1,2-Dihydroxydibenz[cd,f]indol-4(5H)-one; O1,N-Di-Me
AlkaPlorer ID: AK003235
Synonym: Sauristolactam
IUPAC Name: 14-hydroxy-15-methoxy-10-methyl-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),2,4,6,8,12,14-heptaen-11-one
Structure
SMILES: COC1=C(O)C=C2C(=O)N(C)C3=C2C1=C1C=CC=CC1=C3
InChI: InChI=1S/C17H13NO3/c1-18-12-7-9-5-3-4-6-10(9)15-14(12)11(17(18)20)8-13(19)16(15)21-2/h3-8,19H,1-2H3
InChIKey: WRFZNTLPRUIGKH-UHFFFAOYSA-N
Reference
Chemistry of Saururus cernuus, V. Sauristolactam and Other Nitrogenous Constituents
PubChem CID: 131002
CAS: 128533-02-8
LOTUS: LTS0239522
SuperNatural Ⅲ: SN0417847
NPASS: NPC100573
COCONUT: CNP0298443
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Saururus chinensis | Saururus | Saururaceae | Piperales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Saururus cernuus | Saururus | Saururaceae | Piperales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Piper puberulum | Piper | Piperaceae | Piperales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 279.295
TPSA？: 49.77
MolLogP？: 3.297200000000002
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HCT-15 | GI50 | 4100.0 | nM | 10.1016/j.bmcl.2009.04.020 |
| None | NON-PROTEIN TARGET | GI50 | 4380.0 | nM | 10.1016/j.bmcl.2009.04.020 |
| None | NON-PROTEIN TARGET | GI50 | 23110.0 | nM | 10.1016/j.bmcl.2009.04.020 |
| None | NON-PROTEIN TARGET | GI50 | 23750.0 | nM | 10.1016/j.bmcl.2009.04.020 |