Haemanthidine
AlkaPlorer ID: AK004552
Synonym: 'Pancratine', '', '6-Hydroxycrinamine', 'Hemanthidine', 'Haemanthidine'
IUPAC Name: (1R,11R,13S,15S,18R)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraene-11,18-diol
Structure
SMILES: CO[C@@H]1C=C[C@]23C4=CC5=C(C=C4[C@@H](O)N(C[C@@H]2O)[C@H]3C1)OCO5
InChI: InChI=1S/C17H19NO5/c1-21-9-2-3-17-11-6-13-12(22-8-23-13)5-10(11)16(20)18(7-15(17)19)14(17)4-9/h2-3,5-6,9,14-16,19-20H,4,7-8H2,1H3/t9-,14+,15+,16-,17-/m1/s1
InChIKey: ZSTPNQLNQBRLQF-BDFRYUFDSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Leucojum aestivum | Leucojum | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Narcissus tazetta | Narcissus | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Pancratium maritimum | Pancratium | Amaryllidaceae | Asparagales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 317.3410000000001
TPSA？: 71.39000000000001
MolLogP？: 0.6775999999999998
Number of H-Donors: 2
Number of H-Acceptors: 6
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 0.34 | ug.mL-1 | 10.1016/j.bmc.2009.02.050 |