Chrokaramine B
AlkaPlorer ID: AK003315
Synonym: None
IUPAC Name: (1Z,4R,5S,14S,15R,16R,19Z)-26-chloro-11,14,16-trihydroxy-15-methoxy-5,6,6,21,21-pentamethyl-3,7,18,23-tetrazaoctacyclo[16.13.0.03,16.04,7.04,14.08,13.022,30.024,29]hentriaconta-1(31),8(13),9,11,19,22(30),24(29),25,27-nonaene-2,17-dione
Structure
SMILES: C[C@@H]1[C@]23[C@]([C@H]([C@@]4(N2C(=O)/C/5=C/C6=C(C(/C=C\N5C4=O)(C)C)NC7=C6C=CC(=C7)Cl)O)OC)(C8=C(N3C1(C)C)C=CC(=C8)O)O
InChI: InChI=1S/C33H33ClN4O6/c1-16-30(4,5)37-23-10-8-18(39)14-21(23)31(42)27(44-6)32(43)28(41)36-12-11-29(2,3)25-20(19-9-7-17(34)13-22(19)35-25)15-24(36)26(40)38(32)33(16,31)37/h7-16,27,35,39,42-43H,1-6H3/b12-11-,24-15-/t16-,27+,31+,32+,33+/m0/s1
InChIKey: XQVGRZKJRYIIAE-QHUWKWKGSA-N
Reference
PubChem CID: 168288733
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Chrysosporium undulatum | Chrysosporium | Onygenaceae | Onygenales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 617.1020000000003
TPSA？: 129.57
MolLogP？: 3.8931000000000036
Number of H-Donors: 4
Number of H-Acceptors: 7
RingCount: 8
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | nan | None | 10.1021/acs.jnatprod.2c00445 |
| Bombyx mori | Bombyx mori | LD50 | 0.61 | mg.kg-1 | 10.1021/acs.jnatprod.2c00445 |
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/acs.jnatprod.2c00445 |
| Helicoverpa armigera | Helicoverpa armigera | LD50 | 0.06 | mg.kg-1 | 10.1021/acs.jnatprod.2c00445 |