Hexadecanoic acid; Amide
AlkaPlorer ID: AK001281
Synonym: Hexadecanamide, Palmitamide
IUPAC Name: hexadecanamide
Structure
SMILES: CCCCCCCCCCCCCCCC(=N)O
InChI: InChI=1S/C16H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H2,17,18)
InChIKey: HSEMFIZWXHQJAE-UHFFFAOYSA-N
Reference
Fatty acid amides from freshwater green alga Rhizoclonium hieroglyphicum
PubChem CID: 69421
CAS: 629-54-9
LOTUS: LTS0021816
SuperNatural Ⅲ: SN0134001
NPASS: NPC31557
COCONUT: CNP0243925
Source
Properties Information
Molecule Weight: 255.446
TPSA？: 44.08
MolLogP？: 6.002970000000006
Number of H-Donors: 2
Number of H-Acceptors: 1
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Cannabinoid CB1 receptor | Inhibition | 11.7 | % | 10.1021/jm0209679 |
| Homo sapiens | Cannabinoid CB2 receptor | Inhibition | 12.9 | % | 10.1021/jm0209679 |
| Homo sapiens | DNA-(apurinic or apyrimidinic site) lyase | Potency | 7079.5 | nM | None |
| Mus musculus | RAW264.7 | Activity | 100.0 | % | 10.1016/j.bmc.2008.10.015 |
| Rattus norvegicus | Anandamide amidohydrolase | Relative rate of hydrolysis | 0.72 | None | 10.1016/s0960-894x(00)00528-x |
| Rattus norvegicus | Rattus norvegicus | IC50 | 9772.37 | nM | 10.1021/jm0209679 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | 51.0 | % | 10.1021/jm0209679 |
| Rattus norvegicus | Transient receptor potential cation channel subfamily V member 2 | IC50 | 10000.0 | nM | 10.1021/acs.jmedchem.8b00734 |
| None | ADMET | Activity | 118.0 | % | 10.1016/j.bmc.2008.10.015 |