AXM
AlkaPlorer ID: AK002918
Synonym: 'Antibiotic from Streptomyces albulus', 'MLS002702835', 'NSC-32743', 'CYCLOHEXIMIDE, 4-ACETOXY-(E-B)', 'Acetoxycycloheximide', 'E 73', 'Glutarimide, 3-2-(5-acetoxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl-', 'Acetyloxycycloheximide', '4-Acetoxycycloheximide', 'Cycloheximide, acetoxy-', 'AXM', 'MLSMR', 'SMR001566661'
IUPAC Name: [(1R,3S,5S)-3-[(1R)-2-(2,6-dioxopiperidin-4-yl)-1-hydroxyethyl]-1,5-dimethyl-4-oxocyclohexyl] acetate
Structure
SMILES: CC(=O)O[C@@]1(C)C[C@@H]([C@H](O)CC2CC(=O)N=C(O)C2)C(=O)[C@@H](C)C1
InChI: InChI=1S/C17H25NO6/c1-9-7-17(3,24-10(2)19)8-12(16(9)23)13(20)4-11-5-14(21)18-15(22)6-11/h9,11-13,20H,4-8H2,1-3H3,(H,18,21,22)/t9-,12-,13+,17+/m0/s1
InChIKey: UFDHNJJHPSGMFX-SQUSCZTCSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces pulveraceus | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 339.38800000000015
TPSA？: 113.26000000000002
MolLogP？: 1.5674999999999997
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | Monoamine oxidase A | Activity | None | None | 10.1021/jm800656v |
| Mus musculus | Monoamine oxidase B | Activity | None | None | 10.1021/jm800656v |