Eburnamine
AlkaPlorer ID: AK004185
Synonym: '', '(+)-Isoeburnamine', 'Eburnamenin-14-ol, 14,15-dihydro-, (14alpha)-', '(-)-Eburnamine', 'Eburnamine', '16-Epivincanol'
IUPAC Name: (15S,17S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-ol
Structure
SMILES: CC[C@@]12CCCN3CCC4=C([C@@H]31)N(C1=CC=CC=C41)[C@@H](O)C2
InChI: InChI=1S/C19H24N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,16,18,22H,2,5,8-12H2,1H3/t16-,18+,19-/m0/s1
InChIKey: HONLKDDLTAZVQV-UHOSZYNNSA-N
Reference
Alcaloïdes Indoliques Monomères de<i>Kopsia officinalis</i>
PubChem CID: 10017481
CAS: 19877-89-5
LOTUS: LTS0086433
SuperNatural Ⅲ: SN0131232-06
NPASS: NPC160889
data_source: manually
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 296.41400000000004
TPSA？: 28.4
MolLogP？: 3.625300000000003
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Aortic artery | EC50 | 10000.0 | nM | 10.1021/acs.jnatprod.9b00925 |