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D-pipecolic acid

AlkaPlorer ID: AK000832

Synonym: '(S)-piperidine-2-carboxylic acid', 'Pipecolic Acid', '', '(S)-(-)-pipecolic acid', 'D-pipecolate', '(R)-pipecolic acid', '(S)-pipecolic acid', '3105-95-1', 'L-pipecolic acid', 'pipecolate', 'Pipecolinic acid', '6-CARBOXYPIPERIDINE', 'L-Pipecolic acid', 'L-Pipecolate', 'Pipecolic acid', 'L-(-)-pipecolic acid', '535-75-1', '(R)-piperidine-2-carboxylic acid', 'L-pipecolate', '(S)-pipecolate', '2-Piperidinecarboxylic acid', '(R)-pipecolate'

IUPAC Name: (2S)-piperidine-2-carboxylic acid

Structure

SMILES: O=C(O)[C@@H]1CCCCN1

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InChI: InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1

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InChIKey: HXEACLLIILLPRG-YFKPBYRVSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Millettia erythrocalyx Millettia Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Prorocentrum micans Prorocentrum Prorocentraceae Prorocentrales Dinophyceae None None Eukaryota
Negombata magnifica Negombata Latrunculiidae Poecilosclerida Demospongiae Porifera Metazoa Eukaryota
Mycobacterium leprae Mycobacterium Mycobacteriaceae Mycobacteriales Actinomycetes Actinomycetota None Bacteria
Ononis vaginalis Ononis Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Alkanna cappadocica Alkanna Boraginaceae Boraginales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Homo sapiens Homo Hominidae Primates Mammalia Chordata Metazoa Eukaryota
Angelica gigas Angelica Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Angelica sinensis Angelica Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Buddleja cordata Buddleja Scrophulariaceae Lamiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Syncarpia hillii Syncarpia Myrtaceae Myrtales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Diospyros eriantha Diospyros Ebenaceae Ericales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Xenoacremonium recifei Xenoacremonium Nectriaceae Hypocreales Sordariomycetes Ascomycota Fungi Eukaryota
Crambe tatarica Crambe Brassicaceae Brassicales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Humulus lupulus Humulus Cannabaceae Rosales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Salvia hispanica Salvia Lamiaceae Lamiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pteris semipinnata Pteris Pteridaceae Polypodiales Polypodiopsida Streptophyta Viridiplantae Eukaryota
Juniperus rigida Juniperus Cupressaceae Cupressales Pinopsida Streptophyta Viridiplantae Eukaryota
Atalantia racemosa Atalantia Rutaceae Sapindales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Angelica acutiloba Angelica Apiaceae Apiales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Pogostemon cablin Pogostemon Lamiaceae Lamiales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 129.15900000000002

TPSA？: 49.33

MolLogP？: 0.2131000000000001

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Peroxisomal sarcosine oxidase Ki 130000.0 nM 10.1021/jm960331f
Homo sapiens Peroxisomal sarcosine oxidase Kiact 2.0 min-1 10.1021/jm960331f
Homo sapiens Proton-coupled amino acid transporter 1 Ki 11000000.0 nM 10.1016/j.bmc.2011.08.058
Homo sapiens Proton-coupled amino acid transporter 1 pKi -1.04 mM 10.1016/j.bmc.2011.08.058

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT002296 CC(=O)N1CCCCC1C(=O)O>>O=C(O)[C@@H]1CCCCN1 enzymemap_76457
AKRT012928 C[C@@H](O)[C@H](N)C(=O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O.O=C(O)[C@@H]1CCCCN1>>C[C@@H](O)[C@H](NC(=O)[C@@H]1CCCCN1)C(=O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O None
AKRT012939 C[C@@H](O)[C@H](N)C(=O)O.O=C(O)[C@@H]1CCCCN1>>C[C@@H](O)[C@H](NC(=O)[C@@H]1CCCCN1)C(=O)O enzymemap_90815
AKRT017200 NC(=O)[C@@H]1CCCCN1>>O=C(O)[C@@H]1CCCCN1 RXN-10757
AKRT018141 NCCCC[C@H](N)C(=O)O>>O=C(O)[C@@H]1CCCCN1 RXN-13654
AKRT022654 O=C(O)C1=NCCCC1>>O=C(O)[C@@H]1CCCCN1 RXN-8166
AKRT022716 O=C(O)CC(=O)[CoA].O=C(O)[C@@H]1CCCCN1>>O=C1CCN2CCCC[C@@H]12 65392
AKRT022717 O=C(O)CC(=O)[CoA].O=C(O)[C@@H]1CCCCN1>>O[C@@H]1CCN2CCCC[C@@H]12 67128
AKRT022718 O=C(O)CC(=O)[CoA].O=C(O)[C@@H]1CCCCN1>>O[C@H]1CCN2CCCC[C@@H]12 67132
AKRT023009 O=C(O)[C@@H]1CCCC=N1>>O=C(O)[C@@H]1CCCCN1 RXN-16267
AKRT023010 O=C(O)[C@@H]1CCCCN1>>*C(=O)[C@H]1CCCCN1 RXN-16682
AKRT023011 O=C(O)[C@@H]1CCCCN1>>O=C(O)C1=NCCCC1 RXN-14210
AKRT023012 O=C(O)[C@@H]1CCCCN1>>O=C(O)C1CCCC=N1 enzymemap_23423
AKRT023013 O=C(O)[C@@H]1CCCCN1>>O=C(O)[C@@H]1CCCC=N1 L-PIPECOLATE-OXIDASE-RXN
AKRT023014 O=C(O)[C@@H]1CCCCN1>>O=C(O)[C@@H]1CCCCN1O RXN-21030
AKRT023015 O=C(O)[C@@H]1CCCCN1>>O=C(O)[C@H]1CCCCN1 enzymemap_87007
AKRT023016 O=C(O)[C@@H]1CCCCN1>>O=C(O)[C@H]1NCCC[C@H]1O enzymemap_10774
AKRT023017 O=C(O)[C@@H]1CCCCN1>>O=C=O 65392