Mycalamide A
AlkaPlorer ID: AK000877
Synonym: None
IUPAC Name: (2S)-N-[(4aS,6R,8S,8aR)-6-(2,3-dihydroxypropyl)-8-methoxy-7,7-dimethyl-4a,6,8,8a-tetrahydro-4H-pyrano[3,2-d][1,3]dioxin-4-yl]-2-hydroxy-2-[(2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamide
Structure
SMILES: C=C1C[C@](OC)([C@H](O)C(O)=NC2OCO[C@H]3[C@@H]2O[C@H](CC(O)CO)C(C)(C)[C@@H]3OC)O[C@H](C)[C@@H]1C
InChI: InChI=1S/C24H41NO10/c1-12-9-24(31-7,35-14(3)13(12)2)19(28)21(29)25-22-18-17(32-11-33-22)20(30-6)23(4,5)16(34-18)8-15(27)10-26/h13-20,22,26-28H,1,8-11H2,2-7H3,(H,25,29)/t13-,14-,15?,16-,17+,18+,19-,20-,22?,24-/m1/s1
InChIKey: IJASURGZDJYQGF-UBZSBTAVSA-N
Reference
Peloruside A enhances apoptosis in H-ras-transformed cells and is cytotoxic to proliferating T cells
PubChem CID: 122770
CAS: 115185-92-7
LOTUS: LTS0129379
{NPAtlas: NPA028635
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Mycale | Mycalidae | Poecilosclerida | Demospongiae | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 503.5890000000003
TPSA？: 148.66
MolLogP？: 0.8985000000000012
Number of H-Donors: 4
Number of H-Acceptors: 10
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|