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name Structure Reference Source Properties Activities Metabolism

Thymidine

AlkaPlorer ID: AK001124

Synonym: None

IUPAC Name: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Structure

SMILES: CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O

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InChI: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1

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InChIKey: IQFYYKKMVGJFEH-XLPZGREQSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Biemna ehrenbergi Biemna Biemnidae Biemnida Demospongiae Porifera Metazoa Eukaryota

Properties Information

Molecule Weight: 242.231

TPSA？: 104.54999999999998

MolLogP？: -1.5142799999999992

Number of H-Donors: 3

Number of H-Acceptors: 6

RingCount: 2

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Artemia Artemia LC50 1000.0 ppm 10.1021/np50122a023
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.bmc.2008.04.045
Chlorocebus sabaeus Vero IC50 0.3 nM 10.1021/jm981132u
Chlorocebus sabaeus Vero IC50 0.4 nM 10.1021/jm981132u
Drosophila melanogaster Deoxynucleoside kinase Activity 60000.0 microM/min/mg 10.1016/j.bmcl.2009.12.097
Enterococcus faecium Enterococcus faecium ED50 11.0 uM 10.1021/jm00209a010
Escherichia coli K-12 Thymidine phosphorylase Activity 0.0 % 10.1016/j.bmc.2008.01.038
Escherichia coli K-12 Thymidine phosphorylase Activity 82.0 % 10.1016/j.bmc.2008.01.038
Escherichia coli K-12 Thymidine phosphorylase Activity 86.0 % 10.1016/j.bmc.2008.01.038
Escherichia coli K-12 Thymidine phosphorylase k cat 1770.0 s-1 10.1021/jm049494r
Escherichia coli K-12 Thymidine phosphorylase Kcat 1770.0 /s 10.1016/j.ejmech.2007.07.015
Escherichia coli K-12 Thymidine phosphorylase Km 240000.0 nM 10.1016/j.ejmech.2007.07.015
Escherichia coli K-12 Thymidine phosphorylase Km 240000.0 nM 10.1021/jm049494r
Escherichia coli K-12 Thymidine phosphorylase Km 2500000.0 nM 10.1016/j.bmc.2008.01.038
Escherichia coli K-12 Thymidine phosphorylase Phosphorolysis 72.0 % 10.1021/jm00051a006
Escherichia coli K-12 Thymidine phosphorylase Ratio 7400000.0 1/Ms 10.1021/jm049494r
Escherichia coli K-12 Thymidine phosphorylase Vmax 1.15 mM/min 10.1021/jm049494r
Escherichia coli K-12 Thymidine phosphorylase Vmax 5.2 mM/min 10.1016/j.bmc.2008.01.038
Hepatitis B virus Hepatitis B virus EC50 300.0 nM 10.1128/aac.00001-07
Hepatitis B virus Hepatitis B virus Inhibition 0.0 % 10.1016/j.bmcl.2010.08.120
Hepatitis B virus Hepatitis B virus Inhibition nan % 10.1016/j.bmcl.2010.08.120
Homo sapiens 143B CC50 600000.0 nM 10.1021/jm030544m
Homo sapiens 143B CC50 700000.0 nM 10.1021/jm030544m
Homo sapiens ATH-8 cell line ED50 100.0 uM 10.1021/jm00391a003
Homo sapiens ATH-8 cell line ID50 100.0 uM 10.1021/jm00391a003
Homo sapiens ATPase family AAA domain-containing protein 2 Kd 10000000.0 nM 10.1039/C4MD00237G
Homo sapiens CCRF-CEM Activity 10.0 % 10.1021/jm040144e
Homo sapiens CCRF-CEM Activity 18.0 % 10.1021/jm058234m
Homo sapiens CCRF-CEM Activity 20.0 % 10.1021/jm058234m
Homo sapiens CCRF-CEM Activity 40.0 % 10.1021/jm040144e
Homo sapiens CCRF-CEM Activity 92.0 % 10.1021/jm040144e
Homo sapiens CCRF-CEM Activity 96.0 % 10.1021/jm040144e
Homo sapiens CCRF-CEM CC50 10600.0 nM 10.1021/acs.jmedchem.0c00358
Homo sapiens CFPAC-1 Activity 0.0 % 10.1021/jm8005965
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 8912.5 nM None
Homo sapiens DNA cross-link repair 1A protein IC50 nan None 10.1016/j.bmc.2021.116369
Homo sapiens DNA cross-link repair 1A protein Inhibition nan % 10.1016/j.bmc.2021.116369
Homo sapiens HEL MCC 250000.0 nM 10.1016/j.bmcl.2018.09.019
Homo sapiens HeLa IC50 4000000.0 nM 10.1016/j.bmcl.2004.10.039
Homo sapiens HepG2 CC50 2100000.0 nM 10.1128/aac.00001-07
Homo sapiens HL-60 CC50 1760000.0 nM 10.1128/aac.00001-07
Homo sapiens HL-60 ID50 0.61 uM 10.1021/jm00403a026
Homo sapiens HL-60 ID50 336.0 uM 10.1021/jm00403a026
Homo sapiens HL-60 ID50 461.0 uM 10.1021/jm00403a026
Homo sapiens HL-60 ID50 901.0 uM 10.1021/jm00403a026
Homo sapiens MT4 Protection 10.0 % 10.1021/jm00391a003
Homo sapiens MT4 Protection 40.0 % 10.1021/jm00391a003
Homo sapiens MT4 Toxicity 10.0 % 10.1021/jm00391a003
Homo sapiens Solute carrier family 22 member 1 Activity nan None 10.1124/mol.51.6.913
Homo sapiens Thymidine kinase, cytosolic Activity nan None 10.1021/jm00100a029
Homo sapiens Thymidine kinase, cytosolic IC50 16.0 nM 10.1021/jm011128+
Homo sapiens Thymidine kinase, cytosolic IC50 26.0 nM 10.1021/jm011128+
Homo sapiens Thymidine kinase, cytosolic IC50 1800.0 nM 10.1021/jm011128+
Homo sapiens Thymidine kinase, cytosolic IC50 500000.0 nM 10.1021/jm011128+
Homo sapiens Thymidine kinase, cytosolic ID50 2.0 uM 10.1021/jm00100a029
Homo sapiens Thymidine kinase, cytosolic Inhibition nan % 10.1021/jm021108n
Homo sapiens Thymidine kinase, cytosolic k cat 0.35 s-1 10.1021/jm030241s
Homo sapiens Thymidine kinase, cytosolic Ki 200.0 nM 10.1021/jm030241s
Homo sapiens Thymidine kinase, cytosolic Ki 2000.0 nM 10.1021/jm00100a029
Homo sapiens Thymidine kinase, cytosolic Kinase activity 174.0 pM min-1*ml-1 10.1021/jm00088a015
Homo sapiens Thymidine kinase, cytosolic Kinase activity 585.0 pM min-1*ml-1 10.1021/jm00088a015
Homo sapiens Thymidine kinase, cytosolic Km 290.0 nM 10.1021/jm00388a021
Homo sapiens Thymidine kinase, cytosolic Km 660.0 nM 10.1021/jm00388a021
Homo sapiens Thymidine kinase, cytosolic Km 1000.0 nM 10.1021/jm010216r
Homo sapiens Thymidine kinase, cytosolic Km 1800.0 nM 10.1016/j.bmc.2010.03.023
Homo sapiens Thymidine kinase, cytosolic Km 2800.0 nM 10.1021/jm00100a029
Homo sapiens Thymidine kinase, cytosolic Km 3000.0 nM 10.1021/jm00163a043
Homo sapiens Thymidine kinase, cytosolic Km 4000.0 nM 10.1021/jm00163a043
Homo sapiens Thymidine kinase, cytosolic Km 49000.0 nM 10.1021/jm060404n
Homo sapiens Thymidine kinase, cytosolic Rate of phosphorylation 1.0 None 10.1021/jm020047q
Homo sapiens Thymidine kinase, cytosolic Ratio 439.0 /min.mg 10.1016/j.bmc.2010.03.023
Homo sapiens Thymidine kinase, cytosolic Relative velocity 6.0 % 10.1021/jm00394a039
Homo sapiens Thymidine kinase, cytosolic Relative velocity 100.0 % 10.1021/jm00394a039
Homo sapiens Thymidine kinase, cytosolic Relative Vmax 1.0 None 10.1021/jm010216r
Homo sapiens Thymidine kinase, cytosolic Relative Vmax 100.0 None 10.1021/jm010216r
Homo sapiens Thymidine kinase, cytosolic Vmax 790.0 nmol/mg.min 10.1016/j.bmc.2010.03.023
Homo sapiens Thymidine phosphorylase Km 187000.0 nM 10.1021/jm00182a029
Homo sapiens Thymidylate kinase Ki 180000.0 nM 10.1016/j.bmc.2008.04.045
Homo sapiens Thymidylate kinase Ki 180000.0 nM 10.1021/jm040847w
Human adenovirus 2 Human adenovirus 2 EC50 22000.0 nM 10.1016/j.bmcl.2018.09.019
Human alphaherpesvirus 1 Human alphaherpesvirus 1 ED50 1000.0 uM 10.1021/jm00403a026
Human alphaherpesvirus 1 Human alphaherpesvirus 1 ID50 nan None 10.1021/jm00381a015
Human alphaherpesvirus 2 Human alphaherpesvirus 2 ED50 1000.0 uM 10.1021/jm00403a026
Human herpesvirus 1 Thymidine kinase Km 1000.0 nM 10.1128/aac.01284-06
Human herpesvirus 1 Thymidine kinase Relative velocity 100.0 % 10.1021/jm00394a039
Human herpesvirus 1 Thymidine kinase Vmax 17.0 nmol/hr/microg 10.1128/aac.01284-06
Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1) Thymidine kinase IC50 1000.0 nM 10.1021/jm960278v
Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1) Thymidine kinase Km 810.0 nM 10.1021/jm00388a021
Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1) Thymidine kinase Relative velocity 100.0 % 10.1021/jm00394a039
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 3470.0 nM 10.1021/acs.jmedchem.0c00358
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 4110.0 nM 10.1021/acs.jmedchem.0c00358
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 10000.0 nM 10.1021/acs.jmedchem.0c00358
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 40000.0 nM 10.1021/jm00010a008
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 40000.0 nM 10.1021/jm00010a008
Macacine herpesvirus 1 Thymidine kinase Activity 100.0 % 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Activity 130.0 % 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase IC50 4100.0 nM 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Km 650.0 nM 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Km 700.0 nM 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Ratio 0.23 None 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Ratio 0.28 None 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Vmax 0.15 nmol/hr/microg 10.1128/aac.01284-06
Macacine herpesvirus 1 Thymidine kinase Vmax 0.2 nmol/hr/microg 10.1128/aac.01284-06
Mus musculus KBALB cell line CC50 95000.0 nM 10.1021/jm020299r
Mus musculus KBALB cell line CC50 970000.0 nM 10.1021/jm030544m
Mus musculus L1210 Concentration 0.0001 M 10.1021/jm00382a006
Mus musculus L1210 Concentration 0.0002 M 10.1021/jm00382a006
Mus musculus L1210 ID50 6.3 ug ml-1 10.1021/jm00359a008
Mus musculus L929 Incorporation rate 465.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus L929 Incorporation rate 2937.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus L929 Incorporation rate 28200.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus L929 Phosphorylation rate 100.0 uM 10.1021/jm0491896
Mus musculus LM Activity 53.0 None 10.1021/jm00378a036
Mus musculus LM Activity 2276.0 None 10.1021/jm00378a036
Mus musculus LM Incorporation rate 185.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus LM Incorporation rate 204.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus LM Incorporation rate 213.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus LM Incorporation rate 228.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus LM Incorporation rate 251.0 c.p.m. hr-1 10.1021/jm00155a033
Mus musculus LM Inhibition 98.5 % 10.1021/jm00378a036
Mus musculus MC-38 Activity nan None 10.1021/np060462b
Mus musculus Mus musculus Activity 25.5 % 10.1021/np50122a023
Mus musculus Mus musculus Ki 0.09 None 10.1021/jm00387a015
Mus musculus Mus musculus Ki 80000.0 nM 10.1021/jm00126a024
Mus musculus Thymidine kinase, cytosolic Relative phosphorylation 1.0 None 10.1021/jm990125i
Mus musculus Thymidylate synthase ID50 75.0 uM 10.1021/jm00403a026
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1016/j.bmc.2008.04.045
Mycobacterium tuberculosis Thymidylate kinase Ki 27000.0 nM 10.1016/j.bmc.2008.04.045
Mycobacterium tuberculosis Thymidylate kinase Ki 27000.0 nM 10.1016/s0960-894x(03)00643-7
Mycobacterium tuberculosis Thymidylate kinase Ki 27000.0 nM 10.1021/jm021108n
Mycobacterium tuberculosis Thymidylate kinase Ki 27000.0 nM 10.1021/jm040847w
Mycobacterium tuberculosis Thymidylate kinase Ki 27000.0 nM 10.1021/jm0492296
Mycobacterium tuberculosis Thymidylate kinase Ki 27000.0 nM None
Mycobacterium tuberculosis Thymidylate kinase Ki 715000.0 nM 10.1016/s0960-894x(03)00643-7
Rattus norvegicus Peripheral myelin protein 22 Potency 18105.6 nM None
Rattus norvegicus Thymidine kinase Km 1600.0 nM 10.1021/jm00349a007
Rattus norvegicus Thymidine kinase Km 8000.0 nM 10.1021/jm00349a007
Rattus norvegicus Thymidine kinase Phosphorylation rate 100.0 uM 10.1021/jm0491896
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 4.84 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.09 % 10.6019/CHEMBL4495565
Staphylococcus aureus Thymidine kinase Kcat 0.44 /s 10.1128/aac.00081-07
Staphylococcus aureus Thymidine kinase Kcat/Km 1.6 10'5/M/s 10.1128/aac.00081-07
Staphylococcus aureus Thymidine kinase Ki 257000.0 nM 10.1128/aac.00081-07
Staphylococcus aureus Thymidine kinase Km 2800.0 nM 10.1128/aac.00081-07
Staphylococcus aureus Thymidine kinase Vmax 1.2 U/mg 10.1128/aac.00081-07
Ureaplasma parvum serovar 3 (strain ATCC 700970) Thymidine kinase Km 1900.0 nM 10.1016/j.bmc.2010.03.023
Ureaplasma parvum serovar 3 (strain ATCC 700970) Thymidine kinase Ratio 637.0 /min.mg 10.1016/j.bmc.2010.03.023
Ureaplasma parvum serovar 3 (strain ATCC 700970) Thymidine kinase Vmax 1210.0 nmol/mg.min 10.1016/j.bmc.2010.03.023
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) Thymidine kinase Km 21000.0 nM 10.1128/aac.01447-06
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) Thymidine kinase Ratio 15.0 None 10.1128/aac.01447-06
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) Thymidine kinase Vmax 302.0 microM/min/mg 10.1128/aac.01447-06
None ADMET Activity nan None 10.1021/np060462b
None ADMET CC50 200.0 ug.mL-1 10.1016/j.bmcl.2010.08.120
None ADMET IZ 0.0 mm 10.1021/np060462b
None ADMET k cat 0.35 s-1 10.1021/jm030241s
None ADMET Km 1000.0 nM 10.1021/jm990125i
None ADMET Retention time 8.72 min 10.1021/jm0491896
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None KBALB-STK CC50 100000.0 nM 10.1021/jm020299r
None KBALB-STK CC50 650000.0 nM 10.1021/jm030544m
None NON-PROTEIN TARGET CC50 130000.0 nM 10.1021/jm020299r
None No relevant target P 0.055 None 10.1021/jm00163a043
None No relevant target P 0.06 None 10.1021/jm00051a006
None No relevant target pKa 9.8 None 10.1021/jm00209a010
None PRK ID50 0.25 ug ml-1 10.1021/jm00359a008
None PRK ID50 0.3 ug ml-1 10.1021/jm00359a008
None PRK ID50 10.0 ug ml-1 10.1021/jm00359a008
None PRK ID50 200.0 ug ml-1 10.1021/jm00359a008
None PRK ID50 300.0 ug ml-1 10.1021/jm00359a008
None Unchecked Activity nan None 10.1021/acs.jnatprod.5b00987
None Unchecked Delta Tm 0.2 None 10.1016/0960-894X(95)00050-4
None Unchecked Delta Tm 0.25 None 10.1016/0960-894X(95)00050-4
None Unchecked Delta Tm 0.3 None 10.1016/0960-894X(95)00050-4
None Unchecked Delta Tm 0.4 None 10.1016/0960-894X(95)00050-4
None Unchecked Delta Tm 2.5 None 10.1016/0960-894X(95)00050-4
None Unchecked Ki 200.0 nM 10.1021/jm030241s
None Unchecked Ki 2800.0 nM 10.1021/jm00196a025
None Unchecked Km 23000.0 nM 10.1128/aac.01447-06
None Unchecked Ratio 14.5 None 10.1128/aac.01447-06
None Unchecked Ratio nan None 10.1021/jm021108n
None Unchecked Ratio Ki 6.6 None 10.1021/jm040847w
None Unchecked Ratio Ki 7.0 None 10.1016/j.bmc.2008.04.045
None Unchecked Vmax 1.0 uM min-1 10.1021/jm00182a029
None Unchecked Vmax 334.0 microM/min/mg 10.1128/aac.01447-06

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT001065 *[C@H]1C[C@H](O)[C@@H](CO)O1.Cc1c[nH]c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O MNXR182919
AKRT004333 CC(=O)O[C@H]1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1CO>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_53273
AKRT014848 Cc1c[nH]c(=O)[nH]c1=O.O=P(O)(O)OC1C[C@H](O)[C@@H](CO)O1>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_38803
AKRT014849 Cc1c[nH]c(=O)[nH]c1=O.O=P(O)(O)O[C@@H]1C[C@H](O)[C@@H](CO)O1>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O R01570
AKRT014850 Cc1c[nH]c(=O)[nH]c1=O.O=P(O)(O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O MNXR136579
AKRT014851 Cc1c[nH]c(=O)[nH]c1=O.O=c1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_38612
AKRT014852 Cc1c[nH]c(=O)[nH]c1=O.OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C[C@@H]1O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O RXN-22630
AKRT015100 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O None
AKRT015101 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O.O=P(O)(O)Oc1cccc2ccccc12>>Cc1cn([C@H]2C[C@H](Oc3cccc4ccccc34)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_80748
AKRT015102 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O.O=c1[nH]cnc2nc[nH]c12>>OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C[C@@H]1O RXN-22630
AKRT015103 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O.O=c1cc[nH]c(=O)[nH]1>>Cc1c[nH]c(=O)[nH]c1=O enzymemap_39129
AKRT015104 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1c[nH]c(=O)[nH]c1=O THYM-PHOSPH-RXN
AKRT015105 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1c[nH]c(=O)[nH]c1=O.O=P(O)(O)O[C@@H]1C[C@H](O)[C@@H](CO)O1 None
AKRT015106 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)[nH]c1=O enzymemap_10803
AKRT015107 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O enzymemap_10802
AKRT015108 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O THYKI-RXN
AKRT015109 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O enzymemap_44155
AKRT015110 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>O=P(O)(O)O[C@@H]1C[C@H](O)[C@@H](CO)O1 THYM-PHOSPH-RXN
AKRT015111 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1CO enzymemap_10803
AKRT015112 Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>O=c1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1 enzymemap_39129
AKRT015127 Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O R01569
AKRT015134 Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3O)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_57180
AKRT015234 Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)Oc3ccc([N+](=O)[O-])cc3)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_57321
AKRT015243 Cc1cn([C@H]2C[C@H](OP(=O)(O)O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O 37247
AKRT015247 Cc1cn([C@H]2C[C@H](OP(=O)(O)Oc3cccc4ccccc34)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O enzymemap_80748