8-Hydroxy-4-methoxy-1-methylquinolin-2-one
AlkaPlorer ID: AK003144
Synonym: None
IUPAC Name: 8-hydroxy-4-methoxy-1-methylquinolin-2-one
Structure
SMILES: CN1C(=O)C=C(C2=C1C(=CC=C2)O)OC
InChI: InChI=1S/C11H11NO3/c1-12-10(14)6-9(15-2)7-4-3-5-8(13)11(7)12/h3-6,13H,1-2H3
InChIKey: RVWQXFWAUMMLKE-UHFFFAOYSA-N
Reference
Alkaloids ofHaplophyllum foliosum. III. Structure of folidine
PubChem CID: 776146
CAS: 3148-23-0
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 205.213
TPSA？: 51.46000000000001
MolLogP？: 1.2526999999999995
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Giardia intestinalis | Putative fructose-1,6-bisphosphate aldolase | Potency | 3154.8 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 89125.1 | nM | None |
| Homo sapiens | Geminin | Potency | 73.1 | nM | None |
| Homo sapiens | Geminin | Potency | 6513.1 | nM | None |
| Homo sapiens | Microtubule-associated protein tau | Potency | 1778.3 | nM | None |
| Homo sapiens | Muscleblind-like protein 1 | Potency | 39810.7 | nM | None |
| Homo sapiens | Sentrin-specific protease 8 | IC50 | 11500.0 | nM | None |
| Homo sapiens | Sentrin-specific protease 8 | IC50 | 100000.0 | nM | None |