1,2,6,7-Tetrahydroxydibenz[cd,f]indol-4(5H)-one; 1,6,7-Tri-Me ether
AlkaPlorer ID: AK001717
Synonym: Enterocarpam I
IUPAC Name: 14-hydroxy-6,8,15-trimethoxy-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),2(7),3,5,8,12,14-heptaen-11-one
Structure
SMILES: COC1=CC=CC2=C1C(OC)=C1N=C(O)C3=CC(O)=C(OC)C2=C31
InChI: InChI=1S/C18H15NO5/c1-22-11-6-4-5-8-12(11)17(24-3)15-13-9(18(21)19-15)7-10(20)16(23-2)14(8)13/h4-7,20H,1-3H3,(H,19,21)
InChIKey: ZVCOGBCCWNHWGZ-UHFFFAOYSA-N
Reference
Aristolactams of Orophea enterocarpa
PubChem CID: 10358940
CAS: 102719-94-8
LOTUS: LTS0066065
SuperNatural Ⅲ: SN0481073
NPASS: NPC294244
COCONUT: CNP0317016
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Fissistigma oldhamii | Fissistigma | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Orophea enterocarpa | Orophea | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 325.3200000000001
TPSA？: 80.51
MolLogP？: 3.674100000000002
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| None | Platelet | Inhibition | 2.2 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 13.5 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 25.8 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 43.0 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 46.4 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 70.8 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 72.9 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 83.5 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 83.7 | % | 10.1021/np000063v |
| None | Platelet | Inhibition | 86.5 | % | 10.1021/np000063v |