cyclo(L-Pro-L-Val)
AlkaPlorer ID: AK001756
Synonym: '', 'cyclo-Val-Pro-diketopiperazine', '156617-55-9', 'cyclo-Pro- Val', '27483-18-7', 'cyclo(D)-Pro-(D)-Val', '2854-40-2', 'Cyclo(D)-Pro-(D)-Val', '(3S,8aS)-3-Isopropylhexahydropyrrolo1,2-apyrazine-1,4-dione', 'Cyclo(D-Pro-L-Val)', 'Cyclo-(L-Pro-L-Val)', 'cyclo-(l-val-l-pro)', 'cyclo (L)-Pro-(L)-Val', 'cyclo(L-Pro-L-Val)'
IUPAC Name: (3R,8aS)-3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Structure
SMILES: CC(C)[C@H]1NC(=O)[C@@H]2CCCN2C1=O
InChI: InChI=1S/C10H16N2O2/c1-6(2)8-10(14)12-5-3-4-7(12)9(13)11-8/h6-8H,3-5H2,1-2H3,(H,11,13)/t7-,8+/m0/s1
InChIKey: XLUAWXQORJEMBD-JGVFFNPUSA-N
Reference
Diketopiperazines produced by an Aspergillus fumigatus Brazilian strain
PubChem CID: 927560
CAS: 27483-18-7
LOTUS: LTS0078208
SuperNatural Ⅲ: SN0433713-02
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Aspergillus fumigatus | Aspergillus | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 196.25
TPSA？: 49.41
MolLogP？: 0.1317999999999997
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HUVEC | Activity | nan | None | 10.1016/j.bmcl.2016.03.030 |
| Homo sapiens | HUVEC | Inhibition | nan | % | 10.1016/j.bmcl.2016.03.030 |
| Mus musculus | Mus musculus | Activity | 40.0 | % | 10.1016/j.bmcl.2016.03.030 |
| Mus musculus | Mus musculus | Activity | nan | None | 10.1016/j.bmcl.2016.03.030 |
| Mus musculus | Mus musculus | Inhibition | nan | % | 10.1016/j.bmcl.2016.03.030 |
| Vibrio anguillarum | Vibrio anguillarum | MIC | 0.14 | ug.mL-1 | 10.1021/np030233e |