Biscryptolepine
AlkaPlorer ID: AK003695
Synonym: None
IUPAC Name: 5-methyl-11-(5-methylindolo[3,2-b]quinolin-11-yl)indolo[3,2-b]quinoline
Structure
SMILES: CN1C2=C3C=CC=CC3=NC2=C(C2=C3N=C4C=CC=CC4=C3N(C)C3=CC=CC=C23)C2=CC=CC=C21
InChI: InChI=1S/C32H22N4/c1-35-25-17-9-5-13-21(25)27(29-31(35)19-11-3-7-15-23(19)33-29)28-22-14-6-10-18-26(22)36(2)32-20-12-4-8-16-24(20)34-30(28)32/h3-18H,1-2H3
InChIKey: GPXBTNAIIIXHOX-UHFFFAOYSA-N
Reference
PubChem CID: 10457065
CAS: 175178-79-7
LOTUS: LTS0089992
SuperNatural Ⅲ: SN0112222
COCONUT: CNP0153452
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Cryptolepis sanguinolenta | Cryptolepis | Apocynaceae | Gentianales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 462.55600000000015
TPSA？: 35.64
MolLogP？: 7.643000000000006
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 8
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania donovani | Leishmania donovani | IC50 | 8930.0 | nM | 10.1021/np0496284 |
| Mycolicibacterium fortuitum | Mycolicibacterium fortuitum | MIC | 6.25 | ug.mL-1 | 10.1016/j.ejmech.2017.06.005 |
| Mycolicibacterium fortuitum | Mycolicibacterium fortuitum | MIC | 6.25 | ug.mL-1 | 10.1016/j.ejmech.2022.114173 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 270.0 | nM | 10.1021/np0496284 |
| Rattus norvegicus | L6 | IC50 | 13620.0 | nM | 10.1021/np0496284 |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 2570.0 | nM | 10.1021/np0496284 |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 3480.0 | nM | 10.1021/np0496284 |