2-METHYLINDOL
AlkaPlorer ID: AK004571
Synonym: '2-Methylindole'
IUPAC Name: 2-methyl-1H-indole
Structure
SMILES: CC1=CC2=CC=CC=C2N1
InChI: InChI=1S/C9H9N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-6,10H,1H3
InChIKey: BHNHHSOHWZKFOX-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 131.17799999999997
TPSA？: 15.79
MolLogP？: 2.4763200000000003
Number of H-Donors: 1
Number of H-Acceptors: 0
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Electrophorus electricus | Acetylcholinesterase | Inhibition | 17.97 | % | 10.1016/j.bmcl.2012.02.057 |
| Homo sapiens | Androgen Receptor | Inhibition | 16.0 | % | 10.1073/pnas.0708036104 |
| Homo sapiens | PI3-kinase p110-alpha/p85-alpha | Inhibition | 25.0 | % | 10.1016/j.bmc.2017.01.012 |
| Homo sapiens | PI3-kinase p110-alpha subunit | Inhibition | 25.0 | % | 10.1016/j.bmc.2017.01.012 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | nan | % | 10.1021/jm00214a015 |
| None | Calvarial osteoblast | Activity | nan | None | 10.1016/j.ejmech.2022.114813 |