6-Hydroxy-3-pyridinecarboxylic acid; NH-form, N-Me, amide
AlkaPlorer ID: AK002631
Synonym: N-Methyl-2-pyridone-5-carboxamide
IUPAC Name: 1-methyl-6-oxopyridine-3-carboxamide
Structure
SMILES: CN1C=C(C(=N)O)C=CC1=O
InChI: InChI=1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)
InChIKey: JLQSXXWTCJPCBC-UHFFFAOYSA-N
Reference
Biosynthesis of N-methyl-5-carboxamide-2-pyridone from Trewia nudiflora
PubChem CID: 69698
CAS: 701-44-0
LOTUS: LTS0173819
NPASS: NPC281587
COCONUT: CNP0249493
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Mallotus barbatus | Mallotus | Euphorbiaceae | Malpighiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Homo sapiens | Homo | Hominidae | Primates | Mammalia | Chordata | Metazoa | Eukaryota |
| Mus musculus | Mus | Muridae | Rodentia | Mammalia | Chordata | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 152.15299999999996
TPSA？: 66.08000000000001
MolLogP？: 0.2686699999999998
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Nicotinamide N-methyltransferase | IC50 | 30000.0 | nM | 10.1016/j.bmcl.2018.01.058 |