10125-07-2
AlkaPlorer ID: AK003724
Synonym: '23927-19-7', '(S)-3-Benzylpiperazine-2,5-dione', '5037-75-2'
IUPAC Name: (3S)-3-benzylpiperazine-2,5-dione
Structure
SMILES: OC1=N[C@@H](CC2=CC=CC=C2)C(O)=NC1
InChI: InChI=1S/C11H12N2O2/c14-10-7-12-11(15)9(13-10)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,15)(H,13,14)/t9-/m0/s1
InChIKey: UZOJHXFWJFSFAI-VIFPVBQESA-N
Reference
α-Glucosidase inhibitors and phytotoxins from <i>Streptomyces xanthophaeus</i>
PubChem CID: 7076549
CAS: 10125-07-2
LOTUS: LTS0134664
SuperNatural Ⅲ: SN0384372-02
NPASS: NPC226438
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Aspergillus fumigatus | Aspergillus | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 204.229
TPSA？: 65.18
MolLogP？: 1.5243
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Artemia salina | Artemia salina | LC50 | 100.0 | ug.mL-1 | 10.1021/jf300146n |
| Fusobacterium nucleatum | Fusobacterium nucleatum | Inhibition | nan | % | 10.1016/j.bmc.2018.11.042 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | Km | 90900.0 | nM | 10.1211/002235702320402152 |
| Plasmodium berghei | Plasmodium berghei | Activity | 70.37 | % | 10.1016/j.bmcl.2012.09.094 |
| Plasmodium berghei | Plasmodium berghei | IC50 | 4260.0 | nM | 10.1016/j.bmcl.2012.09.094 |
| Porphyromonas gingivalis | Porphyromonas gingivalis | Inhibition | nan | % | 10.1016/j.bmc.2018.11.042 |
| Streptococcus mutans | Streptococcus mutans | GI | nan | None | 10.1016/j.bmc.2018.11.042 |
| Streptococcus mutans | Streptococcus mutans | Inhibition | nan | % | 10.1016/j.bmc.2018.11.042 |