Cyclamic Acid
AlkaPlorer ID: AK002897
Synonym: None
IUPAC Name: cyclohexylsulfamic acid
Structure
SMILES: O=S(=O)(O)NC1CCCCC1
InChI: InChI=1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
InChIKey: HCAJEUSONLESMK-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 179.24099999999993
TPSA？: 66.4
MolLogP？: 0.7114999999999998
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Histone deacetylase 6 | Inhibition | -50.45 | % | 10.6019/CHEMBL4808148 |
| Homo sapiens | Histone deacetylase 6 | Inhibition | -0.33 | % | 10.6019/CHEMBL4808148 |
| Homo sapiens | Muscarinic acetylcholine receptor | Activity | nan | None | None |
| Homo sapiens | T1R1/T1R3 | Activity | nan | None | None |
| Homo sapiens | T1R1/T1R3 | FC | 2.0 | None | None |
| Homo sapiens | Taste receptor type 1 member 2 | Activity | nan | None | None |
| Homo sapiens | Taste receptor type 1 member 3 | Activity | nan | None | None |
| Homo sapiens | Taste receptor type 2 member 31 | EC50 | nan | None | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 6745.6 | nM | None |
| Severe acute respiratory syndrome coronavirus 2 | Replicase polyprotein 1ab | Inhibition | 11.28 | % | 10.6019/CHEMBL4495564 |
| Severe acute respiratory syndrome coronavirus 2 | Replicase polyprotein 1ab | Inhibition | 16.32 | % | 10.6019/CHEMBL4495564 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | IC50 | 19952.62 | nM | 10.6019/CHEMBL4651402 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | IC50 | 20000.0 | nM | 10.6019/CHEMBL4651402 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | -0.13 | % | 10.6019/CHEMBL4495565 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | 0.11 | % | 10.6019/CHEMBL4495565 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | 2.77 | % | 10.21203/rs.3.rs-23951/v1 |
| None | Unchecked | Ac50 | 1.778 | uM | None |
| None | Unchecked | Ac50 | 3.162 | uM | None |
| None | Unchecked | Ac50 | 39.81 | uM | None |
| None | Unchecked | AC50 | 1778.3 | nM | None |
| None | Unchecked | AC50 | 3162.3 | nM | None |
| None | Unchecked | AC50 | 39810.7 | nM | None |