Lycopsamine
AlkaPlorer ID: AK002982
Synonym: None
IUPAC Name: [(7R,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
Structure
SMILES: CC(C)[C@](O)(C(=O)OCC1=CCN2CC[C@@H](O)[C@@H]12)[C@@H](C)O
InChI: InChI=1S/C15H25NO5/c1-9(2)15(20,10(3)17)14(19)21-8-11-4-6-16-7-5-12(18)13(11)16/h4,9-10,12-13,17-18,20H,5-8H2,1-3H3/t10-,12-,13-,15-/m1/s1
InChIKey: SFVVQRJOGUKCEG-BPGGGUHBSA-N
Reference
Pyrrolizidine alkaloids from critonia morifolia
PubChem CID: 44584035
LOTUS: LTS0105613
SuperNatural Ⅲ: SN0344363-01
NPASS: NPC279833
Source
Properties Information
Molecule Weight: 299.367
TPSA？: 90.23
MolLogP？: -0.3273000000000007
Number of H-Donors: 3
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leptinotarsa decemlineata | Leptinotarsa decemlineata | Activity | 12.0 | % | 10.1021/np980175a |
| Leptinotarsa decemlineata | Leptinotarsa decemlineata | Activity | 27.53 | % | 10.1021/np980175a |
| Leptinotarsa decemlineata | Leptinotarsa decemlineata | Activity | 68.4 | % | 10.1021/np980175a |
| Leptinotarsa decemlineata | Leptinotarsa decemlineata | EC50 | 25.97 | microg/cm2 | 10.1021/np980175a |
| Spodoptera littoralis | Spodoptera littoralis | Activity | 3.32 | mg | 10.1021/np980175a |
| Spodoptera littoralis | Spodoptera littoralis | Activity | 21.19 | mg | 10.1021/np980175a |
| Spodoptera littoralis | Spodoptera littoralis | Activity | 61.08 | % | 10.1021/np980175a |
| Spodoptera littoralis | Spodoptera littoralis | EC50 | 31.62 | microg/cm2 | 10.1021/np980175a |