 None 10.1021/jm901036q
Rattus norvegicus Plasma logFu 0.06 None 10.1016/j.ejmech.2009.06.004
Rattus norvegicus Rattus norvegicus Activity nan None 10.1021/acs.jmedchem.9b00739
Rattus norvegicus Rattus norvegicus ALB 24000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 25000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 26000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 27000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 28000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 29000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALB 40000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALBGLOB 0.8 None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALBGLOB 0.9 None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 355.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 363.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 377.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 394.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 416.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 422.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 1098.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1151.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1309.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1334.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1354.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1395.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1397.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1444.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1452.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1482.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1505.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1508.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1527.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1528.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1530.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1536.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1542.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1549.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1561.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1572.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1573.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1574.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1627.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1628.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1690.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1692.3 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1703.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1755.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1784.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1812.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1844.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALP 1976.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 36.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 39.7 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 39.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 40.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 40.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 41.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 42.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 42.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 43.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 43.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 44.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 44.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 44.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 45.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 46.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 47.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 47.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 47.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 48.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 49.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 49.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 49.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 50.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 52.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 53.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 53.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 54.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 54.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 55.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 55.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 60.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 62.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus ALT 66.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus APTT 14.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 15.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 15.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 15.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 15.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.4 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 16.7 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 17.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 17.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 18.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 20.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 21.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus APTT 22.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 57.7 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 59.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 61.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 61.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 63.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 64.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 67.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 68.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 69.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 69.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 70.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 71.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 71.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 71.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 72.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 73.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 74.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 74.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 74.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 76.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 77.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 77.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 78.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 79.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 80.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 80.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 83.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus AST 87.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 89.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 92.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 96.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 106.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BASOLE 0.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.04 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.06 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.08 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.1 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.12 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.14 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.16 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.167 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.18 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.2 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.22 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILDIR 0.24 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.42 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.46 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.467 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.48 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.5 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.52 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.54 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.56 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.58 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.6 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.62 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 0.7 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 68.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 70.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 74.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 78.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 80.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 84.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 86.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 88.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 100.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 126.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 138.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 140.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 140.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 142.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 144.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 146.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 147.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 154.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 158.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 160.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 164.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 168.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 170.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 172.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 176.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus BUN 184.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 103.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 105.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 106.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 107.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 108.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 109.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 110.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 111.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CALCIUM 112.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHLORIDE 99.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 103.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 563.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 620.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 666.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 673.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 676.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 690.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 700.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 714.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 716.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 721.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 726.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 762.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 770.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 772.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 774.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 780.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 784.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 786.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 788.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 792.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 794.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 802.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 804.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 808.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 812.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 826.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 830.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 832.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 844.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 856.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 870.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 942.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CHOL 970.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CK 268.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 464.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 466.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 486.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 601.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 1225.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Cl 103.7 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 103.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 104.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 104.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 104.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 104.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.4 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 105.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.4 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.6 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 106.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 107.0 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 107.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 107.4 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 107.8 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Cl 108.2 meq/L 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CO2 30000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 30330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 31330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 31830000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 33830000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 34000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CREAT 1.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus CREAT 2.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ED50 7.1 mg.kg-1 10.1021/jm00133a016
Rattus norvegicus Rattus norvegicus ED50 7.1 mg.kg-1 10.1021/jm00137a025
Rattus norvegicus Rattus norvegicus ED50 7.1 mg.kg-1 10.1021/jm00346a003
Rattus norvegicus Rattus norvegicus ED50 7.1 mg.kg-1 10.1021/jm00361a009
Rattus norvegicus Rattus norvegicus ED50 12.0 mg.kg-1 10.1021/jm00374a002
Rattus norvegicus Rattus norvegicus ED50 22.6 mg.kg-1 10.1021/jm00361a009
Rattus norvegicus Rattus norvegicus ED50 37.0 mg.kg-1 10.1021/jm00228a011
Rattus norvegicus Rattus norvegicus Effect 31.0 % 10.1021/jm00134a004
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 19.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 42.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 43.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 58.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 85.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 1.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 1.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus EOSLE 1.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2356.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2530.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2562.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2592.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2626.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2660.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2674.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2680.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2686.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2730.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2738.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2774.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2792.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2806.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2826.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2830.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2856.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2866.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2874.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2886.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2896.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2920.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2944.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2956.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 2990.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3026.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3058.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3113.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 3266.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus FIBRINO 4134.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 0.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 0.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 0.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 0.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 0.7 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 0.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GGT 1.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1373.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1453.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1516.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1525.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1545.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1642.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1652.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1692.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1702.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1736.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1740.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1744.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1748.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1758.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1792.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1794.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1796.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1806.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1816.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1826.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1836.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1852.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1858.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1864.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1866.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1870.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1876.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1880.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1880.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1918.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1928.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1934.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1960.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus GLUC 1986.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 35.77 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.93 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.88 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.63 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 38.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 39.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 40.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 41.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 42.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 43.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 43.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 43.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 44.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 45.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 45.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 45.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HCT 46.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 125000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 127000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 128000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 130000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 131000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 132000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 133000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 134000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 135000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 136000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 138000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 140000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 142000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 142800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 143300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 144000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 144800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 145000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 149000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 150000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 153000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 153300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 155000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 156000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus HGB 158000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus IC50 61.0 nM 10.1021/jm00400a005
Rattus norvegicus Rattus norvegicus IC50 320.0 nM 10.1021/jm00400a005
Rattus norvegicus Rattus norvegicus IC50 2000.0 nM 10.1021/jm00346a003
Rattus norvegicus Rattus norvegicus IC50 2000.0 nM 10.1021/jm00361a009
Rattus norvegicus Rattus norvegicus IC50 2500.0 nM 10.1021/jm00383a002
Rattus norvegicus Rattus norvegicus IC50 4700.0 nM 10.1021/jm00346a003
Rattus norvegicus Rattus norvegicus IC50 4700.0 nM 10.1021/jm00361a009
Rattus norvegicus Rattus norvegicus IC50 12000.0 nM 10.1021/jm00383a002
Rattus norvegicus Rattus norvegicus IC50 14000.0 nM 10.1021/jm00346a003
Rattus norvegicus Rattus norvegicus IC50 14000.0 nM 10.1021/jm00361a009
Rattus norvegicus Rattus norvegicus LDH 50.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 51.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 55.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 56.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 57.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 58.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 58.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 60.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 62.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 62.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 62.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 65.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 65.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 66.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 66.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 67.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 68.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 69.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 70.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 72.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 72.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 74.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 74.6 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 81.0 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 82.4 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 83.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 85.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 86.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 90.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 90.8 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 116.2 IU.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LDH 162.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 212.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 246.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 301.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 318.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 605.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 12.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Log 1/ED50 1.85 None 10.1021/jm00135a006
Rattus norvegicus Rattus norvegicus LYM 10052.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11823.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11980.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12245.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12577.83 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 16571.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 65.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 67.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 70.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 71.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 72.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 73.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 74.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 74.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 75.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 76.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 76.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 76.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 77.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 77.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 77.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 77.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 78.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 79.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 79.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 80.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 80.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 80.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 81.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 82.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus LYMLE 88.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 92.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 94.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 94.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 19.1 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 19.3 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 19.6 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 19.7 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.0 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.2 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.3 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.5 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.6 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.7 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.8 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 20.9 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.0 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.1 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.2 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.3 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.5 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 21.6 pg 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCH 24.37 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.85 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.93 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.83 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.92 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.93 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 32.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 32.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 33.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 34.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCHC 391700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 393000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 397000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 399000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 399500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 399700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 55.9 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 56.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 56.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 57.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 58.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 60.3 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 60.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 61.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 61.8 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.0 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.27 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.43 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 62.8 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.1 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.23 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.3 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 63.9 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.4 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.6 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.7 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.8 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 64.85 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.87 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 65.0 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 65.1 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 65.13 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 65.4 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 65.5 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MCV 65.8 fL 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONO 40.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 70.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 106.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 111.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 169.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 212.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 2.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus MONOLE 3.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 4.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 14.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 14.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 14.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 14.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 15.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 16.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 16.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 17.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 17.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 17.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 18.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 18.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 18.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 19.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 19.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 20.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 20.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 21.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 22.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 22.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 22.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 23.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 23.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 24.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 29.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTLE 30.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus NEUTSG 435.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 697.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 815.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 896.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1045.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1432.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus No. of escape failures 1.2 None 10.1021/jm001059j
Rattus norvegicus Rattus norvegicus No. of escape failures 3.3 None 10.1021/jm001059j
Rattus norvegicus Rattus norvegicus No. of escape failures 9.0 None 10.1021/jm001059j
Rattus norvegicus Rattus norvegicus Papp 2.3 None 10.1021/jm00135a006
Rattus norvegicus Rattus norvegicus PHOS 62.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 63.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 68.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 71.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 72.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 73.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 75.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 76.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 77.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 78.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 79.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 80.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 82.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 87.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 88.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 92.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 93.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 98.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 99.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 100.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 104.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 107.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOS 113.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 116.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 117.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 120.8 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 124.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 129.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOSLPD 977.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1244.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1330.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1350.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1380.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1382.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1388.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1398.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1404.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1420.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1426.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1432.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1434.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1444.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1446.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1468.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1496.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1502.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1530.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1538.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1540.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1558.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1562.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1564.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1570.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1584.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1622.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1638.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PHOSLPD 1658.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 975000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 979000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1015000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1039000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1041000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1084000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1088000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1099000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1100000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1107000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1110000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1127000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1141000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1165000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1167000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1171000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1174000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1177000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1179000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1181000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1188000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1191000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1198000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1200000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1201000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1206000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1222000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1223500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1236000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1237000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1246170.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1249670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1250000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1258000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1279000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1286000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PLAT 1316670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1403330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 3.7 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 3.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 3.9 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.0 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.1 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.3 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 4.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus POTASSIUM 5.4 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.61 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.12 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.47 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.68 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.73 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 53000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 54000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 55000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 56000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 58000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 59000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 59300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 60300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 61000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 62000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PROT 62300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 63000.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.5 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.7 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.8 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 15.9 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.1 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.2 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.3 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.4 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 16.6 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus PT 17.0 s 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 5520000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5600000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5760000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5820000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5840000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5894000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 5924000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 5930000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5970000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6048000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6102000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6118000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6134000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6158000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6166000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6178000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6188000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6252000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6262000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6292000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6294000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6346000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6380000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6414000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6454000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6488000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6496000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6590000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6644000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 6986000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7050000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7136000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7408000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7608000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7634000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 7972000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 8028000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBC 8243000.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.33 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RETIRBC 2.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 2.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 3.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 4.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 5.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 5.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.0 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 6.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 7.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 7.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.6 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.7 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.8 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 8.9 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 9.1 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 9.2 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 9.3 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 9.4 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus RETIRBC 9.5 % 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 141.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 141.6 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 142.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 142.43 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 142.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.0 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.4 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.4 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 143.8 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 144.2 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 145.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.53 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.6 mEq.L-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus SODIUM 145.83 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus TERMBW 188.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 191.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 191.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 191.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 192.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 193.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 193.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 193.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 194.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 194.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 194.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 200.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 205.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 206.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 206.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 208.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 221.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 224.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 226.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 250.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 255.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 259.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 265.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 303.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 305.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 314.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 318.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 359.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 400.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TERMBW 406.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus TRIG 288.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 296.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 332.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 348.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 353.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 406.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 422.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 428.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 438.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 440.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 444.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 478.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 498.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 520.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 628.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 670.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 822.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 930.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 974.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 978.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 988.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1060.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1080.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1140.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1218.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1260.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1288.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1304.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1312.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1348.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1452.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus TRIG 1562.0 ug.mL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus URATE 15.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 15.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 17.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 18.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 18.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 6600.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7010.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7130.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7160.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7180.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7500.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 7910.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8450.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8630.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8720.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8780.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8930.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 8940.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9060.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9140.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9360.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9450.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9780.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 9930.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10140.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10190.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10210.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10470.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10490.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 10600.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 10780.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 11520.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 11980.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 12050.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 12810.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 12870.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13070.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13420.0 cells.uL-1 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WBC 13600.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13830.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 17570.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WEIGHT 0.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 0.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 1.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.3 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 2.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 7.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 7.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 7.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 7.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 7.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 8.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.5 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 9.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 10.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 10.4 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 10.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 11.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 11.9 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 12.6 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 12.7 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 12.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 13.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 14.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 14.2 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 16.1 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 16.8 g 10.6019/CHEMBL3885861
Rattus norvegicus Rattus norvegicus WEIGHT 17.0 g 10.6019/CHEMBL3885861
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 1996.0 nM None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki 1141.0 nM None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 3730.0 nM None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki 1695.0 nM None
Rattus norvegicus Serotonin (5-HT) receptor IC50 44.0 nM 10.1021/jm9910369
Rattus norvegicus Serotonin transporter IC50 8500.0 nM 10.1021/jm00371a011
Rattus norvegicus Serum albumin Kd 134000.0 nM 10.1124/dmd.110.036095
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 28183.8 nM None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit IC50 3750.0 nM 10.1002/jat.2784
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit IC50 23200.0 nM 10.1002/jat.2784
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Toxoplasma gondii Toxoplasma gondii IC50 nan None 10.1016/j.bmc.2010.01.068
Trichomonas vaginalis Trichomonas vaginalis IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma brucei Trypanosoma brucei IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 3030.0 nM 10.6019/CHEMBL3392926
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 nan None 10.1016/j.bmc.2010.01.068
Trypanosoma cruzi Trypanosoma cruzi EC50 12000.0 nM 10.1128/aac.01777-09
Trypanosoma cruzi Trypanosoma cruzi IC50 35110.0 nM 10.6019/CHEMBL3392926
Trypanosoma cruzi Trypanosoma cruzi IC50 nan None 10.1016/j.bmc.2010.01.068
None ADMET Binding energy 12.3 kCal mol-1 10.1021/jm00378a021
None ADMET BPR 20.15 None 10.1021/jm901036q
None ADMET CL 6.1 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CLm 72.0 l hr-1 10.1021/jm9910369
None ADMET delta logD -0.9 None 10.1021/jm0000564
None ADMET EC50 23000.0 nM 10.1128/aac.01777-09
None ADMET EFTPC 26.0 nM 10.1093/cvr/cvr044
None ADMET F 49.0 % 10.1021/jm0000564
None ADMET Fu 0.06 None 10.1021/jm030408h
None ADMET Kd 1010.0 nM 10.1124/dmd.110.036095
None ADMET K(p,uu,brain) 0.73 None 10.1021/jm901036q
None ADMET LD50 177.0 mg.kg-1 10.1021/jm00374a002
None ADMET Log k' 0.753 None 10.1021/jm00135a006
None ADMET Log k' 1.214 None 10.1021/jm00135a006
None ADMET Log k' 1.264 None 10.1021/jm00135a006
None ADMET Log k' 1.279 None 10.1021/jm00135a006
None ADMET Log k' 1.419 None 10.1021/jm00135a006
None ADMET Log k' 1.641 None 10.1021/jm00135a006
None ADMET Log K 1.84 None 10.1021/jm9910369
None ADMET MRT 24.0 hr 10.1124/dmd.108.020479
None ADMET pKa 9.42 None 10.1021/jm9910369
None ADMET Ratio 0.98 None 10.1021/jm701549s
None ADMET Ratio 1.0 None 10.1124/dmd.110.036095
None ADMET Ratio 1.2 None 10.1124/dmd.110.036095
None ADMET Ratio 9.6 None 10.1021/jm960163r
None ADMET T1/2 17.0 hr 10.1124/dmd.108.020479
None ADMET T1/2 27.5 hr 10.1021/jm9910369
None ADMET T.P.L 180.0 ng ml-1 10.1021/jm9910369
None ADMET Vd 15.0 L.kg-1 10.1021/jm9910369
None ADMET Vdss 8.3 L.kg-1 10.1021/jm030408h
None ADMET Vdss 8.7 L.kg-1 10.1124/dmd.108.020479
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 3.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports nan None 10.2174/1570163043334794
None Molecular identity unknown Fu 0.0071 None 10.1124/dmd.110.036095
None Molecular identity unknown Fu 0.0073 None 10.1124/dmd.110.036095
None Molecular identity unknown Fu 0.0083 None 10.1124/dmd.110.036095
None NON-PROTEIN TARGET Fu 0.07 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 3.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 11.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 26.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 36050.0 nM 10.6019/CHEMBL3392926
None NON-PROTEIN TARGET IC50 42180.0 nM 10.6019/CHEMBL3392926
None NON-PROTEIN TARGET IC50 nan None 10.1016/j.bmc.2010.01.068
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.00661-08
None NON-PROTEIN TARGET MIC 512.0 ug.mL-1 10.1128/aac.00661-08
None NON-PROTEIN TARGET MIC 1024.0 ug.mL-1 10.1128/aac.00661-08
None No relevant target LogD 2.14 None 10.1021/jm0000564
None No relevant target LogD 2.499 None 10.1021/jm00135a006
None No relevant target LogD 2.62 None 10.1021/jm9910369
None No relevant target LogD 2.83 None 10.1021/jm00135a006
None No relevant target LogD 2.85 None 10.1016/j.ejmech.2021.113630
None No relevant target LogD 3.33 None 10.1016/j.ejmech.2008.11.009
None No relevant target LogD 9.4 None 10.1021/jm00135a006
None No relevant target Log Kmemb 1.5 None 10.1021/jm0309001
None No relevant target LogP 4.64 None 10.1021/jm9910369
None No relevant target LogP 5.04 None 10.1021/jm070524a
None No relevant target pKa 8.2 None 10.1007/s11095-013-1232-z
None No relevant target pKa 9.4 None 10.1007/s11095-013-1232-z
None No relevant target pKa 9.4 None 10.1016/j.ejmech.2009.06.004
None No relevant target pKa 9.4 None 10.1016/j.ejmech.2017.09.021
None No relevant target pKa 9.4 None 10.1021/jm0000564
None No relevant target pKa 9.4 None 10.1021/jm030408h
None No relevant target pKa 9.4 None 10.1021/jm070524a
None No relevant target pKa 9.49 None 10.1007/s11095-013-1232-z
None No relevant target pKa 9.5 None 10.1124/dmd.110.035998
None No relevant target Solubility 7.8 ug.mL-1 10.1016/j.bmc.2010.08.003
None Phospholipidosis Maximum test concentration that did not exhibit cytotoxicity 20.0 uM None
None Phospholipidosis Phospholipidosis nan None 10.1021/ci6004542
None Phospholipidosis Phospholipidosis nan None 10.1021/mp100103e
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Phospholipidosis Phospholipidosis as % of positive control 49.8 % None
None Unchecked ED50 4.5 mg.kg-1 10.1021/jm00186a018
None Unchecked Hepatotoxicity (acute) 18.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 12.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 9.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 6.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 41.0 nM 10.1021/jm9910369
None Unchecked IC50 840.0 nM None
None Unchecked IC50 1685.0 nM None
None Unchecked IC50 1992.0 nM None
None Unchecked IC50 2288.0 nM None
None Unchecked IC50 3000.0 nM 10.1021/jm00346a003
None Unchecked IC50 12000.0 nM 10.1021/jm300623u
None Unchecked IC50 nan None None
None Unchecked Ki 53.0 nM 10.1021/jm9910369
None Unchecked Ki 60.0 nM 10.1021/jm9910369
None Unchecked Ki 816.0 nM None
None Unchecked Ki 1123.0 nM None
None Unchecked Ki 1771.0 nM None
None Unchecked Ki 2088.0 nM None
None Unchecked Ki 80000.0 nM 10.1016/j.pharmthera.2004.10.013
None Unchecked Ki 130000.0 nM 10.1016/j.pharmthera.2004.10.013
None Unchecked Ki 160000.0 nM 10.1016/j.pharmthera.2004.10.013
None Unchecked Ki nan None None
None Unchecked Potency 1258.9 nM None
None Unchecked Potency 7943.3 nM None
None Unchecked Potency 11577.4 nM None
None Unchecked Potency 14125.4 nM None
None Unchecked Potency 16360.1 nM None
None Unchecked Ratio 0.19 None 10.1021/jm00400a005
None Unchecked Ratio 1.9 None 10.1021/jm00400a005
None Unchecked Ratio EC50 1.9 None 10.1128/aac.01777-09
None Unchecked Ratio IC50 2.0 None 10.1021/jm300623u
None Unchecked Ratio IC50 12.0 None 10.1021/jm300623u

Metabolism Information