D-argininium(1+)
AlkaPlorer ID: AK004215
Synonym: '', 'L-Arginine', '(S)-2-amino-5-guanidinopentanoic acid', 'L-arginine monocation', 'D-arginine monocation', '(2R)-2-amino-5-(carbamimidamido)pentanoic acid', 'L-arginine', 'D-arginine', '(S)-2-Amino-5-guanidinovaleric acid', '(2S)-2-amino-5-guanidinopentanoic acid', 'R', '2-Amino-5-guanidinovaleric acid', 'arginine', 'Arginine', '(2S)-2-ammonio-5-guanidiniopentanoate', 'L-arginine cation', '2-amino-5-guanidinopentanoic acid', 'Arginin', '(R)-2-amino-5-guanidinopentanoic acid', 'L-Arginine L-Glutamate', 'L-(+)-arginine', 'arginine(1+)', 'D-2-Amino-5-guanidinovaleric acid', '(2S)-2-amino-5-guanidinopentanoate', '(2S)-2-amino-5-(carbamimidamido)pentanoic acid', 'D-Arginin', 'Harg', 'Rubradirin B', '(2R)-2-amino-5-guanidinopentanoic acid', 'L-Arg', 'D-argininium(1+)', 'D-Arginine', 'DAR', 'Arg', '(2S)-2-amino-5-(carbamimidamido)pentanoate', 'L-argininium(1+)', '2-amino-5-(carbamimidamido)pentanoic acid', '74-79-3', '(2R)-2-ammonio-5-guanidiniopentanoate', 'L-Arginin'
IUPAC Name: (2R)-2-amino-5-(diaminomethylideneamino)pentanoic acid
Structure
SMILES: N=C(N)NCCC[C@@H](N)C(=O)O
InChI: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1
InChIKey: ODKSFYDXXFIFQN-SCSAIBSYSA-N
Reference
PubChem CID: 135705201
CAS: 1119-34-2
LOTUS: LTS0114277
SuperNatural Ⅲ: SN0262438-02
NPASS: NPC320723
Source
Properties Information
Molecule Weight: 174.204
TPSA？: 125.22
MolLogP？: -1.338429999999999
Number of H-Donors: 5
Number of H-Acceptors: 3
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | 4'-phosphopantetheinyl transferase ffp | Potency | 35481.3 | nM | None |
| Homo sapiens | Angiotensin-converting enzyme | IC50 | nan | None | 10.1021/acs.jnatprod.5b00092 |
| Homo sapiens | Menin/Histone-lysine N-methyltransferase MLL | Potency | 39810.7 | nM | None |
| Rattus norvegicus | GH3 | AUC | 2470.16 | ng.hr.mL-1 | 10.1021/jm060005s |
| Rattus norvegicus | GH3 | permeability | nan | None | 10.1021/jm060005s |
| Severe acute respiratory syndrome coronavirus 2 | Replicase polyprotein 1ab | Inhibition | -1.574 | % | 10.6019/CHEMBL4495564 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | -7.01 | % | 10.21203/rs.3.rs-23951/v1 |
| Severe acute respiratory syndrome coronavirus 2 | SARS-CoV-2 | Inhibition | 0.01 | % | 10.6019/CHEMBL4495565 |
| None | AEC | Activity | nan | None | 10.1021/jm060005s |