Diaporphasine D
AlkaPlorer ID: AK001748
Synonym: None
IUPAC Name: methyl 7-hydroxy-3-(hydroxymethyl)-10-oxochromeno[3,2-c]pyridine-9-carboxylate
Structure
SMILES: COC(=O)C1=C2C(=CC(=C1)O)OC3=C(C2=O)C=NC(=C3)CO
InChI: InChI=1S/C15H11NO6/c1-21-15(20)9-3-8(18)4-12-13(9)14(19)10-5-16-7(6-17)2-11(10)22-12/h2-5,17-18H,6H2,1H3
InChIKey: JDZGBVCERSGMDB-UHFFFAOYSA-N
Reference
Alkaloids from the mangrove endophytic fungus Diaporthe phaseolorum SKS019
PubChem CID: 137656176
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Diaporthe phaseolorum | Diaporthe | Diaporthaceae | Diaporthales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 301.2540000000001
TPSA？: 109.86000000000001
MolLogP？: 1.3256999999999997
Number of H-Donors: 2
Number of H-Acceptors: 7
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HCT-116 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | HCT-116 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | HepG2 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | HepG2 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MCF-10A | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MCF-10A | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MDA-MB-435 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | MDA-MB-435 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | NCI-H460 | GI | nan | None | 10.1016/j.bmcl.2017.01.029 |
| Homo sapiens | NCI-H460 | IC50 | 50000.0 | nM | 10.1016/j.bmcl.2017.01.029 |