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Perlolyrin

AlkaPlorer ID: AK002612

Synonym: None

IUPAC Name: [5-(9H-pyrido[3,4-b]indol-1-yl)furan-2-yl]methanol

Structure

SMILES: OCC1=CC=C(C2=NC=CC3=C2NC2=CC=CC=C23)O1

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InChI: InChI=1S/C16H12N2O2/c19-9-10-5-6-14(20-10)16-15-12(7-8-17-16)11-3-1-2-4-13(11)18-15/h1-8,18-19H,9H2

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InChIKey: KFUCYPGCMLPUMT-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Crocus sativus Crocus Iridaceae Asparagales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 264.28400000000005

TPSA？: 62.05

MolLogP？: 3.468400000000001

Number of H-Donors: 2

Number of H-Acceptors: 3

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis Bacillus subtilis Activity nan None 10.1021/np800248s
Candida albicans Candida albicans Activity nan None 10.1021/np800248s
Chlorella sorokiniana Chlorella sorokiniana Activity nan None 10.1021/np800248s
Chlorella vulgaris Chlorella vulgaris Activity nan None 10.1021/np800248s
Desmodesmus subspicatus Desmodesmus subspicatus Activity nan None 10.1021/np800248s
Escherichia coli Escherichia coli Activity nan None 10.1021/np800248s
Homo sapiens Phosphodiesterase 5A IC50 9300.0 nM 10.1016/j.ejmech.2018.02.039
Homo sapiens Phosphodiesterase 5A IC50 9300.0 nM 10.1016/j.ejmech.2018.09.028
Mus musculus RAW264.7 IC50 8700.0 nM 10.1016/j.bmcl.2017.04.072
Rhizomucor miehei Rhizomucor miehei Activity nan None 10.1021/np800248s
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/np800248s
Streptomyces viridochromogenes Streptomyces viridochromogenes Activity nan None 10.1021/np800248s
None NON-PROTEIN TARGET IC50 0.45 ug.mL-1 10.1021/np100902f
None NON-PROTEIN TARGET IC50 1.68 ug.mL-1 10.1021/np100902f
None NON-PROTEIN TARGET Inhibition nan % 10.1021/np100902f

Metabolism Information