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name Structure Reference Source Properties Activities Metabolism

Norvaline

AlkaPlorer ID: AK003259

Synonym: None

IUPAC Name: (2S)-2-aminopentanoic acid

Structure

SMILES: CCC[C@H](N)C(=O)O

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InChI: InChI=1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

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InChIKey: SNDPXSYFESPGGJ-BYPYZUCNSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Serratia marcescens Serratia Yersiniaceae Enterobacterales Gammaproteobacteria Pseudomonadota None Bacteria

Properties Information

Molecule Weight: 117.14799999999998

TPSA？: 63.32000000000001

MolLogP？: 0.1983999999999999

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 0

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Proton-coupled amino acid transporter 1 Ki 46000000.0 nM 10.1016/j.bmc.2011.08.058
Homo sapiens Proton-coupled amino acid transporter 1 pKi -1.66 mM 10.1016/j.bmc.2011.08.058
Rattus norvegicus Amino acid transporter Inhibition 25.0 % None
None No relevant target LogP 1.9 None 10.1021/jm00393a031
None Unchecked krel 0.98 None 10.1016/s0960-894x(98)00164-4
None Unchecked Log 1/T 1.32 None 10.1021/jm00393a031

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT002026 CC(=O)C(=O)O.CCC[C@H](N)C(=O)O>>CCCC(=O)C(=O)O enzymemap_41544
AKRT002027 CC(=O)C(=O)O.CCC[C@H](N)C(=O)O>>CCC[C@H](N[C@H](C)C(=O)O)C(=O)O 1.5.1.28-RXN
AKRT005424 CC(C)CC(=O)C(=O)O.CCC[C@H](N)C(=O)O>>CC(C)C[C@H](N)C(=O)O.CCCC(=O)C(=O)O None
AKRT005820 CC(C)C[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_42198
AKRT006161 CC(C)[C@@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_86770
AKRT006326 CC(C)[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_86770
AKRT007348 CCCC(=O)C(=O)O.CCC[C@H](N)C(=O)O>>CC(C)CC(=O)C(=O)O enzymemap_42171
AKRT007349 CCCC(=O)C(=O)O.CCC[C@H](N)C(=O)O>>CC[C@H](C)[C@H](N)C(=O)O enzymemap_42171
AKRT007354 CCCC(=O)C(=O)O.C[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_41544
AKRT007358 CCCC(=O)C(=O)O.Nc1ccccc1C(=O)C[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O 66076
AKRT007362 CCCC(=O)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_21456
AKRT007468 CCCC(N)C#N>>CCC[C@H](N)C(=O)O 40779
AKRT007472 CCCC(NC(N)=O)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_77986
AKRT007473 CCCC(NC(N)=O)C(=O)O>>CCC[C@H](N)C(=O)O.O=C=O None
AKRT007503 CCCCC(=O)C(=O)O.CCC[C@H](N)C(=O)O>>CCCC(=O)C(=O)O.CCCC[C@H](N)C(=O)O None
AKRT009400 CCCCCC[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_42155
AKRT009506 CCCC[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_42154
AKRT009565 CCC[C@@H](N)C(=O)O>>CCC[C@H](N)C(=O)O None
AKRT009572 CCC[C@H](N)C(=O)Nc1ccc2c(C)cc(=O)oc2c1>>CCC[C@H](N)C(=O)O enzymemap_65503
AKRT009573 CCC[C@H](N)C(=O)Nc1ccc2c(C)cc(=O)oc2c1>>CCC[C@H](N)C(=O)O.Cc1cc(=O)oc2cc(N)ccc12 None
AKRT009574 CCC[C@H](N)C(=O)Nc1ccc2c(CC(N)=O)cc(=O)oc2c1>>CCC[C@H](N)C(=O)O enzymemap_65343
AKRT009575 CCC[C@H](N)C(=O)O.CC(C)CC(=O)C(=O)O>>CC(C)C[C@H](N)C(=O)O enzymemap_42164
AKRT009576 CCC[C@H](N)C(=O)O.CC(C)[C@H](C)C(=O)C(=O)O>>CC[C@@H](C)[C@H](N)C(=O)O enzymemap_42134
AKRT009577 CCC[C@H](N)C(=O)O.CC(C)[C@H](C)C(=O)C(=O)O>>CC[C@H](C)[C@H](N)C(=O)O enzymemap_42134
AKRT009578 CCC[C@H](N)C(=O)O.CCC(C)CC(=O)C(=O)O>>CCCC[C@H](N)C(=O)O enzymemap_42154
AKRT009579 CCC[C@H](N)C(=O)O.CCC(C)CC(=O)C(=O)O>>CC[C@H](C)[C@H](N)C(=O)O enzymemap_42154
AKRT009580 CCC[C@H](N)C(=O)O.CCCCC(=O)C(=O)O>>CCCC[C@H](N)C(=O)O enzymemap_42223
AKRT009581 CCC[C@H](N)C(=O)O.CCCCC(C)CC(=O)C(=O)O>>CCCCCC[C@H](N)C(=O)O enzymemap_42155
AKRT009582 CCC[C@H](N)C(=O)O.CCCCC(C)CC(=O)C(=O)O>>CC[C@H](C)[C@H](N)C(=O)O enzymemap_42155
AKRT009583 CCC[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O>>CCC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)O enzymemap_90555
AKRT009584 CCC[C@H](N)C(=O)O.O=C(O)C(=O)Cc1ccccc1>>CCCC(=O)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O None
AKRT009585 CCC[C@H](N)C(=O)O.O=C(O)CCC(=O)C(=O)O>>CCCC(=O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O None
AKRT009586 CCC[C@H](N)C(=O)O>>CC(C)[C@@H](N)C(=O)O enzymemap_86770
AKRT009587 CCC[C@H](N)C(=O)O>>CC(C)[C@H](N)C(=O)O enzymemap_86770
AKRT009588 CCC[C@H](N)C(=O)O>>CCCC(=O)C(=O)O 37035
AKRT009589 CCC[C@H](N)C(=O)O>>CCCCN enzymemap_81532
AKRT009590 CCC[C@H](N)C(=O)O>>CCC[C@@H](N)C(=O)O None
AKRT009591 CCC[C@H](N)C(=O)O>>CC[C@H](N)C(=O)O enzymemap_42171
AKRT009592 CCC[C@H](N)C(=O)O>>C[C@H](N)C(=O)O enzymemap_41544
AKRT009593 CCC[C@H](N)C(=O)O>>C[C@H](O)C[C@H](N)C(=O)O enzymemap_10922
AKRT009594 CCC[C@H](N)C(=O)O>>O=C=O enzymemap_81532
AKRT009597 CCC[C@H](N)C(N)=O>>CCC[C@H](N)C(=O)O enzymemap_64918
AKRT009598 CCC[C@H](N=C(O)CC[C@H](N)C(=O)O)C(=O)O>>CCC[C@H](N)C(=O)O MNXR133282
AKRT009600 CCC[C@H](NC(C)=O)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_76582
AKRT009601 CCC[C@H](N[C@H](C)C(=O)O)C(=O)O>>CCC[C@H](N)C(=O)O 1.5.1.28-RXN
AKRT009820 CC[C@@H](C)[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_42134
AKRT010019 CC[C@H](C)[C@H](N)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_42134
AKRT010174 CC[C@H](N)C(=O)O.CC(C)CC(=O)C(=O)O>>CCC[C@H](N)C(=O)O enzymemap_42171