Navigation

name Structure Reference Source Properties Activities Metabolism

Thiram

AlkaPlorer ID: AK001249

Synonym: None

IUPAC Name: dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate

Structure

SMILES: CN(C)C(=S)SSC(=S)N(C)C

copy

InChI: InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3

copy

InChIKey: KUAZQDVKQLNFPE-UHFFFAOYSA-N

copy

Reference

PubChem CID: 5455

CAS: 137-26-8

SuperNatural Ⅲ: SN0195391

NPASS: NPC309367

COCONUT: CNP0334297

Source

Species Genus Family Order Class Phylum Kingdom Domain
Juncus effusus Juncus Juncaceae Poales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 240.444

TPSA？: 6.48

MolLogP？: 2.0608

Number of H-Donors: 0

Number of H-Acceptors: 4

RingCount: 0

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus anthracis Anthrax lethal factor Potency 10000.0 nM None
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Potency 3548.1 nM None
Botrytis cinerea Botrytis cinerea EC50 nan None 10.1021/jf903665f
Candida albicans Candida albicans MIC 6500.0 nM 10.1016/j.ejmech.2016.03.012
Candida parapsilosis Candida parapsilosis MIC 51800.0 nM 10.1016/j.ejmech.2016.03.012
Cricetulus griseus CHO Potency 4466.8 nM None
Cryptococcus neoformans Cryptococcus neoformans MIC 3200.0 nM 10.1016/j.ejmech.2016.03.012
Escherichia coli K-12 Beta-lactamase AmpC Potency 79432.8 nM None
Fusarium verticillioides Fusarium verticillioides IC50 1700.0 nM 10.1021/acs.jnatprod.7b00066
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 1584.9 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 14125.4 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 35481.3 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 39810.7 nM None
Homo sapiens 15-hydroxyprostaglandin dehydrogenase [NAD+] Potency 707.9 nM None
Homo sapiens 15-hydroxyprostaglandin dehydrogenase [NAD+] Potency 1000.0 nM None
Homo sapiens 786-0 GI50 17298.16 nM None
Homo sapiens 786-0 GI50 35156.04 nM None
Homo sapiens A498 GI50 45814.19 nM None
Homo sapiens A498 GI50 59979.11 nM None
Homo sapiens A549 GI50 3515.6 nM None
Homo sapiens A549 GI50 19678.86 nM None
Homo sapiens A549 IC50 nan None 10.1021/acs.jnatprod.7b00066
Homo sapiens ACHN GI50 19724.23 nM None
Homo sapiens ACHN GI50 55590.43 nM None
Homo sapiens Aldehyde dehydrogenase IC50 320.0 nM 10.1016/j.bmcl.2021.127958
Homo sapiens Aldehyde dehydrogenase 1A1 IC50 20.0 nM 10.1016/j.bmcl.2021.127958
Homo sapiens Aldehyde dehydrogenase 1A1 Potency 79.4 nM None
Homo sapiens Aldehyde dehydrogenase 1A1 Potency 125.9 nM None
Homo sapiens Aldehyde dehydrogenase 1A1 Potency 501.2 nM None
Homo sapiens Alpha-synuclein Potency 5011.9 nM None
Homo sapiens Anandamide amidohydrolase IC50 44668.36 nM 10.1021/jm901323s
Homo sapiens Androgen Receptor Potency 891.3 nM None
Homo sapiens Androgen Receptor Potency 22387.2 nM None
Homo sapiens Arachidonate 12-lipoxygenase Potency 2511.9 nM None
Homo sapiens Arachidonate 15-lipoxygenase Potency 125.9 nM None
Homo sapiens Ataxin-2 Potency 2511.9 nM None
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 25918.5 nM None
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 29081.0 nM None
Homo sapiens Beta-2 adrenergic receptor Potency 631.0 nM None
Homo sapiens Bile acid receptor FXR Potency 44668.4 nM None
Homo sapiens BT-549 GI50 14223.29 nM None
Homo sapiens BT-549 GI50 17218.69 nM None
Homo sapiens CAKI-1 GI50 21134.89 nM None
Homo sapiens CAKI-1 GI50 61517.69 nM None
Homo sapiens CCRF-CEM GI50 30.97 nM None
Homo sapiens CCRF-CEM GI50 77.45 nM None
Homo sapiens Cellular tumor antigen p53 Potency 31622.8 nM None
Homo sapiens COLO 205 GI50 37.5 nM None
Homo sapiens COLO 205 GI50 14689.26 nM None
Homo sapiens Cytochrome P450 3A4 Potency 15848.9 nM None
Homo sapiens DLD-1 GI50 2588.21 nM None
Homo sapiens DMS-114 GI50 124.45 nM None
Homo sapiens DMS-273 GI50 285.1 nM None
Homo sapiens DNA dC->dU-editing enzyme APOBEC-3G Potency 1122.0 nM None
Homo sapiens DU-145 GI50 37670.38 nM None
Homo sapiens DU-145 GI50 47097.73 nM None
Homo sapiens EKVX GI50 18535.32 nM None
Homo sapiens EKVX GI50 73451.39 nM None
Homo sapiens Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Potency 50.1 nM None
Homo sapiens Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Potency 12589.3 nM None
Homo sapiens Fructose-1,6-bisphosphatase IC50 2290.0 nM 10.1016/j.ejmech.2020.112500
Homo sapiens Gamma-butyrobetaine dioxygenase Activity nan None 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase IC50 5800.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase IC50 7900.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase IC50 14000.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase IC50 34000.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase IC50 56000.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase Kd 35000.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Gamma-butyrobetaine dioxygenase Kd 59000.0 nM 10.1016/j.bmcl.2014.09.035
Homo sapiens Geminin Potency 398.1 nM None
Homo sapiens Geminin Potency 1333.6 nM None
Homo sapiens Geminin Potency 21136.0 nM None
Homo sapiens Glucagon-like peptide 1 receptor Potency 28183.8 nM None
Homo sapiens Glutaminase kidney isoform, mitochondrial Potency 19952.6 nM None
Homo sapiens Glutaminase kidney isoform, mitochondrial Potency 35481.3 nM None
Homo sapiens Glyceraldehyde-3-phosphate dehydrogenase liver Potency 39810.7 nM None
Homo sapiens HCC 2998 GI50 16749.43 nM None
Homo sapiens HCC 2998 GI50 29308.93 nM None
Homo sapiens HCT-116 GI50 59.7 nM None
Homo sapiens HCT-116 GI50 23067.47 nM None
Homo sapiens HCT-15 GI50 13458.6 nM None
Homo sapiens HCT-15 GI50 47973.34 nM None
Homo sapiens Heat shock protein HSP 90-alpha AC50 7741.0 nM None
Homo sapiens HeLa IC50 2429100.0 nM 10.1016/j.ejmech.2016.03.012
Homo sapiens HeLa IC50 nan None 10.1021/acs.jnatprod.7b00066
Homo sapiens HepG2 Potency 100.0 nM None
Homo sapiens HERG Potency 44668.4 nM None
Homo sapiens Histone acetyltransferase GCN5 Potency 14125.4 nM None
Homo sapiens Histone acetyltransferase GCN5 Potency 15848.9 nM None
Homo sapiens Histone acetyltransferase GCN5 Potency 31622.8 nM None
Homo sapiens Histone deacetylase 6 Inhibition 14.77 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition 35.57 % 10.6019/CHEMBL4808148
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 IC50 550.0 nM 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Inhibition 50.0 % 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Inhibition nan % 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 1122.0 nM None
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 1258.9 nM None
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 IC50 1100.0 nM 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 Inhibition 50.0 % 10.1016/j.bmcl.2018.02.043
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 Inhibition nan % 10.1016/j.bmcl.2018.02.043
Homo sapiens HL-60 GI50 15.21 nM None
Homo sapiens HL-60 GI50 50.0 nM None
Homo sapiens HOP-18 GI50 100000.0 nM None
Homo sapiens HOP-62 GI50 67920.36 nM None
Homo sapiens HOP-92 GI50 18450.15 nM None
Homo sapiens HOP-92 GI50 59429.22 nM None
Homo sapiens Hs-578T GI50 44977.99 nM None
Homo sapiens Hs-578T GI50 100000.0 nM None
Homo sapiens HT-29 GI50 112.2 nM None
Homo sapiens HT-29 GI50 289.73 nM None
Homo sapiens Huntingtin Potency 1000.0 nM None
Homo sapiens IGROV-1 GI50 354.81 nM None
Homo sapiens IGROV-1 GI50 89949.76 nM None
Homo sapiens Interleukin-8 Potency 74978.0 nM None
Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic Potency 5.8 nM None
Homo sapiens K562 GI50 75.68 nM None
Homo sapiens K562 GI50 1513.56 nM None
Homo sapiens KM12 GI50 1066.6 nM None
Homo sapiens KM12 GI50 19054.61 nM None
Homo sapiens KM-20L2 GI50 1640.59 nM None
Homo sapiens Lethal(3)malignant brain tumor-like protein 1 Potency 2818.4 nM None
Homo sapiens LOX IMVI GI50 5407.54 nM None
Homo sapiens LOX IMVI GI50 22698.65 nM None
Homo sapiens LXFL 529 GI50 1981.53 nM None
Homo sapiens Lymphoblastoid cell Potency 158.5 nM None
Homo sapiens Lymphoblastoid cell Potency 199.5 nM None
Homo sapiens Lymphoblastoid cell Potency 251.2 nM None
Homo sapiens Lymphoblastoid cell Potency 316.2 nM None
Homo sapiens Lymphoblastoid cell Potency 398.1 nM None
Homo sapiens Lymphoblastoid cell Potency 501.2 nM None
Homo sapiens Lymphoblastoid cell Potency 794.3 nM None
Homo sapiens Lymphoblastoid cell Potency 1000.0 nM None
Homo sapiens Lymphoblastoid cell Potency 3981.1 nM None
Homo sapiens Lymphoblastoid cell Potency 10000.0 nM None
Homo sapiens Lymphoblastoid cell Potency 15848.9 nM None
Homo sapiens Lymphoblastoid cell Potency 19952.6 nM None
Homo sapiens Lymphoblastoid cell Potency 39810.7 nM None
Homo sapiens Lymphoblastoid cell Potency 50118.7 nM None
Homo sapiens Lysine-specific demethylase 4D-like Potency 25118.9 nM None
Homo sapiens Lysine-specific demethylase 4D-like Potency 31622.8 nM None
Homo sapiens Lysyl oxidase IC50 1040.0 nM 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase Inhibition 40.0 % 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase homolog 2 IC50 170.0 nM 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase homolog 2 Inhibition 40.0 % 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase homolog 3 IC50 110.0 nM 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase homolog 3 Inhibition 40.0 % 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase homolog 4 IC50 180.0 nM 10.1016/j.bmcl.2018.07.001
Homo sapiens Lysyl oxidase homolog 4 Inhibition 40.0 % 10.1016/j.bmcl.2018.07.001
Homo sapiens M14 GI50 17258.38 nM None
Homo sapiens M14 GI50 20606.3 nM None
Homo sapiens M19-MEL GI50 580.76 nM None
Homo sapiens Malme-3M GI50 12416.52 nM None
Homo sapiens Malme-3M GI50 20230.19 nM None
Homo sapiens MAP kinase ERK2 Potency 25118.9 nM None
Homo sapiens MCF7 GI50 17741.89 nM None
Homo sapiens MCF7 GI50 20796.97 nM None
Homo sapiens MCF7 IC50 nan None 10.1021/acs.jnatprod.7b00066
Homo sapiens MDA-MB-231 GI50 16788.04 nM None
Homo sapiens MDA-MB-231 GI50 20183.66 nM None
Homo sapiens MDA-MB-435 GI50 8035.26 nM None
Homo sapiens MDA-MB-435 GI50 21086.28 nM None
Homo sapiens MDA-N GI50 14060.48 nM None
Homo sapiens MDA-N GI50 19054.61 nM None
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 22387.2 nM None
Homo sapiens microRNA 21 Potency 7362.1 nM None
Homo sapiens Microtubule-associated protein tau Potency 1000.0 nM None
Homo sapiens Microtubule-associated protein tau Potency 2511.9 nM None
Homo sapiens Microtubule-associated protein tau Potency 2818.4 nM None
Homo sapiens Microtubule-associated protein tau Potency 15848.9 nM None
Homo sapiens MOLT-4 GI50 109.65 nM None
Homo sapiens MOLT-4 GI50 5321.08 nM None
Homo sapiens Monoglyceride lipase IC50 977.24 nM 10.1021/jm901323s
Homo sapiens Monoglyceride lipase Inhibition 50.0 % 10.1021/jm901323s
Homo sapiens NCI/ADR-RES GI50 17179.08 nM None
Homo sapiens NCI-H226 GI50 38370.72 nM None
Homo sapiens NCI-H226 GI50 78342.96 nM None
Homo sapiens NCI-H23 GI50 4497.8 nM None
Homo sapiens NCI-H23 GI50 20989.4 nM None
Homo sapiens NCI-H322M GI50 28313.92 nM None
Homo sapiens NCI-H322M GI50 58479.01 nM None
Homo sapiens NCI-H460 GI50 324.34 nM None
Homo sapiens NCI-H460 GI50 1425.61 nM None
Homo sapiens NCI-H522 GI50 35.08 nM None
Homo sapiens NCI-H522 GI50 73.11 nM None
Homo sapiens Neuropeptide S receptor Potency 4.5 nM None
Homo sapiens Neuropeptide S receptor Potency 316.2 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 27306.0 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 42163.2 nM None
Homo sapiens Nuclear factor NF-kappa-B p105 subunit Potency 31622.8 nM None
Homo sapiens Nuclear receptor ROR-gamma Potency 5308.0 nM None
Homo sapiens OVCAR-3 GI50 95.94 nM None
Homo sapiens OVCAR-3 GI50 352.37 nM None
Homo sapiens OVCAR-4 GI50 155.96 nM None
Homo sapiens OVCAR-4 GI50 14223.29 nM None
Homo sapiens OVCAR-5 GI50 16595.87 nM None
Homo sapiens OVCAR-5 GI50 58344.51 nM None
Homo sapiens OVCAR-8 GI50 5610.48 nM None
Homo sapiens OVCAR-8 GI50 16405.9 nM None
Homo sapiens p53-binding protein Mdm-2 EC50 180.0 nM None
Homo sapiens PC-3 GI50 941.89 nM None
Homo sapiens PC-3 GI50 24378.11 nM None
Homo sapiens Peroxisome proliferator-activated receptor delta Potency 50118.7 nM None
Homo sapiens Peroxisome proliferator-activated receptor gamma Potency 31622.8 nM None
Homo sapiens Prelamin-A/C Potency 1000.0 nM None
Homo sapiens Pyruvate kinase isozymes M1/M2 Potency 14125.4 nM None
Homo sapiens Retinoid X receptor alpha Potency 22387.2 nM None
Homo sapiens Retinoid X receptor alpha Potency 28183.8 nM None
Homo sapiens Retinoid X receptor alpha Potency 44668.4 nM None
Homo sapiens Retinoid X receptor alpha Potency 50118.7 nM None
Homo sapiens RPMI-8226 GI50 244.34 nM None
Homo sapiens RPMI-8226 GI50 13899.53 nM None
Homo sapiens Runt-related transcription factor 1/Core-binding factor subunit beta Potency 12589.3 nM None
Homo sapiens RXF 393 GI50 16634.13 nM None
Homo sapiens RXF 393 GI50 38547.84 nM None
Homo sapiens RXF 631 GI50 42169.65 nM None
Homo sapiens Serine/threonine-protein kinase PLK1 Potency 335.9 nM None
Homo sapiens SF-268 GI50 16069.41 nM None
Homo sapiens SF-268 GI50 42657.95 nM None
Homo sapiens SF-295 GI50 20989.4 nM None
Homo sapiens SF-295 GI50 28641.78 nM None
Homo sapiens SF-539 GI50 10739.89 nM None
Homo sapiens SF-539 GI50 40831.94 nM None
Homo sapiens SK-MEL-2 GI50 17021.59 nM None
Homo sapiens SK-MEL-2 GI50 57016.43 nM None
Homo sapiens SK-MEL-28 GI50 12971.79 nM None
Homo sapiens SK-MEL-28 GI50 23823.19 nM None
Homo sapiens SK-MEL-5 GI50 331.89 nM None
Homo sapiens SK-MEL-5 GI50 1047.13 nM None
Homo sapiens SK-OV-3 GI50 31841.98 nM None
Homo sapiens SK-OV-3 GI50 100000.0 nM None
Homo sapiens SN12C GI50 24266.1 nM None
Homo sapiens SN12C GI50 36391.5 nM None
Homo sapiens SNB-19 GI50 54575.79 nM None
Homo sapiens SNB-19 GI50 57809.6 nM None
Homo sapiens SNB-75 GI50 28054.34 nM None
Homo sapiens SNB-75 GI50 35974.93 nM None
Homo sapiens SNB-78 GI50 75509.22 nM None
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 104.36 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 99.01 % 10.1124/mol.112.084152
Homo sapiens SR GI50 67.92 nM None
Homo sapiens SR GI50 11885.02 nM None
Homo sapiens Survival motor neuron protein Potency 35481.3 nM None
Homo sapiens SW-620 GI50 1196.74 nM None
Homo sapiens SW-620 GI50 21827.3 nM None
Homo sapiens T47D GI50 18281.0 nM None
Homo sapiens T47D GI50 26242.19 nM None
Homo sapiens TAR DNA-binding protein 43 Potency 3981.1 nM None
Homo sapiens Thyroid hormone receptor beta-1 Potency 39810.7 nM None
Homo sapiens Thyroid hormone receptor beta-1 Potency 50118.7 nM None
Homo sapiens TK-10 GI50 26424.09 nM None
Homo sapiens TK-10 GI50 100000.0 nM None
Homo sapiens Tyrosine-protein kinase JAK2 Activity 2.375 um None
Homo sapiens Tyrosine-protein kinase JAK2 Activity 13.47 um None
Homo sapiens Tyrosine-protein kinase JAK2 IC50 223.0 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 9.2 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 130.0 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 133.4 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 145.8 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 19952.6 nM None
Homo sapiens U-251 GI50 14288.94 nM None
Homo sapiens U-251 GI50 17906.06 nM None
Homo sapiens UACC-257 GI50 4064.43 nM None
Homo sapiens UACC-257 GI50 28444.61 nM None
Homo sapiens UACC-62 GI50 2301.44 nM None
Homo sapiens UACC-62 GI50 3523.71 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 44668.4 nM None
Homo sapiens UO-31 GI50 31915.38 nM None
Homo sapiens UO-31 GI50 46451.53 nM None
Homo sapiens Vitamin D receptor Potency 2511.9 nM None
Homo sapiens Vitamin D receptor Potency 11220.2 nM None
Homo sapiens Vitamin D receptor Potency 44668.4 nM None
Homo sapiens XF498 GI50 4477.13 nM None
Human immunodeficiency virus 1 Aberrant vpr protein Potency 3162.3 nM None
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1021/jm960375o
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 0.76 None 10.1021/jm960375o
Middle East respiratory syndrome-related coronavirus (isolate UnitedKingdom/H123990006/2012) (Betacoronavirus England 1) (Humancoronavirus EMC) Replicase polyprotein 1ab IC50 10000.0 nM 10.6019/CHEMBL4495564
Middle East respiratory syndrome-related coronavirus (isolate UnitedKingdom/H123990006/2012) (Betacoronavirus England 1) (Humancoronavirus EMC) Replicase polyprotein 1ab Inhibition 48.0 % 10.6019/CHEMBL4495564
Mus musculus Nuclear receptor ROR-gamma Potency 112.2 nM None
Mus musculus Nuclear receptor ROR-gamma Potency 354.8 nM None
Mus musculus Nuclear receptor ROR-gamma Potency 891.3 nM None
Mus musculus Nuclear receptor ROR-gamma Potency 1000.0 nM None
Mus musculus Nuclear receptor ROR-gamma Potency 1122.0 nM None
Mycobacterium tuberculosis Bifunctional protein glmU IC50 89320.0 nM None
Oryctolagus cuniculus Fructose-bisphosphate aldolase A Potency 63095.7 nM None
Phomopsis asparagi Phomopsis asparagi EC50 nan None 10.1021/jf903665f
Photinus pyralis Luciferin 4-monooxygenase Potency 4053.3 nM None
Photinus pyralis Luciferin 4-monooxygenase Potency 9528.3 nM None
Phytophthora litchii Phytophthora litchii IC50 4600.0 nM 10.1021/acs.jnatprod.7b00066
Plasmodium falciparum Plasmodium falciparum Potency 329.4 nM None
Plasmodium falciparum Plasmodium falciparum Potency 414.7 nM None
Plasmodium falciparum Plasmodium falciparum Potency 756.9 nM None
Plasmodium falciparum Plasmodium falciparum Potency 849.2 nM None
Plasmodium falciparum 3D7 HSP90 AC50 3957.0 nM None
Plurivorosphaerella nawae Plurivorosphaerella nawae EC50 13.8 ug.mL-1 10.1016/j.cropro.2011.05.017
Plurivorosphaerella nawae Plurivorosphaerella nawae EC50 26.8 ug.mL-1 10.1016/j.cropro.2011.05.017
Pyricularia oryzae Pyricularia oryzae EC50 nan None 10.1021/jf903665f
Rattus norvegicus Nuclear receptor subfamily 1 group I member 2 Potency 79432.8 nM None
Rattus norvegicus Peripheral myelin protein 22 Potency 1438.2 nM None
Rattus norvegicus Peripheral myelin protein 22 Potency 22370.3 nM None
Rhizoctonia solani Rhizoctonia solani Activity 42.14 % 10.1016/j.cropro.2009.07.017
Rhizoctonia solani Rhizoctonia solani EC50 0.9 ug.mL-1 10.1021/jf903665f
Sclerotinia sclerotiorum Sclerotinia sclerotiorum EC50 nan None 10.1021/jf903665f
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab IC50 50.0 nM 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 100.04 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.2497 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.71 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 22.44 % 10.21203/rs.3.rs-23951/v1
Sporothrix schenckii Sporothrix schenckii MIC 51800.0 nM 10.1016/j.ejmech.2016.03.012
Trichomonas vaginalis Trichomonas vaginalis Activity 0.3 g 10.1016/j.ejmech.2016.03.012
Trichomonas vaginalis Trichomonas vaginalis Activity 4.45 mm2 10.1016/j.ejmech.2016.03.012
Trichomonas vaginalis Trichomonas vaginalis Activity 15.0 mm2 10.1016/j.ejmech.2016.03.012
Trichomonas vaginalis Trichomonas vaginalis Activity nan None 10.1016/j.ejmech.2016.03.012
Trichomonas vaginalis Trichomonas vaginalis MIC 12900.0 nM 10.1016/j.ejmech.2016.03.012
Trichomonas vaginalis Trichomonas vaginalis Ratio 16.0 None 10.1016/j.ejmech.2016.03.012
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 6500.0 nM 10.1016/j.ejmech.2016.03.012
Trypanosoma brucei 6-phospho-1-fructokinase Potency 28183.8 nM None
Trypanosoma brucei 6-phospho-1-fructokinase Potency 30131.3 nM None
Trypanosoma brucei brucei (strain 927/4 GUTat10.1) Putative uncharacterized protein Potency 4466.8 nM None
Trypanosoma brucei brucei (strain 927/4 GUTat10.1) Putative uncharacterized protein Potency 35481.3 nM None
None ADMET IC50 8391600.0 nM 10.1016/j.ejmech.2016.03.012
None Molecular identity unknown Potency 31622.8 nM None
None Molecular identity unknown Potency 33491.5 nM None
None Molecular identity unknown Potency 70794.6 nM None
None Unchecked Ac50 1.259 uM None
None Unchecked Ac50 12.59 uM None
None Unchecked AC50 1258.9 nM None
None Unchecked AC50 3400.0 nM None
None Unchecked AC50 12589.3 nM None
None Unchecked EC50 106.0 nM None
None Unchecked IC50 223.0 nM None
None Unchecked IC50 10000.0 nM None
None Unchecked IC50 20000.0 nM None
None Unchecked IC50 33330.0 nM None
None Unchecked IC50 40000.0 nM None
None Unchecked MEC 0.01 % 10.1016/j.ejmech.2016.03.012
None Unchecked Potency 14.6 nM None
None Unchecked Potency 66.2 nM None
None Unchecked Potency 631.0 nM None
None Unchecked Potency 1122.0 nM None
None Unchecked Potency 2238.7 nM None
None Unchecked Potency 2557.5 nM None
None Unchecked Potency 3548.1 nM None
None Unchecked Potency 5011.9 nM None
None Unchecked Potency 12589.3 nM None
None Unchecked Potency 16360.1 nM None
None Unchecked Potency 19952.6 nM None
None Unchecked Potency 20596.2 nM None
None Unchecked Potency 22387.2 nM None
None Unchecked Potency 23710.1 nM None
None Unchecked Potency 25118.9 nM None
None Unchecked Potency 28183.8 nM None
None Unchecked Potency 33807.8 nM None
None Unchecked Potency 35481.3 nM None
None Unchecked Selectivity Index 188.0 None 10.1016/j.ejmech.2016.03.012
None Unchecked Selectivity ratio 45.0 None 10.1021/jm901323s

Metabolism Information