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Erythromycin

AlkaPlorer ID: AK003374

Synonym: None

IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

Structure

SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

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InChI: InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

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InChIKey: ULGZDMOVFRHVEP-RWJQBGPGSA-N

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Properties Information

Molecule Weight: 733.9370000000002

TPSA？: 193.91

MolLogP？: 1.785600000000004

Number of H-Donors: 5

Number of H-Acceptors: 14

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acholeplasma laidlawii Acholeplasma laidlawii IZ 28.0 mm 10.1021/acs.jnatprod.8b00200
Acinetobacter baumannii Acinetobacter baumannii Activity 25.0 uM 10.1016/j.bmc.2019.04.004
Acinetobacter baumannii Acinetobacter baumannii MBC 16.0 ug ml-1 10.1016/j.ejmech.2019.04.063
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1016/j.ejmech.2019.111850
Acinetobacter baumannii Acinetobacter baumannii MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b01780
Acinetobacter baumannii Acinetobacter baumannii MIC 1.5 ug.mL-1 10.1128/aac.00584-09
Acinetobacter baumannii Acinetobacter baumannii MIC 1.5 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 3.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 4.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1016/j.ejmech.2019.04.063
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 8.0 ug.mL-1 10.1128/aac.00748-09
Acinetobacter baumannii Acinetobacter baumannii MIC 12.0 ug.mL-1 10.1128/aac.00732-07
Acinetobacter baumannii Acinetobacter baumannii MIC 12.5 ug.mL-1 10.1021/acs.jnatprod.0c01212
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Acinetobacter baumannii Acinetobacter baumannii MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Acinetobacter baumannii Acinetobacter baumannii MIC 32.0 ug.mL-1 10.1128/aac.00748-09
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1128/aac.00748-09
Acinetobacter baumannii Acinetobacter baumannii MIC 4000.0 nM 10.1016/j.bmc.2019.03.034
Acinetobacter baumannii Acinetobacter baumannii MIC 8500.0 nM 10.1021/acs.jnatprod.1c00232
Acinetobacter baumannii Acinetobacter baumannii MIC 16000.0 nM 10.1016/j.bmc.2019.03.034
Acinetobacter baumannii Acinetobacter baumannii MIC 20000.0 nM 10.6019/CHEMBL4513161
Acinetobacter baumannii Acinetobacter baumannii MIC 128000.0 nM 10.1021/acs.jmedchem.9b00288
Acinetobacter baumannii Acinetobacter baumannii MIC 200000.0 nM 10.1016/j.bmc.2019.04.004
Acinetobacter baumannii Acinetobacter baumannii MIC 200000.0 nM 10.1016/j.ejmech.2019.111708
Acinetobacter baumannii Acinetobacter baumannii MIC nan None 10.1016/j.ejmech.2018.06.023
Acinetobacter baumannii Acinetobacter baumannii Ratio 8.0 None 10.1128/aac.00748-09
Acinetobacter calcoaceticus Acinetobacter calcoaceticus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Anaerococcus prevotii Anaerococcus prevotii MIC 82.0 ug.mL-1 10.1021/jm00403a025
Aspergillus niger Aspergillus niger IZ nan None 10.1021/acs.jnatprod.8b00200
Bacillus Bacillus MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Bacillus Bacillus MIC 0.39 ug.mL-1 10.1021/np030131o
Bacillus Bacillus MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Bacillus Bacillus MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Bacillus anthracis Bacillus anthracis MIC 0.25 ug.mL-1 10.1021/acs.jnatprod.0c01309
Bacillus anthracis Bacillus anthracis MIC 31.0 ug.mL-1 10.1016/j.ejmech.2019.04.043
Bacillus anthracis Bacillus anthracis MIC90 1.5 ug.mL-1 10.1039/C0MD00119H
Bacillus cereus Bacillus cereus Activity nan None 10.1021/acs.jmedchem.1c01905
Bacillus cereus Bacillus cereus IZ 19.0 mm 10.1007/s00044-009-9177-9
Bacillus cereus Bacillus cereus IZ 26.0 mm 10.1016/j.ejmech.2014.05.084
Bacillus cereus Bacillus cereus MIC 0.1 ug.mL-1 10.1021/jm00394a001
Bacillus pumilus Bacillus pumilus IZ 32.0 mm 10.1016/j.ejmech.2016.06.051
Bacillus pumilus Bacillus pumilus MIC 0.125 ug.mL-1 10.1016/j.bmc.2019.06.010
Bacillus pumilus Bacillus pumilus MIC 0.125 ug.mL-1 10.1016/j.bmc.2020.115729
Bacillus spizizenii Bacillus spizizenii IZ nan None 10.1021/acs.jnatprod.8b00200
Bacillus spizizenii Bacillus spizizenii MIC 0.2 ug.mL-1 10.1021/jm00215a025
Bacillus subtilis Bacillus subtilis IC50 0.19 ug.mL-1 10.1016/j.bmcl.2015.03.034
Bacillus subtilis Bacillus subtilis IC50 420.0 nM 10.1016/j.bmcl.2015.05.041
Bacillus subtilis Bacillus subtilis IZ 12.0 mm 10.1016/j.bmcl.2012.07.059
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1016/j.ejmech.2014.05.084
Bacillus subtilis Bacillus subtilis IZ 27.12 mm 10.1007/s00044-013-0755-5
Bacillus subtilis Bacillus subtilis IZ 30.0 mm 10.1016/j.ejmech.2010.04.020
Bacillus subtilis Bacillus subtilis IZ 31.0 mm 10.1021/np070195p
Bacillus subtilis Bacillus subtilis IZ 40.0 mm 10.1016/j.ejmech.2016.06.051
Bacillus subtilis Bacillus subtilis MIC 0.1 ug.mL-1 10.1016/j.bmcl.2006.08.130
Bacillus subtilis Bacillus subtilis MIC 0.1 ug.mL-1 10.1021/jm00394a001
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1007/s00044-011-9951-3
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1016/j.bmc.2019.06.010
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1016/j.bmc.2020.115729
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1021/np400742p
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1128/aac.00801-08
Bacillus subtilis Bacillus subtilis MIC 0.39 ug.mL-1 10.1021/np030131o
Bacillus subtilis Bacillus subtilis MIC 1.0 ug.mL-1 10.1021/np300554f
Bacillus subtilis Bacillus subtilis MIC 40.0 nM 10.1021/jm101593u
Bacillus subtilis Bacillus subtilis MIC 300.0 nM 10.1016/j.bmc.2016.04.058
Bacillus subtilis Bacillus subtilis MIC 390.0 nM 10.1016/0960-894X(95)00122-A
Bacillus thuringiensis Bacillus thuringiensis IZ 28.0 mm 10.1016/j.ejmech.2014.05.084
Bacillus thuringiensis Bacillus thuringiensis MIC 1.0 ug.mL-1 10.1021/np300554f
Bacteria Bacterial 70S ribosome IC50 170.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome IC50 750.0 nM 10.1021/jm00215a025
Bacteria Bacterial 70S ribosome IC50 760.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome IC50 1900.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome IC50 2200.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome IC50 87000.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome Inhibition 52.0 % 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome Inhibition nan % 10.1128/aac.01425-08
Bacteria Bacterial 70S ribosome Kd 11.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome Kd 15.0 nM 10.1128/aac.01425-08
Bacteria Bacterial 70S ribosome Kd 29.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome Kd 2100.0 nM 10.1128/aac.00672-07
Bacteria Bacterial 70S ribosome pK50 6.1 None 10.1021/jm00215a025
Bacteroides fragilis Bacteroides fragilis MIC 1.0 ug.mL-1 10.1021/jm00403a025
Bacteroides fragilis Bacteroides fragilis MIC 2.0 ug.mL-1 10.1021/jm00403a025
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1021/jm00403a025
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 1.0 ug.mL-1 10.1021/jm00403a025
Benjaminiella poitrasii Benjaminiella poitrasii MIC nan None 10.1016/j.bmcl.2008.09.013
Bifidobacterium bifidum Bifidobacterium bifidum MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 1.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 3.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 7.8 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 15.6 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 500.0 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium breve Bifidobacterium breve MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium breve Bifidobacterium breve MIC 1.95 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium breve Bifidobacterium breve MIC 3.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium longum Bifidobacterium longum MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium longum Bifidobacterium longum MIC 1.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium longum Bifidobacterium longum MIC 3.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium thermophilum Bifidobacterium thermophilum MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium thermophilum Bifidobacterium thermophilum MIC 3.9 ug.mL-1 10.1128/aac.00261-06
Bos taurus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Bos taurus Monoamine oxidase B Activity nan None 10.1021/jm800656v
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Burkholderia cepacia Burkholderia cepacia MIC nan None 10.1039/C0MD00251H
Burkholderia pseudomallei Burkholderia pseudomallei Activity nan None 10.1128/aac.01033-06
Burkholderia pseudomallei Burkholderia pseudomallei MIC 0.25 ug.mL-1 10.1128/aac.01033-06
Burkholderia pseudomallei Burkholderia pseudomallei MIC 0.5 ug.mL-1 10.1128/aac.01803-09
Burkholderia pseudomallei Burkholderia pseudomallei MIC 2.0 ug.mL-1 10.1128/aac.01803-09
Burkholderia pseudomallei Burkholderia pseudomallei MIC 4.0 ug.mL-1 10.1128/aac.01803-09
Burkholderia pseudomallei Burkholderia pseudomallei MIC 8.0 ug.mL-1 10.1128/aac.01033-06
Burkholderia pseudomallei Burkholderia pseudomallei MIC 8.0 ug.mL-1 10.1128/aac.01803-09
Burkholderia pseudomallei Burkholderia pseudomallei MIC 16.0 ug.mL-1 10.1128/aac.01803-09
Burkholderia pseudomallei Burkholderia pseudomallei MIC 32.0 ug.mL-1 10.1128/aac.01033-06
Burkholderia pseudomallei Burkholderia pseudomallei MIC 32.0 ug.mL-1 10.1128/aac.01803-09
Burkholderia pseudomallei Burkholderia pseudomallei MIC 64.0 ug.mL-1 10.1128/aac.01033-06
Burkholderia pseudomallei Burkholderia pseudomallei MIC 128.0 ug.mL-1 10.1128/aac.01033-06
Burkholderia pseudomallei Burkholderia pseudomallei MIC 128.0 ug.mL-1 10.1128/aac.01803-09
Campylobacter coli Campylobacter coli Activity 0.0 % 10.1128/aac.01260-08
Campylobacter coli Campylobacter coli Activity 50.0 % 10.1128/aac.00898-09
Campylobacter coli Campylobacter coli Activity 100.0 % 10.1128/aac.01260-08
Campylobacter coli Campylobacter coli Activity nan None 10.1128/aac.01411-06
Campylobacter coli Campylobacter coli IZ 15.0 mm 10.1128/aac.00767-08
Campylobacter coli Campylobacter coli MIC 0.06 ug.mL-1 10.1128/aac.01260-08
Campylobacter coli Campylobacter coli MIC 0.125 ug.mL-1 10.1128/aac.01411-06
Campylobacter coli Campylobacter coli MIC 2.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter coli Campylobacter coli MIC 8.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter coli Campylobacter coli MIC 32.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter coli Campylobacter coli MIC50 0.25 ug.mL-1 10.1128/aac.01260-08
Campylobacter coli Campylobacter coli MIC90 0.5 ug.mL-1 10.1128/aac.01260-08
Campylobacter jejuni Campylobacter jejuni Activity 0.0 % 10.1128/aac.01260-08
Campylobacter jejuni Campylobacter jejuni Activity 4.5 % 10.1128/aac.00898-09
Campylobacter jejuni Campylobacter jejuni Activity 100.0 % 10.1128/aac.01260-08
Campylobacter jejuni Campylobacter jejuni Activity nan None 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni FC 8.0 None 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni FC 64.0 None 10.1128/aac.01592-06
Campylobacter jejuni Campylobacter jejuni FC 128.0 None 10.1128/aac.01592-06
Campylobacter jejuni Campylobacter jejuni IZ 6.0 mm 10.1128/aac.00905-06
Campylobacter jejuni Campylobacter jejuni IZ 17.5 mm 10.1128/aac.00905-06
Campylobacter jejuni Campylobacter jejuni MIC 0.06 ug.mL-1 10.1128/aac.00905-06
Campylobacter jejuni Campylobacter jejuni MIC 0.06 ug.mL-1 10.1128/aac.01260-08
Campylobacter jejuni Campylobacter jejuni MIC 0.125 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 0.25 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 1.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 1.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 2.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 4.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 4.0 ug.mL-1 10.1128/aac.01592-06
Campylobacter jejuni Campylobacter jejuni MIC 8.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 8.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 8.0 ug.mL-1 10.1128/aac.01592-06
Campylobacter jejuni Campylobacter jejuni MIC 16.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 16.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 32.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 32.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 64.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 128.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 128.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 256.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 256.0 ug.mL-1 10.1128/aac.00905-06
Campylobacter jejuni Campylobacter jejuni MIC 256.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 256.0 ug.mL-1 10.1128/aac.01592-06
Campylobacter jejuni Campylobacter jejuni MIC 512.0 ug.mL-1 10.1128/aac.00450-08
Campylobacter jejuni Campylobacter jejuni MIC 512.0 ug.mL-1 10.1128/aac.01411-06
Campylobacter jejuni Campylobacter jejuni MIC 1024.0 ug.mL-1 10.1128/aac.01592-06
Campylobacter jejuni Campylobacter jejuni MIC50 0.25 ug.mL-1 10.1128/aac.01260-08
Campylobacter jejuni Campylobacter jejuni MIC90 0.5 ug.mL-1 10.1128/aac.01260-08
Candida albicans Candida albicans IZ nan None 10.1021/acs.jnatprod.8b00200
Candida albicans Candida albicans MIC 32.0 ug.mL-1 10.1021/np800783b
Candida albicans Candida albicans MIC 20000.0 nM 10.6019/CHEMBL4513161
Candida albicans Candida albicans MIC nan None 10.1016/j.bmcl.2008.09.013
Canis lupus familiaris Canis familiaris CL 2.376 mL.min-1.kg-1 10.1124/dmd.112.049312
Canis lupus familiaris Canis familiaris CL 4.483 mL.min-1.kg-1 10.1124/dmd.112.049312
Canis lupus familiaris Canis familiaris GMS activity 1.0 None 10.1021/jm00394a001
Canis lupus familiaris Canis familiaris MI100 32.3 ug kg-1 10.1016/0960-894X(95)00122-A
Canis lupus familiaris MDCK Ratio 8.5 None 10.1124/dmd.110.034629
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chlamydia pneumoniae Chlamydia pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01383-07
Chlamydia pneumoniae Chlamydia pneumoniae MIC 170.0 nM 10.1021/jm1008083
Chlamydia psittaci 6BC Chlamydia psittaci 6BC MIC 0.2 ug.mL-1 10.1128/aac.00962-07
Chlamydia psittaci 6BC Chlamydia psittaci 6BC MIC 20.0 ug.mL-1 10.1128/aac.00962-07
Chlamydia psittaci 6BC Chlamydia psittaci 6BC MIC 200.0 ug.mL-1 10.1128/aac.00962-07
Chlamydia trachomatis Chlamydia trachomatis MBC 1.0 ug ml-1 10.1128/aac.00553-10
Chlamydia trachomatis Chlamydia trachomatis MBC 2.0 ug ml-1 10.1128/aac.00553-10
Chlamydia trachomatis Chlamydia trachomatis MIC 0.0 ug.mL-1 10.1021/jm00403a025
Chlamydia trachomatis Chlamydia trachomatis MIC 0.12 ug.mL-1 10.1128/aac.01383-07
Chlamydia trachomatis Chlamydia trachomatis MIC 0.2 ug.mL-1 10.1128/aac.00962-07
Chlamydia trachomatis Chlamydia trachomatis MIC 0.25 ug.mL-1 10.1128/aac.01383-07
Chlamydia trachomatis Chlamydia trachomatis MIC 0.5 ug.mL-1 10.1128/aac.00553-10
Chlamydia trachomatis Chlamydia trachomatis MIC 0.8 ug.mL-1 10.1128/aac.00962-07
Chlamydia trachomatis Chlamydia trachomatis MIC 1.0 ug.mL-1 10.1128/aac.00553-10
Chlorocebus sabaeus Vero CC50 nan None 10.1016/j.bmcl.2019.03.038
Clostridioides difficile Clostridioides difficile MIC 0.5 ug.mL-1 10.1021/jm00403a025
Clostridium perfringens Clostridium perfringens Activity nan None 10.1128/aac.01208-09
Clostridium perfringens Clostridium perfringens MIC 0.5 ug.mL-1 10.1021/jm00403a025
Clostridium septicum Clostridium septicum MIC 0.5 ug.mL-1 10.1021/jm00403a025
Collinsella aerofaciens Collinsella aerofaciens MIC 0.5 ug.mL-1 10.1021/jm00403a025
Corynebacterium amycolatum Corynebacterium amycolatum MIC 1.47 ug.mL-1 10.1128/aac.00062-07
Corynebacterium diphtheriae Corynebacterium diphtheriae MIC 1.47 ug.mL-1 10.1128/aac.00062-07
Corynebacterium jeikeium Corynebacterium jeikeium MIC 1.47 ug.mL-1 10.1128/aac.00062-07
Corynebacterium minutissimum Corynebacterium minutissimum MIC 1.47 ug.mL-1 10.1128/aac.00062-07
Cricetulus griseus CHO Log CR 0.7 None 10.1021/jm00169a014
Cryptococcus neoformans Cryptococcus neoformans MIC 20000.0 nM 10.6019/CHEMBL4513161
Cryptococcus neoformans Cryptococcus neoformans MIC nan None 10.1016/j.bmcl.2008.09.013
Cutibacterium acnes Cutibacterium acnes MBC 0.125 ug ml-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MBC 32.0 ug ml-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 0.06 ug.mL-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 0.06 ug.mL-1 10.1128/aac.00672-07
Cutibacterium acnes Cutibacterium acnes MIC 0.1 ug.mL-1 10.1016/j.bmcl.2006.08.130
Cutibacterium acnes Cutibacterium acnes MIC 0.125 ug.mL-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 0.5 ug.mL-1 10.1021/jm00403a025
Cutibacterium acnes Cutibacterium acnes MIC 0.5 ug.mL-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 1.0 ug.mL-1 10.1128/aac.00672-07
Cutibacterium acnes Cutibacterium acnes MIC 2.0 ug.mL-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 4.0 ug.mL-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 4.0 ug.mL-1 10.1128/aac.00672-07
Cutibacterium acnes Cutibacterium acnes MIC 128.0 ug.mL-1 10.1128/aac.00672-07
Cutibacterium acnes Cutibacterium acnes MIC 512.0 ug.mL-1 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes MIC 512.0 ug.mL-1 10.1128/aac.00672-07
Cutibacterium acnes Cutibacterium acnes MIC50 1.0 ug.mL-1 10.1016/j.bmc.2013.06.027
Cutibacterium acnes Cutibacterium acnes MIC90 1.0 ug.mL-1 10.1016/j.bmc.2013.06.027
Cutibacterium acnes Cutibacterium acnes Ratio 2.0 None 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes Ratio 8.0 None 10.1128/aac.00062-07
Cutibacterium acnes Cutibacterium acnes Ratio 533.0 None 10.1128/aac.00062-07
Dialister invisus Dialister invisus Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister invisus Dialister invisus Activity nan None 10.1128/aac.00538-07
Dialister invisus Dialister invisus MIC nan None 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus Activity nan None 10.1128/aac.00538-07
Dialister micraerophilus Dialister micraerophilus MIC 0.125 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes Activity nan None 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC 0.125 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC50 1.0 ug.mL-1 10.1128/aac.00538-07
Dialister pneumosintes Dialister pneumosintes MIC90 2.0 ug.mL-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity 1.0 ug ml-1 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens Activity nan None 10.1128/aac.00538-07
Dialister propionicifaciens Dialister propionicifaciens MIC 0.125 ug.mL-1 10.1128/aac.00538-07
Eikenella corrodens Eikenella corrodens MIC 1.0 ug.mL-1 10.1021/jm00403a025
Enterobacter cloacae Enterobacter cloacae MIC 0.094 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 0.375 ug.mL-1 10.1128/aac.00405-08
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Enterobacter cloacae Enterobacter cloacae MIC 1.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 1.5 ug.mL-1 10.1128/aac.00405-08
Enterobacter cloacae Enterobacter cloacae MIC 8.0 ug.mL-1 10.1128/aac.00405-08
Enterobacter cloacae Enterobacter cloacae MIC 12.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 16.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1016/S0960-894X(00)80333-9
Enterobacter cloacae Enterobacter cloacae MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Enterobacter cloacae Enterobacter cloacae MIC 48.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 48.0 ug.mL-1 10.1128/aac.00405-08
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1128/aac.00405-08
Enterobacter cloacae Enterobacter cloacae MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Enterobacter cloacae Enterobacter cloacae MIC 128.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 256.0 ug.mL-1 10.1128/aac.00072-07
Enterobacter cloacae Enterobacter cloacae MIC 1000.0 nM 10.1016/j.bmc.2019.03.034
Enterobacter cloacae Enterobacter cloacae MIC 64000.0 nM 10.1016/j.bmc.2019.03.034
Enterobacter cloacae Enterobacter cloacae Ratio 21.0 None 10.1128/aac.00405-08
Enterococcus Enterococcus MBC 64.0 ug ml-1 10.1016/j.ejmech.2011.12.039
Enterococcus Enterococcus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.12.039
Enterococcus Enterococcus MIC 64.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus Enterococcus MIC50 2.5 ug.mL-1 10.1021/jm980240d
Enterococcus Enterococcus MIC50 40.0 ug.mL-1 10.1021/jm980240d
Enterococcus Enterococcus MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus Enterococcus MIC90 10.0 ug.mL-1 10.1021/jm980240d
Enterococcus Enterococcus MIC90 40.0 ug.mL-1 10.1021/jm980240d
Enterococcus Enterococcus MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus avium Enterococcus avium MIC 8.0 ug.mL-1 10.1128/aac.00908-07
Enterococcus faecalis Enterococcus faecalis Activity 0.0 % 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis Activity 10.2 % 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis Activity 13.5 % 10.1128/aac.00129-09
Enterococcus faecalis Enterococcus faecalis Activity 52.9 % 10.1128/aac.00129-09
Enterococcus faecalis Enterococcus faecalis Activity 59.9 % 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis Activity 96.0 % 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1016/j.bmcl.2006.08.076
Enterococcus faecalis Enterococcus faecalis Activity nan None 10.1128/aac.01325-07
Enterococcus faecalis Enterococcus faecalis DIZ nan None 10.1016/j.ejmech.2014.05.084
Enterococcus faecalis Enterococcus faecalis IZ 20.0 mm 10.1016/j.bmc.2019.115097
Enterococcus faecalis Enterococcus faecalis MBC50 32.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MBC90 128.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MBC90 256.0 mg/L 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC 0.06 ug.mL-1 10.1021/jm00173a028
Enterococcus faecalis Enterococcus faecalis MIC 0.12 ug.mL-1 10.1128/aac.00129-09
Enterococcus faecalis Enterococcus faecalis MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC 0.12 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecalis Enterococcus faecalis MIC 0.125 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecalis Enterococcus faecalis MIC 0.125 ug.mL-1 10.1128/aac.00754-08
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1128/aac.00481-08
Enterococcus faecalis Enterococcus faecalis MIC 0.25 ug.mL-1 10.1128/aac.00754-08
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.bmc.2016.06.044
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.08.123
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.bmcl.2012.09.097
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.bmcl.2013.06.048
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2012.12.027
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/S0960-894X(00)80333-9
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/S0960-894X(01)80238-9
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1021/jm3012728
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1021/np800783b
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00230-08
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00801-08
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2008.07.007
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2008.09.019
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1021/jm8000136
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1128/aac.00603-06
Enterococcus faecalis Enterococcus faecalis MIC 3.13 ug.mL-1 10.1021/jm015566s
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1021/np4006794
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1128/aac.00230-08
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1128/aac.00576-06
Enterococcus faecalis Enterococcus faecalis MIC 8.0 ug.mL-1 10.1128/aac.00908-07
Enterococcus faecalis Enterococcus faecalis MIC 12.5 ug.mL-1 10.1016/j.bmcl.2005.11.061
Enterococcus faecalis Enterococcus faecalis MIC 16.0 ug.mL-1 10.1016/j.bmcl.2004.12.067
Enterococcus faecalis Enterococcus faecalis MIC 16.0 ug.mL-1 10.1021/np4006794
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1021/np4006794
Enterococcus faecalis Enterococcus faecalis MIC 32.0 ug.mL-1 10.1021/np800783b
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.08.123
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.09.097
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2013.06.048
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1016/j.ejmech.2012.12.027
Enterococcus faecalis Enterococcus faecalis MIC 64.0 ug.mL-1 10.1021/jm3012728
Enterococcus faecalis Enterococcus faecalis MIC 256.0 ug.mL-1 10.1016/j.bmcl.2007.08.068
Enterococcus faecalis Enterococcus faecalis MIC 256.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Enterococcus faecalis Enterococcus faecalis MIC 1024.0 ug.mL-1 10.1128/aac.00754-08
Enterococcus faecalis Enterococcus faecalis MIC nan None 10.1021/np4006794
Enterococcus faecalis Enterococcus faecalis MIC50 4.0 ug.mL-1 10.1128/aac.00129-09
Enterococcus faecalis Enterococcus faecalis MIC50 8.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC50 8.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecalis Enterococcus faecalis MIC50 8.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC50 16.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecalis Enterococcus faecalis MIC=>90 1.0 ug ml-1 10.1016/j.bmcl.2013.02.016
Enterococcus faecalis Enterococcus faecalis MIC=>90 64.0 ug ml-1 10.1016/j.bmcl.2013.02.016
Enterococcus faecalis Enterococcus faecalis MIC>90 1.9 ug ml-1 10.1021/np400145u
Enterococcus faecalis Enterococcus faecalis MIC90 1.0 ug.mL-1 10.1016/j.bmc.2012.10.009
Enterococcus faecalis Enterococcus faecalis MIC90 4.0 ug.mL-1 10.1128/aac.00129-09
Enterococcus faecalis Enterococcus faecalis MIC90 8.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecalis Enterococcus faecalis MIC90 32.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC90 64.0 ug.mL-1 10.1016/j.bmc.2012.10.009
Enterococcus faecalis Enterococcus faecalis MIC90 64.0 ug.mL-1 10.1128/aac.00344-06
Enterococcus faecalis Enterococcus faecalis MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium Activity 0.0 % 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium Activity 3.0 % 10.1128/aac.00129-09
Enterococcus faecium Enterococcus faecium Activity 84.5 % 10.1128/aac.00129-09
Enterococcus faecium Enterococcus faecium Activity 92.3 % 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium Activity nan None 10.1021/acs.jmedchem.1c01905
Enterococcus faecium Enterococcus faecium Activity nan None 10.1128/aac.01325-07
Enterococcus faecium Enterococcus faecium IZ 6.0 mm 10.1016/j.bmc.2019.115097
Enterococcus faecium Enterococcus faecium MIC 0.05 ug.mL-1 10.1016/j.bmcl.2003.12.059
Enterococcus faecium Enterococcus faecium MIC 0.1 ug.mL-1 10.1128/aac.00798-09
Enterococcus faecium Enterococcus faecium MIC 0.12 ug.mL-1 10.1128/aac.00129-09
Enterococcus faecium Enterococcus faecium MIC 0.125 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium MIC 0.25 ug.mL-1 10.1128/aac.00242-09
Enterococcus faecium Enterococcus faecium MIC 0.5 ug.mL-1 10.1128/aac.00242-09
Enterococcus faecium Enterococcus faecium MIC 1.0 ug.mL-1 10.1021/jm8000136
Enterococcus faecium Enterococcus faecium MIC 1.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecium Enterococcus faecium MIC 1.0 ug.mL-1 10.1128/aac.00798-09
Enterococcus faecium Enterococcus faecium MIC 1.56 ug.mL-1 10.1021/jm015566s
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Enterococcus faecium Enterococcus faecium MIC 2.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC 8.0 ug.mL-1 10.1128/aac.00576-06
Enterococcus faecium Enterococcus faecium MIC 12.0 ug.mL-1 10.1016/j.bmcl.2019.03.038
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1021/np800783b
Enterococcus faecium Enterococcus faecium MIC 64.0 ug.mL-1 10.1021/np4006794
Enterococcus faecium Enterococcus faecium MIC 128.0 ug.mL-1 10.1021/jm8000136
Enterococcus faecium Enterococcus faecium MIC 256.0 ug.mL-1 10.1021/np4006794
Enterococcus faecium Enterococcus faecium MIC 256.0 ug.mL-1 10.1128/aac.00798-09
Enterococcus faecium Enterococcus faecium MIC 512.0 ug.mL-1 10.1128/aac.00242-09
Enterococcus faecium Enterococcus faecium MIC nan None 10.1016/j.bmc.2019.03.034
Enterococcus faecium Enterococcus faecium MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecium Enterococcus faecium MIC50 4.0 ug.mL-1 10.1128/aac.00129-09
Enterococcus faecium Enterococcus faecium MIC50 8.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Enterococcus faecium Enterococcus faecium MIC90 4.0 ug.mL-1 10.1128/aac.00129-09
Enterococcus faecium Enterococcus faecium MIC90 8.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Escherichia coli Escherichia coli Activity 50.0 uM 10.1016/j.bmc.2019.04.004
Escherichia coli Escherichia coli Activity 70.0 % 10.1128/aac.00870-08
Escherichia coli Escherichia coli Activity nan None 10.1016/j.bmcl.2018.11.038
Escherichia coli Escherichia coli Activity nan None 10.1021/acs.jmedchem.1c01905
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00870-08
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.01048-06
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.01266-07
Escherichia coli Escherichia coli AD50 nan None 10.1128/aac.01048-06
Escherichia coli Escherichia coli Antibiotic resistance nan None 10.1016/s0960-894x(98)00536-8
Escherichia coli Escherichia coli FICI 0.188 None 10.1128/aac.00405-08
Escherichia coli Escherichia coli GI nan None 10.1016/j.bmc.2016.04.058
Escherichia coli Escherichia coli IC50 0.31 ug.mL-1 10.1016/j.bmcl.2015.03.034
Escherichia coli Escherichia coli IC50 80.0 nM 10.1016/j.bmcl.2005.11.028
Escherichia coli Escherichia coli IC50 430.0 nM 10.1016/j.bmcl.2015.05.041
Escherichia coli Escherichia coli IC50 900.0 nM 10.1016/j.bmcl.2005.12.033
Escherichia coli Escherichia coli IC50 2120.0 nM 10.1021/acs.jmedchem.8b00790
Escherichia coli Escherichia coli Inhibition 30.0 % 10.1128/aac.00870-08
Escherichia coli Escherichia coli Inhibition 60.0 % 10.1128/aac.00870-08
Escherichia coli Escherichia coli Inhibition nan % 10.1128/aac.00870-08
Escherichia coli Escherichia coli IZ 11.0 mm 10.1007/s00044-009-9177-9
Escherichia coli Escherichia coli IZ 11.0 mm 10.1016/j.ejmech.2014.05.084
Escherichia coli Escherichia coli IZ 15.0 mm 10.1016/j.ejmech.2010.04.020
Escherichia coli Escherichia coli IZ 15.0 mm 10.1016/j.ejmech.2019.04.002
Escherichia coli Escherichia coli IZ 27.45 mm 10.1007/s00044-013-0755-5
Escherichia coli Escherichia coli IZ 37.0 mm 10.1016/j.ejmech.2016.06.051
Escherichia coli Escherichia coli IZ nan None 10.1021/acs.jnatprod.8b00200
Escherichia coli Escherichia coli MBC 2.0 ug ml-1 10.1016/j.ejmech.2019.04.063
Escherichia coli Escherichia coli MBC 64.0 ug ml-1 10.1016/j.ejmech.2019.04.063
Escherichia coli Escherichia coli MIC 0.05 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1021/np060334n
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 0.25 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 0.38 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1016/j.bmcl.2023.129331
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1021/jm301499r
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00454-09
Escherichia coli Escherichia coli MIC 0.75 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2018.06.023
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2019.04.063
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00339-07
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1128/aac.01052-07
Escherichia coli Escherichia coli MIC 1.9 ug.mL-1 10.1128/aac.00580-10
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2005.12.033
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmcl.2015.07.010
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00339-07
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1128/aac.00481-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1016/j.ejmech.2020.113049
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01048-06
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01126-09
Escherichia coli Escherichia coli MIC 5.0 ug.mL-1 10.1128/aac.00454-09
Escherichia coli Escherichia coli MIC 5.0 ug.mL-1 10.1128/aac.01168-09
Escherichia coli Escherichia coli MIC 6.0 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.bmcl.2023.129331
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01048-06
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1128/aac.01126-09
Escherichia coli Escherichia coli MIC 8.2 ug.mL-1 10.1128/aac.00580-10
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1021/jm00394a001
Escherichia coli Escherichia coli MIC 13.0 ug.mL-1 10.1021/acs.jmedchem.7b00204
Escherichia coli Escherichia coli MIC 15.63 ug.mL-1 10.1128/aac.00580-10
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.bmc.2019.06.010
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.bmc.2020.115729
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/S0960-894X(00)80333-9
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1021/acs.jnatprod.0c01309
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1021/jm400097h
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00748-09
Escherichia coli Escherichia coli MIC 25.0 ug.mL-1 10.1021/acs.jnatprod.0c01212
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.bmc.2016.06.044
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.bmcl.2008.07.007
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.07.010
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2018.06.023
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2019.04.063
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)80238-9
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/jm301499r
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/np300554f
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/np500775e
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00405-08
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01052-07
Escherichia coli Escherichia coli MIC 40.0 ug.mL-1 10.1021/jm980240d
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.09.013
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.01.040
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2019.02.003
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2023.129331
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1021/np300554f
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00481-08
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00944-09
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01052-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01472-06
Escherichia coli Escherichia coli MIC 125.0 nM 10.1016/j.bmcl.2023.129301
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1007/s00044-011-9951-3
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/np500775e
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1039/d2md00041e
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00339-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00672-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01048-06
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01052-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01126-09
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01425-08
Escherichia coli Escherichia coli MIC 150.0 ug.mL-1 10.1128/aac.00802-06
Escherichia coli Escherichia coli MIC 200.0 ug.mL-1 10.1128/aac.00802-06
Escherichia coli Escherichia coli MIC 250.0 ug.mL-1 10.1128/aac.00802-06
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1016/j.bmcl.2007.08.068
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1021/np4006794
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00944-09
Escherichia coli Escherichia coli MIC 300.0 ug.mL-1 10.1128/aac.01168-09
Escherichia coli Escherichia coli MIC 500.0 nM 10.1016/j.bmc.2019.03.034
Escherichia coli Escherichia coli MIC 500.0 ug.mL-1 10.1128/aac.01425-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC 512.0 ug.mL-1 10.1128/aac.01126-09
Escherichia coli Escherichia coli MIC 1000.0 nM 10.1016/j.bmc.2019.03.034
Escherichia coli Escherichia coli MIC 1024.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 2000.0 nM 10.1016/j.bmc.2019.03.034
Escherichia coli Escherichia coli MIC 2000.0 nM 10.1016/j.bmcl.2023.129301
Escherichia coli Escherichia coli MIC 2400.0 ug.mL-1 10.1128/aac.00802-06
Escherichia coli Escherichia coli MIC 3000.0 ug.mL-1 10.1128/aac.01266-07
Escherichia coli Escherichia coli MIC 4000.0 nM 10.1016/j.bmcl.2023.129301
Escherichia coli Escherichia coli MIC 20000.0 nM 10.6019/CHEMBL4513161
Escherichia coli Escherichia coli MIC 25000.0 ug.mL-1 10.1128/aac.01266-07
Escherichia coli Escherichia coli MIC 32000.0 nM 10.1021/acs.jmedchem.9b00288
Escherichia coli Escherichia coli MIC 64000.0 nM 10.1016/j.bmc.2019.03.034
Escherichia coli Escherichia coli MIC 64000.0 nM 10.1016/j.bmcl.2023.129301
Escherichia coli Escherichia coli MIC 64000.0 nM 10.1021/acs.jmedchem.9b00288
Escherichia coli Escherichia coli MIC 100000.0 nM 10.1016/0960-894X(95)00122-A
Escherichia coli Escherichia coli MIC 174000.0 nM 10.1016/j.bmc.2022.116762
Escherichia coli Escherichia coli MIC 200000.0 nM 10.1016/j.bmc.2016.04.058
Escherichia coli Escherichia coli MIC 200000.0 nM 10.1016/j.bmc.2019.04.004
Escherichia coli Escherichia coli MIC 200000.0 nM 10.1016/j.ejmech.2019.111708
Escherichia coli Escherichia coli MIC 700000.0 nM 10.1016/j.bmc.2016.04.058
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.00719-10
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.00921-08
Escherichia coli Escherichia coli MIC80 256.0 ug.mL-1 10.1016/j.bmcl.2013.07.042
Escherichia coli Escherichia coli MIC90 16.0 ug.mL-1 10.1016/j.bmcl.2009.11.042
Escherichia coli Escherichia coli MIC90 64.0 ug.mL-1 10.1016/j.ejmech.2011.05.032
Escherichia coli Escherichia coli Ratio 2.0 None 10.1128/aac.00339-07
Escherichia coli Escherichia coli Ratio 4.0 None 10.1128/aac.00921-08
Escherichia coli Escherichia coli Ratio 6.0 None 10.1128/aac.00748-09
Escherichia coli Escherichia coli Ratio 32.0 None 10.1128/aac.00405-08
Escherichia coli GroEL/GroES IC50 100000.0 nM 10.1016/j.bmcl.2019.02.028
Escherichia coli GroEL/GroES IC50 178000.0 nM 10.1016/j.bmcl.2019.02.028
Escherichia coli GroEL/GroES Inhibition 99.0 % 10.1016/j.bmcl.2019.02.028
Escherichia coli GroEL/GroES Inhibition 101.0 % 10.1016/j.bmcl.2019.02.028
Escherichia coli K-12 Beta-lactamase AmpC Potency 1995.3 nM None
Escherichia coli (strain K12) 60 kDa chaperonin IC50 250000.0 nM 10.1016/j.bmcl.2019.02.028
Escherichia coli (strain K12) tRNA (guanine-N(1)-)-methyltransferase IC50 nan None 10.1016/j.bmcl.2023.129331
Fusarium oxysporum Fusarium oxysporum MIC nan None 10.1016/j.bmcl.2008.09.013
Fusobacterium Fusobacterium MIC 2.0 ug.mL-1 10.1021/jm00403a025
Fusobacterium necrophorum Fusobacterium necrophorum MIC 2.0 ug.mL-1 10.1021/jm00403a025
Haemophilus Haemophilus MIC50 1.2 ug.mL-1 10.1021/jm980240d
Haemophilus Haemophilus MIC90 5.0 ug.mL-1 10.1021/jm980240d
Haemophilus Haemophilus MIC90 10.0 ug.mL-1 10.1021/jm980240d
Haemophilus influenzae Haemophilus influenzae Activity 32.5 % 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae Activity nan None 10.1128/aac.00607-07
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1016/j.ejmech.2010.09.060
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.9b01159
Haemophilus influenzae Haemophilus influenzae MIC 1.0 ug.mL-1 10.1021/jm00173a028
Haemophilus influenzae Haemophilus influenzae MIC 1.56 ug.mL-1 10.1016/j.bmcl.2005.11.061
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1016/j.bmc.2016.06.044
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1016/j.bmcl.2004.04.077
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1016/S0960-894X(00)80333-9
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1016/S0960-894X(01)80238-9
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1021/jm00403a025
Haemophilus influenzae Haemophilus influenzae MIC 2.0 ug.mL-1 10.1021/jm8000136
Haemophilus influenzae Haemophilus influenzae MIC 2.2 ug.mL-1 10.1039/C0MD00251H
Haemophilus influenzae Haemophilus influenzae MIC 2.5 ug.mL-1 10.1021/jm980240d
Haemophilus influenzae Haemophilus influenzae MIC 3.12 ug.mL-1 10.1016/j.bmcl.2005.11.061
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.bmc.2007.04.021
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2004.03.020
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2006.08.130
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2008.07.118
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2008.10.109
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2023.129331
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/j.ejmech.2010.09.060
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/s0960-894x(00)00106-2
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1021/jm00403a025
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1021/jm025580k
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1021/jm034233n
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1021/jm970548p
Haemophilus influenzae Haemophilus influenzae MIC 4.0 ug.mL-1 10.1039/C0MD00251H
Haemophilus influenzae Haemophilus influenzae MIC 6.25 ug.mL-1 10.1016/j.bmcl.2005.11.061
Haemophilus influenzae Haemophilus influenzae MIC 6.25 ug.mL-1 10.1021/jm015566s
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2004.12.067
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2005.03.011
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2005.10.074
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2005.12.097
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2006.09.036
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2007.04.104
Haemophilus influenzae Haemophilus influenzae MIC 8.0 ug.mL-1 10.1021/jm990618n
Haemophilus influenzae Haemophilus influenzae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2011.10.101
Haemophilus influenzae Haemophilus influenzae MIC 16.0 ug.mL-1 10.1016/j.ejmech.2010.05.009
Haemophilus influenzae Haemophilus influenzae MIC 64.0 ug.mL-1 10.1016/S0960-894X(00)80333-9
Haemophilus influenzae Haemophilus influenzae MIC 64.0 ug.mL-1 10.1021/np060334n
Haemophilus influenzae Haemophilus influenzae MIC 64.0 ug.mL-1 10.1128/aac.00723-10
Haemophilus influenzae Haemophilus influenzae MIC 4000.0 ug.mL-1 10.1021/jm970547x
Haemophilus influenzae Haemophilus influenzae MIC50 1.0 ug.mL-1 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Haemophilus influenzae Haemophilus influenzae MIC50 nan None 10.1128/aac.01017-06
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.01548-09
Haemophilus influenzae Haemophilus influenzae MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Haemophilus influenzae Haemophilus influenzae MIC90 nan None 10.1128/aac.01017-06
Haemophilus parainfluenzae Haemophilus parainfluenzae MIC 4.0 ug.mL-1 10.1021/jm00403a025
Helicobacter pylori Helicobacter pylori MIC50 1.8 ug.mL-1 10.1016/s0960-894x(98)00726-4
Homo sapiens Acetylcholinesterase AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Aldehyde oxidase IC50 96900.0 nM None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump AC50 170000.4 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Caco-2 logPapp -5.49 None 10.1016/j.bmc.2011.03.011
Homo sapiens Caco-2 logPapp -5.43 None 10.1016/j.bmc.2009.08.022
Homo sapiens Caco-2 logPapp -5.15 None 10.1016/j.bmc.2011.03.011
Homo sapiens Caco-2 Papp 0.58 ucm/s 10.1016/j.bmc.2013.11.037
Homo sapiens Caco-2 Papp 9.89 ucm/s 10.1016/j.bmc.2013.11.037
Homo sapiens Caco-2 Papp nan None 10.1021/jm060055x
Homo sapiens Caco-2 Ratio 16.92 None 10.1016/j.bmc.2013.11.037
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity 89.0 % 10.1021/jm7015683
Homo sapiens Canalicular multispecific organic anion transporter 1 FC 1.0 None 10.1124/dmd.110.034629
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 7541.4 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 1B1 IC50 40000.0 nM 10.1016/j.ejmech.2017.04.042
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2B6 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C19 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C8 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Inhibition 10.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 2J2 IC50 50000.0 nM 10.1124/dmd.112.048264
Homo sapiens Cytochrome P450 3A4 Activity nan None None
Homo sapiens Cytochrome P450 3A4 IC50 190.0 nM 10.1021/jm801332q
Homo sapiens Cytochrome P450 3A4 IC50 1900.0 nM 10.1021/jm801332q
Homo sapiens Cytochrome P450 3A4 IC50 33000.0 nM 10.1021/jm021012t
Homo sapiens Cytochrome P450 3A4 IC50 132129.56 nM 10.1016/j.ejmech.2008.12.004
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Inhibition 45.0 % 10.1124/dmd.111.039180
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1124/dmd.111.038208
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Cytochrome P450 3A4 Kinact 0.055 min-1 10.2174/138920005774330639
Homo sapiens Cytochrome P450 3A4 Kinact 0.062 min-1 10.2174/138920005774330639
Homo sapiens Cytochrome P450 3A4 Kinact 0.097 min-1 10.2174/138920005774330639
Homo sapiens Cytochrome P450 3A4 Kinact 0.173 min-1 10.2174/138920005774330639
Homo sapiens Cytochrome P450 3A4 Log 1/Km -1.785 None 10.1016/j.bmcl.2005.06.015
Homo sapiens Cytochrome P450 3A4 mechanism based inhibition nan None 10.2174/138920005774330639
Homo sapiens Cytochrome P450 3A4 Ratio IC50 5.0 None 10.1021/tx300075j
Homo sapiens Cytochrome P450 51 IC50 200000.0 nM 10.1124/dmd.106.013888
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Geminin Potency 1636.0 nM None
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens HEK293 CC50 20000.0 nM 10.6019/CHEMBL4513161
Homo sapiens HeLa IC20 110.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens HeLa IC20 210.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens HeLa IC50 170.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens HeLa IC50 400.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 39.0 nM 10.1021/jm901107f
Homo sapiens HERG IC50 39000.0 nM 10.1016/j.bmcl.2004.06.070
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Inhibition 27.0 % 10.1016/j.bmc.2010.08.035
Homo sapiens HERG Inhibition 27.0 % 10.1021/jm901107f
Homo sapiens HERG Inhibition 50.0 % 10.1016/j.bmcl.2010.08.030
Homo sapiens HERG Inhibition 90.0 % 10.1016/j.bmc.2010.08.035
Homo sapiens HERG Inhibition 90.0 % 10.1021/jm901107f
Homo sapiens HERG Ki nan None None
Homo sapiens HFF CC50 475000.0 nM 10.1021/jm101593u
Homo sapiens Histamine H1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -64.69 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -10.35 % 10.6019/CHEMBL4808148
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens AUC 4010.0 ng.hr.mL-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens AUC 4021.4 ng.hr.mL-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens AUC 4787.4 ng.hr.mL-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens AUC 4852.6 ng.hr.mL-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens AUC 7700.0 ng.hr.mL-1 10.1128/aac.01270-08
Homo sapiens Homo sapiens CL 1.147 mL.min-1.kg-1 10.1124/dmd.112.049312
Homo sapiens Homo sapiens CL 5.3 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 5.6 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 5.6 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 7.169 mL.min-1.kg-1 10.1124/dmd.112.049312
Homo sapiens Homo sapiens CL 23.33 mL.min-1.kg-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens CL 225.0 mL.min-1.kg-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens CL_renal 0.3 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL_renal 0.34 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens Cmax 1519.2 nM 10.4172/jbb.1000041
Homo sapiens Homo sapiens Cmax 1592.77 nM 10.4172/jbb.1000041
Homo sapiens Homo sapiens Cmax 2725.02 nM 10.1128/aac.01270-08
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 5.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 35.0 % 10.1016/j.bmc.2007.08.060
Homo sapiens Homo sapiens Fa 0.5 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fabs 35.0 % 10.1124/dmd.110.034629
Homo sapiens Homo sapiens F_fraction 0.35 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.91 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.77 None 10.1021/jm901371v
Homo sapiens Homo sapiens K 0.415 /hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens K 1.23 /hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens K 1.34 /hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens K 2.26 /hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens Kel 0.443 /hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens Kel 0.825 /hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens Ratio 1.07 None 10.4172/jbb.1000041
Homo sapiens Homo sapiens Ratio AUC 1.03 None 10.4172/jbb.1000041
Homo sapiens Homo sapiens Ratio AUC 1.04 None 10.4172/jbb.1000041
Homo sapiens Homo sapiens T1/2 2.0 hr 10.1021/acs.jmedchem.5b00201
Homo sapiens Homo sapiens T1/2 2.0 hr 10.1128/aac.01270-08
Homo sapiens Homo sapiens T1/2 3.61 hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens T1/2 3.64 hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens Tmax 1.38 hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens Tmax 1.4 hr 10.4172/jbb.1000041
Homo sapiens Homo sapiens Vd 0.95 L.kg-1 10.1021/acs.jmedchem.5b00201
Homo sapiens Homo sapiens Vd 8.8 L.kg-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens Vd 10.4 L.kg-1 10.4172/jbb.1000041
Homo sapiens Homo sapiens Vdss 0.95 L.kg-1 10.1021/jm901371v
Homo sapiens HSP60/HSP10 IC50 100000.0 nM 10.1016/j.bmcl.2019.02.028
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens Liver microsome CLH nan None 10.1124/dmd.111.039180
Homo sapiens Liver microsome Drug metabolism nan None 10.1124/dmd.111.039180
Homo sapiens Liver microsome PB 57.1 pmol 10.1124/dmd.111.039180
Homo sapiens Liver microsomes Activity 135.0 pmol 10.1021/tx300075j
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens Low molecular weight phosphotyrosine protein phosphatase IC50 47100.0 nM None
Homo sapiens Low molecular weight phosphotyrosine protein phosphatase IC50 80000.0 nM None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens MG-63 Activity 60.0 % 10.1128/aac.00729-05
Homo sapiens MG-63 IC20 130.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC20 180.0 ug ml-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC50 300.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens MG-63 IC50 310.0 ug.mL-1 10.1128/aac.00729-05
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Motilin receptor AC50 23999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Motilin receptor EC50 50.12 nM 10.1016/j.bmcl.2008.10.072
Homo sapiens Motilin receptor EC50 50.12 nM 10.1021/jm801332q
Homo sapiens Motilin receptor EC50 400.0 nM 10.1021/jm0304865
Homo sapiens Motilin receptor EC50 630.96 nM 10.1016/j.bmcl.2008.10.072
Homo sapiens Motilin receptor EC50 1000.0 nM 10.1016/j.bmc.2010.08.035
Homo sapiens Motilin receptor EC50 1000.0 nM 10.1016/j.bmcl.2011.04.078
Homo sapiens Motilin receptor IC50 43.65 nM 10.1016/0960-894X(95)00122-A
Homo sapiens Motilin receptor IC50 70.79 nM 10.1016/0960-894X(95)00122-A
Homo sapiens Motilin receptor Intrinsic activity 1.3 None 10.1021/jm801332q
Homo sapiens Motilin receptor Ki 37000.0 nM 10.1021/jm0304865
Homo sapiens Multidrug and toxin extrusion protein 1 IC50 500000.0 nM 10.1021/jm301302s
Homo sapiens Multidrug and toxin extrusion protein 1 Inhibition 7.0 % 10.1021/jm301302s
Homo sapiens Multidrug resistance-associated protein 1 Activity 0.16 None 10.1128/aac.44.6.1697-1700.2000
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens PBMC Inhibition -32.0 % 10.1016/j.bmcl.2006.08.130
Homo sapiens PBMC Inhibition 22.0 % 10.1016/j.bmcl.2006.08.130
Homo sapiens PBMC Inhibition nan % 10.1016/j.bmcl.2006.08.130
Homo sapiens Peroxisome proliferator-activated receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens P-glycoprotein 1 Activity 1.0 % 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Activity 4.0 nM/mg*min 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/j.ejphar.2003.11.035
Homo sapiens P-glycoprotein 1 Activity nan None 10.1016/s0014-2999(98)00607-4
Homo sapiens P-glycoprotein 1 Activity nan None 10.1124/dmd.104.000521
Homo sapiens P-glycoprotein 1 Activity nan None None
Homo sapiens P-glycoprotein 1 IC50 43000.0 nM 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 IC50 50000.0 nM 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Inhibition 1.0 % 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Inhibition 101.0 % 10.1023/a:1018877803319
Homo sapiens P-glycoprotein 1 Ki 37790.0 nM 10.1124/mol.61.5.964
Homo sapiens P-glycoprotein 1 Ki 1000000.0 nM 10.1124/mol.61.5.964
Homo sapiens P-glycoprotein 1 % maximum response 4.35 % None
Homo sapiens P-glycoprotein 1 Papp 0.94 nm/s None
Homo sapiens P-glycoprotein 1 Papp 13.5 nm/s None
Homo sapiens P-glycoprotein 1 Ratio_ATPase activity 2.27 None None
Homo sapiens P-glycoprotein 1 Ratio_Papp 14.4 None None
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Proteinase-activated receptor 2 Inhibition nan % 10.1128/aac.00140-07
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Rap guanine nucleotide exchange factor 3 Potency 100000.0 nM None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine-protein kinase PLK1 Potency 21192.3 nM None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 3176.2 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Serum albumin Kd 12000.0 nM 10.1128/aac.00971-08
Homo sapiens Serum albumin Ratio 0.5 None 10.1128/aac.00971-08
Homo sapiens Serum amyloid P-component Binding 73.0 % 10.1021/jm00107a036
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Sodium channel protein type V alpha subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Sodium channel protein type V alpha subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Solute carrier family 22 member 1 Inhibition 14.0 % 10.1021/jm8003152
Homo sapiens Solute carrier family 22 member 7 Activity nan None 10.1124/dmd.104.003301
Homo sapiens Solute carrier organic anion transporter family member 1A2 Activity 66.0 % None
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 58.8 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 75.85 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 45.8 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 92.42 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 2B1 Inhibition -19.0 % 10.1021/jm300212s
Homo sapiens Sphingomyelin phosphodiesterase Potency 70794.6 nM None
Homo sapiens Thiosulfate sulfurtransferase IC50 100000.0 nM 10.1016/j.bmcl.2019.02.028
Homo sapiens Thrombin AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 3662.6 nM None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Klebsiella aerogenes Klebsiella aerogenes MIC 32.0 ug.mL-1 10.1128/aac.00710-10
Klebsiella aerogenes Klebsiella aerogenes MIC 128.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Klebsiella aerogenes Klebsiella aerogenes MIC 1024.0 ug.mL-1 10.1128/aac.00710-10
Klebsiella aerogenes Klebsiella aerogenes MIC 110000.0 nM 10.1016/j.bmc.2012.12.030
Klebsiella aerogenes Klebsiella aerogenes MIC 350000.0 nM 10.1016/j.bmc.2012.12.030
Klebsiella pneumoniae Klebsiella pneumoniae Activity 50.0 uM 10.1016/j.bmc.2019.04.004
Klebsiella pneumoniae Klebsiella pneumoniae Activity nan None 10.1021/np800142n
Klebsiella pneumoniae Klebsiella pneumoniae Activity nan None 10.1128/aac.00710-10
Klebsiella pneumoniae Klebsiella pneumoniae IZ 10.0 mm 10.1016/j.ejmech.2019.04.002
Klebsiella pneumoniae Klebsiella pneumoniae IZ 10.0 mm 10.1016/j.ejmech.2019.111744
Klebsiella pneumoniae Klebsiella pneumoniae IZ 14.0 mm 10.1016/j.ejmech.2014.05.084
Klebsiella pneumoniae Klebsiella pneumoniae IZ nan None 10.1021/acs.jnatprod.8b00200
Klebsiella pneumoniae Klebsiella pneumoniae MBC 64.0 ug ml-1 10.1016/j.ejmech.2019.04.063
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.143 ug.mL-1 10.1128/aac.00405-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b01780
Klebsiella pneumoniae Klebsiella pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.00405-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Klebsiella pneumoniae Klebsiella pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00405-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00405-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1021/jm00394a001
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.3 ug.mL-1 10.1021/jm00215a025
Klebsiella pneumoniae Klebsiella pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 24.0 ug.mL-1 10.1128/aac.00405-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.bmc.2016.06.044
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/S0960-894X(00)80333-9
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)80238-9
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Klebsiella pneumoniae Klebsiella pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00715-09
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.04.063
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Klebsiella pneumoniae Klebsiella pneumoniae MIC 200.0 ug.mL-1 10.1021/acs.jnatprod.0c01212
Klebsiella pneumoniae Klebsiella pneumoniae MIC 256.0 ug.mL-1 10.1021/np4006794
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6300.0 nM 10.1016/0960-894X(95)00122-A
Klebsiella pneumoniae Klebsiella pneumoniae MIC 16000.0 nM 10.1016/j.bmc.2019.03.034
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20000.0 nM 10.6019/CHEMBL4513161
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64000.0 nM 10.1016/j.bmc.2019.03.034
Klebsiella pneumoniae Klebsiella pneumoniae MIC 200000.0 nM 10.1016/j.bmc.2019.04.004
Klebsiella pneumoniae Klebsiella pneumoniae MIC 200000.0 nM 10.1016/j.ejmech.2019.111708
Klebsiella pneumoniae Klebsiella pneumoniae MIC nan None 10.1016/j.ejmech.2018.06.023
Klebsiella pneumoniae Klebsiella pneumoniae Ratio 24.0 None 10.1128/aac.00405-08
Kocuria rhizophila Kocuria rhizophila IZ nan None 10.1021/acs.jnatprod.8b00200
Lactococcus lactis Lactococcus lactis MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Lactococcus lactis Lactococcus lactis MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Lactococcus lactis Lactococcus lactis MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Legionella pneumophila Legionella pneumophila MIC 0.06 ug.mL-1 10.1128/aac.01383-07
Legionella pneumophila Legionella pneumophila MIC 0.25 ug.mL-1 10.1128/aac.01383-07
Legionella pneumophila Legionella pneumophila MIC 0.5 ug.mL-1 10.1128/aac.01383-07
Listeria monocytogenes Listeria monocytogenes MIC 256.0 ug.mL-1 10.1128/aac.01557-09
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 0.0 % 10.1128/aac.00426-10
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 15.0 % 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 23.0 % 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 23.1 % 10.1128/aac.00426-10
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 27.0 % 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 33.3 % 10.1128/aac.00426-10
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 50.0 % 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri Activity 74.0 % 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MBC 1.0 ug ml-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MBC50 2.0 ug ml-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MBC50 32.0 ug ml-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MBC90 128.0 ug ml-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC 0.5 ug.mL-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC50 0.5 ug.mL-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC50 16.0 ug.mL-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC90 16.0 ug.mL-1 10.1128/aac.00624-09
Mammaliicoccus sciuri Mammaliicoccus sciuri MIC90 32.0 ug.mL-1 10.1128/aac.00624-09
Metamycoplasma hominis Metamycoplasma hominis MIC 0.008 ug.mL-1 10.1128/aac.00849-08
Metamycoplasma hominis Metamycoplasma hominis MIC 16.0 ug.mL-1 10.1128/aac.01383-07
Metamycoplasma hominis Metamycoplasma hominis MIC 32.0 ug.mL-1 10.1128/aac.01383-07
Metamycoplasma hominis Metamycoplasma hominis MIC 256.0 ug.mL-1 10.1128/aac.01383-07
Metamycoplasma hominis Metamycoplasma hominis MIC50 0.016 ug.mL-1 10.1128/aac.00849-08
Metamycoplasma hominis Metamycoplasma hominis MIC90 0.032 ug.mL-1 10.1128/aac.00849-08
Micrococcus Micrococcus MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Micrococcus Micrococcus MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Micrococcus Micrococcus MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Micrococcus luteus Micrococcus luteus IC50 0.24 ug.mL-1 10.1016/j.bmcl.2014.04.084
Micrococcus luteus Micrococcus luteus IC50 310.0 nM 10.1016/j.bmcl.2015.05.041
Micrococcus luteus Micrococcus luteus IZ 10.0 mm 10.1016/j.bmcl.2012.07.059
Micrococcus luteus Micrococcus luteus IZ 25.0 mm 10.1021/np2008279
Micrococcus luteus Micrococcus luteus IZ 30.0 mm 10.1016/j.ejmech.2014.05.084
Micrococcus luteus Micrococcus luteus IZ 32.0 mm 10.1016/j.ejmech.2016.06.051
Micrococcus luteus Micrococcus luteus IZ 44.0 mm 10.1016/j.ejmech.2016.06.051
Micrococcus luteus Micrococcus luteus MIC 0.02 ug.mL-1 10.1016/j.bmcl.2003.12.059
Micrococcus luteus Micrococcus luteus MIC 0.2 ug.mL-1 10.1021/np030131o
Micrococcus luteus Micrococcus luteus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2011.04.004
Micrococcus luteus Micrococcus luteus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Micrococcus luteus Micrococcus luteus MIC 1.0 ug.mL-1 10.1021/np300554f
Micrococcus luteus Micrococcus luteus MIC nan None 10.1021/np4006794
Moraxella catarrhalis Moraxella catarrhalis Activity 0.0 % 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis Activity 100.0 % 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.032 ug.mL-1 10.1021/jm8000136
Moraxella catarrhalis Moraxella catarrhalis MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.13 ug.mL-1 10.1016/j.bmcl.2008.07.118
Moraxella catarrhalis Moraxella catarrhalis MIC 0.13 ug.mL-1 10.1016/j.bmcl.2008.10.109
Moraxella catarrhalis Moraxella catarrhalis MIC 8.0 ug.mL-1 10.1016/j.bmcl.2011.10.101
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC50 0.25 ug.mL-1 10.1128/aac.01017-06
Moraxella catarrhalis Moraxella catarrhalis MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC90 0.25 ug.mL-1 10.1128/aac.01017-06
Morganella morganii Morganella morganii MIC 256.0 ug.mL-1 10.1021/np4006794
Mucor racemosus Mucor racemosus IZ nan None 10.1021/acs.jnatprod.8b00200
Mus musculus Mus musculus Concentration 0.7 ug ml-1 ml-1 10.1021/jm00403a025
Mus musculus Mus musculus Concentration 2.5 ug ml-1 ml-1 10.1021/jm00403a025
Mus musculus Mus musculus Concentration 2.7 ug ml-1 ml-1 10.1021/jm00403a025
Mus musculus Mus musculus Concentration 5.6 ug ml-1 ml-1 10.1021/jm00403a025
Mus musculus Mus musculus Concentration nan None 10.1021/jm00403a025
Mus musculus Mus musculus ED50 1.6 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 2.5 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 2.7 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 2.8 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 3.5 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 4.1 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 12.0 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 14.0 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 15.0 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 18.0 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 18.3 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus ED50 56.6 mg.kg-1 10.1021/jm020568d
Mus musculus Mus musculus ED50 57.0 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus ED50 71.0 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 100.0 mg.kg-1 10.1021/jm00173a028
Mus musculus Mus musculus ED50 100.0 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus ED50 111.0 mg.kg-1 10.1021/jm020568d
Mus musculus Mus musculus ED50 300.0 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus ED50 326.0 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus ED50 346.0 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus ED50 442.0 mg.kg-1 10.1021/jm980240d
Mus musculus Mus musculus Inhibition 42.0 % 10.1016/j.bmcl.2006.08.076
Mus musculus Mus musculus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2004.12.067
Mus musculus Mus musculus PD50 150.0 mg kg-1 10.1021/jm960436i
Mus musculus Mus musculus Plasma concentration 0.0 ug ml-1 10.1021/jm00173a028
Mus musculus Mus musculus Plasma concentration 0.01 ug ml-1 10.1021/jm00173a028
Mus musculus Mus musculus Plasma concentration 0.1 ug ml-1 10.1021/jm00173a028
Mus musculus Mus musculus Plasma concentration 4.26 ug ml-1 10.1021/jm00173a028
Mus musculus Mus musculus Plasma concentration 4.36 ug ml-1 10.1021/jm00173a028
Mus musculus Mus musculus Plasma concentration 5.84 ug ml-1 10.1021/jm00173a028
Mus musculus Mus musculus Plasma concentration 5.96 ug ml-1 10.1021/jm00173a028
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus P-glycoprotein 1 IC50 35000.0 nM 10.1021/jm021012t
Mus musculus P-glycoprotein 1 Ki 1000000.0 nM 10.1124/jpet.102.037549
Mus musculus P-glycoprotein 3 Activity nan None 10.1006/abbi.1997.0537
Mus musculus P-glycoprotein 3 Activity nan None 10.1046/j.1440-1681.2000.03308.x
Mus musculus P-glycoprotein 3 IC50 43000.0 nM 10.1021/jm021012t
Mus musculus P-glycoprotein 3 IC50 50000.0 nM 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ki 1000000.0 nM 10.1124/jpet.102.037549
Mus musculus P-glycoprotein 3 Ratio 2.8 None 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ratio 3.3 None 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ratio 3.9 None 10.1021/jm021012t
Mus musculus Plasma Ratio AUC 3.4 None 10.1124/dmd.110.034629
Mus musculus Solute carrier family 22 member 7 Activity nan None 10.1124/mol.62.1.7
Mycobacterium avium Mycobacterium avium MIC 128.0 ug.mL-1 10.1016/j.ejmech.2017.09.014
Mycobacterium avium Mycobacterium avium MIC 256.0 ug.mL-1 10.1016/j.ejmech.2017.09.014
Mycobacterium avium Mycobacterium avium MIC 512.0 ug.mL-1 10.1016/j.ejmech.2017.09.014
Mycobacterium tuberculosis Mycobacterium tuberculosis Activity nan None 10.1128/aac.00012-09
Mycobacterium tuberculosis variant bovis Mycobacterium tuberculosis variant bovis MIC 4.0 ug.mL-1 10.1128/aac.01302-08
Mycobacterium tuberculosis variant bovis Mycobacterium tuberculosis variant bovis MIC 16.0 ug.mL-1 10.1128/aac.01302-08
Mycobacterium tuberculosis variant bovis Mycobacterium tuberculosis variant bovis MIC 128.0 ug.mL-1 10.1128/aac.01302-08
Mycobacterium ulcerans Mycobacterium ulcerans Activity nan None 10.1128/aac.00400-10
Mycobacterium ulcerans Mycobacterium ulcerans MIC 0.5 ug.mL-1 10.1128/aac.00400-10
Mycobacterium ulcerans Mycobacterium ulcerans MIC 1.0 ug.mL-1 10.1128/aac.00400-10
Mycobacterium ulcerans Mycobacterium ulcerans MIC 16.0 ug.mL-1 10.1128/aac.00400-10
Mycobacteroides abscessus Mycobacteroides abscessus MIC50 1.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides abscessus Mycobacteroides abscessus MIC90 16.0 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides chelonae Mycobacteroides chelonae MIC 0.25 ug.mL-1 10.1128/aac.00590-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC 1.0 ug.mL-1 10.1128/aac.00590-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC 20.0 ug.mL-1 10.1128/aac.00590-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC 500.0 ug.mL-1 10.1128/aac.00590-09
Mycobacteroides chelonae Mycobacteroides chelonae MIC50 0.5 ug.mL-1 10.1128/aac.00695-08
Mycobacteroides chelonae Mycobacteroides chelonae MIC90 32.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC50 64.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium fortuitum Mycolicibacterium fortuitum MIC90 64.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium mageritense Mycolicibacterium mageritense MIC 32.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium peregrinum Mycolicibacterium peregrinum MIC50 1.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium peregrinum Mycolicibacterium peregrinum MIC90 16.0 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis Activity nan None 10.1016/j.ejmech.2019.05.081
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ nan None 10.1021/acs.jnatprod.8b00200
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 0.12 ug.mL-1 10.1128/aac.00695-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 2.5 ug.mL-1 10.1128/aac.00298-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 3.0 ug.mL-1 10.1128/aac.00012-09
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 4.0 ug.mL-1 10.1128/aac.00012-09
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 4.0 ug.mL-1 10.1128/aac.01275-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 10.0 ug.mL-1 10.1128/aac.00298-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 12.0 ug.mL-1 10.1128/aac.00012-09
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 32.0 ug.mL-1 10.1128/aac.00012-09
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 32.0 ug.mL-1 10.1128/aac.01275-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis MIC 128.0 ug.mL-1 10.1128/aac.01275-08
Mycolicibacterium smegmatis Mycolicibacterium smegmatis Ratio 4.0 None 10.1128/aac.00298-08
Mycoplasma putrefaciens Mycoplasma putrefaciens MIC 0.03 ug.mL-1 10.1128/aac.00420-07
Mycoplasma putrefaciens Mycoplasma putrefaciens MIC50 0.03 ug.mL-1 10.1128/aac.00420-07
Mycoplasma putrefaciens Mycoplasma putrefaciens MIC90 0.03 ug.mL-1 10.1128/aac.00420-07
Mycoplasma putrefaciens Mycoplasma putrefaciens MIC90 0.125 ug.mL-1 10.1128/aac.00420-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae Activity nan None 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.001 ug.mL-1 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.00195 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.004 ug.mL-1 10.1128/aac.01383-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.007 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.01 ug.mL-1 10.1128/aac.01563-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01383-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 0.063 ug.mL-1 10.1128/aac.00582-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01383-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.00582-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 0.004 ug.mL-1 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 0.0078 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 128.0 ug.mL-1 10.1128/aac.01563-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC50 128.0 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 0.004 ug.mL-1 10.1128/aac.00849-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 0.0156 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00779-07
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 128.0 ug.mL-1 10.1128/aac.01684-08
Mycoplasmoides pneumoniae Mycoplasmoides pneumoniae MIC90 512.0 ug.mL-1 10.1128/aac.01563-08
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 22.8 % 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 77.2 % 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity nan None 10.1128/aac.00309-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.0 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 3.0 ug.mL-1 10.1128/aac.00309-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 4.0 ug.mL-1 10.1128/aac.00309-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC50 1.0 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC90 2.0 ug.mL-1 10.1128/aac.00788-10
Neisseria meningitidis Neisseria meningitidis Activity 0.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis Activity 26.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis Activity 74.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC 0.03 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC 0.032 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC50 0.12 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC50 0.75 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC90 0.25 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC90 1.0 ug.mL-1 10.1128/aac.00994-08
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Oryctolagus cuniculus Motilin receptor Activity 97.0 % 10.1016/j.bmcl.2010.08.030
Oryctolagus cuniculus Motilin receptor Activity 97.0 % 10.1021/jm901107f
Oryctolagus cuniculus Motilin receptor EC50 1200.0 nM 10.1016/j.bmcl.2010.08.030
Oryctolagus cuniculus Motilin receptor EC50 1200.0 nM 10.1016/j.bmcl.2011.04.078
Oryctolagus cuniculus Motilin receptor EC50 1200.0 nM 10.1021/jm901107f
Oryctolagus cuniculus Oryctolagus cuniculus EC50 316.23 nM 10.1016/0960-894X(95)00122-A
Oryctolagus cuniculus Oryctolagus cuniculus pED50 5.85 None 10.1016/s0960-894x(98)00111-5
Oryctolagus cuniculus Oryctolagus cuniculus pED50 5.85 None 10.1021/jm00010a024
Oryctolagus cuniculus Stomach Activity 14.0 % 10.1021/jm801332q
Oryctolagus cuniculus Stomach Activity 69.0 % 10.1021/jm801332q
Oryctolagus cuniculus Stomach Activity 189.0 % 10.1021/jm801332q
Oryctolagus cuniculus Stomach Activity 490.0 % 10.1016/j.bmcl.2008.10.071
Oryctolagus cuniculus Stomach Activity 490.0 % 10.1021/jm801332q
Oryctolagus cuniculus Stomach Emax 69.0 % 10.1016/j.bmcl.2008.10.072
Oryctolagus cuniculus Stomach Emax 189.0 % 10.1016/j.bmcl.2008.10.072
Oryctolagus cuniculus Stomach Emax 368.0 % 10.1016/j.bmcl.2008.10.072
Oryctolagus cuniculus Stomach Emax 490.0 % 10.1016/j.bmcl.2008.10.072
Pasteurella multocida Pasteurella multocida Activity 4.5 % 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida Activity 77.3 % 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC 0.25 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC 0.47 ug.mL-1 10.1128/aac.00245-08
Pasteurella multocida Pasteurella multocida MIC 0.78 ug.mL-1 10.1021/jm960436i
Pasteurella multocida Pasteurella multocida MIC 1.88 ug.mL-1 10.1128/aac.00245-08
Pasteurella multocida Pasteurella multocida MIC 3.8 ug.mL-1 10.1128/aac.00245-08
Pasteurella multocida Pasteurella multocida MIC50 2.0 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC90 4.0 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida Ratio 2.0 None 10.1128/aac.00245-08
Pasteurella multocida Pasteurella multocida Ratio 8.0 None 10.1128/aac.00245-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 8.0 ug.mL-1 10.1021/jm00403a025
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 1.0 ug.mL-1 10.1021/jm00403a025
Phocaeicola vulgatus Phocaeicola vulgatus MIC 0.5 ug.mL-1 10.1021/jm00403a025
Plasmodium falciparum Plasmodium falciparum IC50 9400.0 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 18000.0 nM 10.1016/j.bmc.2010.01.068
Plasmodium falciparum Plasmodium falciparum IC50 20300.0 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 34700.0 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 39500.0 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 68000.0 nM 10.1021/acs.jmedchem.5b01485
Plasmodium falciparum Plasmodium falciparum Potency 9285.0 nM None
Prescottella equi Prescottella equi MBC50 32.0 mg/L 10.1128/aac.00344-06
Prescottella equi Prescottella equi MBC90 64.0 mg/L 10.1128/aac.00344-06
Prescottella equi Prescottella equi MIC50 0.5 ug.mL-1 10.1128/aac.00344-06
Prescottella equi Prescottella equi MIC90 2.0 ug.mL-1 10.1128/aac.00344-06
Prevotella melaninogenica Prevotella melaninogenica MIC 1.0 ug.mL-1 10.1021/jm00403a025
Prevotella melaninogenica Prevotella melaninogenica MIC 2.0 ug.mL-1 10.1021/jm00403a025
Proteus mirabilis Proteus mirabilis MIC 64.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Proteus vulgaris Proteus vulgaris IZ 6.0 mm 10.1016/j.ejmech.2019.04.002
Proteus vulgaris Proteus vulgaris IZ 20.0 mm 10.1016/j.ejmech.2014.05.084
Proteus vulgaris Proteus vulgaris IZ 25.1 mm 10.1007/s00044-013-0755-5
Proteus vulgaris Proteus vulgaris IZ nan None 10.1021/acs.jnatprod.8b00200
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity 200.0 uM 10.1016/j.bmc.2019.04.004
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1016/j.bmcl.2014.12.010
Pseudomonas aeruginosa Pseudomonas aeruginosa Activity nan None 10.1021/np800142n
Pseudomonas aeruginosa Pseudomonas aeruginosa FICI 1.0 None 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa GI 67.6 % 10.1016/j.bmcl.2014.12.010
Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 0.26 ug.mL-1 10.1016/j.bmcl.2014.04.084
Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 33.2 ug.mL-1 10.1016/j.bmcl.2014.12.010
Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition 45.7 % 10.1016/j.bmcl.2014.12.010
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 10.0 mm 10.1016/j.bmcl.2012.07.059
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 16.0 mm 10.1016/j.ejmech.2010.04.020
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 18.0 mm 10.1016/j.ejmech.2019.04.002
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 21.0 mm 10.1016/j.ejmech.2014.05.084
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 30.0 mm 10.1016/j.ejmech.2016.06.051
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ nan None 10.1007/s00044-009-9177-9
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ nan None 10.1021/acs.jnatprod.8b00200
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 64.0 ug ml-1 10.1016/j.ejmech.2019.04.063
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.125 ug.mL-1 10.1007/s00044-011-9951-3
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2.0 ug.mL-1 10.1128/aac.00801-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1016/j.bmc.2019.06.010
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1016/j.bmc.2020.115729
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1016/j.bmcl.2015.07.010
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 32.0 ug.mL-1 10.1021/acs.jnatprod.0c01212
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 62.5 ug.mL-1 10.1021/acs.jnatprod.0c01309
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 63.0 nM 10.1016/j.bmcl.2023.129301
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.04.063
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.111850
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/acs.jmedchem.6b01780
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1039/d2md00041e
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 140.0 ug.mL-1 10.1128/aac.01071-07
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1021/np4006794
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1128/aac.00710-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 512.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1024.0 ug.mL-1 10.1021/acs.jmedchem.6b01742
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1024.0 ug.mL-1 10.1128/aac.00710-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2000.0 nM 10.1016/j.bmcl.2023.129301
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4000.0 nM 10.1016/j.bmc.2019.03.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 8000.0 nM 10.1016/j.bmcl.2023.129301
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 20000.0 nM 10.6019/CHEMBL4513161
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64000.0 nM 10.1016/j.bmc.2019.03.034
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128000.0 nM 10.1016/j.bmcl.2023.129301
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128000.0 nM 10.1021/acs.jmedchem.9b00288
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200000.0 nM 10.1016/j.bmc.2016.04.058
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200000.0 nM 10.1016/j.bmc.2019.04.004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 200000.0 nM 10.1016/j.ejmech.2019.111708
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1016/j.ejmech.2018.06.023
Pseudomonas aeruginosa Pseudomonas aeruginosa Survival 93.5 % 10.1016/j.ejmech.2008.12.014
Pseudomonas sp. Pseudomonas sp. MIC 20.0 ug.mL-1 10.1128/aac.00802-06
Pseudomonas sp. Pseudomonas sp. MIC 2500.0 ug.mL-1 10.1128/aac.00802-06
Raoultella planticola Raoultella planticola IC50 0.19 ug.mL-1 10.1016/j.bmcl.2013.10.010
Raoultella planticola Raoultella planticola IC50 0.21 ug.mL-1 10.1016/j.bmcl.2014.04.084
Raoultella planticola Raoultella planticola IC50 350.0 nM 10.1016/j.bmcl.2015.05.041
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Cyclooxygenase-1 AC50 3800.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Plasma Fu 0.1 None 10.1021/jm901371v
Rattus norvegicus Rattus norvegicus Activity 0.0 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.01 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.03 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.04 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.15 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.17 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.35 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 0.4 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 1.0 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 2.5 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 7.5 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 8.8 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Activity 10.8 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus ALB 37000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 311.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 366.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 390.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 454.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 45.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 49.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 65.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 67.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 81.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 86.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 107.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 93.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 136.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 146.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 104.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 390.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 1063.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 1076.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 238.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 315.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 328.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 532.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CL 17.4 mL.min-1.kg-1 10.1124/dmd.112.049312
Rattus norvegicus Rattus norvegicus CL 22.38 mL.min-1.kg-1 10.1124/dmd.112.049312
Rattus norvegicus Rattus norvegicus CO2 25670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 28330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 29000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 34000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Concentration 0.1 ug ml-1 ml-1 10.1021/jm00403a025
Rattus norvegicus Rattus norvegicus Concentration 0.2 ug ml-1 ml-1 10.1021/jm00403a025
Rattus norvegicus Rattus norvegicus Concentration 0.4 ug ml-1 ml-1 10.1021/jm00403a025
Rattus norvegicus Rattus norvegicus CREAT 1.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 38.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1303.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1376.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1540.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 31.9 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 34.13 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 39.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 42.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 124000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 135300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 159000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 164300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 131.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 152.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 199.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 259.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 7.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13393.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 14587.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 15179.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 15941.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 84.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 89.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 96.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.4 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.9 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.97 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.47 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 384300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 388700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 396700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 401300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.83 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.7 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.9 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 65.47 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 52.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 91.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 389.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 796.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 4.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 3.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 11.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 520.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1229.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1297.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1949.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 99.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 108.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 120.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 123.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Plasma concentration 0.0 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.01 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.02 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.03 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.04 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.11 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.48 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 0.7 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 1.06 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 1.16 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 1.21 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 1.31 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus Plasma concentration 4.2 ug ml-1 10.1021/jm00173a028
Rattus norvegicus Rattus norvegicus PLAT 1070000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1119670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1227330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1382330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.66 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.72 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.83 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 9.14 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 4880000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5450000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6530000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6590000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 1.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 141.8 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.43 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.9 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.47 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 12.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 15.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 15.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 21.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13970.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 17330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 17670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Saccharomyces cerevisiae Saccharomyces cerevisiae IZ nan None 10.1021/acs.jnatprod.8b00200
Salmonella enterica Salmonella enterica IZ 8.0 mm 10.1016/j.bmcl.2012.07.059
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 8.0 mm 10.1016/j.ejmech.2014.05.084
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.5 ug.mL-1 10.1016/j.ejmech.2012.11.028
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 2.0 ug.mL-1 10.1016/j.ejmech.2012.11.028
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 2.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 4.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 64.0 ug.mL-1 10.1128/aac.01472-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 64.0 ug.mL-1 10.1128/aac.01678-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 128.0 ug.mL-1 10.1128/aac.00079-09
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 32000.0 nM 10.1021/acs.jmedchem.9b00288
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 55000.0 nM 10.1016/j.bmc.2012.12.030
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 350000.0 nM 10.1016/j.bmc.2012.12.030
Serratia marcescens Chitinase B IC50 300000.0 nM 10.1021/acs.jmedchem.5b00175
Serratia marcescens Serratia marcescens MIC 128.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 3.28 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 21.16 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.04359 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -5.62 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.22 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.0 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.0005254 None 10.1101/2020.04.03.023846
Staphylococcus Staphylococcus Activity 24.1 % 10.1128/aac.01453-08
Staphylococcus Staphylococcus Activity 33.6 % 10.1128/aac.01453-08
Staphylococcus Staphylococcus Activity 66.0 % 10.1128/aac.01453-08
Staphylococcus Staphylococcus Activity 75.4 % 10.1128/aac.01453-08
Staphylococcus Staphylococcus MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus Staphylococcus MIC 0.06 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC 0.12 ug.mL-1 10.1128/aac.00100-07
Staphylococcus Staphylococcus MIC 0.25 ug.mL-1 10.1128/aac.01453-08
Staphylococcus Staphylococcus MIC50 0.25 ug.mL-1 10.1128/aac.00100-07
Staphylococcus Staphylococcus MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus Staphylococcus MIC50 0.25 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC50 0.25 ug.mL-1 10.1128/aac.01453-08
Staphylococcus Staphylococcus MIC50 2.0 ug.mL-1 10.1128/aac.01453-08
Staphylococcus Staphylococcus MIC50 16.0 ug.mL-1 10.1128/aac.00100-07
Staphylococcus Staphylococcus MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus Staphylococcus MIC90 2.0 ug.mL-1 10.1128/aac.01453-08
Staphylococcus Staphylococcus MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus Staphylococcus MIC90 16.0 ug.mL-1 10.1128/aac.00100-07
Staphylococcus Staphylococcus MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 0.0 % 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus Activity 1.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 1.3 % 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus Activity 2.0 % 10.1128/aac.01398-07
Staphylococcus aureus Staphylococcus aureus Activity 4.0 % 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus Activity 4.5 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 5.0 % 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus Activity 8.4 % 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus Activity 10.9 % 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus Activity 11.0 % 10.1128/aac.01583-07
Staphylococcus aureus Staphylococcus aureus Activity 12.0 % 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus Activity 13.9 % 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus Activity 14.2 % 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus Activity 14.6 % 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus Activity 16.3 % 10.1128/aac.00090-10
Staphylococcus aureus Staphylococcus aureus Activity 18.4 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 20.7 % 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus Activity 21.1 % 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus Activity 23.0 % 10.1128/aac.01583-07
Staphylococcus aureus Staphylococcus aureus Activity 25.2 % 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus Activity 27.0 % 10.1128/aac.01583-07
Staphylococcus aureus Staphylococcus aureus Activity 32.5 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 32.6 % 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus Activity 33.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 35.0 % 10.1128/aac.01583-07
Staphylococcus aureus Staphylococcus aureus Activity 35.9 % 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus Activity 39.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 40.0 % 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus Activity 49.3 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 49.8 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 50.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 56.0 % 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus Activity 57.9 % 10.1128/aac.01244-06
Staphylococcus aureus Staphylococcus aureus Activity 60.7 % 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus Activity 65.2 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 65.3 % 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus Activity 67.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 73.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 74.3 % 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus Activity 74.5 % 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus Activity 77.9 % 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus Activity 78.7 % 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus Activity 81.3 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 84.3 % 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus Activity 85.0 % 10.1128/aac.00351-10
Staphylococcus aureus Staphylococcus aureus Activity 85.6 % 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus Activity 86.0 % 10.1128/aac.00846-07
Staphylococcus aureus Staphylococcus aureus Activity 87.5 % 10.1128/aac.00090-10
Staphylococcus aureus Staphylococcus aureus Activity 88.0 % 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus Activity 88.8 % 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus Activity 89.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 90.5 % 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus Activity 93.8 % 10.1128/aac.01244-06
Staphylococcus aureus Staphylococcus aureus Activity 94.0 % 10.1128/aac.00846-07
Staphylococcus aureus Staphylococcus aureus Activity 94.4 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 95.0 % 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus Activity 98.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 98.0 % 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.00470-10
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmc.2017.11.018
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmcl.2006.08.076
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmcl.2015.05.041
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.ejmech.2022.114333
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/acs.jmedchem.1c01905
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/jm0703183
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.00064-10
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.00804-08
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.00940-09
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.01395-07
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.01662-09
Staphylococcus aureus Staphylococcus aureus Antibiotic resistance nan None 10.1016/s0960-894x(98)00536-8
Staphylococcus aureus Staphylococcus aureus Bacterial counts 3.7 None 10.1021/jm025502x
Staphylococcus aureus Staphylococcus aureus DIZ nan None 10.1016/j.bmcl.2012.05.112
Staphylococcus aureus Staphylococcus aureus ED50 2.55 mg.kg-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus ED50 41.0 mg.kg-1 10.1021/jm00173a028
Staphylococcus aureus Staphylococcus aureus ED50 56.6 mg.kg-1 10.1021/jm015566s
Staphylococcus aureus Staphylococcus aureus ED50 100.0 mg.kg-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus FC 0.8 None 10.1128/aac.00273-08
Staphylococcus aureus Staphylococcus aureus FC 0.93 None 10.1128/aac.00273-08
Staphylococcus aureus Staphylococcus aureus FC 1.04 None 10.1128/aac.00273-08
Staphylococcus aureus Staphylococcus aureus FC 1.12 None 10.1128/aac.00273-08
Staphylococcus aureus Staphylococcus aureus FC 1.15 None 10.1128/aac.00273-08
Staphylococcus aureus Staphylococcus aureus FC 100.0 None 10.1038/nchembio820
Staphylococcus aureus Staphylococcus aureus FC 10000.0 None 10.1038/nchembio820
Staphylococcus aureus Staphylococcus aureus GI nan None 10.1016/j.bmc.2015.04.069
Staphylococcus aureus Staphylococcus aureus IC50 0.21 ug.mL-1 10.1016/j.bmcl.2013.10.010
Staphylococcus aureus Staphylococcus aureus IC50 0.23 ug.mL-1 10.1016/j.bmcl.2015.03.034
Staphylococcus aureus Staphylococcus aureus IC50 0.25 ug.mL-1 10.1016/j.bmcl.2013.10.010
Staphylococcus aureus Staphylococcus aureus IC50 0.32 ug.mL-1 10.1016/j.bmcl.2014.04.084
Staphylococcus aureus Staphylococcus aureus IC50 250.0 nM 10.1016/j.bmcl.2015.05.041
Staphylococcus aureus Staphylococcus aureus IZ 8.0 mm 10.1021/np200120d
Staphylococcus aureus Staphylococcus aureus IZ 8.0 mm 10.1021/np800142n
Staphylococcus aureus Staphylococcus aureus IZ 10.0 mm 10.1016/j.ejmech.2019.111744
Staphylococcus aureus Staphylococcus aureus IZ 19.0 mm 10.1016/j.ejmech.2010.04.020
Staphylococcus aureus Staphylococcus aureus IZ 23.0 mm 10.1016/j.ejmech.2014.05.084
Staphylococcus aureus Staphylococcus aureus IZ 24.0 mm 10.1016/j.ejmech.2019.04.002
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1016/j.bmcl.2012.05.112
Staphylococcus aureus Staphylococcus aureus IZ nan None 10.1021/acs.jnatprod.8b00200
Staphylococcus aureus Staphylococcus aureus log10cfu -0.17 None 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus log10cfu 0.27 None 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus MBC 1.0 ug ml-1 10.1016/j.ejmech.2011.12.039
Staphylococcus aureus Staphylococcus aureus MBC 1.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MBC 32.0 ug ml-1 10.1016/j.bmcl.2013.06.048
Staphylococcus aureus Staphylococcus aureus MBC 32.0 ug ml-1 10.1021/jm3012728
Staphylococcus aureus Staphylococcus aureus MBC 32.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MBC 64.0 ug ml-1 10.1016/j.ejmech.2011.12.039
Staphylococcus aureus Staphylococcus aureus MBC50 4.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MBC50 16.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC50 32.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC50 128.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MBC90 64.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC90 128.0 mg/L 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MBC90 128.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MBC90 256.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2004.06.045
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.bmcl.2006.09.036
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.ejmech.2011.08.001
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.ejmech.2012.11.028
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.ejmech.2015.09.020
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus MIC 0.063 ug.mL-1 10.1016/j.ejmech.2010.09.060
Staphylococcus aureus Staphylococcus aureus MIC 0.063 ug.mL-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus MIC 0.098 ug.mL-1 10.1016/j.bmcl.2005.11.061
Staphylococcus aureus Staphylococcus aureus MIC 0.1 ug.mL-1 10.1016/j.bmc.2021.116580
Staphylococcus aureus Staphylococcus aureus MIC 0.1 ug.mL-1 10.1021/np800783b
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1016/j.bmcl.2005.12.097
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1016/j.ejmech.2011.04.004
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1016/j.ejmech.2011.08.001
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.11.028
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1016/j.ejmech.2015.09.020
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1021/jm00173a028
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00100-07
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00336-08
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00923-07
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.01124-10
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.bmc.2019.06.010
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.bmc.2020.115729
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.05.009
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/S0960-894X(00)80333-9
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1021/acs.jmedchem.7b01300
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1021/jm3012728
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.00915-08
Staphylococcus aureus Staphylococcus aureus MIC 0.13 ug.mL-1 10.1016/j.bmcl.2012.08.123
Staphylococcus aureus Staphylococcus aureus MIC 0.13 ug.mL-1 10.1016/j.bmcl.2012.09.097
Staphylococcus aureus Staphylococcus aureus MIC 0.13 ug.mL-1 10.1016/j.bmcl.2013.06.048
Staphylococcus aureus Staphylococcus aureus MIC 0.13 ug.mL-1 10.1016/j.ejmech.2012.12.027
Staphylococcus aureus Staphylococcus aureus MIC 0.195 ug.mL-1 10.1128/aac.00971-08
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1016/j.bmcl.2003.12.059
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1016/j.bmcl.2005.11.061
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1016/s0960-894x(00)00106-2
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/jm00394a001
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/jm0102349
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/jm015566s
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/jm020568d
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/jm970548p
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/jm990618n
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1021/np030131o
Staphylococcus aureus Staphylococcus aureus MIC 0.2 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmc.2016.06.044
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2004.04.077
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2015.07.010
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.11.035
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2011.08.001
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2012.11.028
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2015.09.020
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/S0960-894X(01)80238-9
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/S0960-894X(01)81003-9
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jnatprod.0c01309
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/jm00403a025
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/jm3012728
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/np050438i
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/np060334n
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/np4006794
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/np8002673
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00169-10
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00206-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00313-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00481-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00570-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00801-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00915-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01091-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01247-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01376-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus MIC 0.256 ug.mL-1 10.1128/aac.01173-08
Staphylococcus aureus Staphylococcus aureus MIC 0.3 ug.mL-1 10.1021/jm980240d
Staphylococcus aureus Staphylococcus aureus MIC 0.39 ug.mL-1 10.1016/j.bmcl.2005.03.011
Staphylococcus aureus Staphylococcus aureus MIC 0.4 ug.mL-1 10.1021/jm00215a025
Staphylococcus aureus Staphylococcus aureus MIC 0.4 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 0.42 ug.mL-1 10.1016/j.bmc.2021.116580
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmc.2010.02.005
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmc.2016.10.033
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2004.03.020
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2004.06.045
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2004.12.067
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2005.10.074
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2005.12.097
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2006.08.130
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2007.04.104
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2007.08.068
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.07.007
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.07.118
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.10.109
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2011.04.004
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2012.05.110
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2015.07.010
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2018.02.047
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2010.09.060
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2011.12.039
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.9b00370
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jnatprod.0c01309
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/jm025580k
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/jm034233n
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/jm401808n
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00237-08
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00247-08
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00361-10
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.00915-08
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.01113-10
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.01398-07
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.01422-07
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1128/aac.01583-07
Staphylococcus aureus Staphylococcus aureus MIC 0.9 ug.mL-1 10.1039/C0MD00251H
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmc.2010.02.005
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2006.09.036
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2008.09.019
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/np800783b
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00206-09
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00801-08
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00985-09
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.01422-07
Staphylococcus aureus Staphylococcus aureus MIC 1.25 ug.mL-1 10.1021/np010173h
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2010.05.009
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00206-09
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00273-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00971-08
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus MIC 3.1 ug.mL-1 10.1021/jm970548p
Staphylococcus aureus Staphylococcus aureus MIC 3.12 ug.mL-1 10.1016/j.ejmech.2019.05.031
Staphylococcus aureus Staphylococcus aureus MIC 3.26 ug.mL-1 10.1128/aac.00062-07
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2004.06.045
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00846-07
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1128/aac.00923-07
Staphylococcus aureus Staphylococcus aureus MIC 6.2 ug.mL-1 10.1016/j.bmcl.2005.03.011
Staphylococcus aureus Staphylococcus aureus MIC 6.2 ug.mL-1 10.1016/s0960-894x(00)00106-2
Staphylococcus aureus Staphylococcus aureus MIC 6.2 ug.mL-1 10.1021/jm0102349
Staphylococcus aureus Staphylococcus aureus MIC 6.2 ug.mL-1 10.1021/jm990618n
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1016/j.ejmech.2016.12.060
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1021/np050438i
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1039/C0MD00251H
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00064-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00361-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00576-06
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00908-07
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00923-07
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1016/j.bmcl.2005.11.061
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2004.06.045
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1021/np300554f
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.00923-07
Staphylococcus aureus Staphylococcus aureus MIC 31.0 ug.mL-1 10.1016/j.ejmech.2019.04.043
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2008.07.007
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2008.09.013
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2020.112245
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2020.113134
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2021.113442
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/acs.jnatprod.7b00133
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1021/np800783b
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00923-07
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00985-09
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.01422-07
Staphylococcus aureus Staphylococcus aureus MIC 40.0 ug.mL-1 10.1021/jm980240d
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmc.2007.04.021
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.06.010
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmc.2020.115729
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2007.08.068
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.07.118
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.10.109
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2011.04.004
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.08.123
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.09.097
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2013.06.048
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2010.05.009
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.12.039
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2012.12.027
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/jm3012728
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/np8002673
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00169-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00464-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.01113-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.01124-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.01376-08
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1021/jm0102349
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1021/jm970548p
Staphylococcus aureus Staphylococcus aureus MIC 100.0 ug.mL-1 10.1021/jm990618n
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmcl.2004.03.020
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmcl.2004.04.077
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1016/j.bmcl.2007.08.068
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm00403a025
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm025580k
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm401808n
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm8000136
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/np050462w
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/np8002673
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/np800581s
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1128/aac.00206-09
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1128/aac.00801-08
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1128/aac.01091-09
Staphylococcus aureus Staphylococcus aureus MIC 200.0 ug.mL-1 10.1021/jm970547x
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2007.08.068
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2012.05.110
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1021/np4006794
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1128/aac.00206-09
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1128/aac.00231-08
Staphylococcus aureus Staphylococcus aureus MIC 256.0 ug.mL-1 10.1128/aac.01098-07
Staphylococcus aureus Staphylococcus aureus MIC 390.0 nM 10.1016/0960-894X(95)00122-A
Staphylococcus aureus Staphylococcus aureus MIC 400.0 ug.mL-1 10.1128/aac.01682-09
Staphylococcus aureus Staphylococcus aureus MIC 500.0 nM 10.1021/acs.jmedchem.9b00288
Staphylococcus aureus Staphylococcus aureus MIC 512.0 ug.mL-1 10.1128/aac.00846-07
Staphylococcus aureus Staphylococcus aureus MIC 512.0 ug.mL-1 10.1128/aac.00870-08
Staphylococcus aureus Staphylococcus aureus MIC 1000.0 nM 10.1021/acs.jmedchem.9b00288
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1016/j.ejmech.2010.09.060
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1128/aac.00209-07
Staphylococcus aureus Staphylococcus aureus MIC 1024.0 ug.mL-1 10.1128/aac.01583-07
Staphylococcus aureus Staphylococcus aureus MIC 1250.0 ug.mL-1 10.1016/j.bmc.2015.09.027
Staphylococcus aureus Staphylococcus aureus MIC 2048.0 ug.mL-1 10.1128/aac.00209-07
Staphylococcus aureus Staphylococcus aureus MIC 3100.0 ug.mL-1 10.1021/jm970547x
Staphylococcus aureus Staphylococcus aureus MIC 20000.0 nM 10.6019/CHEMBL4513161
Staphylococcus aureus Staphylococcus aureus MIC 128000.0 nM 10.1021/acsmedchemlett.0c00425
Staphylococcus aureus Staphylococcus aureus MIC 349000.0 nM 10.1021/np2003319
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1016/j.bmcl.2012.05.112
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1021/np4006794
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC50 0.25 ug.mL-1 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.25 ug.mL-1 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus aureus Staphylococcus aureus MIC50 0.25 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC50 0.25 ug.mL-1 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus MIC50 0.5 ug.mL-1 10.1128/aac.00100-07
Staphylococcus aureus Staphylococcus aureus MIC50 0.5 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC50 0.5 ug.mL-1 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus MIC50 1.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 2.0 ug.mL-1 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus MIC50 16.0 ug.mL-1 10.1021/jm0310232
Staphylococcus aureus Staphylococcus aureus MIC50 16.0 ug.mL-1 10.1128/aac.00100-07
Staphylococcus aureus Staphylococcus aureus MIC50 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus aureus Staphylococcus aureus MIC50 32.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC50 128.0 ug.mL-1 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus MIC80 16.0 ug.mL-1 10.1016/j.bmcl.2013.07.042
Staphylococcus aureus Staphylococcus aureus MIC=>90 0.13 ug ml-1 10.1016/j.bmcl.2013.02.016
Staphylococcus aureus Staphylococcus aureus MIC=>90 64.0 ug ml-1 10.1016/j.bmcl.2013.02.016
Staphylococcus aureus Staphylococcus aureus MIC90 0.1 ug.mL-1 10.1016/j.bmc.2012.10.009
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1021/acs.jnatprod.2c01125
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1128/aac.01453-08
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.00129-09
Staphylococcus aureus Staphylococcus aureus MIC90 4.0 ug.mL-1 10.1128/aac.00301-10
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00846-07
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.00952-09
Staphylococcus aureus Staphylococcus aureus MIC90 8.0 ug.mL-1 10.1128/aac.01351-07
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1021/jm0310232
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1128/aac.00100-07
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1016/j.ejmech.2011.05.032
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.00344-06
Staphylococcus aureus Staphylococcus aureus MIC90 32.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC90 64.0 ug.mL-1 10.1016/j.bmc.2012.10.009
Staphylococcus aureus Staphylococcus aureus MIC90 64.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus aureus Staphylococcus aureus MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Staphylococcus aureus Staphylococcus aureus MIC90 128.0 ug.mL-1 10.1128/aac.01562-06
Staphylococcus aureus Staphylococcus aureus Ratio 256.0 None 10.1016/j.bmcl.2013.06.048
Staphylococcus aureus Staphylococcus aureus Ratio 256.0 None 10.1021/jm3012728
Staphylococcus capitis Staphylococcus capitis Activity 18.0 % 10.1128/aac.01398-07
Staphylococcus capitis Staphylococcus capitis MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus capitis Staphylococcus capitis MIC 0.12 ug.mL-1 10.1128/aac.01398-07
Staphylococcus capitis Staphylococcus capitis MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus capitis Staphylococcus capitis MIC50 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus capitis Staphylococcus capitis MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus capitis Staphylococcus capitis MIC90 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus cohnii Staphylococcus cohnii MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus cohnii Staphylococcus cohnii MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus cohnii Staphylococcus cohnii MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus epidermidis Staphylococcus epidermidis Activity 7.0 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 11.0 % 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 15.0 % 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 15.0 % 10.1128/aac.01398-07
Staphylococcus epidermidis Staphylococcus epidermidis Activity 23.0 % 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 24.1 % 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 27.0 % 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 32.2 % 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 34.7 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 37.9 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 45.4 % 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 47.2 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 50.0 % 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 50.8 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 53.8 % 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 55.7 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 56.1 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 58.7 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 60.4 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 63.2 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 67.2 % 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 69.4 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 74.0 % 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 75.3 % 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 78.5 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 87.8 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 93.9 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 100.0 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 150.3 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 159.6 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 163.1 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 166.8 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 172.2 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 173.0 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 230.4 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 284.3 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity 297.8 % 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Activity nan None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 0.6 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 1.2 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 1.4 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 1.7 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 1.8 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 2.0 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 2.4 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 2.8 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 3.7 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 4.5 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 6.2 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC 6.9 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis FC nan None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis IZ 11.0 mm 10.1016/j.ejmech.2014.05.084
Staphylococcus epidermidis Staphylococcus epidermidis log10cfu 0.7 None 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis MBC 1.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MBC50 2.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MBC50 32.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MBC90 128.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.06 ug.mL-1 10.1021/jm00173a028
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.06 ug.mL-1 10.1021/jm00403a025
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.06 ug.mL-1 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.062 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.063 ug.mL-1 10.1021/jm8000136
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.12 ug.mL-1 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.12 ug.mL-1 10.1128/aac.01398-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1016/S0960-894X(00)80333-9
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1128/aac.00237-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.125 ug.mL-1 10.1128/aac.00801-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.15 ug.mL-1 10.1016/j.bmcl.2006.08.130
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.2 ug.mL-1 10.1016/j.bmcl.2003.12.059
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.2 ug.mL-1 10.1016/j.bmcl.2005.11.061
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.25 ug.mL-1 10.1021/np800783b
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2011.04.004
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.0 ug.mL-1 10.1128/aac.00062-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1128/aac.00231-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 16.0 ug.mL-1 10.1021/np4006794
Staphylococcus epidermidis Staphylococcus epidermidis MIC 16.0 ug.mL-1 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 32.0 ug.mL-1 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 40.0 ug.mL-1 10.1021/jm980240d
Staphylococcus epidermidis Staphylococcus epidermidis MIC 64.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Staphylococcus epidermidis Staphylococcus epidermidis MIC 128.0 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus epidermidis Staphylococcus epidermidis MIC 128.0 ug.mL-1 10.1021/jm00403a025
Staphylococcus epidermidis Staphylococcus epidermidis MIC 128.0 ug.mL-1 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC 250.0 nM 10.1021/acs.jmedchem.9b00288
Staphylococcus epidermidis Staphylococcus epidermidis MIC 256.0 ug.mL-1 10.1016/j.bmcl.2012.10.064
Staphylococcus epidermidis Staphylococcus epidermidis MIC 256.0 ug.mL-1 10.1021/np4006794
Staphylococcus epidermidis Staphylococcus epidermidis MIC nan None 10.1016/j.bmc.2019.03.034
Staphylococcus epidermidis Staphylococcus epidermidis MIC nan None 10.1021/np4006794
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC50 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 8.0 ug.mL-1 10.1128/aac.00952-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus epidermidis Staphylococcus epidermidis MIC90 32.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus epidermidis Staphylococcus epidermidis Ratio 1.02 None 10.1128/aac.01565-09
Staphylococcus epidermidis Staphylococcus epidermidis Ratio 2.51 None 10.1128/aac.01565-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 11.0 % 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 11.7 % 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 15.0 % 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 18.0 % 10.1128/aac.01398-07
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 21.6 % 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 23.0 % 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 27.0 % 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 48.6 % 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 50.0 % 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 51.4 % 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 74.0 % 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 78.4 % 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus Activity 88.3 % 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MBC 1.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MBC50 2.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MBC50 32.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MBC90 128.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.12 ug.mL-1 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.12 ug.mL-1 10.1128/aac.01398-07
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.125 ug.mL-1 10.1016/S0960-894X(01)81003-9
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 1.0 ug.mL-1 10.1021/np800783b
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2006.09.036
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC50 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 8.0 ug.mL-1 10.1128/aac.00952-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC90 32.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis Activity 11.0 % 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis Activity 15.0 % 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis Activity 23.0 % 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis Activity 27.0 % 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis Activity 50.0 % 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis Activity 74.0 % 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MBC 1.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MBC50 2.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MBC50 32.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MBC90 128.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus hominis Staphylococcus hominis MIC 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus hominis Staphylococcus hominis MIC50 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MIC50 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus hominis Staphylococcus hominis MIC90 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus hominis Staphylococcus hominis MIC90 32.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus intermedius Staphylococcus intermedius MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus intermedius Staphylococcus intermedius MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus intermedius Staphylococcus intermedius MIC90 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC50 8.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus lugdunensis Staphylococcus lugdunensis MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus saprophyticus Staphylococcus saprophyticus Activity 18.0 % 10.1128/aac.01398-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 0.12 ug.mL-1 10.1128/aac.01398-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 0.25 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 64.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC 128.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 0.125 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC50 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 2.0 ug.mL-1 10.1128/aac.01150-07
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Staphylococcus saprophyticus Staphylococcus saprophyticus MIC90 16.0 ug.mL-1 10.1128/aac.01398-07
Staphylococcus simulans Staphylococcus simulans Activity 15.0 % 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans Activity 23.0 % 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans Activity 27.0 % 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans Activity 50.0 % 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans Activity 74.0 % 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MBC 1.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MBC50 2.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MBC50 32.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MBC90 128.0 ug ml-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MIC 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MIC50 0.5 ug.mL-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MIC50 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MIC90 16.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus simulans Staphylococcus simulans MIC90 32.0 ug.mL-1 10.1128/aac.00624-09
Staphylococcus sp. Staphylococcus sp. Activity 17.0 % 10.1128/aac.01562-06
Staphylococcus sp. Staphylococcus sp. Activity 20.0 % 10.1128/aac.01562-06
Staphylococcus sp. Staphylococcus sp. Activity 78.0 % 10.1128/aac.01562-06
Staphylococcus sp. Staphylococcus sp. Activity 80.0 % 10.1128/aac.01562-06
Staphylococcus sp. Staphylococcus sp. MIC50 0.25 ug.mL-1 10.1128/aac.01562-06
Staphylococcus sp. Staphylococcus sp. MIC50 40.0 ug.mL-1 10.1021/jm980240d
Staphylococcus sp. Staphylococcus sp. MIC50 128.0 ug.mL-1 10.1128/aac.01562-06
Staphylococcus sp. Staphylococcus sp. MIC90 40.0 ug.mL-1 10.1021/jm980240d
Staphylococcus sp. Staphylococcus sp. MIC90 128.0 ug.mL-1 10.1128/aac.01562-06
Staphylococcus warneri Staphylococcus warneri MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Staphylococcus warneri Staphylococcus warneri MIC50 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus warneri Staphylococcus warneri MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Streptococcus Streptococcus Activity 0.0 % 10.1128/aac.00952-09
Streptococcus Streptococcus Activity 16.7 % 10.1128/aac.00952-09
Streptococcus Streptococcus Activity 25.0 % 10.1128/aac.01341-06
Streptococcus Streptococcus Activity 41.7 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 56.0 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 79.6 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 79.8 % 10.1128/aac.00952-09
Streptococcus Streptococcus Activity 82.4 % 10.1128/aac.00952-09
Streptococcus Streptococcus Activity 100.0 % 10.1128/aac.00952-09
Streptococcus Streptococcus EC50 60.0 nM None
Streptococcus Streptococcus MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC 0.06 ug.mL-1 10.1021/jm00403a025
Streptococcus Streptococcus MIC 0.1 ug 10.1021/jm00403a025
Streptococcus Streptococcus MIC 0.12 ug.mL-1 10.1021/jm00403a025
Streptococcus Streptococcus MIC 0.25 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC 0.5 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC 1.0 ug.mL-1 10.1021/jm00403a025
Streptococcus Streptococcus MIC 2.0 ug.mL-1 10.1021/jm00403a025
Streptococcus Streptococcus MIC50 0.25 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC90 2.0 ug.mL-1 10.1128/aac.01453-08
Streptococcus agalactiae Streptococcus agalactiae Activity 0.0 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae Activity 0.0 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae Activity 28.7 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae Activity 62.0 % 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae Activity 70.6 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae Activity 92.9 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae Activity 97.5 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae Activity 100.0 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae Activity 100.0 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae IZ 10.0 mm 10.1016/j.ejmech.2019.111744
Streptococcus agalactiae Streptococcus agalactiae MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC 0.016 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.05 ug.mL-1 10.1016/j.bmcl.2003.12.059
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.5 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.5 ug.mL-1 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.032 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 16.0 ug.mL-1 10.1128/aac.00336-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 64.0 ug.mL-1 10.1128/aac.01716-08
Streptococcus constellatus Streptococcus constellatus Activity 0.0 % 10.1128/aac.01845-09
Streptococcus constellatus Streptococcus constellatus Activity 7.7 % 10.1128/aac.01845-09
Streptococcus constellatus Streptococcus constellatus Activity 20.0 % 10.1128/aac.01845-09
Streptococcus constellatus Streptococcus constellatus Activity 63.0 % 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus Activity 65.0 % 10.1128/aac.01845-09
Streptococcus constellatus Streptococcus constellatus MIC 0.015 ug.mL-1 10.1128/aac.00336-08
Streptococcus constellatus Streptococcus constellatus MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus constellatus Streptococcus constellatus MIC50 nan None 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC90 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus constellatus Streptococcus constellatus MIC90 nan None 10.1128/aac.01398-07
Streptococcus equinus Streptococcus equinus MIC 0.05 ug.mL-1 10.1016/j.bmcl.2003.12.059
Streptococcus equinus Streptococcus equinus MIC 0.06 ug.mL-1 10.1128/aac.00603-06
Streptococcus equi subsp. zooepidemicus Streptococcus equi subsp. zooepidemicus MIC 0.14 ug.mL-1 10.1128/aac.00062-07
Streptococcus intermedius Streptococcus intermedius Activity 16.7 % 10.1128/aac.01845-09
Streptococcus intermedius Streptococcus intermedius Activity 28.6 % 10.1128/aac.01845-09
Streptococcus intermedius Streptococcus intermedius Activity 34.4 % 10.1128/aac.01845-09
Streptococcus intermedius Streptococcus intermedius Activity 50.0 % 10.1128/aac.01845-09
Streptococcus intermedius Streptococcus intermedius Activity 63.0 % 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC50 nan None 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC90 nan None 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis Activity 63.0 % 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus mitis Streptococcus mitis MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus mitis Streptococcus mitis MIC50 nan None 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC90 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus mitis Streptococcus mitis MIC90 nan None 10.1128/aac.01398-07
Streptococcus mutans Streptococcus mutans Activity 0.78 ug ml-1 10.1016/j.bmcl.2009.12.020
Streptococcus mutans Streptococcus mutans MBC 1.5 ug ml-1 10.1016/j.bmcl.2009.12.020
Streptococcus oralis Streptococcus oralis Activity 63.0 % 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC50 nan None 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC90 nan None 10.1128/aac.01398-07
Streptococcus pasteurianus Streptococcus pasteurianus MIC 512.0 ug.mL-1 10.1128/aac.00603-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.25 ug ml-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 1.0 ug ml-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 5.3 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 6.9 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 9.9 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 11.6 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 13.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 14.9 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 17.2 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 20.0 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 20.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 21.1 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 26.4 % 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 26.5 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 28.4 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 30.6 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 32.4 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 40.8 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 41.2 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 41.9 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 42.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 43.3 min 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 50.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 52.5 min 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 53.0 min 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 58.2 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 58.8 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 62.5 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 63.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 64.4 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 67.3 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 68.0 % 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 71.6 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 72.0 % 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 72.4 % 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 75.5 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 75.8 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 78.8 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 78.9 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 80.0 % 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 83.5 % 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 84.5 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 88.1 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 88.6 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 89.1 % 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 90.9 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 95.1 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 129.0 ug ml-1 10.1128/aac.00187-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1016/j.bmcl.2006.08.076
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.01459-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity nan None 10.1128/aac.01662-09
Streptococcus pneumoniae Streptococcus pneumoniae ED50 1.48 mg.kg-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae ED50 44.0 mg.kg-1 10.1021/jm00173a028
Streptococcus pneumoniae Streptococcus pneumoniae ED50 100.0 mg.kg-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae FC 2.57 None 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae FC 4.98 None 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae IC50 37.0 nM 10.1016/j.bmcl.2020.127071
Streptococcus pneumoniae Streptococcus pneumoniae IC50 51.0 nM 10.1016/j.bmcl.2020.127071
Streptococcus pneumoniae Streptococcus pneumoniae IC50 120.0 nM 10.1021/jm0102349
Streptococcus pneumoniae Streptococcus pneumoniae IC50 500000.0 nM 10.1021/jm0102349
Streptococcus pneumoniae Streptococcus pneumoniae IC50 nan None 10.1016/j.bmcl.2020.127071
Streptococcus pneumoniae Streptococcus pneumoniae MBC 2.0 ug ml-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MBC 4.0 ug ml-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MBC 8.0 ug ml-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MBC 16.0 ug ml-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MBC 32.0 ug ml-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MBC 64.0 ug ml-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.0025 ug.mL-1 10.1016/j.bmc.2010.08.035
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.0025 ug.mL-1 10.1021/jm901107f
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1021/jm00173a028
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1128/aac.00723-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1016/j.bmcl.2004.03.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1021/jm025580k
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.02 ug.mL-1 10.1016/j.bmc.2016.06.044
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.02 ug.mL-1 10.1016/S0960-894X(01)80238-9
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1016/j.bmcl.2005.11.061
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.bmcl.2004.04.077
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.bmcl.2010.04.051
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.bmcl.2010.08.030
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.bmcl.2011.04.078
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.ejmech.2010.11.035
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.ejmech.2011.08.001
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.ejmech.2012.11.028
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1016/j.ejmech.2015.09.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1021/acs.jmedchem.9b00370
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01459-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.032 ug.mL-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.049 ug.mL-1 10.1016/j.bmcl.2005.11.061
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2004.12.067
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2005.03.011
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2005.10.074
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2005.12.097
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2006.09.036
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2007.04.104
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2008.07.118
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2008.10.109
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/s0960-894x(00)00106-2
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/S0960-894X(00)80333-9
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1021/jm0102349
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1021/jm034233n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1021/jm970548p
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1021/jm990618n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.062 ug.mL-1 10.1016/j.bmcl.2012.10.064
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.063 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.08 ug.mL-1 10.1021/jm980240d
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.094 ug.mL-1 10.1128/aac.01153-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1021/jm015566s
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1021/jm020568d
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1016/j.bmcl.2008.07.007
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1016/j.ejmech.2011.04.004
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1016/j.bmc.2007.04.021
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1016/j.bmcl.2011.10.101
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.19 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1016/j.bmcl.2011.10.101
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.05.009
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.09.060
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1016/j.bmcl.2011.10.101
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1016/j.ejmech.2010.05.009
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01270-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.56 ug.mL-1 10.1021/jm015566s
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1021/np800783b
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01270-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01459-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 3.12 ug.mL-1 10.1016/j.bmcl.2005.11.061
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2004.03.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2004.04.077
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2004.12.067
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2005.10.074
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2005.12.097
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2006.09.036
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2007.04.104
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2008.07.118
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/j.bmcl.2008.10.109
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1021/jm025580k
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 6.0 ug.mL-1 10.1021/jm00403a025
Streptococcus pneumoniae Streptococcus pneumoniae MIC 6.25 ug.mL-1 10.1016/j.bmcl.2005.11.061
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.bmc.2007.04.021
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2010.04.051
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.bmcl.2011.10.101
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.ejmech.2010.11.035
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.ejmech.2011.04.004
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.ejmech.2011.08.001
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.ejmech.2012.11.028
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/j.ejmech.2015.09.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1021/jm034233n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01270-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 12.5 ug.mL-1 10.1016/j.bmcl.2005.11.061
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2004.12.067
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2005.03.011
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2005.10.074
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2005.12.097
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2006.09.036
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2007.04.104
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1016/s0960-894x(00)00106-2
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1021/jm970548p
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1021/jm990618n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01756-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 24.0 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1016/j.ejmech.2010.09.060
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1021/jm0102349
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01270-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 40.0 ug.mL-1 10.1021/jm980240d
Streptococcus pneumoniae Streptococcus pneumoniae MIC 60.0 ug.mL-1 10.1021/jm970547x
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmc.2016.10.033
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.07.118
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.10.109
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1021/jm034233n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1021/np060334n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 100.0 nM 10.1016/0960-894X(95)00122-A
Streptococcus pneumoniae Streptococcus pneumoniae MIC 100.0 ug.mL-1 10.1021/jm015566s
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.bmcl.2004.03.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.bmcl.2004.04.077
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.bmcl.2005.03.011
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.bmcl.2010.04.051
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2010.11.035
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2011.04.004
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2011.08.001
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2012.11.028
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/j.ejmech.2015.09.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1016/s0960-894x(00)00106-2
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1021/jm025580k
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1021/jm8000136
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1021/jm970548p
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1021/jm990618n
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01457-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 129.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.bmcl.2010.04.051
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.bmcl.2012.10.064
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.ejmech.2010.11.035
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.ejmech.2011.04.004
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.ejmech.2011.08.001
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.ejmech.2012.11.028
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1016/j.ejmech.2015.09.020
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1021/acs.jmedchem.9b00370
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01016-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01066-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01074-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01153-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 256.0 ug.mL-1 10.1128/aac.01459-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8000.0 ug.mL-1 10.1021/jm970547x
Streptococcus pneumoniae Streptococcus pneumoniae MIC 128000.0 ug.mL-1 10.1021/jm970547x
Streptococcus pneumoniae Streptococcus pneumoniae MIC nan None 10.1016/j.bmc.2019.03.034
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01017-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 32.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.00723-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 64.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 128000.0 nM 10.1016/j.bmcl.2010.01.153
Streptococcus pneumoniae Streptococcus pneumoniae MIC80 8.0 ug.mL-1 10.1016/j.bmcl.2013.07.042
Streptococcus pneumoniae Streptococcus pneumoniae MIC80 16.0 ug.mL-1 10.1016/j.bmcl.2013.07.042
Streptococcus pneumoniae Streptococcus pneumoniae MIC>90 0.1 ug ml-1 10.1021/np400145u
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.125 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01017-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00157-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 32.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.00723-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 64.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 128.0 ug.mL-1 10.1128/aac.00107-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 128.0 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MST 5.27 day 10.1128/aac.01459-06
Streptococcus pneumoniae Streptococcus pneumoniae MST 6.78 day 10.1128/aac.01459-06
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 1.5 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 13.6 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity 19.0 % 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes Activity 80.0 % 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes Activity 80.6 % 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes Activity 86.3 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity 89.0 % 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes Activity 98.5 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 99.2 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity nan None 10.1016/j.bmcl.2006.08.076
Streptococcus pyogenes Streptococcus pyogenes Activity nan None 10.1128/aac.01662-09
Streptococcus pyogenes Streptococcus pyogenes ED50 21.0 mg.kg-1 10.1021/jm00173a028
Streptococcus pyogenes Streptococcus pyogenes MBC50 8.0 mg/L 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MBC90 32.0 mg/L 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MIC 0.008 ug.mL-1 10.1021/jm8000136
Streptococcus pyogenes Streptococcus pyogenes MIC 0.008 ug.mL-1 10.1128/aac.00723-10
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1016/j.bmcl.2004.03.020
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1016/j.bmcl.2008.07.118
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1016/j.bmcl.2008.10.109
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1016/j.bmcl.2011.10.101
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1021/jm00173a028
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1021/jm025580k
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1016/j.bmcl.2005.03.011
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1016/j.ejmech.2010.11.035
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1016/j.ejmech.2012.11.028
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1016/s0960-894x(00)00106-2
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1016/S0960-894X(01)81003-9
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1021/jm970548p
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1021/np800783b
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.031 ug.mL-1 10.1016/j.bmcl.2012.10.064
Streptococcus pyogenes Streptococcus pyogenes MIC 0.05 ug.mL-1 10.1016/j.bmcl.2003.12.059
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1016/S0960-894X(00)80333-9
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1021/jm990618n
Streptococcus pyogenes Streptococcus pyogenes MIC 0.08 ug.mL-1 10.1021/jm980240d
Streptococcus pyogenes Streptococcus pyogenes MIC 0.12 ug.mL-1 10.1016/j.ejmech.2015.09.020
Streptococcus pyogenes Streptococcus pyogenes MIC 0.125 ug.mL-1 10.1016/j.bmc.2007.04.021
Streptococcus pyogenes Streptococcus pyogenes MIC 0.125 ug.mL-1 10.1128/aac.00604-06
Streptococcus pyogenes Streptococcus pyogenes MIC 0.2 ug.mL-1 10.1039/C0MD00251H
Streptococcus pyogenes Streptococcus pyogenes MIC 0.25 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.32 ug.mL-1 10.1128/aac.00062-07
Streptococcus pyogenes Streptococcus pyogenes MIC 0.5 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.5 ug.mL-1 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes MIC 1.0 ug.mL-1 10.1039/C0MD00251H
Streptococcus pyogenes Streptococcus pyogenes MIC 2.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC 4.0 ug.mL-1 10.1016/j.ejmech.2010.11.035
Streptococcus pyogenes Streptococcus pyogenes MIC 4.0 ug.mL-1 10.1016/j.ejmech.2012.11.028
Streptococcus pyogenes Streptococcus pyogenes MIC 4.0 ug.mL-1 10.1128/aac.01065-08
Streptococcus pyogenes Streptococcus pyogenes MIC 8.0 ug.mL-1 10.1016/j.bmc.2007.04.021
Streptococcus pyogenes Streptococcus pyogenes MIC 8.0 ug.mL-1 10.1016/j.bmcl.2004.03.020
Streptococcus pyogenes Streptococcus pyogenes MIC 8.0 ug.mL-1 10.1021/jm025580k
Streptococcus pyogenes Streptococcus pyogenes MIC 8.0 ug.mL-1 10.1128/aac.01065-08
Streptococcus pyogenes Streptococcus pyogenes MIC 16.0 ug.mL-1 10.1016/j.bmcl.2008.07.118
Streptococcus pyogenes Streptococcus pyogenes MIC 16.0 ug.mL-1 10.1016/j.bmcl.2008.10.109
Streptococcus pyogenes Streptococcus pyogenes MIC 16.0 ug.mL-1 10.1021/jm034233n
Streptococcus pyogenes Streptococcus pyogenes MIC 20.0 ug.mL-1 10.1021/jm970547x
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1016/s0960-894x(00)00106-2
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1021/jm970548p
Streptococcus pyogenes Streptococcus pyogenes MIC 32.0 ug.mL-1 10.1021/jm990618n
Streptococcus pyogenes Streptococcus pyogenes MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.07.118
Streptococcus pyogenes Streptococcus pyogenes MIC 64.0 ug.mL-1 10.1016/j.bmcl.2008.10.109
Streptococcus pyogenes Streptococcus pyogenes MIC 64.0 ug.mL-1 10.1021/jm034233n
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1016/j.bmcl.2004.03.020
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1016/j.bmcl.2005.03.011
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1016/j.ejmech.2015.09.020
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1016/s0960-894x(00)00106-2
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1016/S0960-894X(01)81003-9
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1021/jm025580k
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1021/jm970548p
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1021/jm990618n
Streptococcus pyogenes Streptococcus pyogenes MIC 128.0 ug.mL-1 10.1128/aac.01484-06
Streptococcus pyogenes Streptococcus pyogenes MIC 256.0 ug.mL-1 10.1016/j.bmcl.2012.10.064
Streptococcus pyogenes Streptococcus pyogenes MIC 256.0 ug.mL-1 10.1016/j.ejmech.2012.02.002
Streptococcus pyogenes Streptococcus pyogenes MIC 3100.0 ug.mL-1 10.1021/jm970547x
Streptococcus pyogenes Streptococcus pyogenes MIC 100000.0 ug.mL-1 10.1021/jm970547x
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.00723-10
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.25 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 4.0 ug.mL-1 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MIC50 4.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 8.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 8.0 ug.mL-1 10.1128/aac.01017-06
Streptococcus pyogenes Streptococcus pyogenes MIC50 8.0 ug.mL-1 10.1128/aac.01065-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 16.0 ug.mL-1 10.1128/aac.01065-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 16.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 64.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC80 32.0 ug.mL-1 10.1016/j.bmcl.2013.07.042
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.125 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.25 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC90 2.0 ug.mL-1 10.1128/aac.00723-10
Streptococcus pyogenes Streptococcus pyogenes MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 2.0 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 8.0 ug.mL-1 10.1128/aac.00344-06
Streptococcus pyogenes Streptococcus pyogenes MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 16.0 ug.mL-1 10.1128/aac.01017-06
Streptococcus pyogenes Streptococcus pyogenes MIC90 16.0 ug.mL-1 10.1128/aac.01065-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 32.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 64.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes serotype M1 Streptokinase A EC50 60.0 nM None
Streptococcus sanguinis Streptococcus sanguinis Activity 25.0 ug ml-1 10.1016/j.bmcl.2009.12.020
Streptococcus sanguinis Streptococcus sanguinis MBC 50.0 ug ml-1 10.1016/j.bmcl.2009.12.020
Streptococcus sanguinis Streptococcus sanguinis MIC 0.03 ug.mL-1 10.1021/jm00403a025
Streptococcus sanguinis Streptococcus sanguinis MIC 12.5 ug.mL-1 10.1016/j.bmcl.2009.12.020
Streptococcus sp. Streptococcus sp. Activity 54.0 % 10.1128/aac.01325-07
Streptococcus sp. Streptococcus sp. MIC 0.064 ug.mL-1 10.1128/aac.01325-07
Streptococcus sp. Streptococcus sp. MIC 4.0 ug.mL-1 10.1128/aac.01428-06
Streptococcus sp. Streptococcus sp. MIC 128.0 ug.mL-1 10.1128/aac.01428-06
Streptococcus sp. Streptococcus sp. MIC 256.0 ug.mL-1 10.1128/aac.01325-07
Streptococcus sp. Streptococcus sp. MIC50 5.0 ug.mL-1 10.1021/jm980240d
Streptococcus sp. Streptococcus sp. MIC50 20.0 ug.mL-1 10.1021/jm980240d
Streptococcus sp. Streptococcus sp. MIC90 40.0 ug.mL-1 10.1021/jm980240d
Streptococcus sp. 'group A' Streptococcus sp. 'group A' Activity 16.1 % 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' Activity 83.3 % 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' EC50 60.0 nM None
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC 0.12 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC50 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC50 0.12 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC90 0.06 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC90 4.0 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' Activity 26.0 % 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' Activity 73.0 % 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.12 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.12 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 2.0 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC50 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC50 0.12 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC90 0.5 ug.mL-1 10.1128/aac.00100-07
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC90 4.0 ug.mL-1 10.1128/aac.00129-09
Streptococcus suis Streptococcus suis MIC 4.0 ug.mL-1 10.1128/aac.00965-10
Streptococcus suis Streptococcus suis MIC 256.0 ug.mL-1 10.1128/aac.00965-10
Streptococcus viridans Streptococcus viridans Activity 21.4 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 40.2 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 58.6 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 63.0 % 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans Activity 71.4 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.015 ug.mL-1 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 128.0 ug 10.1021/jm00403a025
Streptococcus viridans Streptococcus viridans MIC50 0.03 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans MIC50 0.06 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 2.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 nan None 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans MIC90 1.0 ug.mL-1 10.1128/aac.00100-07
Streptococcus viridans Streptococcus viridans MIC90 4.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC90 nan None 10.1128/aac.01398-07
Toxoplasma gondii Toxoplasma gondii IC50 93000.0 nM 10.1021/jm101593u
Xanthomonas campestris Xanthomonas campestris IZ nan None 10.1021/acs.jnatprod.8b00200
Yarrowia lipolytica Yarrowia lipolytica MIC nan None 10.1016/j.bmcl.2008.09.013
None ADMET Activity 0.137 % 10.1016/j.ejmech.2020.112465
None ADMET Activity 40.0 % 10.1128/aac.00729-05
None ADMET Activity 396.0 omegacm2 10.1016/j.ejmech.2020.112465
None ADMET Activity nan None 10.1021/jm201082a
None ADMET Activity nan None 10.1128/aac.00140-07
None ADMET Binding 80.0 % 10.1021/jm00107a036
None ADMET CL 2.1e-05 mL.min-1.g-1 10.1124/dmd.111.039180
None ADMET CL 0.021 uL/min 10.1124/dmd.111.039180
None ADMET CL 5.6 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CL 7.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 14.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 21.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET CL 73.0 mL.min-1.kg-1 10.1002/jps.20373
None ADMET Cmax 1120.0 nM None
None ADMET DNAUC 1.32 kg.min/L 10.1080/00498250400028197
None ADMET DNAUC 1.88 kg.min/L 10.1080/00498250400028197
None ADMET DNAUC 31.38 kg.min/L 10.1080/00498250400028197
None ADMET DNAUC 36.8 kg.min/L 10.1080/00498250400028197
None ADMET Drug excretion 5.0 % 10.1124/dmd.112.049312
None ADMET Drug excretion 13.0 % 10.1124/dmd.112.049312
None ADMET Drug excretion 30.0 % 10.1124/dmd.112.049312
None ADMET Ionization 96.0 % 10.1021/jm00107a036
None ADMET Log K 0.35 None 10.1021/jm960436i
None ADMET logP(lung) 1.62 None 10.1016/j.ejmech.2007.04.002
None ADMET MRT 2.8 hr 10.1124/dmd.108.020479
None ADMET Papp 0.0324 10^-6 cm/s 10.1016/j.ejmech.2020.112465
None ADMET Papp 0.17 10'-6 cm/s 10.1021/acs.jmedchem.8b02032
None ADMET Papp 0.19 ucm/s 10.1021/acs.jmedchem.8b00819
None ADMET Papp 0.2 10^-6 cm/s 10.1016/j.ejmech.2022.114118
None ADMET Papp 0.3 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 0.35 10'-6 cm/s 10.1021/acs.jmedchem.9b00952
None ADMET Papp 0.6 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 1.0 10'-6 cm/s 10.1021/acs.jmedchem.8b01259
None ADMET Papp 1.1 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 1.2 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 1.7 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 3.0 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 6.8 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 10.4 10'-6 cm/s 10.1021/acs.jmedchem.9b00952
None ADMET Papp 13.39 10'-6 cm/s 10.1021/acs.jmedchem.8b02032
None ADMET Papp 15.11 ucm/s 10.1021/acs.jmedchem.8b00819
None ADMET Papp 17.5 10^-6 cm/s 10.1016/j.ejmech.2022.114118
None ADMET pCF 0.014 None 10.1021/jm960436i
None ADMET pNF 1.494 None 10.1021/jm960436i
None ADMET PPB 19.0 % 10.1128/aac.00971-08
None ADMET Ratio 0.0 None 10.1124/dmd.110.034629
None ADMET Ratio 0.5 None 10.1124/dmd.110.034629
None ADMET Ratio 1.0 None 10.1128/aac.00971-08
None ADMET Ratio 2.7 None 10.1124/dmd.110.034629
None ADMET Ratio 6.0 None 10.1124/dmd.110.034629
None ADMET Ratio 7.1 None 10.1124/dmd.110.034629
None ADMET Ratio 15.0 None 10.1124/dmd.110.034629
None ADMET Ratio 16.0 None 10.1124/dmd.110.034629
None ADMET Ratio 43.0 None 10.1124/dmd.110.034629
None ADMET Ratio 62.9 None 10.1016/j.ejmech.2022.114118
None ADMET Ratio 67.0 None 10.1124/dmd.110.034629
None ADMET Ratio 72.0 None 10.1124/dmd.110.034629
None ADMET Ratio 78.76 None 10.1021/acs.jmedchem.8b02032
None ADMET Ratio 79.53 None 10.1021/acs.jmedchem.8b00819
None ADMET Ratio 88.0 None 10.1124/dmd.110.034629
None ADMET Ratio 97.0 None 10.1124/dmd.110.034629
None ADMET Ratio 251.0 None 10.1124/dmd.110.034629
None ADMET Stability 1.0 % 10.1021/acs.jmedchem.1c01730
None ADMET T1/2 0.3833 hr 10.1016/j.bmcl.2008.10.071
None ADMET T1/2 0.4 hr 10.1021/jm801332q
None ADMET T1/2 0.4667 hr 10.1021/acs.jmedchem.1c01730
None ADMET T1/2 2.0 hr 10.1124/dmd.108.020479
None ADMET Vdss 0.89 L.kg-1 10.1002/jps.20373
None ADMET Vdss 0.93 L.kg-1 10.1002/jps.20373
None ADMET Vdss 0.95 L.kg-1 10.1124/dmd.108.020479
None ADMET Vdss 2.7 L.kg-1 10.1002/jps.20373
None ADMET Vdss 9.3 mL/min/kg 10.1002/jps.20373
None Erythrocyte HC10 20.0 uM 10.6019/CHEMBL4513161
None Hepatocyte CL 26.0 uL.min-1.(10^6cells)-1 10.1124/dmd.112.045732
None Hepatocyte CL 35.0 uL.min-1.(10^6cells)-1 10.1124/dmd.112.045732
None Hepatocyte Km 3500.0 nM 10.1124/dmd.112.045732
None Hepatocyte Km 5500.0 nM 10.1124/dmd.112.045732
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 7.3 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 3.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx1000865
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity Hepatotoxicity nan None 10.1124/dmd.110.035113
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports nan None 10.2174/1570163043334794
None Hepatotoxicity LTKB_BD DILI severity score 5.0 None 10.1016/j.drudis.2011.05.007
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 7.9 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 8.5 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Keratinocyte Activity nan None 10.1128/aac.00140-07
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00898-09
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity 11.1 % 10.1128/aac.01845-09
None NON-PROTEIN TARGET Activity 16.0 ug ml-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET Activity 16.7 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity 18.0 % 10.1128/aac.01398-07
None NON-PROTEIN TARGET Activity 52.2 % 10.1128/aac.01845-09
None NON-PROTEIN TARGET Activity 57.5 % 10.1128/aac.01845-09
None NON-PROTEIN TARGET Activity 79.8 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity 82.4 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity 97.0 % 10.1016/j.bmc.2010.08.035
None NON-PROTEIN TARGET Activity 100.0 % 10.1128/aac.00898-09
None NON-PROTEIN TARGET Activity 100.0 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00729-05
None NON-PROTEIN TARGET EC50 1200.0 nM 10.1016/j.bmc.2010.08.035
None NON-PROTEIN TARGET Fu 0.1 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 3.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 19.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 38.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC20 30.0 ug ml-1 10.1128/aac.00729-05
None NON-PROTEIN TARGET IC50 180.0 ug.mL-1 10.1128/aac.00729-05
None NON-PROTEIN TARGET IZ 23.0 mm 10.1128/aac.00898-09
None NON-PROTEIN TARGET IZ 26.11 mm 10.1007/s00044-013-0755-5
None NON-PROTEIN TARGET MBC 1.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 2.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC 4.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MBC90 4.0 ug ml-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.001 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.0079 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.008 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.015 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC 0.015 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC 0.0156 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 0.0312 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1021/jm0102349
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.00481-08
None NON-PROTEIN TARGET MIC 0.064 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 0.09 ug.mL-1 10.1128/aac.00062-07
None NON-PROTEIN TARGET MIC 0.12 ug.mL-1 10.1128/aac.01383-07
None NON-PROTEIN TARGET MIC 0.12 ug.mL-1 10.1128/aac.01398-07
None NON-PROTEIN TARGET MIC 0.125 ug.mL-1 10.1128/aac.00062-07
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.01383-07
None NON-PROTEIN TARGET MIC 0.38 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.01584-07
None NON-PROTEIN TARGET MIC 0.98 ug.mL-1 10.1128/aac.00261-06
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01052-07
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.01383-07
None NON-PROTEIN TARGET MIC 1.9 ug.mL-1 10.1128/aac.00261-06
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.01052-07
None NON-PROTEIN TARGET MIC 3.9 ug.mL-1 10.1128/aac.00261-06
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1021/np300554f
None NON-PROTEIN TARGET MIC 4.0 ug.mL-1 10.1128/aac.01349-08
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1021/jm0102349
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01052-07
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01349-08
None NON-PROTEIN TARGET MIC 15.6 ug.mL-1 10.1128/aac.00261-06
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1021/jm0102349
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01052-07
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.00169-10
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01052-07
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01349-08
None NON-PROTEIN TARGET MIC 64.0 ug.mL-1 10.1128/aac.01678-09
None NON-PROTEIN TARGET MIC 128.0 ug.mL-1 10.1021/jm0102349
None NON-PROTEIN TARGET MIC 128.0 ug.mL-1 10.1128/aac.00695-08
None NON-PROTEIN TARGET MIC 128.0 ug.mL-1 10.1128/aac.01678-09
None NON-PROTEIN TARGET MIC 256.0 ug.mL-1 10.1128/aac.01584-07
None NON-PROTEIN TARGET MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC50 0.032 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC50 0.5 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC50 0.5 ug.mL-1 10.1128/aac.01584-07
None NON-PROTEIN TARGET MIC50 1.0 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.01584-07
None NON-PROTEIN TARGET MIC50 16.0 ug.mL-1 10.1128/aac.01398-07
None NON-PROTEIN TARGET MIC50 128.0 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC50 nan None 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 0.0312 ug.mL-1 10.1128/aac.01247-08
None NON-PROTEIN TARGET MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC90 0.12 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 0.125 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 0.5 ug.mL-1 10.1128/aac.01584-07
None NON-PROTEIN TARGET MIC90 1.0 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 1.5 ug.mL-1 10.1128/aac.00630-09
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC90 2.0 ug.mL-1 10.1128/aac.01584-07
None NON-PROTEIN TARGET MIC90 4.0 ug.mL-1 10.1128/aac.00849-08
None NON-PROTEIN TARGET MIC90 4.0 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.01398-07
None NON-PROTEIN TARGET MIC90 128.0 ug.mL-1 10.1128/aac.00898-09
None NON-PROTEIN TARGET MIC90 nan None 10.1128/aac.00849-08
None NON-PROTEIN TARGET Range 16.0 ug ml-1 10.1021/jm0310232
None No relevant target CLogP 0.0 None 10.1021/jm960436i
None No relevant target CLogP 0.653 None 10.1021/jm960436i
None No relevant target CLogP 3.06 None 10.1021/jm960436i
None No relevant target LogD -3.9 None 10.1021/acs.jmedchem.8b01259
None No relevant target LogD 1.26 None 10.1021/jm00169a014
None No relevant target LogD 1.58 None 10.1021/jm960436i
None No relevant target LogD nan None 10.1016/j.bmcl.2023.129331
None No relevant target Log Kmemb -0.5 None 10.1021/jm0309001
None No relevant target LogP 2.01 None 10.1016/j.bmcl.2010.08.145
None No relevant target LogP 2.5 None 10.1021/jm021012t
None No relevant target LogP 2.54 None 10.1016/j.bmcl.2010.08.145
None No relevant target LogP 50.0 None 10.1021/jm00107a036
None No relevant target pKa 8.8 None 10.1007/s11095-013-1232-z
None No relevant target pKa 8.8 None 10.1021/jm00107a036
None No relevant target pKa1 8.88 None 10.1021/jm960436i
None No relevant target T1/2 8.25 hr 10.1016/j.bmcl.2018.07.019
None Nucleic Acid Activity nan None 10.1128/aac.01425-08
None Nucleic Acid Inhibition 0.0 % 10.1021/jm00129a027
None Nucleic Acid Inhibition 3.0 % 10.1021/jm00129a027
None Osteoblast Activity nan None 10.1128/aac.00729-05
None Osteoblast IC20 11.0 ug ml-1 10.1128/aac.00729-05
None Osteoblast IC20 210.0 ug ml-1 10.1128/aac.00729-05
None Osteoblast IC50 400.0 ug.mL-1 10.1128/aac.00729-05
None Phospholipidosis Maximum test concentration that did not exhibit cytotoxicity 50.0 uM None
None Phospholipidosis Phospholipidosis nan None 10.1021/ci6004542
None Phospholipidosis Phospholipidosis nan None 10.1021/mp100103e
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Phospholipidosis Phospholipidosis as % of positive control 61.9 % None
None Ribosome Activity nan None 10.1021/acs.jnatprod.7b00133
None Unchecked Activity nan None 10.1128/aac.01425-08
None Unchecked Hepatotoxicity (acute) 72.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 55.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 20.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 2130.0 nM 10.1128/aac.00672-07
None Unchecked IC50 63000.0 nM 10.1016/j.bmcl.2019.02.028
None Unchecked IC50 100000.0 nM None
None Unchecked IC50 nan None 10.1016/j.bmc.2015.07.062
None Unchecked IC50 nan None None
None Unchecked Inhibition nan % 10.1016/j.bmcl.2014.12.010
None Unchecked Inhibition nan % 10.1021/acs.jnatprod.7b00133
None Unchecked Inhibition nan % 10.1128/aac.00620-10
None Unchecked Kcat 0.022 /s 10.1128/aac.01570-09
None Unchecked Kcat 0.279 /s 10.1128/aac.01570-09
None Unchecked Kcat 0.634 /s 10.1128/aac.01570-09
None Unchecked Kcat/Km 1.07 10'4/s/M 10.1128/aac.01570-09
None Unchecked Kcat/Km 1.16 10'1/s/M 10.1128/aac.01570-09
None Unchecked Kcat/Km 7.52 10'3/s/M 10.1128/aac.01570-09
None Unchecked Kd 6110.0 nM 10.1016/j.bmc.2015.07.062
None Unchecked Kd 6510.0 nM 10.1016/j.bmc.2015.07.062
None Unchecked Kd 8730.0 nM 10.1016/j.bmc.2015.07.062
None Unchecked Kd 27400.0 nM 10.1016/j.bmc.2015.07.062
None Unchecked Kd 30700.0 nM 10.1016/j.bmc.2015.07.062
None Unchecked Ki nan None None
None Unchecked Km 37200.0 nM 10.1128/aac.01570-09
None Unchecked Km 59200.0 nM 10.1128/aac.01570-09
None Unchecked Km 1890000.0 nM 10.1128/aac.01570-09
None Unchecked MIC 0.5 ug.mL-1 10.1021/jm00403a025
None Unchecked MIC 100000.0 ug.mL-1 10.1021/jm970547x
None Unchecked MIC50 0.6 ug.mL-1 10.1021/jm980240d
None Unchecked MIC50 40.0 ug.mL-1 10.1021/jm980240d
None Unchecked MIC90 40.0 ug.mL-1 10.1021/jm980240d
None Unchecked Potency 3162.3 nM None
None Unchecked Ratio 1.4 None 10.1016/j.bmc.2015.07.062
None Unchecked Ratio 5.0 None 10.1016/j.bmc.2015.07.062
None Unchecked Ratio IC50/EC50 32.5 None 10.1021/jm901107f
None Unchecked Selectivity Index nan None 10.1016/j.bmcl.2019.03.038
None Unchecked Time nan None 10.1128/aac.00620-10
None Unchecked TIME 0.005556 hr 10.1128/aac.00620-10

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT010276 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(O)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.C[33S]>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O None
AKRT010277 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(O)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.C[SAH]>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O RXN-12923
AKRT010280 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@H]1C>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O RXN-12926
AKRT010281 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2OP(=O)(O)O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O None
AKRT010282 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O>>CC[C@H](O)[C@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O)[C@@H](C)[C@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@@H](C)C(=O)O RXN-21071
AKRT010283 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O>>CC[C@H]1OC(=O)[C@@H]2COC3(C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)O[C@H]2[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O R05519
AKRT010284 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2OP(=O)(O)O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O enzymemap_43351