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Benzylpenicillin

AlkaPlorer ID: AK003445

Synonym: 'MLS001032123', 'SMR000538912', 'MLS000766897', 'MLS001173382', 'MLS001076462', 'SMR000059004', 'MLSMR', 'MLS000069426', 'Benzylpenicillin', 'Penicillin G potassium'

IUPAC Name: N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl]-2-phenylethanimidate

Structure

SMILES: CC1(C)S[C@@H]2[C@H](N=C([O-])CC3=CC=CC=C3)C(=O)N2[C@H]1C(=O)O

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InChI: InChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/p-1/t11-,12+,14-/m1/s1

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InChIKey: JGSARLDLIJGVTE-MBNYWOFBSA-M

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Properties Information

Molecule Weight: 333.38900000000007

TPSA？: 93.03000000000002

MolLogP？: 0.5034000000000001

Number of H-Donors: 1

Number of H-Acceptors: 5

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter baumannii Acinetobacter baumannii MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Acinetobacter baumannii Acinetobacter baumannii MIC 128000.0 nM 10.1021/acs.jmedchem.1c00614
Acinetobacter baumannii Acinetobacter baumannii MIC nan None 10.1016/j.bmcl.2011.06.081
Acinetobacter baumannii ADC-11 Kcat 45.0 /s 10.1128/aac.00050-10
Acinetobacter baumannii ADC-11 Kcat/Km 4.0 /uM/s 10.1128/aac.00050-10
Acinetobacter baumannii ADC-11 Km 12000.0 nM 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Kcat 15.0 /s 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Kcat/Km 5.0 /uM/s 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase ADC-33 Km 3000.0 nM 10.1128/aac.00050-10
Acinetobacter baumannii Beta-lactamase OXA-23 Activity 68.0 % 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Activity 120.0 % 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Activity 200.0 % 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Activity 12000.0 % 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Kcat 240.0 /s 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Kcat 530.0 /s 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Kcat/Km 8.9 /s/microM 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Kcat/Km 41.0 /s/microM 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Km 13000.0 nM 10.1128/aac.01004-09
Acinetobacter baumannii Beta-lactamase OXA-23 Km 27000.0 nM 10.1128/aac.01004-09
Actinomadura sp. R39 D-alanyl-D-alanine carboxypeptidase Inhibition nan % 10.1016/j.ejmech.2008.10.016
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Kcat 5.0 /s 10.1128/aac.01585-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Kcat/Km 25.0 /uM/s 10.1128/aac.01585-09
Aeromonas allosaccharophila Extended-spectrum beta-lactamase PER-6 Km 200000.0 nM 10.1128/aac.01585-09
Aeromonas caviae IMP-19 Kcat 1011.0 /s 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Kcat/Km 4.91 None 10.1128/aac.01462-06
Aeromonas caviae IMP-19 Km 206000.0 nM 10.1128/aac.01462-06
Agrobacterium tumefaciens Agrobacterium tumefaciens MIC 250.0 ug.mL-1 10.1016/j.bmcl.2016.06.015
Aspergillus fumigatus Aspergillus fumigatus MIC nan None 10.1016/j.bmc.2009.07.039
Aspergillus niger Aspergillus niger IZ 0.0 mm 10.1007/s00044-011-9857-0
Bacillus Bacillus MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Bacillus Bacillus MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Bacillus Bacillus MIC90 1.0 ug.mL-1 10.1128/aac.00336-08
Bacillus anthracis Bacillus anthracis Activity nan None 10.1128/aac.00067-10
Bacillus anthracis Bacillus anthracis IZ nan None 10.1016/j.bmc.2008.05.032
Bacillus anthracis Bacillus anthracis MIC 0.125 ug.mL-1 10.1016/j.bmc.2007.08.035
Bacillus anthracis Bacillus anthracis MIC 0.25 ug.mL-1 10.1021/acs.jnatprod.0c01309
Bacillus anthracis Bacillus anthracis MIC 1.0 ug.mL-1 10.1128/aac.00737-08
Bacillus anthracis Bacillus anthracis MIC 2.0 ug.mL-1 10.1128/aac.00737-08
Bacillus anthracis Bacillus anthracis MIC 4.0 ug.mL-1 10.1128/aac.00737-08
Bacillus anthracis Bacillus anthracis MIC 8.0 ug.mL-1 10.1128/aac.00737-08
Bacillus anthracis Bacillus anthracis MIC 20.0 nM 10.1128/aac.00067-10
Bacillus anthracis Bacillus anthracis MIC 32.0 ug.mL-1 10.1128/aac.00737-08
Bacillus anthracis Bacillus anthracis MIC nan None 10.1016/j.bmc.2008.05.032
Bacillus cereus Bacillus cereus IZ 8.0 mm 10.1016/j.ejmech.2009.07.003
Bacillus cereus Bacillus cereus IZ 10.0 mm 10.1016/j.ejmech.2008.02.038
Bacillus cereus Bacillus cereus IZ 13.0 mm 10.1016/j.ejmech.2013.08.032
Bacillus cereus Bacillus cereus IZ 14.0 mm 10.1016/j.ejmech.2006.09.023
Bacillus cereus Bacillus cereus IZ 14.0 mm 10.1016/j.ejmech.2007.01.011
Bacillus cereus Bacillus cereus IZ nan None 10.1007/s00044-009-9177-9
Bacillus cereus Bacillus cereus MIC 0.008 ug.mL-1 10.1128/aac.00360-08
Bacillus cereus Bacillus cereus MIC 0.06 ug.mL-1 10.1128/aac.00360-08
Bacillus cereus Bacillus cereus MIC 0.097 ug.mL-1 10.1007/s00044-012-0294-5
Bacillus cereus Bacillus cereus MIC 0.12 ug.mL-1 10.1007/s00044-012-0028-8
Bacillus cereus Bacillus cereus MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.04.024
Bacillus cereus Bacillus cereus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Bacillus cereus Bacillus cereus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Bacillus cereus Bacillus cereus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Bacillus cereus Bacillus cereus MIC 7.81 ug.mL-1 10.1016/j.bmc.2019.115088
Bacillus cereus Bacillus cereus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2013.08.032
Bacillus cereus Bacillus cereus MIC 62.5 ug.mL-1 10.1016/j.bmcl.2013.09.082
Bacillus cereus Bacillus cereus MIC 22400.0 nM 10.1021/np050372r
Bacillus cereus Bacillus cereus Ratio 8.0 None 10.1128/aac.00360-08
Bacillus cereus Beta-lactamase 1 Kcat 2200.0 /s 10.1128/aac.00537-07
Bacillus cereus Beta-lactamase 1 Km 65000.0 nM 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat 97.0 /s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Kcat/Km 8.0 /uM/s 10.1128/aac.00537-07
Bacillus clausii Beta-lactamase Km 12000.0 nM 10.1128/aac.00537-07
Bacillus mycoides Bacillus mycoides MIC 1.56 ug.mL-1 10.1016/j.bmc.2009.07.039
Bacillus sp. Bacillus sp. MIC 3.125 ug.mL-1 10.1016/j.bmcl.2004.12.020
Bacillus spizizenii Bacillus spizizenii MIC 0.78 ug.mL-1 10.1016/j.bmc.2015.07.075
Bacillus spizizenii Bacillus spizizenii MIC 0.98 ug.mL-1 10.1016/j.ejmech.2020.112994
Bacillus spizizenii Bacillus spizizenii MIC 1.56 ug.mL-1 10.1016/j.bmcl.2013.05.006
Bacillus spizizenii Bacillus spizizenii MIC 1.56 ug.mL-1 10.1016/j.bmcl.2013.09.086
Bacillus spizizenii Bacillus spizizenii MIC 1.56 ug.mL-1 10.1016/j.ejmech.2013.11.020
Bacillus spizizenii Bacillus spizizenii MIC 1.56 ug.mL-1 10.1016/j.ejmech.2014.01.018
Bacillus spizizenii Bacillus spizizenii MIC 1.56 ug.mL-1 10.1016/j.ejmech.2020.112994
Bacillus spizizenii Bacillus spizizenii MIC 1.56 ug.mL-1 10.1039/C4MD00238E
Bacillus subtilis Bacillus subtilis DIZ nan None 10.1016/j.ejmech.2017.11.025
Bacillus subtilis Bacillus subtilis IC50 1.562 ug.mL-1 10.1016/j.ejmech.2009.04.014
Bacillus subtilis Bacillus subtilis IZ 4.6 mm 10.1016/j.ejmech.2012.03.004
Bacillus subtilis Bacillus subtilis IZ 7.0 mm 10.1007/s00044-010-9345-y
Bacillus subtilis Bacillus subtilis IZ 10.0 mm 10.1016/j.bmcl.2015.12.012
Bacillus subtilis Bacillus subtilis IZ 14.0 mm 10.1007/s00044-010-9345-y
Bacillus subtilis Bacillus subtilis IZ 14.0 mm 10.1007/s00044-010-9440-0
Bacillus subtilis Bacillus subtilis IZ 18.0 mm 10.1016/j.bmcl.2015.12.012
Bacillus subtilis Bacillus subtilis IZ 21.0 mm 10.1007/s00044-010-9530-z
Bacillus subtilis Bacillus subtilis IZ 22.0 mm 10.1016/j.ejmech.2010.01.050
Bacillus subtilis Bacillus subtilis IZ 24.0 mm 10.1016/j.ejmech.2020.113034
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1007/s00044-010-9440-0
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1007/s00044-011-9944-2
Bacillus subtilis Bacillus subtilis IZ 25.0 mm 10.1248/cpb.57.685
Bacillus subtilis Bacillus subtilis IZ 26.0 mm 10.1007/s00044-011-9944-2
Bacillus subtilis Bacillus subtilis IZ 26.2 mm 10.1016/j.ejmech.2019.111744
Bacillus subtilis Bacillus subtilis IZ 27.0 mm 10.1007/s00044-010-9530-z
Bacillus subtilis Bacillus subtilis IZ 28.0 mm 10.1021/acs.jnatprod.9b00475
Bacillus subtilis Bacillus subtilis IZ 31.6 mm 10.1016/j.ejmech.2016.11.019
Bacillus subtilis Bacillus subtilis IZ 32.5 mm 10.1016/j.ejmech.2011.07.035
Bacillus subtilis Bacillus subtilis IZ 32.56 mm 10.1016/j.ejmech.2011.08.018
Bacillus subtilis Bacillus subtilis IZ 35.0 mm 10.1007/s00044-013-0568-6
Bacillus subtilis Bacillus subtilis MBC 6.25 ug ml-1 10.1248/cpb.57.685
Bacillus subtilis Bacillus subtilis MIC 0.03 ug.mL-1 10.1021/np020380x
Bacillus subtilis Bacillus subtilis MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.01.075
Bacillus subtilis Bacillus subtilis MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.05.061
Bacillus subtilis Bacillus subtilis MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.06.077
Bacillus subtilis Bacillus subtilis MIC 0.06 ug.mL-1 10.1021/np400759f
Bacillus subtilis Bacillus subtilis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2016.06.015
Bacillus subtilis Bacillus subtilis MIC 0.125 ug.mL-1 10.1021/np5000457
Bacillus subtilis Bacillus subtilis MIC 0.25 ug.mL-1 10.1007/s00044-013-0568-6
Bacillus subtilis Bacillus subtilis MIC 0.335 ug.mL-1 10.1016/j.bmc.2014.03.004
Bacillus subtilis Bacillus subtilis MIC 0.39 ug.mL-1 10.1016/j.bmc.2009.07.039
Bacillus subtilis Bacillus subtilis MIC 0.39 ug.mL-1 10.1016/j.ejmech.2020.112666
Bacillus subtilis Bacillus subtilis MIC 0.752 ug.mL-1 10.1016/j.bmc.2014.09.048
Bacillus subtilis Bacillus subtilis MIC 0.78 ug.mL-1 10.1016/j.ejmech.2007.11.026
Bacillus subtilis Bacillus subtilis MIC 0.78 ug.mL-1 10.1016/j.ejmech.2010.01.066
Bacillus subtilis Bacillus subtilis MIC 1.526 ug.mL-1 10.1007/s00044-012-0332-3
Bacillus subtilis Bacillus subtilis MIC 1.526 ug.mL-1 10.1016/j.ejmech.2009.09.027
Bacillus subtilis Bacillus subtilis MIC 1.526 ug.mL-1 10.1016/j.ejmech.2010.04.016
Bacillus subtilis Bacillus subtilis MIC 1.56 ug.mL-1 10.1016/j.bmc.2011.06.077
Bacillus subtilis Bacillus subtilis MIC 1.56 ug.mL-1 10.1016/j.ejmech.2016.02.030
Bacillus subtilis Bacillus subtilis MIC 1.56 ug.mL-1 10.1248/cpb.57.685
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1007/s00044-010-9367-5
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1007/s00044-012-0168-x
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1007/s00044-012-0408-0
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2004.12.020
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2005.09.009
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2009.09.111
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.01.032
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.05.105
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.10.003
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.12.024
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2011.05.036
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2011.08.075
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2017.06.004
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2008.01.013
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2008.04.019
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2009.07.002
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2010.07.036
Bacillus subtilis Bacillus subtilis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2013.07.013
Bacillus subtilis Bacillus subtilis MIC 1.6 ug.mL-1 10.1016/j.ejmech.2010.03.027
Bacillus subtilis Bacillus subtilis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Bacillus subtilis Bacillus subtilis MIC 3.12 ug.mL-1 10.1021/np0602057
Bacillus subtilis Bacillus subtilis MIC 6.3 ug.mL-1 10.1021/acs.jnatprod.7b00713
Bacillus subtilis Bacillus subtilis MIC 7.8 ug.mL-1 10.1016/j.ejmech.2007.05.013
Bacillus subtilis Bacillus subtilis MIC 8.0 ug.mL-1 10.1021/np020044g
Bacillus subtilis Bacillus subtilis MIC 12.5 ug.mL-1 10.1007/s00044-011-9573-9
Bacillus subtilis Bacillus subtilis MIC 15.63 ug.mL-1 10.1016/j.bmcl.2013.09.082
Bacillus subtilis Bacillus subtilis MIC 25.0 ug.mL-1 10.1007/s00044-004-0035-5
Bacillus subtilis Bacillus subtilis MIC 25.0 ug.mL-1 10.1016/j.ejmech.2010.08.024
Bacillus subtilis Bacillus subtilis MIC 32.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Bacillus subtilis Bacillus subtilis MIC 32.0 ug.mL-1 10.1021/np010076o
Bacillus subtilis Bacillus subtilis MIC 32.0 ug.mL-1 10.1021/np030314a
Bacillus subtilis Bacillus subtilis MIC 50.0 ug.mL-1 10.1021/np50088a008
Bacillus subtilis Bacillus subtilis MIC 50.0 ug.mL-1 10.1128/aac.01436-08
Bacillus subtilis Bacillus subtilis MIC 1000.0 nM 10.1016/j.ejmech.2019.111636
Bacillus subtilis Bacillus subtilis MIC 1000.0 nM 10.1021/acs.jmedchem.1c00614
Bacillus subtilis Bacillus subtilis MIC 3500.0 nM 10.1021/acs.jnatprod.9b00475
Bacillus subtilis Bacillus subtilis MIC 4600.0 nM 10.1016/j.ejmech.2012.03.054
Bacillus subtilis Bacillus subtilis MIC 4600.0 nM 10.1016/j.ejmech.2012.09.003
Bacillus subtilis Bacillus subtilis MIC 25000.0 ug.mL-1 10.1016/j.ejmech.2010.01.050
Bacillus subtilis Bacillus subtilis MIC 383230.0 nM 10.1016/j.ejmech.2019.01.038
Bacillus subtilis Bacillus subtilis MIC nan None 10.1007/s00044-012-0408-0
Bacillus thuringiensis Bacillus thuringiensis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Bacillus thuringiensis Bacillus thuringiensis MIC 12.5 ug.mL-1 10.1128/aac.01436-08
Bacillus thuringiensis Bacillus thuringiensis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2016.06.015
Bacillus thuringiensis Bacillus thuringiensis MIC 128.0 ug.mL-1 10.1021/np5000457
Bacteria Bacterial 70S ribosome Ka 2.05 10^1/Ms 10.1016/j.bmc.2021.116138
Bacteria Bacterial 70S ribosome Ka 2.16 1/Ms 10.1016/j.ejmech.2022.114341
Bacteria Bacterial 70S ribosome Kd 2.63 10^-1M 10.1016/j.ejmech.2022.114341
Bacteria Bacterial 70S ribosome Kd 5.2 10^-1/s 10.1016/j.bmc.2021.116138
Bacteria Bacterial 70S ribosome Kd 5.69 10^-1/s 10.1016/j.ejmech.2022.114341
Bacteria Bacterial 70S ribosome Kdiss 2.54 10^-1M 10.1016/j.bmc.2021.116138
Bacteroides caccae Bacteroides caccae Activity 0.0 % 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae Activity 100.0 % 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC50 128.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides caccae Bacteroides caccae MIC90 128.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Activity 0.0 % 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis Activity 100.0 % 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Bacteroides fragilis Bacteroides fragilis MIC 4.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC50 16.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides fragilis Bacteroides fragilis MIC90 128.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 0.0 % 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity 100.0 % 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC 16.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 16.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 128.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis Activity 0.0 % 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis Activity 100.0 % 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC 2.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC50 128.0 ug.mL-1 10.1128/aac.00355-08
Bacteroides uniformis Bacteroides uniformis MIC90 128.0 ug.mL-1 10.1128/aac.00355-08
Bifidobacterium bifidum Bifidobacterium bifidum MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 1.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium bifidum Bifidobacterium bifidum MIC 3.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium breve Bifidobacterium breve MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium breve Bifidobacterium breve MIC 1.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium longum Bifidobacterium longum MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium longum Bifidobacterium longum MIC 3.9 ug.mL-1 10.1128/aac.00261-06
Bifidobacterium thermophilum Bifidobacterium thermophilum MIC 0.98 ug.mL-1 10.1128/aac.00261-06
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Brachyspira pilosicoli Class D beta-lactamase Activity 25.5 % 10.1128/aac.00684-07
Brachyspira pilosicoli Class D beta-lactamase Kcat 4.9 /s 10.1128/aac.00684-07
Brachyspira pilosicoli Class D beta-lactamase Kcat/Km 2.5 10'5/M/s 10.1128/aac.00684-07
Brachyspira pilosicoli Class D beta-lactamase Km 19000.0 nM 10.1128/aac.00684-07
Burkholderia cenocepacia PenB class A beta-lactamase Kcat 130.0 /s 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Kcat/Km 5200.0 /uM/s 10.1128/aac.00946-08
Burkholderia cenocepacia PenB class A beta-lactamase Km 25000.0 nM 10.1128/aac.00946-08
Campylobacter coli Campylobacter coli MIC 8.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC50 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter coli Campylobacter coli MIC90 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 2.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 4.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 8.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 16.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 128.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC 256.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC50 64.0 ug.mL-1 10.1128/aac.01655-08
Campylobacter jejuni Campylobacter jejuni MIC90 256.0 ug.mL-1 10.1128/aac.01655-08
Candida albicans Candida albicans DIZ nan None 10.1016/j.ejmech.2017.11.025
Candida albicans Candida albicans IZ nan None 10.1016/j.bmcl.2006.05.021
Candida albicans Candida albicans MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Candida albicans Candida albicans MIC 64.0 ug.mL-1 10.1021/np400759f
Candida albicans Candida albicans MIC 128.0 ug.mL-1 10.1021/np010076o
Candida albicans Candida albicans MIC 128.0 ug.mL-1 10.1021/np030314a
Candida albicans Candida albicans MIC nan None 10.1016/j.bmc.2009.07.039
Candida albicans Candida albicans MIC nan None 10.1016/j.bmcl.2011.06.081
Candida albicans Candida albicans MIC nan None 10.1016/j.ejmech.2011.07.042
Candida parapsilosis Candida parapsilosis DIZ nan None 10.1016/j.ejmech.2017.11.025
Candida tropicalis Candida tropicalis DIZ nan None 10.1016/j.ejmech.2017.11.025
Carnobacterium divergens Carnobacterium divergens MIC 3.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC 6.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC 12.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC 96.0 ug.mL-1 10.1128/aac.01145-07
Carnobacterium divergens Carnobacterium divergens MIC nan None 10.1128/aac.01145-07
Caulobacter vibrioides Metallo-beta-lactamase Kcat/Km 4.5 10'5/M/s 10.1128/aac.01062-07
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chlamydia trachomatis Chlamydia trachomatis Inhibition nan % 10.1021/acs.jmedchem.0c00371
[Chlorella] fusca [Chlorella] fusca IZ 0.0 mm 10.1016/j.fitote.2011.12.017
[Chlorella] fusca [Chlorella] fusca IZ nan None 10.1021/np300475d
Chromobacterium violaceum Chromobacterium violaceum IZ 25.0 mm 10.1248/cpb.57.685
Chromobacterium violaceum Chromobacterium violaceum MBC 12.5 ug ml-1 10.1248/cpb.57.685
Chromobacterium violaceum Chromobacterium violaceum MIC 1.56 ug.mL-1 10.1016/j.ejmech.2016.02.030
Chromobacterium violaceum Chromobacterium violaceum MIC 12.5 ug.mL-1 10.1016/j.bmcl.2005.09.009
Chromobacterium violaceum Chromobacterium violaceum MIC 12.5 ug.mL-1 10.1248/cpb.57.685
Chryseobacterium indologenes IND-like metallo-beta-lactamase Kcat/Km 8.4 10'5/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-2 Kcat/Km 4.6 10'6/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Kcat 305.0 /s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Kcat/Km 1.5 10'7/M/s 10.1128/aac.01607-08
Chryseobacterium indologenes Metallo-beta-lactamase IND-6 Km 20000.0 nM 10.1128/aac.01607-08
Citrobacter freundii PER-2 beta-lactamase Activity 18.0 % 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Kcat 2.0 /s 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Kcat/Km 0.12 /uM/s 10.1128/aac.01395-06
Citrobacter freundii PER-2 beta-lactamase Km 16000.0 nM 10.1128/aac.01395-06
Citrobacter gillenii Gil1 Kcat 286.0 /s 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Kcat/Km 5600.0 /mM/s 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Km 51000.0 nM 10.1128/aac.01152-06
Citrobacter gillenii Gil1 Ratio 100.0 None 10.1128/aac.01152-06
Clostridium paraputrificum Clostridium paraputrificum MIC 0.12 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Clostridium paraputrificum Clostridium paraputrificum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.01.075
Clostridium perfringens Clostridium perfringens MIC 0.12 ug.mL-1 10.1016/j.bmcl.2009.05.061
Clostridium perfringens Clostridium perfringens MIC 0.12 ug.mL-1 10.1016/j.bmcl.2009.06.077
Clostridium perfringens Clostridium perfringens MIC 0.12 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Clostridium perfringens Clostridium perfringens MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC 0.12 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Clostridium septicum Clostridium septicum MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC 0.12 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Clostridium tertium Clostridium tertium MIC90 4.0 ug.mL-1 10.1128/aac.00355-08
Corynebacterium ammoniagenes Corynebacterium ammoniagenes MIC 0.39 ug.mL-1 10.1021/np50088a008
Cutibacterium acnes Cutibacterium acnes MIC 0.012 ug.mL-1 10.1021/np50088a008
Elizabethkingia meningoseptica GOB-1 metallo-beta-lactamase Kcat/Km 1.9 10'7/M/s 10.1128/aac.01062-07
Enterobacter cloacae Beta-lactamase Activity 1.3 % 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Activity 1.3 % 10.1128/aac.01004-09
Enterobacter cloacae Beta-lactamase Activity 1.7 % 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Activity 9.4 % 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Activity 89.0 % 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Activity 89.0 % 10.1128/aac.01004-09
Enterobacter cloacae Beta-lactamase Activity 99.0 % 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Activity 520.0 % 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Kcat 32.0 /s 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Kcat 32.0 /s 10.1128/aac.01004-09
Enterobacter cloacae Beta-lactamase Kcat 53.0 /s 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Kcat 65.0 /s 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Kcat/Km 6.8 /s/microM 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Kcat/Km 6.8 /s/microM 10.1128/aac.01004-09
Enterobacter cloacae Beta-lactamase Kcat/Km 7.8 /s/microM 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Kcat/Km 8.8 /s/microM 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Km 4700.0 nM 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Km 4700.0 nM 10.1128/aac.01004-09
Enterobacter cloacae Beta-lactamase Km 6000.0 nM 10.1128/aac.00218-07
Enterobacter cloacae Beta-lactamase Km 8300.0 nM 10.1128/aac.00218-07
Enterobacter cloacae Enterobacter cloacae IZ nan None 10.1016/j.bmcl.2006.05.021
Enterobacter cloacae Enterobacter cloacae MIC 3.125 ug.mL-1 10.1016/j.bmcl.2009.09.111
Enterobacter cloacae Enterobacter cloacae MIC 3.125 ug.mL-1 10.1016/j.bmcl.2010.05.105
Enterobacter cloacae Enterobacter cloacae MIC 3.125 ug.mL-1 10.1016/j.ejmech.2008.04.019
Enterobacter cloacae Enterobacter cloacae MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Enterobacter cloacae Enterobacter cloacae MIC 100.0 ug.mL-1 10.1021/jm00346a024
Enterococcus faecalis Enterococcus faecalis Activity 0.0 % 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis Activity 100.0 % 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis IZ 20.0 mm 10.1016/j.bmcl.2015.02.044
Enterococcus faecalis Enterococcus faecalis IZ nan None 10.1016/j.bmcl.2006.05.021
Enterococcus faecalis Enterococcus faecalis MIC 0.5 ug.mL-1 10.1016/j.bmc.2019.02.024
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.12.054
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC 1.0 ug.mL-1 10.1128/aac.00859-08
Enterococcus faecalis Enterococcus faecalis MIC 1.56 ug.mL-1 10.1021/jm00346a024
Enterococcus faecalis Enterococcus faecalis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2009.09.111
Enterococcus faecalis Enterococcus faecalis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.05.105
Enterococcus faecalis Enterococcus faecalis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2008.04.019
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.07.042
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1128/aac.00576-06
Enterococcus faecalis Enterococcus faecalis MIC 2.0 ug.mL-1 10.1128/aac.00859-08
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1021/np400759f
Enterococcus faecalis Enterococcus faecalis MIC 4.0 ug.mL-1 10.1128/aac.00859-08
Enterococcus faecalis Enterococcus faecalis MIC 12.5 ug.mL-1 10.1007/s00044-004-0035-5
Enterococcus faecalis Enterococcus faecalis MIC 14.0 ug.mL-1 10.1021/np9805084
Enterococcus faecalis Enterococcus faecalis MIC 4000.0 nM 10.1021/acs.jmedchem.1c00614
Enterococcus faecalis Enterococcus faecalis MIC 11900.0 nM 10.1016/j.bmcl.2011.06.081
Enterococcus faecalis Enterococcus faecalis MIC 383230.0 nM 10.1016/j.ejmech.2019.01.038
Enterococcus faecalis Enterococcus faecalis MIC nan None 10.1128/aac.00859-08
Enterococcus faecalis Enterococcus faecalis MIC50 2.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC50 2.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecalis Enterococcus faecalis MIC90 4.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecalis Enterococcus faecalis MIC90 4.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecium Enterococcus faecium Activity 0.0 % 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium Activity 100.0 % 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium Inhibition nan % 10.1128/aac.00983-09
Enterococcus faecium Enterococcus faecium MIC 0.25 ug.mL-1 10.1016/j.bmc.2019.02.024
Enterococcus faecium Enterococcus faecium MIC 0.4 ug.mL-1 10.1021/jm00142a024
Enterococcus faecium Enterococcus faecium MIC 4.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecium Enterococcus faecium MIC 5.0 ug.mL-1 10.1128/aac.00983-09
Enterococcus faecium Enterococcus faecium MIC 16.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1021/np010076o
Enterococcus faecium Enterococcus faecium MIC 32.0 ug.mL-1 10.1021/np030314a
Enterococcus faecium Enterococcus faecium MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Enterococcus faecium Enterococcus faecium MIC 70.0 ug.mL-1 10.1128/aac.00983-09
Enterococcus faecium Enterococcus faecium MIC 128.0 ug.mL-1 10.1021/np020044g
Enterococcus faecium Enterococcus faecium MIC 128.0 ug.mL-1 10.1128/aac.00576-06
Enterococcus faecium Enterococcus faecium MIC 256.0 ug.mL-1 10.1128/aac.00576-06
Enterococcus faecium Enterococcus faecium MIC nan None 10.1128/aac.00859-08
Enterococcus faecium Enterococcus faecium MIC50 4.0 ug.mL-1 10.1128/aac.00336-08
Enterococcus faecium Enterococcus faecium MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus faecium Enterococcus faecium MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Enterococcus sp. Enterococcus sp. MIC 7810.0 nM 10.1016/j.bmc.2014.05.064
Enterococcus sp. Enterococcus sp. MIC 7810.0 nM 10.1016/j.bmc.2014.12.019
Enterococcus sp. Enterococcus sp. MIC 7810.0 nM 10.1016/j.bmc.2015.10.029
Enterococcus sp. Enterococcus sp. MIC 7810.0 nM 10.1016/j.bmc.2016.02.004
Enterococcus sp. Enterococcus sp. MIC 15620.0 nM 10.1016/j.bmc.2014.05.064
Enterococcus sp. Enterococcus sp. MIC 15620.0 nM 10.1016/j.bmc.2014.12.019
Enterococcus sp. Enterococcus sp. MIC 15620.0 nM 10.1016/j.bmc.2015.10.029
Enterococcus sp. Enterococcus sp. MIC 15620.0 nM 10.1016/j.bmc.2016.02.004
Erysipelothrix rhusiopathiae Erysipelothrix rhusiopathiae MIC 13.0 ug.mL-1 10.1021/acs.jnatprod.8b00015
Escherichia coli Beta-lactamase Activity 3.1 % 10.1128/aac.01004-09
Escherichia coli Beta-lactamase Activity 420.0 % 10.1128/aac.01004-09
Escherichia coli Beta-lactamase Kcat 22.0 /s 10.1128/aac.01004-09
Escherichia coli Beta-lactamase Kcat/Km 10.0 /s/microM 10.1128/aac.01004-09
Escherichia coli Beta-lactamase Km 2200.0 nM 10.1128/aac.01004-09
Escherichia coli Beta-lactamase ACC-4 Kcat 0.59 /s 10.1128/aac.00389-07
Escherichia coli Beta-lactamase ACC-4 Kcat/Km 0.16 /s/microM 10.1128/aac.00389-07
Escherichia coli Beta-lactamase ACC-4 Km 3800.0 nM 10.1128/aac.00389-07
Escherichia coli Beta-lactamase CTX-M Activity 25.0 % 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Activity 25.0 % 10.1128/aac.01004-09
Escherichia coli Beta-lactamase CTX-M Activity 110.0 % 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Activity 110.0 % 10.1128/aac.01004-09
Escherichia coli Beta-lactamase CTX-M Kcat 47.0 /s 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Kcat 47.0 /s 10.1128/aac.01004-09
Escherichia coli Beta-lactamase CTX-M Kcat/Km 5.4 /s/microM 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Kcat/Km 5.4 /s/microM 10.1128/aac.01004-09
Escherichia coli Beta-lactamase CTX-M Km 8700.0 nM 10.1128/aac.00218-07
Escherichia coli Beta-lactamase CTX-M Km 8700.0 nM 10.1128/aac.01004-09
Escherichia coli Beta-lactamase SHV-1 Kcat 1937.0 /s 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-1 Kcat/Km 84.2 /uM/s 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-1 Km 23000.0 nM 10.1128/aac.01442-09
Escherichia coli Beta-lactamase SHV-11 Kcat 40.0 /s 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Kcat/Km 2000.0 /uM/s 10.1128/aac.00387-08
Escherichia coli Beta-lactamase SHV-11 Km 20000.0 nM 10.1128/aac.00387-08
Escherichia coli Beta-lactamase TEM Activity 120.0 % 10.1128/aac.01004-09
Escherichia coli Beta-lactamase TEM Activity 122.0 % 10.1128/aac.00218-07
Escherichia coli Beta-lactamase TEM Activity 5600.0 % 10.1128/aac.00218-07
Escherichia coli Beta-lactamase TEM Activity 5600.0 % 10.1128/aac.01004-09
Escherichia coli Beta-lactamase TEM K cat 1284.0 1/S 10.1021/jm0493663
Escherichia coli Beta-lactamase TEM Kcat 1200.0 /s 10.1128/aac.00218-07
Escherichia coli Beta-lactamase TEM Kcat 1200.0 /s 10.1128/aac.01004-09
Escherichia coli Beta-lactamase TEM Kcat 1500.0 /s 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Kcat/Km 44.0 None 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Kcat/Km 100.0 /s/microM 10.1128/aac.00218-07
Escherichia coli Beta-lactamase TEM Kcat/Km 100.0 /s/microM 10.1128/aac.01004-09
Escherichia coli Beta-lactamase TEM Ki 20000.0 nM 10.1021/jm00397a018
Escherichia coli Beta-lactamase TEM Km 34.0 /s/microM 10.1128/aac.00614-07
Escherichia coli Beta-lactamase TEM Km 12000.0 nM 10.1128/aac.00218-07
Escherichia coli Beta-lactamase TEM Km 12000.0 nM 10.1128/aac.01004-09
Escherichia coli Beta-lactamase TEM Km 75000.0 nM 10.1021/jm0493663
Escherichia coli Beta-lactamase Toho-1 Kcat 65.0 /s 10.1128/aac.00098-10
Escherichia coli Beta-lactamase Toho-1 Kcat/Km 3.6 10'6/s/M 10.1128/aac.00098-10
Escherichia coli Beta-lactamase Toho-1 Km 18000.0 nM 10.1128/aac.00098-10
Escherichia coli BlaVIM-1 Kcat 29.0 /s 10.1128/aac.00017-09
Escherichia coli BlaVIM-1 Kcat 30.0 /s 10.1128/aac.00458-09
Escherichia coli BlaVIM-1 Kcat/Km 0.034 /s/microM 10.1128/aac.00017-09
Escherichia coli BlaVIM-1 Kcat/Km 0.05 /uM/s 10.1128/aac.00458-09
Escherichia coli BlaVIM-1 Km 850000.0 nM 10.1128/aac.00458-09
Escherichia coli Class A carbapenemase KPC-2 Activity 15.0 % 10.1128/aac.00218-07
Escherichia coli Class A carbapenemase KPC-2 Activity 260.0 % 10.1128/aac.00218-07
Escherichia coli Class A carbapenemase KPC-2 Kcat 60.0 /s 10.1128/aac.00218-07
Escherichia coli Class A carbapenemase KPC-2 Kcat/Km 2.0 /s/microM 10.1128/aac.00218-07
Escherichia coli Class A carbapenemase KPC-2 Km 30000.0 nM 10.1128/aac.00218-07
Escherichia coli CMT-type beta lactamase Kcat 18.5 /s 10.1128/aac.00614-07
Escherichia coli CMT-type beta lactamase Kcat/Km 0.49 None 10.1128/aac.00614-07
Escherichia coli CMT-type beta lactamase Km 38.1 /s/microM 10.1128/aac.00614-07
Escherichia coli Escherichia coli Activity 0.0 % 10.1128/aac.00375-07
Escherichia coli Escherichia coli Activity 22.0 % 10.1128/aac.00601-07
Escherichia coli Escherichia coli Activity 30.0 % 10.1128/aac.00601-07
Escherichia coli Escherichia coli Activity 31.0 % 10.1128/aac.00601-07
Escherichia coli Escherichia coli Activity 35.0 % 10.1128/aac.00601-07
Escherichia coli Escherichia coli Activity 55.0 % 10.1128/aac.00601-07
Escherichia coli Escherichia coli Activity 71.0 % 10.1128/aac.00601-07
Escherichia coli Escherichia coli Activity nan None 10.1021/acs.jmedchem.0c00040
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00014-10
Escherichia coli Escherichia coli Activity nan None 10.1128/aac.00601-07
Escherichia coli Escherichia coli DIZ nan None 10.1016/j.ejmech.2017.11.025
Escherichia coli Escherichia coli IC50 6.25 ug.mL-1 10.1016/j.ejmech.2009.04.014
Escherichia coli Escherichia coli IC50 631000.0 nM 10.1016/j.ejmech.2018.12.017
Escherichia coli Escherichia coli Inhibition nan % 10.1021/np200062x
Escherichia coli Escherichia coli Inhibition nan % 10.1128/aac.00014-10
Escherichia coli Escherichia coli IZ 0.0 mm 10.1016/j.ejmech.2008.02.027
Escherichia coli Escherichia coli IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Escherichia coli Escherichia coli IZ 7.0 mm 10.1007/s00044-010-9345-y
Escherichia coli Escherichia coli IZ 8.0 % 10.1007/s00044-010-9425-z
Escherichia coli Escherichia coli IZ 8.0 mm 10.1021/np200330c
Escherichia coli Escherichia coli IZ 8.6 mm 10.1016/j.ejmech.2012.03.004
Escherichia coli Escherichia coli IZ 12.0 % 10.1007/s00044-010-9425-z
Escherichia coli Escherichia coli IZ 12.0 mm 10.1016/j.ejmech.2013.08.032
Escherichia coli Escherichia coli IZ 14.0 mm 10.1007/s00044-010-9345-y
Escherichia coli Escherichia coli IZ 14.0 mm 10.1007/s00044-010-9440-0
Escherichia coli Escherichia coli IZ 14.0 mm 10.1016/j.fitote.2011.12.017
Escherichia coli Escherichia coli IZ 15.0 mm 10.1016/j.bmcl.2015.02.044
Escherichia coli Escherichia coli IZ 17.0 mm 10.1007/s00044-009-9177-9
Escherichia coli Escherichia coli IZ 17.0 mm 10.1007/s00044-010-9450-y
Escherichia coli Escherichia coli IZ 18.0 mm 10.1016/j.ejmech.2006.09.023
Escherichia coli Escherichia coli IZ 18.0 mm 10.1016/j.ejmech.2007.01.011
Escherichia coli Escherichia coli IZ 18.0 mm 10.1016/j.ejmech.2008.02.038
Escherichia coli Escherichia coli IZ 18.0 mm 10.1016/j.ejmech.2009.07.003
Escherichia coli Escherichia coli IZ 18.0 mm 10.1016/j.ejmech.2010.01.050
Escherichia coli Escherichia coli IZ 19.0 mm 10.1007/s00044-007-9024-9
Escherichia coli Escherichia coli IZ 19.0 mm 10.1007/s00044-009-9206-8
Escherichia coli Escherichia coli IZ 20.0 mm 10.1021/np300475d
Escherichia coli Escherichia coli IZ 22.0 mm 10.1007/s00044-011-9857-0
Escherichia coli Escherichia coli IZ 22.0 mm 10.1016/j.ejmech.2020.113034
Escherichia coli Escherichia coli IZ 23.0 mm 10.1016/j.bmcl.2006.05.021
Escherichia coli Escherichia coli IZ 24.0 mm 10.1007/s00044-011-9944-2
Escherichia coli Escherichia coli IZ 24.0 mm 10.1021/acs.jnatprod.9b00475
Escherichia coli Escherichia coli IZ 25.0 mm 10.1007/s00044-010-9440-0
Escherichia coli Escherichia coli IZ 25.0 mm 10.1007/s00044-010-9530-z
Escherichia coli Escherichia coli IZ 25.0 mm 10.1016/j.bmcl.2017.09.052
Escherichia coli Escherichia coli IZ 26.0 mm 10.1016/j.bmcl.2012.05.001
Escherichia coli Escherichia coli IZ 30.0 mm 10.1007/s00044-011-9944-2
Escherichia coli Escherichia coli IZ 30.0 mm 10.1007/s00044-013-0568-6
Escherichia coli Escherichia coli IZ 31.0 mm 10.1007/s00044-010-9530-z
Escherichia coli Escherichia coli IZ 31.0 mm 10.1007/s00044-011-9944-2
Escherichia coli Escherichia coli IZ 33.1 mm 10.1016/j.ejmech.2016.11.019
Escherichia coli Escherichia coli IZ 33.5 mm 10.1016/j.ejmech.2011.07.035
Escherichia coli Escherichia coli IZ 33.56 mm 10.1016/j.ejmech.2011.08.018
Escherichia coli Escherichia coli IZ 54.0 mm 10.1016/j.bmcl.2006.05.021
Escherichia coli Escherichia coli IZ nan None 10.1016/j.bmcl.2006.05.021
Escherichia coli Escherichia coli MIC 0.097 ug.mL-1 10.1007/s00044-012-0294-5
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1007/s00044-012-0028-8
Escherichia coli Escherichia coli MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.04.024
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1007/s00044-013-0568-6
Escherichia coli Escherichia coli MIC 0.5 ug.mL-1 10.1128/aac.00454-09
Escherichia coli Escherichia coli MIC 0.77 ug.mL-1 10.1016/j.bmcl.2017.09.052
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Escherichia coli Escherichia coli MIC 1.0 ug.mL-1 10.1021/np020380x
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1016/j.bmc.2007.08.035
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/np010076o
Escherichia coli Escherichia coli MIC 2.0 ug.mL-1 10.1021/np020044g
Escherichia coli Escherichia coli MIC 2.3 ug.mL-1 10.1021/jm980476h
Escherichia coli Escherichia coli MIC 2.5 ug.mL-1 10.1016/j.bmc.2011.01.051
Escherichia coli Escherichia coli MIC 2.87 ug.mL-1 10.1021/jm000213z
Escherichia coli Escherichia coli MIC 3.125 ug.mL-1 10.1016/j.bmcl.2010.05.105
Escherichia coli Escherichia coli MIC 3.125 ug.mL-1 10.1016/j.ejmech.2020.112666
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/j.bmc.2011.06.077
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/j.bmcl.2013.05.006
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/j.bmcl.2013.09.086
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/j.ejmech.2013.11.020
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/j.ejmech.2014.01.018
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1016/j.ejmech.2020.112994
Escherichia coli Escherichia coli MIC 3.13 ug.mL-1 10.1039/C4MD00238E
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1021/np030314a
Escherichia coli Escherichia coli MIC 4.0 ug.mL-1 10.1128/aac.01145-07
Escherichia coli Escherichia coli MIC 5.0 ug.mL-1 10.1128/aac.00454-09
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1007/s00044-012-0332-3
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1007/s00044-012-0408-0
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.bmc.2015.07.075
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.bmcl.2009.09.111
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.bmcl.2010.01.032
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.ejmech.2008.01.013
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.ejmech.2008.04.019
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.ejmech.2009.09.027
Escherichia coli Escherichia coli MIC 7.81 ug.mL-1 10.1016/j.ejmech.2010.04.016
Escherichia coli Escherichia coli MIC 7.82 ug.mL-1 10.1016/j.ejmech.2020.112994
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1016/j.ejmech.2012.03.008
Escherichia coli Escherichia coli MIC 8.0 ug.mL-1 10.1021/np400759f
Escherichia coli Escherichia coli MIC 12.0 ug.mL-1 10.1016/S0960-894X(01)80948-3
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1007/s00044-010-9367-5
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1007/s00044-011-9573-9
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1007/s00044-012-0168-x
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1016/j.bmcl.2010.10.003
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1016/j.bmcl.2011.05.036
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1016/j.bmcl.2011.08.075
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1016/j.bmcl.2017.06.004
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1016/j.ejmech.2009.07.002
Escherichia coli Escherichia coli MIC 12.5 ug.mL-1 10.1016/j.ejmech.2013.07.013
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1016/j.ejmech.2016.12.054
Escherichia coli Escherichia coli MIC 16.0 ug.mL-1 10.1021/acs.jnatprod.0c01309
Escherichia coli Escherichia coli MIC 20.0 ug.mL-1 10.1021/acs.jmedchem.7b00204
Escherichia coli Escherichia coli MIC 22.36 ug.mL-1 10.1016/j.bmc.2014.09.048
Escherichia coli Escherichia coli MIC 22.84 ug.mL-1 10.1016/j.bmc.2014.03.004
Escherichia coli Escherichia coli MIC 24.0 ug.mL-1 10.1128/aac.00684-07
Escherichia coli Escherichia coli MIC 25.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Escherichia coli Escherichia coli MIC 25.0 ug.mL-1 10.1021/jm00142a024
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1016/j.ejmech.2013.08.032
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/np010076o
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/np030314a
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1021/np400759f
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 32.0 ug.mL-1 10.1128/aac.01472-06
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1007/s00044-004-0035-5
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/j.ejmech.2007.05.013
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/j.ejmech.2010.03.027
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/j.ejmech.2010.08.024
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1016/S0960-894X(01)80948-3
Escherichia coli Escherichia coli MIC 50.0 ug.mL-1 10.1128/aac.00601-07
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.04.123
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.07.042
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1039/d2md00041e
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.00710-10
Escherichia coli Escherichia coli MIC 64.0 ug.mL-1 10.1128/aac.01472-06
Escherichia coli Escherichia coli MIC 100.0 ug.mL-1 10.1021/jm00346a024
Escherichia coli Escherichia coli MIC 125.0 ug.mL-1 10.1016/j.bmcl.2013.09.082
Escherichia coli Escherichia coli MIC 125.0 ug.mL-1 10.1128/aac.00601-07
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/np010076o
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1021/np5000457
Escherichia coli Escherichia coli MIC 128.0 ug.mL-1 10.1128/aac.01025-07
Escherichia coli Escherichia coli MIC 250.0 ug.mL-1 10.1128/aac.00601-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.00684-07
Escherichia coli Escherichia coli MIC 256.0 ug.mL-1 10.1128/aac.01145-07
Escherichia coli Escherichia coli MIC 560.0 ug.mL-1 10.1021/np9805084
Escherichia coli Escherichia coli MIC 2000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 8000.0 nM 10.1016/j.ejmech.2019.111636
Escherichia coli Escherichia coli MIC 25000.0 ug.mL-1 10.1016/j.ejmech.2010.01.050
Escherichia coli Escherichia coli MIC 27800.0 nM 10.1021/acs.jnatprod.9b00475
Escherichia coli Escherichia coli MIC 32000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 37400.0 nM 10.1016/j.ejmech.2012.03.054
Escherichia coli Escherichia coli MIC 37400.0 nM 10.1016/j.ejmech.2012.09.003
Escherichia coli Escherichia coli MIC 64000.0 nM 10.1016/j.ejmech.2019.111636
Escherichia coli Escherichia coli MIC 64000.0 nM 10.1021/acs.jmedchem.1c00614
Escherichia coli Escherichia coli MIC 100000.0 nM 10.1016/j.bmcl.2012.04.018
Escherichia coli Escherichia coli MIC 125000.0 nM 10.1016/j.bmc.2015.10.029
Escherichia coli Escherichia coli MIC 125000.0 nM 10.1016/j.bmc.2016.02.004
Escherichia coli Escherichia coli MIC 128000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC 383230.0 nM 10.1016/j.ejmech.2019.01.038
Escherichia coli Escherichia coli MIC 512000.0 ug.mL-1 10.1128/aac.00537-07
Escherichia coli Escherichia coli MIC nan None 10.1007/s00044-012-0408-0
Escherichia coli Escherichia coli MIC nan None 10.1016/j.bmc.2009.07.039
Escherichia coli Escherichia coli MIC nan None 10.1016/j.bmcl.2015.07.044
Escherichia coli Escherichia coli MIC nan None 10.1016/j.ejmech.2019.01.038
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01436-08
Escherichia coli Escherichia coli MIC nan None 10.1128/aac.01442-09
Escherichia coli Escherichia coli MIC50 2.0 ug.mL-1 10.1016/j.ejmech.2011.07.047
Escherichia coli Escherichia coli MIC50 2.7 ug.mL-1 10.1016/j.bmc.2011.05.042
Escherichia coli Escherichia coli MIC90 4000.0 nM 10.1039/C5MD00325C
Escherichia coli Escherichia coli MIC90 100000.0 nM 10.1016/j.bmcl.2013.03.053
Escherichia coli Escherichia coli MIC90 128000.0 nM 10.1039/C5MD00325C
Escherichia coli Escherichia coli MIC90 nan None 10.1039/C5MD00325C
Escherichia coli Escherichia coli Ratio 2.0 None 10.1016/j.ejmech.2012.03.008
Escherichia coli Metallo-beta-lactamase Kcat 55.8 /s 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase Kcat/Km 1.14 /s/microM 10.1128/aac.00017-09
Escherichia coli Metallo-beta-lactamase VIM-19 Kcat 1300.0 /s 10.1128/aac.00458-09
Escherichia coli Metallo-beta-lactamase VIM-19 Kcat/Km 5.0 /uM/s 10.1128/aac.00458-09
Escherichia coli Metallo-beta-lactamase VIM-19 Km 300000.0 nM 10.1128/aac.00458-09
Finegoldia magna Finegoldia magna MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC50 0.03 ug.mL-1 10.1128/aac.00355-08
Finegoldia magna Finegoldia magna MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Flavobacterium meningosepticum Carbapenem-hydrolyzing beta-lactamase BlaB-1 Kcat/Km 2.7 10'7/M/s 10.1128/aac.01607-08
Fluoribacter gormanii FEZ-1 protein Kcat/Km 1.1 10'5/M/s 10.1128/aac.01062-07
Fusobacterium mortiferum Fusobacterium mortiferum Activity 11.0 % 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum Activity 85.0 % 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Fusobacterium mortiferum Fusobacterium mortiferum MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum Activity 11.0 % 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum Activity 85.0 % 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Fusobacterium necrophorum Fusobacterium necrophorum MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity 11.0 % 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum Activity 85.0 % 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum GI nan None 10.1021/np2004775
Fusobacterium nucleatum Fusobacterium nucleatum MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Fusobacterium nucleatum Fusobacterium nucleatum MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium Activity 11.0 % 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium Activity 85.0 % 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC50 0.25 ug.mL-1 10.1128/aac.00355-08
Fusobacterium varium Fusobacterium varium MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Haemophilus influenzae Haemophilus influenzae Activity nan None 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 0.06 ug.mL-1 10.1021/np400759f
Haemophilus influenzae Haemophilus influenzae MIC 0.25 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC 0.5 ug.mL-1 10.1128/aac.01489-09
Haemophilus influenzae Haemophilus influenzae MIC 16.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Haemophilus influenzae Haemophilus influenzae MIC 256.0 ug.mL-1 10.1128/aac.01489-09
Haemophilus influenzae Haemophilus influenzae MIC50 0.5 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC50 1.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC50 32.0 ug.mL-1 10.1021/jm1014023
Haemophilus influenzae Haemophilus influenzae MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC90 4.0 ug.mL-1 10.1128/aac.00418-09
Haemophilus influenzae Haemophilus influenzae MIC90 32.0 ug.mL-1 10.1021/jm1014023
Homo sapiens 5637 Activity nan None 10.1128/aac.00014-10
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile salt export pump AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 10000.0 nM 10.1124/dmd.112.047068
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Caco-2 logPapp -6.11 None 10.1016/j.bmc.2011.03.011
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity 76.0 % 10.1021/jm7015683
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens Guanine nucleotide-binding protein G(s), subunit alpha Potency 44668.4 nM None
Homo sapiens HeLa Activity nan None 10.1128/aac.00729-05
Homo sapiens HeLa GI50 nan None 10.1016/j.bmcl.2011.06.081
Homo sapiens HepG2 IC50 10000000.0 nM 10.1016/j.bmc.2014.05.064
Homo sapiens HepG2 IC50 10000000.0 nM 10.1016/j.bmc.2014.12.019
Homo sapiens HepG2 IC50 nan None 10.1016/j.bmc.2014.12.019
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 6800.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -44.78 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -1.92 % 10.6019/CHEMBL4808148
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens Activity 0.3 % 10.1016/j.ejmech.2009.11.034
Homo sapiens Homo sapiens Activity 50.6 umol/Kg 10.1128/aac.01506-06
Homo sapiens Homo sapiens Activity 70.6 umol/Kg 10.1128/aac.01506-06
Homo sapiens Homo sapiens AUC 161183.33 ng.hr.mL-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens AUC 389336.67 ng.hr.mL-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens AUC nan None 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL 0.103 L/hr 10.1128/aac.00318-07
Homo sapiens Homo sapiens CL 0.774 L/hr 10.1128/aac.00318-07
Homo sapiens Homo sapiens CL 1.2 mL.min-1.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL 1.5 mL.min-1.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL 2.0 mL.min-1.kg-1 10.1128/aac.00318-07
Homo sapiens Homo sapiens CL 6.9 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL nan None 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL_renal 0.27 ml/min 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL_renal 0.31 ml/min 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL_renal 0.38 mL.min-1.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL_renal 0.46 mL.min-1.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens CL_renal 5.0 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens Cmax 65789.47 nM 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmax 134569.38 nM 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmax 176136.36 nM 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmax 435107.66 nM 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmin 2.3 ug ml-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmin 3.4 ug ml-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmin 7.1 ug ml-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Cmin nan None 10.1128/aac.01506-06
Homo sapiens Homo sapiens Concentration 0.32 ug ml-1 10.1021/jm00128a019
Homo sapiens Homo sapiens Concentration 7.5 ug ml-1 10.1021/jm00128a019
Homo sapiens Homo sapiens Creatinine_CL 0.26 ml/min 10.1128/aac.01506-06
Homo sapiens Homo sapiens Creatinine_CL 0.3 ml/min.kg 10.1128/aac.01506-06
Homo sapiens Homo sapiens Creatinine_CL 0.53 ml/min 10.1128/aac.01506-06
Homo sapiens Homo sapiens Creatinine_CL 0.57 ml/min.kg 10.1128/aac.01506-06
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 3.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 22.5 % 10.1016/j.bmc.2007.08.060
Homo sapiens Homo sapiens T1/2 0.5 hr 10.1128/aac.01506-06
Homo sapiens Homo sapiens T1/2 3.4 hr 10.1128/aac.01506-06
Homo sapiens Homo sapiens T1/2 3.8 hr 10.1128/aac.00318-07
Homo sapiens Homo sapiens T1/2 3.8 hr 10.1128/aac.01506-06
Homo sapiens Homo sapiens T1/2 3.9 hr 10.1128/aac.00318-07
Homo sapiens Homo sapiens T1/2 4.6 hr 10.1128/aac.01506-06
Homo sapiens Homo sapiens Vc 0.359 l 10.1128/aac.00318-07
Homo sapiens Homo sapiens Vd 0.45 L.kg-1 10.1128/aac.00318-07
Homo sapiens Homo sapiens Vd 0.61 L.kg-1 10.1128/aac.00318-07
Homo sapiens Homo sapiens Vdss 0.41 L.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Vdss 0.45 L.kg-1 10.1016/j.ejmech.2009.06.004
Homo sapiens Homo sapiens Vdss 0.5 L.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Vdss 0.51 L.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Vdss 0.54 l 10.1128/aac.00318-07
Homo sapiens Homo sapiens Vdss 0.64 L.kg-1 10.1128/aac.01506-06
Homo sapiens Homo sapiens Vp/F 0.152 l 10.1128/aac.00318-07
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Kappa opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens MG-63 Activity nan None 10.1128/aac.00729-05
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Oligopeptide transporter small intestine isoform Activity nan None 10.2133/dmpk.17.253
Homo sapiens Oligopeptide transporter small intestine isoform Ki 30000000.0 nM 10.1016/j.ejpb.2004.07.008
Homo sapiens Oligopeptide transporter small intestine isoform Ki 30000000.0 nM 10.1021/jm048982w
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Solute carrier family 15 member 2 Ki 10964781.96 nM 10.1016/j.bmc.2011.06.027
Homo sapiens Solute carrier family 15 member 2 Ki 11000000.0 nM 10.1016/j.bmc.2011.06.027
Homo sapiens Solute carrier family 22 member 11 Activity 79.7 % 10.1124/jpet.102.034330
Homo sapiens Solute carrier family 22 member 11 Activity nan None 10.1016/s0167-4889(02)00187-8
Homo sapiens Solute carrier family 22 member 4 Activity nan None None
Homo sapiens Solute carrier family 22 member 5 Activity nan None 10.1074/jbc.275.3.1699
Homo sapiens Solute carrier family 22 member 6 Activity nan None 10.1016/s0024-3205(01)01296-6
Homo sapiens Solute carrier family 22 member 6 Activity nan None 10.1124/jpet.102.034330
Homo sapiens Solute carrier family 22 member 6 Activity nan None 10.1152/ajprenal.1999.276.1.f122
Homo sapiens Solute carrier family 22 member 6 Activity nan None 10.1152/ajprenal.1999.276.2.f295
Homo sapiens Solute carrier family 22 member 8 Activity nan None 10.1016/s0024-3205(01)01296-6
Homo sapiens Solute carrier family 22 member 8 Activity nan None 10.1124/mol.59.5.1277
Homo sapiens Solute carrier family 22 member 8 Inhibition nan % 10.1124/dmd.112.049569
Homo sapiens Solute carrier family 22 member 8 Ki 97600.0 nM 10.1124/jpet.102.034330
Homo sapiens Solute carrier organic anion transporter family member 1B1 Activity nan None 10.1006/bbrc.2000.2922
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 8.8 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 40.9 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Activity nan None 10.1006/bbrc.2000.2922
Homo sapiens Solute carrier organic anion transporter family member 2B1 Inhibition 7.6 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 3A1 Activity nan None 10.1006/bbrc.2000.2922
Homo sapiens Solute carrier organic anion transporter family member 4A1 Activity nan None 10.1006/bbrc.2000.2922
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Type-1 angiotensin II receptor AC50 100000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Klebsiella aerogenes Klebsiella aerogenes IZ 30.0 mm 10.1248/cpb.57.685
Klebsiella aerogenes Klebsiella aerogenes MBC 12.5 ug ml-1 10.1248/cpb.57.685
Klebsiella aerogenes Klebsiella aerogenes MIC 1.56 ug.mL-1 10.1016/j.ejmech.2016.02.030
Klebsiella aerogenes Klebsiella aerogenes MIC 6.25 ug.mL-1 10.1016/j.bmcl.2004.12.020
Klebsiella aerogenes Klebsiella aerogenes MIC 6.25 ug.mL-1 10.1016/j.bmcl.2005.09.009
Klebsiella aerogenes Klebsiella aerogenes MIC 6.25 ug.mL-1 10.1248/cpb.57.685
Klebsiella aerogenes Klebsiella aerogenes MIC 64.0 ug.mL-1 10.1128/aac.00710-10
Klebsiella oxytoca Beta-lactamase Activity 160.0 % 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Activity 400.0 % 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Kcat 1100.0 /s 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Kcat/Km 28.0 /s/microM 10.1128/aac.00218-07
Klebsiella oxytoca Beta-lactamase Km 40000.0 nM 10.1128/aac.00218-07
Klebsiella oxytoca Klebsiella oxytoca IZ 8.0 mm 10.1016/j.ejmech.2017.11.025
Klebsiella pneumoniae Beta-lactamase AH27 CTX-M-15 Kcat 47.0 /s 10.1128/aac.00461-09
Klebsiella pneumoniae Beta-lactamase AH27 CTX-M-15 Km 8700.0 nM 10.1128/aac.00461-09
Klebsiella pneumoniae Beta-lactamase AH27 CTX-M-15 Ratio 5.4 None 10.1128/aac.00461-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Kcat 11.0 /s 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Kcat/Km 0.68 /s/microM 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase NDM-1 Km 16000.0 nM 10.1128/aac.00774-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Activity 260.0 % 10.1128/aac.00218-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Activity 270.0 % 10.1128/aac.01004-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Activity 2600.0 % 10.1128/aac.00218-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Activity 2700.0 % 10.1128/aac.01004-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 1100.0 /s 10.1128/aac.01004-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 1300.0 /s 10.1128/aac.00218-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 1937.0 /s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat 1937.0 /s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km 69.0 /s/microM 10.1128/aac.01004-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km 81.0 /s/microM 10.1128/aac.00218-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km 84.2 /uM/s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Kcat/Km 84.3 /uM/s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 16000.0 nM 10.1128/aac.00218-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 16000.0 nM 10.1128/aac.01004-09
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 23000.0 nM 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-1 Km 23000.0 nM 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Kcat 23.0 /s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Kcat/Km 5.3 /uM/s 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-55 Km 5000.0 nM 10.1128/aac.01525-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Kcat 5438.0 /s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Kcat/Km 286.2 /uM/s 10.1128/aac.01381-07
Klebsiella pneumoniae Beta-lactamase SHV-72 Km 19000.0 nM 10.1128/aac.01381-07
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Activity 15.0 % 10.1128/aac.01004-09
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Activity 260.0 % 10.1128/aac.01004-09
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat 60.0 /s 10.1128/aac.01004-09
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Kcat/Km 2.0 /s/microM 10.1128/aac.01004-09
Klebsiella pneumoniae Carbepenem-hydrolyzing beta-lactamase KPC Km 30000.0 nM 10.1128/aac.01004-09
Klebsiella pneumoniae Class C beta-lactamase CMY-36 Kcat 9.1 /s 10.1128/aac.01284-08
Klebsiella pneumoniae Class C beta-lactamase CMY-36 Kcat/Km 30.3 /uM/s 10.1128/aac.01284-08
Klebsiella pneumoniae Class C beta-lactamase CMY-36 Km 300.0 nM 10.1128/aac.01284-08
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Kcat 58.0 /s 10.1128/aac.00461-09
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Km 4900.0 nM 10.1128/aac.00461-09
Klebsiella pneumoniae Extended spectrum beta-lactamase CTX-M-71 Ratio 11.8 None 10.1128/aac.00461-09
Klebsiella pneumoniae Klebsiella pneumoniae Activity nan None 10.1128/aac.00710-10
Klebsiella pneumoniae Klebsiella pneumoniae IZ 0.0 mm 10.1016/j.ejmech.2008.02.027
Klebsiella pneumoniae Klebsiella pneumoniae IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Klebsiella pneumoniae Klebsiella pneumoniae IZ 12.0 mm 10.1016/j.bmcl.2006.05.021
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1016/j.ejmech.2006.09.023
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1016/j.ejmech.2007.01.011
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1016/j.ejmech.2008.02.038
Klebsiella pneumoniae Klebsiella pneumoniae IZ 18.0 mm 10.1016/j.ejmech.2009.07.003
Klebsiella pneumoniae Klebsiella pneumoniae IZ 21.0 mm 10.1016/j.ejmech.2010.01.050
Klebsiella pneumoniae Klebsiella pneumoniae IZ 25.0 mm 10.1021/acs.jnatprod.9b00475
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1007/s00044-010-9367-5
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1007/s00044-012-0168-x
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1016/j.bmcl.2010.10.003
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1016/j.bmcl.2011.05.036
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1016/j.bmcl.2011.08.075
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1016/j.bmcl.2017.06.004
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1016/j.ejmech.2013.07.013
Klebsiella pneumoniae Klebsiella pneumoniae MIC 12.5 ug.mL-1 10.1007/s00044-004-0035-5
Klebsiella pneumoniae Klebsiella pneumoniae MIC 12.5 ug.mL-1 10.1016/j.ejmech.2010.08.024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 25.0 ug.mL-1 10.1007/s00044-011-9573-9
Klebsiella pneumoniae Klebsiella pneumoniae MIC 25.0 ug.mL-1 10.1021/jm00346a024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1021/jm000213z
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1021/jm980476h
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128.0 ug.mL-1 10.1021/np010076o
Klebsiella pneumoniae Klebsiella pneumoniae MIC 25000.0 ug.mL-1 10.1016/j.ejmech.2010.01.050
Klebsiella pneumoniae Klebsiella pneumoniae MIC 27800.0 nM 10.1021/acs.jnatprod.9b00475
Klebsiella pneumoniae Klebsiella pneumoniae MIC 128000.0 nM 10.1016/j.ejmech.2019.111636
Klebsiella pneumoniae Klebsiella pneumoniae MIC 500000.0 nM 10.1016/j.bmc.2015.10.029
Klebsiella pneumoniae Klebsiella pneumoniae MIC 500000.0 nM 10.1016/j.bmc.2016.02.004
Klebsiella pneumoniae Klebsiella pneumoniae MIC 512000.0 nM 10.1021/acs.jmedchem.1c00614
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Kcat 56.0 /s 10.1128/aac.00774-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Kcat/Km 1.14 /s/microM 10.1128/aac.00774-09
Klebsiella pneumoniae Metallo-beta-lactamase VIM-2 Km 49000.0 nM 10.1128/aac.00774-09
Klebsiella pneumoniae OXA-48 Kcat 8000.0 /s 10.1021/acs.jmedchem.6b00660
Klebsiella pneumoniae OXA-48 Kcat/Km 1.1 10'7/M/s 10.1021/acs.jmedchem.6b00660
Klebsiella pneumoniae OXA-48 Km 700000.0 nM 10.1021/acs.jmedchem.6b00660
Lactococcus lactis Lactococcus lactis MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Lactococcus lactis Lactococcus lactis MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Lactococcus lactis Lactococcus lactis MIC90 1.0 ug.mL-1 10.1128/aac.00336-08
Legionella pneumophila Legionella pneumophila MIC nan None 10.1021/np100730b
Listeria monocytogenes Listeria monocytogenes Activity 100.0 % 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes FC 2.0 None 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes IZ 10.0 mm 10.1016/j.ejmech.2006.09.023
Listeria monocytogenes Listeria monocytogenes IZ 10.0 mm 10.1016/j.ejmech.2007.01.011
Listeria monocytogenes Listeria monocytogenes IZ 10.0 mm 10.1016/j.ejmech.2008.02.038
Listeria monocytogenes Listeria monocytogenes IZ 10.0 mm 10.1016/j.ejmech.2009.07.003
Listeria monocytogenes Listeria monocytogenes IZ 30.5 mm 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes IZ 34.7 mm 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC 0.36 ug.mL-1 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes MIC 0.72 ug.mL-1 10.1128/aac.00503-10
Listeria monocytogenes Listeria monocytogenes MIC50 0.25 ug.mL-1 10.1128/aac.00418-09
Listeria monocytogenes Listeria monocytogenes MIC90 0.25 ug.mL-1 10.1128/aac.00418-09
Lysinibacillus sphaericus Lysinibacillus sphaericus IZ 28.0 mm 10.1248/cpb.57.685
Lysinibacillus sphaericus Lysinibacillus sphaericus MBC 25.0 ug ml-1 10.1248/cpb.57.685
Lysinibacillus sphaericus Lysinibacillus sphaericus MIC 1.56 ug.mL-1 10.1016/j.ejmech.2016.02.030
Lysinibacillus sphaericus Lysinibacillus sphaericus MIC 3.12 ug.mL-1 10.1248/cpb.57.685
Lysinibacillus sphaericus Lysinibacillus sphaericus MIC 3.125 ug.mL-1 10.1016/j.bmcl.2005.09.009
Microbotryum violaceum Microbotryum violaceum IZ 0.0 mm 10.1016/j.fitote.2011.12.017
Microbotryum violaceum Microbotryum violaceum IZ 0.0 mm 10.1021/np100730b
Microbotryum violaceum Microbotryum violaceum IZ 14.0 mm 10.1016/j.bmcl.2012.05.001
Microbotryum violaceum Microbotryum violaceum IZ 14.0 mm 10.1021/np200330c
Microbotryum violaceum Microbotryum violaceum IZ nan None 10.1021/np300475d
Micrococcus Micrococcus MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Micrococcus Micrococcus MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Micrococcus Micrococcus MIC90 1.0 ug.mL-1 10.1128/aac.00336-08
Micrococcus luteus Micrococcus luteus IZ 8.0 mm 10.1016/j.ejmech.2008.02.038
Micrococcus luteus Micrococcus luteus IZ 9.0 mm 10.1007/s00044-009-9273-x
Micrococcus luteus Micrococcus luteus IZ 10.0 mm 10.1016/j.ejmech.2009.07.003
Micrococcus luteus Micrococcus luteus IZ 31.0 mm 10.1007/s00044-009-9206-8
Micrococcus luteus Micrococcus luteus IZ 36.0 mm 10.1016/j.ejmech.2006.09.023
Micrococcus luteus Micrococcus luteus IZ 36.0 mm 10.1016/j.ejmech.2007.01.011
Micrococcus luteus Micrococcus luteus MIC 25.0 ug.mL-1 10.1128/aac.01436-08
Moraxella catarrhalis Moraxella catarrhalis MIC 0.03 ug.mL-1 10.1128/aac.00400-09
Moraxella catarrhalis Moraxella catarrhalis MIC 0.25 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC50 4.0 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC50 8.0 ug.mL-1 10.1021/jm1014023
Moraxella catarrhalis Moraxella catarrhalis MIC50 8.0 ug.mL-1 10.1128/aac.00400-09
Moraxella catarrhalis Moraxella catarrhalis MIC90 8.0 ug.mL-1 10.1128/aac.00400-09
Moraxella catarrhalis Moraxella catarrhalis MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Moraxella catarrhalis Moraxella catarrhalis MIC90 32.0 ug.mL-1 10.1021/jm1014023
Morganella morganii Beta-lactamase Activity 26.0 % 10.1128/aac.00218-07
Morganella morganii Beta-lactamase Activity 860.0 % 10.1128/aac.00218-07
Morganella morganii Beta-lactamase Kcat 190.0 /s 10.1128/aac.00218-07
Morganella morganii Beta-lactamase Kcat/Km 24.0 /s/microM 10.1128/aac.00218-07
Morganella morganii Beta-lactamase Km 7900.0 nM 10.1128/aac.00218-07
Mucor hiemalis Mucor hiemalis MIC 100.0 ug.mL-1 10.1021/np0602057
Mus musculus J774.A1 Activity 90.0 % 10.1128/aac.00375-07
Mus musculus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus P-glycoprotein 3 Ratio 1.0 None 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Ratio 1.1 None 10.1021/jm021012t
Mus musculus Solute carrier family 22 member 6 Inhibition nan % 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 Drug uptake nan None 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 IC50 89400.0 nM 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 Inhibition nan % 10.1124/dmd.112.049569
Mus musculus Solute carrier family 22 member 8 Km 40000.0 nM 10.1124/jpet.103.063370
Mycobacterium Mycobacterium IZ nan None 10.1016/j.bmcl.2006.05.021
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC 500.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 15.0 mm 10.1016/j.ejmech.2006.09.023
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 15.0 mm 10.1016/j.ejmech.2007.01.011
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 15.0 mm 10.1016/j.ejmech.2008.02.038
Mycolicibacterium smegmatis Mycolicibacterium smegmatis IZ 15.0 mm 10.1016/j.ejmech.2009.07.003
Naganishia albida Naganishia albida MIC nan None 10.1016/j.bmc.2009.07.039
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 0.0 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 3.9 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 5.1 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 6.7 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 7.9 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 8.0 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 9.2 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 9.3 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 9.7 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 10.7 % 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 11.3 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 12.1 % 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 15.4 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 16.7 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 17.3 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 22.9 % 10.1128/aac.00235-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 28.6 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 33.3 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 39.9 % 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 45.7 % 10.1128/aac.00235-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 47.1 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 49.0 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 50.0 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 58.9 % 10.1128/aac.00482-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 60.0 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 60.1 % 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 62.2 % 10.1128/aac.00482-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 71.0 % 10.1128/aac.00482-10
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 71.4 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 79.5 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 82.3 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 82.8 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 83.3 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 90.7 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae Activity 100.0 % 10.1128/aac.01420-07
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.008 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.011 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.012 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.016 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.017 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.031 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.037 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.059 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.06 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.064 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.067 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.07 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.081 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.133 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.155 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.156 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.5 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 0.63 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.0 ug.mL-1 10.1128/aac.00020-08
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.0 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.0 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 1.5 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 2.0 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 2.0 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 3.0 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 6.0 ug.mL-1 10.1128/aac.01604-06
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 16.0 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 32.0 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC 64.0 ug.mL-1 10.1128/aac.00245-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC50 0.25 ug.mL-1 10.1128/aac.00788-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC50 1.0 ug.mL-1 10.1128/aac.00235-10
Neisseria gonorrhoeae Neisseria gonorrhoeae MIC90 2.0 ug.mL-1 10.1128/aac.00788-10
Neisseria meningitidis Neisseria meningitidis Activity 0.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis Activity 0.0 % 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis Activity 2.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis Activity 50.0 % 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis Activity 84.5 % 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis Activity 98.0 % 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC 0.004 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.006 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC 0.008 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.015 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.015 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC 0.023 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.032 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.047 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis MIC 0.064 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.064 ug.mL-1 10.1128/aac.00914-07
Neisseria meningitidis Neisseria meningitidis MIC 0.094 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.094 ug.mL-1 10.1128/aac.00914-07
Neisseria meningitidis Neisseria meningitidis MIC 0.125 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC 0.19 ug.mL-1 10.1128/aac.00412-07
Neisseria meningitidis Neisseria meningitidis MIC50 0.03 ug.mL-1 10.1128/aac.01812-09
Neisseria meningitidis Neisseria meningitidis MIC50 0.047 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis MIC90 0.094 ug.mL-1 10.1128/aac.00994-08
Neisseria meningitidis Neisseria meningitidis MIC90 0.12 ug.mL-1 10.1128/aac.00418-09
Neisseria meningitidis Neisseria meningitidis MIC90 0.12 ug.mL-1 10.1128/aac.01812-09
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Paecilomyces variotii Paecilomyces variotii MIC nan None 10.1016/j.bmc.2009.07.039
Parvimonas micra Parvimonas micra MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC50 0.03 ug.mL-1 10.1128/aac.00355-08
Parvimonas micra Parvimonas micra MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Pasteurella multocida Pasteurella multocida MIC 0.03 ug.mL-1 10.1128/aac.01522-08
Pasteurella multocida Pasteurella multocida MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC 13.0 ug.mL-1 10.1021/acs.jnatprod.8b00015
Pasteurella multocida Pasteurella multocida MIC 16.0 ug.mL-1 10.1128/aac.01522-08
Pasteurella multocida Pasteurella multocida MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Pasteurella multocida Pasteurella multocida MIC90 0.25 ug.mL-1 10.1128/aac.00149-08
Pectobacterium carotovorum Pectobacterium carotovorum IZ 15.0 mm 10.1007/s00044-013-0837-4
Penicillium expansum Penicillium expansum MIC nan None 10.1016/j.bmc.2009.07.039
Penicillium griseofulvum Penicillium griseofulvum MIC 100.0 ug.mL-1 10.1021/np0602057
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 0.03 ug.mL-1 10.1128/aac.00355-08
Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 0.03 ug.mL-1 10.1128/aac.00355-08
Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 1.0 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 0.0 % 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus Activity 100.0 % 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC 2.0 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC50 128.0 ug.mL-1 10.1128/aac.00355-08
Phocaeicola vulgatus Phocaeicola vulgatus MIC90 128.0 ug.mL-1 10.1128/aac.00355-08
Plasmodium falciparum Plasmodium falciparum Potency 18526.0 nM None
Porphyromonas gingivalis Porphyromonas gingivalis GI nan None 10.1021/np2004775
Porphyromonas gingivalis Porphyromonas gingivalis MBC 2.3 uM 10.1021/acs.jnatprod.6b00831
Porphyromonas gingivalis Porphyromonas gingivalis MIC 290.0 nM 10.1021/acs.jnatprod.6b00831
Prescottella equi Prescottella equi MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Prevotella bivia Prevotella bivia Activity 6.0 % 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia Activity 95.0 % 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC50 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella bivia Prevotella bivia MIC90 64.0 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae Activity 6.0 % 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae Activity 95.0 % 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC50 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella buccae Prevotella buccae MIC90 64.0 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia Activity 6.0 % 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia Activity 95.0 % 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia GI nan None 10.1021/np2004775
Prevotella intermedia Prevotella intermedia MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC50 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella intermedia Prevotella intermedia MIC90 64.0 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica Activity 6.0 % 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica Activity 95.0 % 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC 0.03 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC50 16.0 ug.mL-1 10.1128/aac.00355-08
Prevotella melaninogenica Prevotella melaninogenica MIC90 64.0 ug.mL-1 10.1128/aac.00355-08
Priestia megaterium Priestia megaterium IZ 18.0 mm 10.1016/j.bmcl.2012.05.001
Priestia megaterium Priestia megaterium IZ 18.0 mm 10.1016/j.fitote.2011.12.017
Priestia megaterium Priestia megaterium IZ 25.0 mm 10.1007/s00044-011-9857-0
Priestia megaterium Priestia megaterium IZ 26.0 mm 10.1021/np200330c
Priestia megaterium Priestia megaterium IZ 28.0 mm 10.1021/np300475d
Proteus mirabilis Proteus mirabilis MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Proteus mirabilis Proteus mirabilis MIC 16.0 ug.mL-1 10.1016/j.ejmech.2020.113102
Proteus vulgaris Proteus vulgaris IZ 10.0 mm 10.1016/j.ejmech.2006.09.023
Proteus vulgaris Proteus vulgaris IZ 10.0 mm 10.1016/j.ejmech.2007.01.011
Proteus vulgaris Proteus vulgaris IZ 14.0 mm 10.1016/j.ejmech.2009.07.003
Proteus vulgaris Proteus vulgaris IZ 15.0 mm 10.1007/s00044-013-0837-4
Proteus vulgaris Proteus vulgaris IZ 22.0 mm 10.1016/j.ejmech.2010.01.050
Proteus vulgaris Proteus vulgaris IZ 23.0 mm 10.1007/s00044-011-9857-0
Proteus vulgaris Proteus vulgaris IZ 36.0 mm 10.1016/j.ejmech.2008.02.038
Proteus vulgaris Proteus vulgaris MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Proteus vulgaris Proteus vulgaris MIC 16.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Proteus vulgaris Proteus vulgaris MIC 25000.0 ug.mL-1 10.1016/j.ejmech.2010.01.050
Providencia stuartii Beta-lactamase Activity 0.62 % 10.1128/aac.00218-07
Providencia stuartii Beta-lactamase Activity 43.0 % 10.1128/aac.00218-07
Providencia stuartii Beta-lactamase Kcat 3.3 /s 10.1128/aac.00218-07
Providencia stuartii Beta-lactamase Kcat/Km 0.25 /s/microM 10.1128/aac.00218-07
Providencia stuartii Beta-lactamase Km 14000.0 nM 10.1128/aac.00218-07
Pseudomonas aeruginosa Beta-lactamase Kcat 1.2 /s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Kcat 30.0 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Kcat/Km 300.0 /mM/s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Kcat/Km 860.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase Km 4000.0 nM 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase Km 35000.0 nM 10.1128/aac.01410-08
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Kcat 3.0 /s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Kcat/Km 150.0 /mM/s 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase bla(BEL1) Km 20000.0 nM 10.1128/aac.00859-09
Pseudomonas aeruginosa Beta-lactamase GES-13 Kcat 13.5 /s 10.1128/aac.01561-09
Pseudomonas aeruginosa Beta-lactamase GES-13 Kcat/Km 0.1 /uM/s 10.1128/aac.01561-09
Pseudomonas aeruginosa Beta-lactamase GES-13 Km 139000.0 nM 10.1128/aac.01561-09
Pseudomonas aeruginosa Beta-lactamase IMP-1 Activity 19.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase IMP-1 Activity 520.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase IMP-1 Kcat 1400.0 /s 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase IMP-1 Kcat/Km 2.5 /s/microM 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase IMP-1 Km 550000.0 nM 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase OXA-10 Activity 540.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase OXA-10 Activity 14000.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase OXA-10 Kcat 86.0 /s 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase OXA-10 Kcat/Km 11.0 /s/microM 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase OXA-10 Km 7900.0 nM 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase VIM-1 Kcat 418.0 /s 10.1128/aac.00465-08
Pseudomonas aeruginosa Beta-lactamase VIM-1 Kcat/Km 3.2 /M/s 10.1128/aac.00465-08
Pseudomonas aeruginosa Beta-lactamase VIM-1 Km 1303000.0 nM 10.1128/aac.00465-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity 61.0 % 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity 61.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity 61.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity 570.0 % 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity 570.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa Beta-lactamase VIM-2 Activity 570.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat 73.0 /s 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat 73.0 /s 10.1128/aac.00218-07
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat 73.0 /s 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat 280.0 /s 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km 0.49 /s/microM 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km 0.49 /s/microM 10.1128/aac.00218-07
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km 0.49 /s/microM 10.1128/aac.01004-09
Pseudomonas aeruginosa Beta-lactamase VIM-2 Kcat/Km 4.0 /uM/s 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km 70000.0 nM 10.1128/aac.00166-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km 150000.0 nM 10.1128/aac.00175-08
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km 150000.0 nM 10.1128/aac.00218-07
Pseudomonas aeruginosa Beta-lactamase VIM-2 Km 150000.0 nM 10.1128/aac.01004-09
Pseudomonas aeruginosa Class B carbapenemase VIM-13 Kcat 757.0 /s 10.1128/aac.00465-08
Pseudomonas aeruginosa Class B carbapenemase VIM-13 Kcat/Km 6.7 /M/s 10.1128/aac.00465-08
Pseudomonas aeruginosa Class B carbapenemase VIM-13 Km 1127000.0 nM 10.1128/aac.00465-08
Pseudomonas aeruginosa Metallo beta-lactamase Activity 750.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa Metallo beta-lactamase Kcat/Km 0.56 /s/microM 10.1128/aac.00218-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Kcat 113.0 /s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Kcat/Km 7.4 10'6/M/s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-11 Km 15300.0 nM 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Kcat 141.0 /s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Kcat/Km 7.4 10'6/M/s 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-beta-lactamase VIM-2 Km 19100.0 nM 10.1128/aac.01025-07
Pseudomonas aeruginosa Metallo-b-lactamase Kcat 430.0 /s 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-b-lactamase Kcat/Km 25.0 /uM/s 10.1128/aac.00166-08
Pseudomonas aeruginosa Metallo-b-lactamase Km 17000.0 nM 10.1128/aac.00166-08
Pseudomonas aeruginosa Pseudomonas aeruginosa DIZ nan None 10.1016/j.ejmech.2017.11.025
Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 6.25 ug.mL-1 10.1016/j.ejmech.2009.04.014
Pseudomonas aeruginosa Pseudomonas aeruginosa IC50 631000.0 nM 10.1016/j.ejmech.2018.12.017
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 0.0 mm 10.1016/j.ejmech.2008.02.027
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 6.0 mm 10.1007/s00044-010-9345-y
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 6.0 mm 10.1016/j.ejmech.2017.11.001
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 8.0 mm 10.1016/j.ejmech.2006.09.023
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 8.0 mm 10.1016/j.ejmech.2007.01.011
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 12.0 mm 10.1007/s00044-010-9345-y
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 13.0 mm 10.1007/s00044-010-9440-0
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 14.0 mm 10.1016/j.ejmech.2008.02.038
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 22.0 mm 10.1007/s00044-010-9440-0
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 23.0 mm 10.1007/s00044-010-9530-z
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 23.0 mm 10.1021/acs.jnatprod.9b00475
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 25.0 mm 10.1248/cpb.57.685
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 28.0 mm 10.1007/s00044-010-9530-z
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 28.3 mm 10.1016/j.ejmech.2011.07.035
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 28.3 mm 10.1016/j.ejmech.2016.11.019
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 28.32 mm 10.1016/j.ejmech.2011.08.018
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 30.0 mm 10.1016/j.ejmech.2012.03.004
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 36.0 mm 10.1016/j.ejmech.2009.07.003
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 38.0 mm 10.1007/s00044-013-0568-6
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ nan None 10.1007/s00044-009-9177-9
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ nan None 10.1016/j.bmcl.2006.05.021
Pseudomonas aeruginosa Pseudomonas aeruginosa MBC 12.5 ug ml-1 10.1248/cpb.57.685
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.097 ug.mL-1 10.1007/s00044-012-0294-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1007/s00044-012-0028-8
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.04.024
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.25 ug.mL-1 10.1007/s00044-013-0568-6
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 0.5 ug.mL-1 10.1016/j.bmcl.2020.127301
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.0 ug.mL-1 10.1021/np060444u
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 1.56 ug.mL-1 10.1016/j.ejmech.2016.02.030
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.125 ug.mL-1 10.1016/j.ejmech.2020.112666
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.2 ug.mL-1 10.1016/j.ejmech.2010.03.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmc.2011.06.077
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmc.2015.07.075
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmcl.2005.09.009
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmcl.2009.09.111
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmcl.2010.01.032
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmcl.2010.05.105
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmcl.2013.05.006
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.bmcl.2013.09.086
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.ejmech.2008.04.019
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.ejmech.2013.11.020
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.ejmech.2014.01.018
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.ejmech.2020.112994
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1039/C4MD00238E
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1248/cpb.57.685
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 7.82 ug.mL-1 10.1016/j.ejmech.2020.112994
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 9.37 ug.mL-1 10.1007/s00044-012-0332-3
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1007/s00044-010-9367-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1007/s00044-012-0168-x
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1007/s00044-012-0408-0
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.bmcl.2004.12.020
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.bmcl.2010.10.003
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.bmcl.2011.05.036
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.bmcl.2011.08.075
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.bmcl.2017.06.004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.ejmech.2009.07.002
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.ejmech.2009.09.027
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.ejmech.2010.04.016
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 12.5 ug.mL-1 10.1016/j.ejmech.2013.07.013
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 16.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 18.62 ug.mL-1 10.1016/j.bmc.2014.03.004
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 21.96 ug.mL-1 10.1016/j.bmc.2014.09.048
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 50.0 ug.mL-1 10.1007/s00044-004-0035-5
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 50.0 ug.mL-1 10.1016/j.ejmech.2010.08.024
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.07.042
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1016/j.bmcl.2020.127301
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm000213z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/jm980476h
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128.0 ug.mL-1 10.1021/np010076o
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 250.0 ug.mL-1 10.1021/acs.jnatprod.0c01309
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 256.0 ug.mL-1 10.1039/d2md00041e
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 560.0 ug.mL-1 10.1021/np9805084
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 2048.0 ug.mL-1 10.1128/aac.00710-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 4096.0 ug.mL-1 10.1128/aac.00710-10
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 18700.0 nM 10.1016/j.ejmech.2012.03.054
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 18700.0 nM 10.1016/j.ejmech.2012.09.003
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 27800.0 nM 10.1021/acs.jnatprod.9b00475
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 37380.0 nM 10.1016/j.ejmech.2014.06.075
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 64000.0 nM 10.1021/acs.jmedchem.1c00614
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 95810.0 nM 10.1016/j.ejmech.2019.01.038
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100000.0 nM 10.1016/j.bmcl.2012.04.018
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 128000.0 nM 10.1016/j.ejmech.2019.111636
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 383230.0 nM 10.1016/j.ejmech.2019.01.038
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 500000.0 nM 10.1016/j.bmc.2015.10.029
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1007/s00044-012-0408-0
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1016/j.bmc.2009.07.039
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1016/j.bmcl.2011.06.081
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1016/j.bmcl.2015.07.044
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1016/j.ejmech.2019.01.038
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1128/aac.01436-08
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC90 100000.0 nM 10.1016/j.bmcl.2013.03.053
Pseudomonas aeruginosa Pseudomonas aeruginosa MPC 1.03 ug ml-1 10.1021/jm000213z
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 1.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 35.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 37.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 46.0 % 10.1128/aac.01004-09
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 61.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 91.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 540.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 670.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 1100.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Activity 14000.0 % 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 15.0 /s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 20.0 /s 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 37.0 /s 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 44.0 /s 10.1128/aac.01004-09
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 45.0 /s 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat 86.0 /s 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 1.1 /s/microM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 3.1 /s/microM 10.1128/aac.01004-09
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 3.4 /s/microM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 6.7 /s/microM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 11.0 /s/microM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Kcat/Km 430.0 /uM/s 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 3000.0 nM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 7900.0 nM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 11000.0 nM 10.1128/aac.00218-07
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 14000.0 nM 10.1128/aac.01004-09
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 35000.0 nM 10.1128/aac.01410-08
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) Beta-lactamase Km 40000.0 nM 10.1128/aac.00218-07
Pseudomonas amygdali pv. lachrymans Pseudomonas amygdali pv. lachrymans MIC 250.0 ug.mL-1 10.1016/j.bmcl.2016.06.015
Pseudomonas fluorescens Beta-lactamase Kcat/Km 660.0 /mM/s 10.1128/aac.00961-09
Pseudomonas fluorescens Pseudomonas fluorescens MIC 6.25 ug.mL-1 10.1016/j.ejmech.2008.01.013
Pseudomonas fluorescens Pseudomonas fluorescens MIC 50.0 ug.mL-1 10.1016/j.ejmech.2007.05.013
Pseudomonas luteola Beta-lactamase Kcat 31.0 /s 10.1128/aac.00427-09
Pseudomonas luteola Beta-lactamase Kcat/Km 3.87 /s/microM 10.1128/aac.00427-09
Pseudomonas luteola Beta-lactamase Km 8000.0 nM 10.1128/aac.00427-09
Pseudomonas stutzeri Metallo-beta-lactamase Kcat 250.0 /s 10.1128/aac.01456-09
Pseudomonas stutzeri Metallo-beta-lactamase Km 90000.0 nM 10.1128/aac.01456-09
Pseudomonas stutzeri Metallo-beta-lactamase Ratio 2800.0 None 10.1128/aac.01456-09
Ralstonia solanacearum Ralstonia solanacearum MIC 250.0 ug.mL-1 10.1016/j.bmcl.2016.06.015
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Oligopeptide transporter, kidney isoform Ki 11100000.0 nM 10.1016/j.ejpb.2004.07.008
Rattus norvegicus Plasma logFu 0.425 None 10.1016/j.ejmech.2009.06.004
Rattus norvegicus Rattus norvegicus ALB 41300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 45000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 354.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 366.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 371.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 376.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 48.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 49.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 50.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 56.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 69.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 76.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 81.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 88.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 133.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 136.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 163.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 103.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 104.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 626.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 793.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 826.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 122.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 183.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 245.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 330.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 21670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 24330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 26670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Concentration 0.3 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 0.4 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 0.7 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 0.9 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 1.1 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 1.3 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 1.4 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 2.3 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 2.7 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 2.8 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 2.9 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 6.2 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 7.5 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 8.5 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 9.5 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 15.1 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 17.7 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 20.8 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 22.4 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 22.8 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 25.2 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 27.6 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 30.3 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 30.7 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 33.6 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 38.9 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 52.5 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 64.6 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 88.5 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration 120.5 ug ml-1 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus Concentration nan None 10.1021/jm00128a020
Rattus norvegicus Rattus norvegicus CREAT 1.4 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 4.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 74.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 77.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 223.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1516.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1640.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1720.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1743.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 35.13 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.13 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.07 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.47 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 134000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 134300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 137300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 138000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 98.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 117.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 124.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 357.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10602.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11415.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 11488.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13141.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 87.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 88.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 92.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 94.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.6 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.63 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.07 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 368700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 370700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 371700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 381700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.1 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.7 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.07 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.8 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 123.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 166.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 332.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 398.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 4.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 5.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 7.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 512.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 717.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 974.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1318.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 123.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 126.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 132.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 137.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1103670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1280330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1362000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1442000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.23 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.53 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.79 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.91 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5570000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5580000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5820000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5850000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.2 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 144.97 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 146.57 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 15.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 16.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 19.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 20.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12130.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12170.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 12330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 14930.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Solute carrier family 22 member 6 Activity nan None None
Rattus norvegicus Solute carrier family 22 member 6 Ki 418000.0 nM 10.1124/jpet.300.3.746
Rattus norvegicus Solute carrier family 22 member 6 Ki 1680000.0 nM None
Rattus norvegicus Solute carrier family 22 member 8 Activity 1.01 % 10.1097/00004647-200304000-00007
Rattus norvegicus Solute carrier family 22 member 8 Activity nan None 10.1074/jbc.274.19.13675
Rattus norvegicus Solute carrier family 22 member 8 Ki 52800.0 nM 10.1124/jpet.300.3.746
Rattus norvegicus Solute carrier family 22 member 8 Km 82600.0 nM 10.1124/mol.61.5.982
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC nan None 10.1016/j.bmc.2009.07.039
Salmonella Salmonella MIC 10.0 ug.mL-1 10.1021/jm00224a026
Salmonella enterica Salmonella enterica IZ 37.0 mm 10.1016/j.bmcl.2006.05.021
Salmonella enterica subsp. enterica serovar Enteritidis Salmonella enteritidis MIC nan None 10.1016/j.bmc.2009.07.039
Salmonella enterica subsp. enterica serovar Paratyphi B Salmonella enterica subsp. enterica serovar Paratyphi B MIC 2.0 ug.mL-1 10.1016/j.ejmech.2011.07.042
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 20.0 mm 10.1007/s00044-011-9944-2
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi IZ 24.0 mm 10.1007/s00044-011-9944-2
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 50.0 ug.mL-1 10.1007/s00044-011-9573-9
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC 128.0 ug.mL-1 10.1021/jm980476h
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium IZ 22.0 mm 10.1016/j.ejmech.2020.113034
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 16.0 ug.mL-1 10.1128/aac.01472-06
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC 125.0 ug.mL-1 10.1016/j.bmcl.2013.09.082
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Ratio 32.0 None 10.1016/j.ejmech.2012.03.008
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Kcat 135.0 /s 10.1128/aac.01581-08
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Kcat/Km 13.5 /s/microM 10.1128/aac.01581-08
Salmonella enterica subsp. enterica serovar Westhampton Extended-spectrum beta-lactamase CTX-M-53 Km 10000.0 nM 10.1128/aac.01581-08
Salmonella newport Efflux transporter Kcat 7.7 /s 10.1128/aac.01284-08
Salmonella newport Efflux transporter Kcat/Km 25.7 /uM/s 10.1128/aac.01284-08
Salmonella newport Efflux transporter Km 300.0 nM 10.1128/aac.01284-08
Salmonella sp. Salmonella sp. MIC 31.25 ug.mL-1 10.1016/j.bmcl.2013.09.082
Serratia marcescens Beta-lactamase Activity 0.95 % 10.1128/aac.00218-07
Serratia marcescens Beta-lactamase Activity 290.0 % 10.1128/aac.00218-07
Serratia marcescens Beta-lactamase Kcat 19.0 /s 10.1128/aac.00218-07
Serratia marcescens Beta-lactamase Kcat/Km 9.0 /s/microM 10.1128/aac.00218-07
Serratia marcescens Beta-lactamase Km 2100.0 nM 10.1128/aac.00218-07
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Activity 0.73 % 10.1128/aac.00218-07
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Activity 0.73 % 10.1128/aac.01004-09
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Activity 130.0 % 10.1128/aac.00218-07
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Activity 130.0 % 10.1128/aac.01004-09
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Kcat 8.8 /s 10.1128/aac.00218-07
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Kcat 8.8 /s 10.1128/aac.01004-09
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Kcat/Km 4.0 /s/microM 10.1128/aac.00218-07
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Kcat/Km 4.0 /s/microM 10.1128/aac.01004-09
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Km 2200.0 nM 10.1128/aac.00218-07
Serratia marcescens Carbapenem-hydrolyzing beta-lactamase SME-3 Km 2200.0 nM 10.1128/aac.01004-09
Serratia marcescens Serratia marcescens IZ 7.0 mm 10.1016/j.ejmech.2012.03.004
Serratia marcescens Serratia marcescens IZ 8.0 mm 10.1016/j.ejmech.2017.11.001
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.164 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Shigella sp. Shigella sp. MIC 6.25 ug.mL-1 10.1021/jm00346a024
Shouchella clausii Shouchella clausii MIC 500.0 ug.mL-1 10.1128/aac.00537-07
Stachybotrys chartarum Stachybotrys chartarum MIC 100.0 ug.mL-1 10.1021/np0602057
Staphylococcus Staphylococcus MIC 2000.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus aureus Beta-lactamase Activity 46000.0 % 10.1128/aac.00218-07
Staphylococcus aureus Beta-lactamase Activity 1500000.0 % 10.1128/aac.00218-07
Staphylococcus aureus Beta-lactamase Kcat 65.0 /s 10.1128/aac.00218-07
Staphylococcus aureus Beta-lactamase Kcat/Km 19.0 /s/microM 10.1128/aac.00218-07
Staphylococcus aureus Beta-lactamase Km 3400.0 nM 10.1128/aac.00218-07
Staphylococcus aureus Beta-lactamase Km 12000.0 nM 10.1021/jm00369a001
Staphylococcus aureus MecA IC50 2.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 4.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA IC50 64.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus MecA Inhibition 13.0 % 10.1016/j.ejmech.2008.10.016
Staphylococcus aureus Staphylococcus aureus Activity 0.5 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 2.3 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 16.7 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 32.3 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 67.7 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 80.0 % 10.1128/aac.00629-07
Staphylococcus aureus Staphylococcus aureus Activity 83.3 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 97.7 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 99.5 % 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus Activity 100.0 % 10.1128/aac.00351-10
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1016/j.bmc.2006.12.027
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/acsmedchemlett.1c00648
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/jm0703183
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1021/np030074z
Staphylococcus aureus Staphylococcus aureus Activity nan None 10.1128/aac.01436-08
Staphylococcus aureus Staphylococcus aureus DIZ nan None 10.1016/j.ejmech.2017.11.025
Staphylococcus aureus Staphylococcus aureus ED50 135.0 mg.kg-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus IC50 1.562 ug.mL-1 10.1016/j.ejmech.2009.04.014
Staphylococcus aureus Staphylococcus aureus IC50 631000.0 nM 10.1016/j.ejmech.2018.12.017
Staphylococcus aureus Staphylococcus aureus IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Staphylococcus aureus Staphylococcus aureus IZ 6.0 mm 10.1007/s00044-010-9345-y
Staphylococcus aureus Staphylococcus aureus IZ 8.0 % 10.1007/s00044-010-9425-z
Staphylococcus aureus Staphylococcus aureus IZ 8.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 9.0 mm 10.1016/j.bmcl.2015.12.012
Staphylococcus aureus Staphylococcus aureus IZ 9.38 mm 10.1016/j.ejmech.2008.02.027
Staphylococcus aureus Staphylococcus aureus IZ 10.0 mm 10.1016/j.ejmech.2019.111744
Staphylococcus aureus Staphylococcus aureus IZ 10.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 12.0 % 10.1007/s00044-010-9425-z
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mm 10.1007/s00044-010-9345-y
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mm 10.1007/s00044-010-9440-0
Staphylococcus aureus Staphylococcus aureus IZ 12.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1016/j.ejmech.2006.09.023
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1016/j.ejmech.2007.01.011
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1016/j.ejmech.2008.02.038
Staphylococcus aureus Staphylococcus aureus IZ 13.0 mm 10.1016/j.ejmech.2009.07.003
Staphylococcus aureus Staphylococcus aureus IZ 14.0 mm 10.1016/j.bmc.2008.05.032
Staphylococcus aureus Staphylococcus aureus IZ 14.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 15.0 mm 10.1007/s00044-013-0837-4
Staphylococcus aureus Staphylococcus aureus IZ 15.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 16.0 mm 10.1016/j.ejmech.2013.08.032
Staphylococcus aureus Staphylococcus aureus IZ 16.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 17.0 mm 10.1016/j.bmcl.2015.12.012
Staphylococcus aureus Staphylococcus aureus IZ 19.0 mm 10.1016/j.bmc.2007.05.037
Staphylococcus aureus Staphylococcus aureus IZ 19.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 20.0 mm 10.1016/j.ejmech.2010.01.050
Staphylococcus aureus Staphylococcus aureus IZ 21.0 mm 10.1007/s00044-010-9440-0
Staphylococcus aureus Staphylococcus aureus IZ 22.0 mm 10.1021/np970338f
Staphylococcus aureus Staphylococcus aureus IZ 24.0 mm 10.1007/s00044-011-9857-0
Staphylococcus aureus Staphylococcus aureus IZ 24.0 mm 10.1016/j.ejmech.2020.113034
Staphylococcus aureus Staphylococcus aureus IZ 24.6 mm 10.1016/j.ejmech.2019.111744
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1007/s00044-010-9530-z
Staphylococcus aureus Staphylococcus aureus IZ 25.0 mm 10.1021/acs.jnatprod.5b00380
Staphylococcus aureus Staphylococcus aureus IZ 28.0 mm 10.1016/j.bmcl.2017.09.052
Staphylococcus aureus Staphylococcus aureus IZ 28.0 mm 10.1021/acs.jnatprod.9b00475
Staphylococcus aureus Staphylococcus aureus IZ 28.0 mm 10.1128/aac.00629-07
Staphylococcus aureus Staphylococcus aureus IZ 29.0 mm 10.1128/aac.00629-07
Staphylococcus aureus Staphylococcus aureus IZ 29.4 mm 10.1016/j.ejmech.2011.07.035
Staphylococcus aureus Staphylococcus aureus IZ 29.48 mm 10.1016/j.ejmech.2011.08.018
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1007/s00044-010-9530-z
Staphylococcus aureus Staphylococcus aureus IZ 30.0 mm 10.1016/j.bmcl.2015.02.044
Staphylococcus aureus Staphylococcus aureus IZ 30.1 mm 10.1016/j.ejmech.2016.11.019
Staphylococcus aureus Staphylococcus aureus IZ 33.0 mm 10.1016/j.bmc.2008.05.032
Staphylococcus aureus Staphylococcus aureus IZ 33.0 mM 10.1016/j.bmcl.2006.01.058
Staphylococcus aureus Staphylococcus aureus IZ 40.0 mm 10.1007/s00044-010-9450-y
Staphylococcus aureus Staphylococcus aureus IZ 40.0 mm 10.1016/j.ejmech.2012.03.004
Staphylococcus aureus Staphylococcus aureus IZ 40.0 mm 10.1248/cpb.57.685
Staphylococcus aureus Staphylococcus aureus IZ 45.0 mm 10.1007/s00044-013-0568-6
Staphylococcus aureus Staphylococcus aureus IZ nan None 10.1016/j.bmcl.2006.05.021
Staphylococcus aureus Staphylococcus aureus MBC 0.5 ug ml-1 10.1021/acs.jmedchem.6b00580
Staphylococcus aureus Staphylococcus aureus MBC 6.25 ug ml-1 10.1248/cpb.57.685
Staphylococcus aureus Staphylococcus aureus MIC 0.012 ug.mL-1 10.1016/j.bmc.2007.11.052
Staphylococcus aureus Staphylococcus aureus MIC 0.012 ug.mL-1 10.1016/j.bmcl.2007.03.077
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1016/j.bmc.2008.05.032
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1021/np020380x
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1128/aac.01091-09
Staphylococcus aureus Staphylococcus aureus MIC 0.03 ug.mL-1 10.1128/aac.01192-06
Staphylococcus aureus Staphylococcus aureus MIC 0.031 ug.mL-1 10.1016/j.ejmech.2011.07.042
Staphylococcus aureus Staphylococcus aureus MIC 0.049 ug.mL-1 10.1021/np50088a008
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1016/S0960-894X(01)80948-3
Staphylococcus aureus Staphylococcus aureus MIC 0.05 ug.mL-1 10.1021/jm00142a024
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1016/j.ejmech.2020.113134
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/np010076o
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/np020044g
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/np030314a
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1021/np400759f
Staphylococcus aureus Staphylococcus aureus MIC 0.06 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2010.04.123
Staphylococcus aureus Staphylococcus aureus MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus aureus Staphylococcus aureus MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 0.063 ug.mL-1 10.1016/j.ejmech.2016.12.054
Staphylococcus aureus Staphylococcus aureus MIC 0.065 ug.mL-1 10.1021/jm00369a001
Staphylococcus aureus Staphylococcus aureus MIC 0.097 ug.mL-1 10.1007/s00044-012-0294-5
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1007/s00044-012-0028-8
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1016/j.ejmech.2012.04.024
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1021/np400759f
Staphylococcus aureus Staphylococcus aureus MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1007/s00044-013-0568-6
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1016/j.bmc.2019.02.024
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1021/np5000457
Staphylococcus aureus Staphylococcus aureus MIC 0.125 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2012.04.056
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2016.06.015
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1021/acs.jnatprod.0c01309
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.00859-08
Staphylococcus aureus Staphylococcus aureus MIC 0.25 ug.mL-1 10.1128/aac.01192-06
Staphylococcus aureus Staphylococcus aureus MIC 0.26 ug.mL-1 10.1021/acs.jnatprod.9b00315
Staphylococcus aureus Staphylococcus aureus MIC 0.39 ug.mL-1 10.1016/j.bmc.2009.07.039
Staphylococcus aureus Staphylococcus aureus MIC 0.39 ug.mL-1 10.1016/j.ejmech.2020.112666
Staphylococcus aureus Staphylococcus aureus MIC 0.4 ug.mL-1 10.1021/jm980476h
Staphylococcus aureus Staphylococcus aureus MIC 0.46 ug.mL-1 10.1016/j.bmcl.2017.09.052
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1016/s0960-894x(99)00127-4
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.6b00580
Staphylococcus aureus Staphylococcus aureus MIC 0.5 ug.mL-1 10.1021/acs.jnatprod.0c01309
Staphylococcus aureus Staphylococcus aureus MIC 0.51 ug.mL-1 10.1021/jm000213z
Staphylococcus aureus Staphylococcus aureus MIC 0.78 ug.mL-1 10.1016/j.bmc.2015.07.075
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmc.2007.08.035
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2010.04.123
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 1.0 ug.mL-1 10.1128/aac.00859-08
Staphylococcus aureus Staphylococcus aureus MIC 1.024 ug.mL-1 10.1016/j.bmc.2014.03.004
Staphylococcus aureus Staphylococcus aureus MIC 1.39 ug.mL-1 10.1016/j.ejmech.2010.01.066
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1016/j.ejmech.2016.02.030
Staphylococcus aureus Staphylococcus aureus MIC 1.56 ug.mL-1 10.1248/cpb.57.685
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1007/s00044-010-9367-5
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1007/s00044-012-0168-x
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1007/s00044-012-0408-0
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2004.12.020
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2005.09.009
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2009.09.111
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.01.032
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.10.003
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.12.024
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2011.05.036
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2011.08.075
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.bmcl.2017.06.004
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.ejmech.2008.01.013
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.ejmech.2008.04.019
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.ejmech.2009.07.002
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.ejmech.2010.07.036
Staphylococcus aureus Staphylococcus aureus MIC 1.562 ug.mL-1 10.1016/j.ejmech.2013.07.013
Staphylococcus aureus Staphylococcus aureus MIC 1.685 ug.mL-1 10.1016/j.bmc.2014.09.048
Staphylococcus aureus Staphylococcus aureus MIC 1.96 ug.mL-1 10.1016/j.ejmech.2020.112994
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2007.05.013
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2007.11.026
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2010.03.027
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 2.0 ug.mL-1 10.1128/aac.00361-10
Staphylococcus aureus Staphylococcus aureus MIC 3.91 ug.mL-1 10.1016/j.bmcl.2013.09.082
Staphylococcus aureus Staphylococcus aureus MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.2c00684
Staphylococcus aureus Staphylococcus aureus MIC 6.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1007/s00044-012-0332-3
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.bmc.2011.06.077
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.bmcl.2010.05.105
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.bmcl.2013.05.006
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.bmcl.2013.09.086
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2009.09.027
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2010.04.016
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2013.11.020
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2014.01.018
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2020.112994
Staphylococcus aureus Staphylococcus aureus MIC 6.25 ug.mL-1 10.1039/C4MD00238E
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00361-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.00464-10
Staphylococcus aureus Staphylococcus aureus MIC 8.0 ug.mL-1 10.1128/aac.01128-08
Staphylococcus aureus Staphylococcus aureus MIC 10.0 ug.mL-1 10.1021/jm00224a026
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1016/j.ejmech.2010.08.024
Staphylococcus aureus Staphylococcus aureus MIC 12.5 ug.mL-1 10.1021/jm00346a024
Staphylococcus aureus Staphylococcus aureus MIC 13.0 ug.mL-1 10.1021/acs.jnatprod.8b00015
Staphylococcus aureus Staphylococcus aureus MIC 14.0 ug.mL-1 10.1021/np9805084
Staphylococcus aureus Staphylococcus aureus MIC 15.6 ug.mL-1 10.1016/j.bmcl.2013.08.059
Staphylococcus aureus Staphylococcus aureus MIC 15.6 ug.mL-1 10.1016/j.ejmech.2010.09.045
Staphylococcus aureus Staphylococcus aureus MIC 15.63 ug.mL-1 10.1016/j.bmc.2019.115088
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmc.2007.11.052
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.bmcl.2007.03.077
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2013.08.032
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2016.12.054
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.00859-08
Staphylococcus aureus Staphylococcus aureus MIC 16.0 ug.mL-1 10.1128/aac.01091-09
Staphylococcus aureus Staphylococcus aureus MIC 31.25 ug.mL-1 10.1016/j.bmcl.2013.08.059
Staphylococcus aureus Staphylococcus aureus MIC 31.25 ug.mL-1 10.1016/j.ejmech.2010.09.045
Staphylococcus aureus Staphylococcus aureus MIC 31.3 ug.mL-1 10.1016/j.bmcl.2010.12.084
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.00859-08
Staphylococcus aureus Staphylococcus aureus MIC 32.0 ug.mL-1 10.1128/aac.01472-06
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1007/s00044-011-9573-9
Staphylococcus aureus Staphylococcus aureus MIC 50.0 ug.mL-1 10.1021/jm00142a024
Staphylococcus aureus Staphylococcus aureus MIC 62.5 ug.mL-1 10.1016/j.bmcl.2013.08.059
Staphylococcus aureus Staphylococcus aureus MIC 62.5 ug.mL-1 10.1016/j.ejmech.2010.09.045
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmc.2008.05.032
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmc.2019.02.024
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.04.123
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.bmcl.2012.04.056
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2011.07.042
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/jm00369a001
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/np010076o
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00019-10
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1128/aac.00026-09
Staphylococcus aureus Staphylococcus aureus MIC 79.0 ug.mL-1 10.1021/jm00126a041
Staphylococcus aureus Staphylococcus aureus MIC 100.0 nM 10.1016/j.ejmech.2007.10.007
Staphylococcus aureus Staphylococcus aureus MIC 125.0 ug.mL-1 10.1016/j.bmcl.2013.08.059
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/jm000213z
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/np020044g
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/np020380x
Staphylococcus aureus Staphylococcus aureus MIC 128.0 ug.mL-1 10.1021/np030314a
Staphylococcus aureus Staphylococcus aureus MIC 250.0 ug.mL-1 10.1016/j.bmcl.2013.08.059
Staphylococcus aureus Staphylococcus aureus MIC 370.0 nM 10.1016/j.ejmech.2019.01.038
Staphylococcus aureus Staphylococcus aureus MIC 500.0 nM 10.1016/j.bmcl.2012.04.018
Staphylococcus aureus Staphylococcus aureus MIC 500.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
Staphylococcus aureus Staphylococcus aureus MIC 560.0 ug.mL-1 10.1021/np9805084
Staphylococcus aureus Staphylococcus aureus MIC 749.0 nM 10.1021/acsmedchemlett.7b00431
Staphylococcus aureus Staphylococcus aureus MIC 800.0 ug.mL-1 10.1021/np50088a008
Staphylococcus aureus Staphylococcus aureus MIC 980.0 nM 10.1016/j.bmc.2014.05.064
Staphylococcus aureus Staphylococcus aureus MIC 980.0 nM 10.1016/j.bmc.2014.12.019
Staphylococcus aureus Staphylococcus aureus MIC 980.0 nM 10.1016/j.bmc.2015.10.029
Staphylococcus aureus Staphylococcus aureus MIC 980.0 nM 10.1016/j.bmc.2016.02.004
Staphylococcus aureus Staphylococcus aureus MIC 1000.0 nM 10.1016/j.ejmech.2019.111636
Staphylococcus aureus Staphylococcus aureus MIC 1000.0 nM 10.1021/acs.jmedchem.1c00614
Staphylococcus aureus Staphylococcus aureus MIC 1000.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus aureus Staphylococcus aureus MIC 3500.0 nM 10.1021/acs.jnatprod.9b00475
Staphylococcus aureus Staphylococcus aureus MIC 4600.0 nM 10.1016/j.ejmech.2012.03.054
Staphylococcus aureus Staphylococcus aureus MIC 4600.0 nM 10.1016/j.ejmech.2012.09.003
Staphylococcus aureus Staphylococcus aureus MIC 6600.0 nM 10.1016/j.bmcl.2011.12.051
Staphylococcus aureus Staphylococcus aureus MIC 7130.0 nM 10.1016/j.ejmech.2015.08.025
Staphylococcus aureus Staphylococcus aureus MIC 9280.0 nM 10.1016/j.ejmech.2015.08.025
Staphylococcus aureus Staphylococcus aureus MIC 22400.0 nM 10.1021/np050372r
Staphylococcus aureus Staphylococcus aureus MIC 23900.0 nM 10.1016/j.bmcl.2011.06.081
Staphylococcus aureus Staphylococcus aureus MIC 25000.0 ug.mL-1 10.1016/j.ejmech.2010.01.050
Staphylococcus aureus Staphylococcus aureus MIC 32000.0 nM 10.1016/j.ejmech.2019.111636
Staphylococcus aureus Staphylococcus aureus MIC 62500.0 nM 10.1016/j.bmc.2014.05.064
Staphylococcus aureus Staphylococcus aureus MIC 62500.0 nM 10.1016/j.bmc.2014.12.019
Staphylococcus aureus Staphylococcus aureus MIC 62500.0 nM 10.1016/j.bmc.2015.10.029
Staphylococcus aureus Staphylococcus aureus MIC 62500.0 nM 10.1016/j.bmc.2016.02.004
Staphylococcus aureus Staphylococcus aureus MIC 95810.0 nM 10.1016/j.ejmech.2019.01.038
Staphylococcus aureus Staphylococcus aureus MIC 100000.0 nM 10.1016/j.bmcl.2011.06.081
Staphylococcus aureus Staphylococcus aureus MIC 125000.0 nM 10.1016/j.bmc.2014.05.064
Staphylococcus aureus Staphylococcus aureus MIC 125000.0 nM 10.1016/j.bmc.2014.12.019
Staphylococcus aureus Staphylococcus aureus MIC 125000.0 nM 10.1016/j.bmc.2015.10.029
Staphylococcus aureus Staphylococcus aureus MIC 125000.0 nM 10.1016/j.bmc.2016.02.004
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1007/s00044-012-0408-0
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1016/j.bmcl.2015.07.044
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1128/aac.00859-08
Staphylococcus aureus Staphylococcus aureus MIC50 0.5 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 4.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 8.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC50 16.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC80 0.01 ug.mL-1 10.1021/np401094h
Staphylococcus aureus Staphylococcus aureus MIC90 2.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC90 16.0 ug.mL-1 10.1128/aac.00149-08
Staphylococcus aureus Staphylococcus aureus MIC90 125.0 nM 10.1016/j.bmcl.2013.03.053
Staphylococcus aureus Staphylococcus aureus MIC95 0.98 umol/L 10.1016/j.bmc.2013.12.016
Staphylococcus aureus Staphylococcus aureus MIC95 62.5 umol/L 10.1016/j.bmc.2013.12.016
Staphylococcus aureus Staphylococcus aureus MIC95 125.0 umol/L 10.1016/j.bmc.2013.12.016
Staphylococcus aureus Staphylococcus aureus MPC 1.85 ug ml-1 10.1021/jm000213z
Staphylococcus aureus Staphylococcus aureus RHR 100.0 None 10.1021/jm00369a001
Staphylococcus epidermidis Staphylococcus epidermidis DIZ nan None 10.1016/j.ejmech.2017.11.025
Staphylococcus epidermidis Staphylococcus epidermidis IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Staphylococcus epidermidis Staphylococcus epidermidis IZ 26.0 mm 10.1021/acs.jnatprod.9b00475
Staphylococcus epidermidis Staphylococcus epidermidis MIC 0.52 ug.mL-1 10.1021/acs.jnatprod.9b00315
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2020.113102
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.562 ug.mL-1 10.1016/j.bmcl.2010.12.024
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1.562 ug.mL-1 10.1016/j.ejmech.2010.07.036
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.04.123
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2014.07.106
Staphylococcus epidermidis Staphylococcus epidermidis MIC 2.0 ug.mL-1 10.1016/j.ejmech.2015.06.008
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1007/s00044-010-9367-5
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1007/s00044-012-0168-x
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1007/s00044-012-0332-3
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.bmcl.2010.10.003
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.bmcl.2011.05.036
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.bmcl.2011.08.075
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.bmcl.2017.06.004
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.ejmech.2009.09.027
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.ejmech.2010.04.016
Staphylococcus epidermidis Staphylococcus epidermidis MIC 3.125 ug.mL-1 10.1016/j.ejmech.2013.07.013
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus epidermidis Staphylococcus epidermidis MIC 4.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 8.0 ug.mL-1 10.1016/j.ejmech.2016.12.054
Staphylococcus epidermidis Staphylococcus epidermidis MIC 16.0 ug.mL-1 10.1016/j.ejmech.2011.07.042
Staphylococcus epidermidis Staphylococcus epidermidis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.01.075
Staphylococcus epidermidis Staphylococcus epidermidis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.05.061
Staphylococcus epidermidis Staphylococcus epidermidis MIC 32.0 ug.mL-1 10.1016/j.bmcl.2009.06.077
Staphylococcus epidermidis Staphylococcus epidermidis MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Staphylococcus epidermidis Staphylococcus epidermidis MIC 1000.0 ug.mL-1 10.1128/aac.01436-08
Staphylococcus epidermidis Staphylococcus epidermidis MIC 7000.0 nM 10.1021/acs.jnatprod.9b00475
Staphylococcus epidermidis Staphylococcus epidermidis MIC 16000.0 nM 10.1021/acs.jmedchem.1c00614
Staphylococcus epidermidis Staphylococcus epidermidis MIC 250000.0 nM 10.1016/j.bmc.2014.05.064
Staphylococcus epidermidis Staphylococcus epidermidis MIC 250000.0 nM 10.1016/j.bmc.2014.12.019
Staphylococcus epidermidis Staphylococcus epidermidis MIC 250000.0 nM 10.1016/j.bmc.2015.10.029
Staphylococcus epidermidis Staphylococcus epidermidis MIC 250000.0 nM 10.1016/j.bmc.2016.02.004
Staphylococcus epidermidis Staphylococcus epidermidis MIC nan None 10.1016/j.bmcl.2015.07.044
Staphylococcus epidermidis Staphylococcus epidermidis MIC95 125.0 uM 10.1016/j.bmcl.2013.12.054
Staphylococcus epidermidis Staphylococcus epidermidis MIC95 250.0 uM 10.1016/j.bmcl.2013.12.054
Staphylococcus epidermidis Staphylococcus epidermidis MIC95 250.0 umol/L 10.1016/j.bmc.2013.12.016
Staphylococcus haemolyticus Staphylococcus haemolyticus MIC 0.0078 ug.mL-1 10.1016/j.ejmech.2016.12.054
Staphylococcus intermedius Staphylococcus intermedius MIC 0.25 ug.mL-1 10.1128/aac.00336-08
Staphylococcus intermedius Staphylococcus intermedius MIC50 0.5 ug.mL-1 10.1128/aac.00336-08
Staphylococcus intermedius Staphylococcus intermedius MIC90 0.5 ug.mL-1 10.1128/aac.00336-08
Stenotrophomonas maltophilia Beta-lactamase L1 Kcat/Km 2.2 10'7/M/s 10.1128/aac.01062-07
Streptococcus Streptococcus Activity 0.0 % 10.1128/aac.00952-09
Streptococcus Streptococcus Activity 6.0 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 71.7 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 99.9 % 10.1128/aac.01453-08
Streptococcus Streptococcus Activity 100.0 % 10.1128/aac.00952-09
Streptococcus Streptococcus EC50 60.0 nM None
Streptococcus Streptococcus MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC 0.015 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC 0.03 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC 0.031 ug.mL-1 10.1016/j.ejmech.2011.07.042
Streptococcus Streptococcus MIC50 0.015 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC50 0.06 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC90 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
Streptococcus Streptococcus MIC90 0.06 ug.mL-1 10.1128/aac.01453-08
Streptococcus Streptococcus MIC90 1.0 ug.mL-1 10.1128/aac.01453-08
Streptococcus agalactiae Streptococcus agalactiae Activity 0.0 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae Activity 95.2 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae Activity 96.0 % 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae Activity 100.0 % 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae Activity 100.0 % 10.1128/aac.00400-09
Streptococcus agalactiae Streptococcus agalactiae Activity 100.0 % 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae Activity nan None 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae MIC 0.016 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus agalactiae Streptococcus agalactiae MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.25 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 0.5 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 1.0 ug.mL-1 10.1128/aac.00185-08
Streptococcus agalactiae Streptococcus agalactiae MIC 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.00400-09
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.063 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC50 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.00336-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.063 ug.mL-1 10.1128/aac.01716-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus agalactiae Streptococcus agalactiae MIC90 0.25 ug.mL-1 10.1128/aac.00400-09
Streptococcus agalactiae Streptococcus agalactiae MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus agalactiae Streptococcus agalactiae MIC95 0.03 ug ml-1 10.1128/aac.00400-09
Streptococcus constellatus Streptococcus constellatus Activity 53.2 % 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus Activity 62.0 % 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus constellatus Streptococcus constellatus MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus constellatus Streptococcus constellatus MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus constellatus Streptococcus constellatus MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus constellatus Streptococcus constellatus MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC50 nan None 10.1128/aac.01398-07
Streptococcus constellatus Streptococcus constellatus MIC90 0.12 ug.mL-1 10.1128/aac.00336-08
Streptococcus constellatus Streptococcus constellatus MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus constellatus Streptococcus constellatus MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus constellatus Streptococcus constellatus MIC90 nan None 10.1128/aac.01398-07
Streptococcus equinus Streptococcus equinus Activity 53.2 % 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus equinus Streptococcus equinus MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus equinus Streptococcus equinus MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus equinus Streptococcus equinus MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus equinus Streptococcus equinus MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus gordonii Streptococcus gordonii Activity 0.6 log10CFU/ml 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii Activity 0.7 log10CFU/ml 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii Activity 0.7 None 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii Activity 1.39 None 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii Activity 1.55 None 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii Activity 2.0 log10CFU/ml 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Activity 2.1 None 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii Activity 3.9 log10CFU/ml 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii Activity 4.0 log10CFU/ml 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Activity 4.5 log10CFU/ml 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii Activity 45.0 min 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Activity 48.4 min 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Activity 60.6 min 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Activity nan None 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii Activity nan None 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Activity nan None 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii Inhibition nan % 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii MIC 0.008 ug.mL-1 10.1128/aac.00699-09
Streptococcus gordonii Streptococcus gordonii MIC 0.008 ug.mL-1 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii MIC 0.008 ug.mL-1 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii MIC 0.5 ug.mL-1 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii MIC 2.0 ug.mL-1 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii MIC 2.0 ug.mL-1 10.1128/aac.01127-06
Streptococcus gordonii Streptococcus gordonii Ratio 0.8 None 10.1128/aac.00939-07
Streptococcus gordonii Streptococcus gordonii Ratio 1.06 None 10.1128/aac.00939-07
Streptococcus intermedius Streptococcus intermedius Activity 53.2 % 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius Activity 62.0 % 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus intermedius Streptococcus intermedius MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus intermedius Streptococcus intermedius MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC50 nan None 10.1128/aac.01398-07
Streptococcus intermedius Streptococcus intermedius MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus intermedius Streptococcus intermedius MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus intermedius Streptococcus intermedius MIC90 nan None 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis Activity 53.2 % 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis Activity 62.0 % 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus mitis Streptococcus mitis MIC 0.25 ug.mL-1 10.1128/aac.00336-08
Streptococcus mitis Streptococcus mitis MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus mitis Streptococcus mitis MIC50 0.5 ug.mL-1 10.1128/aac.00336-08
Streptococcus mitis Streptococcus mitis MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC50 nan None 10.1128/aac.01398-07
Streptococcus mitis Streptococcus mitis MIC90 0.5 ug.mL-1 10.1128/aac.00336-08
Streptococcus mitis Streptococcus mitis MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus mitis Streptococcus mitis MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus mitis Streptococcus mitis MIC90 nan None 10.1128/aac.01398-07
Streptococcus mutans Streptococcus mutans GI nan None 10.1021/np2004775
Streptococcus mutans Streptococcus mutans MBC 1.56 ug ml-1 10.1021/np400788r
Streptococcus mutans Streptococcus mutans MBC 4.7 uM 10.1021/acs.jnatprod.6b00831
Streptococcus mutans Streptococcus mutans MIC 0.049 ug.mL-1 10.1021/np50088a008
Streptococcus mutans Streptococcus mutans MIC 0.05 ug.mL-1 10.1021/np400788r
Streptococcus mutans Streptococcus mutans MIC 1.1 ug.mL-1 10.1021/acs.jnatprod.9b00315
Streptococcus mutans Streptococcus mutans MIC 150.0 nM 10.1021/acs.jnatprod.6b00831
Streptococcus oralis Streptococcus oralis Activity 53.2 % 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis Activity 62.0 % 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus oralis Streptococcus oralis MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus oralis Streptococcus oralis MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC50 nan None 10.1128/aac.01398-07
Streptococcus oralis Streptococcus oralis MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus oralis Streptococcus oralis MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus oralis Streptococcus oralis MIC90 nan None 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.0 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 0.9 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 5.0 % 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 6.8 % 10.1128/aac.01388-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 11.4 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 14.7 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 14.9 % 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 15.7 % 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 16.8 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 24.5 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 31.3 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 35.5 % 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 37.9 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 38.4 % 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 41.7 % 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 44.5 % 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 46.6 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 46.7 % 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 64.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 68.6 % 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 71.5 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 74.0 % 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae Activity 76.4 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 77.1 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 79.3 % 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 85.7 % 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae Activity 93.5 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 94.1 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 98.3 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 99.8 % 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae Activity 100.0 % 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.0078 ug.mL-1 10.1016/j.ejmech.2016.12.054
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.008 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.01 ug.mL-1 10.1038/nchembio.2007.21
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.0125 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1021/np400759f
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.015 ug.mL-1 10.1128/aac.01326-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.016 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.02 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.025 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01383-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.03 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.035 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.04 ug.mL-1 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.05 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.01.075
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.05.061
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1016/j.bmcl.2009.06.077
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.063 ug.mL-1 10.1016/j.ejmech.2019.111744
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.1 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01326-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.12 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.125 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.19 ug.mL-1 10.1021/jm900625q
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.2 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.00185-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01383-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.25 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 0.5 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmc.2020.115776
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01383-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.5 ug.mL-1 10.1038/nchembio.2007.21
Streptococcus pneumoniae Streptococcus pneumoniae MIC 1.6 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1038/nchembio.2007.21
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 2.0 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 3.2 ug.mL-1 10.1128/aac.01655-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1021/jm020328y
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1021/jm900625q
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01066-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01383-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01464-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 4.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 6.0 ug.mL-1 10.1038/nchembio.2007.21
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01082-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01383-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 8.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.00019-10
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 16.0 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC 32.0 ug.mL-1 10.1128/aac.00026-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1016/j.bmcl.2010.11.102
Streptococcus pneumoniae Streptococcus pneumoniae MIC 383230.0 nM 10.1016/j.ejmech.2019.01.038
Streptococcus pneumoniae Streptococcus pneumoniae MIC nan None 10.1016/j.bmc.2007.08.035
Streptococcus pneumoniae Streptococcus pneumoniae MIC nan None 10.1128/aac.01107-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC nan None 10.1128/aac.01383-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01326-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.016 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.03 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.12 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.125 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.25 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 0.5 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 1.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1016/j.bmc.2020.115776
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1021/jm1014023
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01017-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01326-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 4.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC50 25.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC80 2.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.015 ug.mL-1 10.1128/aac.01326-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.03 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.125 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.00400-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.25 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 0.5 ug.mL-1 10.1128/aac.01548-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 1.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1021/jm301650g
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00046-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01332-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01374-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01384-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01398-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 2.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1016/j.bmc.2020.115776
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.00952-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01017-06
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01229-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01268-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01326-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01387-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01487-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01531-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01620-07
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 4.0 ug.mL-1 10.1128/aac.01797-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 7.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1021/jm1014023
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.00712-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 8.0 ug.mL-1 10.1128/aac.01324-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 13.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 16.0 ug.mL-1 10.1128/aac.01123-09
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 23.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 33.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 50.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 57.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 67.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 92.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae MIC90 100.0 ug.mL-1 10.1128/aac.00310-08
Streptococcus pneumoniae Streptococcus pneumoniae Ratio 150.0 None 10.1038/nchembio.2007.21
Streptococcus pneumoniae R6 Penicillin-binding protein 2X Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.002 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.008 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.009 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.012 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.016 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.02 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 1A IC50 0.031 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.007 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.008 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.037 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.06 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.061 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.096 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.111 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.15 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.156 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.178 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2B IC50 0.264 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x Activity nan None 10.1021/jm900625q
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.007 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.008 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.009 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.01 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.011 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.028 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.041 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x IC50 0.642 ug.mL-1 10.1128/aac.01566-08
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Penicillin-binding protein 2x Inhibition 5.0 % 10.1016/j.ejmech.2008.10.016
Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Penicillin-binding protein 2B IC50 0.8 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Penicillin-binding protein 2B IC50 1.8 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Penicillin-binding protein 2B IC50 2.5 ug.mL-1 10.1128/aac.00590-10
Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Penicillin-binding protein 2B IC50 8.0 ug.mL-1 10.1128/aac.00590-10
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 0.0 % 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes Activity 16.0 % 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes Activity 93.0 % 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes Activity 98.9 % 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.00400-09
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes Activity 100.0 % 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes IZ 0.0 mm 10.1016/j.ejmech.2017.11.001
Streptococcus pyogenes Streptococcus pyogenes MIC 0.0078 ug.mL-1 10.1016/j.ejmech.2016.12.054
Streptococcus pyogenes Streptococcus pyogenes MIC 0.01 ug.mL-1 10.1021/jm00142a024
Streptococcus pyogenes Streptococcus pyogenes MIC 0.012 ug.mL-1 10.1128/aac.00604-06
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.015 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.03 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus pyogenes Streptococcus pyogenes MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC 0.39 ug.mL-1 10.1021/jm00346a024
Streptococcus pyogenes Streptococcus pyogenes MIC 1.0 ug.mL-1 10.1016/j.bmcl.2015.07.044
Streptococcus pyogenes Streptococcus pyogenes MIC 383230.0 nM 10.1016/j.ejmech.2019.01.038
Streptococcus pyogenes Streptococcus pyogenes MIC nan ug.mL-1 10.1016/s0960-894x(99)00127-4
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.00400-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.03 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus pyogenes Streptococcus pyogenes MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1128/aac.00418-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.015 ug.mL-1 10.1128/aac.01548-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.00336-08
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.00400-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.00952-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.01123-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.03 ug.mL-1 10.1128/aac.01536-09
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus pyogenes Streptococcus pyogenes MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus pyogenes Streptococcus pyogenes MIC95 0.03 ug ml-1 10.1128/aac.00400-09
Streptococcus pyogenes serotype M1 Streptokinase A EC50 60.0 nM None
Streptococcus salivarius Streptococcus salivarius Activity 53.2 % 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus salivarius Streptococcus salivarius MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis Activity 53.2 % 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus sanguinis Streptococcus sanguinis MIC 0.5 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus sanguinis Streptococcus sanguinis MIC50 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sanguinis Streptococcus sanguinis MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus sanguinis Streptococcus sanguinis MIC90 32.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sobrinus Streptococcus sobrinus GI nan None 10.1021/np2004775
Streptococcus sp. Streptococcus sp. Activity nan None 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus sp. Streptococcus sp. MIC 2.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus sp. Streptococcus sp. MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. Streptococcus sp. MIC90 0.06 ug.mL-1 10.1128/aac.01641-07
Streptococcus sp. Streptococcus sp. MIC90 1.0 ug.mL-1 10.1128/aac.01641-07
Streptococcus sp. Streptococcus sp. MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' Activity 100.0 % 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' Activity nan None 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' EC50 60.0 nM None
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC 0.06 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC50 0.06 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group A' Streptococcus sp. 'group A' MIC90 0.06 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' Activity 100.0 % 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' Activity nan None 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.015 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.03 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.06 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.06 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.06 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.12 ug.mL-1 10.1128/aac.00461-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.25 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 0.5 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC 1.0 ug.mL-1 10.1128/aac.00596-08
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC50 0.06 ug.mL-1 10.1128/aac.00129-09
Streptococcus sp. 'group B' Streptococcus sp. 'group B' MIC90 0.06 ug.mL-1 10.1128/aac.00129-09
Streptococcus viridans Streptococcus viridans Activity 0.0 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 28.6 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans Activity 62.0 % 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans Activity 100.0 % 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.06 ug.mL-1 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans MIC 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC 0.25 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 0.5 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC50 nan None 10.1128/aac.01398-07
Streptococcus viridans Streptococcus viridans MIC90 0.12 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC90 8.0 ug.mL-1 10.1128/aac.00149-08
Streptococcus viridans Streptococcus viridans MIC90 nan None 10.1128/aac.01398-07
Trichoderma harzianum Trichoderma harzianum MIC 100.0 ug.mL-1 10.1021/np0602057
Veillonella parvula Veillonella parvula MIC 0.06 ug.mL-1 10.1128/aac.00355-08
Xanthomonas campestris Xanthomonas campestris IZ 12.0 mm 10.1016/j.bmcl.2012.05.001
Xanthomonas vesicatoria Xanthomonas vesicatoria MIC 250.0 ug.mL-1 10.1016/j.bmcl.2016.06.015
Yarrowia lipolytica Yarrowia lipolytica MIC 100.0 ug.mL-1 10.1021/np0602057
Yersinia enterocolitica Yersinia enterocolitica MIC 1.0 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 4.0 ug.mL-1 10.1128/aac.01754-09
Yersinia enterocolitica Yersinia enterocolitica MIC 24.0 ug.mL-1 10.1128/aac.01754-09
Zymoseptoria tritici Zymoseptoria tritici IZ 12.0 mm 10.1021/np200330c
Zymoseptoria tritici Zymoseptoria tritici IZ nan None 10.1021/np300475d
None ADMET Activity nan None 10.1016/j.ejmech.2007.10.007
None ADMET Activity nan None 10.1016/j.ejmech.2010.01.050
None ADMET CC50 228900.0 nM 10.1016/j.ejmech.2013.11.020
None ADMET CL 6.9 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET Drug metabolism nan None 10.1039/C5MD00325C
None ADMET LC30 10.0 ug ml-1 10.1016/j.bmc.2014.09.048
None ADMET MRT 0.58 hr 10.1124/dmd.108.020479
None ADMET PPB 60.0 % 10.1016/j.ejmech.2020.112829
None ADMET RVmax 1.0 None 10.1021/jm00369a001
None ADMET T1/2 0.4167 hr 10.1016/S0960-894X(01)80141-4
None ADMET T1/2 0.7 hr 10.1124/dmd.108.020479
None ADMET Vdss 0.24 L.kg-1 10.1124/dmd.108.020479
None Erythrocyte Activity nan None 10.1016/j.ejmech.2017.11.052
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None NON-PROTEIN TARGET Activity 0.0 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity 53.2 % 10.1128/aac.00418-09
None NON-PROTEIN TARGET Activity 100.0 % 10.1128/aac.00952-09
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00418-09
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00729-05
None NON-PROTEIN TARGET Fu 0.4 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 3.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 9.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 13.2 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 185720.0 nM 10.1016/j.bmc.2014.09.048
None NON-PROTEIN TARGET IZ 15.0 mm 10.1007/s00044-013-0837-4
None NON-PROTEIN TARGET MBC 6.25 mg/ml 10.1128/aac.00788-09
None NON-PROTEIN TARGET MIC 0.015 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC 0.015 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 0.016 U/ml 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.023 ug.mL-1 10.1128/aac.00684-07
None NON-PROTEIN TARGET MIC 0.03 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC 0.03 U/ml 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.032 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 0.06 ug.mL-1 10.1128/aac.01641-07
None NON-PROTEIN TARGET MIC 0.06 U/ml 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.125 U/ml 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.128 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 0.25 U/ml 10.1128/aac.00044-08
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 0.98 ug.mL-1 10.1128/aac.00261-06
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00684-07
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.00915-09
None NON-PROTEIN TARGET MIC 3.12 ug.mL-1 10.1021/jm00346a024
None NON-PROTEIN TARGET MIC 12.5 ug.mL-1 10.1016/j.bmcl.2004.12.020
None NON-PROTEIN TARGET MIC 24.0 ug.mL-1 10.1128/aac.00788-09
None NON-PROTEIN TARGET MIC 500.0 ug.mL-1 10.1016/j.bmcl.2010.12.084
None NON-PROTEIN TARGET MIC50 0.03 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC50 0.06 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC50 0.06 ug.mL-1 10.1128/aac.01641-07
None NON-PROTEIN TARGET MIC50 8.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC90 0.03 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 0.03 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC90 0.06 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 0.06 ug.mL-1 10.1128/aac.00952-09
None NON-PROTEIN TARGET MIC90 0.06 ug.mL-1 10.1128/aac.01641-07
None NON-PROTEIN TARGET MIC90 1.0 ug.mL-1 10.1128/aac.00336-08
None NON-PROTEIN TARGET MIC90 1.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MIC90 16.0 ug.mL-1 10.1128/aac.00418-09
None NON-PROTEIN TARGET MPC 23.56 ug ml-1 10.1021/jm000213z
None NON-PROTEIN TARGET MPC 28.84 ug ml-1 10.1021/jm000213z
None No relevant target LogP 1.76 None 10.1021/jm00128a019
None No relevant target pKa 2.6 None 10.1021/jm00128a019
None No relevant target pKa 2.72 None 10.1007/s11095-013-1232-z
None No relevant target pKa 2.8 None 10.1016/j.ejmech.2009.06.004
None No relevant target pKa_A1 3.32 None 10.6019/CHEMBL3301361
None Nucleic Acid BPR 67.2 None 10.1124/dmd.111.041145
None Osteoblast Activity nan None 10.1128/aac.00729-05
None Unchecked Activity 5.0 U 10.1128/aac.01304-07
None Unchecked Activity 100.0 % 10.1128/aac.00083-07
None Unchecked Activity 130.0 % 10.1128/aac.00175-08
None Unchecked Activity 150.0 mU 10.1128/aac.00978-07
None Unchecked Activity 160.0 % 10.1128/aac.01004-09
None Unchecked Activity 170.0 mU 10.1128/aac.00978-07
None Unchecked Activity 210.0 % 10.1128/aac.00218-07
None Unchecked Activity 210.0 % 10.1128/aac.01004-09
None Unchecked Activity 210.0 mU 10.1128/aac.00978-07
None Unchecked Activity 220.0 mU 10.1128/aac.00978-07
None Unchecked Activity 260.0 % 10.1128/aac.00175-08
None Unchecked Activity 420.0 % 10.1128/aac.00175-08
None Unchecked Activity 440.0 % 10.1128/aac.01004-09
None Unchecked Activity 800.0 % 10.1128/aac.00175-08
None Unchecked Activity 2700.0 % 10.1128/aac.00218-07
None Unchecked Activity 2700.0 % 10.1128/aac.01004-09
None Unchecked Activity nan None 10.1128/aac.00978-07
None Unchecked Concentration 0.1 ug ml-1 10.1016/S0960-894X(01)80948-3
None Unchecked Concentration 2.0 ug ml-1 10.1016/S0960-894X(01)80948-3
None Unchecked Concentration 10.0 ug ml-1 10.1016/S0960-894X(01)80948-3
None Unchecked Concentration 100.0 ug ml-1 10.1016/S0960-894X(01)80948-3
None Unchecked FC 10.0 None 10.1128/aac.00537-07
None Unchecked Hepatotoxicity (acute) 17.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 9.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 5.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.001 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.004 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.005 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.007 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.009 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.01 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.011 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.013 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.014 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.015 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.016 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.02 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.021 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.023 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.029 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.03 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.06 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 0.1 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 0.133 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.205 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.248 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.25 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.323 ug.mL-1 10.1128/aac.01566-08
None Unchecked IC50 0.5 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 0.6 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 0.9 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 1.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 1.3 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 1.5 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 1.6 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 2.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 2.0 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 4.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 6.0 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 8.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 8.0 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 10.0 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 55.0 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 64.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 75.0 ug.mL-1 10.1128/aac.00983-09
None Unchecked IC50 80.0 nM 10.1128/aac.01082-06
None Unchecked IC50 128.0 ug.mL-1 10.1128/aac.00019-10
None Unchecked IC50 4900.0 nM 10.1016/j.ejmech.2013.11.020
None Unchecked IC50 nan None 10.1128/aac.00019-10
None Unchecked IC50 nan None 10.1128/aac.01566-08
None Unchecked IC50 nan None None
None Unchecked INH 15.0 /M/s 10.1128/aac.00983-09
None Unchecked Inhibition 10.0 % 10.1016/j.ejmech.2008.10.016
None Unchecked Kcat 0.1 /s 10.1128/aac.01463-07
None Unchecked Kcat 2.0 /s 10.1128/aac.01062-07
None Unchecked Kcat 3.5 /s 10.1128/aac.01028-07
None Unchecked Kcat 5.0 /s 10.1128/aac.00856-09
None Unchecked Kcat 5.0 /s 10.1128/aac.01252-09
None Unchecked Kcat 5.75 /s 10.1128/aac.00771-10
None Unchecked Kcat 10.0 /s 10.1128/aac.01284-08
None Unchecked Kcat 10.5 /s 10.1128/aac.01028-07
None Unchecked Kcat 10.92 /s 10.1128/aac.00083-07
None Unchecked Kcat 13.5 /s 10.1128/aac.00771-10
None Unchecked Kcat 14.2 /s 10.1128/aac.00771-10
None Unchecked Kcat 23.0 /s 10.1128/aac.00219-09
None Unchecked Kcat 23.0 /s 10.1128/aac.01337-07
None Unchecked Kcat 24.0 /s 10.1128/aac.00219-09
None Unchecked Kcat 27.0 /s 10.1128/aac.01252-09
None Unchecked Kcat 27.2 /s 10.1128/aac.00771-10
None Unchecked Kcat 28.6 /s 10.1128/aac.00771-10
None Unchecked Kcat 30.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 30.0 /s 10.1128/aac.00166-08
None Unchecked Kcat 30.5 /s 10.1128/aac.00771-10
None Unchecked Kcat 31.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 31.0 /s 10.1128/aac.00961-09
None Unchecked Kcat 35.0 /s 10.1128/aac.01410-08
None Unchecked Kcat 37.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 38.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 45.0 /s 10.1128/aac.00163-08
None Unchecked Kcat 45.0 /s 10.1128/aac.01252-09
None Unchecked Kcat 51.0 /s 10.1128/aac.01028-07
None Unchecked Kcat 54.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 54.0 /s 10.1128/aac.00858-10
None Unchecked Kcat 56.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 60.0 /s 10.1128/aac.00387-08
None Unchecked Kcat 64.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 76.0 /s 10.1128/aac.00218-07
None Unchecked Kcat 76.0 /s 10.1128/aac.01004-09
None Unchecked Kcat 80.0 /s 10.1128/aac.00614-07
None Unchecked Kcat 150.0 /s 10.1128/aac.01600-06
None Unchecked Kcat 178.0 /s 10.1128/aac.01145-07
None Unchecked Kcat 196.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 206.0 /s 10.1128/aac.00017-09
None Unchecked Kcat 230.0 /s 10.1128/aac.00175-08
None Unchecked Kcat 235.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 240.0 /s 10.1128/aac.00175-08
None Unchecked Kcat 243.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 251.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 280.0 /s 10.1128/aac.00098-10
None Unchecked Kcat 320.0 /s 10.1128/aac.00774-09
None Unchecked Kcat 320.0 /s 10.1128/aac.00858-10
None Unchecked Kcat 611.0 /s 10.1128/aac.01442-09
None Unchecked Kcat 800.0 /s 10.1128/aac.01004-09
None Unchecked Kcat 800.0 /s 10.1128/aac.01058-06
None Unchecked Kcat 830.0 /s 10.1128/aac.00684-07
None Unchecked Kcat 1050.0 /s 10.1128/aac.00614-07
None Unchecked Kcat 1500.0 /s 10.1128/aac.01058-06
None Unchecked Kcat/Km 0.036 /uM/s 10.1128/aac.00166-08
None Unchecked Kcat/Km 0.063 /s/microM 10.1128/aac.00856-09
None Unchecked Kcat/Km 0.07 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.1 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.26 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.32 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.36 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.42 /uM/s 10.1128/aac.00771-10
None Unchecked Kcat/Km 0.51 /s/microM 10.1128/aac.00175-08
None Unchecked Kcat/Km 0.62 /s/microM 10.1128/aac.00774-09
None Unchecked Kcat/Km 0.84 /uM/s 10.1128/aac.00083-07
None Unchecked Kcat/Km 1.0 10'7/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 1.0 /s/M 10.1128/aac.01025-07
None Unchecked Kcat/Km 1.1 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 1.3 10'5/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 1.3 /uM/s 10.1128/aac.00050-10
None Unchecked Kcat/Km 1.4 10'7/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 1.7 10'4/M/s 10.1128/aac.01337-07
None Unchecked Kcat/Km 1.8 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 2.2 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 2.3 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 2.9 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 3.5 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 3.6 /s/microM 10.1128/aac.00017-09
None Unchecked Kcat/Km 5.7 10'5/M/s 10.1128/aac.01252-09
None Unchecked Kcat/Km 5.8 /uM/s 10.1128/aac.01028-07
None Unchecked Kcat/Km 6.1 10'6/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 6.2 10'5/M/s 10.1128/aac.00858-10
None Unchecked Kcat/Km 7.4 10'5/s/M 10.1128/aac.00098-10
None Unchecked Kcat/Km 7.5 None 10.1128/aac.00614-07
None Unchecked Kcat/Km 8.3 10'7/M/s 10.1128/aac.00684-07
None Unchecked Kcat/Km 9.2 10'3/M/s 10.1128/aac.01062-07
None Unchecked Kcat/Km 9.5 /uM/s 10.1128/aac.01442-09
None Unchecked Kcat/Km 9.6 /s/microM 10.1128/aac.00175-08
None Unchecked Kcat/Km 10.0 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 11.0 None 10.1128/aac.00614-07
None Unchecked Kcat/Km 13.0 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 13.3 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 14.3 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 15.0 /s/microM 10.1128/aac.00218-07
None Unchecked Kcat/Km 15.0 /s/microM 10.1128/aac.01004-09
None Unchecked Kcat/Km 15.0 /uM/s 10.1128/aac.01028-07
None Unchecked Kcat/Km 19.6 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 20.0 /s/microM 10.1128/aac.01004-09
None Unchecked Kcat/Km 25.0 /uM/s 10.1128/aac.01284-08
None Unchecked Kcat/Km 25.5 /uM/s 10.1128/aac.01028-07
None Unchecked Kcat/Km 38.0 /uM/s 10.1128/aac.00219-09
None Unchecked Kcat/Km 40.0 /uM/s 10.1128/aac.00219-09
None Unchecked Kcat/Km 44.0 /uM/s 10.1128/aac.01058-06
None Unchecked Kcat/Km 120.0 /uM/s 10.1128/aac.01585-09
None Unchecked Kcat/Km 1000.0 /mM/s 10.1128/aac.00961-09
None Unchecked Kcat/Km 1000.0 /uM/s 10.1128/aac.00163-08
None Unchecked Kcat/Km 1200.0 /uM/s 10.1128/aac.01410-08
None Unchecked Kcat/Km 1500.0 /uM/s 10.1128/aac.00387-08
None Unchecked Kcat/Km 6600.0 /mM/s 10.1128/aac.01145-07
None Unchecked Kcat/Km 10000.0 /mM/s 10.1128/aac.01082-06
None Unchecked Ki 600.0 nM 10.1128/aac.00219-09
None Unchecked Ki 2000.0 nM 10.1128/aac.01252-09
None Unchecked Ki nan None None
None Unchecked Kic nan None 10.1016/j.bmcl.2012.01.123
None Unchecked Kiuc nan None 10.1016/j.bmcl.2012.01.123
None Unchecked Km 7.0 /s/microM 10.1128/aac.00614-07
None Unchecked Km 140.0 /s/microM 10.1128/aac.00614-07
None Unchecked Km 400.0 nM 10.1128/aac.01284-08
None Unchecked Km 600.0 nM 10.1128/aac.00219-09
None Unchecked Km 600.0 nM 10.1128/aac.01028-07
None Unchecked Km 700.0 nM 10.1128/aac.01028-07
None Unchecked Km 2000.0 nM 10.1128/aac.01028-07
None Unchecked Km 4400.0 nM 10.1128/aac.01252-09
None Unchecked Km 5000.0 nM 10.1128/aac.00218-07
None Unchecked Km 5000.0 nM 10.1128/aac.01004-09
None Unchecked Km 8700.0 nM 10.1128/aac.01252-09
None Unchecked Km 10000.0 nM 10.1128/aac.00684-07
None Unchecked Km 10000.0 nM 10.1128/aac.01463-07
None Unchecked Km 12000.0 nM 10.1128/aac.01058-06
None Unchecked Km 13000.0 nM 10.1128/aac.00083-07
None Unchecked Km 15000.0 nM 10.1128/aac.01058-06
None Unchecked Km 16000.0 nM 10.1128/aac.00098-10
None Unchecked Km 17000.0 nM 10.1128/aac.00098-10
None Unchecked Km 17000.0 nM 10.1128/aac.01058-06
None Unchecked Km 20000.0 nM 10.1128/aac.01082-06
None Unchecked Km 20000.0 nM 10.1128/aac.01600-06
None Unchecked Km 22000.0 nM 10.1128/aac.00098-10
None Unchecked Km 25000.0 nM 10.1128/aac.00098-10
None Unchecked Km 25000.0 nM 10.1128/aac.00175-08
None Unchecked Km 25000.0 nM 10.1128/aac.01058-06
None Unchecked Km 27000.0 nM 10.1128/aac.01145-07
None Unchecked Km 29000.0 nM 10.1128/aac.00098-10
None Unchecked Km 30000.0 nM 10.1128/aac.01410-08
None Unchecked Km 34000.0 nM 10.1128/aac.01058-06
None Unchecked Km 39000.0 nM 10.1128/aac.00771-10
None Unchecked Km 40000.0 nM 10.1128/aac.00387-08
None Unchecked Km 40000.0 nM 10.1128/aac.01004-09
None Unchecked Km 44000.0 nM 10.1128/aac.00163-08
None Unchecked Km 46000.0 nM 10.1128/aac.00098-10
None Unchecked Km 48000.0 nM 10.1128/aac.00961-09
None Unchecked Km 51000.0 nM 10.1128/aac.00098-10
None Unchecked Km 60000.0 nM 10.1128/aac.01058-06
None Unchecked Km 64000.0 nM 10.1128/aac.01442-09
None Unchecked Km 64200.0 nM 10.1128/aac.00771-10
None Unchecked Km 80000.0 nM 10.1128/aac.00856-09
None Unchecked Km 87600.0 nM 10.1128/aac.00771-10
None Unchecked Km 88900.0 nM 10.1128/aac.00771-10
None Unchecked Km 90000.0 nM 10.1128/aac.00858-10
None Unchecked Km 120000.0 nM 10.1128/aac.00771-10
None Unchecked Km 139000.0 nM 10.1128/aac.00771-10
None Unchecked Km 200000.0 nM 10.1128/aac.01062-07
None Unchecked Km 450000.0 nM 10.1128/aac.00175-08
None Unchecked Km 520000.0 nM 10.1128/aac.00774-09
None Unchecked Km 520000.0 nM 10.1128/aac.00858-10
None Unchecked Km 840000.0 nM 10.1128/aac.00166-08
None Unchecked Km 1340000.0 nM 10.1128/aac.01337-07
None Unchecked Km nan None 10.1128/aac.00389-07
None Unchecked MIC 0.05 ug.mL-1 10.1021/jm00126a041
None Unchecked MIC 71.0 ug.mL-1 10.1021/jm00126a041
None Unchecked MIC 128.0 ug.mL-1 10.1021/jm000213z
None Unchecked MIC 200.0 ug.mL-1 10.1021/jm00126a041
None Unchecked Potency 4610.9 nM None
None Unchecked Ratio 8.0 None 10.1128/aac.00614-07
None Unchecked Ratio 10.0 None 10.1128/aac.01463-07
None Unchecked Ratio 200.0 None 10.1128/aac.00537-07
None Unchecked Ratio 7500.0 /mM/s 10.1128/aac.01600-06
None Unchecked Selectivity Index 10.2 None 10.1016/j.bmc.2014.05.064
None Unchecked Selectivity Index 10204.0 None 10.1016/j.bmc.2014.12.019
None Unchecked T1/2 0.3333 hr 10.1016/j.ejmech.2020.112829
None Unchecked Vmax nan None 10.1128/aac.00389-07
None Unchecked Vmax/Km nan None 10.1128/aac.00389-07

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT006860 CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O.O=C(O)CNC(=O)Cc1ccccc1>>CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O enzymemap_76133
AKRT006862 CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O.O=C(O)Cc1ccccc1>>CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O enzymemap_76104
AKRT006863 CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O.O=C([CoA])Cc1ccccc1>>CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O RXN-17062
AKRT006875 CC1(C)S[C@@H]2[C@H](NC(=O)CCC[C@H](N)C(=O)O)C(=O)N2[C@H]1C(=O)O.O=C([CoA])Cc1ccccc1>>CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O 2.3.1.164-RXN
AKRT006883 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O.NCC(=O)O>>O=C(O)CNC(=O)Cc1ccccc1 enzymemap_76133
AKRT006884 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O.O=C(O)COc1ccccc1>>CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O RXN-17100
AKRT006885 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O>>CC(=O)Oc1ccccc1 MNXR145936
AKRT006886 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O>>CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O MNXR145936
AKRT006887 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O>>CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O.O=C(O)Cc1ccccc1 None
AKRT006888 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O>>CC1(C)[C@H](C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3ccccc3)[C@H]2[S@@]1=O enzymemap_9033
AKRT006889 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O>>CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3ccccc3)[C@H]2SC1 enzymemap_15382
AKRT006890 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O>>O=C(O)Cc1ccccc1 RXN-17100
AKRT023457 O=C([CoA])Cc1ccccc1.CC1(C)S[C@@H]2[C@H](NC(=O)CCC[C@H](N)C(=O)O)C(=O)N2[C@H]1C(=O)O>>CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O enzymemap_29086