Trichophycin F
AlkaPlorer ID: AK001799
Synonym: None
IUPAC Name: N-[(E,4E,9S,11R)-4-(chloromethylidene)-11-[(2R)-4-methoxy-6-oxo-2,3-dihydropyran-2-yl]-7,9-dimethyldodec-6-enyl]-N-methylpropanamide
Structure
SMILES: CCC(=O)N(C)CCC/C(=C\Cl)C/C=C(\C)C[C@@H](C)C[C@@H](C)[C@H]1CC(OC)=CC(=O)O1
InChI: InChI=1S/C25H40ClNO4/c1-7-24(28)27(5)12-8-9-21(17-26)11-10-18(2)13-19(3)14-20(4)23-15-22(30-6)16-25(29)31-23/h10,16-17,19-20,23H,7-9,11-15H2,1-6H3/b18-10+,21-17+/t19-,20-,23-/m1/s1
InChIKey: WOUKSKQTNWKNDH-BAAHFYCFSA-N
Reference
Trichophycins B–F, Chlorovinylidene-Containing Polyketides Isolated from a Cyanobacterial Bloom
PubChem CID: 146683653
LOTUS: LTS0170761
NPASS: NPC486301
{NPAtlas: NPA027280
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Trichodesmium thiebautii | Trichodesmium | Microcoleaceae | Oscillatoriales | Cyanophyceae | Cyanobacteriota | None | Bacteria |
| Trichodesmium sp. | Trichodesmium | Microcoleaceae | Oscillatoriales | Cyanophyceae | Cyanobacteriota | None | Bacteria |
Properties Information
Molecule Weight: 454.0510000000003
TPSA？: 55.84
MolLogP？: 5.992300000000006
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | N2a | EC50 | 14000.0 | nM | 10.1021/acs.jnatprod.0c00550 |