6-deoxyaflaquinolone D
AlkaPlorer ID: AK003333
Synonym: None
IUPAC Name: (3S,4S)-4-hydroxy-3-methoxy-4-phenyl-1,3-dihydroquinolin-2-one
Structure
SMILES: CO[C@@H]1C(=O)NC2=CC=CC=C2[C@@]1(O)C1=CC=CC=C1
InChI: InChI=1S/C16H15NO3/c1-20-14-15(18)17-13-10-6-5-9-12(13)16(14,19)11-7-3-2-4-8-11/h2-10,14,19H,1H3,(H,17,18)/t14-,16+/m1/s1
InChIKey: ZJKJPVOOYVJWFU-ZBFHGGJFSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Aspergillus nidulans | Aspergillus | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 269.3
TPSA？: 58.56
MolLogP？: 1.8896
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | Activity | None | None | 10.1021/np4004646 |
| Homo sapiens | Bel-7402 | Activity | None | None | 10.1021/np4004646 |
| Homo sapiens | HL-60 | Activity | None | None | 10.1021/np4004646 |
| Homo sapiens | K562 | Activity | None | None | 10.1021/np4004646 |
| Homo sapiens | MDA-MB-231 | Activity | None | None | 10.1021/np4004646 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | None | None | 10.1021/np4004646 |