10-Epi-tazopsine
AlkaPlorer ID: AK002800
Synonym: None
IUPAC Name: (1S,8S,9R,12S,13S)-4,11-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10-tetraene-3,8,12,13-tetrol
Structure
SMILES: COC1=C(C2=C(C=C1)[C@@H]([C@H]3C4=C([C@H]([C@H](C[C@]42CCN3)O)O)OC)O)O
InChI: InChI=1S/C18H23NO6/c1-24-10-4-3-8-11(16(10)23)18-5-6-19-13(14(8)21)12(18)17(25-2)15(22)9(20)7-18/h3-4,9,13-15,19-23H,5-7H2,1-2H3/t9-,13+,14-,15-,18-/m0/s1
InChIKey: CQFMGBHPLGTYRE-ANUCULNSSA-N
Reference
Isolation and antimalarial activity of new morphinan alkaloids on Plasmodium yoelii liver stage
PubChem CID: 25022686
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Strychnopsis thouarsii | Strychnopsis | Menispermaceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 349.383
TPSA？: 111.41000000000001
MolLogP？: 0.07349999999999979
Number of H-Donors: 5
Number of H-Acceptors: 7
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium yoelii yoelii | Plasmodium yoelii yoelii | IC50 | 16100.0 | nM | 10.1016/j.bmc.2008.04.033 |
| None | ADMET | TC50 | 388.3 | uM | 10.1016/j.bmc.2008.04.033 |
| None | Unchecked | Ratio | 24.1 | None | 10.1016/j.bmc.2008.04.033 |