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name Structure Reference Source Properties Activities Metabolism

noradrenaline

AlkaPlorer ID: AK001041

Synonym: '', '(R)-(-)-norepinephrine', 'norepinephrine', 'MLS000028379', 'L-NOREPINEPHRINE', '(-)-noradrenaline', '(+/-)-NOREPINEPHRINE HYDROCHLORIDE', '(-)-norepinephrine', '(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol', '(R)-norepinephrine', '(-)-Norepinephrine', '(R)-noradrenaline', 'MLSMR', 'Norepinephrine', '4-(1R)-2-Amino-1-hydroxyethyl-1,2-benzenediol', 'Noradrenaline', 'SMR000058383', 'L-Noradrenaline', 'Arterenol', 'noradrenalina', '(-)-arterenol'

IUPAC Name: 4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol

Structure

SMILES: NC[C@@H](O)C1=CC=C(O)C(O)=C1

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InChI: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1

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InChIKey: SFLSHLFXELFNJZ-MRVPVSSYSA-N

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Reference

PubChem CID: 5814

CAS: 51-41-2

SuperNatural Ⅲ: SN0344051-01

NPASS: NPC118522

Source

Species Genus Family Order Class Phylum Kingdom Domain
Portulaca oleracea Portulaca Portulacaceae Caryophyllales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 169.17999999999998

TPSA？: 86.71000000000001

MolLogP？: 0.0898999999999999

Number of H-Donors: 4

Number of H-Acceptors: 4

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Potency 7943.3 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 7062.7 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 19905.4 nM None
Homo sapiens 15-hydroxyprostaglandin dehydrogenase [NAD+] Potency 35481.3 nM None
Homo sapiens ATP-dependent DNA helicase Q1 Potency 14125.4 nM None
Homo sapiens Bloom syndrome protein Potency 12589.3 nM None
Homo sapiens Cytochrome P450 3A4 Potency 31622.8 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 446.7 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 1000.0 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 3981.1 nM None
Homo sapiens DNA polymerase kappa Potency 3162.3 nM None
Homo sapiens DNA polymerase kappa Potency 11917.3 nM None
Homo sapiens Lysine-specific demethylase 4A Potency 89125.1 nM None
Homo sapiens Lysine-specific demethylase 4D-like Potency 3548.1 nM None
Homo sapiens MAP kinase ERK2 Potency 39810.7 nM None
Homo sapiens Microtubule-associated protein tau Potency 22387.2 nM None
Homo sapiens Microtubule-associated protein tau Potency 35481.3 nM None
Homo sapiens Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Potency 79432.8 nM None
Homo sapiens Runt-related transcription factor 1/Core-binding factor subunit beta Potency 2818.4 nM None
Homo sapiens Runt-related transcription factor 1/Core-binding factor subunit beta Potency 14125.4 nM None
Homo sapiens Thyroid hormone receptor beta-1 Potency 50118.7 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 398.1 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 17782.8 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 44668.4 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 112201.8 nM None
Rattus norvegicus Rattus norvegicus Activity nan None 10.1021/jm00223a039
None Unchecked Activity nan None 10.1021/jm00223a039
None Unchecked Potency 14068.4 nM None
None Unchecked Potency 14125.4 nM None
None Unchecked Potency 22387.2 nM None
None Unchecked Potency 39810.7 nM None

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT014661 C[SAH].NC[C@@H](O)c1ccc(O)c(O)c1>>CNC[C@@H](O)c1ccc(O)c(O)c1 enzymemap_26829