Marinoquinoline J
AlkaPlorer ID: AK000805
Synonym: None
IUPAC Name: 5-methylpyrrolo[2,3-c]quinoline
Structure
SMILES: CN1C=C2C(=CC=N2)C3=CC=CC=C31
InChI: InChI=1S/C12H10N2/c1-14-8-11-9(6-7-13-11)10-4-2-3-5-12(10)14/h2-8H,1H3
InChIKey: QNMJVZJCKXNKJL-UHFFFAOYSA-N
Reference
Previously Uncultured Marine Bacteria Linked to Novel Alkaloid Production
PubChem CID: 46228107
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 182.226
TPSA？: 17.82
MolLogP？: 2.6781000000000015
Number of H-Donors: 0
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania donovani | Leishmania donovani | IC50 | 169100.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 3200.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Rattus norvegicus | L6 | IC50 | 159900.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 31500.0 | nM | 10.1016/j.bmc.2009.08.057 |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 76800.0 | nM | 10.1016/j.bmc.2009.08.057 |
| None | Unchecked | IC50 | 50000.0 | nM | 10.1016/j.bmc.2009.08.057 |