Molecule

Epinephrine

AlkaPlorer ID: AK001160

Synonym: None

IUPAC Name: 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

Structure

SMILES: CNC[C@H](O)C1=CC=C(O)C(O)=C1

InChI: InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChIKey: UCTWMZQNUQWSLP-VIFPVBQESA-N

Reference

Pregnane glycosides from Hemidesmus indicus

PubChem CID: 139148732

LOTUS: LTS0235972

SuperNatural Ⅲ: SN0366977-02

NPASS: NPC236347

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Gavia immer	Gavia	Gaviidae	Gaviiformes	Aves	Chordata	Metazoa	Eukaryota
Halimeda macroloba	Halimeda	Halimedaceae	Bryopsidales	Ulvophyceae	Chlorophyta	Viridiplantae	Eukaryota
Aruncus dioicus	Aruncus	Rosaceae	Rosales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Lecanora conizaeoides	Lecanora	Lecanoraceae	Lecanorales	Lecanoromycetes	Ascomycota	Fungi	Eukaryota
Artemisia oranensis	Artemisia	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Vitex megapotamica	Vitex	Lamiaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Homo sapiens	Homo	Hominidae	Primates	Mammalia	Chordata	Metazoa	Eukaryota
Cortinarius rubellus	Cortinarius	Cortinariaceae	Agaricales	Agaricomycetes	Basidiomycota	Fungi	Eukaryota
Strychnos fendleri	Strychnos	Loganiaceae	Gentianales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Hesperocyparis macrocarpa	Hesperocyparis	Cupressaceae	Cupressales	Pinopsida	Streptophyta	Viridiplantae	Eukaryota
Pleurotus citrinopileatus	Pleurotus	Pleurotaceae	Agaricales	Agaricomycetes	Basidiomycota	Fungi	Eukaryota
Vicia villosa	Vicia	Fabaceae	Fabales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Mus musculus	Mus	Muridae	Rodentia	Mammalia	Chordata	Metazoa	Eukaryota
Buxus sempervirens	Buxus	Buxaceae	Buxales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Bufo bufo	Bufo	Bufonidae	Anura	Amphibia	Chordata	Metazoa	Eukaryota
Saururus cernuus	Saururus	Saururaceae	Piperales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Potentilla multifida	Potentilla	Rosaceae	Rosales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Streptomyces plumbeus	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Portulaca oleracea	Portulaca	Portulacaceae	Caryophyllales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 183.207

TPSA？: 72.72

MolLogP？: 0.3506000000000001

Number of H-Donors: 4

Number of H-Acceptors: 4

RingCount: 1

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Bacillus subtilis	4'-phosphopantetheinyl transferase ffp	Potency	7079.5	nM	None
Bacillus subtilis	4'-phosphopantetheinyl transferase ffp	Potency	50118.7	nM	None
Bos taurus	Beta-2 adrenergic receptor	-Delta G	nan	None	10.1021/jm00401a004
Bos taurus	Progesterone receptor	IC50	nan	None	None
Bos taurus	Progesterone receptor	Ki	nan	None	None
Canis lupus familiaris	Beta-2 adrenergic receptor	Ki	660.0	nM	10.1021/jm990599h
Canis lupus familiaris	Beta-2 adrenergic receptor	Ki	1100.0	nM	10.1021/jm990599h
Cavia porcellus	Beta-1 adrenergic receptor	EC50	15.0	nM	10.1021/jm00019a001
Cavia porcellus	Beta-1 adrenergic receptor	EC50	260.0	nM	10.1021/jm00118a019
Cavia porcellus	Beta-1 adrenergic receptor	EC50	436.0	nM	10.1021/jm00019a001
Cavia porcellus	Beta-1 adrenergic receptor	Ki	3000.0	nM	10.1021/jm00118a019
Cavia porcellus	Beta-2 adrenergic receptor	EC50	15.0	nM	10.1021/jm00019a001
Cavia porcellus	Beta-2 adrenergic receptor	EC50	436.0	nM	10.1021/jm00019a001
Cavia porcellus	Cavia porcellus	EC50	400.0	nM	10.1021/jm00076a024
Cavia porcellus	Leukotriene C4 synthase	IC50	nan	None	None
Cavia porcellus	Leukotriene C4 synthase	Ki	nan	None	None
Cavia porcellus	Serotonin 4 (5-HT4) receptor	IC50	nan	None	None
Cavia porcellus	Serotonin 4 (5-HT4) receptor	Ki	nan	None	None
Danio rerio	Danio rerio	Activity	nan	None	10.1038/nchembio.307
Felis catus	Felis catus	Arterial pressure	23.8	mmHg	10.1021/jm00368a014
Felis catus	Felis catus	Arterial pressure	50.4	mmHg	10.1021/jm00368a014
Felis catus	Felis catus	Heart rate	47.4	beats min-1	10.1021/jm00368a014
Felis catus	Felis catus	Heart rate	57.0	beats min-1	10.1021/jm00368a014
Giardia intestinalis	Putative fructose-1,6-bisphosphate aldolase	Potency	11193.6	nM	None
Homo sapiens	Acetylcholinesterase	IC50	nan	None	None
Homo sapiens	Acetylcholinesterase	Ki	nan	None	None
Homo sapiens	Adenosine A1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A1 receptor	IC50	nan	None	None
Homo sapiens	Adenosine A1 receptor	Ki	nan	None	None
Homo sapiens	Adenosine A2a receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A2a receptor	IC50	nan	None	None
Homo sapiens	Adenosine A2a receptor	Ki	nan	None	None
Homo sapiens	Adenosine A3 receptor	AC50	17999.9	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A3 receptor	IC50	nan	None	None
Homo sapiens	Adenosine A3 receptor	Ki	nan	None	None
Homo sapiens	Adhesion G-protein coupled receptor F1	%Inhib (Mean)	-37.43	%	10.6019/CHEMBL5209801
Homo sapiens	Adhesion G-protein coupled receptor F1	%Max (Mean)	36.67	%	10.6019/CHEMBL5209801
Homo sapiens	Adrenergic receptor alpha-2	EC50	300.0	nM	10.1021/jm00118a019
Homo sapiens	Adrenergic receptor alpha-2	IC50	8.0	nM	10.1021/jm00390a021
Homo sapiens	Adrenergic receptor alpha-2	Ki	5.0	nM	10.1021/jm00118a019
Homo sapiens	Aldehyde dehydrogenase 1A1	Potency	14125.4	nM	None
Homo sapiens	Alpha-1a adrenergic receptor	AC50	2.6	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-1a adrenergic receptor	AC50	6.5	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-1a adrenergic receptor	AC50	6.7	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-1a adrenergic receptor	EC50	400.0	nM	10.1021/jm00118a019
Homo sapiens	Alpha-1a adrenergic receptor	Ki	2000.0	nM	10.1021/jm00118a019
Homo sapiens	Alpha-1b adrenergic receptor	EC50	75.0	nM	10.1021/acs.jnatprod.9b00418
Homo sapiens	Alpha-1d adrenergic receptor	IC50	449.0	nM	None
Homo sapiens	Alpha-1d adrenergic receptor	Ki	221.0	nM	None
Homo sapiens	Alpha-2a adrenergic receptor	AC50	11.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2a adrenergic receptor	AC50	84.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2a adrenergic receptor	AC50	8500.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2a adrenergic receptor	EC50	30.2	nM	10.1016/j.bmc.2016.05.043
Homo sapiens	Alpha-2a adrenergic receptor	IC50	737.0	nM	None
Homo sapiens	Alpha-2a adrenergic receptor	%Inhib (Mean)	-72.66	%	10.6019/CHEMBL5209801
Homo sapiens	Alpha-2a adrenergic receptor	Ki	160.0	nM	10.1016/j.bmc.2016.05.043
Homo sapiens	Alpha-2a adrenergic receptor	Ki	276.0	nM	None
Homo sapiens	Alpha-2a adrenergic receptor	%Max (Mean)	133.26	%	10.6019/CHEMBL5209801
Homo sapiens	Alpha-2b adrenergic receptor	AC50	4000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2b adrenergic receptor	AC50	7799.9	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2b adrenergic receptor	IC50	869.0	nM	None
Homo sapiens	Alpha-2b adrenergic receptor	Ki	397.0	nM	None
Homo sapiens	Alpha-2c adrenergic receptor	AC50	2700.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2c adrenergic receptor	AC50	10999.9	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2c adrenergic receptor	IC50	2449.0	nM	None
Homo sapiens	Alpha-2c adrenergic receptor	Ki	356.0	nM	None
Homo sapiens	Angiotensin II type 2 (AT-2) receptor	IC50	nan	None	None
Homo sapiens	Angiotensin II type 2 (AT-2) receptor	Ki	nan	None	None
Homo sapiens	Apelin receptor	%Inhib (Mean)	-7.63	%	10.6019/CHEMBL5209801
Homo sapiens	Apelin receptor	%Max (Mean)	-2.294	%	10.6019/CHEMBL5209801
Homo sapiens	Arachidonate 12-lipoxygenase	Potency	28183.8	nM	None
Homo sapiens	ATP-dependent DNA helicase Q1	Potency	17782.8	nM	None
Homo sapiens	ATP-dependent DNA helicase Q1	Potency	112201.8	nM	None
Homo sapiens	Beta-1 adrenergic receptor	AC50	970.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Beta-1 adrenergic receptor	EC50	290.0	nM	10.1021/acs.jnatprod.9b00418
Homo sapiens	Beta-1 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-1 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Beta-2 adrenergic receptor	AC50	22.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Beta-2 adrenergic receptor	-Delta G	6.92	None	10.1021/jm00401a004
Homo sapiens	Beta-2 adrenergic receptor	-Delta G	10.11	None	10.1021/jm00401a004
Homo sapiens	Beta-2 adrenergic receptor	IC50	284.0	nM	None
Homo sapiens	Beta-2 adrenergic receptor	%Inhib (Mean)	-172.54	%	10.6019/CHEMBL5209801
Homo sapiens	Beta-2 adrenergic receptor	Kd	630.0	nM	10.1016/j.ejmech.2008.12.016
Homo sapiens	Beta-2 adrenergic receptor	Kd	630.96	nM	10.1016/j.bmcl.2013.07.052
Homo sapiens	Beta-2 adrenergic receptor	Ki	196.0	nM	None
Homo sapiens	Beta-2 adrenergic receptor	Ki	360.0	nM	10.1016/j.bmc.2016.04.028
Homo sapiens	Beta-2 adrenergic receptor	%Max (Mean)	142.84	%	10.6019/CHEMBL5209801
Homo sapiens	Beta-3 adrenergic receptor	EC50	31.0	nM	10.1016/j.bmc.2007.11.060
Homo sapiens	Beta-3 adrenergic receptor	EC50	49.0	nM	10.1016/j.bmc.2007.11.060
Homo sapiens	Beta-3 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-3 adrenergic receptor	Intrinsic activity	99.0	%	10.1016/j.bmc.2007.11.060
Homo sapiens	Beta-3 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Bile salt export pump	AC50	300000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Bradykinin B2 receptor	IC50	nan	None	None
Homo sapiens	Bradykinin B2 receptor	Ki	nan	None	None
Homo sapiens	Bromodomain-containing protein 4	Delta TM	-0.08	C	None
Homo sapiens	C5a anaphylatoxin chemotactic receptor	%Inhib (Mean)	-12.3	%	10.6019/CHEMBL5209801
Homo sapiens	C5a anaphylatoxin chemotactic receptor	%Max (Mean)	-2.56	%	10.6019/CHEMBL5209801
Homo sapiens	Caco-2	logPapp	-6.02	None	10.1016/j.bmc.2009.08.022
Homo sapiens	Caco-2	logPapp	-6.02	None	10.1016/j.bmc.2011.03.011
Homo sapiens	Calcitonin receptor	IC50	nan	None	None
Homo sapiens	Calcitonin receptor	Ki	nan	None	None
Homo sapiens	Cannabinoid CB1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cannabinoid CB1 receptor	IC50	nan	None	None
Homo sapiens	Cannabinoid CB1 receptor	Ki	nan	None	None
Homo sapiens	Carbonic anhydrase I	Ka	0.09	uM	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase I	KA	0.09	uM	10.1016/j.bmc.2018.07.011
Homo sapiens	Carbonic anhydrase I	KA	0.09	uM	10.1016/j.bmcl.2016.11.027
Homo sapiens	Carbonic anhydrase I	KA	0.09	uM	10.1016/j.ejmech.2021.113875
Homo sapiens	Carbonic anhydrase I	Kcat	10.4	10^5/s	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase II	IC50	nan	None	None
Homo sapiens	Carbonic anhydrase II	Ka	96.0	uM	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase II	KA	96.0	uM	10.1016/j.bmc.2018.07.011
Homo sapiens	Carbonic anhydrase II	KA	96.0	uM	10.1016/j.bmcl.2016.11.027
Homo sapiens	Carbonic anhydrase II	KA	96.0	uM	10.1016/j.ejmech.2021.113875
Homo sapiens	Carbonic anhydrase II	Kcat	1.7	10^6/s	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase II	Ki	nan	None	None
Homo sapiens	Carbonic anhydrase IV	Ka	45.0	uM	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase IV	KA	45.0	uM	10.1016/j.ejmech.2021.113875
Homo sapiens	Carbonic anhydrase IV	Kcat	2.9	10^6/s	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase VA	Ka	63.0	uM	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase VA	KA	63.0	uM	10.1016/j.ejmech.2021.113875
Homo sapiens	Carbonic anhydrase VA	Kcat	3.9	10^5/s	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase VII	Ka	60.0	uM	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase VII	KA	60.0	uM	10.1016/j.ejmech.2021.113875
Homo sapiens	Carbonic anhydrase VII	Kcat	10.4	10^5/s	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase XIV	Ka	36.0	uM	10.1016/j.bmcl.2006.11.027
Homo sapiens	Carbonic anhydrase XIV	KA	36.0	uM	10.1016/j.ejmech.2021.113875
Homo sapiens	Carbonic anhydrase XIV	Kcat	4.5	10^5/s	10.1016/j.bmcl.2006.11.027
Homo sapiens	Casein kinase I delta	Delta TM	0.02	C	None
Homo sapiens	Caspase-1	IC50	nan	None	None
Homo sapiens	Caspase-1	Ki	nan	None	None
Homo sapiens	Cathepsin G	IC50	nan	None	None
Homo sapiens	Cathepsin G	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 2	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 2	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 4	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 4	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 5	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 5	Ki	nan	None	None
Homo sapiens	Cerebroside-sulfatase	Potency	13.5	nM	None
Homo sapiens	Cholecystokinin A receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cholecystokinin A receptor	IC50	nan	None	None
Homo sapiens	Cholecystokinin A receptor	Ki	nan	None	None
Homo sapiens	C-X3-C chemokine receptor 1	%Inhib (Mean)	-12.12	%	10.6019/CHEMBL5209801
Homo sapiens	C-X3-C chemokine receptor 1	%Max (Mean)	-2.85	%	10.6019/CHEMBL5209801
Homo sapiens	Cyclin-dependent kinase 2	Delta TM	0.78	C	None
Homo sapiens	Cyclooxygenase-1	IC50	nan	None	None
Homo sapiens	Cyclooxygenase-1	Ki	nan	None	None
Homo sapiens	Cyclooxygenase-2	AC50	4700.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cyclooxygenase-2	IC50	nan	None	None
Homo sapiens	Cyclooxygenase-2	Ki	nan	None	None
Homo sapiens	Cysteinyl leukotriene receptor 1	IC50	nan	None	None
Homo sapiens	Cysteinyl leukotriene receptor 1	Ki	nan	None	None
Homo sapiens	Cytochrome P450 1A2	AC50	15848.93	nM	None
Homo sapiens	Cytochrome P450 1A2	IC50	nan	None	None
Homo sapiens	Cytochrome P450 1A2	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2A6	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2A6	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2C19	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2C9	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2D6	AC50	39810.72	nM	None
Homo sapiens	Cytochrome P450 2D6	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2D6	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2D6	Potency	39810.7	nM	None
Homo sapiens	Cytochrome P450 2E1	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2E1	Ki	nan	None	None
Homo sapiens	Cytochrome P450 3A4	AC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	IC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	Ki	nan	None	None
Homo sapiens	Cytochrome P450 3A4	Potency	31622.8	nM	None
Homo sapiens	Delta opioid receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Delta opioid receptor	IC50	nan	None	None
Homo sapiens	Delta opioid receptor	Ki	nan	None	None
Homo sapiens	DNA-(apurinic or apyrimidinic site) lyase	Potency	3548.1	nM	None
Homo sapiens	DNA-(apurinic or apyrimidinic site) lyase	Potency	7943.3	nM	None
Homo sapiens	DNA-(apurinic or apyrimidinic site) lyase	Potency	8912.5	nM	None
Homo sapiens	DNA-(apurinic or apyrimidinic site) lyase	Potency	35481.3	nM	None
Homo sapiens	DNA polymerase kappa	Potency	1995.3	nM	None
Homo sapiens	DNA polymerase kappa	Potency	2667.9	nM	None
Homo sapiens	DNA polymerase kappa	Potency	11220.2	nM	None
Homo sapiens	DNA polymerase kappa	Potency	26679.5	nM	None
Homo sapiens	Dopamine D1 receptor	AC50	32.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D1 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D1 receptor	Kd	55000.0	nM	10.1021/jm950447w
Homo sapiens	Dopamine D1 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D1 receptor	Log 1/Kd	-4.74	None	10.1021/jm950447w
Homo sapiens	Dopamine D1 receptor	Potency	163.6	nM	None
Homo sapiens	Dopamine D1 receptor	Potency	410.9	nM	None
Homo sapiens	Dopamine D1 receptor	Potency	2511.9	nM	None
Homo sapiens	Dopamine D1 receptor	Potency	3162.3	nM	None
Homo sapiens	Dopamine D2 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D2 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D2 receptor	Ki	910.0	nM	10.1016/j.bmc.2016.04.028
Homo sapiens	Dopamine D2 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D3 receptor	AC50	8400.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D3 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D3 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D4 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D4 receptor	Ki	nan	None	None
Homo sapiens	Dopamine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine transporter	IC50	nan	None	None
Homo sapiens	Dopamine transporter	Ki	nan	None	None
Homo sapiens	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Potency	794.3	nM	None
Homo sapiens	Endothelin receptor ET-A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Endothelin receptor ET-A	IC50	nan	None	None
Homo sapiens	Endothelin receptor ET-A	Ki	nan	None	None
Homo sapiens	Epidermal growth factor receptor erbB1	IC50	nan	None	None
Homo sapiens	Epidermal growth factor receptor erbB1	Ki	nan	None	None
Homo sapiens	Equilibrative nucleoside transporter 1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Estrogen receptor alpha	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Estrogen receptor alpha	IC50	nan	None	None
Homo sapiens	Estrogen receptor alpha	Ki	nan	None	None
Homo sapiens	Estrogen receptor beta	IC50	nan	None	None
Homo sapiens	Estrogen receptor beta	Ki	nan	None	None
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	53.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	54.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	69.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	42.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	46.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	47.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	14985.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	15057.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	15078.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	15171.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	16285.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	16485.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	16657.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Total Cells	17835.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Growth Rate	-0.14	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.11	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Population Apoptotic (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	37.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	54.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Apoptotic (%)	77.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	39.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	37.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	42.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	44.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	47.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	48.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	70.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	67.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	76.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	88.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	92.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	94.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	96.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	97.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	98.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Normal (%)	99.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	31.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	42.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	46.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	119.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	123.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	126.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	132.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	135.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	142.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	143.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	146.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	150.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	153.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	165.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	168.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	169.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast	Total Cell Count	179.0	None	10.6019/CHEMBL5058577
Homo sapiens	Fibroblast growth factor receptor 3	Delta TM	0.34	C	None
Homo sapiens	Flap endonuclease 1	Potency	10621.3	nM	None
Homo sapiens	Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Ghrelin receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Glucagon-like peptide 1 receptor	%Inhib (Mean)	-27.31	%	10.6019/CHEMBL5209801
Homo sapiens	Glucagon-like peptide 1 receptor	%Max (Mean)	-2.632	%	10.6019/CHEMBL5209801
Homo sapiens	Glucagon-like peptide 1 receptor	Potency	25.1	nM	None
Homo sapiens	Glucocorticoid receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Glucocorticoid receptor	IC50	nan	None	None
Homo sapiens	Glucocorticoid receptor	Ki	nan	None	None
Homo sapiens	Glucocorticoid receptor	Potency	28183.8	nM	None
Homo sapiens	Glucose-dependent insulinotropic receptor	%Inhib (Mean)	-6.15	%	10.6019/CHEMBL5209801
Homo sapiens	Glucose-dependent insulinotropic receptor	%Max (Mean)	-3.055	%	10.6019/CHEMBL5209801
Homo sapiens	Glycogen synthase kinase-3 beta	Delta TM	-0.28	C	None
Homo sapiens	G-protein coupled receptor 120	%Inhib (Mean)	2.695	%	10.6019/CHEMBL5209801
Homo sapiens	G-protein coupled receptor 120	%Max (Mean)	-3.979	%	10.6019/CHEMBL5209801
Homo sapiens	G-protein coupled receptor 35	%Inhib (Mean)	-9.77	%	10.6019/CHEMBL5209801
Homo sapiens	G-protein coupled receptor 35	%Max (Mean)	8.258	%	10.6019/CHEMBL5209801
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	46.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	81.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	82.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	59.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	83.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	75.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	77.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	32.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	22878.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	29842.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	35035.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	45150.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	45535.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	60692.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	68271.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Total Cells	101135.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Growth Rate	0.03	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.73	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.83	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.84	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Population Apoptotic (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	33.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	44.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	58.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	69.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Apoptotic (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	51.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	71.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	75.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	78.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	81.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	39.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	31.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	43.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	57.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	62.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	85.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	88.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	34.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	43.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	44.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	48.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	55.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	63.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	64.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	83.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	59.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	60.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	78.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	79.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	81.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	90.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	91.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	92.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	93.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	94.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Normal (%)	96.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	30.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	31.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	43.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	21.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	27.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	29.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	39.0	%	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	218.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	228.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	244.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	249.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	272.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	293.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	312.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	314.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	315.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	371.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	475.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	482.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	486.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	648.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	678.0	None	10.6019/CHEMBL5058577
Homo sapiens	HEK-293T	Total Cell Count	1107.0	None	10.6019/CHEMBL5058577
Homo sapiens	HERG	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	HERG	IC50	nan	None	None
Homo sapiens	HERG	Ki	nan	None	None
Homo sapiens	Histamine H1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histamine H1 receptor	IC50	nan	None	None
Homo sapiens	Histamine H1 receptor	Ki	nan	None	None
Homo sapiens	Histamine H2 receptor	IC50	nan	None	None
Homo sapiens	Histamine H2 receptor	Ki	nan	None	None
Homo sapiens	Histamine H3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Potency	794.3	nM	None
Homo sapiens	HMG-CoA reductase	IC50	nan	None	None
Homo sapiens	HMG-CoA reductase	Ki	nan	None	None
Homo sapiens	Homo sapiens	DILI_Concern	nan	None	10.1016/j.drudis.2016.02.015
Homo sapiens	Homo sapiens	DILI_severity_class	0.0	None	10.1016/j.drudis.2016.02.015
Homo sapiens	Hypoxia-inducible factor 1 alpha	Potency	1584.9	nM	None
Homo sapiens	Interleukin-8 receptor A	IC50	nan	None	None
Homo sapiens	Interleukin-8 receptor A	Ki	nan	None	None
Homo sapiens	Interleukin-8 receptor B	IC50	nan	None	None
Homo sapiens	Interleukin-8 receptor B	Ki	nan	None	None
Homo sapiens	Kappa opioid receptor	IC50	nan	None	None
Homo sapiens	Kappa opioid receptor	Ki	nan	None	None
Homo sapiens	Leukocyte common antigen	IC50	nan	None	None
Homo sapiens	Leukocyte common antigen	Ki	nan	None	None
Homo sapiens	Leukocyte elastase	IC50	nan	None	None
Homo sapiens	Leukocyte elastase	Ki	nan	None	None
Homo sapiens	Lipoxin A4 receptor	%Inhib (Mean)	-10.32	%	10.6019/CHEMBL5209801
Homo sapiens	Lipoxin A4 receptor	%Max (Mean)	-2.884	%	10.6019/CHEMBL5209801
Homo sapiens	Lysine-specific demethylase 4D-like	Potency	7079.5	nM	None
Homo sapiens	MAP kinase ERK1	IC50	nan	None	None
Homo sapiens	MAP kinase ERK1	Ki	nan	None	None
Homo sapiens	MAP kinase ERK2	Delta TM	0.21	C	None
Homo sapiens	MAP kinase ERK2	IC50	nan	None	None
Homo sapiens	MAP kinase ERK2	Ki	nan	None	None
Homo sapiens	MAP kinase ERK2	Potency	3981.1	nM	None
Homo sapiens	MAP kinase p38 alpha	IC50	nan	None	None
Homo sapiens	MAP kinase p38 alpha	Ki	nan	None	None
Homo sapiens	Matrix metalloproteinase-1	IC50	nan	None	None
Homo sapiens	Matrix metalloproteinase-1	Ki	nan	None	None
Homo sapiens	Matrix metalloproteinase 9	IC50	nan	None	None
Homo sapiens	Matrix metalloproteinase 9	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 3	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Melanocortin receptor 3	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 3	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 4	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 4	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 5	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 5	Ki	nan	None	None
Homo sapiens	Menin/Histone-lysine N-methyltransferase MLL	Potency	39810.7	nM	None
Homo sapiens	Microtubule-associated protein tau	Potency	7943.3	nM	None
Homo sapiens	Microtubule-associated protein tau	Potency	11220.2	nM	None
Homo sapiens	Microtubule-associated protein tau	Potency	12589.3	nM	None
Homo sapiens	Microtubule-associated protein tau	Potency	14125.4	nM	None
Homo sapiens	Monoamine oxidase A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Monoamine oxidase A	IC50	nan	None	None
Homo sapiens	Monoamine oxidase A	Ki	nan	None	None
Homo sapiens	Motilin receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	M-phase phosphoprotein 8	Potency	37685.8	nM	None
Homo sapiens	Mu opioid receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Mu opioid receptor	IC50	nan	None	None
Homo sapiens	Mu opioid receptor	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M1	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M1	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M2	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M2	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M3	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M3	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M3	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M4	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M4	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M5	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M5	Ki	nan	None	None
Homo sapiens	Neurokinin 1 receptor	IC50	nan	None	None
Homo sapiens	Neurokinin 1 receptor	Ki	nan	None	None
Homo sapiens	Neurokinin 2 receptor	IC50	nan	None	None
Homo sapiens	Neurokinin 2 receptor	Ki	nan	None	None
Homo sapiens	Neuronal acetylcholine receptor protein alpha-4 subunit	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Neuropeptide Y receptor type 1	IC50	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 1	Ki	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 2	IC50	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 2	Ki	nan	None	None
Homo sapiens	Norepinephrine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Norepinephrine transporter	IC50	nan	None	None
Homo sapiens	Norepinephrine transporter	Ki	nan	None	None
Homo sapiens	Nuclear factor erythroid 2-related factor 2	Potency	48557.7	nM	None
Homo sapiens	Peregrin	Delta TM	-2.65	C	None
Homo sapiens	Peroxisome proliferator-activated receptor gamma	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 3A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 4D	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 5A	IC50	nan	None	None
Homo sapiens	Phosphodiesterase 5A	Ki	nan	None	None
Homo sapiens	Platelet activating factor receptor	IC50	nan	None	None
Homo sapiens	Platelet activating factor receptor	Ki	nan	None	None
Homo sapiens	Pregnane X receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Progesterone receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Protein kinase C alpha	IC50	nan	None	None
Homo sapiens	Protein kinase C alpha	Ki	nan	None	None
Homo sapiens	Receptor protein-tyrosine kinase erbB-2	IC50	nan	None	None
Homo sapiens	Receptor protein-tyrosine kinase erbB-2	Ki	nan	None	None
Homo sapiens	Runt-related transcription factor 1/Core-binding factor subunit beta	Potency	7943.3	nM	None
Homo sapiens	Runt-related transcription factor 1/Core-binding factor subunit beta	Potency	19952.6	nM	None
Homo sapiens	Serine/threonine-protein kinase Aurora-A	Delta TM	-0.18	C	None
Homo sapiens	Serine/threonine-protein kinase mTOR	Potency	23280.9	nM	None
Homo sapiens	Serine/threonine-protein kinase mTOR	Potency	26121.6	nM	None
Homo sapiens	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	IC50	nan	None	None
Homo sapiens	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	Ki	nan	None	None
Homo sapiens	Serotonin 1a (5-HT1a) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2a (5-HT2a) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2a (5-HT2a) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2a (5-HT2a) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 2b (5-HT2b) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2b (5-HT2b) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2b (5-HT2b) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 2c (5-HT2c) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2c (5-HT2c) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2c (5-HT2c) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 3a (5-HT3a) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 6 (5-HT6) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 6 (5-HT6) receptor	Ki	nan	None	None
Homo sapiens	Serotonin transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin transporter	IC50	nan	None	None
Homo sapiens	Serotonin transporter	Ki	nan	None	None
Homo sapiens	Sigma opioid receptor	IC50	nan	None	None
Homo sapiens	Sigma opioid receptor	Ki	nan	None	None
Homo sapiens	Solute carrier family 22 member 1	Inhibition	29.1	%	10.1021/jm8003152
Homo sapiens	Sphingosine 1-phosphate receptor Edg-1	%Inhib (Mean)	-20.01	%	10.6019/CHEMBL5209801
Homo sapiens	Sphingosine 1-phosphate receptor Edg-1	%Max (Mean)	-6.82	%	10.6019/CHEMBL5209801
Homo sapiens	Thromboxane-A synthase	IC50	nan	None	None
Homo sapiens	Thromboxane-A synthase	Ki	nan	None	None
Homo sapiens	Thyroid stimulating hormone receptor	Potency	31622.8	nM	None
Homo sapiens	Transcription intermediary factor 1-alpha	Delta TM	-0.05	C	None
Homo sapiens	Type-1 angiotensin II receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Type-1 angiotensin II receptor	%Inhib (Mean)	-19.48	%	10.6019/CHEMBL5209801
Homo sapiens	Type-1 angiotensin II receptor	%Max (Mean)	-6.4	%	10.6019/CHEMBL5209801
Homo sapiens	Tyrosine-protein kinase ABL	Delta TM	0.52	C	None
Homo sapiens	Tyrosine-protein kinase FYN	IC50	nan	None	None
Homo sapiens	Tyrosine-protein kinase FYN	Ki	nan	None	None
Homo sapiens	Tyrosine-protein kinase LCK	IC50	nan	None	None
Homo sapiens	Tyrosine-protein kinase LCK	Ki	nan	None	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	3162.3	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	3548.1	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	8414.4	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	11885.6	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	18356.4	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	23109.3	nM	None
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	33.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	71.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	74.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	76.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	16.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	8571.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	11828.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	14221.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	20657.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	20807.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	26450.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	31171.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Total Cells	44507.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Growth Rate	0.36	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.43	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.63	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.71	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.85	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.86	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.9	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.94	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.96	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	61.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	75.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	80.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	84.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	86.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	87.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	88.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	92.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	94.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Apoptotic (%)	100.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	19.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	26.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	28.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	31.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	33.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	35.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	36.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	39.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	41.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	48.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	40.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	44.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	45.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	49.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	54.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	56.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	64.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	65.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	66.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	72.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	74.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	17.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	24.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	3.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	8.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	12.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	20.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	25.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	38.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	82.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	88.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	89.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	90.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	93.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	96.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	97.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	98.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	99.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Normal (%)	100.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	22.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	23.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	0.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	1.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	2.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	4.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	6.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	9.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	10.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	13.0	%	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	65.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	84.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	87.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	92.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	96.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	105.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	150.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	175.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	195.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	199.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	209.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	215.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	229.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	278.0	None	10.6019/CHEMBL5058577
Homo sapiens	U2OS	Total Cell Count	333.0	None	10.6019/CHEMBL5058577
Homo sapiens	Ubiquitin carboxyl-terminal hydrolase 1	Potency	63095.7	nM	None
Homo sapiens	Vascular endothelial growth factor receptor 1	IC50	nan	None	None
Homo sapiens	Vascular endothelial growth factor receptor 1	Ki	nan	None	None
Homo sapiens	Vasoactive intestinal polypeptide receptor 1	IC50	nan	None	None
Homo sapiens	Vasoactive intestinal polypeptide receptor 1	Ki	nan	None	None
Homo sapiens	Vasopressin V1a receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Vasopressin V1a receptor	IC50	nan	None	None
Homo sapiens	Vasopressin V1a receptor	Ki	nan	None	None
Homo sapiens	Vitamin D receptor	Potency	31622.8	nM	None
Homo sapiens	Vitamin D receptor	Potency	50118.7	nM	None
Homo sapiens	Vitamin D receptor	Potency	79432.8	nM	None
Meleagris gallopavo	Erythrocyte beta receptor	Delta G	-7.86	None	10.1021/jm00152a017
Methanosarcina thermophila	Carbonic anhydrase	KA	39.0	uM	10.1016/j.bmcl.2016.11.027
Mus musculus	Mus musculus	Activity	0.13	uL/g/min	10.1073/pnas.0705611104
Mus musculus	Mus musculus	Activity	0.29	uL/g/min	10.1073/pnas.0705611104
Mus musculus	Mus musculus	Activity	0.47	uL/g/min	10.1073/pnas.0705611104
Mus musculus	Mus musculus	Activity	49.1	%	10.1073/pnas.0705611104
Mus musculus	Mus musculus	Activity	50.9	%	10.1073/pnas.0705611104
Mus musculus	Mus musculus	Activity	78.0	%	10.1073/pnas.0705611104
Mus musculus	Mus musculus	Activity	nan	None	10.1073/pnas.0705611104
Mus musculus	Nitric oxide synthase, inducible	IC50	nan	None	None
Mus musculus	Nitric oxide synthase, inducible	Ki	nan	None	None
Mus musculus	Solute carrier family 22 member 5	Activity	nan	None	10.1124/mol.59.2.358
Oryctolagus cuniculus	Angiotensin-converting enzyme	IC50	nan	None	None
Oryctolagus cuniculus	Angiotensin-converting enzyme	Ki	nan	None	None
Oryctolagus cuniculus	Arachidonate 15-lipoxygenase	IC50	3279.0	nM	None
Oryctolagus cuniculus	Arachidonate 15-lipoxygenase	Ki	nan	None	None
Rattus norvegicus	Adrenergic receptor alpha	IC50	17.0	nM	10.1021/jm00142a026
Rattus norvegicus	Adrenergic receptor alpha	Relative affinity	100.0	None	10.1021/jm00142a026
Rattus norvegicus	Adrenergic receptor alpha-1	EC50	4073.0	nM	10.1021/jm00019a001
Rattus norvegicus	Adrenergic receptor alpha-1	EC50	100000.0	nM	10.1021/jm00019a001
Rattus norvegicus	Adrenergic receptor alpha-1	Ki	200.0	nM	10.1021/jm00142a027
Rattus norvegicus	Adrenergic receptor alpha-1	Ki	1600.0	nM	10.1021/jm990599h
Rattus norvegicus	Adrenergic receptor alpha-1	Ki	2400.0	nM	10.1021/jm00076a024
Rattus norvegicus	Adrenergic receptor alpha-1	Ki	2800.0	nM	10.1021/jm990599h
Rattus norvegicus	Adrenergic receptor alpha-1	Ki	14000.0	nM	10.1021/jm00043a007
Rattus norvegicus	Adrenergic receptor alpha-2	Ki	13.0	nM	10.1021/jm990599h
Rattus norvegicus	Adrenergic receptor alpha-2	Ki	15.0	nM	10.1021/jm990599h
Rattus norvegicus	Adrenergic receptor alpha-2	Ki	38.0	nM	10.1021/jm00076a024
Rattus norvegicus	Adrenergic receptor alpha-2	Ki	160.0	nM	10.1021/np960482l
Rattus norvegicus	Adrenergic receptor beta	EC50	230.0	nM	10.1021/jm00076a024
Rattus norvegicus	Adrenergic receptor beta	EC50	230.0	nM	10.1021/jm00118a019
Rattus norvegicus	Adrenergic receptor beta	IC50	29000.0	nM	10.1021/jm00142a026
Rattus norvegicus	Adrenergic receptor beta	Relative affinity	100.0	None	10.1021/jm00142a026
Rattus norvegicus	Aldose reductase	IC50	nan	None	None
Rattus norvegicus	Aldose reductase	Ki	nan	None	None
Rattus norvegicus	Alpha-1a adrenergic receptor	IC50	628.0	nM	None
Rattus norvegicus	Alpha-1a adrenergic receptor	Ki	254.0	nM	None
Rattus norvegicus	Alpha-1b adrenergic receptor	IC50	1766.0	nM	None
Rattus norvegicus	Alpha-1b adrenergic receptor	Ki	977.0	nM	None
Rattus norvegicus	Androgen Receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Androgen Receptor	IC50	nan	None	None
Rattus norvegicus	Androgen Receptor	Ki	nan	None	None
Rattus norvegicus	Beta-1 adrenergic receptor	Ki	1100.0	nM	10.1021/jm990599h
Rattus norvegicus	Beta-1 adrenergic receptor	Ki	1200.0	nM	10.1021/jm00076a024
Rattus norvegicus	Beta-1 adrenergic receptor	Ki	2100.0	nM	10.1021/jm990599h
Rattus norvegicus	Beta-2 adrenergic receptor	Activity	nan	None	10.1016/j.bmc.2017.10.011
Rattus norvegicus	Beta-2 adrenergic receptor	Ki	720.0	nM	10.1021/jm00076a024
Rattus norvegicus	Catechol O-methyltransferase	Km	398000.0	nM	10.1021/jm00223a022
Rattus norvegicus	Catechol O-methyltransferase	Vmax	19.8	nmol/mg/min	10.1021/jm00223a022
Rattus norvegicus	Cyclooxygenase-1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Dopamine D1 receptor	KL	980.0	nM	10.1021/jm950447w
Rattus norvegicus	Dopamine D2 receptor	KL	128000.0	nM	10.1021/jm950447w
Rattus norvegicus	GABA receptor alpha-1 subunit	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Glycine receptor	IC50	nan	None	None
Rattus norvegicus	Glycine receptor	Ki	nan	None	None
Rattus norvegicus	Insulin receptor	IC50	nan	None	None
Rattus norvegicus	Insulin receptor	Ki	nan	None	None
Rattus norvegicus	Nitric-oxide synthase, brain	IC50	nan	None	None
Rattus norvegicus	Nitric-oxide synthase, brain	Ki	nan	None	None
Rattus norvegicus	Rattus norvegicus	Activity	0.12	10'-6mg/kg	10.1021/jm00204a009
Rattus norvegicus	Rattus norvegicus	ALB	37700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	38200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	38300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	39300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	42000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	43700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	43800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	44300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	44700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	260.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	282.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	291.17	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	319.83	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	367.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	368.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	383.4	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	404.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	425.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	42.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	47.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	48.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	48.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	49.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	51.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	53.2	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	53.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	57.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	70.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	74.5	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	75.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	76.17	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	79.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	82.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	84.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	86.83	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	89.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BASO	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BASOLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.4	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	2.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BP	16.0	mmHg	10.1021/jm991004l
Rattus norvegicus	Rattus norvegicus	BP	25.0	mmHg	10.1021/jm991004l
Rattus norvegicus	Rattus norvegicus	BUN	136.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	140.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	146.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	153.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	155.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	156.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	160.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	173.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	201.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	99.8	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	100.83	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	101.17	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	101.33	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	101.83	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	102.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	102.67	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	103.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	570.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	653.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	673.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	680.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	715.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	750.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	753.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	802.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	147.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	187.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	191.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	204.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	24000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	27000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	28000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	28330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	30000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	31330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	34000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	34200000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	34670000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	1.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	1.6	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	1.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	2.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	2.1	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	2.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	dP/dt	8416.0	mmHg s-1	10.1021/jm991004l
Rattus norvegicus	Rattus norvegicus	EOS	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	26.17	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	53.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	64.5	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	77.17	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	88.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	121.6	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	127.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	147.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.8	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	1.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1368.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1406.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1526.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1620.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1706.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1790.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1798.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1804.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1823.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	32.57	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	34.52	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	35.4	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	35.47	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	36.07	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	36.22	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	36.95	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	37.23	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	39.46	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	Heart rate	41.0	beats min-1	10.1021/jm991004l
Rattus norvegicus	Rattus norvegicus	HGB	124000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	126800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	128800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	131800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	132000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	134000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	136700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	140700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	143200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	75.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	94.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	102.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	104.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	111.2	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	118.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	147.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	159.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	162.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	8.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	8.5	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	8.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	9.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	9.17	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	9.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	7423.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	10984.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	10985.83	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	11755.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	12507.83	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	13213.6	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	13463.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	14257.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	14293.83	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	80.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	80.83	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	84.2	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	84.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	85.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	87.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	87.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	89.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	92.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	21.14	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	21.18	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	21.42	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	21.62	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	22.5	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	23.63	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	23.7	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	23.73	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.73	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	362700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	363000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	364200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	364300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	367800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	372300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	378000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	379000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	381000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	58.17	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	58.22	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	59.03	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	59.37	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	61.18	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	62.33	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	62.57	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	63.47	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	65.37	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	234.5	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	326.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	354.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	369.4	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	380.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	1.83	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	2.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	2.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	2.4	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	7.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	10.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	10.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	11.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	12.6	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	13.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	14.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	16.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	17.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	884.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	1222.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	1368.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	1616.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	1658.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	1753.5	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	2115.4	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	2414.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	3216.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	101.2	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	109.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	111.2	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	114.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	118.4	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	122.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	127.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	131.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	133.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	679170.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	904670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	976000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1016000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1271000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1309330.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1311000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1337000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1430670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.73	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.81	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.84	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.92	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.19	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.55	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.61	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.89	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	58300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	58700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	59200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60500.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	61000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	63000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	67000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	Ratio	2250.0	None	10.1021/jm00204a009
Rattus norvegicus	Rattus norvegicus	RBC	5230000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5590000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5640000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5710000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5770000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	6100000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	6110000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	6270000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	6780000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBCNUC	0.0	/100WBC	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBCNUC	0.17	/100WBC	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	144.7	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	144.85	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.07	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.52	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.67	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	147.16	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	147.57	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	147.8	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	150.1	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	TIME	0.003333	hr	10.1021/jm00204a009
Rattus norvegicus	Rattus norvegicus	Tissue Severity Score	nan	None	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	6.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	12.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	13.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	14.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	14.2	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	16.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	18.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	19.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	23.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	8730.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	12500.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	12770.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	13000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	15130.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	15370.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	15820.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	16380.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	17800.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Serotonin 1a (5-HT1a) receptor	IC50	nan	None	None
Rattus norvegicus	Serotonin 1a (5-HT1a) receptor	Ki	nan	None	None
Rattus norvegicus	Serotonin 1b (5-HT1b) receptor	IC50	nan	None	None
Rattus norvegicus	Serotonin 1b (5-HT1b) receptor	Ki	nan	None	None
Rattus norvegicus	Solute carrier family 22 member 1	Activity	nan	None	10.1038/sj.bjp.0702065
Rattus norvegicus	Solute carrier family 22 member 1	Ki	1600000.0	nM	10.1023/a:1013070128668
Rattus norvegicus	Solute carrier family 22 member 2	Ki	1191000.0	nM	10.1023/a:1013070128668
Rattus norvegicus	Solute carrier family 22 member 2	Km	1900000.0	nM	10.1074/jbc.273.47.30915
Rattus norvegicus	Thioredoxin reductase 1, cytoplasmic	Potency	21192.3	nM	None
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	-34.41	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	0.07	%	10.6019/CHEMBL4495565
Staphylococcus aureus	Staphylococcus aureus	Activity	77.0	%	10.1016/j.bmcl.2021.128259
Staphylococcus aureus	Staphylococcus aureus	Activity	79.0	%	10.1016/j.bmcl.2021.128259
Trypanosoma brucei	6-phospho-1-fructokinase	Potency	33807.8	nM	None
Trypanosoma brucei brucei	Phosphoglycerate kinase, glycosomal	Potency	37933.0	nM	None
Trypanosoma cruzi (strain CL Brener)	Carbonic anhydrase-like protein, putative	KA	100.0	uM	10.1016/j.bmc.2018.07.011
None	ADMET	delta logD	-0.9	None	10.1021/jm0000564
None	ADMET	F	20.0	%	10.1021/jm0000564
None	ADMET	Kpot A,B	0.01	None	10.1016/s0960-894x(99)00395-9
None	ADMET	Kpot A,B	0.089	None	10.1016/s0960-894x(99)00395-9
None	ADMET	Kpot A,B	0.09	None	10.1016/s0960-894x(99)00395-9
None	ADMET	Kpot A,B	0.65	None	10.1016/s0960-894x(99)00395-9
None	ADMET	logPapp	-6.02	None	10.1124/dmd.111.041665
None	Hepatotoxicity	Hepatotoxicity	nan	None	10.1021/tx900326k
None	Hepatotoxicity	HepSE_bilirubinemia	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_cholecystitis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_cholelithiasis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_cirrhosis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_Combined Scores	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_elevated liver function tests	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatic failure	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatic necrosis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatitis	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_hepatomegaly	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_jaundice	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_liver disease	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_liver fatty	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	HepSE_liver function tests abnormal	0.0	None	10.1371/journal.pcbi.1002310
None	Hepatotoxicity	LTKB_BD DILI severity score	nan	None	10.1016/j.drudis.2011.05.007
None	No relevant target	LogD	-3.49	None	10.1021/jm0000564
None	No relevant target	LogD	-2.59	None	10.1124/dmd.111.041665
None	No relevant target	LogP	0.59	None	10.1016/s0960-894x(99)00395-9
None	No relevant target	pKa	8.59	None	10.1016/j.bmc.2007.02.026
None	No relevant target	pKa	9.5	None	10.1021/jm00204a009
None	No relevant target	pKa	9.9	None	10.1021/jm0000564
None	Phospholipidosis	Phospholipidosis	nan	None	10.1080/15376510701857262
None	Unchecked	Ac50	17.78	uM	None
None	Unchecked	Ac50	22.39	uM	None
None	Unchecked	AC50	17782.8	nM	None
None	Unchecked	AC50	22387.2	nM	None
None	Unchecked	Activity	47.0	%	10.1038/nchembio801
None	Unchecked	Activity	84.0	%	10.1021/jm00196a008
None	Unchecked	Activity	nan	None	10.1038/nchembio801
None	Unchecked	[A]T,L	4.66	10'-8 /no of units.cm'3	10.1016/j.bmc.2008.12.063
None	Unchecked	[A]T,L	26926.0	/mol.dm'3	10.1016/j.bmc.2008.12.063
None	Unchecked	IC50	232.0	nM	None
None	Unchecked	IC50	nan	None	None
None	Unchecked	Intrinsic activity	0.75	None	10.1021/jm00207a015
None	Unchecked	KA	0.019	uM	10.1016/j.bmcl.2016.11.027
None	Unchecked	KA	0.72	uM	10.1016/j.bmcl.2016.01.078
None	Unchecked	KA	4.89	uM	10.1016/j.bmc.2018.07.011
None	Unchecked	Kcat	2.92	10'6/s	10.1016/j.bmcl.2016.11.027
None	Unchecked	Ki	100.0	nM	10.1038/nchembio801
None	Unchecked	Ki	110.0	nM	10.1038/nchembio801
None	Unchecked	Ki	154.0	nM	None
None	Unchecked	Ki	nan	None	None
None	Unchecked	-Log KD	-0.46	None	10.1021/jm00354a004
None	Unchecked	pKb	5.07	None	10.1021/jm00207a015
None	Unchecked	Potency	2818.4	nM	None
None	Unchecked	Potency	7943.3	nM	None
None	Unchecked	Potency	12589.3	nM	None
None	Unchecked	Potency	14125.4	nM	None
None	Unchecked	Potency	19952.6	nM	None
None	Unchecked	Ratio	400.0	None	10.1021/jm00118a019
None	Unchecked	Ratio Ki	2.5	None	10.1016/j.bmc.2016.04.028

Metabolism Information

AKRT ID	Reaction	Reaction Link ID
AKRT010588	CN1Cc2cc(O)c(O)cc2C(O)C1>>CNC[C@H](O)c1ccc(O)c(O)c1	MNXR103618
AKRT010759	CNC[C@H](O)c1ccc(O)c(O)c1.C[SAH]>>CNC[C@H](O)c1ccc(O)c(OC)c1	RXN-10909
AKRT010760	CNC[C@H](O)c1ccc(O)c(O)c1>>CN	RXN-10908
AKRT010761	CNC[C@H](O)c1ccc(O)c(O)c1>>CN1CC(O)C2=CC(=O)C(=O)C=C21	MNXR104046
AKRT010762	CNC[C@H](O)c1ccc(O)c(O)c1>>CNC[C@H](O)c1ccc(OS(=O)(=O)O)c(O)c1	enzymemap_49930
AKRT010763	CNC[C@H](O)c1ccc(O)c(O)c1>>O=CC(O)c1ccc(O)c(O)c1	R02919
AKRT010764	CNC[C@H](O)c1ccc(O)c(O)c1>>O=C[C@H](O)c1ccc(O)c(O)c1	RXN-10908
AKRT010768	CNC[C@H](O)c1ccc(O)c(OS(=O)(=O)O)c1>>CNC[C@H](O)c1ccc(O)c(O)c1	enzymemap_57880
AKRT010773	CNC[C@H](O)c1ccc(OS(=O)(=O)O)c(O)c1>>CNC[C@H](O)c1ccc(O)c(O)c1	enzymemap_57881
AKRT014564	C[SAH].CNC[C@H](O)c1ccc(O)c(O)c1>>CNC[C@H](O)c1ccc(O)c(OC)c1	enzymemap_27535
AKRT014663	C[SAH].NC[C@H](O)c1ccc(O)c(O)c1>>CNC[C@H](O)c1ccc(O)c(O)c1	RXN66-241