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Eudistomin Y3

AlkaPlorer ID: AK002048

Synonym: None

IUPAC Name: (3-bromo-4-hydroxyphenyl)-(9H-pyrido[3,4-b]indol-1-yl)methanone

Structure

SMILES: C1=CC=C2C(=C1)C3=C(N2)C(=NC=C3)C(=O)C4=CC(=C(C=C4)O)Br

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InChI: InChI=1S/C18H11BrN2O2/c19-13-9-10(5-6-15(13)22)18(23)17-16-12(7-8-20-17)11-3-1-2-4-14(11)21-16/h1-9,21-22H

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InChIKey: RVFSIJWZHTVFJY-UHFFFAOYSA-N

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Properties Information

Molecule Weight: 367.20199999999994

TPSA？: 65.98

MolLogP？: 4.415200000000002

Number of H-Donors: 2

Number of H-Acceptors: 3

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Aspergillus fumigatus Aspergillus fumigatus MIC 100.0 ug.mL-1 10.1016/j.bmc.2012.05.002
Bacillus subtilis Bacillus subtilis MIC 12.5 ug.mL-1 10.1016/j.bmc.2012.05.002
Candida albicans Candida albicans MIC 100.0 ug.mL-1 10.1016/j.bmc.2012.05.002
Candida albicans Isocitrate lyase IC50 272300.0 nM 10.1016/j.bmc.2012.05.002
Escherichia coli Escherichia coli MIC 100.0 ug.mL-1 10.1016/j.bmc.2012.05.002
Homo sapiens A549 LC50 252700.0 nM 10.1016/j.bmc.2012.05.002
Micrococcus luteus Micrococcus luteus MIC 12.5 ug.mL-1 10.1016/j.bmc.2012.05.002
Proteus vulgaris Proteus vulgaris MIC 6.25 ug.mL-1 10.1016/j.bmc.2012.05.002
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 6.25 ug.mL-1 10.1016/j.bmc.2012.05.002
Staphylococcus aureus Sortase A IC50 272300.0 nM 10.1016/j.bmc.2012.05.002
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1016/j.bmc.2012.05.002
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 100.0 ug.mL-1 10.1016/j.bmc.2012.05.002
Trichophyton rubrum Trichophyton rubrum MIC 100.0 ug.mL-1 10.1016/j.bmc.2012.05.002
None Unchecked IC50 22500.0 nM 10.1016/j.bmc.2012.05.002

Metabolism Information