Molecule

Camptothecin

AlkaPlorer ID: AK004080

Synonym: None

IUPAC Name: (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

Structure

SMILES: CC[C@@]1(O)C(=O)OCC2=C1C=C1C3=NC4=CC=CC=C4C=C3CN1C2=O

InChI: InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1

InChIKey: VSJKWCGYPAHWDS-FQEVSTJZSA-N

Reference

Camptothecin Biosynthetic Genes in Hairy Roots of Ophiorrhiza pumila: Cloning, Characterization and Differential Expression in Tissues and by Stress Compounds

PubChem CID: 24360

CAS: 7689-03-4

LOTUS: LTS0270094

SuperNatural Ⅲ: SN0398798-01

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Ophiorrhiza kuroiwae	Ophiorrhiza	Rubiaceae	Gentianales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 348.3580000000001

TPSA？: 81.41999999999999

MolLogP？: 2.0796

Number of H-Donors: 1

Number of H-Acceptors: 6

RingCount: 5

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Acinetobacter baumannii	Acinetobacter baumannii	Inhibition	-0.94	%	10.6019/CHEMBL4296183
Agrobacterium tumefaciens	Agrobacterium tumefaciens	Activity	-100.0	%	10.1021/np50107a012
Artemia	Artemia	LC50	nan	None	10.1021/np0496587
Aspergillus niger	Aspergillus niger	IZ	nan	None	10.1021/np010459m
Bacillus amyloliquefaciens	Type-2 restriction enzyme BamHI	IC50	300000.0	nM	10.1021/np0004606
Bacillus anthracis	Anthrax lethal factor	Potency	12589.3	nM	None
Bacillus subtilis	Bacillus subtilis	Activity	nan	None	10.1021/np50049a003
Bacteria	DNA	Activity	nan	None	10.1016/j.ejmech.2018.04.040
Bos taurus	Calf thymus DNA	Activity	nan	None	10.1021/np50078a006
Bos taurus	Deoxyribonuclease-1	IC50	300000.0	nM	10.1021/np0004606
Bos taurus	DNA topoisomerase	Activity	nan	None	10.1016/j.ejmech.2015.01.024
Bos taurus	DNA topoisomerase	Activity	nan	None	10.1021/np0004606
Bos taurus	DNA topoisomerase	IC50	17000.0	nM	10.1021/np0004606
Bos taurus	DNA topoisomerase	Inhibition	nan	%	10.1016/j.ejmech.2014.08.073
Bos taurus	DNA topoisomerase I	Activity	16.0	%	10.1016/j.bmc.2020.115527
Bos taurus	DNA topoisomerase I	Activity	18.0	%	10.1016/j.bmc.2020.115527
Bos taurus	DNA topoisomerase I	Activity	47.0	%	10.1021/acs.jnatprod.8b00430
Bos taurus	DNA topoisomerase I	Inhibition	51.0	%	10.1016/j.ejmech.2019.03.034
Bos taurus	DNA topoisomerase I	Inhibition	90.0	%	10.1021/acs.jnatprod.8b00430
Bos taurus	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2018.11.037
Bos taurus	Progesterone receptor	IC50	nan	None	None
Bos taurus	Progesterone receptor	Ki	nan	None	None
Bos taurus	Ribonuclease pancreatic	IC50	300000.0	nM	10.1021/np0004606
Bos taurus	Serum albumin	Kq	3.345	10'12L/mol/s	10.1016/j.bmcl.2014.10.048
Bos taurus	Serum albumin	Kq	3.626	10'12L/mol/s	10.1016/j.bmcl.2014.10.048
Bos taurus	Serum albumin	KSV	3.345	10'4L/mol	10.1016/j.bmcl.2014.10.048
Bos taurus	Serum albumin	KSV	3.626	10'4L/mol	10.1016/j.bmcl.2014.10.048
Bos taurus	Topoisomerase I	Activity	47.0	%	10.1016/j.ejmech.2018.04.040
Bos taurus	Topoisomerase I	Activity	49.0	%	10.1016/j.ejmech.2018.04.040
Bos taurus	Topoisomerase I	Inhibition	58.0	%	10.1016/j.ejmech.2018.04.040
Bos taurus	Topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2018.03.017
Bos taurus	Topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2011.03.024
Bos taurus	Topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2017.10.054
Bos taurus	Topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2018.04.040
Bos taurus	Topoisomerase I	Inhibition	nan	%	10.1039/C6MD00563B
Candida albicans	Candida albicans	Inhibition	4.14	%	10.6019/CHEMBL4296183
Cavia porcellus	Leukotriene C4 synthase	IC50	nan	None	None
Cavia porcellus	Leukotriene C4 synthase	Ki	nan	None	None
Cavia porcellus	Serotonin 4 (5-HT4) receptor	IC50	nan	None	None
Cavia porcellus	Serotonin 4 (5-HT4) receptor	Ki	nan	None	None
Chlorocebus aethiops	DNA topoisomerase 1	IC50	27000.0	nM	10.1021/np0004606
Chlorocebus sabaeus	Vero	IC50	0.02	ug.mL-1	10.1021/np50106a013
Chlorocebus sabaeus	Vero	IC50	0.054	ug.mL-1	10.1021/np50099a008
Chlorocebus sabaeus	Vero	IC50	0.054	ug.mL-1	10.1021/np9701687
Chlorocebus sabaeus	Vero	IC50	0.6	ug.mL-1	10.1021/np2004825
Chlorocebus sabaeus	Vero	IC50	58.0	ug.mL-1	10.1007/s00044-010-9381-7
Cricetulus griseus	CHO	Activity	1.2	%	10.1016/j.ejmech.2013.08.017
Cricetulus griseus	CHO	Activity	1.2	%	10.1039/C5MD00289C
Cricetulus griseus	CHO	Activity	2.4	%	10.1016/j.ejmech.2013.08.017
Cricetulus griseus	CHO	Activity	2.4	%	10.1039/C5MD00289C
Cricetulus griseus	CHO	Activity	21.6	%	10.1016/j.ejmech.2013.08.017
Cricetulus griseus	CHO	Activity	21.6	%	10.1039/C5MD00289C
Cricetulus griseus	CHO	Activity	50.5	%	10.1016/j.ejmech.2013.08.017
Cricetulus griseus	CHO	Activity	74.8	%	10.1016/j.ejmech.2013.08.017
Cricetulus griseus	CHO	Activity	74.8	%	10.1039/C5MD00289C
Cricetulus griseus	CHO	Activity	126.0	%	10.1016/j.ejmech.2014.09.049
Cricetulus griseus	CHO	Activity	nan	None	10.1016/j.bmcl.2011.01.013
Cricetulus griseus	CHO	Drug uptake	nan	None	10.1016/j.bmcl.2011.01.013
Cricetulus griseus	DC3F	IC50	6.0	nM	10.1016/S0960-894X(97)10181-0
Cryptococcus neoformans	Cryptococcus neoformans	Inhibition	-6.71	%	10.6019/CHEMBL4296183
Drosophila melanogaster	Drosophila melanogaster	GI	nan	None	10.1016/j.bmc.2011.09.059
Electrophorus electricus	Acetylcholinesterase	Inhibition	14.05	%	10.1016/j.bmc.2012.09.040
Entamoeba histolytica	Entamoeba histolytica	IC50	nan	None	10.1016/j.bmcl.2016.12.043
Enterobacteria phage T4	DNA ligase	IC50	300000.0	nM	10.1021/np0004606
Equus caballus	Cholinesterase	Inhibition	3.9	%	10.1016/j.bmc.2012.09.040
Equus caballus	Ferritin light chain	Potency	3162.3	nM	None
Equus caballus	Ferritin light chain	Potency	14125.4	nM	None
Escherichia coli	Escherichia coli	Activity	nan	None	10.1021/np50049a003
Escherichia coli	Escherichia coli	Inhibition	5.98	%	10.6019/CHEMBL4296183
Escherichia coli	Type-2 restriction enzyme EcoRI	IC50	300000.0	nM	10.1021/np0004606
Escherichia coli (strain K12)	DNA topoisomerase 1	Activity	nan	None	10.1021/acs.jmedchem.9b01626
Escherichia coli (strain K12)	DNA topoisomerase 1	Inhibition	nan	%	10.1016/j.bmc.2019.06.014
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	Type-2 restriction enzyme HindIII	IC50	300000.0	nM	10.1021/np0004606
Homo sapiens	15-hydroxyprostaglandin dehydrogenase [NAD+]	Potency	1995.3	nM	None
Homo sapiens	15-hydroxyprostaglandin dehydrogenase [NAD+]	Potency	2511.9	nM	None
Homo sapiens	15-hydroxyprostaglandin dehydrogenase [NAD+]	Potency	12589.3	nM	None
Homo sapiens	15-hydroxyprostaglandin dehydrogenase [NAD+]	Potency	31622.8	nM	None
Homo sapiens	1A9	ED50	3.2	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	23132-87	IC50	19.46	nM	10.6019/CHEMBL1201861
Homo sapiens	5637	IC50	4.183	nM	10.6019/CHEMBL1201861
Homo sapiens	639-V	IC50	0.1714	nM	10.6019/CHEMBL1201861
Homo sapiens	647-V	IC50	0.8964	nM	10.6019/CHEMBL1201861
Homo sapiens	697	IC50	2.029	nM	10.6019/CHEMBL1201861
Homo sapiens	769-P	IC50	25.34	nM	10.6019/CHEMBL1201861
Homo sapiens	786-0	GI50	21.38	nM	None
Homo sapiens	786-0	IC50	5.021	nM	10.6019/CHEMBL1201861
Homo sapiens	8305C	IC50	93.98	nM	10.6019/CHEMBL1201861
Homo sapiens	833K	IC50	10.0	nM	10.1016/S0960-894X(97)10181-0
Homo sapiens	8505C	IC50	3.301	nM	10.6019/CHEMBL1201861
Homo sapiens	8-MG-BA	IC50	1.502	nM	10.6019/CHEMBL1201861
Homo sapiens	A101D	IC50	257.84	nM	10.6019/CHEMBL1201861
Homo sapiens	A 172	GI	nan	None	10.1016/j.ejmech.2017.06.066
Homo sapiens	A 172	IC50	12.76	nM	10.6019/CHEMBL1201861
Homo sapiens	A 172	IC50	140.0	nM	10.1016/0960-894X(96)00131-X
Homo sapiens	A 172	IC50	140.0	nM	10.1016/0960-894X(96)00132-1
Homo sapiens	A204	IC50	4.525	nM	10.6019/CHEMBL1201861
Homo sapiens	A2058	IC50	3.599	nM	10.6019/CHEMBL1201861
Homo sapiens	A2780	GI50	460.0	nM	10.1016/j.bmc.2009.07.053
Homo sapiens	A2780	IC50	0.07	ug.mL-1	10.1021/np050351x
Homo sapiens	A2780	IC50	2.902	nM	10.6019/CHEMBL1201861
Homo sapiens	A2780	IC50	4.0	nM	10.1021/np010459m
Homo sapiens	A2780	IC50	7.0	nM	10.1016/j.bmcl.2003.08.012
Homo sapiens	A2780	IC50	7.0	nM	10.1016/j.bmcl.2012.06.016
Homo sapiens	A2780	IC50	13.0	nM	10.1021/ml400125z
Homo sapiens	A2780	IC50	29.0	nM	10.1016/j.ejmech.2016.11.013
Homo sapiens	A2780	IC50	200.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	A2780	IC50	200.0	nM	10.1021/np100583u
Homo sapiens	A2780	IC50	260.0	nM	10.1021/np200706n
Homo sapiens	A2780	IC50	280.0	nM	10.1021/np0703794
Homo sapiens	A2780	IC50	280.0	nM	10.1021/np900213w
Homo sapiens	A2780	IC50	280.0	nM	10.1021/np900504a
Homo sapiens	A2780	IC50	300.0	nM	10.1021/np800576s
Homo sapiens	A2780	IC50	300.0	nM	10.1021/np900305j
Homo sapiens	A2780	IC50	900.0	nM	10.1021/np400988a
Homo sapiens	A-375	Activity	nan	None	10.1016/j.ejmech.2014.06.050
Homo sapiens	A-375	IC50	3.688	nM	10.6019/CHEMBL1201861
Homo sapiens	A-375	IC50	13.0	nM	10.1021/acsmedchemlett.5b00441
Homo sapiens	A-375	IC50	187.0	nM	10.1016/j.ejmech.2014.06.050
Homo sapiens	A-375	IC50	660.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	A388	IC50	10.12	nM	10.6019/CHEMBL1201861
Homo sapiens	A3-KAW	IC50	1.669	nM	10.6019/CHEMBL1201861
Homo sapiens	A-427	IC50	4.251	nM	10.6019/CHEMBL1201861
Homo sapiens	A-427	IC50	24.0	nM	10.1021/jm980400l
Homo sapiens	A-431	Activity	65.0	%	10.1016/j.ejmech.2016.04.002
Homo sapiens	A-431	IC50	11.0	nM	10.1016/j.bmc.2010.09.069
Homo sapiens	A-431	IC50	1552.36	nM	10.6019/CHEMBL1201861
Homo sapiens	A498	GI50	32.21	nM	None
Homo sapiens	A498	IC50	7.077	nM	10.6019/CHEMBL1201861
Homo sapiens	A498	ID50	3.2	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	A4-Fuk	IC50	1.749	nM	10.6019/CHEMBL1201861
Homo sapiens	A549	Activity	0.072	ug ml-1	10.1016/j.bmcl.2009.03.042
Homo sapiens	A549	Activity	2.16	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	2.43	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	4.14	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	6.31	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	9.12	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	10.25	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	A549	Activity	10.49	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	11.17	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	14.14	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	A549	Activity	14.17	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	A549	Activity	19.0	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	19.2	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	20.33	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	A549	Activity	23.6	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	28.49	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	30.71	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	37.51	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	39.71	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	49.0	%	10.1016/j.ejmech.2014.09.049
Homo sapiens	A549	Activity	53.97	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	54.71	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	58.66	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	59.4	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	61.13	%	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	65.1	%	10.1039/C7MD00593H
Homo sapiens	A549	Activity	96.1	%	10.1016/j.ejmech.2014.09.049
Homo sapiens	A549	Activity	nan	None	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	Activity	nan	None	10.1016/j.bmcl.2017.05.006
Homo sapiens	A549	Activity	nan	None	10.1016/j.ejmech.2018.05.028
Homo sapiens	A549	Activity	nan	None	10.1016/j.ejmech.2022.114465
Homo sapiens	A549	Activity	nan	None	10.1021/acs.jnatprod.0c00986
Homo sapiens	A549	Activity	nan	None	10.1039/C7MD00593H
Homo sapiens	A549	Drug uptake	nan	None	10.1016/j.bmcl.2016.04.056
Homo sapiens	A549	ED50	6.9	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	A549	GI50	3.0	nM	10.1016/j.ejmech.2018.04.040
Homo sapiens	A549	GI50	7.0	nM	10.1016/j.bmc.2012.12.026
Homo sapiens	A549	GI50	10.0	nM	10.1021/jm900469e
Homo sapiens	A549	GI50	18.11	nM	None
Homo sapiens	A549	GI50	99.0	nM	10.1016/j.ejmech.2019.05.074
Homo sapiens	A549	GI50	170.0	nM	10.1021/jm300605m
Homo sapiens	A549	GI50	200.0	nM	10.1021/jm1009428
Homo sapiens	A549	GI50	210.0	nM	10.1021/acs.jmedchem.8b00639
Homo sapiens	A549	GI50	310.0	nM	10.1021/acs.jmedchem.1c00318
Homo sapiens	A549	GI50	2800.0	nM	10.1016/j.bmc.2007.12.028
Homo sapiens	A549	GI50	2800.0	nM	10.1021/jm1005447
Homo sapiens	A549	IC50	0.072	ug.mL-1	10.1016/j.bmc.2011.05.012
Homo sapiens	A549	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
Homo sapiens	A549	IC50	1.0	nM	10.1016/j.bmc.2021.116177
Homo sapiens	A549	IC50	1.0	nM	10.1016/j.bmcl.2021.128517
Homo sapiens	A549	IC50	1.0	nM	10.1016/j.ejmech.2016.03.031
Homo sapiens	A549	IC50	1.0	nM	10.1016/j.ejmech.2018.02.058
Homo sapiens	A549	IC50	1.0	nM	10.1016/j.ejmech.2019.06.032
Homo sapiens	A549	IC50	1.0	nM	10.1021/np400988a
Homo sapiens	A549	IC50	4.0	nM	10.1016/j.ejmech.2007.05.002
Homo sapiens	A549	IC50	5.379	nM	10.1021/jm901029n
Homo sapiens	A549	IC50	6.0	nM	10.1016/j.ejmech.2016.11.013
Homo sapiens	A549	IC50	8.0	nM	10.1016/j.bmcl.2003.08.012
Homo sapiens	A549	IC50	8.0	nM	10.1016/j.ejmech.2012.01.014
Homo sapiens	A549	IC50	8.63	nM	10.1016/j.bmcl.2017.02.066
Homo sapiens	A549	IC50	8.63	nM	10.1016/j.bmcl.2017.09.012
Homo sapiens	A549	IC50	9.0	nM	10.1021/acsmedchemlett.5b00441
Homo sapiens	A549	IC50	10.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	A549	IC50	10.0	nM	10.1021/np400483c
Homo sapiens	A549	IC50	14.0	nM	10.1021/jm0004751
Homo sapiens	A549	IC50	14.09	nM	10.6019/CHEMBL1201861
Homo sapiens	A549	IC50	15.8	nM	10.1016/j.bmcl.2012.10.002
Homo sapiens	A549	IC50	16.0	nM	10.1016/j.ejmech.2016.02.070
Homo sapiens	A549	IC50	16.0	nM	10.1021/jm5003588
Homo sapiens	A549	IC50	30.0	nM	10.1016/j.bmc.2010.10.042
Homo sapiens	A549	IC50	30.0	nM	10.1016/j.ejmech.2019.111700
Homo sapiens	A549	IC50	33.8	nM	10.1016/j.ejmech.2012.05.002
Homo sapiens	A549	IC50	39.0	nM	10.1021/acsmedchemlett.9b00513
Homo sapiens	A549	IC50	40.0	nM	10.1021/acs.jnatprod.8b00430
Homo sapiens	A549	IC50	40.0	nM	10.1021/jm900469e
Homo sapiens	A549	IC50	47.0	nM	10.1016/j.bmcl.2009.06.010
Homo sapiens	A549	IC50	57.0	nM	10.1021/jm100387d
Homo sapiens	A549	IC50	58.0	nM	10.1016/j.bmcl.2009.03.058
Homo sapiens	A549	IC50	67.0	nM	10.1016/j.bmcl.2007.08.062
Homo sapiens	A549	IC50	67.0	nM	10.1016/j.ejmech.2013.01.058
Homo sapiens	A549	IC50	67.0	nM	10.1021/jm000129j
Homo sapiens	A549	IC50	69.0	nM	10.1016/j.bmc.2010.10.057
Homo sapiens	A549	IC50	69.0	nM	10.1016/j.bmc.2011.01.064
Homo sapiens	A549	IC50	69.0	nM	10.1016/j.bmcl.2007.04.064
Homo sapiens	A549	IC50	74.0	nM	10.1016/j.bmc.2022.116793
Homo sapiens	A549	IC50	90.0	nM	10.1016/j.bmcl.2018.11.049
Homo sapiens	A549	IC50	91.0	nM	10.1016/j.bmc.2011.08.006
Homo sapiens	A549	IC50	99.0	nM	10.1021/ml400125z
Homo sapiens	A549	IC50	100.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	A549	IC50	100.0	nM	10.1021/acs.jmedchem.5b00910
Homo sapiens	A549	IC50	170.0	nM	10.1016/j.ejmech.2021.113544
Homo sapiens	A549	IC50	240.0	nM	10.1016/j.ejmech.2016.12.035
Homo sapiens	A549	IC50	260.0	nM	10.1016/j.bmcl.2017.03.039
Homo sapiens	A549	IC50	260.0	nM	10.1021/np200706n
Homo sapiens	A549	IC50	350.0	nM	10.1016/j.bmcl.2016.04.056
Homo sapiens	A549	IC50	370.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	A549	IC50	470.0	nM	10.1016/j.ejmech.2022.114465
Homo sapiens	A549	IC50	650.0	nM	10.1021/jm400906z
Homo sapiens	A549	IC50	700.0	nM	10.1016/j.bmcl.2017.05.006
Homo sapiens	A549	IC50	1000.0	nM	10.1016/j.bmc.2017.04.030
Homo sapiens	A549	IC50	1000.0	nM	10.1016/j.ejmech.2020.112292
Homo sapiens	A549	IC50	1300.0	nM	10.1016/j.ejmech.2014.07.035
Homo sapiens	A549	IC50	1310.0	nM	10.1016/j.bmcl.2018.10.014
Homo sapiens	A549	IC50	1560.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	A549	IC50	1600.0	nM	10.1016/j.ejmech.2015.07.007
Homo sapiens	A549	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	A549	IC50	2210.0	nM	10.1039/C8MD00278A
Homo sapiens	A549	IC50	2530.0	nM	10.1016/s0960-894x(02)01041-7
Homo sapiens	A549	IC50	2610.0	nM	10.1016/j.ejmech.2012.07.050
Homo sapiens	A549	IC50	2800.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	A549	IC50	3100.0	nM	10.1021/np800576s
Homo sapiens	A549	IC50	3120.0	nM	10.1021/np0703794
Homo sapiens	A549	IC50	3320.0	nM	10.1016/j.bmc.2019.03.028
Homo sapiens	A549	IC50	3600.0	nM	10.1021/np100583u
Homo sapiens	A549	IC50	4430.0	nM	10.1016/j.ejmech.2019.01.004
Homo sapiens	A549	IC50	5500.0	nM	10.1016/j.ejmech.2018.07.028
Homo sapiens	A549	IC50	5930.0	nM	10.1016/j.ejmech.2017.09.005
Homo sapiens	A549	IC50	8870.0	nM	10.1016/j.ejmech.2017.09.009
Homo sapiens	A549	IC50	8900.0	nM	10.1021/acs.jmedchem.1c01362
Homo sapiens	A549	IC50	13640.0	nM	10.1016/j.bmc.2017.03.065
Homo sapiens	A549	IC50	26450.0	nM	10.1016/j.ejmech.2015.01.024
Homo sapiens	A549	IC50	32100.0	nM	10.1016/j.ejmech.2020.113102
Homo sapiens	A549	IC50	32110.0	nM	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	IC50	37050.0	nM	10.1016/j.ejmech.2013.07.016
Homo sapiens	A549	IC50	50880.0	nM	10.1016/j.bmc.2019.03.011
Homo sapiens	A549	IC50	330000.0	nM	10.1016/s0960-894x(99)00555-7
Homo sapiens	A549	IC50	nan	nM	10.1016/j.bmcl.2003.09.001
Homo sapiens	A549	Inhibition	nan	%	10.1039/C3MD00193H
Homo sapiens	A673	IC50	0.8149	nM	10.6019/CHEMBL1201861
Homo sapiens	A704	IC50	15.35	nM	10.6019/CHEMBL1201861
Homo sapiens	ABC-1	IC50	3.468	nM	10.6019/CHEMBL1201861
Homo sapiens	Acetylcholinesterase	IC50	nan	None	None
Homo sapiens	Acetylcholinesterase	Inhibition	23.0	%	10.1021/jm0004751
Homo sapiens	Acetylcholinesterase	Ki	nan	None	None
Homo sapiens	ACHN	GI50	11.64	nM	None
Homo sapiens	ACHN	IC50	6.663	nM	10.6019/CHEMBL1201861
Homo sapiens	ACN	IC50	85.66	nM	10.6019/CHEMBL1201861
Homo sapiens	Adenosine A1 receptor	IC50	nan	None	None
Homo sapiens	Adenosine A1 receptor	Ki	nan	None	None
Homo sapiens	Adenosine A2a receptor	IC50	nan	None	None
Homo sapiens	Adenosine A2a receptor	Ki	nan	None	None
Homo sapiens	Adenosine A3 receptor	IC50	nan	None	None
Homo sapiens	Adenosine A3 receptor	Ki	nan	None	None
Homo sapiens	ADR5000 cell line	IC50	11.0	nM	10.1016/j.bmc.2017.02.005
Homo sapiens	AGS	GI50	10.0	nM	10.1021/jm900469e
Homo sapiens	AGS	GI50	23760.0	nM	10.1016/j.bmc.2007.12.028
Homo sapiens	AGS	IC50	16.13	nM	10.6019/CHEMBL1201861
Homo sapiens	AGS	IC50	20.0	nM	10.1021/jm900469e
Homo sapiens	AGS	IC50	23760.0	nM	10.1039/C4MD00133H
Homo sapiens	Aldehyde dehydrogenase 1A1	Potency	8912.5	nM	None
Homo sapiens	Aldehyde dehydrogenase 1A1	Potency	11220.2	nM	None
Homo sapiens	Aldehyde dehydrogenase 1A1	Potency	17782.8	nM	None
Homo sapiens	Aldehyde dehydrogenase 1A1	Potency	22387.2	nM	None
Homo sapiens	ALL-PO	IC50	1.534	nM	10.6019/CHEMBL1201861
Homo sapiens	Alpha-1d adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-1d adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-2a adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-2a adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-2b adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-2b adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-2c adrenergic receptor	IC50	nan	None	None
Homo sapiens	Alpha-2c adrenergic receptor	Ki	nan	None	None
Homo sapiens	Alpha-galactosidase A	Potency	1995.3	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	2238.7	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	3548.1	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	4466.8	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	8912.5	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	14125.4	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	17782.8	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	22387.2	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	35481.3	nM	None
Homo sapiens	Alpha-galactosidase A	Potency	39810.7	nM	None
Homo sapiens	AM-38	IC50	4.408	nM	10.6019/CHEMBL1201861
Homo sapiens	AN3-CA	IC50	33.98	nM	10.6019/CHEMBL1201861
Homo sapiens	Angiotensin II type 2 (AT-2) receptor	IC50	nan	None	None
Homo sapiens	Angiotensin II type 2 (AT-2) receptor	Ki	nan	None	None
Homo sapiens	Arachidonate 15-lipoxygenase	Potency	39810.7	nM	None
Homo sapiens	ASPC1	IC50	168.37	nM	10.6019/CHEMBL1201861
Homo sapiens	Ataxin-2	Potency	10.0	nM	None
Homo sapiens	Ataxin-2	Potency	1778.3	nM	None
Homo sapiens	ATN-1	IC50	2.043	nM	10.6019/CHEMBL1201861
Homo sapiens	ATPase family AAA domain-containing protein 5	Potency	460.9	nM	None
Homo sapiens	ATPase family AAA domain-containing protein 5	Potency	2908.1	nM	None
Homo sapiens	ATPase family AAA domain-containing protein 5	Potency	4609.0	nM	None
Homo sapiens	AU565	IC50	3.68	nM	10.6019/CHEMBL1201861
Homo sapiens	BALL-1	IC50	108.94	nM	10.6019/CHEMBL1201861
Homo sapiens	BB30-HNC	IC50	21.55	nM	10.6019/CHEMBL1201861
Homo sapiens	BB49-HNC	IC50	120.28	nM	10.6019/CHEMBL1201861
Homo sapiens	BB65-RCC	IC50	1.853	nM	10.6019/CHEMBL1201861
Homo sapiens	BCPAP	IC50	3.041	nM	10.6019/CHEMBL1201861
Homo sapiens	BE-13	IC50	4.564	nM	10.6019/CHEMBL1201861
Homo sapiens	Becker	IC50	23.34	nM	10.6019/CHEMBL1201861
Homo sapiens	Bel-7402	IC50	2.72	ug.mL-1	10.1016/j.bmcl.2004.05.032
Homo sapiens	Bel-7402	IC50	7.0	nM	10.1016/j.bmcl.2003.08.012
Homo sapiens	Bel-7402	IC50	14.0	nM	10.1016/j.ejmech.2016.11.013
Homo sapiens	Bel-7402	IC50	170.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	Bel-7402	IC50	260.0	nM	10.1021/np200706n
Homo sapiens	Bel-7402	IC50	12500.0	nM	10.1021/np0703794
Homo sapiens	Bel-7402	IC50	12500.0	nM	10.1021/np800576s
Homo sapiens	BEL-7404 tumor cell line	IC50	400.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	BEN	IC50	107.08	nM	10.6019/CHEMBL1201861
Homo sapiens	Beta-1 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-1 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Beta-2 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-2 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Beta-3 adrenergic receptor	IC50	nan	None	None
Homo sapiens	Beta-3 adrenergic receptor	Ki	nan	None	None
Homo sapiens	Beta-glucocerebrosidase	Potency	3162.3	nM	None
Homo sapiens	Beta-glucocerebrosidase	Potency	3548.1	nM	None
Homo sapiens	Beta-glucocerebrosidase	Potency	7079.5	nM	None
Homo sapiens	Beta-glucocerebrosidase	Potency	28183.8	nM	None
Homo sapiens	BFTC-905	IC50	0.1398	nM	10.6019/CHEMBL1201861
Homo sapiens	BFTC-909	IC50	6.925	nM	10.6019/CHEMBL1201861
Homo sapiens	BGC-823	IC50	57.0	nM	10.1016/j.ejmech.2016.11.013
Homo sapiens	BGC-823	IC50	210.0	nM	10.1021/np900504a
Homo sapiens	BGC-823	IC50	9670.0	nM	10.1021/np0703794
Homo sapiens	BGC-823	IC50	9700.0	nM	10.1021/np800576s
Homo sapiens	BGC-823	IC50	nan	None	10.1016/j.ejmech.2022.114376
Homo sapiens	BHT-101	IC50	1.822	nM	10.6019/CHEMBL1201861
Homo sapiens	BHY	IC50	5.31	nM	10.6019/CHEMBL1201861
Homo sapiens	Bile salt export pump	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Bile salt export pump	IC50	135000.0	nM	10.1093/toxsci/kfq269
Homo sapiens	BJ	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	BJ	EC50	7.67	nM	None
Homo sapiens	BJ	IC50	40000.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	Bloom syndrome protein	Potency	35481.3	nM	None
Homo sapiens	BPH-1	IC50	2.082	nM	10.6019/CHEMBL1201861
Homo sapiens	Bradykinin B2 receptor	IC50	nan	None	None
Homo sapiens	Bradykinin B2 receptor	Ki	nan	None	None
Homo sapiens	Bromodomain-containing protein 4	Delta TM	-1.84	C	None
Homo sapiens	BT-20	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	BT-20	IC50	25.99	nM	10.6019/CHEMBL1201861
Homo sapiens	BT-20	IC50	70.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	BT-474	IC50	1985.76	nM	10.6019/CHEMBL1201861
Homo sapiens	BT-474	IC50	12750.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	BT-549	GI50	114.82	nM	None
Homo sapiens	BT-549	IC50	17.64	nM	10.6019/CHEMBL1201861
Homo sapiens	BV-173	IC50	2.381	nM	10.6019/CHEMBL1201861
Homo sapiens	BXPC-3	IC50	116.78	nM	10.6019/CHEMBL1201861
Homo sapiens	BXPC-3	IC50	240.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	C2BBe1	IC50	2.438	nM	10.6019/CHEMBL1201861
Homo sapiens	C32	IC50	13.37	nM	10.6019/CHEMBL1201861
Homo sapiens	C-33-A	IC50	6.477	nM	10.6019/CHEMBL1201861
Homo sapiens	C3A	IC50	56.87	nM	10.6019/CHEMBL1201861
Homo sapiens	C8166	IC50	41.48	nM	10.6019/CHEMBL1201861
Homo sapiens	CA46	IC50	520.0	nM	10.1016/j.ejmech.2015.07.007
Homo sapiens	Ca9-22	IC50	2.211	nM	10.6019/CHEMBL1201861
Homo sapiens	Caco-2	Activity	0.12	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	1.4	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	1.64	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	2.76	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	3.04	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	3.18	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	4.1	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	4.32	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	13.7	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	13.94	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Activity	15.22	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	17.78	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Activity	27.06	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Activity	36.98	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	40.88	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Activity	41.38	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	50.18	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Activity	51.12	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	56.16	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	81.62	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	83.26	%	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	Activity	nan	None	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Activity	nan	None	10.1016/j.ejmech.2014.06.050
Homo sapiens	Caco-2	IC50	9550.0	nM	10.1016/j.ejmech.2011.07.036
Homo sapiens	Caco-2	Peff	1.0	ucm/s	10.1021/ml400125z
Homo sapiens	Caco-2	Peff	7.88	ucm/s	10.1021/ml400125z
Homo sapiens	CAKI-1	GI50	11.8	nM	None
Homo sapiens	CAKI-1	IC50	5.354	nM	10.6019/CHEMBL1201861
Homo sapiens	CAKI-2	IC50	3960.0	nM	10.1016/s0960-894x(02)01041-7
Homo sapiens	CAL-120	IC50	594.73	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-12T	IC50	262.05	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-27	IC50	2.018	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-33	IC50	5.997	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-39	IC50	19.16	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-51	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	CAL-51	IC50	29.74	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-54	IC50	4.758	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-62	IC50	0.9836	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-72	IC50	150.57	nM	10.6019/CHEMBL1201861
Homo sapiens	CAL-85-1	IC50	7923.68	nM	10.6019/CHEMBL1201861
Homo sapiens	Calcitonin receptor	IC50	nan	None	None
Homo sapiens	Calcitonin receptor	Ki	nan	None	None
Homo sapiens	Calu-3	IC50	32.8	nM	10.6019/CHEMBL1201861
Homo sapiens	Calu-6	IC50	178.95	nM	10.6019/CHEMBL1201861
Homo sapiens	CAMA-1	IC50	70.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	CAMA-1	IC50	70.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	CAMA-1	IC50	87.43	nM	10.6019/CHEMBL1201861
Homo sapiens	Canalicular multispecific organic anion transporter 1	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Canalicular multispecific organic anion transporter 2	IC50	133000.0	nM	10.1093/toxsci/kft176
Homo sapiens	Cannabinoid CB1 receptor	IC50	nan	None	None
Homo sapiens	Cannabinoid CB1 receptor	Ki	nan	None	None
Homo sapiens	Caov-3 cell line	IC50	30.0	nM	10.1016/0960-894X(96)00131-X
Homo sapiens	Caov-3 cell line	IC50	30.0	nM	10.1016/0960-894X(96)00132-1
Homo sapiens	Caov-3 cell line	IC50	2900000.0	nM	10.1016/s0960-894x(99)00555-7
Homo sapiens	CAPAN-1	IC50	14.95	nM	10.6019/CHEMBL1201861
Homo sapiens	CAPAN-1	IC50	210.0	nM	10.1016/j.bmc.2018.06.032
Homo sapiens	CAPAN-1	IC50	nan	None	10.1016/j.bmc.2018.06.032
Homo sapiens	Capan-2	IC50	452.29	nM	10.6019/CHEMBL1201861
Homo sapiens	CaR-1	IC50	6.427	nM	10.6019/CHEMBL1201861
Homo sapiens	Carbonic anhydrase II	IC50	nan	None	None
Homo sapiens	Carbonic anhydrase II	Ki	nan	None	None
Homo sapiens	CAS-1	IC50	121.91	nM	10.6019/CHEMBL1201861
Homo sapiens	Casein kinase I delta	Delta TM	0.03	C	None
Homo sapiens	Ca-Ski	Activity	2.0	%	10.1016/j.ejmech.2018.01.020
Homo sapiens	Ca-Ski	Activity	62.0	%	10.1016/j.ejmech.2018.01.020
Homo sapiens	Ca-Ski	IC50	4.97	nM	10.6019/CHEMBL1201861
Homo sapiens	Ca-Ski	IC50	1800.0	nM	10.1016/j.ejmech.2018.01.020
Homo sapiens	Caspase-1	IC50	nan	None	None
Homo sapiens	Caspase-1	Ki	nan	None	None
Homo sapiens	Cathepsin G	IC50	nan	None	None
Homo sapiens	Cathepsin G	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 2	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 2	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 4	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 4	Ki	nan	None	None
Homo sapiens	C-C chemokine receptor type 5	IC50	nan	None	None
Homo sapiens	C-C chemokine receptor type 5	Ki	nan	None	None
Homo sapiens	CCD 19Lu	IC50	2.0	ug.mL-1	10.1016/S0960-894X(97)00071-1
Homo sapiens	CCRF-CEM	Activity	10.3	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	15.5	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	17.5	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	18.0	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	21.7	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	23.6	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	28.4	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	34.6	%	10.1021/np8007232
Homo sapiens	CCRF-CEM	Activity	nan	None	10.1016/j.bmc.2017.02.005
Homo sapiens	CCRF-CEM	Activity	nan	None	10.1021/acs.jmedchem.6b01565
Homo sapiens	CCRF-CEM	Activity	nan	None	10.1021/acs.jmedchem.6b01870
Homo sapiens	CCRF-CEM	CC50	3.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	CCRF-CEM	CC50	3.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	CCRF-CEM	GI50	0.023	nM	10.1021/jm9005059
Homo sapiens	CCRF-CEM	GI50	2.0	nM	10.1016/j.bmc.2007.03.067
Homo sapiens	CCRF-CEM	GI50	2.0	nM	10.1016/j.ejmech.2018.04.040
Homo sapiens	CCRF-CEM	GI50	2.0	nM	10.1021/jm400575x
Homo sapiens	CCRF-CEM	GI50	7.0	nM	10.1021/acs.jmedchem.8b00639
Homo sapiens	CCRF-CEM	GI50	10.0	nM	None
Homo sapiens	CCRF-CEM	IC50	0.005	ug.mL-1	10.1016/S0960-894X(97)00071-1
Homo sapiens	CCRF-CEM	IC50	0.84	nM	10.1021/jm049060w
Homo sapiens	CCRF-CEM	IC50	2.0	nM	10.1021/acs.jnatprod.8b00430
Homo sapiens	CCRF-CEM	IC50	3.0	nM	10.1016/j.bmc.2017.02.005
Homo sapiens	CCRF-CEM	IC50	3.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	CCRF-CEM	IC50	5.0	nM	10.1016/j.ejmech.2012.01.040
Homo sapiens	CCRF-CEM	IC50	5.547	nM	10.6019/CHEMBL1201861
Homo sapiens	CCRF-CEM	IC50	40.0	nM	10.1021/np8007232
Homo sapiens	CCRF-CEM	IC50	80.0	nM	10.1021/np400672g
Homo sapiens	CCRF-CEM	IC50	5300.0	nM	10.1021/jm030253d
Homo sapiens	CCRF-CEM	RatioGI50	500.0	None	10.1021/jm400575x
Homo sapiens	CCRF-CEM	RatioGI50	1879.0	None	10.1021/jm9005059
Homo sapiens	CCRF-CEM	RRI	6400.0	None	10.1021/jm049060w
Homo sapiens	CCRF-SB	CC50	4.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	CCRF-SB	CC50	4.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	CCRF-SB	IC50	3.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	Cellular tumor antigen p53	Potency	25.1	nM	None
Homo sapiens	Cellular tumor antigen p53	Potency	199.5	nM	None
Homo sapiens	Cellular tumor antigen p53	Potency	251.2	nM	None
Homo sapiens	CEM/C2	GI50	1000.0	nM	10.1016/j.bmc.2007.03.067
Homo sapiens	CEM/C2	GI50	1000.0	nM	10.1021/jm400575x
Homo sapiens	CEM/C2	RatioGI50	500.0	None	10.1016/j.bmc.2007.03.067
Homo sapiens	CFPAC-1	IC50	14.75	nM	10.6019/CHEMBL1201861
Homo sapiens	CGTH-W-1	IC50	3.275	nM	10.6019/CHEMBL1201861
Homo sapiens	ChaGo-K-1	IC50	304.67	nM	10.6019/CHEMBL1201861
Homo sapiens	CHL-1	IC50	6.091	nM	10.6019/CHEMBL1201861
Homo sapiens	Cholecystokinin A receptor	IC50	nan	None	None
Homo sapiens	Cholecystokinin A receptor	Ki	nan	None	None
Homo sapiens	CHP-212	IC50	1.026	nM	10.6019/CHEMBL1201861
Homo sapiens	Chromobox protein homolog 1	Potency	50118.7	nM	None
Homo sapiens	CNE	IC50	340.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	CNE-2	IC50	100.0	nM	10.1016/j.ejmech.2018.07.028
Homo sapiens	CNE-2	IC50	980.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	Col2	ED50	57.0	nM	10.1021/np0304417
Homo sapiens	Col2	IC50	45.0	nM	10.1016/j.bmc.2010.10.057
Homo sapiens	Col2	IC50	45.0	nM	10.1016/j.bmc.2011.01.064
Homo sapiens	Col2	IC50	45.0	nM	10.1016/j.bmcl.2007.04.064
Homo sapiens	COLO 205	Activity	0.0	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	2.2	%	10.1016/j.ejmech.2014.07.069
Homo sapiens	COLO 205	Activity	4.9	%	10.1016/j.ejmech.2014.07.069
Homo sapiens	COLO 205	Activity	11.0	%	10.1016/j.ejmech.2014.07.069
Homo sapiens	COLO 205	Activity	17.0	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	19.5	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	23.5	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	29.0	%	10.1016/j.bmcl.2015.03.065
Homo sapiens	COLO 205	Activity	30.0	%	10.1016/j.bmcl.2015.03.065
Homo sapiens	COLO 205	Activity	30.8	%	10.1016/j.ejmech.2014.07.069
Homo sapiens	COLO 205	Activity	37.3	%	10.1016/j.bmcl.2019.126760
Homo sapiens	COLO 205	Activity	40.0	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	42.0	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	48.5	%	10.1016/j.bmcl.2015.03.065
Homo sapiens	COLO 205	Activity	53.0	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	59.3	%	10.1016/j.bmcl.2019.126760
Homo sapiens	COLO 205	Activity	62.0	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	79.6	%	10.1016/j.ejmech.2014.07.069
Homo sapiens	COLO 205	Activity	80.5	%	10.1039/C3MD00399J
Homo sapiens	COLO 205	Activity	nan	None	10.1016/j.bmc.2012.01.039
Homo sapiens	COLO 205	GI50	285.76	nM	None
Homo sapiens	COLO 205	IC50	5.4	nM	10.1021/jm990124q
Homo sapiens	COLO 205	IC50	50.0	nM	10.1021/np400433g
Homo sapiens	COLO-320-HSR	IC50	62.09	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-668	IC50	22.32	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-678	IC50	3682.73	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-679	IC50	4791.52	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-680N	IC50	72.45	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-684	IC50	13.82	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-741	IC50	109.27	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-792	IC50	169.17	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-800	IC50	0.4281	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-824	IC50	269.5	nM	10.6019/CHEMBL1201861
Homo sapiens	COLO-829	IC50	11.67	nM	10.6019/CHEMBL1201861
Homo sapiens	COR-L105	IC50	184.93	nM	10.6019/CHEMBL1201861
Homo sapiens	COR-L23	IC50	6.849	nM	10.6019/CHEMBL1201861
Homo sapiens	COR-L88	IC50	40.93	nM	10.6019/CHEMBL1201861
Homo sapiens	CP50-MEL-B	IC50	72.08	nM	10.6019/CHEMBL1201861
Homo sapiens	CP66-MEL	IC50	208.15	nM	10.6019/CHEMBL1201861
Homo sapiens	CTB-1	IC50	0.4292	nM	10.6019/CHEMBL1201861
Homo sapiens	CTV-1	IC50	0.9054	nM	10.6019/CHEMBL1201861
Homo sapiens	CW-2	IC50	35.45	nM	10.6019/CHEMBL1201861
Homo sapiens	CWR22R	IC50	9.314	nM	10.6019/CHEMBL1201861
Homo sapiens	Cyclin-dependent kinase 2	Delta TM	0.46	C	None
Homo sapiens	Cyclooxygenase-1	IC50	nan	None	None
Homo sapiens	Cyclooxygenase-1	Ki	nan	None	None
Homo sapiens	Cyclooxygenase-2	IC50	nan	None	None
Homo sapiens	Cyclooxygenase-2	Ki	nan	None	None
Homo sapiens	Cysteinyl leukotriene receptor 1	IC50	nan	None	None
Homo sapiens	Cysteinyl leukotriene receptor 1	Ki	nan	None	None
Homo sapiens	Cytochrome c oxidase subunit 2	IC50	nan	None	10.1021/acs.jmedchem.2c00635
Homo sapiens	Cytochrome P450 1A2	AC50	1584.89	nM	None
Homo sapiens	Cytochrome P450 1A2	AC50	2511.89	nM	None
Homo sapiens	Cytochrome P450 1A2	IC50	nan	None	None
Homo sapiens	Cytochrome P450 1A2	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2A6	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2A6	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2C19	AC50	19952.62	nM	None
Homo sapiens	Cytochrome P450 2C19	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2C19	Potency	19952.6	nM	None
Homo sapiens	Cytochrome P450 2C9	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2D6	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2D6	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2D6	Ki	nan	None	None
Homo sapiens	Cytochrome P450 2E1	IC50	nan	None	None
Homo sapiens	Cytochrome P450 2E1	Ki	nan	None	None
Homo sapiens	Cytochrome P450 3A4	AC50	6309.57	nM	None
Homo sapiens	Cytochrome P450 3A4	AC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	IC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	Ki	nan	None	None
Homo sapiens	Cytochrome P450 3A4	Potency	6309.6	nM	None
Homo sapiens	D-247MG	IC50	39.54	nM	10.6019/CHEMBL1201861
Homo sapiens	D-263MG	IC50	9.114	nM	10.6019/CHEMBL1201861
Homo sapiens	D283 Med	IC50	3.198	nM	10.6019/CHEMBL1201861
Homo sapiens	D-336MG	IC50	5.205	nM	10.6019/CHEMBL1201861
Homo sapiens	D-392MG	IC50	17.73	nM	10.6019/CHEMBL1201861
Homo sapiens	D-423MG	IC50	2.551	nM	10.6019/CHEMBL1201861
Homo sapiens	D-502MG	IC50	22.59	nM	10.6019/CHEMBL1201861
Homo sapiens	D-542MG	IC50	291.41	nM	10.6019/CHEMBL1201861
Homo sapiens	D-566MG	IC50	0.1315	nM	10.6019/CHEMBL1201861
Homo sapiens	Daoy	IC50	0.4809	nM	10.6019/CHEMBL1201861
Homo sapiens	DB	IC50	1.161	nM	10.6019/CHEMBL1201861
Homo sapiens	DBTRG-05MG	IC50	40.86	nM	10.6019/CHEMBL1201861
Homo sapiens	DEL	IC50	0.8157	nM	10.6019/CHEMBL1201861
Homo sapiens	Delta opioid receptor	IC50	nan	None	None
Homo sapiens	Delta opioid receptor	Ki	nan	None	None
Homo sapiens	Detroit 551	GI50	990.0	nM	10.1016/j.bmc.2010.05.062
Homo sapiens	Detroit 551	GI50	990.0	nM	10.1021/jm1005447
Homo sapiens	Detroit 551	IC50	990.0	nM	10.1039/C4MD00133H
Homo sapiens	Detroit 551	RatioGI50	0.35	None	10.1021/jm1005447
Homo sapiens	Detroit 551	RatioGI50	0.96	None	10.1021/jm1005447
Homo sapiens	Detroit 551	RatioGI50	4.5	None	10.1021/jm1005447
Homo sapiens	Detroit 551	RatioGI50	11.0	None	10.1021/jm1005447
Homo sapiens	Detroit 562	IC50	13.34	nM	10.6019/CHEMBL1201861
Homo sapiens	DJM-1	IC50	436.47	nM	10.6019/CHEMBL1201861
Homo sapiens	DK-MG	IC50	84.75	nM	10.6019/CHEMBL1201861
Homo sapiens	DLD-1	GI50	242.66	nM	None
Homo sapiens	DLD-1	IC50	210.0	nM	10.1016/0960-894X(96)00131-X
Homo sapiens	DLD-1	IC50	210.0	nM	10.1016/0960-894X(96)00132-1
Homo sapiens	DLD-1	IC50	14000000.0	nM	10.1016/s0960-894x(99)00555-7
Homo sapiens	DMS-114	GI50	20.56	nM	None
Homo sapiens	DMS-114	IC50	81.1	nM	10.6019/CHEMBL1201861
Homo sapiens	DMS-273	GI50	10.0	nM	None
Homo sapiens	DMS-273	IC50	6.072	nM	10.6019/CHEMBL1201861
Homo sapiens	DMS-79	IC50	31.85	nM	10.6019/CHEMBL1201861
Homo sapiens	DNA polymerase iota	Potency	89125.1	nM	None
Homo sapiens	DNA topoisomerase I	Activity	0.2	None	10.1016/j.bmc.2008.08.018
Homo sapiens	DNA topoisomerase I	Activity	0.2	None	10.1016/j.bmc.2009.02.023
Homo sapiens	DNA topoisomerase I	Activity	0.2	None	10.1016/j.bmcl.2008.05.005
Homo sapiens	DNA topoisomerase I	Activity	0.2	None	10.1016/j.ejmech.2009.02.004
Homo sapiens	DNA topoisomerase I	Activity	0.77	None	10.1016/s0960-894x(03)00534-1
Homo sapiens	DNA topoisomerase I	Activity	2.1	%	10.1016/j.bmc.2020.115443
Homo sapiens	DNA topoisomerase I	Activity	6.0	%	10.1016/j.bmc.2020.115443
Homo sapiens	DNA topoisomerase I	Activity	25.0	%	10.1016/j.ejmech.2017.11.011
Homo sapiens	DNA topoisomerase I	Activity	26.3	%	10.1016/j.bmc.2020.115443
Homo sapiens	DNA topoisomerase I	Activity	40.0	%	10.1021/acs.jmedchem.7b01297
Homo sapiens	DNA topoisomerase I	Activity	41.0	%	10.1016/j.bmcl.2019.126925
Homo sapiens	DNA topoisomerase I	Activity	48.0	%	10.1016/j.bmcl.2019.126925
Homo sapiens	DNA topoisomerase I	Activity	84.0	%	10.1021/jm900469e
Homo sapiens	DNA topoisomerase I	Activity	90.0	%	10.1021/np990442s
Homo sapiens	DNA topoisomerase I	Activity	100.0	%	10.1021/acs.jmedchem.6b00003
Homo sapiens	DNA topoisomerase I	Activity	100.0	%	10.1021/np8007232
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmc.2007.01.034
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmc.2010.06.040
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmc.2010.10.054
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmc.2018.02.045
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmc.2021.116177
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmc.2022.116723
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmcl.2003.09.001
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmcl.2007.08.062
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.bmcl.2019.126925
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2009.03.026
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2015.01.024
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2015.01.038
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2015.07.007
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2016.01.050
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2016.08.045
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2016.12.035
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2017.11.011
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2019.01.015
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2019.05.074
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1016/j.ejmech.2020.112292
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/acs.jmedchem.1c01411
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/acs.jmedchem.5b00136
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/acs.jmedchem.6b01502
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/acs.jmedchem.7b01297
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/acs.jmedchem.8b01938
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/jm000029d
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/jm501244f
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/jm900469e
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/np000058r
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/np300299y
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1021/np50082a001
Homo sapiens	DNA topoisomerase I	Activity	nan	None	10.1039/C5MD00502G
Homo sapiens	DNA topoisomerase I	CC50	800.0	nM	10.1021/jm00123a038
Homo sapiens	DNA topoisomerase I	CC50	820.0	nM	10.1021/jm00105a017
Homo sapiens	DNA topoisomerase I	Change	3.0	%	10.1021/jm950465d
Homo sapiens	DNA topoisomerase I	Change	6.0	%	10.1021/jm950465d
Homo sapiens	DNA topoisomerase I	Change	7.0	%	10.1021/jm950465d
Homo sapiens	DNA topoisomerase I	Change	9.0	%	10.1021/jm950465d
Homo sapiens	DNA topoisomerase I	Change	12.0	%	10.1021/jm950465d
Homo sapiens	DNA topoisomerase I	Cleavage	325.0	%	10.1021/jm050076b
Homo sapiens	DNA topoisomerase I	DNA cleavage	nan	None	10.1021/jm040025z
Homo sapiens	DNA topoisomerase I	EC50	350.0	nM	10.1016/j.bmcl.2004.08.010
Homo sapiens	DNA topoisomerase I	Effect	2.0	%	10.1016/j.bmcl.2004.10.095
Homo sapiens	DNA topoisomerase I	Effect	84.0	%	10.1016/j.bmcl.2004.10.095
Homo sapiens	DNA topoisomerase I	Effect	96.0	%	10.1016/j.bmcl.2004.10.095
Homo sapiens	DNA topoisomerase I	FC	1.0	None	10.1016/j.ejmech.2010.03.013
Homo sapiens	DNA topoisomerase I	FC	2.0	None	10.1016/j.bmc.2018.02.045
Homo sapiens	DNA topoisomerase I	FC	2.3	None	10.1016/j.bmc.2018.02.045
Homo sapiens	DNA topoisomerase I	FC	2.5	None	10.1016/j.bmc.2018.02.045
Homo sapiens	DNA topoisomerase I	Fluorescence intensity	1.04	None	10.1021/np060609z
Homo sapiens	DNA topoisomerase I	Fluorescence intensity	1.58	None	10.1021/np060609z
Homo sapiens	DNA topoisomerase I	Fluorescence intensity	2.51	None	10.1021/np060609z
Homo sapiens	DNA topoisomerase I	Fluorescence intensity	11.39	None	10.1021/np060609z
Homo sapiens	DNA topoisomerase I	IC10	0.2	nM	10.1016/j.bmc.2008.06.046
Homo sapiens	DNA topoisomerase I	IC50	25.0	nM	10.1016/j.ejmech.2020.112551
Homo sapiens	DNA topoisomerase I	IC50	25.0	nM	10.1021/acs.jmedchem.8b01938
Homo sapiens	DNA topoisomerase I	IC50	224.0	nM	10.1016/j.ejmech.2021.113768
Homo sapiens	DNA topoisomerase I	IC50	300.0	nM	10.1021/jm049146p
Homo sapiens	DNA topoisomerase I	IC50	679.0	nM	10.1021/jm00003a001
Homo sapiens	DNA topoisomerase I	IC50	680.0	nM	10.1021/jm00070a013
Homo sapiens	DNA topoisomerase I	IC50	700.0	nM	10.1016/0960-894X(95)00360-6
Homo sapiens	DNA topoisomerase I	IC50	700.0	nM	10.1016/S0960-894X(01)80589-8
Homo sapiens	DNA topoisomerase I	IC50	700.0	nM	10.1021/jm00007a008
Homo sapiens	DNA topoisomerase I	IC50	700.0	nM	10.1021/jm9605804
Homo sapiens	DNA topoisomerase I	IC50	2200.0	nM	10.1021/jm1005447
Homo sapiens	DNA topoisomerase I	IC50	2430.0	nM	10.1021/acs.jmedchem.2c00635
Homo sapiens	DNA topoisomerase I	IC50	2500.0	nM	10.1016/j.ejmech.2020.112551
Homo sapiens	DNA topoisomerase I	IC50	2500.0	nM	10.1021/acs.jmedchem.8b01938
Homo sapiens	DNA topoisomerase I	IC50	3750.0	nM	10.1007/s00044-009-9233-5
Homo sapiens	DNA topoisomerase I	IC50	4000.0	nM	10.1021/np0004606
Homo sapiens	DNA topoisomerase I	IC50	4750.0	nM	10.1007/s00044-009-9233-5
Homo sapiens	DNA topoisomerase I	IC50	4950.0	nM	10.1007/s00044-009-9233-5
Homo sapiens	DNA topoisomerase I	IC50	9000.0	nM	10.1021/np0004606
Homo sapiens	DNA topoisomerase I	IC50	17000.0	nM	10.1021/np0004606
Homo sapiens	DNA topoisomerase I	IC50	20000.0	nM	10.1016/j.ejmech.2022.114465
Homo sapiens	DNA topoisomerase I	IC50	20000.0	nM	10.1021/np058007n
Homo sapiens	DNA topoisomerase I	IC50	27000.0	nM	10.1016/j.ejmech.2019.03.040
Homo sapiens	DNA topoisomerase I	IC50	62000.0	nM	10.1016/j.ejmech.2020.112870
Homo sapiens	DNA topoisomerase I	IC50	62900.0	nM	10.1021/acs.jmedchem.0c00727
Homo sapiens	DNA topoisomerase I	IC50	127000.0	nM	10.1021/jm00006a025
Homo sapiens	DNA topoisomerase I	IC50	nan	None	10.1016/j.bmc.2010.10.057
Homo sapiens	DNA topoisomerase I	IC50	nan	None	10.1016/j.ejmech.2018.10.065
Homo sapiens	DNA topoisomerase I	Inhibition	0.0	%	10.1016/j.ejmech.2018.02.058
Homo sapiens	DNA topoisomerase I	Inhibition	0.77	%	10.1016/j.ejmech.2013.01.058
Homo sapiens	DNA topoisomerase I	Inhibition	3.0	%	10.1016/j.bmc.2021.116177
Homo sapiens	DNA topoisomerase I	Inhibition	3.0	%	10.1016/j.bmcl.2021.128517
Homo sapiens	DNA topoisomerase I	Inhibition	3.0	%	10.1016/j.ejmech.2019.06.032
Homo sapiens	DNA topoisomerase I	Inhibition	17.0	%	10.1016/j.ejmech.2018.02.058
Homo sapiens	DNA topoisomerase I	Inhibition	19.6	%	10.1016/j.bmc.2017.03.065
Homo sapiens	DNA topoisomerase I	Inhibition	19.6	%	10.1016/j.ejmech.2016.09.019
Homo sapiens	DNA topoisomerase I	Inhibition	20.9	%	10.1016/j.bmc.2015.04.031
Homo sapiens	DNA topoisomerase I	Inhibition	20.9	%	10.1016/j.ejmech.2011.04.029
Homo sapiens	DNA topoisomerase I	Inhibition	21.6	%	10.1016/j.ejmech.2017.03.048
Homo sapiens	DNA topoisomerase I	Inhibition	22.0	%	10.1016/j.ejmech.2017.01.003
Homo sapiens	DNA topoisomerase I	Inhibition	23.1	%	10.1016/j.ejmech.2012.03.010
Homo sapiens	DNA topoisomerase I	Inhibition	23.8	%	10.1016/j.ejmech.2017.11.011
Homo sapiens	DNA topoisomerase I	Inhibition	24.6	%	10.1016/j.bmc.2016.03.017
Homo sapiens	DNA topoisomerase I	Inhibition	25.0	%	10.1016/j.ejmech.2022.114304
Homo sapiens	DNA topoisomerase I	Inhibition	25.0	%	10.1021/jm950465d
Homo sapiens	DNA topoisomerase I	Inhibition	25.1	%	10.1016/j.ejmech.2016.09.004
Homo sapiens	DNA topoisomerase I	Inhibition	26.0	%	10.1016/j.ejmech.2012.01.040
Homo sapiens	DNA topoisomerase I	Inhibition	26.1	%	10.1016/j.ejmech.2013.07.048
Homo sapiens	DNA topoisomerase I	Inhibition	26.9	%	10.1016/j.ejmech.2015.08.040
Homo sapiens	DNA topoisomerase I	Inhibition	27.0	%	10.1016/j.ejmech.2012.01.040
Homo sapiens	DNA topoisomerase I	Inhibition	27.6	%	10.1016/j.bmcl.2016.02.053
Homo sapiens	DNA topoisomerase I	Inhibition	28.5	%	10.1016/j.ejmech.2017.11.011
Homo sapiens	DNA topoisomerase I	Inhibition	30.6	%	10.1016/j.ejmech.2013.08.040
Homo sapiens	DNA topoisomerase I	Inhibition	33.8	%	10.1016/j.bmc.2016.09.051
Homo sapiens	DNA topoisomerase I	Inhibition	34.3	%	10.1016/j.bmc.2018.02.035
Homo sapiens	DNA topoisomerase I	Inhibition	34.7	%	10.1016/j.ejmech.2016.02.050
Homo sapiens	DNA topoisomerase I	Inhibition	35.5	%	10.1016/j.ejmech.2014.05.047
Homo sapiens	DNA topoisomerase I	Inhibition	36.0	%	10.1016/S0960-894X(97)00398-3
Homo sapiens	DNA topoisomerase I	Inhibition	37.2	%	10.1016/j.bmcl.2013.03.106
Homo sapiens	DNA topoisomerase I	Inhibition	38.2	%	10.1021/acs.jmedchem.9b00970
Homo sapiens	DNA topoisomerase I	Inhibition	39.5	%	10.1016/j.bmc.2010.01.065
Homo sapiens	DNA topoisomerase I	Inhibition	40.05	%	10.1016/j.ejmech.2022.114560
Homo sapiens	DNA topoisomerase I	Inhibition	40.3	%	10.1016/j.bmc.2010.03.051
Homo sapiens	DNA topoisomerase I	Inhibition	40.8	%	10.1016/j.bmc.2015.04.002
Homo sapiens	DNA topoisomerase I	Inhibition	41.2	%	10.1016/j.bmc.2009.10.049
Homo sapiens	DNA topoisomerase I	Inhibition	44.4	%	10.1016/j.bmc.2018.09.019
Homo sapiens	DNA topoisomerase I	Inhibition	44.7	%	10.1016/j.bmc.2015.08.018
Homo sapiens	DNA topoisomerase I	Inhibition	45.2	%	10.1016/j.ejmech.2016.09.019
Homo sapiens	DNA topoisomerase I	Inhibition	45.6	%	10.1016/j.bmcl.2018.01.048
Homo sapiens	DNA topoisomerase I	Inhibition	45.8	%	10.1016/j.bmc.2018.09.021
Homo sapiens	DNA topoisomerase I	Inhibition	46.6	%	10.1016/j.ejmech.2012.03.010
Homo sapiens	DNA topoisomerase I	Inhibition	47.0	%	10.1016/j.bmc.2006.09.040
Homo sapiens	DNA topoisomerase I	Inhibition	47.89	%	10.1016/j.bmc.2021.116595
Homo sapiens	DNA topoisomerase I	Inhibition	50.0	%	10.1016/j.bmcl.2004.04.094
Homo sapiens	DNA topoisomerase I	Inhibition	52.14	%	10.1016/j.ejmech.2022.114560
Homo sapiens	DNA topoisomerase I	Inhibition	52.7	%	10.1016/j.bmc.2015.08.018
Homo sapiens	DNA topoisomerase I	Inhibition	53.03	%	10.1016/j.ejmech.2017.11.011
Homo sapiens	DNA topoisomerase I	Inhibition	54.79	%	10.1021/acs.jmedchem.2c00635
Homo sapiens	DNA topoisomerase I	Inhibition	55.8	%	10.1016/j.ejmech.2017.01.003
Homo sapiens	DNA topoisomerase I	Inhibition	58.0	%	10.1016/j.bmc.2015.04.031
Homo sapiens	DNA topoisomerase I	Inhibition	58.0	%	10.1016/j.ejmech.2011.04.029
Homo sapiens	DNA topoisomerase I	Inhibition	58.2	%	10.1016/j.bmc.2017.03.065
Homo sapiens	DNA topoisomerase I	Inhibition	58.7	%	10.1016/j.bmcl.2016.02.053
Homo sapiens	DNA topoisomerase I	Inhibition	58.92	%	10.1016/j.ejmech.2021.113960
Homo sapiens	DNA topoisomerase I	Inhibition	59.9	%	10.1016/j.ejmech.2012.01.015
Homo sapiens	DNA topoisomerase I	Inhibition	60.0	%	10.1016/j.bmc.2012.05.030
Homo sapiens	DNA topoisomerase I	Inhibition	61.0	%	10.1016/j.ejmech.2018.02.058
Homo sapiens	DNA topoisomerase I	Inhibition	63.0	%	10.1016/j.ejmech.2017.03.048
Homo sapiens	DNA topoisomerase I	Inhibition	64.3	%	10.1016/j.bmcl.2010.11.037
Homo sapiens	DNA topoisomerase I	Inhibition	64.7	%	10.1016/j.ejmech.2016.02.050
Homo sapiens	DNA topoisomerase I	Inhibition	65.7	%	10.1016/j.ejmech.2014.07.058
Homo sapiens	DNA topoisomerase I	Inhibition	66.7	%	10.1016/j.bmc.2018.09.019
Homo sapiens	DNA topoisomerase I	Inhibition	67.1	%	10.1016/j.bmcl.2009.09.091
Homo sapiens	DNA topoisomerase I	Inhibition	67.5	%	10.1021/acs.jmedchem.9b00970
Homo sapiens	DNA topoisomerase I	Inhibition	68.2	%	10.1016/j.bmc.2016.09.051
Homo sapiens	DNA topoisomerase I	Inhibition	68.3	%	10.1016/j.ejmech.2016.06.021
Homo sapiens	DNA topoisomerase I	Inhibition	68.8	%	10.1016/j.bmc.2010.03.051
Homo sapiens	DNA topoisomerase I	Inhibition	69.15	%	10.1016/j.ejmech.2011.01.011
Homo sapiens	DNA topoisomerase I	Inhibition	69.9	%	10.1016/j.ejmech.2016.09.004
Homo sapiens	DNA topoisomerase I	Inhibition	70.5	%	10.1016/j.bmcl.2013.03.106
Homo sapiens	DNA topoisomerase I	Inhibition	70.9	%	10.1016/j.ejmech.2015.08.040
Homo sapiens	DNA topoisomerase I	Inhibition	71.9	%	10.1016/j.ejmech.2013.08.040
Homo sapiens	DNA topoisomerase I	Inhibition	73.6	%	10.1016/j.bmc.2016.03.017
Homo sapiens	DNA topoisomerase I	Inhibition	74.0	%	10.1016/j.ejmech.2014.05.047
Homo sapiens	DNA topoisomerase I	Inhibition	74.32	%	10.1016/j.bmcl.2019.126714
Homo sapiens	DNA topoisomerase I	Inhibition	74.5	%	10.1016/j.bmc.2018.09.021
Homo sapiens	DNA topoisomerase I	Inhibition	74.7	%	10.1016/j.ejmech.2021.113916
Homo sapiens	DNA topoisomerase I	Inhibition	75.3	%	10.1016/j.bmc.2010.01.065
Homo sapiens	DNA topoisomerase I	Inhibition	75.5	%	10.1016/j.bmc.2009.12.069
Homo sapiens	DNA topoisomerase I	Inhibition	76.0	%	10.1016/j.bmc.2021.116177
Homo sapiens	DNA topoisomerase I	Inhibition	76.0	%	10.1016/j.bmcl.2021.128517
Homo sapiens	DNA topoisomerase I	Inhibition	76.0	%	10.1016/j.ejmech.2019.06.032
Homo sapiens	DNA topoisomerase I	Inhibition	77.0	%	10.1016/j.bmc.2006.12.012
Homo sapiens	DNA topoisomerase I	Inhibition	78.3	%	10.1016/j.bmc.2009.12.069
Homo sapiens	DNA topoisomerase I	Inhibition	79.0	%	10.1016/j.bmc.2009.10.049
Homo sapiens	DNA topoisomerase I	Inhibition	79.5	%	10.1016/j.ejmech.2016.12.035
Homo sapiens	DNA topoisomerase I	Inhibition	79.9	%	10.1016/j.bmc.2018.02.035
Homo sapiens	DNA topoisomerase I	Inhibition	80.0	%	10.1016/j.bmc.2021.116177
Homo sapiens	DNA topoisomerase I	Inhibition	80.0	%	10.1016/j.bmcl.2021.128517
Homo sapiens	DNA topoisomerase I	Inhibition	80.0	%	10.1016/j.ejmech.2019.06.032
Homo sapiens	DNA topoisomerase I	Inhibition	80.2	%	10.1016/j.ejmech.2021.113960
Homo sapiens	DNA topoisomerase I	Inhibition	80.7	%	10.1016/j.bmc.2015.04.002
Homo sapiens	DNA topoisomerase I	Inhibition	83.9	%	10.1016/j.bmcl.2018.01.048
Homo sapiens	DNA topoisomerase I	Inhibition	84.5	%	10.1016/j.bmcl.2009.09.091
Homo sapiens	DNA topoisomerase I	Inhibition	85.0	%	10.1021/jm1005447
Homo sapiens	DNA topoisomerase I	Inhibition	86.2	%	10.1016/j.bmcl.2009.03.058
Homo sapiens	DNA topoisomerase I	Inhibition	86.8	%	10.1016/j.bmcl.2017.06.025
Homo sapiens	DNA topoisomerase I	Inhibition	89.43	%	10.1016/j.ejmech.2021.113960
Homo sapiens	DNA topoisomerase I	Inhibition	89.65	%	10.1016/j.ejmech.2021.113960
Homo sapiens	DNA topoisomerase I	Inhibition	91.38	%	10.1016/j.bmc.2022.116723
Homo sapiens	DNA topoisomerase I	Inhibition	94.25	%	10.1021/acs.jmedchem.2c00520
Homo sapiens	DNA topoisomerase I	Inhibition	94.38	%	10.1021/acs.jmedchem.2c00520
Homo sapiens	DNA topoisomerase I	Inhibition	95.0	%	10.1016/j.bmc.2012.05.030
Homo sapiens	DNA topoisomerase I	Inhibition	95.0	%	10.1021/jm101338z
Homo sapiens	DNA topoisomerase I	Inhibition	100.0	%	10.1016/S0960-894X(01)80158-X
Homo sapiens	DNA topoisomerase I	Inhibition	100.0	uM	10.1021/jm051247f
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2009.08.066
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2010.04.085
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2012.05.030
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2013.06.033
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2013.07.016
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2013.09.006
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2013.09.030
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2015.07.020
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2016.09.034
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2018.06.016
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2019.05.016
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmc.2022.116723
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2012.12.063
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2014.01.049
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2015.04.011
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2015.06.042
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2016.09.062
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2017.03.039
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2020.127051
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2021.127954
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2021.127998
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.bmcl.2023.129305
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2009.04.012
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2011.02.065
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2011.04.059
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2012.03.011
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2012.05.002
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2012.10.051
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2013.02.026
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2013.08.038
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2014.09.016
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2014.09.021
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2014.09.050
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2014.09.079
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2015.07.007
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2015.08.032
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2016.06.021
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2016.06.024
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2016.06.054
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2016.12.035
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2017.07.027
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2017.07.050
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2018.01.010
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2018.10.065
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2020.112292
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1016/j.ejmech.2021.113916
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.0c00727
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.1c00318
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.1c01362
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.1c01411
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.2c00615
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.5b00303
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.6b01565
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.6b01870
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.7b01297
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.8b00498
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.8b00639
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acs.jmedchem.8b01938
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/acsmedchemlett.6b00242
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm100387d
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm1009428
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm200719v
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm201512x
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm300605m
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm400932c
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm401471v
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm5003588
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm900469e
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm901649x
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/jm9605445
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/ml500327q
Homo sapiens	DNA topoisomerase I	Inhibition	nan	%	10.1021/np900312u
Homo sapiens	DNA topoisomerase I	K app	0.14	1/min	10.1016/j.bmcl.2004.08.010
Homo sapiens	DNA topoisomerase I	MIC	10.0	nM	10.1021/jm00075a025
Homo sapiens	DNA topoisomerase I	Ratio	0.39	None	10.1021/jm970765q
Homo sapiens	DNA topoisomerase I	REC	0.5	None	10.1021/jm020498a
Homo sapiens	DNA topoisomerase I	REC	1.0	None	10.1016/j.bmcl.2004.08.070
Homo sapiens	DNA topoisomerase I	Relaxed DNA	64.0	%	10.1021/jm980400l
Homo sapiens	DNA topoisomerase I	Stimulation	8.2	None	10.1021/jm000129j
Homo sapiens	DNA topoisomerase II	Inhibition	nan	%	10.1021/jm051247f
Homo sapiens	DNA topoisomerase II alpha	Activity	nan	None	10.1016/j.bmc.2010.10.054
Homo sapiens	DNA topoisomerase II alpha	FC	nan	None	10.1016/j.bmc.2013.11.034
Homo sapiens	DNA topoisomerase II alpha	IC50	300000.0	nM	10.1021/np0004606
Homo sapiens	DNA topoisomerase II alpha	Inhibition	30.0	%	10.1016/j.bmc.2016.09.051
Homo sapiens	DNA topoisomerase II alpha	Inhibition	40.0	%	10.1016/j.bmc.2009.11.048
Homo sapiens	DNA topoisomerase II alpha	Inhibition	70.16	%	10.1021/acs.jmedchem.2c00520
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.bmc.2016.09.051
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.bmc.2018.09.019
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.bmcl.2007.12.053
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.bmcl.2009.09.091
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.ejmech.2009.04.012
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.ejmech.2016.09.004
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.ejmech.2016.09.019
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1016/j.ejmech.2017.11.011
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1021/jm5003588
Homo sapiens	DNA topoisomerase II alpha	Inhibition	nan	%	10.1021/np900312u
Homo sapiens	DNA topoisomerase II beta	MIC	100000.0	nM	10.1021/jm00075a025
Homo sapiens	DOHH-2	IC50	0.6022	nM	10.6019/CHEMBL1201861
Homo sapiens	DOK	IC50	18.92	nM	10.6019/CHEMBL1201861
Homo sapiens	Dopamine D1 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D1 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D2 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D2 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D3 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D3 receptor	Ki	nan	None	None
Homo sapiens	Dopamine D4 receptor	IC50	nan	None	None
Homo sapiens	Dopamine D4 receptor	Ki	nan	None	None
Homo sapiens	Dopamine transporter	IC50	nan	None	None
Homo sapiens	Dopamine transporter	Ki	nan	None	None
Homo sapiens	DoTc2-4510	IC50	4.032	nM	10.6019/CHEMBL1201861
Homo sapiens	dsDNA	deltaTm	nan	None	10.1021/acs.jmedchem.8b00639
Homo sapiens	DSH1	IC50	15.75	nM	10.6019/CHEMBL1201861
Homo sapiens	DU-145	CC50	15.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	DU-145	CC50	80.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	DU-145	ED50	10.9	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	DU-145	GI50	10.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	DU-145	GI50	10.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	DU-145	GI50	10.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm000029d
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm040025z
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm060046o
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm0613119
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm070307+
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm070361q
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm101338z
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm200719v
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm201512x
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm401471v
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm500294a
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm800259e
Homo sapiens	DU-145	GI50	10.0	nM	10.1021/jm901649x
Homo sapiens	DU-145	GI50	10.0	nM	None
Homo sapiens	DU-145	GI50	18.2	nM	10.1021/jm401471v
Homo sapiens	DU-145	GI50	19.0	nM	10.1016/j.ejmech.2018.04.040
Homo sapiens	DU-145	GI50	21.0	nM	10.1021/acs.jmedchem.8b00639
Homo sapiens	DU-145	GI50	210.0	nM	10.1016/j.ejmech.2019.05.074
Homo sapiens	DU-145	GI50	210.0	nM	10.1021/acs.jmedchem.1c00318
Homo sapiens	DU-145	IC50	10.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	DU-145	IC50	15.0	nM	10.1021/np2009219
Homo sapiens	DU-145	IC50	16.0	nM	10.1021/acs.jnatprod.8b00430
Homo sapiens	DU-145	IC50	20.0	nM	10.1016/j.bmc.2010.10.042
Homo sapiens	DU-145	IC50	20.0	nM	10.1016/j.bmc.2015.04.002
Homo sapiens	DU-145	IC50	28.7	nM	10.1016/j.bmcl.2012.10.002
Homo sapiens	DU-145	IC50	29.0	nM	10.1021/jm5003588
Homo sapiens	DU-145	IC50	50.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	DU-145	IC50	70.0	nM	10.1016/j.ejmech.2020.112844
Homo sapiens	DU-145	IC50	100.0	nM	10.1016/j.ejmech.2014.09.050
Homo sapiens	DU-145	IC50	110.0	nM	10.1016/j.bmc.2014.11.010
Homo sapiens	DU-145	IC50	110.0	nM	10.1016/j.bmc.2015.08.018
Homo sapiens	DU-145	IC50	210.0	nM	10.1016/j.ejmech.2021.113916
Homo sapiens	DU-145	IC50	310.0	nM	10.1016/j.ejmech.2011.01.011
Homo sapiens	DU-145	IC50	390.0	nM	10.1016/j.ejmech.2013.07.048
Homo sapiens	DU-145	IC50	400.0	nM	10.1016/j.bmc.2010.03.051
Homo sapiens	DU-145	IC50	400.0	nM	10.1016/j.bmc.2015.04.031
Homo sapiens	DU-145	IC50	400.0	nM	10.1016/j.ejmech.2011.04.029
Homo sapiens	DU-145	IC50	610.0	nM	10.1016/j.bmcl.2010.11.037
Homo sapiens	DU-145	IC50	660.0	nM	10.1016/j.bmc.2009.10.049
Homo sapiens	DU-145	IC50	800.0	nM	10.1021/np400545v
Homo sapiens	DU-145	IC50	940.0	nM	10.1016/j.bmc.2010.01.065
Homo sapiens	DU-145	IC50	950.0	nM	10.1016/j.ejmech.2014.07.058
Homo sapiens	DU-145	IC50	1000.0	nM	10.1016/j.bmcl.2009.09.091
Homo sapiens	DU-145	IC50	1060.0	nM	10.1016/j.ejmech.2012.03.010
Homo sapiens	DU-145	IC50	1460.0	nM	10.1016/j.bmcl.2009.11.041
Homo sapiens	DU-145	IC50	1990.0	nM	10.1016/j.ejmech.2020.112327
Homo sapiens	DU-145	IC50	2281.94	nM	10.6019/CHEMBL1201861
Homo sapiens	DU-145	IC50	2370.0	nM	10.1016/j.ejmech.2012.01.015
Homo sapiens	DU-145	IC50	3200.0	nM	10.1016/j.bmcl.2007.12.053
Homo sapiens	DU-145	IC50	3200.0	nM	10.1016/j.ejmech.2010.06.017
Homo sapiens	DU-145	IC50	3570.0	nM	10.1016/j.bmc.2009.12.069
Homo sapiens	DU-145	IC50	4010.0	nM	10.1016/j.ejmech.2014.05.047
Homo sapiens	DU-145	IC50	9290.0	nM	10.1016/j.bmc.2012.06.034
Homo sapiens	DU-145	Inhibition	69.4	%	10.1016/j.bmc.2009.09.014
Homo sapiens	DU-145	RatioGI50	54.85	None	10.1021/jm401471v
Homo sapiens	DU-4475	IC50	3.067	nM	10.6019/CHEMBL1201861
Homo sapiens	ECC10	IC50	3.853	nM	10.6019/CHEMBL1201861
Homo sapiens	EC-GI-10	IC50	7.904	nM	10.6019/CHEMBL1201861
Homo sapiens	EFM-19	IC50	126.89	nM	10.6019/CHEMBL1201861
Homo sapiens	EFO-21	IC50	20.32	nM	10.6019/CHEMBL1201861
Homo sapiens	EFO-27	IC50	80.99	nM	10.6019/CHEMBL1201861
Homo sapiens	EGI-1	IC50	25.07	nM	10.6019/CHEMBL1201861
Homo sapiens	EKVX	GI50	95.06	nM	None
Homo sapiens	EKVX	IC50	436.37	nM	10.6019/CHEMBL1201861
Homo sapiens	EM-2	IC50	4.08	nM	10.6019/CHEMBL1201861
Homo sapiens	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Potency	3162.3	nM	None
Homo sapiens	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Potency	3981.1	nM	None
Homo sapiens	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Potency	7943.3	nM	None
Homo sapiens	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Potency	10000.0	nM	None
Homo sapiens	Endothelin receptor ET-A	IC50	nan	None	None
Homo sapiens	Endothelin receptor ET-A	Ki	nan	None	None
Homo sapiens	EOL1	IC50	0.2708	nM	10.6019/CHEMBL1201861
Homo sapiens	Epidermal growth factor receptor erbB1	IC50	nan	None	None
Homo sapiens	Epidermal growth factor receptor erbB1	Ki	nan	None	None
Homo sapiens	EPLC-272H	IC50	72.8	nM	10.6019/CHEMBL1201861
Homo sapiens	ES1	IC50	0.09574	nM	10.6019/CHEMBL1201861
Homo sapiens	ES3	IC50	0.9311	nM	10.6019/CHEMBL1201861
Homo sapiens	ES4	IC50	1.474	nM	10.6019/CHEMBL1201861
Homo sapiens	ES5	IC50	0.7735	nM	10.6019/CHEMBL1201861
Homo sapiens	ES6	IC50	88.05	nM	10.6019/CHEMBL1201861
Homo sapiens	ES7	IC50	0.02543	nM	10.6019/CHEMBL1201861
Homo sapiens	ES8	IC50	0.7956	nM	10.6019/CHEMBL1201861
Homo sapiens	ESS-1	IC50	7.079	nM	10.6019/CHEMBL1201861
Homo sapiens	Estrogen receptor alpha	IC50	nan	None	None
Homo sapiens	Estrogen receptor alpha	Ki	nan	None	None
Homo sapiens	Estrogen receptor beta	IC50	nan	None	None
Homo sapiens	Estrogen receptor beta	Ki	nan	None	None
Homo sapiens	ETK-1	IC50	34.89	nM	10.6019/CHEMBL1201861
Homo sapiens	Eukaryotic translation initiation factor 2-alpha kinase 3	EC50	55700.0	nM	None
Homo sapiens	EVSA-T	ID50	3.2	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	EW-1	IC50	1.777	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-11	IC50	2.659	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-13	IC50	3.267	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-16	IC50	0.1214	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-18	IC50	150.08	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-22	IC50	0.5566	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-24	IC50	4.033	nM	10.6019/CHEMBL1201861
Homo sapiens	EW-3	IC50	0.3192	nM	10.6019/CHEMBL1201861
Homo sapiens	FaDu	IC50	0.5392	nM	10.6019/CHEMBL1201861
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	52.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	65.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	58.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	231110.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	44.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	99.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	211.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	230.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	242.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Growth Rate	-0.02	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.11	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	1.0	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Population Apoptotic (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	66.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	72.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	78.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	92.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	100.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	39.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	41.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	42.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	64.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	65.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	66.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	35.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	39.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	46.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	48.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	41.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	42.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	44.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	46.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	52.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	56.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	67.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	38.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	100.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	52.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	54.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	58.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	64.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	71.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	72.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	23.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	74.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	77.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	83.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	89.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	94.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	95.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	97.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	100.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	147.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	151.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	176.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	198.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	201.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	222.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	225.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	250.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	256.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	296.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	303.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	326.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	382.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	405.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	414.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	440.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast growth factor receptor 3	Delta TM	0.01	C	None
Homo sapiens	FTC-133	IC50	4.567	nM	10.6019/CHEMBL1201861
Homo sapiens	G-361	IC50	2544.45	nM	10.6019/CHEMBL1201861
Homo sapiens	G-401	IC50	19.16	nM	10.6019/CHEMBL1201861
Homo sapiens	G-402	IC50	24.5	nM	10.6019/CHEMBL1201861
Homo sapiens	GAK	IC50	218.07	nM	10.6019/CHEMBL1201861
Homo sapiens	GAMG	IC50	1.527	nM	10.6019/CHEMBL1201861
Homo sapiens	GB-1	IC50	4.677	nM	10.6019/CHEMBL1201861
Homo sapiens	GCIY	IC50	66.15	nM	10.6019/CHEMBL1201861
Homo sapiens	GCT	IC50	5.023	nM	10.6019/CHEMBL1201861
Homo sapiens	Geminin	Potency	316.2	nM	None
Homo sapiens	Geminin	Potency	7307.8	nM	None
Homo sapiens	GI-1	IC50	3.365	nM	10.6019/CHEMBL1201861
Homo sapiens	GI-ME-N	IC50	33.89	nM	10.6019/CHEMBL1201861
Homo sapiens	Glucocorticoid receptor	IC50	nan	None	None
Homo sapiens	Glucocorticoid receptor	Ki	nan	None	None
Homo sapiens	Glycogen synthase kinase-3 beta	Delta TM	-0.26	C	None
Homo sapiens	GMS-10	IC50	7.311	nM	10.6019/CHEMBL1201861
Homo sapiens	GOTO	IC50	0.7058	nM	10.6019/CHEMBL1201861
Homo sapiens	GP5d	IC50	12.49	nM	10.6019/CHEMBL1201861
Homo sapiens	GR-ST	IC50	0.701	nM	10.6019/CHEMBL1201861
Homo sapiens	GT3TKB	IC50	1.759	nM	10.6019/CHEMBL1201861
Homo sapiens	H4	IC50	0.6154	nM	10.6019/CHEMBL1201861
Homo sapiens	H69AR	IC50	300.0	nM	10.1021/jm101354u
Homo sapiens	H9	IC50	0.3582	nM	10.6019/CHEMBL1201861
Homo sapiens	HAL-01	IC50	2.551	nM	10.6019/CHEMBL1201861
Homo sapiens	HBL-100	GI50	230.0	nM	10.1016/j.bmc.2009.07.053
Homo sapiens	HBL-100	GI50	230.0	nM	10.1016/j.ejmech.2013.06.013
Homo sapiens	HC-1	IC50	3.344	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1187	IC50	314.07	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1395	IC50	1367.35	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1419	IC50	4155.69	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1569	IC50	267.54	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1806	IC50	3.143	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1937	IC50	349.21	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC1954	IC50	266.61	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC2218	IC50	55.5	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC 2998	GI50	158.85	nM	None
Homo sapiens	HCC 2998	IC50	150.28	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC38	IC50	12.86	nM	10.6019/CHEMBL1201861
Homo sapiens	HCC70	IC50	44.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	HCC70	IC50	45.46	nM	10.6019/CHEMBL1201861
Homo sapiens	HCCLM9	IC50	150000.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	HCE-4	IC50	1.814	nM	10.6019/CHEMBL1201861
Homo sapiens	HCE-T	IC50	5.469	nM	10.6019/CHEMBL1201861
Homo sapiens	HCT-116	Activity	-30.0	%	10.1016/j.ejmech.2017.09.005
Homo sapiens	HCT-116	Activity	1.6	%	10.1016/j.ejmech.2016.09.065
Homo sapiens	HCT-116	Activity	1.6	%	10.1016/j.ejmech.2017.09.005
Homo sapiens	HCT-116	Activity	5.07	%	10.1016/j.ejmech.2016.09.065
Homo sapiens	HCT-116	Activity	5.07	%	10.1016/j.ejmech.2017.09.005
Homo sapiens	HCT-116	Activity	5.08	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	5.73	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	7.33	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	10.06	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	12.44	%	10.1016/j.ejmech.2016.09.065
Homo sapiens	HCT-116	Activity	12.44	%	10.1016/j.ejmech.2017.09.005
Homo sapiens	HCT-116	Activity	24.52	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	27.71	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	36.77	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	40.9	%	10.1021/jm401471v
Homo sapiens	HCT-116	Activity	80.88	%	10.1016/j.ejmech.2016.09.065
Homo sapiens	HCT-116	Activity	80.88	%	10.1016/j.ejmech.2017.09.005
Homo sapiens	HCT-116	Activity	81.86	%	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	nan	None	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	Activity	nan	None	10.1016/j.ejmech.2016.09.065
Homo sapiens	HCT-116	Activity	nan	None	10.1021/acs.jmedchem.2c00432
Homo sapiens	HCT-116	GI50	9.0	nM	10.1016/j.ejmech.2018.04.040
Homo sapiens	HCT-116	GI50	9.0	nM	10.1016/j.ejmech.2019.05.074
Homo sapiens	HCT-116	GI50	9.0	nM	10.1021/acs.jmedchem.8b00639
Homo sapiens	HCT-116	GI50	17.38	nM	10.1021/jm401471v
Homo sapiens	HCT-116	GI50	23.01	nM	None
Homo sapiens	HCT-116	GI50	30.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	HCT-116	GI50	30.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	HCT-116	GI50	30.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm000029d
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm040025z
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm060046o
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm0613119
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm070307+
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm070361q
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm101338z
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm200719v
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm201512x
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm401471v
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm500294a
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm800259e
Homo sapiens	HCT-116	GI50	30.0	nM	10.1021/jm901649x
Homo sapiens	HCT-116	GI50	35.48	nM	10.1021/jm401471v
Homo sapiens	HCT-116	GI50	50.0	nM	10.1021/acs.jmedchem.1c00318
Homo sapiens	HCT-116	GI50	50.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	HCT-116	GI50	75.0	nM	10.1016/j.ejmech.2018.04.040
Homo sapiens	HCT-116	GI50	75.0	nM	10.1016/j.ejmech.2019.05.074
Homo sapiens	HCT-116	GI50	75.0	nM	10.1021/acs.jmedchem.8b00639
Homo sapiens	HCT-116	GI50	83.0	nM	10.1021/jm300605m
Homo sapiens	HCT-116	GI50	195.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	HCT-116	IC50	2.0	nM	10.1021/jm900365v
Homo sapiens	HCT-116	IC50	2.01	nM	10.1016/j.ejmech.2022.114438
Homo sapiens	HCT-116	IC50	5.051	nM	10.6019/CHEMBL1201861
Homo sapiens	HCT-116	IC50	8.5	nM	10.1039/C9MD00305C
Homo sapiens	HCT-116	IC50	9.0	nM	10.1021/acsmedchemlett.9b00513
Homo sapiens	HCT-116	IC50	9.0	nM	10.1021/np010459m
Homo sapiens	HCT-116	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	HCT-116	IC50	11.5	nM	10.1016/j.bmcl.2017.04.057
Homo sapiens	HCT-116	IC50	13.0	nM	10.1021/acs.jnatprod.8b00430
Homo sapiens	HCT-116	IC50	16.0	nM	10.1021/np400460m
Homo sapiens	HCT-116	IC50	17.0	nM	10.1016/j.ejmech.2021.113544
Homo sapiens	HCT-116	IC50	20.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	HCT-116	IC50	22.9	nM	10.1016/j.ejmech.2012.05.002
Homo sapiens	HCT-116	IC50	30.0	nM	10.1016/j.ejmech.2019.111700
Homo sapiens	HCT-116	IC50	40.0	nM	10.1016/j.bmc.2022.116793
Homo sapiens	HCT-116	IC50	40.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	HCT-116	IC50	50.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	HCT-116	IC50	70.0	nM	10.1021/jm400906z
Homo sapiens	HCT-116	IC50	90.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	HCT-116	IC50	90.0	nM	10.1021/acs.jmedchem.5b00910
Homo sapiens	HCT-116	IC50	100.0	nM	10.1021/jm3001532
Homo sapiens	HCT-116	IC50	110.0	nM	10.1016/j.ejmech.2012.07.050
Homo sapiens	HCT-116	IC50	120.0	nM	10.1016/j.bmcl.2017.03.039
Homo sapiens	HCT-116	IC50	130.0	nM	10.1021/np900312u
Homo sapiens	HCT-116	IC50	159.0	nM	10.1016/j.ejmech.2016.05.065
Homo sapiens	HCT-116	IC50	159.0	nM	10.1016/j.ejmech.2017.04.071
Homo sapiens	HCT-116	IC50	250.0	nM	10.1016/j.ejmech.2020.112870
Homo sapiens	HCT-116	IC50	400.0	nM	10.1016/j.ejmech.2020.112509
Homo sapiens	HCT-116	IC50	600.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	HCT-116	IC50	1000.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	HCT-116	IC50	1000.0	nM	10.1016/j.bmcl.2007.12.053
Homo sapiens	HCT-116	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	HCT-116	IC50	1880.0	nM	10.1016/j.bmcl.2018.10.014
Homo sapiens	HCT-116	IC50	1880.0	nM	10.1016/j.ejmech.2017.09.005
Homo sapiens	HCT-116	IC50	2300.0	nM	10.1016/j.ejmech.2010.06.017
Homo sapiens	HCT-116	IC50	2770.0	nM	10.1016/j.bmcl.2009.11.041
Homo sapiens	HCT-116	IC50	3970.0	nM	10.1016/j.ejmech.2011.01.011
Homo sapiens	HCT-116	IC50	nan	None	10.1021/acs.jnatprod.6b00782
Homo sapiens	HCT-116	ID50	2.8	nM	10.1016/s0960-894x(02)00153-1
Homo sapiens	HCT-116	Ratio	0.32	None	10.1016/j.ejmech.2020.112870
Homo sapiens	HCT-116	Ratio	0.64	None	10.1016/j.ejmech.2013.04.017
Homo sapiens	HCT-116	Ratio	8.3	None	10.1016/j.ejmech.2019.05.074
Homo sapiens	HCT-116	RatioGI50	2.04	None	10.1021/jm401471v
Homo sapiens	HCT-116	TD50	0.006	ug ml-1	10.1016/0960-894X(95)00538-5
Homo sapiens	HCT-116/VM46	ID50	2.4	nM	10.1016/s0960-894x(02)00153-1
Homo sapiens	HCT-15	Activity	0.089	ug ml-1	10.1016/j.bmcl.2009.03.042
Homo sapiens	HCT-15	Activity	nan	None	10.1021/np100429s
Homo sapiens	HCT-15	GI50	151.71	nM	None
Homo sapiens	HCT-15	IC50	0.096	ug.mL-1	10.1016/j.bmc.2011.05.012
Homo sapiens	HCT-15	IC50	3.0	nM	10.1021/jm900365v
Homo sapiens	HCT-15	IC50	18.0	nM	10.1021/jm051247f
Homo sapiens	HCT-15	IC50	20.0	nM	10.1016/j.bmc.2018.02.035
Homo sapiens	HCT-15	IC50	49.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	HCT-15	IC50	50.0	nM	10.1016/j.bmc.2018.09.021
Homo sapiens	HCT-15	IC50	50.0	nM	10.1016/j.bmcl.2018.01.048
Homo sapiens	HCT-15	IC50	67.0	nM	10.1016/j.bmc.2010.10.042
Homo sapiens	HCT-15	IC50	80.0	nM	10.1016/j.bmcl.2007.08.062
Homo sapiens	HCT-15	IC50	80.0	nM	10.1016/j.ejmech.2021.113916
Homo sapiens	HCT-15	IC50	83.0	nM	10.1016/j.ejmech.2007.05.002
Homo sapiens	HCT-15	IC50	166.0	nM	10.1016/j.bmc.2011.08.006
Homo sapiens	HCT-15	IC50	260.0	nM	10.1016/j.ejmech.2012.01.015
Homo sapiens	HCT-15	IC50	260.0	nM	10.1016/j.ejmech.2017.03.048
Homo sapiens	HCT-15	IC50	300.0	nM	10.1016/j.bmc.2015.08.018
Homo sapiens	HCT-15	IC50	420.0	nM	10.1016/j.ejmech.2013.07.048
Homo sapiens	HCT-15	IC50	500.0	nM	10.1016/j.bmc.2010.03.051
Homo sapiens	HCT-15	IC50	500.0	nM	10.1016/j.ejmech.2011.04.029
Homo sapiens	HCT-15	IC50	520.0	nM	10.1016/j.bmc.2015.04.031
Homo sapiens	HCT-15	IC50	600.0	nM	10.1016/j.ejmech.2017.01.003
Homo sapiens	HCT-15	IC50	640.0	nM	10.1016/j.bmc.2010.01.065
Homo sapiens	HCT-15	IC50	760.0	nM	10.1016/j.bmc.2009.10.049
Homo sapiens	HCT-15	IC50	760.0	nM	10.1016/j.bmcl.2017.06.025
Homo sapiens	HCT-15	IC50	776.97	nM	10.6019/CHEMBL1201861
Homo sapiens	HCT-15	IC50	800.0	nM	10.1016/j.bmcl.2010.11.037
Homo sapiens	HCT-15	IC50	1380.0	nM	10.1016/j.ejmech.2012.03.010
Homo sapiens	HCT-15	IC50	1590.0	nM	10.1016/j.ejmech.2020.112327
Homo sapiens	HCT-15	IC50	2820.0	nM	10.1016/j.bmc.2015.04.002
Homo sapiens	HCT-15	IC50	6080.0	nM	10.1016/j.ejmech.2015.08.040
Homo sapiens	HCT-15	IC50	9920.0	nM	10.1016/j.bmc.2012.06.034
Homo sapiens	HCT-15	IC50	nan	nM	10.1016/j.bmcl.2003.09.001
Homo sapiens	HCT-15	IC50	nan	None	10.1021/acs.jnatprod.6b00782
Homo sapiens	HCT-8	IC50	0.005	ug.mL-1	10.1016/j.bmcl.2004.05.032
Homo sapiens	HCT-8	IC50	7.0	nM	10.1016/j.bmcl.2003.08.012
Homo sapiens	HCT-8	IC50	13.0	nM	10.1016/j.ejmech.2010.03.013
Homo sapiens	HCT-8	IC50	24.0	nM	10.1016/j.ejmech.2016.11.013
Homo sapiens	HCT-8	IC50	260.0	nM	10.1021/np200706n
Homo sapiens	HCT-8	IC50	3150.0	nM	10.1021/np0703794
Homo sapiens	HCT-8	IC50	3200.0	nM	10.1021/np800576s
Homo sapiens	HDLM-2	IC50	486.07	nM	10.6019/CHEMBL1201861
Homo sapiens	HD-MY-Z	IC50	1.634	nM	10.6019/CHEMBL1201861
Homo sapiens	HEC-1	IC50	18.13	nM	10.6019/CHEMBL1201861
Homo sapiens	HEC-1B cell line	IC50	60.0	nM	10.1016/s0960-894x(99)00555-7
Homo sapiens	HEC-1B cell line	IC50	8640.0	nM	10.1016/s0960-894x(02)01041-7
Homo sapiens	HEK293	Activity	nan	None	10.1016/j.bmc.2015.12.020
Homo sapiens	HEK293	IC50	0.56	nM	10.1016/j.ejmech.2018.02.058
Homo sapiens	HEK293	IC50	5.6	nM	10.1016/j.bmcl.2021.128517
Homo sapiens	HEK293	IC50	10.0	nM	10.1016/j.bmcl.2016.12.043
Homo sapiens	HEK293	IC50	280.0	nM	10.1016/j.ejmech.2014.07.058
Homo sapiens	HEK293	IC50	600.0	nM	10.1016/j.ejmech.2020.112509
Homo sapiens	HEK293	IC50	780.0	nM	10.1016/j.ejmech.2013.07.048
Homo sapiens	HEK293	IC50	1010.0	nM	10.1016/j.ejmech.2012.03.010
Homo sapiens	HEK293	IC50	1610.0	nM	10.1016/j.bmcl.2018.10.014
Homo sapiens	HEK293	IC50	7940.0	nM	10.1016/j.bmc.2012.06.034
Homo sapiens	HEK293	IC50	8750.0	nM	10.1016/j.ejmech.2020.112551
Homo sapiens	HEK293	IC50	54690.0	nM	10.1016/j.ejmech.2017.09.009
Homo sapiens	HEK293	IC50	nan	None	10.1016/j.ejmech.2021.113330
Homo sapiens	HEK293	IC50	nan	None	10.1021/acs.jmedchem.1c01411
Homo sapiens	HEK293	Potency	44.7	nM	None
Homo sapiens	HEK293	Potency	82.0	nM	None
Homo sapiens	HEK-293T	Activity	nan	None	10.1021/acs.jmedchem.0c00894
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	23.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Growth Rate	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Growth Rate	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	73.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	691.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	838.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	865.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	1080.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	1765.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	3025.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Growth Rate	-0.84	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	-0.29	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.41	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.65	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.83	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.88	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	IC50	30.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	HEK-293T	IC50	690.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	HEK-293T	IC50	5650.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	HEK-293T	IC50	nan	None	10.1016/j.ejmech.2015.03.033
Homo sapiens	HEK-293T	Population Apoptotic (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	23.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	44.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	44.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	51.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	60.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	73.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	75.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	76.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	78.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	93.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	94.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	66.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	70.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	73.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	76.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	100.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	66.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	71.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	73.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	79.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	92.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	94.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	95.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	96.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	97.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	98.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	575.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	653.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	665.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	710.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	837.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	853.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	854.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	862.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	886.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	890.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	915.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	952.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	993.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1137.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1177.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1218.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1427.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1448.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1582.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1627.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1694.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1706.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1781.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1821.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEL	IC50	6.311	nM	10.6019/CHEMBL1201861
Homo sapiens	HeLa	Activity	3.0	%	10.1016/j.ejmech.2018.01.020
Homo sapiens	HeLa	Activity	17.7	%	10.1016/j.ejmech.2012.12.017
Homo sapiens	HeLa	Activity	29.0	%	10.1016/j.ejmech.2018.01.020
Homo sapiens	HeLa	Activity	33.1	%	10.1039/C2MD20098H
Homo sapiens	HeLa	Activity	68.6	%	10.1016/j.ejmech.2012.12.017
Homo sapiens	HeLa	Activity	nan	None	10.1016/j.bmcl.2009.05.037
Homo sapiens	HeLa	Activity	nan	None	10.1016/j.ejmech.2012.02.032
Homo sapiens	HeLa	Activity	nan	None	10.1016/j.ejmech.2014.06.050
Homo sapiens	HeLa	Concentration	0.1	uM	10.1016/j.bmcl.2004.01.060
Homo sapiens	HeLa	ED50	0.19	ug ml-1	10.1021/np078016r
Homo sapiens	HeLa	GI50	10.0	nM	10.1016/j.bmc.2007.03.067
Homo sapiens	HeLa	GI50	40.0	nM	10.1021/jm900469e
Homo sapiens	HeLa	GI50	50.0	nM	10.1016/j.bmc.2012.12.026
Homo sapiens	HeLa	GI50	80.0	nM	10.1021/jm1005447
Homo sapiens	HeLa	GI50	180.0	nM	10.1016/j.bmc.2007.12.028
Homo sapiens	HeLa	GI50	190.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	HeLa	GI50	600.0	nM	10.1016/j.bmcl.2004.01.060
Homo sapiens	HeLa	GI50	600.0	nM	10.1016/j.ejmech.2013.06.013
Homo sapiens	HeLa	GI50	1300.0	nM	10.1016/j.bmc.2009.07.053
Homo sapiens	HeLa	GI50	1300.0	nM	10.1021/jm1009428
Homo sapiens	HeLa	IC50	0.19	ug.mL-1	10.1021/np800126f
Homo sapiens	HeLa	IC50	0.28	ug.mL-1	10.1007/s00044-010-9381-7
Homo sapiens	HeLa	IC50	8.9	nM	10.1016/j.bmc.2010.09.069
Homo sapiens	HeLa	IC50	24.0	nM	10.1021/ml400125z
Homo sapiens	HeLa	IC50	60.0	nM	10.1016/j.ejmech.2017.03.048
Homo sapiens	HeLa	IC50	72.0	nM	10.1016/j.bmcl.2009.03.058
Homo sapiens	HeLa	IC50	80.0	nM	10.1021/acs.jnatprod.6b01019
Homo sapiens	HeLa	IC50	90.0	nM	10.1016/j.ejmech.2017.01.003
Homo sapiens	HeLa	IC50	117.2	nM	10.1016/j.bmcl.2004.08.010
Homo sapiens	HeLa	IC50	120.0	nM	10.1021/acs.jnatprod.5b00828
Homo sapiens	HeLa	IC50	130.0	nM	10.1016/j.bmc.2018.02.035
Homo sapiens	HeLa	IC50	130.0	nM	10.1021/np4007074
Homo sapiens	HeLa	IC50	180.0	nM	10.1016/j.bmc.2015.04.002
Homo sapiens	HeLa	IC50	180.0	nM	10.1016/j.ejmech.2016.02.050
Homo sapiens	HeLa	IC50	180.0	nM	10.1039/C4MD00133H
Homo sapiens	HeLa	IC50	200.0	nM	10.1021/jm900469e
Homo sapiens	HeLa	IC50	230.0	nM	10.1016/j.ejmech.2021.113916
Homo sapiens	HeLa	IC50	400.0	nM	10.1016/j.bmc.2010.03.051
Homo sapiens	HeLa	IC50	400.0	nM	10.1016/j.bmc.2014.11.010
Homo sapiens	HeLa	IC50	400.0	nM	10.1016/j.ejmech.2011.04.029
Homo sapiens	HeLa	IC50	400.0	nM	10.1016/j.ejmech.2012.02.032
Homo sapiens	HeLa	IC50	400.0	nM	10.1016/j.ejmech.2012.10.034
Homo sapiens	HeLa	IC50	410.0	nM	10.1016/j.bmc.2015.04.031
Homo sapiens	HeLa	IC50	420.0	nM	10.1016/j.ejmech.2014.06.050
Homo sapiens	HeLa	IC50	500.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	HeLa	IC50	500.0	nM	10.1021/np0603976
Homo sapiens	HeLa	IC50	500.0	nM	10.1021/np400545v
Homo sapiens	HeLa	IC50	580.0	nM	10.1016/j.bmcl.2009.09.091
Homo sapiens	HeLa	IC50	590.0	nM	10.1016/j.bmcl.2016.02.053
Homo sapiens	HeLa	IC50	630.0	nM	10.1016/j.bmc.2009.10.049
Homo sapiens	HeLa	IC50	630.0	nM	10.1016/j.bmc.2010.01.065
Homo sapiens	HeLa	IC50	660.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	HeLa	IC50	860.0	nM	10.1016/j.bmc.2009.12.069
Homo sapiens	HeLa	IC50	940.0	nM	10.1016/j.bmcl.2010.03.048
Homo sapiens	HeLa	IC50	940.0	nM	10.1016/j.ejmech.2018.01.020
Homo sapiens	HeLa	IC50	1010.0	nM	10.1016/j.ejmech.2012.01.015
Homo sapiens	HeLa	IC50	1080.0	nM	10.1016/j.bmcl.2007.12.053
Homo sapiens	HeLa	IC50	1080.0	nM	10.1016/j.ejmech.2011.01.011
Homo sapiens	HeLa	IC50	1100.0	nM	10.1016/j.ejmech.2010.06.017
Homo sapiens	HeLa	IC50	1220.0	nM	10.1021/np900077h
Homo sapiens	HeLa	IC50	1300.0	nM	10.1016/j.bmc.2018.07.001
Homo sapiens	HeLa	IC50	1370.0	nM	10.1016/j.bmc.2018.09.021
Homo sapiens	HeLa	IC50	1370.0	nM	10.1016/j.bmcl.2018.01.048
Homo sapiens	HeLa	IC50	1500.0	nM	10.1016/j.ejmech.2010.11.046
Homo sapiens	HeLa	IC50	1570.0	nM	10.1016/j.ejmech.2012.02.032
Homo sapiens	HeLa	IC50	1570.0	nM	10.1016/j.ejmech.2012.10.034
Homo sapiens	HeLa	IC50	1590.0	nM	10.1016/j.ejmech.2015.08.040
Homo sapiens	HeLa	IC50	1660.0	nM	10.1016/j.ejmech.2020.112768
Homo sapiens	HeLa	IC50	1850.0	nM	10.1016/j.bmcl.2009.11.041
Homo sapiens	HeLa	IC50	2620.0	nM	10.1016/j.bmcl.2017.06.025
Homo sapiens	HeLa	IC50	3800.0	nM	10.1016/j.bmc.2017.04.030
Homo sapiens	HeLa	IC50	6000.0	nM	10.1016/j.ejmech.2020.112327
Homo sapiens	HeLa	IC50	6130.0	nM	10.1016/j.bmc.2015.11.007
Homo sapiens	HeLa	IC50	6510.0	nM	10.1016/j.ejmech.2019.01.004
Homo sapiens	HeLa	IC50	8280.0	nM	10.1021/acs.jmedchem.1c01362
Homo sapiens	HeLa	IC50	8930.0	nM	10.1016/j.bmcl.2011.09.063
Homo sapiens	HeLa	IC50	10100.0	nM	10.1016/j.bmc.2017.03.065
Homo sapiens	HeLa	IC50	11620.0	nM	10.1016/j.ejmech.2015.01.024
Homo sapiens	HeLa	IC50	14000.0	nM	10.1016/j.ejmech.2015.07.007
Homo sapiens	HeLa	IC50	19800.0	nM	10.1016/j.ejmech.2015.11.037
Homo sapiens	HeLa	IC50	50000.0	nM	10.1039/C8MD00278A
Homo sapiens	HeLa	IC50	60010.0	nM	10.1016/j.ejmech.2016.12.035
Homo sapiens	HeLa	IC50	nan	None	10.1021/acs.jnatprod.6b00782
Homo sapiens	HeLa	RatioGI50	5.5	None	10.1021/jm1005447
Homo sapiens	HeLa	Ratio IC50	0.1	None	10.1016/j.ejmech.2015.11.037
Homo sapiens	H-EMC-SS	IC50	95.58	nM	10.6019/CHEMBL1201861
Homo sapiens	Hemoglobin beta chain	Potency	5.0	nM	None
Homo sapiens	Hemoglobin beta chain	Potency	1000.0	nM	None
Homo sapiens	HEp-2	ED50	0.02	ug ml-1	10.1021/np078016r
Homo sapiens	HEp-2	IC50	0.02	ug.mL-1	10.1021/np800126f
Homo sapiens	HEp-2	IC50	700.0	nM	10.1016/j.bmc.2010.10.042
Homo sapiens	HEp-2	IC50	3010.0	nM	10.1016/j.bmcl.2018.10.014
Homo sapiens	HEp-2	IC50	3040.0	nM	10.1016/j.ejmech.2017.09.005
Homo sapiens	HepG2	Activity	nan	None	10.1021/acs.jmedchem.1c01362
Homo sapiens	HepG2	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	HepG2	CC50	20.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	HepG2	CC50	40.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	HepG2	FC	4.0	None	10.1016/j.bmcl.2011.12.095
Homo sapiens	HepG2	GI50	100.0	nM	10.1021/jm900469e
Homo sapiens	HepG2	GI50	220.0	nM	10.1021/jm300605m
Homo sapiens	HepG2	GI50	nan	None	10.1016/j.ejmech.2010.11.013
Homo sapiens	HepG2	IC50	0.09	ug.mL-1	10.1016/S0960-894X(01)80158-X
Homo sapiens	HepG2	IC50	6.3	nM	10.1021/jm990124q
Homo sapiens	HepG2	IC50	10.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	HepG2	IC50	20.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	HepG2	IC50	20.0	nM	10.1021/np2009219
Homo sapiens	HepG2	IC50	30.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	HepG2	IC50	40.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	HepG2	IC50	50.0	nM	10.1016/j.bmcl.2013.12.001
Homo sapiens	HepG2	IC50	60.0	nM	10.1021/np900231e
Homo sapiens	HepG2	IC50	100.0	nM	10.1021/jm3001532
Homo sapiens	HepG2	IC50	110.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	HepG2	IC50	130.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	HepG2	IC50	200.0	nM	10.1021/jm900469e
Homo sapiens	HepG2	IC50	200.0	nM	10.1021/np400433g
Homo sapiens	HepG2	IC50	200.0	nM	10.1039/C4MD00344F
Homo sapiens	HepG2	IC50	300.0	nM	10.1021/np8002723
Homo sapiens	HepG2	IC50	370.0	nM	10.1016/j.ejmech.2018.07.032
Homo sapiens	HepG2	IC50	400.0	nM	10.1016/j.ejmech.2020.112509
Homo sapiens	HepG2	IC50	430.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	HepG2	IC50	455.0	nM	10.1021/jm900365v
Homo sapiens	HepG2	IC50	500.0	nM	10.1016/j.bmc.2018.07.001
Homo sapiens	HepG2	IC50	600.0	nM	10.1021/np400545v
Homo sapiens	HepG2	IC50	660.0	nM	10.1016/j.bmcl.2018.12.059
Homo sapiens	HepG2	IC50	1000.0	nM	10.1016/j.bmc.2016.01.013
Homo sapiens	HepG2	IC50	1360.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	HepG2	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	HepG2	IC50	3500.0	nM	10.1021/acs.jmedchem.1c01362
Homo sapiens	HepG2	IC50	4370.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	HepG2	IC50	4790.0	nM	10.1016/j.ejmech.2019.01.004
Homo sapiens	HepG2	IC50	4920.0	nM	10.1016/j.bmc.2017.04.030
Homo sapiens	HepG2	IC50	5690.0	nM	10.1016/j.ejmech.2019.02.072
Homo sapiens	HepG2	IC50	6080.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	HepG2	IC50	6400.0	nM	10.1016/j.bmcl.2011.12.095
Homo sapiens	HepG2	IC50	13200.0	nM	10.1016/j.ejmech.2018.07.028
Homo sapiens	HepG2	IC50	32300.0	nM	10.1016/j.bmcl.2013.03.044
Homo sapiens	HepG2	IC50 relative	200.0	nM	10.6019/EOS300108
Homo sapiens	HepG2	LC50	nan	None	10.1016/j.ejmech.2010.11.013
Homo sapiens	HepG2	Potency	251.2	nM	None
Homo sapiens	HepG2	TGI	nan	None	10.1016/j.ejmech.2010.11.013
Homo sapiens	HERG	IC50	nan	None	None
Homo sapiens	HERG	Ki	nan	None	None
Homo sapiens	Heterogeneous nuclear ribonucleoprotein A1	Bmax	67.0	pg/mm2	10.1016/j.bmc.2011.09.059
Homo sapiens	Heterogeneous nuclear ribonucleoprotein A1	Inhibition	nan	%	10.1016/j.bmc.2011.09.059
Homo sapiens	Heterogeneous nuclear ribonucleoprotein A1	Kd	82.7	nM	10.1016/j.bmc.2011.09.059
Homo sapiens	HGC-27	IC50	4.073	nM	10.6019/CHEMBL1201861
Homo sapiens	HGC-27	IC50	166.0	nM	10.1021/acs.jmedchem.2c00635
Homo sapiens	HGC-27	IC50	150000.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	HH	IC50	13.52	nM	10.6019/CHEMBL1201861
Homo sapiens	Histamine H1 receptor	IC50	nan	None	None
Homo sapiens	Histamine H1 receptor	Ki	nan	None	None
Homo sapiens	Histamine H2 receptor	IC50	nan	None	None
Homo sapiens	Histamine H2 receptor	Ki	nan	None	None
Homo sapiens	Histone acetyltransferase GCN5	Potency	17782.8	nM	None
Homo sapiens	Histone deacetylase	IC50	50.0	nM	10.1016/j.ejmech.2020.112844
Homo sapiens	Histone deacetylase 6	Inhibition	-24.82	%	10.6019/CHEMBL4808148
Homo sapiens	Histone deacetylase 6	Inhibition	-1.11	%	10.6019/CHEMBL4808148
Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Potency	8912.5	nM	None
Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Potency	44668.4	nM	None
Homo sapiens	HL-60	Activity	4.0	%	10.1016/j.ejmech.2011.01.061
Homo sapiens	HL-60	Activity	6.0	%	10.1016/j.ejmech.2013.01.027
Homo sapiens	HL-60	Activity	7.0	%	10.1016/j.bmcl.2011.10.112
Homo sapiens	HL-60	Activity	11.0	%	10.1016/j.bmc.2011.09.060
Homo sapiens	HL-60	Activity	17.0	%	10.1016/j.bmc.2011.09.060
Homo sapiens	HL-60	Activity	18.0	%	10.1016/j.bmcl.2011.10.112
Homo sapiens	HL-60	Activity	35.0	%	10.1016/j.ejmech.2011.01.061
Homo sapiens	HL-60	Activity	46.1	%	10.1039/C3MD00055A
Homo sapiens	HL-60	Activity	51.0	%	10.1016/j.ejmech.2013.01.027
Homo sapiens	HL-60	Activity	52.0	%	10.1016/j.bmc.2011.09.060
Homo sapiens	HL-60	Activity	53.3	%	10.1039/C3MD00055A
Homo sapiens	HL-60	Activity	55.5	%	10.1016/j.ejmech.2011.12.018
Homo sapiens	HL-60	Activity	61.8	%	10.1039/C3MD00055A
Homo sapiens	HL-60	Activity	69.0	%	10.1016/j.ejmech.2013.01.027
Homo sapiens	HL-60	Activity	88.0	%	10.1016/j.ejmech.2013.01.027
Homo sapiens	HL-60	Activity	96.0	%	10.1016/j.ejmech.2011.01.061
Homo sapiens	HL-60	Activity	nan	None	10.1016/j.bmc.2020.115443
Homo sapiens	HL-60	Activity	nan	None	10.1016/j.bmcl.2007.10.011
Homo sapiens	HL-60	Activity	nan	None	10.1016/j.ejmech.2011.01.061
Homo sapiens	HL-60	Activity	nan	None	10.1016/j.ejmech.2013.03.028
Homo sapiens	HL-60	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	HL-60	FC	0.0	None	10.1016/j.bmc.2020.115443
Homo sapiens	HL-60	GI50	1.7	nM	10.1016/j.bmc.2007.10.012
Homo sapiens	HL-60	GI50	3.0	nM	10.1021/jm300605m
Homo sapiens	HL-60	GI50	14.96	nM	None
Homo sapiens	HL-60	GI50	30.0	nM	10.1016/j.bmc.2007.03.067
Homo sapiens	HL-60	IC50	3.734	nM	10.6019/CHEMBL1201861
Homo sapiens	HL-60	IC50	5.0	nM	10.1016/S0960-894X(97)10181-0
Homo sapiens	HL-60	IC50	6.0	nM	10.1021/jm900365v
Homo sapiens	HL-60	IC50	6.7	nM	10.1016/j.bmcl.2018.01.054
Homo sapiens	HL-60	IC50	13.0	nM	10.1016/j.bmcl.2007.12.053
Homo sapiens	HL-60	IC50	15.0	nM	10.1016/j.ejmech.2015.07.007
Homo sapiens	HL-60	IC50	17.0	nM	10.1016/j.bmc.2010.09.069
Homo sapiens	HL-60	IC50	18.0	nM	10.1016/j.bmc.2010.10.057
Homo sapiens	HL-60	IC50	18.0	nM	10.1016/j.bmc.2011.01.064
Homo sapiens	HL-60	IC50	18.0	nM	10.1016/j.bmc.2020.115443
Homo sapiens	HL-60	IC50	18.0	nM	10.1016/j.bmcl.2007.04.064
Homo sapiens	HL-60	IC50	19.0	nM	10.1016/j.ejmech.2016.05.065
Homo sapiens	HL-60	IC50	19.0	nM	10.1016/j.ejmech.2017.04.071
Homo sapiens	HL-60	IC50	20.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	HL-60	IC50	60.0	nM	10.1021/np400433g
Homo sapiens	HL-60	IC50	64.0	nM	10.1016/j.bmcl.2018.11.049
Homo sapiens	HL-60	IC50	65.0	nM	10.1016/j.bmc.2009.12.069
Homo sapiens	HL-60	IC50	65.0	nM	10.1016/j.ejmech.2011.01.011
Homo sapiens	HL-60	IC50	66.0	nM	10.1016/s0960-894x(02)01041-7
Homo sapiens	HL-60	IC50	67.0	nM	10.1016/j.bmcl.2009.09.091
Homo sapiens	HL-60	IC50	70.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	HL-60	IC50	89.0	nM	10.1016/j.bmcl.2009.03.058
Homo sapiens	HL-60	IC50	100.0	nM	10.1016/j.bmc.2010.03.051
Homo sapiens	HL-60	IC50	100.0	nM	10.1016/j.ejmech.2011.04.029
Homo sapiens	HL-60	IC50	420.0	nM	10.1039/C8MD00278A
Homo sapiens	HL-60	IC50	590.0	nM	10.1016/j.bmcl.2010.03.048
Homo sapiens	HL-60	IC50	600.0	nM	10.1016/j.ejmech.2012.01.014
Homo sapiens	HL-60	IC50	800.0	nM	10.1021/np900028v
Homo sapiens	HL-60	IC50	910.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	HL-60	IC50	920.0	nM	10.1021/acs.jnatprod.7b00387
Homo sapiens	HL-60	IC50	1700.0	nM	10.1016/j.bmcl.2020.127673
Homo sapiens	HL-60	IC50	130000.0	nM	10.1021/np058007n
Homo sapiens	HL-60	RatioGI50	0.9	None	10.1016/j.bmc.2007.10.012
Homo sapiens	HLE	IC50	5.753	nM	10.6019/CHEMBL1201861
Homo sapiens	HMG-CoA reductase	IC50	nan	None	None
Homo sapiens	HMG-CoA reductase	Ki	nan	None	None
Homo sapiens	HMV-2 cell line	IC50	8.887	nM	10.6019/CHEMBL1201861
Homo sapiens	HN	IC50	1.399	nM	10.6019/CHEMBL1201861
Homo sapiens	HO-1-N-1	IC50	0.8385	nM	10.6019/CHEMBL1201861
Homo sapiens	HOC-21 cell line	IC50	0.0147	ug.mL-1	10.1021/jm00045a007
Homo sapiens	HOC-21 cell line	IC50	0.0147	ug.mL-1	10.1021/jm970765q
Homo sapiens	Homo sapiens	Activity	0.2	%	10.1021/jm00069a020
Homo sapiens	Homo sapiens	Activity	0.5	%	10.1021/jm00069a020
Homo sapiens	Homo sapiens	Activity	1.8	None	10.1021/jm00069a020
Homo sapiens	Homo sapiens	Activity	2.3	None	10.1021/jm00069a020
Homo sapiens	Homo sapiens	Activity	13.0	%	10.1021/jm00069a020
Homo sapiens	Homo sapiens	K	30.0	1/Maa	10.1021/jm00069a020
Homo sapiens	Homo sapiens	K	4700.0	1/Maa	10.1021/jm00069a020
Homo sapiens	Homo sapiens	Lactone	5.3	%	10.1021/jm000144o
Homo sapiens	Homo sapiens	Lactone	7.0	%	10.1021/jm9902279
Homo sapiens	Homo sapiens	T1/2	0.1767	hr	10.1021/jm00069a020
Homo sapiens	Homo sapiens	T1/2	0.21	hr	10.1021/jm00069a020
Homo sapiens	Homo sapiens	T1/2	0.2808	hr	10.1021/jm00069a020
Homo sapiens	Homo sapiens	T1/2	0.36	hr	10.1021/jm000144o
Homo sapiens	Homo sapiens	T bound	1.3	ns	10.1021/jm00027a005
Homo sapiens	Homo sapiens	T bound	2.7	ns	10.1021/jm00027a005
Homo sapiens	HOP-18	GI50	122.18	nM	None
Homo sapiens	HOP-62	GI50	10.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	HOP-62	GI50	10.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	HOP-62	GI50	10.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm000029d
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm040025z
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm060046o
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm0613119
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm070307+
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm070361q
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm101338z
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm200719v
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm201512x
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm401471v
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm500294a
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm800259e
Homo sapiens	HOP-62	GI50	10.0	nM	10.1021/jm901649x
Homo sapiens	HOP-62	GI50	11.56	nM	None
Homo sapiens	HOP-62	IC50	3293.6	nM	10.6019/CHEMBL1201861
Homo sapiens	HOP-92	GI50	33.73	nM	None
Homo sapiens	HOP-92	IC50	8.787	nM	10.6019/CHEMBL1201861
Homo sapiens	HOS	IC50	1.398	nM	10.6019/CHEMBL1201861
Homo sapiens	HPAF-II	IC50	55.12	nM	10.6019/CHEMBL1201861
Homo sapiens	Hs-578T	GI50	816.58	nM	None
Homo sapiens	Hs-578T	IC50	144.69	nM	10.6019/CHEMBL1201861
Homo sapiens	HSC-2	IC50	11.7	nM	10.6019/CHEMBL1201861
Homo sapiens	HSC-3	IC50	3.015	nM	10.6019/CHEMBL1201861
Homo sapiens	HSC-4	IC50	0.1816	nM	10.6019/CHEMBL1201861
Homo sapiens	HT	IC50	29.71	nM	10.6019/CHEMBL1201861
Homo sapiens	HT-1080	IC50	0.3944	nM	10.6019/CHEMBL1201861
Homo sapiens	HT-1080	IC50	80.0	nM	10.1016/j.bmc.2010.10.057
Homo sapiens	HT-1080	IC50	80.0	nM	10.1016/j.bmc.2011.01.064
Homo sapiens	HT-1080	IC50	80.0	nM	10.1016/j.bmcl.2007.04.064
Homo sapiens	HT-1080	Inhibition	-11.7	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	-7.1	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	-3.8	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	-3.2	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	-0.4	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	5.4	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	49.5	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	62.0	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	65.8	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	77.0	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	93.1	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT-1080	Inhibition	93.8	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	HT1197	IC50	1093.19	nM	10.6019/CHEMBL1201861
Homo sapiens	HT-1376	IC50	1780.55	nM	10.6019/CHEMBL1201861
Homo sapiens	HT-144	IC50	17.86	nM	10.6019/CHEMBL1201861
Homo sapiens	HT-29	Activity	11.4	%	10.1016/j.bmc.2016.04.036
Homo sapiens	HT-29	Activity	12.79	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	Activity	19.64	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	Activity	27.27	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	Activity	44.0	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	Activity	44.8	%	10.1021/jm900469e
Homo sapiens	HT-29	Activity	47.95	%	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	Activity	48.33	%	10.1016/j.bmc.2013.03.052
Homo sapiens	HT-29	Activity	nan	None	10.1016/j.bmc.2007.04.044
Homo sapiens	HT-29	Activity	nan	None	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	Activity	nan	None	10.1016/j.ejmech.2015.11.044
Homo sapiens	HT-29	Activity	nan	None	10.1021/jm900469e
Homo sapiens	HT-29	Activity_index	0.33	None	10.1016/j.ejmech.2015.11.044
Homo sapiens	HT-29	Activity_index	1.11	None	10.1016/j.ejmech.2015.11.044
Homo sapiens	HT-29	Activity_index	1.55	None	10.1016/j.ejmech.2015.11.044
Homo sapiens	HT-29	EC50	60.0	nM	10.1021/np100352e
Homo sapiens	HT-29	ED50	0.06	uM	10.1021/np100503q
Homo sapiens	HT-29	ED50	0.06	uM	10.1021/np900517h
Homo sapiens	HT-29	GI	52.0	%	10.1016/j.bmc.2013.03.052
Homo sapiens	HT-29	GI50	30.0	nM	10.1021/jm900469e
Homo sapiens	HT-29	GI50	44.87	nM	None
Homo sapiens	HT-29	GI50	50.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	HT-29	GI50	50.0	nM	10.1016/j.ejmech.2013.06.001
Homo sapiens	HT-29	IC50	0.7	nM	10.1021/np4007074
Homo sapiens	HT-29	IC50	14.0	nM	10.1016/j.bmc.2006.12.010
Homo sapiens	HT-29	IC50	30.0	nM	10.1016/j.ejmech.2019.111700
Homo sapiens	HT-29	IC50	30.0	nM	10.1021/jm051247f
Homo sapiens	HT-29	IC50	46.0	nM	10.1021/jm00003a001
Homo sapiens	HT-29	IC50	60.0	nM	10.1016/j.bmcl.2013.12.001
Homo sapiens	HT-29	IC50	70.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	HT-29	IC50	80.0	nM	10.1021/jm000129j
Homo sapiens	HT-29	IC50	85.52	nM	10.6019/CHEMBL1201861
Homo sapiens	HT-29	IC50	87.8	nM	10.1021/jm9605804
Homo sapiens	HT-29	IC50	90.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	HT-29	IC50	120.0	nM	10.1016/j.bmcl.2009.06.010
Homo sapiens	HT-29	IC50	260.0	nM	10.1021/jm101354u
Homo sapiens	HT-29	IC50	400.0	nM	10.1021/jm900469e
Homo sapiens	HT-29	IC50	850.0	nM	10.1016/j.bmc.2009.12.069
Homo sapiens	HT-29	IC50	1070.0	nM	10.1016/j.bmcl.2009.09.091
Homo sapiens	HT-29	IC50	1220.0	nM	10.1021/np900077h
Homo sapiens	HT-29	IC50	1370.0	nM	10.1021/acs.jmedchem.2c00635
Homo sapiens	HT-29	IC50	1400.0	nM	10.1016/s0960-894x(02)01041-7
Homo sapiens	HT-29	IC50	2000.0	nM	10.1021/np8002723
Homo sapiens	HT-29	IC50	3160.0	nM	10.1016/j.bmcl.2008.03.074
Homo sapiens	HT-29	IC50	3160.0	nM	10.1021/jm8001982
Homo sapiens	HT-29	IC50	8810.0	nM	10.1016/j.bmcl.2008.03.074
Homo sapiens	HT-29	IC50	8810.0	nM	10.1021/jm8001982
Homo sapiens	HT-29	IC50	10000.0	nM	10.1016/j.ejmech.2011.07.036
Homo sapiens	HT-29	IC50	100000.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	HT-29	IC50	150000.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	HT-29	IC50	nan	None	10.1016/j.bmc.2012.06.030
Homo sapiens	HT-29	IC50	nan	None	10.1021/acs.jnatprod.6b01069
Homo sapiens	HT-29	IC50	nan	None	10.1021/np200062x
Homo sapiens	HT-29	LC50	31620.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	HT-29	LC50	31620.0	nM	10.1016/j.ejmech.2013.06.001
Homo sapiens	HT-29	Ratio IC50	2.8	None	10.1016/j.bmcl.2008.03.074
Homo sapiens	HT-29	TGI	790.0	nM	10.1016/j.ejmech.2013.06.001
Homo sapiens	HT-29	TGI	31620.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	HT-29	Tumor growth delay	4.0	day	10.1021/jm980400l
Homo sapiens	HT-29	Tumor growth delay	nan	None	10.1021/jm980400l
Homo sapiens	HT-3	IC50	0.2119	nM	10.6019/CHEMBL1201861
Homo sapiens	HT55	IC50	192.44	nM	10.6019/CHEMBL1201861
Homo sapiens	HTC-C3	IC50	31.47	nM	10.6019/CHEMBL1201861
Homo sapiens	HuCCT-1	IC50	73.21	nM	10.6019/CHEMBL1201861
Homo sapiens	Huh-7	Activity	nan	None	10.1016/j.ejmech.2019.01.056
Homo sapiens	Huh-7	GI50	6.0	nM	10.1016/j.ejmech.2018.04.040
Homo sapiens	Huh-7	GI50	99.0	nM	10.1021/acs.jmedchem.8b00639
Homo sapiens	Huh-7	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
Homo sapiens	Huh-7	IC50	2.3	nM	10.1021/acs.jnatprod.8b00430
Homo sapiens	Huh-7	IC50	60.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	Huh-7	IC50	100.0	nM	10.1021/jm3001532
Homo sapiens	Huh-7	IC50	115.84	nM	10.6019/CHEMBL1201861
Homo sapiens	Huh-7	IC50	150.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	Huh-7	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	Huntingtin	Potency	5623.4	nM	None
Homo sapiens	HuO-3N1	IC50	12.65	nM	10.6019/CHEMBL1201861
Homo sapiens	HuO9	IC50	2.881	nM	10.6019/CHEMBL1201861
Homo sapiens	HuP-T3	IC50	36.35	nM	10.6019/CHEMBL1201861
Homo sapiens	HuP-T4	IC50	0.8814	nM	10.6019/CHEMBL1201861
Homo sapiens	HuTu80	IC50	3.382	nM	10.6019/CHEMBL1201861
Homo sapiens	HUVEC	ED50	258.0	nM	10.1021/np0304417
Homo sapiens	HUVEC	IC50	10.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	HUVEC	IC50	12.0	nM	10.1016/j.bmc.2022.116793
Homo sapiens	HUVEC	IC50	60.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	HUVEC	IC50	200.0	nM	10.1016/j.ejmech.2015.01.007
Homo sapiens	HUVEC	Inhibition	nan	%	10.1016/j.bmc.2010.09.069
Homo sapiens	Hypoxia-inducible factor 1 alpha	Inhibition	62.3	%	10.1016/j.bmc.2021.116375
Homo sapiens	Hypoxia-inducible factor 1 alpha	Potency	79.4	nM	None
Homo sapiens	Hypoxia-inducible factor 1 alpha	Potency	125.9	nM	None
Homo sapiens	IA-LM	IC50	12.0	nM	10.6019/CHEMBL1201861
Homo sapiens	IGR-1	IC50	151.26	nM	10.6019/CHEMBL1201861
Homo sapiens	IGROV-1	GI50	184.08	nM	None
Homo sapiens	IGROV-1	IC50	12.0	nM	10.1021/jm8001982
Homo sapiens	IGROV-1	IC50	36.34	nM	10.6019/CHEMBL1201861
Homo sapiens	IGROV-1	IC50	1650.0	nM	10.1021/jm8001982
Homo sapiens	IGROV-1	ID50	3.2	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	IMR-32	IC50	80.0	nM	10.1016/j.bmc.2010.10.042
Homo sapiens	IMR-90	IC50	430.0	nM	10.1016/j.bmc.2012.06.030
Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1	Inhibition	nan	%	10.1016/j.bmc.2012.02.022
Homo sapiens	Interleukin-8 receptor A	IC50	nan	None	None
Homo sapiens	Interleukin-8 receptor A	Ki	nan	None	None
Homo sapiens	Interleukin-8 receptor B	IC50	nan	None	None
Homo sapiens	Interleukin-8 receptor B	Ki	nan	None	None
Homo sapiens	IST-MEL1	IC50	3.81	nM	10.6019/CHEMBL1201861
Homo sapiens	IST-MES1	IC50	10.56	nM	10.6019/CHEMBL1201861
Homo sapiens	IST-SL1	IC50	34.38	nM	10.6019/CHEMBL1201861
Homo sapiens	J82	IC50	4.722	nM	10.6019/CHEMBL1201861
Homo sapiens	JAR	IC50	14.54	nM	10.6019/CHEMBL1201861
Homo sapiens	JEG-3	IC50	13.12	nM	10.6019/CHEMBL1201861
Homo sapiens	J-RT3-T3-5	IC50	2.579	nM	10.6019/CHEMBL1201861
Homo sapiens	Jurkat	Activity	0.0	%	10.1021/acs.jnatprod.0c00261
Homo sapiens	Jurkat	Activity	0.12	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	0.132	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	1.92	%	10.1021/acs.jnatprod.0c00261
Homo sapiens	Jurkat	Activity	3.53	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	8.9	%	10.1016/j.bmc.2016.04.036
Homo sapiens	Jurkat	Activity	26.08	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	29.83	%	10.1021/acs.jnatprod.0c00261
Homo sapiens	Jurkat	Activity	32.64	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	36.41	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	37.37	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	63.71	%	10.1016/j.ejmech.2017.09.009
Homo sapiens	Jurkat	Activity	68.24	%	10.1021/acs.jnatprod.0c00261
Homo sapiens	Jurkat	Activity	nan	None	10.1016/j.ejmech.2011.12.003
Homo sapiens	Jurkat	GI50	60.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	Jurkat	GI50	90.0	nM	10.1021/jm1009428
Homo sapiens	Jurkat	IC50	1.4	nM	10.1016/j.bmcl.2007.11.029
Homo sapiens	Jurkat	IC50	5.6	nM	10.1021/jm010041l
Homo sapiens	Jurkat	IC50	5.6	nM	10.1021/jm020420u
Homo sapiens	Jurkat	IC50	26.0	nM	10.1016/j.ejmech.2012.01.014
Homo sapiens	Jurkat	IC50	85.0	nM	10.1016/j.ejmech.2015.12.050
Homo sapiens	Jurkat	IC50	100.0	nM	10.1016/j.ejmech.2021.113639
Homo sapiens	Jurkat	IC50	110.0	nM	10.1016/j.ejmech.2014.06.050
Homo sapiens	Jurkat	IC50	22000.0	nM	10.1016/j.bmc.2019.03.011
Homo sapiens	Jurkat	IC50	22000.0	nM	10.1016/j.ejmech.2020.113102
Homo sapiens	Jurkat	IC50	51500.0	nM	10.1016/j.bmc.2019.03.011
Homo sapiens	Jurkat	IC50 ratio	1.4	None	10.1021/jm010041l
Homo sapiens	Jurkat	IC50 ratio	2.0	None	10.1021/jm010041l
Homo sapiens	JVM-2	IC50	3029.5	nM	10.6019/CHEMBL1201861
Homo sapiens	JVM-3	IC50	2.504	nM	10.6019/CHEMBL1201861
Homo sapiens	K5	IC50	3.201	nM	10.6019/CHEMBL1201861
Homo sapiens	K562	Activity	39.6	%	10.1016/j.bmc.2016.04.036
Homo sapiens	K562	Activity	nan	None	10.1016/j.bmcl.2016.03.021
Homo sapiens	K562	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	K562	GI50	60.0	nM	10.1016/j.bmc.2010.05.062
Homo sapiens	K562	GI50	60.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	K562	GI50	76.38	nM	None
Homo sapiens	K562	IC50	2.0	nM	10.1021/np100201p
Homo sapiens	K562	IC50	2.0	nM	10.1021/np900827a
Homo sapiens	K562	IC50	3.0	nM	10.1021/acs.jmedchem.5b00910
Homo sapiens	K562	IC50	3.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	K562	IC50	31.0	nM	10.1021/ml400125z
Homo sapiens	K562	IC50	40.0	nM	10.1016/j.bmcl.2013.12.001
Homo sapiens	K562	IC50	40.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	K562	IC50	40.0	nM	10.1021/np060609z
Homo sapiens	K562	IC50	40.0	nM	10.1021/np070332i
Homo sapiens	K562	IC50	57.0	nM	10.1021/jm980400l
Homo sapiens	K562	IC50	70.0	nM	10.1016/j.ejmech.2018.07.032
Homo sapiens	K562	IC50	80.0	nM	10.1016/j.bmc.2009.10.049
Homo sapiens	K562	IC50	80.0	nM	10.1016/j.bmc.2010.01.065
Homo sapiens	K562	IC50	90.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	K562	IC50	130.0	nM	10.1016/j.ejmech.2015.01.007
Homo sapiens	K562	IC50	320.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	K562	IC50	400.0	nM	10.1021/np400545v
Homo sapiens	K562	IC50	580.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	K562	IC50	590.0	nM	10.1016/j.bmcl.2010.11.037
Homo sapiens	K562	IC50	711.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	K562	IC50	1077.74	nM	10.6019/CHEMBL1201861
Homo sapiens	K562	IC50	1180.0	nM	10.1016/j.ejmech.2012.01.015
Homo sapiens	K562	IC50	1400.0	nM	10.1021/jm900469e
Homo sapiens	K562	IC50	2690.0	nM	10.1016/j.ejmech.2020.112327
Homo sapiens	K562	IC50	5370.0	nM	10.1016/j.ejmech.2015.01.024
Homo sapiens	K562	IC50	nan	None	10.1016/j.bmc.2017.04.030
Homo sapiens	K562	LC50	100000.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	K562	RatioGI50	16.5	None	10.1016/j.bmc.2010.05.062
Homo sapiens	K562	TGI	50120.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	KALS-1	IC50	69.89	nM	10.6019/CHEMBL1201861
Homo sapiens	Kappa opioid receptor	IC50	nan	None	None
Homo sapiens	Kappa opioid receptor	Ki	nan	None	None
Homo sapiens	KARPAS-299	IC50	2892.53	nM	10.6019/CHEMBL1201861
Homo sapiens	KARPAS-45	IC50	134.47	nM	10.6019/CHEMBL1201861
Homo sapiens	Kasumi 1	IC50	4.066	nM	10.6019/CHEMBL1201861
Homo sapiens	KATO III stomach cancer cell line	IC50	1170.0	nM	10.1016/0960-894X(96)00131-X
Homo sapiens	KATO III stomach cancer cell line	IC50	1170.0	nM	10.1016/0960-894X(96)00132-1
Homo sapiens	KATO III stomach cancer cell line	IC50	46000000.0	nM	10.1016/s0960-894x(99)00555-7
Homo sapiens	KB	CC50	6.0	nM	10.1021/jm9707232
Homo sapiens	KB	EC50	0.01	ug.mL-1	10.1021/np010459m
Homo sapiens	KB	EC50	0.01	ug.mL-1	10.1021/np040027m
Homo sapiens	KB	EC50	3.6	nM	10.1021/np070005a
Homo sapiens	KB	ED50	2.3	ug ml-1	10.1021/np50022a010
Homo sapiens	KB	ED50	20.9	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	KB	ED50	22.0	nM	10.1021/np0304417
Homo sapiens	KB	IC50	0.005	ug.mL-1	10.1016/j.bmcl.2004.05.032
Homo sapiens	KB	IC50	0.01	ug.mL-1	10.1016/S0960-894X(01)80158-X
Homo sapiens	KB	IC50	0.01	ug.mL-1	10.1021/np960336f
Homo sapiens	KB	IC50	0.04	ug.mL-1	10.1016/S0960-894X(01)80158-X
Homo sapiens	KB	IC50	3.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	KB	IC50	8.0	nM	10.1021/jm9605804
Homo sapiens	KB	IC50	8.8	nM	10.1016/j.bmc.2012.05.030
Homo sapiens	KB	IC50	9.0	nM	10.1016/j.bmcl.2003.08.012
Homo sapiens	KB	IC50	13.0	nM	10.1016/j.ejmech.2010.03.013
Homo sapiens	KB	IC50	20.0	nM	10.1016/j.bmcl.2004.08.070
Homo sapiens	KB	IC50	20.0	nM	10.1021/np4007074
Homo sapiens	KB	IC50	28.7	nM	10.1021/np010420h
Homo sapiens	KB	IC50	30.0	nM	10.1021/jm9806087
Homo sapiens	KB	IC50	35.0	nM	10.1021/jm9806087
Homo sapiens	KB	IC50	37.0	nM	10.1016/j.ejmech.2016.02.070
Homo sapiens	KB	IC50	37.0	nM	10.1021/jm5003588
Homo sapiens	KB	IC50	38.0	nM	10.1021/jm900365v
Homo sapiens	KB	IC50	40.0	nM	10.1021/jm9806087
Homo sapiens	KB	IC50	50.0	nM	10.1016/j.bmcl.2017.02.066
Homo sapiens	KB	IC50	50.0	nM	10.1016/j.bmcl.2017.09.012
Homo sapiens	KB	IC50	70.0	nM	10.1021/jm9806087
Homo sapiens	KB	IC50	121.0	nM	10.1016/j.bmcl.2012.10.002
Homo sapiens	KB	IC50	1040.0	nM	10.1021/jm9806087
Homo sapiens	KB	IC50	1220.0	nM	10.1021/np900077h
Homo sapiens	KB	Inhibition	100.0	%	10.1016/0960-894X(94)00462-O
Homo sapiens	KB	TD50	0.008	ug ml-1	10.1016/0960-894X(95)00538-5
Homo sapiens	KB	TD50	0.01	ug ml-1	10.1021/jm950465d
Homo sapiens	KB 3-1	IC50	10.0	nM	10.1016/j.bmcl.2004.08.070
Homo sapiens	KB 3-1	IC50	20.0	nM	10.1016/j.bmcl.2004.08.070
Homo sapiens	KE-37	IC50	1.535	nM	10.6019/CHEMBL1201861
Homo sapiens	KG-1	IC50	1.11	nM	10.6019/CHEMBL1201861
Homo sapiens	KG-1	IC50	1600.0	nM	10.1016/j.bmcl.2020.127673
Homo sapiens	KG-1	IC50	2310.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	KGN	IC50	10.59	nM	10.6019/CHEMBL1201861
Homo sapiens	KINGS-1	IC50	332.9	nM	10.6019/CHEMBL1201861
Homo sapiens	KLE	IC50	411.5	nM	10.6019/CHEMBL1201861
Homo sapiens	KM12	GI50	159.22	nM	None
Homo sapiens	KM12	IC50	74.99	nM	10.6019/CHEMBL1201861
Homo sapiens	KM-20L2	GI50	77.62	nM	None
Homo sapiens	KM-H2	IC50	55.67	nM	10.6019/CHEMBL1201861
Homo sapiens	KMOE-2	IC50	11.26	nM	10.6019/CHEMBL1201861
Homo sapiens	KNS-42	IC50	33.14	nM	10.6019/CHEMBL1201861
Homo sapiens	KNS-62	IC50	7.701	nM	10.6019/CHEMBL1201861
Homo sapiens	KNS-81-FD	IC50	19.42	nM	10.6019/CHEMBL1201861
Homo sapiens	KOSC-2	IC50	4.393	nM	10.6019/CHEMBL1201861
Homo sapiens	KP-4	IC50	3.162	nM	10.6019/CHEMBL1201861
Homo sapiens	KP-N-YN	IC50	102.97	nM	10.6019/CHEMBL1201861
Homo sapiens	KP-N-YS	IC50	736.29	nM	10.6019/CHEMBL1201861
Homo sapiens	KS-1	IC50	57.87	nM	10.6019/CHEMBL1201861
Homo sapiens	KU-19-19	IC50	22.03	nM	10.6019/CHEMBL1201861
Homo sapiens	KU812 cell line	IC50	8.365	nM	10.6019/CHEMBL1201861
Homo sapiens	KURAMOCHI	IC50	3634.01	nM	10.6019/CHEMBL1201861
Homo sapiens	KY821	IC50	8.123	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-140	IC50	69.74	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-150 cell line	IC50	245.96	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-180	IC50	13.18	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-270	IC50	5.223	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-410	IC50	78.11	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-450	IC50	23.73	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-510	IC50	6.754	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-520 cell line	IC50	82.56	nM	10.6019/CHEMBL1201861
Homo sapiens	KYSE-70 cell line	IC50	92.14	nM	10.6019/CHEMBL1201861
Homo sapiens	L02	IC50	140.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	L02	IC50	2150.0	nM	10.1016/j.ejmech.2019.02.072
Homo sapiens	L02	IC50	150000.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	L2987	IC50	400.0	nM	10.1016/s0960-894x(01)00707-7
Homo sapiens	L-363	IC50	1.869	nM	10.6019/CHEMBL1201861
Homo sapiens	L-428	IC50	148.3	nM	10.6019/CHEMBL1201861
Homo sapiens	LAMA-84	IC50	7.02	nM	10.6019/CHEMBL1201861
Homo sapiens	LAN-6	IC50	124.47	nM	10.6019/CHEMBL1201861
Homo sapiens	LB1047-RCC	IC50	7.897	nM	10.6019/CHEMBL1201861
Homo sapiens	LB2241-RCC	IC50	2.076	nM	10.6019/CHEMBL1201861
Homo sapiens	LB2518-MEL	IC50	87.25	nM	10.6019/CHEMBL1201861
Homo sapiens	LB373-MEL-D	IC50	91.19	nM	10.6019/CHEMBL1201861
Homo sapiens	LB771-HNC	IC50	196.84	nM	10.6019/CHEMBL1201861
Homo sapiens	LB831-BLC	IC50	18.37	nM	10.6019/CHEMBL1201861
Homo sapiens	LC-2-ad	IC50	2.806	nM	10.6019/CHEMBL1201861
Homo sapiens	LCLC-103H cell line	IC50	20.49	nM	10.6019/CHEMBL1201861
Homo sapiens	LCLC-97TM1	IC50	8.136	nM	10.6019/CHEMBL1201861
Homo sapiens	Leukocyte common antigen	IC50	nan	None	None
Homo sapiens	Leukocyte common antigen	Ki	nan	None	None
Homo sapiens	Leukocyte elastase	IC50	nan	None	None
Homo sapiens	Leukocyte elastase	Ki	nan	None	None
Homo sapiens	LK-2	IC50	35.53	nM	10.6019/CHEMBL1201861
Homo sapiens	LN-229	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
Homo sapiens	LN-405	IC50	517.64	nM	10.6019/CHEMBL1201861
Homo sapiens	LNCaP	Activity	nan	None	10.1021/jm100729b
Homo sapiens	LNCaP	ED50	2.0	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	LNCaP	ED50	10.0	uM	10.1016/j.bmc.2008.10.076
Homo sapiens	LNCaP	ED50	28.0	nM	10.1021/np0304417
Homo sapiens	LNCaP	IC50	86.1	nM	10.1021/np010420h
Homo sapiens	LNCaP C4-2	Inhibition	69.0	%	10.1016/j.bmcl.2006.08.103
Homo sapiens	LNCaP-Clone-FGC	IC50	31.03	nM	10.6019/CHEMBL1201861
Homo sapiens	LoVo	Activity	17.61	%	10.1021/np3003468
Homo sapiens	LoVo	Activity	23.81	%	10.1021/np3003468
Homo sapiens	LoVo	GI50	8.0	nM	10.1021/jm1009428
Homo sapiens	LoVo	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
Homo sapiens	LoVo	IC50	14.93	nM	10.6019/CHEMBL1201861
Homo sapiens	LoVo	IC50	1540.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	LoVo	IC50	3100.0	nM	10.1021/jm100387d
Homo sapiens	LoVo	Ratio	3.4	None	10.1021/np3003468
Homo sapiens	LOX IMVI	GI50	26.06	nM	None
Homo sapiens	LOX IMVI	IC50	3.72	nM	10.6019/CHEMBL1201861
Homo sapiens	LOX IMVI	IC50	48.0	nM	10.1021/jm00003a001
Homo sapiens	LS-1034	IC50	9492.4	nM	10.6019/CHEMBL1201861
Homo sapiens	LS-123	IC50	7325.59	nM	10.6019/CHEMBL1201861
Homo sapiens	LS-411N	IC50	58.08	nM	10.6019/CHEMBL1201861
Homo sapiens	LS-513	IC50	19.37	nM	10.6019/CHEMBL1201861
Homo sapiens	Lu1	ED50	10.0	uM	10.1016/j.bmc.2008.10.076
Homo sapiens	Lu1	ED50	29.0	nM	10.1021/np0304417
Homo sapiens	Lu1	IC50	28.7	nM	10.1021/np010420h
Homo sapiens	LU-134-A	IC50	0.5865	nM	10.6019/CHEMBL1201861
Homo sapiens	LU-135	IC50	28.16	nM	10.6019/CHEMBL1201861
Homo sapiens	LU-139	IC50	16.44	nM	10.6019/CHEMBL1201861
Homo sapiens	Lu-65	IC50	276.33	nM	10.6019/CHEMBL1201861
Homo sapiens	LU-99A	IC50	3.854	nM	10.6019/CHEMBL1201861
Homo sapiens	Lu-99 cell line	IC50	0.001	ug.mL-1	10.1016/S0960-894X(97)00071-1
Homo sapiens	LX-1	IC50	120.0	nM	10.1021/np010459m
Homo sapiens	LXF-289 cell line	IC50	7.054	nM	10.6019/CHEMBL1201861
Homo sapiens	LXFL 529	GI50	372.39	nM	None
Homo sapiens	Lysine-specific demethylase 4D-like	Potency	2511.9	nM	None
Homo sapiens	Lysine-specific demethylase 4D-like	Potency	3548.1	nM	None
Homo sapiens	Lysine-specific demethylase 4D-like	Potency	4466.8	nM	None
Homo sapiens	Lysine-specific demethylase 4D-like	Potency	10000.0	nM	None
Homo sapiens	Lysosomal alpha-glucosidase	Potency	31622.8	nM	None
Homo sapiens	M059J	IC50	4.095	nM	10.6019/CHEMBL1201861
Homo sapiens	M059J	IC50	5500.0	nM	10.1016/j.ejmech.2015.11.037
Homo sapiens	M14	GI50	20.65	nM	None
Homo sapiens	M14	IC50	9.948	nM	10.6019/CHEMBL1201861
Homo sapiens	M19-MEL	GI50	47.97	nM	None
Homo sapiens	M19-MEL	ID50	13.0	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	Mahlavu	Activity	nan	None	10.1016/j.ejmech.2019.01.056
Homo sapiens	Malme-3M	GI50	173.78	nM	None
Homo sapiens	MAP kinase ERK1	IC50	nan	None	None
Homo sapiens	MAP kinase ERK1	Ki	nan	None	None
Homo sapiens	MAP kinase ERK2	Delta TM	0.24	C	None
Homo sapiens	MAP kinase ERK2	IC50	nan	None	None
Homo sapiens	MAP kinase ERK2	Ki	nan	None	None
Homo sapiens	MAP kinase p38 alpha	IC50	nan	None	None
Homo sapiens	MAP kinase p38 alpha	Ki	nan	None	None
Homo sapiens	Matrix metalloproteinase-1	IC50	nan	None	None
Homo sapiens	Matrix metalloproteinase-1	Ki	nan	None	None
Homo sapiens	Matrix metalloproteinase 9	IC50	nan	None	None
Homo sapiens	Matrix metalloproteinase 9	Ki	nan	None	None
Homo sapiens	MC116	IC50	15.86	nM	10.6019/CHEMBL1201861
Homo sapiens	MCF10	IC50	24770.0	nM	10.1016/j.bmc.2021.116168
Homo sapiens	MCF-10A	IC50	2190.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	MCF-10A	IC50	2580.0	nM	10.1021/acs.jmedchem.2c00968
Homo sapiens	MCF-12A	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	MCF7	Activity	3.05	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	3.06	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	5.39	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	6.71	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	10.4	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	10.92	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	11.36	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	11.51	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	13.42	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	15.15	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	15.27	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	16.24	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	16.91	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	17.42	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	17.59	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	18.36	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	18.67	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	20.21	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	20.25	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	21.21	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	21.25	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	23.38	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	25.73	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	33.0	%	10.1016/j.bmc.2010.05.062
Homo sapiens	MCF7	Activity	41.61	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	46.12	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	47.24	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	52.4	%	10.1016/j.ejmech.2015.07.022
Homo sapiens	MCF7	Activity	58.52	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	59.5	%	10.1016/j.ejmech.2011.10.056
Homo sapiens	MCF7	Activity	65.62	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	71.45	%	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	Activity	nan	None	10.1016/j.bmc.2020.115527
Homo sapiens	MCF7	Activity	nan	None	10.1016/j.bmcl.2011.01.013
Homo sapiens	MCF7	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	MCF7	CC50	20.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	MCF7	CC50	80.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	MCF7	EC50	72.0	nM	10.1021/np0496587
Homo sapiens	MCF7	ED50	3.2	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	MCF7	ED50	10.0	uM	10.1016/j.bmc.2008.10.076
Homo sapiens	MCF7	GI50	2.0	nM	10.1016/j.bmc.2012.12.026
Homo sapiens	MCF7	GI50	10.0	nM	10.1016/j.bmc.2007.03.067
Homo sapiens	MCF7	GI50	10.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	MCF7	GI50	10.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	GI50	10.0	nM	10.1016/j.ejmech.2013.06.001
Homo sapiens	MCF7	GI50	10.0	nM	10.1021/acs.jmedchem.6b00003
Homo sapiens	MCF7	GI50	10.0	nM	10.1021/jm101338z
Homo sapiens	MCF7	GI50	10.0	nM	10.1021/jm500294a
Homo sapiens	MCF7	GI50	10.0	nM	10.1021/jm900469e
Homo sapiens	MCF7	GI50	11.35	nM	None
Homo sapiens	MCF7	GI50	12.0	nM	10.1016/j.ejmech.2019.05.074
Homo sapiens	MCF7	GI50	13.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	MCF7	GI50	13.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	MCF7	GI50	13.0	nM	10.1021/jm200719v
Homo sapiens	MCF7	GI50	13.0	nM	10.1021/jm201512x
Homo sapiens	MCF7	GI50	13.0	nM	10.1021/jm401471v
Homo sapiens	MCF7	GI50	60.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	MCF7	GI50	280.0	nM	10.1021/np9006734
Homo sapiens	MCF7	GI50	350.0	nM	10.1021/acs.jmedchem.1c00318
Homo sapiens	MCF7	GI50	570.0	nM	10.1016/j.bmc.2010.05.062
Homo sapiens	MCF7	GI50	3210.0	nM	10.1021/acs.jmedchem.1c00318
Homo sapiens	MCF7	GI50	6000.0	nM	10.1021/jm1009428
Homo sapiens	MCF7	IC50	0.02	ug.mL-1	10.1016/S0960-894X(01)80158-X
Homo sapiens	MCF7	IC50	0.024	ug.mL-1	10.1021/np400996k
Homo sapiens	MCF7	IC50	0.5	nM	10.1016/j.ejmech.2014.07.035
Homo sapiens	MCF7	IC50	0.6	nM	10.1016/j.ejmech.2014.09.056
Homo sapiens	MCF7	IC50	1.6	nM	10.1021/np100886y
Homo sapiens	MCF7	IC50	1.6	nM	10.1021/np200959j
Homo sapiens	MCF7	IC50	1.8	nM	10.1021/acs.jnatprod.6b00782
Homo sapiens	MCF7	IC50	3.0	nM	10.1016/j.ejmech.2014.07.035
Homo sapiens	MCF7	IC50	3.0	nM	10.1021/jm900365v
Homo sapiens	MCF7	IC50	3.1	nM	10.1021/jm980400l
Homo sapiens	MCF7	IC50	3.3	nM	10.1021/np4007074
Homo sapiens	MCF7	IC50	6.427	nM	10.6019/CHEMBL1201861
Homo sapiens	MCF7	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	MCF7	IC50	10.0	nM	10.1021/jm900365v
Homo sapiens	MCF7	IC50	10.0	nM	10.1021/np400483c
Homo sapiens	MCF7	IC50	20.0	nM	10.1016/j.ejmech.2010.03.013
Homo sapiens	MCF7	IC50	21.0	nM	10.1016/j.bmc.2022.116793
Homo sapiens	MCF7	IC50	26.0	nM	10.1021/ml400125z
Homo sapiens	MCF7	IC50	30.0	nM	10.1016/j.bmcl.2017.02.067
Homo sapiens	MCF7	IC50	30.0	nM	10.1016/j.ejmech.2019.111700
Homo sapiens	MCF7	IC50	40.0	nM	10.1016/j.bmcl.2018.10.014
Homo sapiens	MCF7	IC50	40.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	MCF7	IC50	56.0	nM	10.1016/j.bmc.2011.09.020
Homo sapiens	MCF7	IC50	60.0	nM	10.1016/j.bmc.2009.10.049
Homo sapiens	MCF7	IC50	65.1	nM	10.1021/jm500631u
Homo sapiens	MCF7	IC50	70.0	nM	10.1021/np200062x
Homo sapiens	MCF7	IC50	73.0	nM	10.1021/acs.jnatprod.6b01069
Homo sapiens	MCF7	IC50	80.0	nM	10.1016/j.bmc.2012.06.030
Homo sapiens	MCF7	IC50	80.0	nM	10.1016/j.bmc.2014.11.010
Homo sapiens	MCF7	IC50	84.0	nM	10.1021/acsmedchemlett.9b00513
Homo sapiens	MCF7	IC50	87.5	nM	10.1016/j.bmcl.2017.02.066
Homo sapiens	MCF7	IC50	87.5	nM	10.1016/j.bmcl.2017.09.012
Homo sapiens	MCF7	IC50	100.0	nM	10.1016/j.bmc.2016.01.013
Homo sapiens	MCF7	IC50	100.0	nM	10.1021/jm3001532
Homo sapiens	MCF7	IC50	160.0	nM	10.1021/acsmedchemlett.8b00050
Homo sapiens	MCF7	IC50	200.0	nM	10.1016/j.bmcl.2008.05.103
Homo sapiens	MCF7	IC50	320.0	nM	10.1016/j.bmcl.2004.01.097
Homo sapiens	MCF7	IC50	340.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	MCF7	IC50	350.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	MCF7	IC50	420.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	MCF7	IC50	560.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	MCF7	IC50	650.0	nM	10.1016/j.ejmech.2010.11.046
Homo sapiens	MCF7	IC50	680.0	nM	10.1016/j.bmcl.2018.11.049
Homo sapiens	MCF7	IC50	680.0	nM	10.1016/j.bmcl.2018.12.059
Homo sapiens	MCF7	IC50	1000.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	MCF7	IC50	1100.0	nM	10.1021/jm900469e
Homo sapiens	MCF7	IC50	1220.0	nM	10.1021/np900077h
Homo sapiens	MCF7	IC50	1670.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	MCF7	IC50	1800.0	nM	10.1016/j.bmcl.2011.11.116
Homo sapiens	MCF7	IC50	2430.0	nM	10.1016/j.bmcl.2010.11.037
Homo sapiens	MCF7	IC50	2500.0	nM	10.1016/j.ejmech.2020.112551
Homo sapiens	MCF7	IC50	2600.0	nM	10.1016/j.bmcl.2011.11.116
Homo sapiens	MCF7	IC50	2800.0	nM	10.1016/j.ejmech.2020.112327
Homo sapiens	MCF7	IC50	3910.0	nM	10.1016/j.ejmech.2012.01.015
Homo sapiens	MCF7	IC50	6000.0	nM	10.1016/j.ejmech.2015.11.037
Homo sapiens	MCF7	IC50	7420.0	nM	10.1016/j.bmcl.2009.11.041
Homo sapiens	MCF7	IC50	10000.0	nM	10.1021/np8002723
Homo sapiens	MCF7	IC50	11120.0	nM	10.1021/jm200046z
Homo sapiens	MCF7	IC50	13620.0	nM	10.1016/j.ejmech.2017.09.009
Homo sapiens	MCF7	IC50	14200.0	nM	10.1016/j.ejmech.2010.06.017
Homo sapiens	MCF7	IC50	28660.0	nM	10.1016/j.bmc.2017.03.065
Homo sapiens	MCF7	IC50	71300.0	nM	10.1016/j.ejmech.2016.12.035
Homo sapiens	MCF7	IC50	nan	None	10.1016/j.bmc.2015.11.007
Homo sapiens	MCF7	IC50	nan	None	10.1016/j.ejmech.2010.05.048
Homo sapiens	MCF7	ID50	3.2	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	MCF7	Inhibition	0.05	%	10.1016/j.bmc.2010.01.065
Homo sapiens	MCF7	Inhibition	45.31	%	10.1016/j.bmcl.2014.10.048
Homo sapiens	MCF7	Inhibition	nan	%	10.1016/j.bmcl.2014.10.048
Homo sapiens	MCF7	LC50	100000.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	LC50	100000.0	nM	10.1016/j.ejmech.2013.06.001
Homo sapiens	MCF7	RatioGI50	1.74	None	10.1016/j.bmc.2010.05.062
Homo sapiens	MCF7	Ratio IC50	0.5	None	10.1016/j.ejmech.2015.11.037
Homo sapiens	MCF7	TD50	0.01	ug ml-1	10.1016/0960-894X(95)00538-5
Homo sapiens	MCF7	TGI	160.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	MCF7	TGI	160.0	nM	10.1016/j.ejmech.2013.06.001
Homo sapiens	MC-IXC	IC50	0.513	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-157	IC50	7.569	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-157	IC50	20.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	MDA-MB-175-VII	IC50	83.02	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-231	Activity	73.6	%	10.1039/C9MD00305C
Homo sapiens	MDA-MB-231	Activity	nan	None	10.1016/j.bmcl.2011.01.013
Homo sapiens	MDA-MB-231	Activity	nan	None	10.1016/j.ejmech.2014.06.050
Homo sapiens	MDA-MB-231	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	MDA-MB-231	Activity	nan	None	10.1021/np100891y
Homo sapiens	MDA-MB-231	Activity	nan	None	10.1039/C9MD00305C
Homo sapiens	MDA-MB-231	GI	nan	None	10.1016/j.ejmech.2017.06.066
Homo sapiens	MDA-MB-231	GI50	400.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	MDA-MB-231	GI50	937.56	nM	None
Homo sapiens	MDA-MB-231	GI50	1300.0	nM	10.1021/np9006734
Homo sapiens	MDA-MB-231	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
Homo sapiens	MDA-MB-231	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	MDA-MB-231	IC50	28.4	nM	10.1039/C9MD00305C
Homo sapiens	MDA-MB-231	IC50	162.0	nM	10.1021/ml400125z
Homo sapiens	MDA-MB-231	IC50	170.0	nM	10.1016/j.ejmech.2021.113578
Homo sapiens	MDA-MB-231	IC50	229.98	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-231	IC50	241.0	nM	10.1016/j.ejmech.2021.113544
Homo sapiens	MDA-MB-231	IC50	264.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	MDA-MB-231	IC50	291.0	nM	10.1016/j.bmc.2006.12.010
Homo sapiens	MDA-MB-231	IC50	300.0	nM	10.1016/j.bmc.2010.03.051
Homo sapiens	MDA-MB-231	IC50	307.0	nM	10.1016/j.bmcl.2017.02.066
Homo sapiens	MDA-MB-231	IC50	307.0	nM	10.1016/j.bmcl.2017.09.012
Homo sapiens	MDA-MB-231	IC50	330.0	nM	10.1016/j.bmc.2010.10.019
Homo sapiens	MDA-MB-231	IC50	342.0	nM	10.1016/j.ejmech.2014.06.050
Homo sapiens	MDA-MB-231	IC50	420.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	MDA-MB-231	IC50	490.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	MDA-MB-231	IC50	540.0	nM	10.1021/acsmedchemlett.8b00050
Homo sapiens	MDA-MB-231	IC50	680.0	nM	10.1016/j.bmcl.2009.09.091
Homo sapiens	MDA-MB-231	IC50	920.0	nM	10.1016/j.bmc.2009.12.069
Homo sapiens	MDA-MB-231	IC50	970.0	nM	10.1016/j.ejmech.2011.01.011
Homo sapiens	MDA-MB-231	IC50	1060.0	nM	10.1021/acs.jmedchem.2c00968
Homo sapiens	MDA-MB-231	IC50	1100.0	nM	10.1016/j.bmcl.2009.11.041
Homo sapiens	MDA-MB-231	IC50	2110.0	nM	10.1039/C4MD00133H
Homo sapiens	MDA-MB-231	IC50	2700.0	nM	10.1016/j.bmcl.2011.11.116
Homo sapiens	MDA-MB-231	IC50	4160.0	nM	10.1016/j.bmcl.2007.12.053
Homo sapiens	MDA-MB-231	IC50	4200.0	nM	10.1016/j.ejmech.2010.06.017
Homo sapiens	MDA-MB-231	IC50	5770.0	nM	10.1016/j.bmc.2015.11.007
Homo sapiens	MDA-MB-231	IC50	6400.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	MDA-MB-231	IC50	8830.0	nM	10.1016/j.bmc.2016.09.051
Homo sapiens	MDA-MB-231	IC50	16440.0	nM	10.1039/C8MD00278A
Homo sapiens	MDA-MB-231	IC50	23980.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	MDA-MB-231	IC50	100000.0	nM	10.1016/j.bmcl.2023.129239
Homo sapiens	MDA-MB-231	IC50	nan	None	10.1021/acs.jnatprod.6b00782
Homo sapiens	MDA-MB-231	IC50	nan	None	10.1021/np900312u
Homo sapiens	MDA-MB-231	INH	0.3	uM	10.1016/j.ejmech.2011.04.029
Homo sapiens	MDA-MB-361	IC50	34.43	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-361	IC50	170.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	MDA-MB-415	IC50	134.42	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-435	GI50	33.0	nM	10.1021/jm300605m
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm000029d
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm040025z
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm060046o
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm070307+
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm070361q
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm800259e
Homo sapiens	MDA-MB-435	GI50	40.0	nM	10.1021/jm901649x
Homo sapiens	MDA-MB-435	GI50	65.77	nM	None
Homo sapiens	MDA-MB-435	IC50	1.0	nM	10.1021/jm400906z
Homo sapiens	MDA-MB-435	IC50	15.0	nM	10.1021/jm000144o
Homo sapiens	MDA-MB-435	IC50	43.6	nM	10.1016/j.ejmech.2012.07.050
Homo sapiens	MDA-MB-435	IC50	310.0	nM	10.1021/acs.jmedchem.1c01411
Homo sapiens	MDA-MB-435	IC50	375.0	nM	10.1021/jm000144o
Homo sapiens	MDA-MB-435	IC50	710.0	nM	10.1021/jm100387d
Homo sapiens	MDA-MB-435	IC50	1000.0	nM	10.1021/acs.jmedchem.5b00910
Homo sapiens	MDA-MB-435	IC50	2700.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	MDA-MB-435	IC50	nan	None	10.1021/np200062x
Homo sapiens	MDA-MB-436	IC50	31860.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	MDA-MB-453	IC50	6.965	nM	10.6019/CHEMBL1201861
Homo sapiens	MDA-MB-453	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	MDA-MB-468	IC50	1710.0	nM	10.1016/j.bmc.2016.09.051
Homo sapiens	MDA-MB-468	IC50	14760.0	nM	10.1016/j.bmc.2015.11.007
Homo sapiens	MDA-N	GI50	145.21	nM	None
Homo sapiens	ME-180	IC50	2.692	nM	10.6019/CHEMBL1201861
Homo sapiens	MEG-01	IC50	39.51	nM	10.6019/CHEMBL1201861
Homo sapiens	Melanocortin receptor 3	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 3	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 4	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 4	Ki	nan	None	None
Homo sapiens	Melanocortin receptor 5	IC50	nan	None	None
Homo sapiens	Melanocortin receptor 5	Ki	nan	None	None
Homo sapiens	MEL-HO	IC50	7.628	nM	10.6019/CHEMBL1201861
Homo sapiens	MEL-JUSO	IC50	35.62	nM	10.6019/CHEMBL1201861
Homo sapiens	MeWo	IC50	46.97	nM	10.6019/CHEMBL1201861
Homo sapiens	MFE-280	IC50	21.56	nM	10.6019/CHEMBL1201861
Homo sapiens	MFE-296	IC50	1000.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	MFH-ino	IC50	27.08	nM	10.6019/CHEMBL1201861
Homo sapiens	MFM-223	IC50	5270.72	nM	10.6019/CHEMBL1201861
Homo sapiens	MG-63	IC50	7.654	nM	10.6019/CHEMBL1201861
Homo sapiens	MGC-803	IC50	2960.0	nM	10.1016/j.ejmech.2019.01.004
Homo sapiens	MGC-803	IC50	4270.0	nM	10.1016/j.ejmech.2019.02.072
Homo sapiens	MGC-803	IC50	9450.0	nM	10.1016/j.bmc.2017.03.065
Homo sapiens	MGC-803	IC50	150000.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	MGC-803	TGI	51.5	%	10.1016/j.ejmech.2019.01.004
Homo sapiens	MGC-803	TGI	62.3	%	10.1016/j.ejmech.2019.02.072
Homo sapiens	MHCC97H	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
Homo sapiens	MHH-ES-1	IC50	0.1293	nM	10.6019/CHEMBL1201861
Homo sapiens	MHH-NB-11	IC50	0.8418	nM	10.6019/CHEMBL1201861
Homo sapiens	MHH-PREB-1	IC50	2.733	nM	10.6019/CHEMBL1201861
Homo sapiens	MIA PaCa-2	Activity	3.3	%	10.1021/acs.jmedchem.7b01765
Homo sapiens	MIA PaCa-2	Activity	26.0	%	10.1021/acs.jmedchem.7b01765
Homo sapiens	MIA PaCa-2	Activity	31.0	%	10.1021/acs.jmedchem.7b01765
Homo sapiens	MIA PaCa-2	Activity	42.0	%	10.1021/acs.jmedchem.7b01765
Homo sapiens	MIA PaCa-2	IC50	2.759	nM	10.6019/CHEMBL1201861
Homo sapiens	MIA PaCa-2	IC50	180.0	nM	10.1016/j.bmc.2017.06.030
Homo sapiens	MIA PaCa-2	IC50	190.0	nM	10.1021/np400433g
Homo sapiens	MIA PaCa-2	IC50	400.0	nM	10.1016/j.bmc.2011.06.067
Homo sapiens	MIA PaCa-2	Inhibition	nan	%	10.1021/acs.jmedchem.7b01463
Homo sapiens	microRNA 21	Potency	104.0	nM	None
Homo sapiens	MKN-1	IC50	37.91	nM	10.6019/CHEMBL1201861
Homo sapiens	MKN-28	IC50	51.21	nM	10.6019/CHEMBL1201861
Homo sapiens	MKN-45	IC50	17.0	nM	10.1021/jm0004751
Homo sapiens	MKN-45	IC50	27.5	nM	10.6019/CHEMBL1201861
Homo sapiens	MKN-7	IC50	144.23	nM	10.6019/CHEMBL1201861
Homo sapiens	ML-2	IC50	2.165	nM	10.6019/CHEMBL1201861
Homo sapiens	MLMA	IC50	8.145	nM	10.6019/CHEMBL1201861
Homo sapiens	MMAC-SF	IC50	38.4	nM	10.6019/CHEMBL1201861
Homo sapiens	MN-60	IC50	5.083	nM	10.6019/CHEMBL1201861
Homo sapiens	Mo	IC50	111.97	nM	10.6019/CHEMBL1201861
Homo sapiens	MOLT-13	IC50	1.787	nM	10.6019/CHEMBL1201861
Homo sapiens	MOLT-16	IC50	0.7318	nM	10.6019/CHEMBL1201861
Homo sapiens	MOLT-4	Activity	nan	None	10.1016/j.bmc.2010.10.042
Homo sapiens	MOLT-4	GI50	10.0	nM	None
Homo sapiens	MOLT-4	IC50	0.04	nM	10.1021/ml400125z
Homo sapiens	MOLT-4	IC50	1.616	nM	10.6019/CHEMBL1201861
Homo sapiens	Monoamine oxidase A	IC50	nan	None	None
Homo sapiens	Monoamine oxidase A	Ki	nan	None	None
Homo sapiens	M-phase phosphoprotein 8	Potency	100000.0	nM	None
Homo sapiens	MPP-89	IC50	27.24	nM	10.6019/CHEMBL1201861
Homo sapiens	MRC5	CC50	200.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	MRC5	CC50	200.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	MRC5	ED50	nan	None	10.1016/j.bmcl.2007.02.051
Homo sapiens	MRC5	IC50	1.7	10^-5 uM	10.1016/j.bmc.2021.116177
Homo sapiens	MRC5	IC50	800.0	nM	10.1016/j.bmcl.2021.128517
Homo sapiens	MRC5	IC50	890.0	nM	10.1021/jm200046z
Homo sapiens	MRC5	IC50	1700.0	nM	10.1016/j.ejmech.2020.112292
Homo sapiens	MRC5	Ratio IC50	0.08	None	10.1021/jm200046z
Homo sapiens	MS-1	IC50	2.774	nM	10.6019/CHEMBL1201861
Homo sapiens	MSTO-211H	IC50	8.238	nM	10.6019/CHEMBL1201861
Homo sapiens	MT4	CC50	4.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	MT4	CC50	10.0	nM	10.1021/jm9707232
Homo sapiens	MT4	IC50	4.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	MT4	IC50	4.0	nM	10.1021/np2009219
Homo sapiens	Multidrug resistance-associated protein 4	IC50	7400.0	nM	10.1093/toxsci/kft176
Homo sapiens	Mu opioid receptor	IC50	nan	None	None
Homo sapiens	Mu opioid receptor	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M1	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M1	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M2	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M2	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M3	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M3	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M4	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M4	Ki	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M5	IC50	nan	None	None
Homo sapiens	Muscarinic acetylcholine receptor M5	Ki	nan	None	None
Homo sapiens	Muscleblind-like protein 1	Potency	2511.9	nM	None
Homo sapiens	Muscleblind-like protein 1	Potency	3162.3	nM	None
Homo sapiens	MV4-11	IC50	0.7058	nM	10.6019/CHEMBL1201861
Homo sapiens	MX1	IC50	1700.0	nM	10.1021/jm500631u
Homo sapiens	MZ1-PC	IC50	20.33	nM	10.6019/CHEMBL1201861
Homo sapiens	MZ2-MEL	IC50	14.11	nM	10.6019/CHEMBL1201861
Homo sapiens	MZ7-mel	IC50	8.612	nM	10.6019/CHEMBL1201861
Homo sapiens	NB10	IC50	0.6143	nM	10.6019/CHEMBL1201861
Homo sapiens	NB12	IC50	44.02	nM	10.6019/CHEMBL1201861
Homo sapiens	NB13	IC50	28.8	nM	10.6019/CHEMBL1201861
Homo sapiens	NB14	IC50	0.9071	nM	10.6019/CHEMBL1201861
Homo sapiens	NB17	IC50	2.175	nM	10.6019/CHEMBL1201861
Homo sapiens	NB-4	IC50	2010.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	NB5	IC50	1.925	nM	10.6019/CHEMBL1201861
Homo sapiens	NB6	IC50	182.71	nM	10.6019/CHEMBL1201861
Homo sapiens	NB69	IC50	0.5694	nM	10.6019/CHEMBL1201861
Homo sapiens	NB7	IC50	16.8	nM	10.6019/CHEMBL1201861
Homo sapiens	NBsusSR	IC50	0.1936	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI/ADR-RES	GI50	11.97	nM	None
Homo sapiens	NCI/ADR-RES	ID50	3.9	nM	10.1016/s0960-894x(02)00153-1
Homo sapiens	NCI-H1048	IC50	0.5292	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1092	IC50	43.18	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1155	IC50	1.188	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H128	IC50	18.0	nM	10.1021/jm0004751
Homo sapiens	NCI-H1299	Activity	5.22	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1299	Activity	9.44	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1299	Activity	13.04	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1299	Activity	13.16	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1299	Activity	nan	None	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1299	GI	nan	None	10.1016/j.ejmech.2017.06.066
Homo sapiens	NCI-H1299	IC50	9.425	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1299	IC50	800.0	nM	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1299	IC50	3140.0	nM	10.1039/C4MD00133H
Homo sapiens	NCI-H1304	IC50	59.28	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1355	IC50	66.1	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1395	IC50	110.1	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1437	IC50	34.93	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1563	IC50	150.37	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1573	IC50	173.4	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1581	IC50	33.5	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1623	IC50	0.7479	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1648	IC50	38.07	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1650	IC50	149.39	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1651	IC50	14.95	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1666	IC50	18.71	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1693	IC50	26.69	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1703	IC50	6.515	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1755	IC50	208.78	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1770	IC50	157.32	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1792	IC50	40.12	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1793	IC50	27.23	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1838	IC50	253.14	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1975	Activity	5.54	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1975	Activity	6.73	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1975	Activity	7.9	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1975	Activity	31.47	%	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1975	Activity	nan	None	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1975	IC50	334.48	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H1975	IC50	1200.0	nM	10.1016/j.bmcl.2017.05.006
Homo sapiens	NCI-H1993	IC50	9621.56	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2009	IC50	68.13	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2029	IC50	491.21	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2030	IC50	48.53	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2052	IC50	28.34	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2087	IC50	5.074	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H209	IC50	0.04843	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2122	IC50	12.98	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2126	IC50	178.42	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2170	IC50	13.71	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2228	IC50	49.0	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H226	GI50	17.95	nM	None
Homo sapiens	NCI-H226	IC50	22.49	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H226	ID50	5.0	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	NCI-H2291	IC50	975.25	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H23	GI50	19.41	nM	None
Homo sapiens	NCI-H23	IC50	40.69	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H23	IC50	70.0	nM	10.1016/j.bmcl.2016.04.056
Homo sapiens	NCI-H2342	IC50	618.33	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2347	IC50	185.61	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2405	IC50	58.48	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H2452	IC50	90.89	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H28	IC50	38.68	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H292	IC50	2.24	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H322M	GI50	106.66	nM	None
Homo sapiens	NCI-H358	IC50	105.42	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H441	IC50	28.46	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H446	IC50	56.63	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H446	IC50	200000.0	nM	10.1021/acs.jmedchem.5b00910
Homo sapiens	NCI-H446	IC50	200000.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	NCI-H460	Activity	1.0	%	10.1016/j.bmc.2010.05.062
Homo sapiens	NCI-H460	EC50	6.9	nM	10.1021/np0496587
Homo sapiens	NCI-H460	GI50	5.7	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	NCI-H460	GI50	15.78	nM	None
Homo sapiens	NCI-H460	GI50	30.0	nM	10.1016/j.bmc.2010.05.062
Homo sapiens	NCI-H460	IC50	2.0	nM	10.1016/j.bmc.2012.06.030
Homo sapiens	NCI-H460	IC50	3.0	nM	10.1021/np300241d
Homo sapiens	NCI-H460	IC50	5.0	nM	10.1016/j.bmcl.2012.06.016
Homo sapiens	NCI-H460	IC50	6.2	nM	10.1021/jm8001982
Homo sapiens	NCI-H460	IC50	13.0	nM	10.1021/jm101354u
Homo sapiens	NCI-H460	IC50	24.12	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H460	IC50	30.0	nM	10.1021/jm200046z
Homo sapiens	NCI-H460	IC50	40.0	nM	10.1021/np200062x
Homo sapiens	NCI-H460	IC50	110.0	nM	10.1021/acsmedchemlett.8b00050
Homo sapiens	NCI-H460	IC50	120.0	nM	10.1016/j.ejmech.2020.112561
Homo sapiens	NCI-H460	IC50	180.0	nM	10.1016/j.bmcl.2008.03.074
Homo sapiens	NCI-H460	IC50	190.0	nM	10.1016/j.bmcl.2016.04.056
Homo sapiens	NCI-H460	IC50	330.0	nM	10.1021/jm000944z
Homo sapiens	NCI-H460	IC50	330.0	nM	10.1021/jm8001982
Homo sapiens	NCI-H460	IC50	330.0	nM	10.1021/jm801153y
Homo sapiens	NCI-H460	IC50	1000.0	nM	10.1021/jm101354u
Homo sapiens	NCI-H460	IC50	5370.0	nM	10.1016/j.ejmech.2019.02.072
Homo sapiens	NCI-H460	IC50	25000.0	nM	10.1016/j.ejmech.2010.05.048
Homo sapiens	NCI-H460	Ratio	77.0	None	10.1021/jm101354u
Homo sapiens	NCI-H460	RatioGI50	33.0	None	10.1016/j.bmc.2010.05.062
Homo sapiens	NCI-H460	Ratio IC50	29.67	None	10.1021/jm200046z
Homo sapiens	NCI-H510A	IC50	1.699	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H520	IC50	162.01	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H522	GI50	22.34	nM	None
Homo sapiens	NCI-H526	IC50	1.028	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H596	IC50	2968.73	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H630	IC50	282.32	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H650	IC50	54.96	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H661	IC50	13.55	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H69	IC50	1.0	nM	10.1021/jm101354u
Homo sapiens	NCI-H69	IC50	311.44	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H720	IC50	44.69	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H727	IC50	1009.34	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H747	IC50	296.49	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H810	IC50	50.3	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-H82	IC50	588.29	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-N87	IC50	8.743	nM	10.6019/CHEMBL1201861
Homo sapiens	NCI-N87	IC50	2320.0	nM	10.1021/acs.jmedchem.2c00968
Homo sapiens	NEC8	IC50	3.108	nM	10.6019/CHEMBL1201861
Homo sapiens	Neurokinin 1 receptor	IC50	nan	None	None
Homo sapiens	Neurokinin 1 receptor	Ki	nan	None	None
Homo sapiens	Neurokinin 2 receptor	IC50	nan	None	None
Homo sapiens	Neurokinin 2 receptor	Ki	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 1	IC50	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 1	Ki	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 2	IC50	nan	None	None
Homo sapiens	Neuropeptide Y receptor type 2	Ki	nan	None	None
Homo sapiens	NH-12	IC50	3.793	nM	10.6019/CHEMBL1201861
Homo sapiens	NHDF	IC50	5380.0	nM	10.1016/j.ejmech.2020.112768
Homo sapiens	NKM-1	IC50	0.441	nM	10.6019/CHEMBL1201861
Homo sapiens	NMC-G1	IC50	19.82	nM	10.6019/CHEMBL1201861
Homo sapiens	no-10	IC50	174.04	nM	10.6019/CHEMBL1201861
Homo sapiens	no-11	IC50	113.08	nM	10.6019/CHEMBL1201861
Homo sapiens	NOMO-1	IC50	1.557	nM	10.6019/CHEMBL1201861
Homo sapiens	Norepinephrine transporter	IC50	nan	None	None
Homo sapiens	Norepinephrine transporter	Ki	nan	None	None
Homo sapiens	NOS-1	IC50	91.86	nM	10.6019/CHEMBL1201861
Homo sapiens	NTERA-2-cl-D1	IC50	0.2738	nM	10.6019/CHEMBL1201861
Homo sapiens	Nuclear factor erythroid 2-related factor 2	Potency	366.3	nM	None
Homo sapiens	Nuclear factor erythroid 2-related factor 2	Potency	461.1	nM	None
Homo sapiens	Nuclear factor erythroid 2-related factor 2	Potency	2059.6	nM	None
Homo sapiens	Nuclear factor NF-kappa-B p105 subunit	Potency	4466.8	nM	None
Homo sapiens	Nuclear receptor subfamily 4 group A member 2	Activity	nan	None	10.1021/acs.jmedchem.0c00894
Homo sapiens	NUGC-3	IC50	3.136	nM	10.6019/CHEMBL1201861
Homo sapiens	NY	IC50	4356.62	nM	10.6019/CHEMBL1201861
Homo sapiens	OAW-28	IC50	7.263	nM	10.6019/CHEMBL1201861
Homo sapiens	OAW-42	IC50	8.99	nM	10.6019/CHEMBL1201861
Homo sapiens	OC-314	IC50	2.506	nM	10.6019/CHEMBL1201861
Homo sapiens	OCI-AML2	IC50	0.8868	nM	10.6019/CHEMBL1201861
Homo sapiens	OCUB-M	IC50	38.13	nM	10.6019/CHEMBL1201861
Homo sapiens	OE19	IC50	3273.33	nM	10.6019/CHEMBL1201861
Homo sapiens	OE33	IC50	25.55	nM	10.6019/CHEMBL1201861
Homo sapiens	OMC-1	IC50	78.21	nM	10.6019/CHEMBL1201861
Homo sapiens	ONS-76	IC50	2.406	nM	10.6019/CHEMBL1201861
Homo sapiens	OS-RC-2	IC50	9.968	nM	10.6019/CHEMBL1201861
Homo sapiens	OVCAR-3	GI50	176.6	nM	None
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm000029d
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm040025z
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm060046o
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm0613119
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm070307+
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm070361q
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm101338z
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm200719v
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm201512x
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm401471v
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm800259e
Homo sapiens	OVCAR-3	GI50	220.0	nM	10.1021/jm901649x
Homo sapiens	OVCAR-3	IC50	956.65	nM	10.6019/CHEMBL1201861
Homo sapiens	OVCAR-4	GI50	209.41	nM	None
Homo sapiens	OVCAR-4	IC50	188.55	nM	10.6019/CHEMBL1201861
Homo sapiens	OVCAR-5	GI50	80.91	nM	None
Homo sapiens	OVCAR-5	IC50	43.33	nM	10.6019/CHEMBL1201861
Homo sapiens	OVCAR-8	GI50	38.82	nM	None
Homo sapiens	OVCAR-8	IC50	7.272	nM	10.6019/CHEMBL1201861
Homo sapiens	P12-Ichikawa	IC50	0.1016	nM	10.6019/CHEMBL1201861
Homo sapiens	P30-OHK	IC50	2.792	nM	10.6019/CHEMBL1201861
Homo sapiens	PA-1	IC50	0.981	nM	10.6019/CHEMBL1201861
Homo sapiens	PANC-03-27	IC50	7.103	nM	10.6019/CHEMBL1201861
Homo sapiens	PANC-08-13	IC50	44.89	nM	10.6019/CHEMBL1201861
Homo sapiens	PANC-1	GI50	6290.0	nM	10.1021/jm300605m
Homo sapiens	PANC-1	IC50	90.0	nM	10.1016/j.bmc.2018.06.032
Homo sapiens	PANC-1	IC50	180.0	nM	10.1016/j.bmc.2018.06.032
Homo sapiens	Panc1005	IC50	19.68	nM	10.6019/CHEMBL1201861
Homo sapiens	Panel (12 tumour cell lines)	IC70	8.6	nM	10.1016/j.bmcl.2006.03.029
Homo sapiens	Panel (Carcinoma cell lines)	Mean graph mid point	0.04	None	10.1021/jm040025z
Homo sapiens	Panel (Carcinoma cell lines)	MGM	0.0405	None	10.1021/jm000029d
Homo sapiens	Panel NCI-60 (60 carcinoma cell lines)	Activity	0.0405	uM	10.1016/j.bmcl.2006.05.048
Homo sapiens	Panel NCI-60 (60 carcinoma cell lines)	GI50	10.0	nM	10.1021/jm049838d
Homo sapiens	PBMC	Activity	nan	None	10.1021/acs.jmedchem.6b01565
Homo sapiens	PBMC	Activity	nan	None	10.1021/acs.jmedchem.6b01870
Homo sapiens	PBMC	Activity	nan	None	10.1021/np200722w
Homo sapiens	PBMC	IC50	10000.0	nM	10.1021/np400672g
Homo sapiens	PC-14	IC50	13.58	nM	10.6019/CHEMBL1201861
Homo sapiens	PC-3	Activity	4.76	%	10.1016/j.ejmech.2013.01.003
Homo sapiens	PC-3	Activity	4.76	%	10.1016/j.ejmech.2014.05.053
Homo sapiens	PC-3	Activity	4.94	%	10.1016/j.ejmech.2013.01.003
Homo sapiens	PC-3	Activity	4.94	%	10.1016/j.ejmech.2014.05.053
Homo sapiens	PC-3	Activity	30.17	%	10.1016/j.ejmech.2013.01.003
Homo sapiens	PC-3	Activity	30.17	%	10.1016/j.ejmech.2014.05.053
Homo sapiens	PC-3	Activity	60.44	%	10.1016/j.ejmech.2013.01.003
Homo sapiens	PC-3	Activity	60.44	%	10.1016/j.ejmech.2014.05.053
Homo sapiens	PC-3	Activity	nan	None	10.1016/j.bmcl.2014.08.010
Homo sapiens	PC-3	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	PC-3	ED50	16.7	nM	10.1016/j.bmcl.2007.02.051
Homo sapiens	PC-3	FC	0.258	None	10.1038/nchembio790
Homo sapiens	PC-3	GI	nan	None	10.1016/j.ejmech.2017.06.066
Homo sapiens	PC-3	GI50	60.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	PC-3	GI50	64.42	nM	None
Homo sapiens	PC-3	GI50	90.0	nM	10.1016/j.bmc.2007.12.028
Homo sapiens	PC-3	GI50	90.0	nM	10.1021/jm1005447
Homo sapiens	PC-3	GI50	480.0	nM	10.1021/jm1009428
Homo sapiens	PC-3	GI50	700.0	nM	10.1021/jm900469e
Homo sapiens	PC-3	GI50	287000.0	nM	10.1021/jm300605m
Homo sapiens	PC-3	IC50	9.753	nM	10.6019/CHEMBL1201861
Homo sapiens	PC-3	IC50	10.0	nM	10.1021/np400483c
Homo sapiens	PC-3	IC50	12.0	nM	10.1021/jm101354u
Homo sapiens	PC-3	IC50	30.0	nM	10.1016/j.bmc.2010.10.042
Homo sapiens	PC-3	IC50	52.0	nM	10.1021/jm051247f
Homo sapiens	PC-3	IC50	57.0	nM	10.1021/jm980400l
Homo sapiens	PC-3	IC50	78.0	nM	10.1021/ml400125z
Homo sapiens	PC-3	IC50	100.0	nM	10.1016/j.ejmech.2014.09.050
Homo sapiens	PC-3	IC50	310.0	nM	10.1016/j.bmcl.2004.01.097
Homo sapiens	PC-3	IC50	400.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	PC-3	IC50	1200.0	nM	10.1021/np400433g
Homo sapiens	PC-3	IC50	1200.0	nM	10.1039/C4MD00344F
Homo sapiens	PC-3	IC50	1400.0	nM	10.1021/jm900469e
Homo sapiens	PC-3	IC50	1414.4	nM	10.1016/j.bmcl.2004.08.010
Homo sapiens	PC-3	IC50	2400.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	PC-3	IC50	2500.0	nM	10.1021/acs.jmedchem.5b00910
Homo sapiens	PC-3	IC50	6960.0	nM	10.1021/acs.jnatprod.7b00387
Homo sapiens	PC-3	IC50	16240.0	nM	10.1016/j.bmc.2010.10.019
Homo sapiens	PC-3	IC50	18240.0	nM	10.1039/C8MD00278A
Homo sapiens	PC-3	IC50	40000.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	PC-3	ID50	3.8	nM	10.1016/s0960-894x(02)00153-1
Homo sapiens	PC-3	LC50	100000.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	PC-3	TGI	100000.0	nM	10.1016/j.ejmech.2010.11.013
Homo sapiens	PC-3M	IC50	190.0	nM	10.1021/acs.jmedchem.2c00204
Homo sapiens	PC-3M	IC50	480.0	nM	10.1021/acs.jmedchem.2c00204
Homo sapiens	Peregrin	Delta TM	-2.28	C	None
Homo sapiens	Peripheral myelin protein 22	Potency	239.3	nM	None
Homo sapiens	PFSK-1	IC50	26.03	nM	10.6019/CHEMBL1201861
Homo sapiens	P-glycoprotein 1	Activity	nan	None	10.1023/a:1022242607418
Homo sapiens	Phosphodiesterase 5A	IC50	nan	None	None
Homo sapiens	Phosphodiesterase 5A	Ki	nan	None	None
Homo sapiens	Plasma	Activity	3.8	%	10.1016/j.ejmech.2008.01.008
Homo sapiens	Plasma	Activity	14.6	%	10.1016/j.ejmech.2008.01.008
Homo sapiens	Plasma	Activity	19.4	%	10.1016/j.ejmech.2008.01.008
Homo sapiens	Plasma	Activity	28.4	%	10.1016/j.ejmech.2008.01.008
Homo sapiens	Plasma	Activity	61.4	%	10.1016/j.ejmech.2008.01.008
Homo sapiens	Platelet activating factor receptor	IC50	nan	None	None
Homo sapiens	Platelet activating factor receptor	Ki	nan	None	None
Homo sapiens	Prelamin-A/C	Potency	5.6	nM	None
Homo sapiens	Prelamin-A/C	Potency	15.8	nM	None
Homo sapiens	Prelamin-A/C	Potency	25.1	nM	None
Homo sapiens	Protein kinase C alpha	IC50	nan	None	None
Homo sapiens	Protein kinase C alpha	Ki	nan	None	None
Homo sapiens	PSN1	IC50	3.069	nM	10.6019/CHEMBL1201861
Homo sapiens	QG-56	IC50	0.00463	ug.mL-1	10.1021/jm00045a007
Homo sapiens	QG-56	IC50	0.00463	ug.mL-1	10.1021/jm970765q
Homo sapiens	QIMR-WIL	IC50	0.7753	nM	10.6019/CHEMBL1201861
Homo sapiens	Raji	IC50	1000.0	nM	10.1021/np900827a
Homo sapiens	Raji	IC50	3270.0	nM	10.1039/C8MD00278A
Homo sapiens	Ramos-2G6-4C10	IC50	10.51	nM	10.6019/CHEMBL1201861
Homo sapiens	Ras-related protein Rab-9A	Potency	398.1	nM	None
Homo sapiens	Ras-related protein Rab-9A	Potency	46109.1	nM	None
Homo sapiens	RCC10RGB	IC50	113.62	nM	10.6019/CHEMBL1201861
Homo sapiens	RCM-1	IC50	28.66	nM	10.6019/CHEMBL1201861
Homo sapiens	RD	Activity	0.67	%	10.1016/j.ejmech.2013.07.016
Homo sapiens	RD	Activity	3.1	%	10.1016/j.ejmech.2013.07.016
Homo sapiens	RD	Activity	4.08	%	10.1016/j.ejmech.2013.07.016
Homo sapiens	RD	Activity	92.16	%	10.1016/j.ejmech.2013.07.016
Homo sapiens	RD	IC50	15.74	nM	10.6019/CHEMBL1201861
Homo sapiens	RD	IC50	1240.0	nM	10.1016/j.ejmech.2017.09.005
Homo sapiens	RD	IC50	1720.0	nM	10.1016/j.bmcl.2018.10.014
Homo sapiens	RD	IC50	4490.0	nM	10.1016/j.ejmech.2017.09.009
Homo sapiens	Receptor protein-tyrosine kinase erbB-2	IC50	nan	None	None
Homo sapiens	Receptor protein-tyrosine kinase erbB-2	Ki	nan	None	None
Homo sapiens	Regulator of G-protein signaling 4	Potency	2667.9	nM	None
Homo sapiens	Relaxin receptor 1	Potency	12589.3	nM	None
Homo sapiens	RERF-LC-MS	IC50	22.87	nM	10.6019/CHEMBL1201861
Homo sapiens	RH-1	IC50	3.86	nM	10.6019/CHEMBL1201861
Homo sapiens	RH-18	IC50	389.64	nM	10.6019/CHEMBL1201861
Homo sapiens	RKO	Activity	nan	None	10.1021/acs.jmedchem.2c00635
Homo sapiens	RKO	IC50	4.23	nM	10.6019/CHEMBL1201861
Homo sapiens	RKO	IC50	61.7	nM	10.1021/acs.jmedchem.2c00635
Homo sapiens	RKO	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	RMG-I	IC50	244.5	nM	10.6019/CHEMBL1201861
Homo sapiens	RO82-W-1	IC50	14.91	nM	10.6019/CHEMBL1201861
Homo sapiens	RPMI-2650	IC50	2.217	nM	10.6019/CHEMBL1201861
Homo sapiens	RPMI-7951	IC50	4.753	nM	10.6019/CHEMBL1201861
Homo sapiens	RPMI-7951	IC50	220.0	nM	10.1021/acsmedchemlett.0c00131
Homo sapiens	RPMI-8226	GI50	33.65	nM	None
Homo sapiens	RPMI-8226	IC50	2.05	ug.mL-1	10.1016/j.ejmech.2015.03.033
Homo sapiens	RPMI-8226	IC50	6.0	nM	10.1016/j.ejmech.2008.09.048
Homo sapiens	RPMI-8226	IC50	29.49	nM	10.6019/CHEMBL1201861
Homo sapiens	RPMI 8402	IC50	5.0	nM	10.1021/jm020498a
Homo sapiens	RPMI 8402	IC50	6.0	nM	10.1016/j.bmcl.2004.08.070
Homo sapiens	RPMI 8402	IC50	10000.0	nM	10.1016/j.bmcl.2004.08.070
Homo sapiens	RPMI-8866	IC50	1.725	nM	10.6019/CHEMBL1201861
Homo sapiens	RS4-11	IC50	0.9022	nM	10.6019/CHEMBL1201861
Homo sapiens	RT-112	IC50	14.88	nM	10.6019/CHEMBL1201861
Homo sapiens	RVH-421	IC50	71.47	nM	10.6019/CHEMBL1201861
Homo sapiens	RXF 393	GI50	25.64	nM	None
Homo sapiens	RXF 393	IC50	4.662	nM	10.6019/CHEMBL1201861
Homo sapiens	S-117	IC50	78.15	nM	10.6019/CHEMBL1201861
Homo sapiens	SAOS-2	GI50	287000.0	nM	10.1021/jm300605m
Homo sapiens	SAOS-2	IC50	17.77	nM	10.6019/CHEMBL1201861
Homo sapiens	SAS	GI50	6000.0	nM	10.1016/j.bmc.2007.12.028
Homo sapiens	SAS	GI50	6000.0	nM	10.1021/jm1005447
Homo sapiens	SAS	IC50	1.241	nM	10.6019/CHEMBL1201861
Homo sapiens	SAS	IC50	6000.0	nM	10.1039/C4MD00133H
Homo sapiens	SAS	RatioGI50	0.17	None	10.1021/jm1005447
Homo sapiens	SBC-1	IC50	27.79	nM	10.6019/CHEMBL1201861
Homo sapiens	SBC-5	IC50	32.15	nM	10.6019/CHEMBL1201861
Homo sapiens	SCC-15	IC50	18.57	nM	10.6019/CHEMBL1201861
Homo sapiens	SCC-25	IC50	56.73	nM	10.6019/CHEMBL1201861
Homo sapiens	SCC-4	IC50	19.26	nM	10.6019/CHEMBL1201861
Homo sapiens	SCC-9	IC50	33.19	nM	10.6019/CHEMBL1201861
Homo sapiens	SCH	IC50	628.09	nM	10.6019/CHEMBL1201861
Homo sapiens	Serine/threonine-protein kinase Aurora-A	Delta TM	-0.49	C	None
Homo sapiens	Serine/threonine-protein kinase Chk1	Activity	4.7	%	10.1021/jm070105d
Homo sapiens	Serine/threonine-protein kinase Chk1	Activity	9.5	%	10.1021/jm070105d
Homo sapiens	Serine/threonine-protein kinase Chk1	Activity	32.9	%	10.1021/jm070105d
Homo sapiens	Serine/threonine-protein kinase Chk1	Activity	43.1	%	10.1021/jm070105d
Homo sapiens	Serine/threonine-protein kinase Chk1	EC50	2.1	nM	10.1016/j.bmc.2007.01.012
Homo sapiens	Serine/threonine-protein kinase mTOR	Potency	46.5	nM	None
Homo sapiens	Serine/threonine-protein kinase mTOR	Potency	104.0	nM	None
Homo sapiens	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	IC50	nan	None	None
Homo sapiens	Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform	Ki	nan	None	None
Homo sapiens	Serotonin 2a (5-HT2a) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2a (5-HT2a) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 2b (5-HT2b) receptor	IC50	970.0	nM	None
Homo sapiens	Serotonin 2b (5-HT2b) receptor	Ki	617.0	nM	None
Homo sapiens	Serotonin 2c (5-HT2c) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 2c (5-HT2c) receptor	Ki	nan	None	None
Homo sapiens	Serotonin 6 (5-HT6) receptor	IC50	nan	None	None
Homo sapiens	Serotonin 6 (5-HT6) receptor	Ki	nan	None	None
Homo sapiens	Serotonin transporter	IC50	nan	None	None
Homo sapiens	Serotonin transporter	Ki	nan	None	None
Homo sapiens	Serotransferrin	Activity	nan	None	10.1016/j.bmcl.2014.10.048
Homo sapiens	Serotransferrin	KSV	2.624	10'4L/mol	10.1016/j.bmcl.2014.10.048
Homo sapiens	Serotransferrin	KSV	4.353	10'4L/mol	10.1016/j.bmcl.2014.10.048
Homo sapiens	Serum albumin	Activity	1.8	None	10.1021/jm00027a005
Homo sapiens	Serum albumin	Activity	2.3	None	10.1021/jm00027a005
Homo sapiens	Serum albumin	K	30.0	1/Maa	10.1021/jm00027a005
Homo sapiens	Serum albumin	K	4700.0	1/Maa	10.1021/jm00027a005
Homo sapiens	Serum albumin	Log K'	0.08	None	10.1021/jm010960b
Homo sapiens	SF-126	IC50	2.835	nM	10.6019/CHEMBL1201861
Homo sapiens	SF-268	Activity	25.0	%	10.1016/j.bmc.2010.05.062
Homo sapiens	SF-268	EC50	59.0	nM	10.1021/np0496587
Homo sapiens	SF-268	GI50	10.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	SF-268	GI50	10.0	nM	10.1021/jm0613119
Homo sapiens	SF-268	GI50	11.51	nM	None
Homo sapiens	SF-268	GI50	190.0	nM	10.1016/j.bmc.2010.05.062
Homo sapiens	SF-268	IC50	3.379	nM	10.6019/CHEMBL1201861
Homo sapiens	SF-268	IC50	40.0	nM	10.1021/np200062x
Homo sapiens	SF-268	IC50	70.0	nM	10.1016/j.bmc.2012.06.030
Homo sapiens	SF-268	IC50	190.0	nM	10.1021/jm200046z
Homo sapiens	SF-268	RatioGI50	5.21	None	10.1016/j.bmc.2010.05.062
Homo sapiens	SF-268	Ratio IC50	4.68	None	10.1021/jm200046z
Homo sapiens	SF-295	GI50	11.53	nM	None
Homo sapiens	SF-295	IC50	7.909	nM	10.6019/CHEMBL1201861
Homo sapiens	SF-539	GI50	10.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	SF-539	GI50	10.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm000029d
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm060046o
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm070307+
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm070361q
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm101338z
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm200719v
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm201512x
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm401471v
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm800259e
Homo sapiens	SF-539	GI50	10.0	nM	10.1021/jm901649x
Homo sapiens	SF-539	GI50	14.49	nM	None
Homo sapiens	SF-539	IC50	9.009	nM	10.6019/CHEMBL1201861
Homo sapiens	SGC-7901	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	SGC-7901	IC50	5800.0	nM	10.1021/acs.jmedchem.2c00635
Homo sapiens	SH-4	IC50	59.8	nM	10.6019/CHEMBL1201861
Homo sapiens	SHP77	IC50	1543.63	nM	10.6019/CHEMBL1201861
Homo sapiens	SH-SY5Y	IC50	610.0	nM	10.1021/acs.jmedchem.2c00615
Homo sapiens	SH-SY5Y	Potency	1778.3	nM	None
Homo sapiens	Sigma opioid receptor	IC50	nan	None	None
Homo sapiens	Sigma opioid receptor	Ki	nan	None	None
Homo sapiens	SiHa	GI50	550.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	SiHa	IC50	86.88	nM	10.6019/CHEMBL1201861
Homo sapiens	SJRH30	IC50	298.06	nM	10.6019/CHEMBL1201861
Homo sapiens	SJSA-1	IC50	18.0	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-BR-3	Activity	0.35	%	10.1021/acs.jmedchem.2c00968
Homo sapiens	SK-BR-3	Activity	12.3	%	10.1021/acs.jmedchem.2c00968
Homo sapiens	SK-BR-3	Activity	38.6	%	10.1021/acs.jmedchem.2c00968
Homo sapiens	SK-BR-3	Activity	48.8	%	10.1021/acs.jmedchem.2c00968
Homo sapiens	SK-BR-3	Activity	50.8	%	10.1021/acs.jmedchem.2c00968
Homo sapiens	SK-BR-3	GI50	150.0	nM	10.1021/np9006734
Homo sapiens	SK-BR-3	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	SK-BR-3	IC50	20.0	nM	10.1021/jm0004751
Homo sapiens	SK-BR-3	IC50	210.0	nM	10.1021/acs.jmedchem.2c00968
Homo sapiens	SKG-IIIa	IC50	4.582	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-HEP1	IC50	7.253	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-HEP1	IC50	900.0	nM	10.1021/acs.jmedchem.9b01626
Homo sapiens	SK-LMS-1	IC50	180.87	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-LU-1	IC50	4.713	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL	GI50	47.0	nM	10.1021/jm1009428
Homo sapiens	SK-MEL-1	IC50	51.29	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL-2	GI50	297.85	nM	None
Homo sapiens	SK-MEL-2	IC50	6.88	ug.mL-1	10.1016/j.bmc.2011.05.012
Homo sapiens	SK-MEL-2	IC50	54.75	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL-2	IC50	75.0	nM	10.1016/j.bmcl.2007.08.062
Homo sapiens	SK-MEL-2	IC50	165.0	nM	10.1016/j.ejmech.2007.05.002
Homo sapiens	SK-MEL-2	IC50	7860.0	nM	10.1016/j.bmc.2011.08.006
Homo sapiens	SK-MEL-2	IC50	nan	nM	10.1016/j.bmcl.2003.09.001
Homo sapiens	SK-MEL-24	IC50	38.51	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL-24	IC50	460.0	nM	10.1021/acsmedchemlett.0c00131
Homo sapiens	SK-MEL-28	Activity	nan	None	10.1016/j.ejmech.2022.114465
Homo sapiens	SK-MEL-28	CC50	70.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	SK-MEL-28	CC50	70.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	SK-MEL-28	GI50	227.51	nM	None
Homo sapiens	SK-MEL-28	IC50	10.0	nM	10.1021/np400483c
Homo sapiens	SK-MEL-28	IC50	17.13	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL-28	IC50	40.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	SK-MEL-28	IC50	2260.0	nM	10.1016/j.ejmech.2022.114465
Homo sapiens	SK-MEL3	IC50	329.41	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL-30	IC50	2281.97	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-MEL-5	GI50	27.16	nM	None
Homo sapiens	SK-MES-1	CC50	30.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	SK-MES-1	CC50	50.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	SK-MES-1	IC50	10.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	SK-MES-1	IC50	10.78	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-N-AS	IC50	5.377	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-N-BE(2)	Activity	nan	None	10.1021/acs.jmedchem.0c00894
Homo sapiens	SK-N-DZ	IC50	21.69	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-NEP-1	IC50	1.227	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-N-FI	IC50	106.62	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-OV-3	Activity	0.035	ug ml-1	10.1016/j.bmcl.2009.03.042
Homo sapiens	SK-OV-3	GI50	20.18	nM	None
Homo sapiens	SK-OV-3	IC50	1.54	ug.mL-1	10.1016/j.bmc.2011.05.012
Homo sapiens	SK-OV-3	IC50	5.5	nM	10.1016/j.bmc.2021.116177
Homo sapiens	SK-OV-3	IC50	5.5	nM	10.1016/j.bmcl.2021.128517
Homo sapiens	SK-OV-3	IC50	5.5	nM	10.1016/j.ejmech.2018.02.058
Homo sapiens	SK-OV-3	IC50	5.5	nM	10.1016/j.ejmech.2019.06.032
Homo sapiens	SK-OV-3	IC50	14.0	nM	10.1016/j.ejmech.2007.05.002
Homo sapiens	SK-OV-3	IC50	20.0	nM	10.1021/jm0004751
Homo sapiens	SK-OV-3	IC50	37.0	nM	10.1021/jm00003a001
Homo sapiens	SK-OV-3	IC50	51.0	nM	10.1021/jm9605804
Homo sapiens	SK-OV-3	IC50	2544.0	nM	10.1016/j.bmc.2011.08.006
Homo sapiens	SK-OV-3	IC50	2560.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	SK-OV-3	IC50	3820.0	nM	10.1021/acs.jmedchem.2c00968
Homo sapiens	SK-OV-3	IC50	4860.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	SK-OV-3	IC50	5500.0	nM	10.1016/j.ejmech.2020.112292
Homo sapiens	SK-OV-3	IC50	7210.91	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-OV-3	IC50	nan	nM	10.1016/j.bmcl.2003.09.001
Homo sapiens	SK-PN-DW	IC50	1.16	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-UT-1	IC50	3.067	nM	10.6019/CHEMBL1201861
Homo sapiens	SK-VLB	IC50	41.0	nM	10.1021/jm00003a001
Homo sapiens	SK-VLB	IC50	53.0	nM	10.1021/jm9605804
Homo sapiens	SMMC-7721	IC50	3.0	nM	10.1021/np2002918
Homo sapiens	SMMC-7721	IC50	20.0	nM	10.1016/j.bmc.2010.10.019
Homo sapiens	SMMC-7721	IC50	450.0	nM	10.1016/j.bmcl.2018.11.049
Homo sapiens	SMMC-7721	IC50	1080.0	nM	10.1016/j.ejmech.2018.08.021
Homo sapiens	SMMC-7721	IC50	10000.0	nM	10.1021/acs.jmedchem.1c01362
Homo sapiens	SMMC-7721	Inhibition	nan	%	10.1016/j.bmcl.2014.10.048
Homo sapiens	SN12C	GI50	14.03	nM	None
Homo sapiens	SN12C	GI50	20.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	SN12C	GI50	20.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	SN12C	GI50	20.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/acs.jmedchem.6b00003
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm000029d
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm040025z
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm060046o
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm0613119
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm070307+
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm070361q
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm101338z
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm200719v
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm201512x
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm401471v
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm500294a
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm800259e
Homo sapiens	SN12C	GI50	20.0	nM	10.1021/jm901649x
Homo sapiens	SN12C	IC50	4.503	nM	10.6019/CHEMBL1201861
Homo sapiens	SN12K1	GI50	24.49	nM	None
Homo sapiens	SNB-19	GI50	18.16	nM	None
Homo sapiens	SNB-75	GI50	27.16	nM	None
Homo sapiens	SNB-75	IC50	17.34	nM	10.6019/CHEMBL1201861
Homo sapiens	SNB-78	GI50	332.66	nM	None
Homo sapiens	SNU1	IC50	1.088	nM	10.6019/CHEMBL1201861
Homo sapiens	SNU-387	IC50	256.33	nM	10.6019/CHEMBL1201861
Homo sapiens	SNU-423	IC50	128.79	nM	10.6019/CHEMBL1201861
Homo sapiens	SNU-449	IC50	194.29	nM	10.6019/CHEMBL1201861
Homo sapiens	SNU-5	IC50	42.71	nM	10.6019/CHEMBL1201861
Homo sapiens	SNU-638	IC50	98.0	nM	10.1016/j.bmc.2010.10.057
Homo sapiens	SNU-638	IC50	98.0	nM	10.1016/j.bmc.2011.01.064
Homo sapiens	SNU-638	IC50	98.0	nM	10.1016/j.bmcl.2007.04.064
Homo sapiens	SNU-638	IC50	280.0	nM	10.1016/j.bmcl.2013.03.106
Homo sapiens	SNU-C2B	IC50	35.38	nM	10.6019/CHEMBL1201861
Homo sapiens	Solute carrier organic anion transporter family member 1B1	Inhibition	74.81	%	10.1124/mol.112.084152
Homo sapiens	Solute carrier organic anion transporter family member 1B3	Inhibition	107.28	%	10.1124/mol.112.084152
Homo sapiens	Somatostatin receptor	IC50	2.21	nM	10.1016/s0960-894x(03)00016-7
Homo sapiens	SR	GI50	10.0	nM	None
Homo sapiens	SU-DHL-2	IC50	940.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	Survival motor neuron protein	Potency	28.2	nM	None
Homo sapiens	Survival motor neuron protein	Potency	31.6	nM	None
Homo sapiens	Survival motor neuron protein	Potency	35.5	nM	None
Homo sapiens	SW1088	IC50	27.77	nM	10.6019/CHEMBL1201861
Homo sapiens	SW 1116	IC50	190.35	nM	10.6019/CHEMBL1201861
Homo sapiens	SW13	IC50	2.993	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1417	IC50	52.7	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1463	IC50	51.69	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1573	GI50	210.0	nM	10.1016/j.bmc.2009.07.053
Homo sapiens	SW1573	GI50	250.0	nM	10.1016/j.ejmech.2013.06.013
Homo sapiens	SW1573	IC50	2.348	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1710	IC50	33.57	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1783	IC50	24.57	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1990	IC50	37.88	nM	10.6019/CHEMBL1201861
Homo sapiens	SW1990	IC50	200.0	nM	10.1016/j.ejmech.2020.112509
Homo sapiens	SW48	IC50	3.017	nM	10.6019/CHEMBL1201861
Homo sapiens	SW480	Activity	nan	None	10.1016/j.bmc.2020.115443
Homo sapiens	SW480	FC	0.3	None	10.1016/j.bmc.2020.115443
Homo sapiens	SW480	IC50	0.01	ug.mL-1	10.1016/S0960-894X(01)80158-X
Homo sapiens	SW480	IC50	210.0	nM	10.1016/j.bmc.2020.115443
Homo sapiens	SW480	IC50	290.0	nM	10.1016/j.bmcl.2018.11.049
Homo sapiens	SW480	IC50	nan	None	10.1016/j.ejmech.2022.114376
Homo sapiens	SW-620	Activity	60.0	%	10.1016/j.ejmech.2011.04.030
Homo sapiens	SW-620	Activity	nan	None	10.1016/j.ejmech.2011.04.030
Homo sapiens	SW-620	EC50	0.15	nM	10.1021/jm048989d
Homo sapiens	SW-620	EC50	1.2	nM	10.1021/jm048989d
Homo sapiens	SW-620	GI50	36.64	nM	None
Homo sapiens	SW-620	IC50	4.082	nM	10.6019/CHEMBL1201861
Homo sapiens	SW626	IC50	28.7	nM	10.1021/np010420h
Homo sapiens	SW626	IC50	76.9	nM	10.6019/CHEMBL1201861
Homo sapiens	SW684	IC50	711.49	nM	10.6019/CHEMBL1201861
Homo sapiens	SW756	IC50	4.211	nM	10.6019/CHEMBL1201861
Homo sapiens	SW780	IC50	25.78	nM	10.6019/CHEMBL1201861
Homo sapiens	SW837	IC50	48.92	nM	10.6019/CHEMBL1201861
Homo sapiens	SW872	IC50	24.16	nM	10.6019/CHEMBL1201861
Homo sapiens	SW900	IC50	31.84	nM	10.6019/CHEMBL1201861
Homo sapiens	SW948	IC50	160.0	nM	10.1021/np900312u
Homo sapiens	SW948	IC50	260.2	nM	10.6019/CHEMBL1201861
Homo sapiens	SW 954	IC50	20.35	nM	10.6019/CHEMBL1201861
Homo sapiens	SW 962	IC50	20.51	nM	10.6019/CHEMBL1201861
Homo sapiens	SW982	IC50	4.062	nM	10.6019/CHEMBL1201861
Homo sapiens	T-24	IC50	1.614	nM	10.6019/CHEMBL1201861
Homo sapiens	T-24	IC50	6.0	nM	10.1016/j.bmc.2006.12.010
Homo sapiens	T-24	IC50	88.0	nM	10.1016/j.ejmech.2013.01.058
Homo sapiens	T-24	IC50	88.0	nM	10.1021/jm000129j
Homo sapiens	T-24	IC50	3090.0	nM	10.1016/j.ejmech.2019.02.072
Homo sapiens	T-24	IC50	6800.0	nM	10.1016/j.ejmech.2019.01.004
Homo sapiens	T-24	Inhibition	15.4	%	10.1016/j.ejmech.2008.01.008
Homo sapiens	T47D	GI50	22.54	nM	None
Homo sapiens	T47D	GI50	1900.0	nM	10.1016/j.bmc.2009.07.053
Homo sapiens	T47D	GI50	2000.0	nM	10.1016/j.ejmech.2013.06.013
Homo sapiens	T47D	GI50	2000.0	nM	10.1021/np9006734
Homo sapiens	T47D	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	T47D	IC50	13.52	nM	10.6019/CHEMBL1201861
Homo sapiens	T47D	IC50	70.0	nM	10.1016/j.bmc.2018.09.021
Homo sapiens	T47D	IC50	70.0	nM	10.1016/j.bmcl.2013.03.106
Homo sapiens	T47D	IC50	70.0	nM	10.1016/j.bmcl.2018.01.048
Homo sapiens	T47D	IC50	80.0	nM	10.1016/j.bmc.2015.08.018
Homo sapiens	T47D	IC50	90.0	nM	10.1016/j.ejmech.2021.113916
Homo sapiens	T47D	IC50	207.0	nM	10.1021/jm00003a001
Homo sapiens	T47D	IC50	250.0	nM	10.1021/acs.jmedchem.9b00970
Homo sapiens	T47D	IC50	280.0	nM	10.1016/j.ejmech.2014.05.047
Homo sapiens	T47D	IC50	300.0	nM	10.1016/j.ejmech.2013.07.048
Homo sapiens	T47D	IC50	310.0	nM	10.1016/j.bmc.2015.04.031
Homo sapiens	T47D	IC50	490.0	nM	10.1016/j.bmc.2018.02.035
Homo sapiens	T47D	IC50	750.0	nM	10.1016/j.ejmech.2014.07.058
Homo sapiens	T47D	IC50	1000.0	nM	10.1016/j.bmc.2012.07.016
Homo sapiens	T47D	IC50	1530.0	nM	10.1016/j.ejmech.2012.03.010
Homo sapiens	T47D	IC50	1620.0	nM	10.1016/j.ejmech.2015.08.040
Homo sapiens	T47D	IC50	1840.0	nM	10.1016/j.bmc.2015.04.002
Homo sapiens	T47D	IC50	1840.0	nM	10.1016/j.ejmech.2016.02.050
Homo sapiens	T47D	IC50	2100.0	nM	10.1016/j.ejmech.2017.01.003
Homo sapiens	T47D	IC50	2100.0	nM	10.1016/j.ejmech.2017.03.048
Homo sapiens	T47D	IC50	2310.0	nM	10.1016/j.bmcl.2017.06.025
Homo sapiens	T47D	IC50	3670.0	nM	10.1016/j.bmc.2016.09.051
Homo sapiens	T47D	IC50	4100.0	nM	10.1016/j.bmc.2016.03.017
Homo sapiens	T47D	IC50	9170.0	nM	10.1016/j.bmc.2012.06.034
Homo sapiens	T47D	IC50	11170.0	nM	10.1016/j.bmcl.2016.02.053
Homo sapiens	T84	IC50	4602.33	nM	10.6019/CHEMBL1201861
Homo sapiens	T98G	IC50	27.15	nM	10.6019/CHEMBL1201861
Homo sapiens	TCC-SUP	IC50	39.04	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-1	IC50	35.11	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-10	IC50	147.61	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-11	IC50	16.33	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-12	IC50	265.25	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-5	IC50	7.38	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-6	IC50	178.5	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-8	IC50	4.17	nM	10.6019/CHEMBL1201861
Homo sapiens	TE-9	IC50	23.65	nM	10.6019/CHEMBL1201861
Homo sapiens	Telomerase reverse transcriptase	IC50	300000.0	nM	10.1021/np0004606
Homo sapiens	TERT-RPE1	Activity	nan	None	10.1021/acs.jnatprod.6b00750
Homo sapiens	TERT-RPE1	IC50	27200.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	TERT-RPE1	IC50	40000.0	nM	10.1016/j.ejmech.2017.11.078
Homo sapiens	TGBC11TKB	IC50	12.24	nM	10.6019/CHEMBL1201861
Homo sapiens	TGBC1TKB	IC50	109.97	nM	10.6019/CHEMBL1201861
Homo sapiens	TGBC24TKB	IC50	53.71	nM	10.6019/CHEMBL1201861
Homo sapiens	THP-1	EC50	160.0	nM	10.1021/np900681y
Homo sapiens	THP-1	IC50	71.0	nM	10.1016/j.ejmech.2012.01.014
Homo sapiens	THP-1	IC50	600.0	nM	10.1021/jm900469e
Homo sapiens	THP-1	IC50	1890.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	THP-1	LD50	0.16	umol/L	10.1016/j.bmc.2013.08.030
Homo sapiens	THP-1	LD50	0.161	uM	10.1016/j.bmcl.2018.05.011
Homo sapiens	Thrombopoietin	Potency	125.9	nM	None
Homo sapiens	Thromboxane-A synthase	IC50	nan	None	None
Homo sapiens	Thromboxane-A synthase	Ki	nan	None	None
Homo sapiens	Thyroid stimulating hormone receptor	Potency	39810.7	nM	None
Homo sapiens	TI-73	IC50	14.55	nM	10.6019/CHEMBL1201861
Homo sapiens	TK-10	GI50	1324.34	nM	None
Homo sapiens	TK-10	IC50	55.79	nM	10.6019/CHEMBL1201861
Homo sapiens	Topoisomerase I/II	Inhibition	74.6	%	10.1016/j.ejmech.2017.01.003
Homo sapiens	Topoisomerase I/II	Inhibition	80.5	%	10.1016/j.ejmech.2017.01.003
Homo sapiens	Transcription intermediary factor 1-alpha	Delta TM	-0.62	C	None
Homo sapiens	Tubulin beta	Inhibition	nan	%	10.1016/j.ejmech.2020.112870
Homo sapiens	Tumor Cell line	GI50	44.0	nM	10.1021/jm000144o
Homo sapiens	TYK-nu	IC50	4.94	nM	10.6019/CHEMBL1201861
Homo sapiens	Tyrosine-protein kinase ABL	Delta TM	0.57	C	None
Homo sapiens	Tyrosine-protein kinase FYN	IC50	nan	None	None
Homo sapiens	Tyrosine-protein kinase FYN	Ki	nan	None	None
Homo sapiens	Tyrosine-protein kinase LCK	IC50	nan	None	None
Homo sapiens	Tyrosine-protein kinase LCK	Ki	nan	None	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	IC50	0.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	IC50	111000.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	IC50	nan	None	10.1021/acs.jmedchem.1c00318
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	IC50	nan	None	10.1021/acs.jmedchem.5b00136
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Inhibition	nan	%	10.1021/acs.jmedchem.8b00639
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	18.4	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	33.5	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	37.6	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	79.4	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	89.1	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 1	Potency	231.1	nM	None
Homo sapiens	Tyrosyl-DNA phosphodiesterase 2	IC50	0.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	Tyrosyl-DNA phosphodiesterase 2	IC50	111000.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	U-118-MG	IC50	19.0	nM	10.6019/CHEMBL1201861
Homo sapiens	U-251	GI50	10.0	nM	10.1021/acs.jmedchem.7b01797
Homo sapiens	U-251	GI50	11.07	nM	None
Homo sapiens	U-251	IC50	1.869	nM	10.6019/CHEMBL1201861
Homo sapiens	U-266	IC50	69.51	nM	10.6019/CHEMBL1201861
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Growth Rate	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Growth Rate	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	88.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	63.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	75.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	99.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	139.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	156.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	178.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	199.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	276.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	GI50	287000.0	nM	10.1021/jm300605m
Homo sapiens	U2OS	Growth Rate	-0.34	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	-0.11	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.2	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.33	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.48	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.59	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.64	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.7	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.75	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.82	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	IC50	13.54	nM	10.6019/CHEMBL1201861
Homo sapiens	U2OS	Population Apoptotic (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	38.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	54.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	63.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	72.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	75.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	51.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	63.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	42.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	64.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	65.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	72.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	74.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	78.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	51.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	56.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	35.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	38.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	41.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	54.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	58.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	52.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	60.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	61.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	64.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	75.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	100.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	46.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	48.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	71.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	72.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	75.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	93.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	94.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	96.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	35.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	38.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	42.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	82.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	92.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	94.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	99.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	108.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	112.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	114.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	118.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	131.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	137.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	138.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	152.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	154.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	156.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	157.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	161.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	181.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	306.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	320.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	372.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	375.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	490.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	498.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	512.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	535.0	None	10.6019/CHEMBL4689842
Homo sapiens	U-87 MG	IC50	6.632	nM	10.6019/CHEMBL1201861
Homo sapiens	U-87 MG	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Homo sapiens	U-937	Activity	nan	None	10.1016/j.bmcl.2016.03.021
Homo sapiens	U-937	IC50	15.0	nM	10.1016/j.bmc.2006.09.024
Homo sapiens	U-937	IC50	32.0	nM	10.1016/j.bmc.2006.09.024
Homo sapiens	U-937	IC50	300.0	nM	10.1021/jm900469e
Homo sapiens	U-937	IC50	680.0	nM	10.1016/j.bmc.2006.09.024
Homo sapiens	U-937	IC50	1810.0	nM	10.1016/j.bmc.2023.117234
Homo sapiens	U-937	IC50	1980.0	nM	10.1016/j.ejmech.2012.01.014
Homo sapiens	U-937	IC50	nan	None	10.1016/j.bmc.2017.04.030
Homo sapiens	U-937	Inhibition	7.1	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	46.0	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	61.9	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	75.0	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	75.8	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	78.5	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	90.6	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	94.6	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	95.3	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	98.0	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	U-937	Inhibition	98.2	%	10.1016/j.bmcl.2005.12.032
Homo sapiens	UACC-257	GI50	54.33	nM	None
Homo sapiens	UACC-257	IC50	115.96	nM	10.6019/CHEMBL1201861
Homo sapiens	UACC-62	GI50	10.0	nM	10.1016/j.bmc.2009.08.066
Homo sapiens	UACC-62	GI50	10.0	nM	10.1016/j.bmc.2010.06.040
Homo sapiens	UACC-62	GI50	10.0	nM	10.1016/j.bmcl.2006.01.008
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/acs.jmedchem.6b01565
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/acs.jmedchem.6b01870
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm000029d
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm040025z
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm060046o
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm0613119
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm070307+
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm070361q
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm101338z
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm200719v
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm201512x
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm401471v
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm800259e
Homo sapiens	UACC-62	GI50	10.0	nM	10.1021/jm901649x
Homo sapiens	UACC-62	GI50	10.64	nM	None
Homo sapiens	UACC-62	IC50	31.03	nM	10.6019/CHEMBL1201861
Homo sapiens	UACC-893	IC50	383.65	nM	10.6019/CHEMBL1201861
Homo sapiens	UMC-11	IC50	2511.11	nM	10.6019/CHEMBL1201861
Homo sapiens	UMUC3	IC50	3.093	nM	10.6019/CHEMBL1201861
Homo sapiens	UO-31	GI50	30.27	nM	None
Homo sapiens	UO-31	IC50	34.07	nM	10.6019/CHEMBL1201861
Homo sapiens	VA-ES-BJ	IC50	3.469	nM	10.6019/CHEMBL1201861
Homo sapiens	Vascular endothelial growth factor receptor 1	IC50	nan	None	None
Homo sapiens	Vascular endothelial growth factor receptor 1	Ki	nan	None	None
Homo sapiens	Vasoactive intestinal polypeptide receptor 1	IC50	nan	None	None
Homo sapiens	Vasoactive intestinal polypeptide receptor 1	Ki	nan	None	None
Homo sapiens	Vasopressin V1a receptor	IC50	nan	None	None
Homo sapiens	Vasopressin V1a receptor	Ki	nan	None	None
Homo sapiens	VM-CUB-1	IC50	2.21	nM	10.6019/CHEMBL1201861
Homo sapiens	VMRC-RCZ	IC50	47.35	nM	10.6019/CHEMBL1201861
Homo sapiens	WI-38	IC50	0.03	ug.mL-1	10.1021/np400908u
Homo sapiens	WI-38	IC50	0.4	ug.mL-1	10.1016/j.ejmech.2013.06.004
Homo sapiens	WI-38	IC50	30.0	nM	10.1021/acs.jnatprod.6b01019
Homo sapiens	WI-38	IC50	8370.0	nM	10.1016/j.ejmech.2019.01.004
Homo sapiens	WiDr	ED50	0.07	ug ml-1	10.1021/np078016r
Homo sapiens	WiDr	GI50	1700.0	nM	10.1016/j.bmc.2009.07.053
Homo sapiens	WiDr	GI50	1800.0	nM	10.1016/j.ejmech.2013.06.013
Homo sapiens	WiDr	IC50	0.07	ug.mL-1	10.1021/np800126f
Homo sapiens	WiDr	IC50	17.0	nM	10.1021/jm0004751
Homo sapiens	WiDr	ID50	3.2	ng ml-1	10.1016/s0960-894x(02)00388-8
Homo sapiens	WIL2-NS	CC50	5.0	nM	10.1016/j.bmc.2011.10.009
Homo sapiens	WIL2-NS	CC50	5.0	nM	10.1016/j.ejmech.2012.07.020
Homo sapiens	WIL2-NS	IC50	5.0	nM	10.1016/j.ejmech.2006.11.013
Homo sapiens	WM-115	IC50	102.32	nM	10.6019/CHEMBL1201861
Homo sapiens	WM 266-4	GI	nan	None	10.1016/j.ejmech.2017.06.066
Homo sapiens	XF498	GI50	48.31	nM	None
Homo sapiens	YAPC	IC50	29.6	nM	10.6019/CHEMBL1201861
Homo sapiens	YH-13	IC50	11.65	nM	10.6019/CHEMBL1201861
Homo sapiens	YKG-1	IC50	5.453	nM	10.6019/CHEMBL1201861
Homo sapiens	ZR-75-1	IC50	10.0	nM	10.1016/j.ejmech.2012.10.013
Homo sapiens	ZR-75-30	IC50	240.0	nM	10.1016/j.bmcl.2017.03.039
Homo sapiens	ZR-75-30	IC50	261.0	nM	10.6019/CHEMBL1201861
Human immunodeficiency virus 1	Human immunodeficiency virus type 1 integrase	IC50	100000.0	nM	10.1021/jm9707232
Human immunodeficiency virus 1	Human immunodeficiency virus type 1 reverse transcriptase	IC50	200.0	ug.mL-1	10.1021/np50073a012
Klebsiella pneumoniae	Klebsiella pneumoniae	Inhibition	5.61	%	10.6019/CHEMBL4296183
Leishmania donovani	Leishmania donovani	EC50	nan	None	10.1021/np2004825
Leishmania donovani donovani	DNA topoisomerase I	Inhibition	39.0	%	10.1021/jm0610604
Leishmania donovani donovani	DNA topoisomerase I	Inhibition	55.0	%	10.1021/jm0610604
Leishmania donovani donovani	DNA topoisomerase I	Inhibition	65.0	%	10.1021/jm0610604
Leishmania infantum	Leishmania infantum	IC50	1120.0	nM	10.1021/acs.jmedchem.1c01491
Leishmania infantum	Leishmania infantum	IC50	34400.0	nM	10.1128/aac.00587-08
Leishmania infantum	Leishmania infantum	IC50	nan	None	10.1128/aac.00587-08
Leishmania major	DNA topoisomerase type IB small subunit	EC50	670.0	nM	10.1016/j.bmcl.2012.08.019
Leishmania major	DNA topoisomerase type IB small subunit	Inhibition	nan	%	10.1016/j.bmcl.2012.08.019
Leishmania mexicana mexicana	Leishmania mexicana mexicana	IC50	nan	None	10.1016/j.ejmech.2013.06.004
Mus musculus	4T1	IC50	170.0	nM	10.1021/acs.jmedchem.1c01411
Mus musculus	B16-F10	Inhibition	-1.9	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	7.5	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	16.2	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	33.4	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	39.1	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	47.8	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	60.6	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	76.9	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	83.2	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	93.5	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	94.7	%	10.1016/j.bmcl.2005.12.032
Mus musculus	B16-F10	Inhibition	98.1	%	10.1016/j.bmcl.2005.12.032
Mus musculus	CT26	IC50	34.0	nM	10.1021/jm051247f
Mus musculus	CT26.WT	IC50	430.0	nM	10.1021/acs.jmedchem.2c00635
Mus musculus	DNA topoisomerase I	IC50	12000.0	nM	10.1021/np0004606
Mus musculus	DNA topoisomerase I	IC50	40000.0	nM	10.1021/jm0004751
Mus musculus	DNA topoisomerase I	MIC	86.0	nM	10.1021/jm980702n
Mus musculus	H22	IC50	540.0	nM	10.1021/acs.jmedchem.1c01411
Mus musculus	L1210	Active dose	2.0	mg kg-1	10.1021/jm00158a044
Mus musculus	L1210	Cells arrested	81.0	%	10.1016/s0960-894x(03)00534-1
Mus musculus	L1210	Concentration	0.05	uM	10.1016/s0960-894x(02)00472-9
Mus musculus	L1210	ED50	2.8	10'-6umol/ml	10.1021/jm00189a018
Mus musculus	L1210	IC50	14.0	nM	10.1021/jm00123a038
Mus musculus	L1210	IC50	15.0	nM	10.1021/jm00075a025
Mus musculus	L1210	IC50	23.0	nM	10.1021/jm00105a017
Mus musculus	L1210	IC50	30.0	nM	10.1016/j.ejmech.2013.01.058
Mus musculus	L1210	IC50	30.0	nM	10.1016/s0960-894x(02)00472-9
Mus musculus	L1210	IC50	60.0	nM	10.1016/j.bmcl.2004.01.097
Mus musculus	L1210	IC50	126.0	nM	10.1016/S0960-894X(97)00398-3
Mus musculus	L1210	IC50	180.0	nM	10.1016/0960-894X(96)00131-X
Mus musculus	L1210	IC50	180.0	nM	10.1016/0960-894X(96)00132-1
Mus musculus	L1210	IC50	330.0	nM	10.1016/s0960-894x(03)00534-1
Mus musculus	L1210	IC50	510.0	nM	10.1021/jm500631u
Mus musculus	L1210	KE	4.8	None	10.1021/jm00070a013
Mus musculus	L1210	Radiation equivalent	240.0	None	10.1021/jm00123a038
Mus musculus	L1210	Radiation equivalent	342.0	None	10.1021/jm00123a038
Mus musculus	L1210	T/C	85.0	%	10.1021/jm00189a018
Mus musculus	L1210	T/C	114.0	%	10.1021/jm00189a018
Mus musculus	L1210	T/C	131.0	%	10.1021/jm00189a018
Mus musculus	L1210	T/C	164.0	%	10.1021/jm00158a044
Mus musculus	L1210	T/C	168.0	%	10.1021/jm00189a018
Mus musculus	L1210	T/C x100	200.0	mg kg-1	10.1021/jm00165a014
Mus musculus	L1210	TD50	0.01	ug ml-1	10.1016/0960-894X(95)00538-5
Mus musculus	L1210	Toxic dose	16.0	mg kg-1	10.1021/jm00158a044
Mus musculus	L1210	Treated cells	80.0	%	10.1016/s0960-894x(02)00472-9
Mus musculus	L1210/Adr	TD50	0.045	ug ml-1	10.1016/0960-894X(95)00538-5
Mus musculus	Lewis lung carcinoma cell line	IC50	33.0	nM	10.1021/jm010041l
Mus musculus	Lewis lung carcinoma cell line	IC50	33.0	nM	10.1021/jm020420u
Mus musculus	Liver	T1/2	1.75	hr	10.1016/j.bmc.2015.12.020
Mus musculus	MEF	IC50	5.87	ug.mL-1	10.1016/j.ejmech.2015.03.033
Mus musculus	Mus musculus	Activity	11.3	g	10.1016/j.bmcl.2014.10.048
Mus musculus	Mus musculus	Activity	nan	None	10.1016/j.bmcl.2014.10.048
Mus musculus	Mus musculus	CC50	620.0	nM	10.1016/j.ejmech.2016.09.017
Mus musculus	Mus musculus	Cures	1.0	None	10.1021/jm00070a013
Mus musculus	Mus musculus	ED50	0.02	ug ml-1	10.1021/jm00165a014
Mus musculus	Mus musculus	ED50	0.08	ug ml-1	10.1021/jm00165a014
Mus musculus	Mus musculus	Highest active dose	12.0	mg kg-1	10.1021/jm00070a013
Mus musculus	Mus musculus	ILS	118.0	%	10.1021/jm00105a017
Mus musculus	Mus musculus	ILS	193.0	%	10.1021/jm9600555
Mus musculus	Mus musculus	Inhibition	4.9	%	10.1016/s0960-894x(02)00926-5
Mus musculus	Mus musculus	Lactone	18.0	%	10.1021/jm9607562
Mus musculus	Mus musculus	Lactone	20.0	%	10.1021/jm9902279
Mus musculus	Mus musculus	Lactone	35.0	%	10.1021/jm9607562
Mus musculus	Mus musculus	Lactone	42.0	%	10.1021/jm9607562
Mus musculus	Mus musculus	Lactone	100.0	%	10.1021/jm9607562
Mus musculus	Mus musculus	LD50	56.2	mg.kg-1	10.1021/jm5003588
Mus musculus	Mus musculus	Log kill	0.7	None	10.1021/jm0005149
Mus musculus	Mus musculus	Log kill	1.2	None	10.1021/jm0005149
Mus musculus	Mus musculus	Log kill	2.8	None	10.1021/jm0005149
Mus musculus	Mus musculus	Mean time to death	38.7	day	10.1021/jm9600555
Mus musculus	Mus musculus	MTD	12.0	mg kg-1	10.1016/s0960-894x(02)00153-1
Mus musculus	Mus musculus	MTD	20.0	(mg of CPT) kg-1	10.1021/jm020022r
Mus musculus	Mus musculus	MTD	22.0	uM kg-1	10.1021/jm00105a017
Mus musculus	Mus musculus	NA	nan	None	10.1021/jm0005149
Mus musculus	Mus musculus	T/C	2.93	None	10.1021/jm9600555
Mus musculus	Mus musculus	T/C	129.0	None	10.1021/jm00395a024
Mus musculus	Mus musculus	T/C	147.0	None	10.1021/jm00395a024
Mus musculus	Mus musculus	T/C	183.0	%	10.1016/s0960-894x(02)00153-1
Mus musculus	Mus musculus	T/C	185.0	None	10.1021/jm00395a024
Mus musculus	Mus musculus	T/C	197.0	%	10.1021/jm00179a016
Mus musculus	Mus musculus	T/C	250.0	%	10.1021/jm00070a013
Mus musculus	Mus musculus	T/C	250.0	None	10.1021/jm00395a024
Mus musculus	Mus musculus	TGD	17.0	day	10.1021/jm020022r
Mus musculus	Mus musculus	Toxic dose	10.0	mg kg-1	10.1021/jm00070a013
Mus musculus	Nitric oxide synthase, inducible	IC50	nan	None	None
Mus musculus	Nitric oxide synthase, inducible	Ki	nan	None	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	56.2	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	79.4	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	316.2	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	398.1	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	501.2	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	631.0	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	1122.0	nM	None
Mus musculus	Nuclear receptor ROR-gamma	Potency	3548.1	nM	None
Mus musculus	P338	T/C	197.0	%	10.1021/jm00161a035
Mus musculus	P388	DOSE	4.0	mg.kg-1	10.1021/jm00179a016
Mus musculus	P388	DOSE	8.0	mg.kg-1	10.1021/jm00179a016
Mus musculus	P388	Dose range	8.0	mg kg-1	10.1021/jm00179a016
Mus musculus	P388	ED50	8.6	10'-6umol/ml	10.1021/jm00189a018
Mus musculus	P388	GI50	26.67	nM	None
Mus musculus	P388	IC50	0.004	nM	10.1016/j.bmcl.2008.05.005
Mus musculus	P388	IC50	0.00474	ug.mL-1	10.1021/jm00045a007
Mus musculus	P388	IC50	0.00474	ug.mL-1	10.1021/jm970765q
Mus musculus	P388	IC50	0.005	ug.mL-1	10.1016/S0960-894X(97)00071-1
Mus musculus	P388	IC50	4.0	nM	10.1016/j.bmc.2008.08.018
Mus musculus	P388	IC50	4.0	nM	10.1016/j.bmc.2009.02.023
Mus musculus	P388	IC50	4.0	nM	10.1016/j.ejmech.2009.02.004
Mus musculus	P388	IC50	7.0	nM	10.1016/s0960-894x(02)00926-5
Mus musculus	P388	IC50	9.0	nM	10.1016/j.bmc.2008.06.046
Mus musculus	P388	IC50	10.0	nM	10.1016/j.bmcl.2004.08.070
Mus musculus	P388	IC50	13.0	nM	10.1021/jm010041l
Mus musculus	P388	IC50	13.0	nM	10.1021/jm020420u
Mus musculus	P388	IC50	14.0	nM	10.1016/j.bmc.2008.09.002
Mus musculus	P388	IC50	14.0	nM	10.1016/j.ejmech.2008.09.048
Mus musculus	P388	IC50	32.0	nM	10.1021/jm980702n
Mus musculus	P388	IC50	32.1	nM	10.1016/j.bmc.2007.06.047
Mus musculus	P388	IC50	10000.0	nM	10.1016/j.bmc.2008.06.046
Mus musculus	P388	IC50	10000.0	nM	10.1016/j.bmc.2008.08.018
Mus musculus	P388	IC50	10000.0	nM	10.1016/j.bmc.2009.02.023
Mus musculus	P388	IC50	nan	None	10.1021/np960336f
Mus musculus	P388	T/C	81.0	%	10.1021/jm00189a018
Mus musculus	P388	T/C	137.0	%	10.1021/jm00189a018
Mus musculus	P388	T/C	147.0	%	10.1021/jm00189a018
Mus musculus	P388	T/C	175.0	%	10.1021/np50005a006
Mus musculus	P388	T/C	181.0	%	10.1021/np50005a006
Mus musculus	P388	T/C	204.0	%	10.1021/jm00189a018
Mus musculus	P388	T/C x100	199.0	mg kg-1	10.1021/jm00165a014
Mus musculus	P388/ADR	GI50	25.35	nM	None
Mus musculus	P388CPT5	IC50	2800.0	nM	10.1021/jm980702n
Mus musculus	Plasma	Activity	5.3	%	10.1016/j.ejmech.2008.01.008
Mus musculus	Plasma	Activity	10.9	%	10.1016/j.ejmech.2008.01.008
Mus musculus	Plasma	Activity	24.5	%	10.1016/j.ejmech.2008.01.008
Mus musculus	Plasma	Activity	40.5	%	10.1016/j.ejmech.2008.01.008
Mus musculus	Plasma	Activity	55.1	%	10.1016/j.ejmech.2008.01.008
Mus musculus	Renca	IC50	304.0	nM	10.1021/jm051247f
Oryctolagus cuniculus	Angiotensin-converting enzyme	IC50	nan	None	None
Oryctolagus cuniculus	Angiotensin-converting enzyme	Ki	nan	None	None
Oryctolagus cuniculus	Arachidonate 15-lipoxygenase	IC50	nan	None	None
Oryctolagus cuniculus	Arachidonate 15-lipoxygenase	Ki	nan	None	None
Oryza sativa Japonica Group	Os06g0676700 protein	Potency	15848.9	nM	None
Plasmodium falciparum	Plasmodium falciparum	IC50	0.56	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	0.83	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	0.89	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	1.12	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	1.32	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	1.41	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	501.19	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	794.33	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	1000.0	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	1258.93	nM	10.1038/nchembio.215
Plasmodium falciparum	Plasmodium falciparum	IC50	nan	None	10.1016/j.bmcl.2016.12.043
Plasmodium falciparum	Plasmodium falciparum	IC50	nan	None	10.1016/j.ejmech.2013.06.004
Plasmodium falciparum	Plasmodium falciparum	IC50	nan	None	10.1016/j.ejmech.2015.05.044
Plasmodium falciparum	Plasmodium falciparum	IC50	nan	None	10.1016/j.ejmech.2021.113330
Plasmodium falciparum	Plasmodium falciparum	IC50	nan	None	10.1021/acs.jnatprod.6b01019
Plasmodium falciparum	Plasmodium falciparum	IC50	nan	None	10.1021/np2004825
Plasmodium falciparum	Plasmodium falciparum	Potency	1168.9	nM	None
Plasmodium falciparum	Plasmodium falciparum	Potency	1471.6	nM	None
Plasmodium falciparum	Plasmodium falciparum	Potency	2332.3	nM	None
Pneumocystis carinii	Pneumocystis carinii	IC50	nan	None	10.1021/np100201p
Providencia stuartii	Type-2 restriction enzyme PstI	IC50	300000.0	nM	10.1021/np0004606
Pseudomonas aeruginosa	Pseudomonas aeruginosa	Inhibition	11.38	%	10.6019/CHEMBL4296183
Rattus norvegicus	Aldose reductase	IC50	nan	None	None
Rattus norvegicus	Aldose reductase	Ki	nan	None	None
Rattus norvegicus	Alpha-1a adrenergic receptor	IC50	nan	None	None
Rattus norvegicus	Alpha-1a adrenergic receptor	Ki	nan	None	None
Rattus norvegicus	Alpha-1b adrenergic receptor	IC50	nan	None	None
Rattus norvegicus	Alpha-1b adrenergic receptor	Ki	nan	None	None
Rattus norvegicus	Androgen Receptor	IC50	nan	None	None
Rattus norvegicus	Androgen Receptor	Ki	nan	None	None
Rattus norvegicus	C6	IC50	1850.0	nM	10.1016/j.ejmech.2022.114376
Rattus norvegicus	Glycine receptor	IC50	nan	None	None
Rattus norvegicus	Glycine receptor	Ki	nan	None	None
Rattus norvegicus	Hippocampus	Activity	51.6	%	10.1016/j.bmc.2008.07.045
Rattus norvegicus	Inositol monophosphatase 1	Potency	316.2	nM	None
Rattus norvegicus	Insulin receptor	IC50	nan	None	None
Rattus norvegicus	Insulin receptor	Ki	nan	None	None
Rattus norvegicus	Nitric-oxide synthase, brain	IC50	nan	None	None
Rattus norvegicus	Nitric-oxide synthase, brain	Ki	nan	None	None
Rattus norvegicus	PC-12	Activity	nan	None	10.1021/acs.jmedchem.0c00894
Rattus norvegicus	Rattus norvegicus	ALB	40300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	41200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	42000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	42200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALB	43000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	247.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	352.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	392.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	406.83	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	408.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALP	430.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	37.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	42.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	43.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	51.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	55.5	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	ALT	60.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	70.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	79.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	81.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	101.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	101.5	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	AST	104.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BASO	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BASOLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	1.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	2.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BILI	2.2	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	126.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	130.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	135.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	146.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	161.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	BUN	170.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	100.5	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	101.33	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	102.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	102.17	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHLORIDE	103.33	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	560.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	636.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	643.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	648.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	736.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CHOL	750.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	241.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	242.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	318.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	674.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	727.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CK	732.67	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	22330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	29330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	30330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	30670000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	33000000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CO2	33330000.0	nM	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	1.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	1.6	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	1.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	CREAT	2.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	0.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	17.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	21.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	41.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOS	45.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	EOSLE	0.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1383.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1533.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1570.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1840.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	1868.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	GLUC	2016.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	31.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	32.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	34.62	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	34.8	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	35.9	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HCT	37.42	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	121300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	132000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	136300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	138000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	140300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	HGB	144000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	IC50	nan	nM	10.1016/s0960-894x(03)00016-7
Rattus norvegicus	Rattus norvegicus	LDH	136.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	147.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	188.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	388.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	442.5	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LDH	581.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	10.33	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	10.83	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LIPASE	11.0	U.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	7405.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	9985.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	10193.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	11849.17	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	11856.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYM	12074.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	89.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	91.83	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	92.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	93.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	94.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	LYMLE	95.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	22.77	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.32	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	24.57	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	25.13	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	25.68	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCH	25.93	pg	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	383300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	385000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	390700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	392300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	399000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCHC	408700.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	59.3	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	62.87	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	63.08	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	63.53	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	63.97	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MCV	64.37	fL	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	46.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	69.83	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	83.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	102.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	131.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONO	165.83	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	0.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	0.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	0.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	1.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	1.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	MONOLE	1.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	3.0	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	5.67	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	6.17	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	6.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	6.5	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTLE	9.33	%	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	225.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	602.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	702.17	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	730.67	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	834.33	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	NEUTSG	1233.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	108.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	110.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	116.7	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	119.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	124.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PHOS	126.8	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	732670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1170500.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1202830.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1215000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1247670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PLAT	1318330.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.31	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.51	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.67	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	5.76	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.08	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	POTASSIUM	6.3	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	59300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60200.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60300.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	60800.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	PROT	61000.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5090000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5350000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5390000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5450000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5710000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBC	5930000.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	RBCNUC	0.0	/100WBC	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	141.3	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	142.1	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	142.55	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	142.73	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	144.0	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	SODIUM	145.33	mEq.L-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	T1/2	nan	hr	10.1016/s0960-894x(03)00016-7
Rattus norvegicus	Rattus norvegicus	Tissue Severity Score	nan	None	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	13.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	15.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	16.3	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	18.0	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	URATE	18.5	ug.mL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	7730.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	10630.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	11080.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	12670.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	13030.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Rattus norvegicus	WBC	13270.0	cells.uL-1	10.6019/CHEMBL3885881
Rattus norvegicus	Serotonin 1a (5-HT1a) receptor	IC50	nan	None	None
Rattus norvegicus	Serotonin 1a (5-HT1a) receptor	Ki	nan	None	None
Rattus norvegicus	Serotonin 1b (5-HT1b) receptor	IC50	nan	None	None
Rattus norvegicus	Serotonin 1b (5-HT1b) receptor	Ki	nan	None	None
Rattus norvegicus	Small intestine	Ka	3.02	/hr	10.1016/j.ejmech.2014.06.050
Rattus norvegicus	Small intestine	Peff	7.48	10'-5cm/s	10.1016/j.ejmech.2014.06.050
Rattus norvegicus	Thioredoxin reductase 1, cytoplasmic	Potency	2818.4	nM	None
Rattus norvegicus	Thioredoxin reductase 1, cytoplasmic	Potency	5323.3	nM	None
Rattus norvegicus	Thioredoxin reductase 1, cytoplasmic	Potency	13371.4	nM	None
Rattus norvegicus	Thioredoxin reductase 1, cytoplasmic	Potency	22387.2	nM	None
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	0.6	ug ml-1	10.1021/np010123c
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	0.6	ug ml-1	10.1021/np50103a009
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	8.7	ug ml-1	10.1021/np50103a009
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	20.0	ug ml-1	10.1021/np010123c
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	20.0	ug ml-1	10.1021/np50103a009
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	110.0	ug ml-1	10.1021/np010123c
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Activity	nan	None	10.1021/np50103a009
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	0.6	ug ml-1	10.1021/np50089a014
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	0.6	ug ml-1	10.1021/np50099a008
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	0.6	ug ml-1	10.1021/np50106a013
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	0.6	ug ml-1	10.1021/np50125a006
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	0.6	ug ml-1	10.1021/np9701687
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	0.9	ug ml-1	10.1021/np960125a
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	5.0	ug ml-1	10.1021/np0303963
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	8.7	ug ml-1	10.1021/np50089a014
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	8.7	ug ml-1	10.1021/np50106a013
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	8.7	ug ml-1	10.1021/np50125a006
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	12.0	ug ml-1	10.1021/np020186a
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	75.0	ug ml-1	10.1021/np020186a
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	100.0	ug ml-1	10.1021/np960125a
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	110.0	ug ml-1	10.1021/np50099a008
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	110.0	ug ml-1	10.1021/np50106a013
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	110.0	ug ml-1	10.1021/np9701687
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC12	200.0	ug ml-1	10.1021/np0303963
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC50	0.014	ug.mL-1	10.1021/np000058r
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC50	0.06	ug.mL-1	10.1021/np000058r
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC50	0.16	ug.mL-1	10.1021/np000058r
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC50	0.18	ug.mL-1	10.1021/np000058r
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC50	100.0	ug.mL-1	10.1021/np000058r
Saccharomyces cerevisiae	Saccharomyces cerevisiae	IC50	200000.0	nM	10.1073/pnas.0709443104
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Inhibition	10.0	%	10.1016/j.bmcl.2004.02.069
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Inhibition	18.0	%	10.1016/j.bmcl.2004.02.069
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Inhibition	19.0	%	10.1016/j.bmcl.2004.02.069
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Inhibition	40.0	%	10.1016/j.bmcl.2004.02.069
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Inhibition	68.0	%	10.1016/j.bmcl.2004.02.069
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Inhibition	78.0	%	10.1016/j.bmcl.2004.02.069
Saccharomyces cerevisiae	Saccharomyces cerevisiae	Potency	12995.3	nM	None
Schistosoma mansoni	Schistosoma mansoni	In vitro activity	nan	None	10.6019/CHEMBL5096127
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	-49.62	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	106.22	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	19952.62	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	20000.0	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	-0.11	%	10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	1.0	%	10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	81.85	%	10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition index	-0.1388	None	10.1101/2020.04.03.023846
Staphylococcus aureus	Staphylococcus aureus	Inhibition	9.46	%	10.6019/CHEMBL4296183
Streptomyces caespitosus	Type-2 restriction enzyme ScaI	IC50	300000.0	nM	10.1021/np0004606
Sus scrofa	Deoxyribonuclease-2-alpha	IC50	300000.0	nM	10.1021/np0004606
Trypanosoma brucei brucei	Trypanosoma brucei brucei	EC50	nan	None	10.1021/np2004825
Trypanosoma brucei brucei	Trypanosoma brucei brucei	IC50	nan	None	10.1016/j.ejmech.2013.06.004
Trypanosoma brucei brucei	Trypanosoma brucei brucei	IC50	nan	None	10.1016/j.ejmech.2015.05.044
Trypanosoma brucei brucei	Trypanosoma brucei brucei	Inhibition	27.0	%	10.1128/aac.00650-07
Trypanosoma cruzi	Cruzipain	Potency	3981.1	nM	None
None	ADMET	Activity	10.0	%	10.1021/acs.jmedchem.1c01362
None	ADMET	Activity	33.78	%	10.1016/j.ejmech.2011.07.036
None	ADMET	Activity	34.6	%	10.1016/j.bmc.2016.04.036
None	ADMET	Activity	nan	None	10.1016/j.ejmech.2021.113916
None	ADMET	Activity	nan	None	10.1021/acs.jmedchem.1c01362
None	ADMET	Activity	nan	None	10.1021/acs.jmedchem.2c00968
None	ADMET	CC50	300.0	nM	10.1016/j.bmc.2011.10.009
None	ADMET	CC50	300.0	nM	10.1016/j.ejmech.2012.07.020
None	ADMET	Drug uptake	nan	None	10.1021/acs.jmedchem.1c01362
None	ADMET	Fold increase	3.5	None	10.1021/jm9707232
None	ADMET	GI50	40.0	nM	10.1021/jm0613119
None	ADMET	GI50	nan	None	10.1016/j.ejmech.2010.11.013
None	ADMET	IC50	0.016	ug.mL-1	10.1021/np50125a006
None	ADMET	IC50	11.71	ug.mL-1	10.1016/j.ejmech.2015.03.033
None	ADMET	IC50	230.0	nM	10.1016/j.ejmech.2013.07.016
None	ADMET	IC50	230.0	nM	10.1016/j.ejmech.2015.05.044
None	ADMET	IC50	270.0	nM	10.1016/j.ejmech.2014.05.047
None	ADMET	IC50	459.3	nM	10.1021/np100886y
None	ADMET	IC50	620.0	nM	10.1016/j.bmcl.2012.08.019
None	ADMET	IC50	970.0	nM	10.1016/j.bmc.2015.08.018
None	ADMET	IC50	3200.0	nM	10.1016/j.ejmech.2015.11.037
None	ADMET	IC50	4470.0	nM	10.1016/j.ejmech.2013.07.016
None	ADMET	IC50	4960.0	nM	10.1016/j.bmc.2015.11.007
None	ADMET	IC50	18300.0	nM	10.1016/j.bmcl.2011.12.095
None	ADMET	IC50	nan	None	10.1021/np100201p
None	ADMET	Kd	94.0	nM	10.1016/j.bmcl.2005.07.017
None	ADMET	Kd	112.0	nM	10.1016/j.bmcl.2005.07.017
None	ADMET	K DMPC	100.0	M-1	10.1021/jm9902279
None	ADMET	KDMPC	100.0	M-1	10.1021/jm000144o
None	ADMET	K DMPG	100.0	M-1	10.1021/jm9902279
None	ADMET	Lactone	0.0	%	10.1021/jm9607562
None	ADMET	Lactone	0.5	%	10.1021/jm000144o
None	ADMET	Lactone	0.5	%	10.1021/jm9607562
None	ADMET	Lactone	12.0	%	10.1021/jm9607562
None	ADMET	Lactone	17.0	%	10.1021/jm000144o
None	ADMET	Lactone	34.6	%	10.1021/jm000144o
None	ADMET	Lactone	100.0	%	10.1021/jm9607562
None	ADMET	LC50	nan	None	10.1016/j.ejmech.2010.11.013
None	ADMET	Peff	7.88	ucm/s	10.1016/j.ejmech.2014.06.050
None	ADMET	permeability	nan	None	10.1016/j.ejmech.2014.06.050
None	ADMET	Ratio IC50	0.01	None	10.1016/j.ejmech.2021.113330
None	ADMET	Ratio IC50	2.5	None	10.1021/acs.jmedchem.2c00204
None	ADMET	Selectivity Index	5.2	None	10.1021/acs.jmedchem.1c01411
None	ADMET	Stability	15.7	%	10.1016/j.ejmech.2020.112551
None	ADMET	Stability	15.7	%	10.1021/acs.jmedchem.8b01938
None	ADMET	Stability	20.0	%	10.1016/j.ejmech.2012.05.002
None	ADMET	T1/2	0.07833	hr	10.1016/j.bmcl.2004.08.010
None	ADMET	T1/2	0.1983	hr	10.1021/jm000144o
None	ADMET	T1/2	0.2083	hr	10.1021/jm00027a005
None	ADMET	T1/2	0.3967	hr	10.1021/jm000144o
None	ADMET	T1/2	0.3967	hr	10.1021/jm00027a005
None	ADMET	T1/2	0.5133	hr	10.1021/jm000144o
None	ADMET	T1/2	1.183	hr	10.1021/acs.jmedchem.9b00726
None	ADMET	T1/2	nan	hr	10.1016/s0960-894x(03)00016-7
None	ADMET	T free	4.2	ns	10.1021/jm00027a005
None	ADMET	T free	4.3	ns	10.1021/jm00027a005
None	ADMET	TGI	nan	None	10.1016/j.ejmech.2010.11.013
None	ADMET	Therapeutic index	8.0	None	10.1021/jm00179a016
None	Erythrocyte	Activity	nan	None	10.1021/acs.jnatprod.6b01019
None	Erythrocyte	EC50	429.9	ug.mL-1	10.1007/s00044-010-9381-7
None	Hepatotoxicity	Hepatotoxicity	nan	None	10.1021/tx900326k
None	KB VCR R	IC50	0.03	ug.mL-1	10.1016/S0960-894X(01)80158-X
None	KB VCR R	IC50	9.0	nM	10.1016/j.bmcl.2003.08.012
None	Molecular identity unknown	Activity	4.4	%	10.1016/j.ejmech.2016.07.042
None	Molecular identity unknown	Activity	11.32	%	10.1016/j.ejmech.2016.06.054
None	Molecular identity unknown	Activity	16.3	%	10.1016/j.ejmech.2016.07.042
None	Molecular identity unknown	Activity	25.8	%	10.1016/j.ejmech.2016.07.042
None	Molecular identity unknown	Activity	33.16	%	10.1016/j.ejmech.2016.06.054
None	Molecular identity unknown	Activity	48.15	%	10.1016/j.ejmech.2016.06.054
None	Molecular identity unknown	Activity	54.6	%	10.1016/j.ejmech.2016.07.042
None	Molecular identity unknown	Activity	60.9	%	10.1039/C5MD00289C
None	Molecular identity unknown	Activity	nan	None	10.1016/j.bmcl.2016.03.021
None	NCI-H928	IC50	7.8	nM	10.1021/jm990124q
None	NON-PROTEIN TARGET	Activity	12.8	%	10.1016/j.bmc.2016.04.036
None	NON-PROTEIN TARGET	Activity	23.4	%	10.1016/j.bmc.2016.04.036
None	NON-PROTEIN TARGET	Activity	nan	None	10.1016/j.bmc.2015.12.020
None	NON-PROTEIN TARGET	Activity	nan	None	10.1016/j.bmcl.2010.06.144
None	NON-PROTEIN TARGET	Activity	nan	None	10.1016/j.bmcl.2011.01.013
None	NON-PROTEIN TARGET	ED50	2.0	ug ml-1	10.1021/jm00179a016
None	NON-PROTEIN TARGET	ED50	2.8	10'-6umol/ml	10.1021/jm00189a018
None	NON-PROTEIN TARGET	ED50	15.0	nM	10.1016/j.bmcl.2007.02.051
None	NON-PROTEIN TARGET	ED50	230.0	nM	10.1021/np0304417
None	NON-PROTEIN TARGET	GI50	1.5	nM	10.1016/j.bmc.2007.10.012
None	NON-PROTEIN TARGET	GI50	2.0	nM	10.1016/j.ejmech.2016.08.045
None	NON-PROTEIN TARGET	GI50	2.1	nM	10.1016/j.ejmech.2016.08.045
None	NON-PROTEIN TARGET	GI50	5.4	nM	10.1016/j.ejmech.2016.08.045
None	NON-PROTEIN TARGET	GI50	10.0	nM	10.1021/acs.jmedchem.6b00003
None	NON-PROTEIN TARGET	GI50	10.0	nM	10.1021/jm040025z
None	NON-PROTEIN TARGET	GI50	10.0	nM	10.1021/jm050076b
None	NON-PROTEIN TARGET	GI50	10.0	nM	10.1021/jm500294a
None	NON-PROTEIN TARGET	GI50	10.0	nM	10.1021/jm900469e
None	NON-PROTEIN TARGET	GI50	20.0	nM	10.1016/j.bmc.2007.03.067
None	NON-PROTEIN TARGET	GI50	20.0	nM	10.1021/jm050076b
None	NON-PROTEIN TARGET	GI50	30.0	nM	10.1021/acs.jmedchem.6b00003
None	NON-PROTEIN TARGET	GI50	30.0	nM	10.1021/jm050076b
None	NON-PROTEIN TARGET	GI50	33.0	nM	10.1021/jm1009428
None	NON-PROTEIN TARGET	GI50	39.8	nM	10.1016/j.ejmech.2016.06.030
None	NON-PROTEIN TARGET	GI50	40.0	nM	10.1021/jm050076b
None	NON-PROTEIN TARGET	GI50	43.21	nM	10.1021/jm9005059
None	NON-PROTEIN TARGET	GI50	80.0	nM	10.1021/jm900469e
None	NON-PROTEIN TARGET	GI50	210.0	nM	10.1021/np9006734
None	NON-PROTEIN TARGET	GI50	220.0	nM	10.1016/j.bmc.2007.12.028
None	NON-PROTEIN TARGET	GI50	220.0	nM	10.1021/acs.jmedchem.6b00003
None	NON-PROTEIN TARGET	GI50	220.0	nM	10.1021/jm050076b
None	NON-PROTEIN TARGET	GI50	220.0	nM	10.1021/jm1005447
None	NON-PROTEIN TARGET	GI50	220.0	nM	10.1021/jm500294a
None	NON-PROTEIN TARGET	GI50	1000.0	nM	10.1021/jm401471v
None	NON-PROTEIN TARGET	GI50	1030.0	nM	10.1021/jm1005447
None	NON-PROTEIN TARGET	IC50	0.004	nM	10.1016/j.bmcl.2008.05.005
None	NON-PROTEIN TARGET	IC50	0.08	ug.mL-1	10.1021/np800126f
None	NON-PROTEIN TARGET	IC50	0.15	nM	10.1016/j.ejmech.2014.09.056
None	NON-PROTEIN TARGET	IC50	1.4	nM	10.1016/j.ejmech.2016.07.046
None	NON-PROTEIN TARGET	IC50	3.0	nM	10.1021/acs.jmedchem.5b00910
None	NON-PROTEIN TARGET	IC50	3.0	nM	10.1021/acsmedchemlett.5b00441
None	NON-PROTEIN TARGET	IC50	4.0	nM	10.1016/j.bmc.2008.08.018
None	NON-PROTEIN TARGET	IC50	4.0	nM	10.1016/j.bmc.2009.02.023
None	NON-PROTEIN TARGET	IC50	4.0	nM	10.1016/j.ejmech.2009.02.004
None	NON-PROTEIN TARGET	IC50	4.0	nM	10.1016/j.ejmech.2014.09.056
None	NON-PROTEIN TARGET	IC50	5.0	nM	10.1016/j.bmc.2008.06.046
None	NON-PROTEIN TARGET	IC50	5.5	nM	10.1016/j.ejmech.2016.03.031
None	NON-PROTEIN TARGET	IC50	5.6	nM	10.1021/jm970044r
None	NON-PROTEIN TARGET	IC50	6.0	nM	10.1016/j.bmc.2008.09.002
None	NON-PROTEIN TARGET	IC50	6.8	nM	10.1016/j.bmc.2012.05.030
None	NON-PROTEIN TARGET	IC50	8.5	nM	10.1021/jm990124q
None	NON-PROTEIN TARGET	IC50	10.0	nM	10.1016/j.bmcl.2008.05.005
None	NON-PROTEIN TARGET	IC50	10.0	nM	10.1016/j.bmcl.2012.06.016
None	NON-PROTEIN TARGET	IC50	10.0	nM	10.1021/np400483c
None	NON-PROTEIN TARGET	IC50	15.0	nM	10.1016/j.bmc.2008.06.046
None	NON-PROTEIN TARGET	IC50	15.0	nM	10.1016/j.bmc.2008.08.018
None	NON-PROTEIN TARGET	IC50	15.0	nM	10.1021/np400483c
None	NON-PROTEIN TARGET	IC50	15.0	nM	10.1039/C4MD00133H
None	NON-PROTEIN TARGET	IC50	20.0	nM	10.1016/j.ejmech.2016.02.050
None	NON-PROTEIN TARGET	IC50	24.0	nM	10.1016/j.bmc.2012.05.030
None	NON-PROTEIN TARGET	IC50	24.0	nM	10.1016/j.bmcl.2007.08.062
None	NON-PROTEIN TARGET	IC50	25.0	nM	10.1016/j.bmc.2008.06.046
None	NON-PROTEIN TARGET	IC50	25.0	nM	10.1016/j.bmc.2008.08.018
None	NON-PROTEIN TARGET	IC50	26.0	nM	10.1016/j.bmc.2008.06.046
None	NON-PROTEIN TARGET	IC50	26.0	nM	10.1016/j.bmc.2008.08.018
None	NON-PROTEIN TARGET	IC50	28.7	nM	10.1021/np010420h
None	NON-PROTEIN TARGET	IC50	30.0	nM	10.1016/j.ejmech.2016.09.017
None	NON-PROTEIN TARGET	IC50	30.0	nM	10.1021/np100201p
None	NON-PROTEIN TARGET	IC50	30.0	nM	10.1021/np900827a
None	NON-PROTEIN TARGET	IC50	33.0	nM	10.1021/jm970044r
None	NON-PROTEIN TARGET	IC50	35.0	nM	10.1021/acsmedchemlett.5b00441
None	NON-PROTEIN TARGET	IC50	37.1	nM	10.1016/j.bmcl.2012.10.002
None	NON-PROTEIN TARGET	IC50	40.0	nM	10.1021/np400988a
None	NON-PROTEIN TARGET	IC50	52.0	nM	10.1021/jm101354u
None	NON-PROTEIN TARGET	IC50	57.0	nM	10.1021/jm101354u
None	NON-PROTEIN TARGET	IC50	60.0	nM	10.1021/jm900469e
None	NON-PROTEIN TARGET	IC50	70.0	nM	10.1016/j.ejmech.2015.01.024
None	NON-PROTEIN TARGET	IC50	70.0	nM	10.1016/j.ejmech.2016.03.031
None	NON-PROTEIN TARGET	IC50	80.0	nM	10.1016/j.ejmech.2016.07.046
None	NON-PROTEIN TARGET	IC50	100.0	nM	10.1016/j.bmc.2016.01.013
None	NON-PROTEIN TARGET	IC50	100.0	nM	10.1021/jm3001532
None	NON-PROTEIN TARGET	IC50	100.0	nM	10.1039/C4MD00306C
None	NON-PROTEIN TARGET	IC50	110.0	nM	10.1016/j.ejmech.2016.09.019
None	NON-PROTEIN TARGET	IC50	120.0	nM	10.1016/j.ejmech.2016.02.070
None	NON-PROTEIN TARGET	IC50	120.0	nM	10.1016/j.ejmech.2016.06.021
None	NON-PROTEIN TARGET	IC50	120.0	nM	10.1021/jm5003588
None	NON-PROTEIN TARGET	IC50	130.0	nM	10.1016/j.ejmech.2016.07.046
None	NON-PROTEIN TARGET	IC50	131.0	nM	10.1016/j.ejmech.2014.06.050
None	NON-PROTEIN TARGET	IC50	140.0	nM	10.1021/acs.jmedchem.5b00910
None	NON-PROTEIN TARGET	IC50	190.0	nM	10.1039/C4MD00344F
None	NON-PROTEIN TARGET	IC50	220.0	nM	10.1039/C4MD00133H
None	NON-PROTEIN TARGET	IC50	260.0	nM	10.1016/j.bmc.2014.11.010
None	NON-PROTEIN TARGET	IC50	260.0	nM	10.1021/np200706n
None	NON-PROTEIN TARGET	IC50	300.0	nM	10.1021/np400672g
None	NON-PROTEIN TARGET	IC50	310.0	nM	10.1016/j.ejmech.2016.09.019
None	NON-PROTEIN TARGET	IC50	330.0	nM	10.1021/jm0108092
None	NON-PROTEIN TARGET	IC50	350.0	nM	10.1016/j.ejmech.2016.09.004
None	NON-PROTEIN TARGET	IC50	380.0	nM	10.1016/j.ejmech.2016.09.004
None	NON-PROTEIN TARGET	IC50	400.0	nM	10.1016/j.ejmech.2016.09.019
None	NON-PROTEIN TARGET	IC50	423.0	nM	10.1016/j.bmc.2012.05.030
None	NON-PROTEIN TARGET	IC50	460.0	nM	10.1016/j.ejmech.2016.06.054
None	NON-PROTEIN TARGET	IC50	474.0	nM	10.1021/jm500631u
None	NON-PROTEIN TARGET	IC50	500.0	nM	10.1016/j.ejmech.2006.11.013
None	NON-PROTEIN TARGET	IC50	500.0	nM	10.1016/j.ejmech.2010.11.046
None	NON-PROTEIN TARGET	IC50	590.0	nM	10.1016/j.ejmech.2016.09.004
None	NON-PROTEIN TARGET	IC50	600.0	nM	10.1016/j.ejmech.2016.07.046
None	NON-PROTEIN TARGET	IC50	710.0	nM	10.1021/acs.jmedchem.5b00910
None	NON-PROTEIN TARGET	IC50	786.0	nM	10.1021/jm500631u
None	NON-PROTEIN TARGET	IC50	800.0	nM	10.1016/j.bmcl.2011.11.116
None	NON-PROTEIN TARGET	IC50	830.0	nM	10.1016/j.ejmech.2016.09.019
None	NON-PROTEIN TARGET	IC50	890.0	nM	10.1016/j.ejmech.2016.09.065
None	NON-PROTEIN TARGET	IC50	960.0	nM	10.1021/acs.jmedchem.5b00910
None	NON-PROTEIN TARGET	IC50	1000.0	nM	10.1016/j.bmc.2012.07.016
None	NON-PROTEIN TARGET	IC50	1000.0	nM	10.1016/j.bmc.2016.01.013
None	NON-PROTEIN TARGET	IC50	1000.0	nM	10.1039/C4MD00306C
None	NON-PROTEIN TARGET	IC50	1060.0	nM	10.1016/j.ejmech.2016.09.019
None	NON-PROTEIN TARGET	IC50	1120.0	nM	10.1016/j.ejmech.2016.09.017
None	NON-PROTEIN TARGET	IC50	1240.0	nM	10.1016/j.ejmech.2016.09.065
None	NON-PROTEIN TARGET	IC50	1270.0	nM	10.1016/j.ejmech.2016.06.054
None	NON-PROTEIN TARGET	IC50	1290.0	nM	10.1016/j.bmcl.2016.02.053
None	NON-PROTEIN TARGET	IC50	1410.0	nM	10.1016/j.ejmech.2016.06.054
None	NON-PROTEIN TARGET	IC50	1520.0	nM	10.1016/j.ejmech.2016.06.054
None	NON-PROTEIN TARGET	IC50	1700.0	nM	10.1021/jm900469e
None	NON-PROTEIN TARGET	IC50	1840.0	nM	10.1016/j.ejmech.2016.09.065
None	NON-PROTEIN TARGET	IC50	1980.0	nM	10.1016/j.ejmech.2014.07.058
None	NON-PROTEIN TARGET	IC50	2780.0	nM	10.1016/j.bmcl.2014.03.004
None	NON-PROTEIN TARGET	IC50	2820.0	nM	10.1016/j.ejmech.2016.02.050
None	NON-PROTEIN TARGET	IC50	3040.0	nM	10.1016/j.ejmech.2016.09.065
None	NON-PROTEIN TARGET	IC50	3280.0	nM	10.1016/j.bmcl.2008.05.103
None	NON-PROTEIN TARGET	IC50	3600.0	nM	10.1021/np400988a
None	NON-PROTEIN TARGET	IC50	4540.0	nM	10.1016/j.ejmech.2016.09.004
None	NON-PROTEIN TARGET	IC50	5385.0	nM	10.1021/jm049060w
None	NON-PROTEIN TARGET	IC50	5930.0	nM	10.1016/j.ejmech.2016.09.065
None	NON-PROTEIN TARGET	IC50	6300.0	nM	10.1021/np400988a
None	NON-PROTEIN TARGET	IC50	6700.0	nM	10.1016/j.ejmech.2016.09.065
None	NON-PROTEIN TARGET	IC50	7000.0	nM	10.1016/j.bmc.2016.03.017
None	NON-PROTEIN TARGET	IC50	7100.0	nM	10.1016/j.bmc.2016.03.017
None	NON-PROTEIN TARGET	IC50	9520.0	nM	10.1016/j.bmc.2016.09.034
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1016/j.bmc.2008.08.018
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1016/j.bmc.2008.09.002
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1016/j.bmc.2009.02.023
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1016/j.bmcl.2004.08.070
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1016/j.ejmech.2009.02.004
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1021/np400672g
None	NON-PROTEIN TARGET	IC50	10070.0	nM	10.1016/j.ejmech.2014.05.047
None	NON-PROTEIN TARGET	IC50	11360.0	nM	10.1016/j.bmc.2016.09.034
None	NON-PROTEIN TARGET	IC50	13700.0	nM	10.1016/j.ejmech.2016.09.019
None	NON-PROTEIN TARGET	IC50	15200.0	nM	10.1016/j.bmcl.2011.12.095
None	NON-PROTEIN TARGET	IC50	17650.0	nM	10.1016/j.bmc.2016.09.034
None	NON-PROTEIN TARGET	IC50	25000.0	nM	10.1016/j.ejmech.2010.05.048
None	NON-PROTEIN TARGET	IC50	29810.0	nM	10.1016/j.ejmech.2016.06.021
None	NON-PROTEIN TARGET	IC50	59130.0	nM	10.1016/j.ejmech.2016.06.021
None	NON-PROTEIN TARGET	IC50	61000.0	nM	10.1016/j.bmc.2008.06.046
None	NON-PROTEIN TARGET	IC50	61000.0	nM	10.1021/jm020498a
None	NON-PROTEIN TARGET	IC50	100000.0	nM	10.1016/j.ejmech.2016.06.021
None	NON-PROTEIN TARGET	IC50	nan	None	10.1016/j.bmc.2010.10.042
None	NON-PROTEIN TARGET	IC50	nan	None	10.1016/j.bmc.2011.06.067
None	NON-PROTEIN TARGET	IC50	nan	None	10.1016/j.ejmech.2010.05.048
None	NON-PROTEIN TARGET	LD50	20.0	nM	10.1016/j.bmcl.2010.06.144
None	NON-PROTEIN TARGET	Potency	794.3	nM	None
None	NON-PROTEIN TARGET	Potency	1000.0	nM	None
None	NON-PROTEIN TARGET	Potency	1122.0	nM	None
None	NON-PROTEIN TARGET	Potency	1412.5	nM	None
None	NON-PROTEIN TARGET	T/C	130.0	%	10.1021/jm00045a007
None	NON-PROTEIN TARGET	T/C	142.0	%	10.1021/jm00045a007
None	NON-PROTEIN TARGET	T/C	144.0	%	10.1021/jm00045a007
None	NON-PROTEIN TARGET	T/C	176.0	%	10.1021/jm00045a007
None	No relevant target	Drug metabolism	nan	None	10.1016/j.bmcl.2016.04.056
None	No relevant target	LogP	1.67	None	10.1021/jm101655d
None	No relevant target	LogP	1.74	None	10.1016/j.ejmech.2020.112551
None	No relevant target	LogP	1.74	None	10.1021/acs.jmedchem.8b01938
None	No relevant target	solubility	nan	None	10.1016/j.ejmech.2021.113544
None	No relevant target	Solubility	0.69	ug.mL-1	10.1016/j.bmcl.2018.12.059
None	No relevant target	Solubility	2.5	ug.mL-1	10.1016/j.ejmech.2020.112551
None	No relevant target	Solubility	2.5	ug.mL-1	10.1021/acs.jmedchem.8b01938
None	No relevant target	Solubility	2.5	ug.mL-1	10.1021/jm901029n
None	No relevant target	Solubility	2.7	ug.mL-1	10.1016/j.bmcl.2011.01.013
None	No relevant target	Solubility	3.0	ug.mL-1	10.1016/j.bmcl.2016.04.056
None	No relevant target	Solubility	5.0	ug.mL-1	10.1021/jm00007a008
None	No relevant target	Solubility	60.0	ug.mL-1	10.1016/j.ejmech.2020.112509
None	No relevant target	Stability	40.0	%	10.1016/j.ejmech.2012.05.002
None	No relevant target	Stability	42.7	%	10.1021/jm400906z
None	No relevant target	T1/2	96.0	hr	10.1016/j.bmc.2015.12.020
None	Nucleic Acid	Activity	nan	None	10.1021/jm1005447
None	Nucleic Acid	Activity	nan	None	10.1021/np0004606
None	Nucleic Acid	Activity	nan	None	10.1021/np50078a006
None	Nucleic Acid	Inhibition	76.0	%	10.1021/jm00165a014
None	Nucleic Acid	Inhibition	85.0	%	10.1021/jm00165a014
None	Panel (10 carcinoma cell lines)	Inhibition	nan	%	10.1016/j.bmcl.2006.03.029
None	Panel (56 tumour cell lines)	IC50	40.0	nM	10.1016/s0960-894x(00)00005-6
None	Unchecked	Activity	0.0	%	10.1016/j.ejmech.2018.01.020
None	Unchecked	Activity	0.2	None	10.1016/j.ejmech.2008.09.048
None	Unchecked	Activity	17.56	%	10.1021/np3003468
None	Unchecked	Activity	17.96	%	10.1021/np3003468
None	Unchecked	Activity	48.0	%	10.1016/j.ejmech.2018.01.020
None	Unchecked	Activity	53.0	%	10.1021/acs.jmedchem.1c01362
None	Unchecked	Activity	100.0	%	10.1016/S0960-894X(01)80158-X
None	Unchecked	Activity	nan	None	10.1021/acs.jmedchem.0c00894
None	Unchecked	Activity	nan	None	10.1021/acs.jnatprod.6b00750
None	Unchecked	Activity	nan	None	10.1021/jm8000423
None	Unchecked	Activity	nan	None	10.1021/jm801573v
None	Unchecked	Activity	nan	None	10.1021/np960018g
None	Unchecked	Apoptosis	37.0	%	10.1021/jm049238e
None	Unchecked	Drug metabolism	5.0	%	10.1016/j.ejmech.2020.112509
None	Unchecked	Drug metabolism	93.0	%	10.1016/j.ejmech.2020.112509
None	Unchecked	EC50	100.0	nM	None
None	Unchecked	EC50	134.0	nM	None
None	Unchecked	EC50	700.0	nM	10.1016/j.bmcl.2021.128289
None	Unchecked	EC50	2000.0	nM	10.1016/j.bmcl.2012.08.019
None	Unchecked	Enhancement	1.0	uM	10.1016/S0960-894X(97)10181-0
None	Unchecked	GI50	4730.0	nM	10.1016/j.ejmech.2019.05.074
None	Unchecked	GI50	4730.0	nM	10.1021/acs.jmedchem.8b00639
None	Unchecked	GI50	7530.0	nM	10.1016/j.ejmech.2018.04.040
None	Unchecked	IC50	0.32	nM	10.1021/acs.jnatprod.8b00589
None	Unchecked	IC50	3.0	nM	10.1021/acs.jmedchem.9b01626
None	Unchecked	IC50	10.0	nM	10.1016/j.bmcl.2021.127954
None	Unchecked	IC50	15.7	nM	10.1016/j.bmcl.2017.02.066
None	Unchecked	IC50	15.7	nM	10.1016/j.bmcl.2017.09.012
None	Unchecked	IC50	45.0	nM	10.1016/j.bmcl.2021.127954
None	Unchecked	IC50	75.0	nM	10.1016/j.bmcl.2021.127954
None	Unchecked	IC50	210.0	nM	10.1016/j.bmc.2017.06.030
None	Unchecked	IC50	250.0	nM	10.1016/j.ejmech.2020.112670
None	Unchecked	IC50	450.0	nM	10.1021/acsmedchemlett.0c00131
None	Unchecked	IC50	700.0	nM	10.1021/acs.jmedchem.9b01626
None	Unchecked	IC50	770.0	nM	10.1016/j.bmcl.2018.10.014
None	Unchecked	IC50	1000.0	nM	10.1016/j.bmc.2017.04.030
None	Unchecked	IC50	1840.0	nM	10.1016/j.ejmech.2017.09.005
None	Unchecked	IC50	1920.0	nM	10.1016/j.ejmech.2018.01.020
None	Unchecked	IC50	3000.0	nM	10.1021/np0004606
None	Unchecked	IC50	12340.0	nM	10.1016/j.ejmech.2017.09.009
None	Unchecked	IC50	25000.0	nM	10.1016/j.ejmech.2015.07.007
None	Unchecked	IC50	75690.0	nM	10.1016/j.ejmech.2018.04.033
None	Unchecked	IC50	100000.0	nM	10.1021/jm1005447
None	Unchecked	IC50	300000.0	nM	10.1021/np0004606
None	Unchecked	IC50	500000.0	nM	10.1021/ml5001933
None	Unchecked	IC50	1000000.0	nM	10.1021/np058007n
None	Unchecked	IC50	nan	None	10.1016/j.ejmech.2016.09.017
None	Unchecked	IC50	nan	None	10.1016/j.ejmech.2018.10.065
None	Unchecked	IC50	nan	None	None
None	Unchecked	IC50 ratio	1.4	None	10.1021/jm970044r
None	Unchecked	IC50 ratio	2.0	None	10.1021/jm970044r
None	Unchecked	Inhibition	0.0	%	10.1021/jm1005447
None	Unchecked	Inhibition	1.0	uM	10.1016/S0960-894X(97)10181-0
None	Unchecked	Inhibition	26.3	%	10.1016/j.bmc.2012.06.034
None	Unchecked	Inhibition	41.0	%	10.1016/j.bmcl.2009.11.041
None	Unchecked	Inhibition	54.0	%	10.1016/j.bmcl.2009.11.041
None	Unchecked	Inhibition	61.0	%	10.1128/aac.00650-07
None	Unchecked	Inhibition	63.1	%	10.1016/j.bmc.2012.06.034
None	Unchecked	Inhibition	63.3	%	10.1016/j.bmcl.2007.12.053
None	Unchecked	Inhibition	73.0	%	10.1016/j.ejmech.2010.05.048
None	Unchecked	Inhibition	80.0	%	10.1016/j.ejmech.2010.11.046
None	Unchecked	Inhibition	81.0	%	10.1016/j.ejmech.2015.07.007
None	Unchecked	Inhibition	81.3	%	10.1016/j.bmc.2008.02.036
None	Unchecked	Inhibition	84.1	%	10.1016/j.bmcl.2007.12.053
None	Unchecked	Inhibition	nan	%	10.1016/j.bmc.2010.03.039
None	Unchecked	Inhibition	nan	%	10.1016/j.bmc.2011.05.012
None	Unchecked	Inhibition	nan	%	10.1016/j.bmc.2011.08.006
None	Unchecked	Inhibition	nan	%	10.1016/j.bmc.2015.07.011
None	Unchecked	Inhibition	nan	%	10.1016/j.bmcl.2009.03.042
None	Unchecked	Inhibition	nan	%	10.1016/j.ejmech.2012.07.050
None	Unchecked	Inhibition	nan	%	10.1016/j.ejmech.2012.12.039
None	Unchecked	Inhibition	nan	%	10.1016/j.ejmech.2016.03.031
None	Unchecked	Inhibition	nan	%	10.1016/j.ejmech.2016.06.021
None	Unchecked	Inhibition	nan	%	10.1016/j.ejmech.2016.09.017
None	Unchecked	Inhibition	nan	%	10.1016/j.ejmech.2018.10.065
None	Unchecked	Inhibition	nan	%	10.1021/jm400719y
None	Unchecked	Inhibition	nan	%	10.1038/nchembio873
None	Unchecked	Inhibition	nan	%	10.1039/C8MD00278A
None	Unchecked	Ki	nan	None	None
None	Unchecked	MDR ratio	1.0	None	10.1021/jm00003a001
None	Unchecked	MED	0.03	ug ml-1	10.1021/np960336f
None	Unchecked	Potency	20.6	nM	None
None	Unchecked	Potency	25.1	nM	None
None	Unchecked	Potency	44.7	nM	None
None	Unchecked	Potency	316.2	nM	None
None	Unchecked	Potency	580.5	nM	None
None	Unchecked	Potency	1000.0	nM	None
None	Unchecked	Potency	1412.5	nM	None
None	Unchecked	Potency	1584.9	nM	None
None	Unchecked	Potency	1778.3	nM	None
None	Unchecked	Potency	2238.7	nM	None
None	Unchecked	Potency	3548.1	nM	None
None	Unchecked	Potency	3981.1	nM	None
None	Unchecked	Potency	4466.8	nM	None
None	Unchecked	Potency	5011.9	nM	None
None	Unchecked	Potency	15848.9	nM	None
None	Unchecked	Potency	22387.2	nM	None
None	Unchecked	Potency	28183.8	nM	None
None	Unchecked	Potency	35481.3	nM	None
None	Unchecked	Ratio	1.0	None	10.1021/jm101354u
None	Unchecked	Ratio	1.4	None	10.1021/jm020420u
None	Unchecked	Ratio	2.0	None	10.1021/jm020420u
None	Unchecked	Ratio	3.83	None	10.1021/np3003468
None	Unchecked	Ratio	87.5	None	10.1021/jm980702n
None	Unchecked	Ratio	225.0	None	10.1016/j.ejmech.2019.05.074
None	Unchecked	Ratio	250.0	None	10.1021/jm101354u
None	Unchecked	Ratio CC50/IC50	20.7	None	10.1016/j.ejmech.2016.09.017
None	Unchecked	RatioGI50	8.3	None	10.1016/j.ejmech.2018.04.040
None	Unchecked	RatioGI50	8.3	None	10.1021/acs.jmedchem.8b00639
None	Unchecked	RatioGI50	9.2	None	10.1021/acs.jmedchem.1c00318
None	Unchecked	RatioGI50	225.0	None	10.1021/acs.jmedchem.8b00639
None	Unchecked	RatioGI50	396.3	None	10.1016/j.ejmech.2018.04.040
None	Unchecked	Ratio IC50	0.5	None	10.1016/j.ejmech.2015.11.037
None	Unchecked	Ratio IC50	0.53	None	10.1016/j.bmcl.2018.10.014
None	Unchecked	Ratio IC50	1.17	None	10.1016/j.bmc.2017.06.030
None	Unchecked	Ratio IC50	3.24	None	10.1016/j.ejmech.2020.112768
None	Unchecked	Ratio IC50	3.7	None	10.1016/j.bmc.2017.02.005
None	Unchecked	Ratio IC50	24.0	None	10.1021/acs.jmedchem.1c01411
None	Unchecked	Ratio IC50	48.0	None	10.1016/j.bmc.2012.05.030
None	Unchecked	Ratio IC50	nan	None	10.1016/j.ejmech.2013.06.004
None	Unchecked	Ratio IC50	nan	None	10.1016/j.ejmech.2015.05.044

Metabolism Information

AKRT ID	Reaction	Reaction Link ID
AKRT001919	C=C[C@H]1[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)OC=C2C(=O)N3Cc4cc5ccccc5nc4[C@@H]3C[C@H]21>>CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1	RXN-14036