Navigation

name Structure Reference Source Properties Activities Metabolism

ribavirin

AlkaPlorer ID: AK004693

Synonym: None

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide

Structure

SMILES: NC(=O)C1=NN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=N1

copy

InChI: InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

copy

InChIKey: IWUCXVSUMQZMFG-AFCXAGJDSA-N

copy

Reference

PubChem CID: 37542

CAS: 36791-04-5

SuperNatural Ⅲ: SN0157351-05

NPASS: NPC332914

Properties Information

Molecule Weight: 244.207

TPSA？: 143.72000000000003

MolLogP？: -3.0115

Number of H-Donors: 4

Number of H-Acceptors: 8

RingCount: 2

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Avian orthoavulavirus 1 Newcastle disease virus Activity 15.0 mM 10.1016/S0960-894X(01)80822-2
Avian orthoavulavirus 1 Newcastle disease virus Activity 40.0 mM 10.1016/S0960-894X(01)80822-2
Avian orthoavulavirus 1 Newcastle disease virus Activity 52.0 mM 10.1016/S0960-894X(01)80822-2
Avian orthoavulavirus 1 Newcastle disease virus MIC 3.0 ug.mL-1 10.1016/j.ejmech.2018.08.023
Bacillus subtilis Bacillus subtilis MIC nan None 10.1021/jm00199a015
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 1300.0 nM 10.1016/j.bmcl.2014.03.012
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 4620.0 nM 10.1016/j.ejmech.2007.10.023
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 7000.0 nM 10.1016/j.bmc.2009.05.020
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 7000.0 nM 10.1016/j.bmc.2010.02.037
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 8000.0 nM 10.1016/j.bmc.2014.06.043
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 8000.0 nM 10.1016/j.bmc.2015.09.035
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 19000.0 nM 10.1016/j.bmcl.2015.04.006
Bovine viral diarrhea virus 1 Bovine viral diarrhea virus 1 EC50 20000.0 nM 10.1016/j.ejmech.2017.09.060
Camelpox virus Camelpox virus IC50 215000.0 nM 10.1016/j.bmc.2008.11.075
Canis lupus familiaris MDCK Activity 100.0 ug ml-1 10.1016/j.ejmech.2010.07.058
Canis lupus familiaris MDCK CC50 100.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Canis lupus familiaris MDCK CC50 100.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Canis lupus familiaris MDCK CC50 100.0 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK CC50 320.0 ug.mL-1 10.1016/j.ejmech.2015.08.005
Canis lupus familiaris MDCK CC50 20000.0 nM 10.1016/j.bmcl.2021.127926
Canis lupus familiaris MDCK CC50 20000.0 nM 10.1021/ml300279b
Canis lupus familiaris MDCK CC50 50000.0 nM 10.1016/j.ejmech.2021.113683
Canis lupus familiaris MDCK CC50 58000.0 nM 10.1016/j.ejmech.2020.112223
Canis lupus familiaris MDCK CC50 67000.0 nM 10.1039/d3md00055a
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1007/s00044-012-0184-x
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmc.2008.08.041
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmc.2012.09.064
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmc.2015.07.039
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmc.2016.04.010
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmc.2019.115130
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmcl.2014.06.018
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmcl.2019.02.027
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmcl.2019.04.042
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.bmcl.2023.129174
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2009.12.002
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2012.03.007
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2015.02.028
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2017.04.070
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2018.05.059
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2018.08.058
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1016/j.ejmech.2019.111739
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1021/acs.jmedchem.7b00908
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1021/acs.jmedchem.8b00617
Canis lupus familiaris MDCK CC50 100000.0 nM 10.1021/jm801470b
Canis lupus familiaris MDCK CC50 200000.0 nM 10.1016/j.ejmech.2015.02.006
Canis lupus familiaris MDCK CC50 200000.0 nM 10.1016/j.ejmech.2015.09.037
Canis lupus familiaris MDCK CC50 200000.0 nM 10.1016/j.ejmech.2021.113591
Canis lupus familiaris MDCK CC50 200000.0 nM 10.1021/acsmedchemlett.5b00109
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1016/j.ejmech.2017.06.015
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1016/j.ejmech.2018.08.032
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1016/j.ejmech.2020.112944
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1016/j.ejmech.2021.113494
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1021/acs.jmedchem.5b00012
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1021/acs.jmedchem.5b01935
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1021/jm401560v
Canis lupus familiaris MDCK CC50 250000.0 nM 10.1021/jm500300r
Canis lupus familiaris MDCK CC50 300000.0 nM 10.1021/acs.jnatprod.2c00766
Canis lupus familiaris MDCK CC50 323500.0 nM 10.1016/j.ejmech.2013.05.044
Canis lupus familiaris MDCK CC50 500000.0 ug.mL-1 10.1016/j.bmcl.2007.11.117
Canis lupus familiaris MDCK CC50 512000.0 nM 10.1016/j.bmc.2008.06.049
Canis lupus familiaris MDCK CC50 1000000.0 nM 10.1021/acsmedchemlett.3c00048
Canis lupus familiaris MDCK CC50 1365500.0 nM 10.1016/j.bmcl.2018.07.029
Canis lupus familiaris MDCK CC50 2000000.0 nM 10.1039/C6MD00657D
Canis lupus familiaris MDCK CC50 2130000.0 nM 10.1016/j.bmcl.2018.04.057
Canis lupus familiaris MDCK CC50 2130000.0 nM 10.1016/j.bmcl.2020.127653
Canis lupus familiaris MDCK CC50 2130000.0 nM 10.1016/j.bmcl.2020.127677
Canis lupus familiaris MDCK CC50 2130000.0 nM 10.1039/C8MD00442K
Canis lupus familiaris MDCK CC50 2336000.0 nM 10.1128/aac.01051-06
Canis lupus familiaris MDCK CC50 4095000.0 nM 10.1016/j.bmcl.2023.129219
Canis lupus familiaris MDCK CC50 nan None 10.1016/j.bmcl.2018.03.080
Canis lupus familiaris MDCK CC50 nan None 10.1021/np050498o
Canis lupus familiaris MDCK CTD50 2000.0 uM 10.1016/j.bmcl.2012.09.084
Canis lupus familiaris MDCK CTD50 2000.0 uM 10.1016/j.bmcl.2019.126745
Canis lupus familiaris MDCK EC50 2.1 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 2.2 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 5.5 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 6.1 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 7.9 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 8.3 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 8.5 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 11.7 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 34.2 ug.mL-1 10.1016/S0960-894X(97)10154-8
Canis lupus familiaris MDCK EC50 3700.0 nM 10.1016/s0960-894x(03)00231-2
Canis lupus familiaris MDCK IC50 4.0 ug.mL-1 10.1021/jm00075a030
Canis lupus familiaris MDCK IC50 62.5 ug.mL-1 10.1021/np030470h
Canis lupus familiaris MDCK IC50 200.0 ug.mL-1 10.1021/jm00075a030
Canis lupus familiaris MDCK IC50 200.0 ug.mL-1 10.1021/np960613i
Canis lupus familiaris MDCK IC50 4900.0 nM 10.1021/jm00018a015
Canis lupus familiaris MDCK IC50 16300.0 nM 10.1021/jm00018a015
Canis lupus familiaris MDCK IC50 1310000.0 nM 10.1016/j.bmcl.2010.02.074
Canis lupus familiaris MDCK ID50 3.1 ug ml-1 10.1021/jm00166a020
Canis lupus familiaris MDCK MCC 100.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Canis lupus familiaris MDCK MCC 100.0 ug.mL-1 10.1021/jm00188a013
Canis lupus familiaris MDCK MCC 200.0 ug.mL-1 10.1021/jm00095a019
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.bmc.2009.01.009
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.bmc.2012.03.004
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.bmc.2012.09.064
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.bmcl.2007.04.108
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.bmcl.2014.06.018
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.ejmech.2010.08.009
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.ejmech.2012.10.030
Canis lupus familiaris MDCK MCC 20000.0 nM 10.1016/j.ejmech.2018.05.059
Canis lupus familiaris MDCK MCC 35000.0 nM 10.1021/acs.jmedchem.8b00617
Canis lupus familiaris MDCK MCC 59000.0 nM 10.1021/acs.jmedchem.8b00617
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1007/s00044-012-0184-x
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmc.2008.08.041
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmc.2010.02.015
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmc.2011.04.016
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmc.2015.12.008
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmc.2018.05.034
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmc.2019.115130
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.bmcl.2012.09.079
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2012.03.007
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2013.05.046
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2013.06.036
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2015.02.028
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2015.06.024
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2017.04.070
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2018.08.058
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2019.111739
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2020.112223
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1021/acs.jmedchem.7b00908
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1021/jm401340p
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1021/jm801470b
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1021/ml300279b
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1039/c1md00094b
Canis lupus familiaris MDCK MCC50 276.9 uM 10.1016/s0960-894x(03)00231-2
Canis lupus familiaris MDCK MCC50 1024.6 uM 10.1016/s0960-894x(01)00388-2
Canis lupus familiaris MDCK MIC50 1.2 ug.mL-1 10.1021/jm00044a010
Canis lupus familiaris MDCK MIC50 4.0 ug.mL-1 10.1021/jm00044a010
Canis lupus familiaris MDCK MIC50 19.0 ug.mL-1 10.1021/jm950891z
Canis lupus familiaris MDCK MIC50 200.0 ug.mL-1 10.1021/jm00044a010
Canis lupus familiaris MDCK MIC50 250.0 ug.mL-1 10.1021/jm950891z
Canis lupus familiaris MDCK MIC50 31100.0 nM 10.1016/s0960-894x(99)00631-9
Canis lupus familiaris MDCK MIC50 41000.0 nM 10.1016/s0960-894x(99)00631-9
Canis lupus familiaris MDCK MIC50 122900.0 nM 10.1016/s0960-894x(01)00388-2
Canis lupus familiaris MDCK MIC50 614800.0 nM 10.1016/s0960-894x(01)00388-2
Canis lupus familiaris MDCK MNCC nan None 10.1016/j.bmc.2008.06.049
Canis lupus familiaris MDCK MNCC nan None 10.1021/np050498o
Canis lupus familiaris MDCK MTC 32.0 ug ml-1 10.1021/jm00166a020
Canis lupus familiaris MDCK MTC 819.6 uM 10.1021/jm00018a015
Canis lupus familiaris MDCK MTC50 1025.0 uM 10.1016/s0960-894x(99)00631-9
Canis lupus familiaris MDCK TC50 256.1 uM 10.1021/np800542t
Canis lupus familiaris MDCK TC50 1164.0 ug ml-1 10.1016/j.ejmech.2014.02.029
Canis lupus familiaris MDCK TC50 1164.0 umol/L 10.1021/acs.jnatprod.6b00585
Canis lupus familiaris MDCK TC50 1164.1 ug ml-1 10.1016/j.bmcl.2016.06.011
Canis lupus familiaris MDCK TC50 1278.0 uM 10.1016/j.bmcl.2012.01.056
Canis lupus familiaris MDCK TC50 3277.4 ug ml-1 10.1016/j.bmcl.2015.12.100
Canis lupus familiaris MDCK TC50 4764.5 uM 10.1016/j.bmcl.2019.08.009
Canis lupus familiaris MDCK TC50 4766.8 uM 10.1016/j.ejmech.2012.07.008
Canis lupus familiaris MDCK TC50 4766.8 uM 10.1021/acs.jnatprod.5b00325
Canis lupus familiaris MDCK TC50 4771.0 uM 10.1016/j.ejmech.2020.112577
Canis lupus familiaris MDCK Therapeutic index 10.3 None 10.1021/jm00166a020
Canis lupus familiaris MDCK Virus rating 3.4 None 10.1021/jm00166a020
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chikungunya virus Chikungunya virus Activity nan None 10.1016/j.bmcl.2019.126881
Chikungunya virus Chikungunya virus EC 10.0 ug ml-1 10.1021/acs.jnatprod.2c00464
Chikungunya virus Chikungunya virus EC50 1890.0 nM 10.1021/acs.jmedchem.7b00180
Chikungunya virus Chikungunya virus EC50 1970.0 nM 10.1021/acs.jmedchem.7b00180
Chikungunya virus Chikungunya virus EC50 2420.0 nM 10.1016/j.bmcl.2019.126881
Chikungunya virus Chikungunya virus EC50 9710.0 nM 10.1021/acs.jmedchem.7b00180
Chikungunya virus Chikungunya virus EC50 16200.0 nM 10.1021/acs.jmedchem.7b00180
Chikungunya virus Chikungunya virus EC50 341000.0 nM 10.1016/j.bmc.2017.06.049
Chikungunya virus Chikungunya virus FC 31.62 None 10.1021/acs.jnatprod.2c00464
Chikungunya virus Chikungunya virus IC50 3060.0 nM 10.1016/j.bmc.2017.06.049
Chikungunya virus Chikungunya virus Inhibition 97.0 % 10.1021/acs.jnatprod.1c00199
Chlorocebus sabaeus Vero Activity 1.1 pmol 10.1128/aac.00790-06
Chlorocebus sabaeus Vero Activity 3.2 pmol 10.1128/aac.00790-06
Chlorocebus sabaeus Vero Activity 6.5 pmol 10.1128/aac.00790-06
Chlorocebus sabaeus Vero Activity 22.0 pmol 10.1128/aac.00790-06
Chlorocebus sabaeus Vero Activity 40.0 % 10.1128/aac.00790-06
Chlorocebus sabaeus Vero Activity 50.0 % 10.1128/aac.00790-06
Chlorocebus sabaeus Vero Activity 250.0 ug ml-1 10.1016/j.ejmech.2010.07.058
Chlorocebus sabaeus Vero Activity 400.0 ug ml-1 10.1016/j.ejmech.2007.04.010
Chlorocebus sabaeus Vero Activity nan None 10.1128/aac.00790-06
Chlorocebus sabaeus Vero CC50 400.0 ug.mL-1 10.1021/jm9507901
Chlorocebus sabaeus Vero CC50 100000.0 nM 10.1016/j.bmc.2009.05.020
Chlorocebus sabaeus Vero CC50 100000.0 nM 10.1016/j.bmc.2010.02.037
Chlorocebus sabaeus Vero CC50 100000.0 nM 10.1021/acs.jmedchem.9b00775
Chlorocebus sabaeus Vero CC50 156000.0 nM 10.1128/aac.00356-07
Chlorocebus sabaeus Vero CC50 250000.0 nM 10.1016/j.ejmech.2009.12.002
Chlorocebus sabaeus Vero CC50 297000.0 nM 10.1016/j.bmcl.2019.126881
Chlorocebus sabaeus Vero CC50 300000.0 nM 10.1021/acs.jnatprod.1c00199
Chlorocebus sabaeus Vero CC50 400000.0 nM 10.1016/j.bmcl.2018.12.063
Chlorocebus sabaeus Vero CC50 400000.0 nM 10.1016/j.ejmech.2020.112862
Chlorocebus sabaeus Vero CC50 470500.0 nM 10.1016/j.ejmech.2022.114275
Chlorocebus sabaeus Vero CC50 500000.0 nM 10.1021/jm060030y
Chlorocebus sabaeus Vero CC50 850000.0 nM 10.1016/j.bmcl.2007.02.026
Chlorocebus sabaeus Vero CC50 1000000.0 nM 10.1021/np500124e
Chlorocebus sabaeus Vero CC50 1245000.0 nM 10.1016/j.bmc.2022.116858
Chlorocebus sabaeus Vero CC50 1622000.0 nM 10.1016/j.bmc.2017.06.049
Chlorocebus sabaeus Vero CC50 3562000.0 nM 10.1016/j.bmcl.2023.129219
Chlorocebus sabaeus Vero CC50 3931000.0 nM 10.1016/j.bmcl.2023.129219
Chlorocebus sabaeus Vero CC50 4094000.0 nM 10.1016/j.bmcl.2023.129219
Chlorocebus sabaeus Vero CC50 4100000.0 nM 10.1128/aac.01074-08
Chlorocebus sabaeus Vero CC50 8189670.0 nM 10.1016/j.ejmech.2013.07.053
Chlorocebus sabaeus Vero CC50 nan None 10.1016/j.bmcl.2023.129174
Chlorocebus sabaeus Vero CC50 nan None 10.1021/np050498o
Chlorocebus sabaeus Vero EC50 40000.0 nM 10.1021/jm0108350
Chlorocebus sabaeus Vero EC50 64000.0 nM 10.1021/jm980163m
Chlorocebus sabaeus Vero EC50 119000.0 nM 10.1021/jm051229y
Chlorocebus sabaeus Vero EC50 196000.0 nM 10.1021/jm0108350
Chlorocebus sabaeus Vero EC50 1600000.0 nM 10.1021/jm0108350
Chlorocebus sabaeus Vero EC50 1600000.0 nM 10.1021/jm980163m
Chlorocebus sabaeus Vero ED50 3.3e-05 M 10.1021/jm00146a007
Chlorocebus sabaeus Vero ED50 8.5e-05 M 10.1021/jm00146a007
Chlorocebus sabaeus Vero ED50 0.00016 M 10.1021/jm00146a007
Chlorocebus sabaeus Vero ED50 0.00019 M 10.1021/jm00146a007
Chlorocebus sabaeus Vero IC50 5.2 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 6.4 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 20.0 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 160.0 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 235.0 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 250.0 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 400.0 ug.mL-1 10.1021/jm00075a030
Chlorocebus sabaeus Vero IC50 447.8 ug.mL-1 10.1016/j.bmcl.2004.10.087
Chlorocebus sabaeus Vero IC50 286800.0 nM 10.1021/jm00018a015
Chlorocebus sabaeus Vero IC50 400000.0 nM 10.1016/j.ejmech.2010.11.012
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.ejmech.2015.11.009
Chlorocebus sabaeus Vero IC50 nan None 10.1021/acs.jmedchem.8b01403
Chlorocebus sabaeus Vero MCC 7.0 ug.mL-1 10.1021/jm00152a007
Chlorocebus sabaeus Vero MCC 20.0 ug.mL-1 10.1021/jm00152a007
Chlorocebus sabaeus Vero MCC 48.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Chlorocebus sabaeus Vero MCC 70.0 ug.mL-1 10.1021/jm00152a007
Chlorocebus sabaeus Vero MCC 200.0 ug.mL-1 10.1021/jm0707166
Chlorocebus sabaeus Vero MCC 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Chlorocebus sabaeus Vero MCC 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Chlorocebus sabaeus Vero MCC 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Chlorocebus sabaeus Vero MCC 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm00095a019
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm00125a024
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm00128a011
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm00152a007
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm00369a010
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm00389a005
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm050772b
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm061281+
Chlorocebus sabaeus Vero MCC 400.0 ug.mL-1 10.1021/jm100093p
Chlorocebus sabaeus Vero MCC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1007/s00044-009-9248-y
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1007/s00044-012-0184-x
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.bmc.2008.08.041
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.bmc.2012.03.004
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.bmc.2015.04.079
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.bmc.2015.12.008
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.bmc.2018.05.034
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.ejmech.2012.03.007
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.ejmech.2013.05.046
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.ejmech.2013.06.036
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.ejmech.2015.06.024
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.ejmech.2015.08.008
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1016/j.ejmech.2017.04.070
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1021/jm801470b
Chlorocebus sabaeus Vero MCC 250000.0 nM 10.1039/c1md00094b
Chlorocebus sabaeus Vero MCC nan None 10.1016/j.bmc.2011.04.016
Chlorocebus sabaeus Vero MIC 10.0 ug.mL-1 10.1021/jm00389a005
Chlorocebus sabaeus Vero MIC 16.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Chlorocebus sabaeus Vero MIC 20.0 ug.mL-1 10.1021/jm00095a019
Chlorocebus sabaeus Vero MIC 20.0 ug.mL-1 10.1021/jm00096a012
Chlorocebus sabaeus Vero MIC 20.0 ug.mL-1 10.1021/jm00125a024
Chlorocebus sabaeus Vero MIC 40.0 ug.mL-1 10.1021/jm00095a019
Chlorocebus sabaeus Vero MIC 40.0 ug.mL-1 10.1021/jm00096a012
Chlorocebus sabaeus Vero MIC 70.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Chlorocebus sabaeus Vero MIC 70.0 ug.mL-1 10.1021/jm00095a019
Chlorocebus sabaeus Vero MIC 70.0 ug.mL-1 10.1021/jm00096a012
Chlorocebus sabaeus Vero MIC 70.0 ug.mL-1 10.1021/jm00125a024
Chlorocebus sabaeus Vero MIC 70.0 ug.mL-1 10.1021/jm00389a005
Chlorocebus sabaeus Vero MIC 70.0 ug.mL-1 10.1021/jm960770e
Chlorocebus sabaeus Vero MIC 80.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Chlorocebus sabaeus Vero MIC 100.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Chlorocebus sabaeus Vero MIC 100.0 ug.mL-1 10.1021/jm00096a012
Chlorocebus sabaeus Vero MIC 150.0 ug.mL-1 10.1021/jm00167a011
Chlorocebus sabaeus Vero MIC 150.0 ug.mL-1 10.1021/jm960770e
Chlorocebus sabaeus Vero MIC 240.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Chlorocebus sabaeus Vero MIC 300.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Chlorocebus sabaeus Vero MIC 300.0 ug.mL-1 10.1021/jm960770e
Chlorocebus sabaeus Vero MIC 400.0 ug.mL-1 10.1021/jm00389a005
Chlorocebus sabaeus Vero MIC 400.0 ug.mL-1 10.1021/jm960770e
Chlorocebus sabaeus Vero MIC 500000.0 nM 10.1021/jm0108350
Chlorocebus sabaeus Vero MIC 1600000.0 nM 10.1021/jm0108350
Chlorocebus sabaeus Vero MIC 1600000.0 nM 10.1021/jm980163m
Chlorocebus sabaeus Vero MIC50 20.0 ug.mL-1 10.1021/jm00044a010
Chlorocebus sabaeus Vero MIC50 70.0 ug.mL-1 10.1021/jm00044a010
Chlorocebus sabaeus Vero MIC50 300.0 ug.mL-1 10.1021/jm00044a010
Chlorocebus sabaeus Vero MIC50 400.0 ug.mL-1 10.1021/jm00044a010
Chlorocebus sabaeus Vero MIC50 400.0 ug.mL-1 10.1021/jm950891z
Chlorocebus sabaeus Vero MNCC nan None 10.1021/np050498o
Chlorocebus sabaeus Vero MTC 0.005 M 10.1021/jm00152a016
Chlorocebus sabaeus Vero MTC 5.0 M 10.1021/jm00147a013
Chlorocebus sabaeus Vero MTC 400.0 ug ml-1 10.1021/jm00386a007
Chlorocebus sabaeus Vero MTC 1639.2 uM 10.1021/jm00018a015
Chlorocebus sabaeus Vero Plaque reduction 10.0 % 10.1021/jm00353a012
Chlorocebus sabaeus Vero Plaque reduction 31.0 % 10.1021/jm00353a012
Chlorocebus sabaeus Vero Plaque reduction 61.0 % 10.1021/jm00353a012
Chlorocebus sabaeus Vero SI 2.23 None 10.1016/j.bmcl.2004.10.087
Chlorocebus sabaeus Vero TC50 8.1 uM/ml 10.1021/np400638r
Chlorocebus sabaeus Vero TC50 31.25 uM 10.1016/j.bmcl.2019.126770
Chlorocebus sabaeus Vero TC50 200.0 ug ml-1 10.1016/j.bmc.2018.12.014
Chlorocebus sabaeus Vero TC50 1000.0 ug ml-1 10.1016/j.bmcl.2004.10.087
Chlorocebus sabaeus Vero TC50 6355.68 uM 10.1016/j.bmcl.2017.01.022
Chlorocebus sabaeus Vero TC50 6355.7 uM 10.1016/j.ejmech.2016.09.097
Chlorocebus sabaeus Vero TC50 8189.67 uM 10.1021/acs.jnatprod.5b00325
Chlorocebus sabaeus Vero TC50 8190.0 uM 10.1016/j.bmc.2011.03.007
Chlorocebus sabaeus Vero TC50 8190.0 uM 10.1016/j.bmcl.2011.08.002
Chlorocebus sabaeus Vero TC50 8196.0 uM 10.1021/np500951s
Chlorocebus sabaeus Vero TC50 8197.0 uM 10.1021/ml500525s
Chlorocebus sabaeus Vero Toxic level nan None 10.1021/jm00146a007
Chlorocebus sabaeus Vero Virus rating 0.6 None 10.1021/jm00140a006
Chlorocebus sabaeus Vero Virus rating 0.6 None 10.1021/jm00353a012
Chlorocebus sabaeus Vero Virus rating 0.8 None 10.1021/jm00140a006
Chlorocebus sabaeus Vero Virus rating 1.2 None 10.1021/jm00140a006
Chlorocebus sabaeus Vero Virus rating 1.2 None 10.1021/jm00353a012
Chlorocebus sabaeus Vero Virus rating 1.3 None 10.1021/jm00140a006
Chlorocebus sabaeus Vero Virus rating 1.3 None 10.1021/jm00353a012
Chlorocebus sabaeus Vero 76 CC50 100000.0 nM 10.1016/j.ejmech.2017.09.060
Chlorocebus sabaeus Vero 76 CC50 4094000.0 nM 10.1016/j.bmcl.2023.129219
Chlorocebus sabaeus Vero C1008 Activity 94.5 % 10.1016/j.bmcl.2019.126906
Chlorocebus sabaeus Vero C1008 AUC cytotoxicity 252.5 None 10.1038/s41586-020-2286-9
Chlorocebus sabaeus Vero C1008 CC100 160.0 ug ml-1 10.1021/acs.jnatprod.2c00464
Chlorocebus sabaeus Vero C1008 CC50 100000.0 nM 10.1016/j.bmcl.2019.126906
Chlorocebus sabaeus Vero C1008 CC50 160000.0 nM 10.1021/acs.jnatprod.2c00464
Chlorocebus sabaeus Vero C1008 CC50 200000.0 nM 10.1021/acs.jmedchem.0c00232
Chlorocebus sabaeus Vero C1008 CC50 400000.0 nM 10.1016/j.bmc.2020.115757
Chlorocebus sabaeus Vero C1008 CC50 400000.0 nM 10.1016/j.ejmech.2020.112559
Chlorocebus sabaeus Vero C1008 CC50 400000.0 nM 10.1016/j.ejmech.2021.113157
Chlorocebus sabaeus Vero C1008 CC50 400000.0 nM 10.1016/j.ejmech.2021.113683
Chlorocebus sabaeus Vero C1008 CC50 400000.0 nM 10.1021/acs.jmedchem.0c00606
Chlorocebus sabaeus Vero C1008 CC50 400000.0 nM 10.1021/acs.jmedchem.0c00626
Chlorocebus sabaeus Vero C1008 CC50 nan None 10.1021/acsmedchemlett.8b00583
Chlorocebus sabaeus Vero C1008 MCC 4095000.0 nM 10.1016/j.bmcl.2017.03.100
Chlorocebus sabaeus Vero C1008 pCC50 4.664 None 10.1038/s41586-020-2286-9
Cowpox virus Cowpox virus IC50 410000.0 nM 10.1016/j.bmc.2008.11.075
Coxsackievirus Coxsackievirus EC50 112000.0 nM 10.1016/j.ejmech.2013.05.046
Coxsackievirus Coxsackievirus EC50 112000.0 nM 10.1016/j.ejmech.2015.06.024
Coxsackievirus Coxsackievirus EC50 250000.0 nM 10.1016/j.ejmech.2013.05.046
Coxsackievirus Coxsackievirus EC50 250000.0 nM 10.1016/j.ejmech.2015.06.024
Coxsackievirus Coxsackievirus IC50 222200.0 nM 10.1021/np4000747
Coxsackievirus Coxsackievirus IC50 694600.0 nM 10.1021/ml500525s
Coxsackievirus Coxsackievirus IC50 884900.0 nM 10.1016/j.bmcl.2019.126770
Coxsackievirus Coxsackievirus IC50 910800.0 nM 10.1021/ml500525s
Coxsackievirus Coxsackievirus IC50 1708000.0 nM 10.1021/ml500525s
Coxsackievirus Coxsackievirus IC50 1951000.0 nM 10.1021/ml500525s
Coxsackievirus Coxsackievirus IC50 2101000.0 nM 10.1021/ml500525s
Coxsackievirus Coxsackievirus MIC 40.0 ug.mL-1 10.1021/jm00378a037
Coxsackievirus Coxsackievirus MIC 200.0 ug.mL-1 10.1021/jm00378a037
Coxsackievirus A16 Coxsackievirus A16 Activity nan None 10.1021/acs.jnatprod.8b00735
Coxsackievirus A16 Coxsackievirus A16 EC50 143610.0 nM 10.1021/acs.jnatprod.8b00735
Coxsackievirus A16 Coxsackievirus A16 IC50 4090000.0 nM 10.1016/j.bmc.2011.03.007
Coxsackievirus A16 Coxsackievirus A16 IC50 9622000.0 nM 10.1016/j.bmcl.2017.01.022
Coxsackievirus B1 Coxsackievirus B1 IC50 2375000.0 nM 10.1016/j.bmcl.2017.01.022
Coxsackievirus B1 Coxsackievirus B1 IC50 2375000.0 nM 10.1016/j.ejmech.2016.09.097
Coxsackievirus B1 Coxsackievirus B1 IZ 0.0 mm 10.1021/jm00199a015
Coxsackievirus B1 Coxsackievirus B1 PDD50 100.0 ug ml-1 10.1021/jm00199a015
Coxsackievirus B2 Coxsackievirus B2 EC50 100000.0 nM 10.1016/j.bmc.2009.05.020
Coxsackievirus B2 Coxsackievirus B2 EC50 100000.0 nM 10.1016/j.bmc.2010.02.037
Coxsackievirus B3 Coxsackievirus B3 Activity nan None 10.1021/jm060872x
Coxsackievirus B3 Coxsackievirus B3 EC50 0.04 ug.mL-1 10.1016/j.bmcl.2008.12.103
Coxsackievirus B3 Coxsackievirus B3 EC50 42.9 ug.mL-1 10.1016/j.ejmech.2017.08.057
Coxsackievirus B3 Coxsackievirus B3 EC50 64.09 ug.mL-1 10.1016/j.bmc.2006.09.066
Coxsackievirus B3 Coxsackievirus B3 EC50 92.45 ug.mL-1 10.1016/j.ejmech.2017.06.002
Coxsackievirus B3 Coxsackievirus B3 EC50 92.45 ug.mL-1 10.1016/s0960-894x(02)00182-8
Coxsackievirus B3 Coxsackievirus B3 EC50 236.4 ug.mL-1 10.1021/np020234r
Coxsackievirus B3 Coxsackievirus B3 IC50 20.3 ug.mL-1 10.1021/np800792d
Coxsackievirus B3 Coxsackievirus B3 IC50 292000.0 nM 10.1021/acs.jnatprod.6b00585
Coxsackievirus B3 Coxsackievirus B3 IC50 900000.0 nM 10.1021/np400638r
Coxsackievirus B3 Coxsackievirus B3 IC50 910000.0 nM 10.1016/j.bmcl.2011.08.002
Coxsackievirus B3 Coxsackievirus B3 IC50 1197580.0 nM 10.1021/acs.jnatprod.5b00325
Coxsackievirus B3 Coxsackievirus B3 IC50 1200000.0 nM 10.1021/np500951s
Coxsackievirus B3 Coxsackievirus B3 IC50 1576110.0 nM 10.1016/j.ejmech.2013.07.053
Coxsackievirus B3 Coxsackievirus B3 IC50 1690000.0 nM 10.1016/j.bmc.2011.03.007
Coxsackievirus B3 Coxsackievirus B3 IC50 nan None 10.1021/np050498o
Coxsackievirus B3 Coxsackievirus B3 Inhibition nan % 10.1016/j.ejmech.2017.08.057
Coxsackievirus B3 Coxsackievirus B3 Selectivity index 5.58 None 10.1016/s0960-894x(02)00182-8
Coxsackievirus B4 Coxsackievirus B4 Activity nan None 10.1016/j.ejmech.2011.11.021
Coxsackievirus B4 Coxsackievirus B4 EC50 14.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Coxsackievirus B4 Coxsackievirus B4 EC50 48.0 ug.mL-1 10.1021/jm061281+
Coxsackievirus B4 Coxsackievirus B4 EC50 50.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Coxsackievirus B4 Coxsackievirus B4 EC50 90.0 ug.mL-1 10.1021/jm0707166
Coxsackievirus B4 Coxsackievirus B4 EC50 146.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Coxsackievirus B4 Coxsackievirus B4 EC50 146.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Coxsackievirus B4 Coxsackievirus B4 EC50 146.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Coxsackievirus B4 Coxsackievirus B4 EC50 200.0 ug.mL-1 10.1021/jm0707166
Coxsackievirus B4 Coxsackievirus B4 EC50 240.0 ug.mL-1 10.1021/jm061281+
Coxsackievirus B4 Coxsackievirus B4 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Coxsackievirus B4 Coxsackievirus B4 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Coxsackievirus B4 Coxsackievirus B4 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Coxsackievirus B4 Coxsackievirus B4 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Coxsackievirus B4 Coxsackievirus B4 EC50 22000.0 nM 10.1016/j.ejmech.2013.06.036
Coxsackievirus B4 Coxsackievirus B4 EC50 28500.0 nM 10.1007/s00044-012-0184-x
Coxsackievirus B4 Coxsackievirus B4 EC50 30000.0 nM 10.1016/j.ejmech.2009.12.002
Coxsackievirus B4 Coxsackievirus B4 EC50 50000.0 nM 10.1021/jm801470b
Coxsackievirus B4 Coxsackievirus B4 EC50 61000.0 nM 10.1016/j.bmc.2015.12.008
Coxsackievirus B4 Coxsackievirus B4 EC50 69000.0 nM 10.1016/j.bmc.2011.04.016
Coxsackievirus B4 Coxsackievirus B4 EC50 73100.0 nM 10.1016/j.ejmech.2010.03.002
Coxsackievirus B4 Coxsackievirus B4 EC50 85000.0 nM 10.1016/j.ejmech.2017.04.070
Coxsackievirus B4 Coxsackievirus B4 EC50 146000.0 nM 10.1007/s00044-009-9248-y
Coxsackievirus B4 Coxsackievirus B4 EC50 146000.0 nM 10.1016/j.bmc.2012.03.004
Coxsackievirus B4 Coxsackievirus B4 EC50 146000.0 nM 10.1039/c1md00094b
Coxsackievirus B4 Coxsackievirus B4 EC50 150000.0 nM 10.1021/jm0614329
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1007/s00044-009-9248-y
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1007/s00044-012-0184-x
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.bmc.2011.04.016
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.bmc.2012.03.004
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.bmc.2015.04.079
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.bmc.2015.12.008
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.bmc.2018.05.034
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.ejmech.2009.12.002
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.ejmech.2012.03.007
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.ejmech.2013.06.036
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.ejmech.2015.08.008
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1016/j.ejmech.2017.04.070
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1021/jm801470b
Coxsackievirus B4 Coxsackievirus B4 EC50 250000.0 nM 10.1039/c1md00094b
Coxsackievirus B4 Coxsackievirus B4 EC50 500000.0 nM 10.1021/jm060030y
Coxsackievirus B4 Coxsackievirus B4 IC50 20.0 ug.mL-1 10.1021/jm0701472
Coxsackievirus B4 Coxsackievirus B4 IC50 500000.0 nM 10.1016/j.ejmech.2016.09.097
Coxsackievirus B4 Coxsackievirus B4 IC50 40948000.0 nM 10.1016/j.bmcl.2017.01.022
Coxsackievirus B4 Coxsackievirus B4 MIC 20.0 ug.mL-1 10.1021/jm00369a010
Coxsackievirus B4 Coxsackievirus B4 MIC 20.0 ug.mL-1 10.1021/jm00373a020
Coxsackievirus B4 Coxsackievirus B4 MIC 40.0 ug.mL-1 10.1021/jm00102a010
Coxsackievirus B4 Coxsackievirus B4 MIC 70.0 ug.mL-1 10.1021/jm00102a010
Coxsackievirus B4 Coxsackievirus B4 MIC 100.0 ug.mL-1 10.1021/jm00128a011
Coxsackievirus B4 Coxsackievirus B4 MIC 200.0 ug.mL-1 10.1021/jm00373a020
Coxsackievirus B4 Coxsackievirus B4 MIC 240.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Coxsackievirus B4 Coxsackievirus B4 MIC 400.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Coxsackievirus B4 Coxsackievirus B4 MIC 400.0 ug.mL-1 10.1021/jm00369a010
Coxsackievirus B4 Coxsackievirus B4 MIC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Coxsackievirus B4 Coxsackievirus B4 MIC 250000.0 nM 10.1021/jm070324z
Coxsackievirus B4 Coxsackievirus B4 MIC 500000.0 nM 10.1016/j.bmc.2006.10.046
Coxsackievirus B4 Coxsackievirus B4 MIC 500000.0 nM 10.1021/np060435l
Coxsackievirus B4 Coxsackievirus B4 MIC50 9.6 ug.mL-1 10.1021/jm050772b
Coxsackievirus B4 Coxsackievirus B4 MIC50 10.0 ug.mL-1 10.1021/jm950891z
Coxsackievirus B4 Coxsackievirus B4 MIC50 40.0 ug.mL-1 10.1021/jm00220a027
Coxsackievirus B4 Coxsackievirus B4 MIC50 40.0 ug.mL-1 10.1021/jm00386a007
Coxsackievirus B4 Coxsackievirus B4 MIC50 70.0 ug.mL-1 10.1021/jm00386a007
Coxsackievirus B4 Coxsackievirus B4 MIC50 150.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Coxsackievirus B4 Coxsackievirus B4 MIC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Coxsackievirus B4 Coxsackievirus B4 MIC50 400.0 ug.mL-1 10.1021/jm050772b
Coxsackievirus B4 Coxsackievirus B4 MIC50 400.0 ug.mL-1 10.1021/jm950891z
Coxsackievirus B5 Coxsackievirus B5 EC50 22.3 ug.mL-1 10.1016/j.bmcl.2013.07.023
Coxsackievirus B5 Coxsackievirus B5 EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Coxsackievirus B5 Coxsackievirus B5 EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
Coxsackievirus B5 Coxsackievirus B5 IC50 3316000.0 nM 10.1016/j.bmcl.2017.01.022
Coxsackievirus B5 Coxsackievirus B5 IC50 3316000.0 nM 10.1016/j.ejmech.2016.09.097
Coxsackievirus B6 Coxsackievirus B6 IC50 909960.0 nM 10.1016/j.ejmech.2013.07.053
Coxsackievirus B6 Coxsackievirus B6 IC50 910000.0 nM 10.1016/j.bmc.2011.03.007
Cricetulus griseus CHO-K1 IC50 50000.0 nM 10.1016/0960-894X(96)00216-8
Dengue virus Dengue virus EC50 49.0 ug.mL-1 10.1021/jm900652e
Dengue virus Dengue virus EC50 11900.0 nM 10.1021/acsmedchemlett.8b00583
Dengue virus Dengue virus EC50 49000.0 nM 10.1016/j.ejmech.2014.10.010
Dengue virus Dengue virus Inhibition 75.0 % 10.1021/acsmedchemlett.1c00515
dengue virus type 1 dengue virus type 1 IC50 6660.0 nM 10.1016/j.bmc.2019.04.015
dengue virus type 2 dengue virus type 2 Activity 8.3 PbU 10.1016/j.ejmech.2015.12.030
dengue virus type 2 dengue virus type 2 Activity nan None 10.1016/j.ejmech.2015.11.009
dengue virus type 2 dengue virus type 2 EC 5.0 ug ml-1 10.1021/acs.jnatprod.2c00464
dengue virus type 2 dengue virus type 2 EC 40.0 ug ml-1 10.1021/acs.jnatprod.2c00464
dengue virus type 2 dengue virus type 2 EC50 1160.0 nM 10.1016/j.bmcl.2023.129174
dengue virus type 2 dengue virus type 2 EC50 11900.0 nM 10.1021/acsmedchemlett.8b00583
dengue virus type 2 dengue virus type 2 EC50 12600.0 nM 10.1021/np5002829
dengue virus type 2 dengue virus type 2 EC50 13500.0 nM 10.1016/j.ejmech.2015.11.009
dengue virus type 2 dengue virus type 2 EC50 40000.0 nM 10.1021/acs.jmedchem.5b01653
dengue virus type 2 dengue virus type 2 EC50 42000.0 nM 10.1021/acs.jmedchem.5b00108
dengue virus type 2 dengue virus type 2 EC50 47900.0 nM 10.1016/j.bmcl.2015.02.059
dengue virus type 2 dengue virus type 2 EC50 nan None 10.1016/j.bmc.2015.09.035
dengue virus type 2 dengue virus type 2 EC50 nan None 10.1016/j.ejmech.2015.11.009
dengue virus type 2 dengue virus type 2 IC50 4000.0 nM 10.1016/j.ejmech.2021.113683
dengue virus type 2 dengue virus type 2 IC50 4000.0 nM 10.1021/acs.jmedchem.0c01039
dengue virus type 2 dengue virus type 2 IC50 4000.0 nM 10.1021/acsmedchemlett.9b00681
dengue virus type 2 dengue virus type 2 IC50 4100.0 nM 10.1016/j.ejmech.2021.113683
dengue virus type 2 dengue virus type 2 IC50 7600.0 nM 10.1016/j.ejmech.2021.113683
dengue virus type 2 dengue virus type 2 IC50 12610.0 nM 10.1016/j.ejmech.2014.03.074
dengue virus type 2 dengue virus type 2 IC50 12610.0 nM 10.1016/j.ejmech.2017.10.001
dengue virus type 2 dengue virus type 2 Inhibition 10.14 % 10.1016/j.ejmech.2017.10.001
dengue virus type 2 dengue virus type 2 Inhibition 32.03 % 10.1016/j.ejmech.2014.03.074
dengue virus type 2 dengue virus type 2 Inhibition 32.53 % 10.1016/j.ejmech.2017.10.001
dengue virus type 2 dengue virus type 2 Inhibition 50.0 % 10.1021/acs.jnatprod.2c00464
dengue virus type 2 dengue virus type 2 Inhibition 67.47 % 10.1016/j.ejmech.2014.03.074
dengue virus type 2 dengue virus type 2 Inhibition 75.0 % 10.1021/acs.jnatprod.2c00464
dengue virus type 2 dengue virus type 2 MNTD 123.0 uM 10.1016/j.ejmech.2015.11.009
Encephalomyocarditis virus Encephalomyocarditis virus EC50 0.02 ug.mL-1 10.1016/j.bmcl.2008.12.103
Encephalomyocarditis virus Encephalomyocarditis virus EC50 23.45 ug.mL-1 10.1016/j.bmc.2006.09.066
Encephalomyocarditis virus Encephalomyocarditis virus EC50 27.2 ug.mL-1 10.1021/np020234r
Enterococcus faecalis Enterococcus faecalis MIC nan None 10.1021/jm00199a015
Enterovirus Enterovirus Activity nan None 10.1021/jm00126a027
Enterovirus Enterovirus EC50 49.2 ug.mL-1 10.1016/j.bmcl.2013.07.023
Enterovirus Enterovirus Inhibition nan % 10.1021/jm00207a009
Enterovirus A71 Enterovirus A71 Activity 5.0 % 10.1016/j.bmcl.2012.01.102
Enterovirus A71 Enterovirus A71 Activity 15.0 % 10.1016/j.bmcl.2015.06.097
Enterovirus A71 Enterovirus A71 EC50 32.5 ug.mL-1 10.1016/j.ejmech.2017.08.057
Enterovirus A71 Enterovirus A71 IC50 60.0 ug.mL-1 10.1016/j.bmcl.2012.01.102
Enterovirus A71 Enterovirus A71 IC50 13300.0 nM 10.1016/j.ejmech.2020.112790
Enterovirus A71 Enterovirus A71 IC50 2119000.0 nM 10.1016/j.bmcl.2011.08.002
Enterovirus A71 Enterovirus A71 IC50 2340000.0 nM 10.1016/j.bmc.2011.03.007
Enterovirus A71 Enterovirus A71 Inhibition nan % 10.1016/j.ejmech.2017.08.057
Enterovirus A71 Genome polyprotein EC50 100000.0 nM 10.1021/acsmedchemlett.7b00188
Enterovirus C Enterovirus C Activity 4.0 % 10.1021/jm7009952
Enterovirus C Enterovirus C Activity 40.0 % 10.1021/jm7009952
Enterovirus C Enterovirus C Activity nan None 10.1021/jm060872x
Enterovirus C Enterovirus C MIC 20.0 ug.mL-1 10.1021/jm00378a037
Enterovirus C Enterovirus C MIC50 20.0 ug.mL-1 10.1021/jm950891z
Enterovirus C Enterovirus C PFU 150.0 None 10.1021/jm100593s
Enterovirus C Enterovirus C PFU 250.0 None 10.1021/jm100593s
Enterovirus E Enterovirus E Activity nan None 10.1016/j.ejmech.2021.113738
Enterovirus E Enterovirus E EC50 102500.0 nM 10.1016/j.ejmech.2021.113738
Escherichia coli Escherichia coli MIC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Felid alphaherpesvirus 1 Felid alphaherpesvirus 1 Activity nan None 10.1016/j.ejmech.2011.11.021
Feline coronavirus Feline coronavirus Activity nan None 10.1016/j.ejmech.2011.11.021
Feline coronavirus Feline coronavirus EC50 nan None 10.1016/j.bmc.2011.04.016
Gallus gallus Fibroblast CC50 200000.0 nM 10.1021/acs.jmedchem.8b01065
H2N2 subtype H2N2 subtype IC50 13800.0 nM 10.1016/j.bmc.2008.11.075
H3N2 subtype H3N2 subtype EC50 5900.0 nM 10.1016/j.ejmech.2018.08.058
H3N2 subtype H3N2 subtype EC50 6000.0 nM 10.1016/j.bmcl.2012.09.079
H3N2 subtype H3N2 subtype EC50 6000.0 nM 10.1021/jm900950d
H3N2 subtype H3N2 subtype EC50 7000.0 nM 10.1021/ml300279b
H3N2 subtype H3N2 subtype EC50 7700.0 nM 10.1021/ml300279b
H3N2 subtype H3N2 subtype EC50 8700.0 nM 10.1016/j.ejmech.2010.08.009
H3N2 subtype H3N2 subtype EC50 8900.0 nM 10.1016/j.ejmech.2012.10.030
H3N2 subtype H3N2 subtype EC50 9000.0 nM 10.1021/jm900950d
H3N2 subtype H3N2 subtype EC50 13000.0 nM 10.1016/j.ejmech.2018.08.058
H3N2 subtype H3N2 subtype EC90 4.6 uM 10.1021/jm401340p
H3N2 subtype H3N2 subtype EC99 11.0 uM 10.1021/jm401340p
H3N2 subtype H3N2 subtype IC50 99600.0 nM 10.1016/j.bmcl.2018.07.029
H5N1 subtype H5N1 subtype EC50 4300.0 nM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC50 9400.0 nM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC50 23600.0 nM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC50 27400.0 nM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC50 32500.0 nM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC50 35400.0 nM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC90 16.8 uM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC90 20.3 uM 10.1016/j.bmcl.2010.02.074
H5N1 subtype H5N1 subtype EC90 43.6 uM 10.1016/j.bmcl.2010.02.074
Hepacivirus hominis Hepatitis C virus Activity 50.0 % 10.1016/j.bmcl.2015.06.006
Hepacivirus hominis Hepatitis C virus Activity 80.0 % 10.1016/j.bmc.2022.116858
Hepacivirus hominis Hepatitis C virus Activity 89.0 % 10.1016/j.bmcl.2005.09.015
Hepacivirus hominis Hepatitis C virus Activity 89.0 % 10.1016/j.bmcl.2007.01.085
Hepacivirus hominis Hepatitis C virus Activity 89.0 % 10.1016/j.bmcl.2013.12.121
Hepacivirus hominis Hepatitis C virus Activity nan None 10.1016/j.bmc.2011.10.058
Hepacivirus hominis Hepatitis C virus Activity nan None 10.1016/j.bmc.2022.116858
Hepacivirus hominis Hepatitis C virus EC50 7.0 ug.mL-1 10.1016/j.bmcl.2008.04.026
Hepacivirus hominis Hepatitis C virus EC50 20.0 ug.mL-1 10.1016/j.bmcl.2012.08.042
Hepacivirus hominis Hepatitis C virus EC50 5600.0 nM 10.1016/j.bmc.2014.08.024
Hepacivirus hominis Hepatitis C virus EC50 8700.0 nM 10.1016/j.bmcl.2014.07.019
Hepacivirus hominis Hepatitis C virus EC50 14000.0 nM 10.1016/j.bmc.2011.10.058
Hepacivirus hominis Hepatitis C virus EC50 16300.0 nM 10.1021/acs.jmedchem.5b01064
Hepacivirus hominis Hepatitis C virus EC50 17600.0 nM 10.1021/jm901741p
Hepacivirus hominis Hepatitis C virus EC50 22000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 28700.0 nM 10.1021/jm800927r
Hepacivirus hominis Hepatitis C virus EC50 30400.0 nM 10.1016/j.bmcl.2015.09.029
Hepacivirus hominis Hepatitis C virus EC50 33000.0 nM 10.1021/jm800927r
Hepacivirus hominis Hepatitis C virus EC50 33000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 33500.0 nM 10.1016/j.bmcl.2015.09.029
Hepacivirus hominis Hepatitis C virus EC50 36000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 41000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 42000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 43000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 47000.0 nM 10.1128/aac.00078-08
Hepacivirus hominis Hepatitis C virus EC50 52000.0 nM 10.1128/aac.00078-08
Hepacivirus hominis Hepatitis C virus EC50 54800.0 nM 10.1016/j.bmc.2007.08.025
Hepacivirus hominis Hepatitis C virus EC50 58000.0 nM 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus EC50 69000.0 nM 10.1128/aac.00078-08
Hepacivirus hominis Hepatitis C virus EC50 81900.0 nM 10.1016/j.bmcl.2014.01.024
Hepacivirus hominis Hepatitis C virus EC50 84000.0 nM 10.1021/jm800927r
Hepacivirus hominis Hepatitis C virus EC50 87000.0 nM 10.1016/j.bmc.2010.02.015
Hepacivirus hominis Hepatitis C virus EC50 100000.0 nM 10.1021/jm058200e
Hepacivirus hominis Hepatitis C virus EC50 120000.0 nM 10.1016/j.bmc.2010.05.066
Hepacivirus hominis Hepatitis C virus EC90 100.0 uM 10.1021/jm058200e
Hepacivirus hominis Hepatitis C virus EC90 107.0 uM 10.1128/aac.00078-08
Hepacivirus hominis Hepatitis C virus EC90 122.0 uM 10.1128/aac.00078-08
Hepacivirus hominis Hepatitis C virus EC90 123.0 uM 10.1128/aac.00078-08
Hepacivirus hominis Hepatitis C virus ED50 5.6 uM 10.1016/j.bmcl.2013.07.005
Hepacivirus hominis Hepatitis C virus FC 0.4 None 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus FC 0.6 None 10.1074/jbc.m610207200
Hepacivirus hominis Hepatitis C virus FC 0.6 None 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus FC 0.7 None 10.1074/jbc.m610207200
Hepacivirus hominis Hepatitis C virus FC 0.7 None 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus FC 0.8 None 10.1128/aac.00863-07
Hepacivirus hominis Hepatitis C virus IC50 12.5 ug.mL-1 10.1016/j.bmcl.2017.11.029
Hepacivirus hominis Hepatitis C virus IC50 40.0 nM 10.1016/j.bmcl.2016.05.072
Hepacivirus hominis Hepatitis C virus IC50 13160.0 nM 10.1016/j.ejmech.2017.12.006
Hepacivirus hominis Hepatitis C virus IC50 21780.0 nM 10.1016/j.bmc.2022.116858
Hepacivirus hominis Hepatitis C virus IC50 32000.0 nM 10.1074/jbc.m610207200
Hepacivirus hominis Hepatitis C virus IC50 37000.0 nM 10.1074/jbc.m610207200
Hepacivirus hominis Hepatitis C virus IC50 39000.0 nM 10.1074/jbc.m610207200
Hepacivirus hominis Hepatitis C virus IC50 58000.0 nM 10.1074/jbc.m610207200
Hepacivirus hominis Hepatitis C virus IC50 nan None 10.1016/j.ejmech.2013.07.053
Hepacivirus hominis Hepatitis C virus Inhibition 31.2 % 10.1016/j.ejmech.2017.12.006
Hepacivirus hominis Hepatitis C virus Inhibition 32.0 % 10.1016/j.bmcl.2014.01.024
Hepacivirus hominis Hepatitis C virus Inhibition 35.0 % 10.1016/j.bmcl.2012.08.042
Hepacivirus hominis Hepatitis C virus Inhibition 44.0 % 10.1016/j.bmc.2012.05.066
Hepacivirus hominis Hepatitis C virus Inhibition 50.0 % 10.1016/j.bmc.2010.08.048
Hepacivirus hominis Hepatitis C virus Inhibition 50.0 % 10.1016/j.bmcl.2012.08.042
Hepacivirus hominis Hepatitis C virus Inhibition 50.0 % 10.1016/j.bmcl.2014.01.024
Hepacivirus hominis Hepatitis C virus Inhibition 65.74 % 10.1016/j.ejmech.2017.12.006
Hepacivirus hominis Hepatitis C virus Inhibition nan % 10.1016/j.bmcl.2014.07.019
Hepacivirus hominis Hepatitis C virus Inhibition nan % 10.1128/aac.00939-08
Hepacivirus hominis Hepatitis C virus MIC 16.15 ug.mL-1 10.1016/j.bmc.2009.10.012
Hepacivirus hominis Hepatitis C virus MIC 16.15 ug.mL-1 10.1016/j.ejmech.2009.10.033
Hepacivirus hominis Hepatitis C virus MIC 77.89 ug.mL-1 10.1016/j.ejmech.2009.10.033
Homo sapiens A-431 IC50 3180.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens A-431 Inhibition 70.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens A549 CC20 409.84 uM 10.1016/j.ejmech.2021.113738
Homo sapiens A549 CC50 50000.0 nM 10.1016/j.ejmech.2021.113683
Homo sapiens A549 CC50 50000.0 nM 10.1016/j.ejmech.2022.114275
Homo sapiens A549 CC50 129650.0 nM 10.1016/j.bmcl.2020.127518
Homo sapiens A549 CC50 307000.0 nM 10.1016/j.bmcl.2018.12.063
Homo sapiens A549 CC50 7611100.0 nM 10.1016/j.ejmech.2021.113738
Homo sapiens A549 IC50 nan None 10.1021/acs.jmedchem.8b01403
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens ACHN IC50 100000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens Adenosine A1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki 7410.0 nM 10.1021/acs.jmedchem.8b01662
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Inhibition 23.0 % 10.1021/acs.jmedchem.8b01662
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Inhibition 16.0 % 10.1021/acs.jmedchem.8b01662
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Adenosine kinase Activity 203.0 nmol/mg.hr 10.1016/j.bmcl.2007.03.018
Homo sapiens Adenosylhomocysteinase Activity 2.2 10^10/M 10.1016/j.bmc.2007.08.029
Homo sapiens Adenosylhomocysteinase Activity nan None 10.1016/j.bmc.2007.08.029
Homo sapiens Adenosylhomocysteinase Fluorescence intensity 182369.0 None 10.1016/j.bmc.2007.08.029
Homo sapiens Adenosylhomocysteinase Kinact 1.5 10^-4/s 10.1016/j.bmc.2007.08.029
Homo sapiens Adenosylhomocysteinase Kinact 266.0 uM 10.1016/j.bmc.2007.08.029
Homo sapiens Adenosylhomocysteinase KR 407.0 uM 10.1016/j.bmc.2007.08.029
Homo sapiens Adenosylhomocysteinase Ratio 0.56 /M/s 10.1016/j.bmc.2007.08.029
Homo sapiens Adrenergic receptor beta Activity -4.88 None 10.1016/S0960-894X(97)00046-2
Homo sapiens Aldehyde dehydrogenase 1A1 Potency 25118.9 nM None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Alpha-galactosidase A Potency 50118.7 nM None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Ataxin-2 Potency 31622.8 nM None
Homo sapiens ATH-8 cell line MIC 400000.0 nM 10.1021/jm00159a001
Homo sapiens ATH-8 cell line SI 0.3 None 10.1021/jm00159a001
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile acid receptor FXR Potency 31622.8 nM None
Homo sapiens Bile salt export pump AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens BJ CC50 100000.0 nM 10.1021/acs.jmedchem.7b00180
Homo sapiens Bradykinin B2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens C8166 IC50 100000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens Caco-2 CC50 nan None 10.1016/j.ejmech.2021.113683
Homo sapiens Caco-2 IC50 34500.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens Caco-2 Inhibition 60.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Calu-3 CC50 nan None 10.1016/j.ejmech.2021.113683
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens CCRF-CEM CC50 nan None 10.1016/j.bmc.2011.04.016
Homo sapiens CCRF-CEM IC50 19.0 ug.mL-1 10.1021/jm00075a030
Homo sapiens CCRF-CEM IC50 19000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens CCRF-CEM IC50 63000.0 nM 10.1016/j.bmc.2012.01.054
Homo sapiens CCRF-SB IC50 100000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens Cellular tumor antigen p53 Potency 31622.8 nM None
Homo sapiens Cerebroside-sulfatase Potency 16944.1 nM None
Homo sapiens Cholecystokinin A receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Chromobox protein homolog 1 Potency 89125.1 nM None
Homo sapiens Cyclin-dependent kinase 2 Inhibition nan % 10.1021/jm100941j
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 3A4 IC50 nan None None
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Cytochrome P450 3A4 Potency 794.3 nM None
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens DNA topoisomerase I IC50 65880.0 nM 10.1039/C2MD20286G
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens DU-145 IC50 100000.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens DU-145 Inhibition 50.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens E6SM CC50 400.0 ug.mL-1 10.1021/jm9507901
Homo sapiens E6SM EC50 5.0 nM 10.1021/jm0108350
Homo sapiens E6SM EC50 40000.0 nM 10.1021/jm0108350
Homo sapiens E6SM EC50 65000.0 nM 10.1021/jm0108350
Homo sapiens E6SM EC50 128000.0 nM 10.1021/jm980163m
Homo sapiens E6SM EC50 192000.0 nM 10.1021/jm980163m
Homo sapiens E6SM EC50 320000.0 nM 10.1021/jm0108350
Homo sapiens E6SM EC50 960000.0 nM 10.1021/jm980163m
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1021/jm00072a013
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1021/jm0108404
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1021/jm025569k
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1021/jm061281+
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1021/jm0701472
Homo sapiens E6SM MCC 400.0 ug.mL-1 10.1021/jm100093p
Homo sapiens E6SM MIC 16.0 ug.mL-1 10.1021/jm0108404
Homo sapiens E6SM MIC 20.0 ug.mL-1 10.1021/jm00072a013
Homo sapiens E6SM MIC 40.0 ug.mL-1 10.1021/jm00096a012
Homo sapiens E6SM MIC 48.0 ug.mL-1 10.1021/jm0108404
Homo sapiens E6SM MIC 50.0 ug.mL-1 10.1021/jm960500w
Homo sapiens E6SM MIC 60.0 ug.mL-1 10.1021/jm960500w
Homo sapiens E6SM MIC 70.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens E6SM MIC 70.0 ug.mL-1 10.1021/jm00072a013
Homo sapiens E6SM MIC 70.0 ug.mL-1 10.1021/jm00096a012
Homo sapiens E6SM MIC 80.0 ug.mL-1 10.1021/jm960500w
Homo sapiens E6SM MIC 90.0 ug.mL-1 10.1021/jm960500w
Homo sapiens E6SM MIC 100.0 ug.mL-1 10.1021/jm960500w
Homo sapiens E6SM MIC 150.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens E6SM MIC 150.0 ug.mL-1 10.1021/jm960500w
Homo sapiens E6SM MIC 240.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Homo sapiens E6SM MIC 240.0 ug.mL-1 10.1021/jm0108404
Homo sapiens E6SM MIC 300.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens E6SM MIC 300.0 ug.mL-1 10.1021/jm00072a013
Homo sapiens E6SM MIC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Homo sapiens E6SM MIC 400.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens E6SM MIC 400.0 ug.mL-1 10.1021/jm00045a025
Homo sapiens E6SM MIC 400.0 ug.mL-1 10.1021/jm00096a012
Homo sapiens E6SM MIC 500000.0 nM 10.1016/j.bmc.2006.10.046
Homo sapiens E6SM MIC 1600000.0 nM 10.1021/jm0108350
Homo sapiens E6SM MIC 1600000.0 nM 10.1021/jm980163m
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens Geminin Potency 183.6 nM None
Homo sapiens Ghrelin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens Glycogen synthase kinase-3 beta IC50 nan None 10.1021/jm100941j
Homo sapiens Glycogen synthase kinase-3 beta Inhibition 33.3 % 10.1021/jm100941j
Homo sapiens HCT-116 Activity nan None 10.1021/acsmedchemlett.2c00196
Homo sapiens HCT-116 EC50 100000.0 nM 10.1021/acsmedchemlett.2c00196
Homo sapiens HEK293 CC50 250000.0 nM 10.1021/jm401560v
Homo sapiens HEK293 EC50 100000.0 nM 10.1021/acsmedchemlett.2c00196
Homo sapiens HEK293 Potency 23099.9 nM None
Homo sapiens HEK-293T CC50 100000.0 nM 10.1016/j.bmcl.2022.128681
Homo sapiens HEK-293T CC50 100000.0 nM 10.1016/j.ejmech.2019.111861
Homo sapiens HEK-293T CC50 100000.0 nM 10.1016/j.ejmech.2020.112706
Homo sapiens HEK-293T CC50 100000.0 nM 10.1021/acs.jmedchem.7b00180
Homo sapiens HEK-293T CC50 200000.0 nM 10.1021/acsmedchemlett.5b00109
Homo sapiens HEK-293T CC50 205000.0 nM 10.1016/j.bmcl.2017.03.015
Homo sapiens HEK-293T CC50 250000.0 nM 10.1016/j.ejmech.2018.08.032
Homo sapiens HEK-293T CC50 250000.0 nM 10.1021/acs.jmedchem.5b00012
Homo sapiens HEK-293T CC50 250000.0 nM 10.1021/jm500300r
Homo sapiens HEK-293T CC50 nan None 10.1016/j.bmcl.2021.127926
Homo sapiens HEK-293T IC50 100000.0 nM 10.1016/j.ejmech.2021.113208
Homo sapiens HEK-293T Inhibition 0.0 % 10.1016/j.bmcl.2017.03.015
Homo sapiens HEL Activity 250.0 ug ml-1 10.1016/j.ejmech.2010.07.058
Homo sapiens HEL CC50 250000.0 nM 10.1016/j.ejmech.2009.12.002
Homo sapiens HEL CC50 250000.0 nM 10.1016/j.ejmech.2010.12.017
Homo sapiens HEL CC50 500000.0 nM 10.1021/jm060030y
Homo sapiens HEL MCC 200.0 ug.mL-1 10.1021/jm0707166
Homo sapiens HEL MCC 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Homo sapiens HEL MCC 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Homo sapiens HEL MCC 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Homo sapiens HEL MCC 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Homo sapiens HEL MCC 400.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Homo sapiens HEL MCC 400.0 ug.mL-1 10.1021/jm050772b
Homo sapiens HEL MCC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Homo sapiens HEL MCC 100000.0 nM 10.1016/j.bmc.2010.02.015
Homo sapiens HEL MCC 250000.0 nM 10.1007/s00044-009-9248-y
Homo sapiens HEL MCC 250000.0 nM 10.1016/j.bmc.2008.08.041
Homo sapiens HEL MCC 250000.0 nM 10.1016/j.bmc.2012.03.004
Homo sapiens HEL MCC 250000.0 nM 10.1016/j.bmc.2015.12.008
Homo sapiens HEL MCC 250000.0 nM 10.1016/j.ejmech.2010.12.017
Homo sapiens HEL MCC 250000.0 nM 10.1016/j.ejmech.2016.10.002
Homo sapiens HEL MCC 250000.0 nM 10.1021/jm801470b
Homo sapiens HEL MCC 250000.0 nM 10.1039/c1md00094b
Homo sapiens HEL 299 CC50 250000.0 nM 10.1039/d3md00055a
Homo sapiens HEL 299 IC50 45000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens HeLa Activity 70.0 % 10.1021/jm060872x
Homo sapiens HeLa Activity 250.0 ug ml-1 10.1016/j.ejmech.2010.07.058
Homo sapiens HeLa CC50 200.0 ug.mL-1 10.1021/jm9507901
Homo sapiens HeLa CC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.03.002
Homo sapiens HeLa CC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Homo sapiens HeLa CC50 300.0 ug.mL-1 10.1016/j.bmc.2006.09.066
Homo sapiens HeLa CC50 300.0 ug.mL-1 10.1016/s0960-894x(03)00730-3
Homo sapiens HeLa CC50 300.0 ug.mL-1 10.1021/np020234r
Homo sapiens HeLa CC50 426.0 ug.mL-1 10.1021/np800792d
Homo sapiens HeLa CC50 500.0 ug.mL-1 10.1016/j.bmcl.2013.07.023
Homo sapiens HeLa CC50 250000.0 nM 10.1007/s00044-012-0184-x
Homo sapiens HeLa CC50 250000.0 nM 10.1016/j.bmc.2011.04.016
Homo sapiens HeLa CC50 250000.0 nM 10.1016/j.ejmech.2009.12.002
Homo sapiens HeLa CC50 500000.0 nM 10.1021/jm060030y
Homo sapiens HeLa EC50 14.41 ug.mL-1 10.1016/s0960-894x(03)00730-3
Homo sapiens HeLa EC50 20.94 ug.mL-1 10.1016/s0960-894x(03)00730-3
Homo sapiens HeLa EC50 181.36 ug.mL-1 10.1016/s0960-894x(03)00730-3
Homo sapiens HeLa EC50 1500.0 nM 10.1021/jm0108350
Homo sapiens HeLa EC50 192000.0 nM 10.1021/jm980163m
Homo sapiens HeLa EC50 320000.0 nM 10.1021/jm0108350
Homo sapiens HeLa EC50 320000.0 nM 10.1021/jm980163m
Homo sapiens HeLa EC50 1000000.0 nM 10.1021/jm0108350
Homo sapiens HeLa IC50 4.0 ug.mL-1 10.1021/jm00075a030
Homo sapiens HeLa IC50 14.0 ug.mL-1 10.1021/jm00075a030
Homo sapiens HeLa IC50 70.0 ug.mL-1 10.1021/jm00075a030
Homo sapiens HeLa IC50 400.0 ug.mL-1 10.1021/jm00075a030
Homo sapiens HeLa IC50 11400.0 nM 10.1021/jm00018a015
Homo sapiens HeLa MCC 20.0 ug.mL-1 10.1021/jm00152a007
Homo sapiens HeLa MCC 70.0 ug.mL-1 10.1021/jm00152a007
Homo sapiens HeLa MCC 100.0 ug.mL-1 10.1021/jm00199a015
Homo sapiens HeLa MCC 200.0 ug.mL-1 10.1021/jm00125a024
Homo sapiens HeLa MCC 200.0 ug.mL-1 10.1021/jm00128a011
Homo sapiens HeLa MCC 200.0 ug.mL-1 10.1021/jm00389a005
Homo sapiens HeLa MCC 200.0 ug.mL-1 10.1021/jm0707166
Homo sapiens HeLa MCC 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Homo sapiens HeLa MCC 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Homo sapiens HeLa MCC 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Homo sapiens HeLa MCC 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1016/j.bmcl.2005.01.047
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1021/jm00095a019
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1021/jm00152a007
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1021/jm00369a010
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1021/jm050772b
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1021/jm061281+
Homo sapiens HeLa MCC 400.0 ug.mL-1 10.1021/jm100093p
Homo sapiens HeLa MCC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Homo sapiens HeLa MCC 100000.0 nM 10.1016/j.bmc.2010.02.015
Homo sapiens HeLa MCC 250000.0 nM 10.1007/s00044-009-9248-y
Homo sapiens HeLa MCC 250000.0 nM 10.1007/s00044-012-0184-x
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.bmc.2008.08.041
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.bmc.2012.03.004
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.bmc.2015.12.008
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.bmc.2018.05.034
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2010.03.002
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2012.03.007
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2013.05.046
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2013.06.036
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2015.06.024
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2017.04.070
Homo sapiens HeLa MCC 250000.0 nM 10.1016/j.ejmech.2018.05.059
Homo sapiens HeLa MCC 250000.0 nM 10.1021/jm801470b
Homo sapiens HeLa MCC 250000.0 nM 10.1039/c1md00094b
Homo sapiens HeLa MIC 3.0 ug.mL-1 10.1021/jm00095a019
Homo sapiens HeLa MIC 4.0 ug.mL-1 10.1021/jm960770e
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1021/jm00095a019
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1021/jm00096a012
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1021/jm00125a024
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1021/jm00128a011
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1021/jm00167a011
Homo sapiens HeLa MIC 20.0 ug.mL-1 10.1021/jm00389a005
Homo sapiens HeLa MIC 48.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1016/S0960-894X(01)80538-2
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1021/jm00095a019
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1021/jm00096a012
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1021/jm00125a024
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1021/jm00128a011
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1021/jm00389a005
Homo sapiens HeLa MIC 70.0 ug.mL-1 10.1021/jm960770e
Homo sapiens HeLa MIC 200.0 ug.mL-1 10.1021/jm960770e
Homo sapiens HeLa MIC 240.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Homo sapiens HeLa MIC 500000.0 nM 10.1021/np060435l
Homo sapiens HeLa MIC 1600000.0 nM 10.1021/jm0108350
Homo sapiens HeLa MIC 1600000.0 nM 10.1021/jm980163m
Homo sapiens HeLa MIC50 1.92 ug.mL-1 10.1016/j.bmcl.2005.01.047
Homo sapiens HeLa MIC50 2.8 ug.mL-1 10.1021/jm00044a010
Homo sapiens HeLa MIC50 16.0 ug.mL-1 10.1016/j.bmcl.2005.01.047
Homo sapiens HeLa MIC50 48.0 ug.mL-1 10.1016/j.bmcl.2005.01.047
Homo sapiens HeLa MIC50 70.0 ug.mL-1 10.1021/jm00044a010
Homo sapiens HeLa MIC50 200.0 ug.mL-1 10.1021/jm00044a010
Homo sapiens HeLa MIC50 400.0 ug.mL-1 10.1021/jm950891z
Homo sapiens HeLa MTC 400.0 ug ml-1 10.1021/jm00386a007
Homo sapiens HeLa MTC 819.6 uM 10.1021/jm00018a015
Homo sapiens HEp-2 Activity 90.0 % 10.1021/jm300612z
Homo sapiens HEp-2 CC50 571.6 ug.mL-1 10.1016/j.ejmech.2017.08.057
Homo sapiens HEp-2 CC50 95000.0 nM 10.1021/acs.jnatprod.2c00766
Homo sapiens HEp-2 CC50 113900.0 nM 10.1021/jm300612z
Homo sapiens HEp-2 CC50 250000.0 nM 10.1016/j.ejmech.2021.113467
Homo sapiens HEp-2 CC50 273800.0 nM 10.1016/j.ejmech.2019.111861
Homo sapiens HEp-2 CC50 418210.0 nM 10.1016/j.ejmech.2021.113684
Homo sapiens HEp-2 CC50 1000000.0 nM 10.1021/acs.jnatprod.2c00322
Homo sapiens HEp-2 CC50 3039670.0 nM 10.1016/j.ejmech.2021.113208
Homo sapiens HEp-2 Virus rating 1.2 None 10.1021/jm00353a012
Homo sapiens HEp-2 Virus rating 1.7 None 10.1021/jm00353a012
Homo sapiens HepG2 Activity 100.0 % 10.1021/acsmedchemlett.9b00405
Homo sapiens HepG2 CC50 500.0 ug.mL-1 10.1016/j.bmcl.2013.07.023
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase 6 Inhibition -7.83 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -3.36 % 10.6019/CHEMBL4808148
Homo sapiens HL-60 ID50 67.0 uM 10.1021/jm00163a054
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens Activity 0.33 % 10.1016/j.ejmech.2009.11.034
Homo sapiens Homo sapiens CL 5.2 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 1.7 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 7.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 64.0 % 10.1016/j.bmc.2007.08.060
Homo sapiens Homo sapiens MCC 400.0 ug.mL-1 10.1021/jm00128a011
Homo sapiens HT-29 IC50 nan nM 10.1016/0960-894X(96)00216-8
Homo sapiens Huh-5-2 CC50 21.0 ug.mL-1 10.1016/j.bmcl.2008.04.026
Homo sapiens Huh-7 Activity 12.0 % 10.1016/j.bmcl.2005.09.015
Homo sapiens Huh-7 Activity 12.0 % 10.1016/j.bmcl.2013.12.121
Homo sapiens Huh-7 Activity 26.78 % 10.1016/j.ejmech.2017.10.001
Homo sapiens Huh-7 Activity 71.37 % 10.1016/j.ejmech.2017.10.001
Homo sapiens Huh-7 Activity 92.0 % 10.1016/j.bmc.2012.05.066
Homo sapiens Huh-7 Activity nan None 10.1016/j.bmc.2011.10.058
Homo sapiens Huh-7 CC50 8900.0 nM 10.1039/d3md00055a
Homo sapiens Huh-7 CC50 32000.0 nM 10.1016/j.bmc.2011.10.058
Homo sapiens Huh-7 CC50 56310.0 nM 10.1016/j.ejmech.2017.10.001
Homo sapiens Huh-7 CC50 100000.0 nM 10.1021/acs.jmedchem.0c01039
Homo sapiens Huh-7 CC50 100000.0 nM 10.1021/acsmedchemlett.9b00681
Homo sapiens Huh-7 CC50 200000.0 nM 10.1016/j.ejmech.2021.113683
Homo sapiens Huh-7 CC50 512800.0 nM 10.1016/j.ejmech.2022.114275
Homo sapiens Huh-7 CC50 nan None 10.1016/j.bmcl.2012.08.042
Homo sapiens Huh-7 CC50 nan None 10.1016/j.bmcl.2014.01.024
Homo sapiens Huh-7 CC50 nan None 10.1016/j.ejmech.2021.113683
Homo sapiens Huh-7 IC50 53700.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens Huh-7 IC50 200000.0 nM 10.1021/acs.jmedchem.8b01403
Homo sapiens Huh-7 Inhibition 60.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens Huh-7 Selectivity index 0.42 None 10.1016/j.bmcl.2005.09.015
Homo sapiens Huh-7.5 CC50 1654000.0 nM 10.1016/j.bmc.2022.116858
Homo sapiens IGROV-1 IC50 16.0 ug.mL-1 10.1016/j.ejmech.2019.112009
Homo sapiens IGROV-1 IC50 21.0 ug.mL-1 10.1016/j.ejmech.2019.112009
Homo sapiens IGROV-1 IC50 25.0 ug.mL-1 10.1016/j.ejmech.2019.112009
Homo sapiens Interleukin-8 Potency 66824.2 nM None
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens K562 ID50 50.0 uM 10.1021/jm00163a054
Homo sapiens Kappa opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens KB Activity nan None 10.1021/jm00206a005
Homo sapiens KB Activity nan None 10.1021/jm00210a008
Homo sapiens KB Activity nan None 10.1021/jm00228a022
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens Lymphoblastoid cell Potency 25118.9 nM None
Homo sapiens Lymphoblastoid cell Potency 31622.8 nM None
Homo sapiens Lymphoblastoid cell Potency 39810.7 nM None
Homo sapiens Lymphoblastoid cell Potency 79432.8 nM None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens MDA-MB-231 IC50 100000.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens MDA-MB-231 Inhibition 40.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens MDA-MB-435 IC50 38300.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens MDA-MB-435 Inhibition 50.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens Melanocortin receptor 3 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens MOLT-4 IC50 5700.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MT4 CC50 31000.0 nM 10.1016/j.bmc.2009.05.020
Homo sapiens MT4 CC50 31000.0 nM 10.1016/j.bmc.2010.02.037
Homo sapiens MT4 CC50 31000.0 nM 10.1016/j.bmc.2014.06.043
Homo sapiens MT4 CC50 31000.0 nM 10.1016/j.bmc.2015.09.035
Homo sapiens MT4 CC50 nan None 10.1016/j.bmc.2015.12.008
Homo sapiens MT4 IC50 5.0 ug.mL-1 10.1021/jm00075a030
Homo sapiens MT4 IC50 6.5 ug.mL-1 10.1021/jm00075a030
Homo sapiens MT4 IC50 23000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Norepinephrine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 10322.5 nM None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 11582.1 nM None
Homo sapiens Nuclear receptor ROR-gamma Potency 18833.6 nM None
Homo sapiens Peripheral myelin protein 22 Potency 23934.1 nM None
Homo sapiens Peroxisome proliferator-activated receptor alpha Inhibition nan % 10.1016/j.bmcl.2013.07.005
Homo sapiens Peroxisome proliferator-activated receptor delta IC50 nan None 10.1016/j.bmcl.2013.07.005
Homo sapiens Peroxisome proliferator-activated receptor delta Inhibition nan % 10.1016/j.bmcl.2013.07.005
Homo sapiens Peroxisome proliferator-activated receptor gamma Potency 50118.7 nM None
Homo sapiens P-glycoprotein 1 Inhibition nan % 10.1021/acsmedchemlett.2c00196
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Prelamin-A/C Potency 4.0 nM None
Homo sapiens Progesterone receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Purine nucleoside phosphorylase Ki nan nM 10.1021/jm00397a010
Homo sapiens Raji IC50 56000.0 nM 10.1016/0960-894X(96)00216-8
Homo sapiens Rap guanine nucleotide exchange factor 3 Potency 89125.1 nM None
Homo sapiens RD CC50 485.9 ug.mL-1 10.1016/j.ejmech.2017.08.057
Homo sapiens RD CC50 1485000.0 nM 10.1021/acs.jnatprod.8b00735
Homo sapiens RD CC50 nan None 10.1016/j.bmcl.2012.01.102
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens SK-OV-3 IC50 9.0 ug.mL-1 10.1016/j.ejmech.2019.112009
Homo sapiens SK-OV-3 IC50 10.0 ug.mL-1 10.1016/j.ejmech.2019.112009
Homo sapiens SNB-19 CC50 485200.0 nM 10.1016/j.ejmech.2022.114275
Homo sapiens SNB-75 IC50 18530.0 nM 10.1016/j.ejmech.2019.112009
Homo sapiens SNB-75 Inhibition 70.0 % 10.1016/j.ejmech.2019.112009
Homo sapiens Sodium channel protein type V alpha subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 112.33 % 10.1124/mol.112.084152
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition 87.39 % 10.1124/mol.112.084152
Homo sapiens Survival motor neuron protein Potency 19952.6 nM None
Homo sapiens Survival motor neuron protein Potency 22387.2 nM None
Homo sapiens THP-1 Ratio IC50 0.5 None None
Homo sapiens Thrombopoietin Potency 12589.3 nM None
Homo sapiens Thromboxane A2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Thyroid stimulating hormone receptor Potency 15848.9 nM None
Homo sapiens Type-1 angiotensin II receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 nan None None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 1032.3 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 1158.2 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 1458.1 nM None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Voltage-gated L-type calcium channel IC50 622500.0 nM 10.1038/srep02100
Homo sapiens Voltage-gated L-type calcium channel alpha-1C subunit AC50 50000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens WI-38 MCC 70.0 ug.mL-1 10.1021/jm00152a007
Homo sapiens WI-38 MCC 150.0 ug.mL-1 10.1021/jm00152a007
Homo sapiens WI-38 MCC 400.0 ug.mL-1 10.1021/jm00152a007
Homo sapiens WI-38 MCC 400.0 ug.mL-1 10.1021/jm00389a005
Homo sapiens WI-38 MIC 150.0 ug.mL-1 10.1021/jm00389a005
Homo sapiens WI-38 MIC 400.0 ug.mL-1 10.1021/jm00389a005
Homo sapiens WIL2-NS IC50 100000.0 nM 10.1016/0960-894X(96)00216-8
Human adenovirus 2 Human adenovirus 2 IC50 100000.0 nM 10.1016/j.bmc.2008.11.075
Human adenovirus 2 Human adenovirus 2 Rating 0.3 None 10.1021/jm00124a005
Human adenovirus 5 Human adenovirus 5 Activity nan None 10.1016/j.ejmech.2021.113738
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Activity 100.0 PFU/ml 10.1016/j.bmcl.2021.128405
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Activity nan None 10.1016/j.ejmech.2011.11.021
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Activity nan None 10.1016/j.ejmech.2021.113738
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Activity nan None 10.1021/jm00206a005
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Activity nan None 10.1021/jm00210a008
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Activity nan None 10.1021/jm00228a022
Human alphaherpesvirus 1 Human alphaherpesvirus 1 CPE50 75.0 ug ml-1 10.1021/jm00383a027
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC 10.0 ug ml-1 10.1021/acs.jnatprod.2c00464
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 1.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 2.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 20.0 ug.mL-1 10.1021/jm0701472
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 48.0 ug.mL-1 10.1021/jm025569k
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 70.0 ug.mL-1 10.1021/jm0701472
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 240.0 ug.mL-1 10.1021/jm025569k
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 400.0 ug.mL-1 10.1021/jm100093p
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 10000.0 nM 10.1016/j.ejmech.2009.12.002
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 100000.0 nM 10.1016/j.bmc.2009.05.020
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 100000.0 nM 10.1016/j.bmc.2010.02.037
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 125000.0 nM 10.1016/j.ejmech.2009.12.002
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250000.0 nM 10.1007/s00044-009-9248-y
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250000.0 nM 10.1016/j.bmc.2012.03.004
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250000.0 nM 10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250000.0 nM 10.1021/jm801470b
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 250000.0 nM 10.1039/c1md00094b
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 300000.0 nM 10.1021/jm060030y
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 500000.0 nM 10.1021/jm060030y
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 nan None 10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1 Human alphaherpesvirus 1 FC 10.0 None 10.1021/acs.jnatprod.2c00464
Human alphaherpesvirus 1 Human alphaherpesvirus 1 FC nan None 10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 38.49 ug.mL-1 10.1016/j.bmc.2018.12.014
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 125.0 ug.mL-1 10.1016/j.bmcl.2017.11.029
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 10000.0 nM 10.1016/j.bmcl.2016.05.072
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 512000.0 nM 10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 1024000.0 nM 10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 nan None 10.1021/np050498o
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC95 2048000.0 nM 10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC95 4095000.0 nM 10.1016/j.bmcl.2017.03.100
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 9.6 ug.mL-1 10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 23.0 ug.mL-1 10.1021/jm00045a025
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 53.0 ug.mL-1 10.1021/jm00045a025
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 115.0 ug.mL-1 10.1021/jm00045a025
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 300.0 ug.mL-1 10.1021/jm00035a010
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00102a010
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00130a024
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00157a016
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00167a011
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00369a010
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00373a020
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 400.0 ug.mL-1 10.1021/jm00378a037
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 250000.0 nM 10.1021/jm070324z
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC 500000.0 nM 10.1016/j.bmc.2006.10.046
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC50 20.0 ug.mL-1 10.1021/jm00220a027
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC50 200.0 ug.mL-1 10.1021/jm950891z
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC50 240.0 ug.mL-1 10.1021/jm050772b
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC50 400.0 ug.mL-1 10.1021/jm00386a007
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MIC50 400.0 ug.mL-1 10.1021/jm050772b
Human alphaherpesvirus 1 Human alphaherpesvirus 1 MNTD nan None 10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Tox50 400.0 ug ml-1 10.1021/jm00383a027
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Virus rating 0.6 None 10.1021/jm00377a002
Human alphaherpesvirus 1 Human alphaherpesvirus 1 VR 1.2 None 10.1021/jm00142a010
Human alphaherpesvirus 2 Human alphaherpesvirus 2 Activity nan None 10.1016/j.ejmech.2011.11.021
Human alphaherpesvirus 2 Human alphaherpesvirus 2 Activity nan None 10.1021/jm00126a027
Human alphaherpesvirus 2 Human alphaherpesvirus 2 Activity nan None 10.1021/jm00210a008
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 2.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 150.0 ug.mL-1 10.1021/jm0701472
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 400.0 ug.mL-1 10.1021/jm100093p
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 50000.0 nM 10.1016/j.ejmech.2009.12.002
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250000.0 nM 10.1007/s00044-009-9248-y
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250000.0 nM 10.1016/j.bmc.2012.03.004
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250000.0 nM 10.1016/j.ejmech.2010.12.017
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250000.0 nM 10.1021/jm801470b
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 250000.0 nM 10.1039/c1md00094b
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 500000.0 nM 10.1021/jm060030y
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 nan None 10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2 Human alphaherpesvirus 2 ED50 0.00019 M 10.1021/jm00148a015
Human alphaherpesvirus 2 Human alphaherpesvirus 2 ED50 0.00019 M 10.1021/jm00152a016
Human alphaherpesvirus 2 Human alphaherpesvirus 2 ED50 1.9 M 10.1021/jm00147a013
Human alphaherpesvirus 2 Human alphaherpesvirus 2 FC nan None 10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 300.0 ug.mL-1 10.1021/jm00130a024
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 400.0 ug.mL-1 10.1021/jm00102a010
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 400.0 ug.mL-1 10.1021/jm00157a016
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 400.0 ug.mL-1 10.1021/jm00167a011
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 400.0 ug.mL-1 10.1021/jm00369a010
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 400.0 ug.mL-1 10.1021/jm00373a020
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 400.0 ug.mL-1 10.1021/jm00378a037
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 250000.0 nM 10.1021/jm070324z
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC 300000.0 nM 10.1016/j.bmc.2006.10.046
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC50 200.0 ug.mL-1 10.1021/jm950891z
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC50 400.0 ug.mL-1 10.1021/jm00386a007
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MIC50 400.0 ug.mL-1 10.1021/jm050772b
Human alphaherpesvirus 2 Human alphaherpesvirus 2 MNTD nan None 10.1016/j.ejmech.2015.11.009
Human alphaherpesvirus 2 Human alphaherpesvirus 2 Rating 1.4 None 10.1021/jm00124a005
Human alphaherpesvirus 3 Human alphaherpesvirus 3 Activity nan None 10.1016/j.ejmech.2011.11.021
Human alphaherpesvirus 3 Human alphaherpesvirus 3 MIC 43.0 ug.mL-1 10.1021/jm00045a025
Human betaherpesvirus 5 Human betaherpesvirus 5 Activity nan None 10.1016/j.ejmech.2011.11.021
Human betaherpesvirus 5 Human betaherpesvirus 5 EC50 10.0 ug.mL-1 10.1016/0960-894X(95)00270-4
Human betaherpesvirus 5 Human betaherpesvirus 5 EC50 100000.0 nM 10.1016/j.ejmech.2010.12.017
Human coronavirus 229E Human coronavirus 229E EC50 82600.0 nM 10.1039/d3md00055a
Human coronavirus 229E Human coronavirus 229E EC50 112000.0 nM 10.1016/j.ejmech.2016.10.002
Human coronavirus 229E Human coronavirus 229E EC50 112000.0 nM 10.1016/j.ejmech.2019.111739
Human coronavirus OC43 Human coronavirus OC43 EC50 170100.0 nM 10.1039/d3md00055a
Human immunodeficiency virus 1 Human immunodeficiency virus 1 Activity nan None 10.1016/j.ejmech.2011.11.021
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50000.0 nM 10.1016/j.bmc.2012.03.004
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 50000.0 nM 10.1039/c1md00094b
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmc.2011.04.016
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1016/j.bmc.2015.09.035
Human immunodeficiency virus 1 Human immunodeficiency virus 1 MIC 20.0 ug.mL-1 10.1021/jm00102a010
Human immunodeficiency virus 2 Human immunodeficiency virus 2 Activity nan None 10.1016/j.ejmech.2011.11.021
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 50000.0 nM 10.1016/j.bmc.2012.03.004
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 50000.0 nM 10.1039/c1md00094b
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1016/j.bmc.2011.04.016
Human orthopneumovirus Human orthopneumovirus EC50 1200.0 nM 10.1016/j.ejmech.2017.09.060
Human orthopneumovirus Human orthopneumovirus EC50 7000.0 nM 10.1016/j.bmc.2015.09.035
Human orthopneumovirus Human orthopneumovirus EC50 10000.0 nM 10.1016/j.ejmech.2015.06.024
Human respirovirus 1 Human respirovirus 1 TIME 240.0 hr 10.1021/jm00212a014
Human respirovirus 1 Human respirovirus 1 TIME 288.0 hr 10.1021/jm00212a014
Human respirovirus 3 Human respirovirus 3 Activity nan None 10.1016/j.ejmech.2011.11.021
Human respirovirus 3 Human respirovirus 3 Activity nan None 10.1021/jm00126a027
Human respirovirus 3 Human respirovirus 3 Activity nan None 10.1021/jm00206a005
Human respirovirus 3 Human respirovirus 3 Activity nan None 10.1021/jm00210a008
Human respirovirus 3 Human respirovirus 3 Activity nan None 10.1021/jm00228a022
Human respirovirus 3 Human respirovirus 3 CC50 62.5 ug.mL-1 10.1021/np030470h
Human respirovirus 3 Human respirovirus 3 EC50 45.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Human respirovirus 3 Human respirovirus 3 EC50 45.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Human respirovirus 3 Human respirovirus 3 EC50 48.0 ug.mL-1 10.1021/jm061281+
Human respirovirus 3 Human respirovirus 3 EC50 48.0 ug.mL-1 10.1021/jm100093p
Human respirovirus 3 Human respirovirus 3 EC50 95.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Human respirovirus 3 Human respirovirus 3 EC50 120.0 ug.mL-1 10.1021/jm0707166
Human respirovirus 3 Human respirovirus 3 EC50 146.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Human respirovirus 3 Human respirovirus 3 EC50 29000.0 nM 10.1016/j.ejmech.2012.03.007
Human respirovirus 3 Human respirovirus 3 EC50 45000.0 nM 10.1007/s00044-009-9248-y
Human respirovirus 3 Human respirovirus 3 EC50 50000.0 nM 10.1007/s00044-012-0184-x
Human respirovirus 3 Human respirovirus 3 EC50 50000.0 nM 10.1021/jm801470b
Human respirovirus 3 Human respirovirus 3 EC50 73500.0 nM 10.1016/j.ejmech.2015.08.008
Human respirovirus 3 Human respirovirus 3 EC50 85000.0 nM 10.1016/j.bmc.2012.03.004
Human respirovirus 3 Human respirovirus 3 EC50 85000.0 nM 10.1016/j.ejmech.2013.06.036
Human respirovirus 3 Human respirovirus 3 EC50 85000.0 nM 10.1016/j.ejmech.2015.06.024
Human respirovirus 3 Human respirovirus 3 EC50 85000.0 nM 10.1039/c1md00094b
Human respirovirus 3 Human respirovirus 3 EC50 95000.0 nM 10.1016/j.bmc.2018.05.034
Human respirovirus 3 Human respirovirus 3 EC50 95000.0 nM 10.1016/j.ejmech.2009.12.002
Human respirovirus 3 Human respirovirus 3 EC50 112000.0 nM 10.1016/j.ejmech.2017.04.070
Human respirovirus 3 Human respirovirus 3 EC50 121000.0 nM 10.1016/j.bmc.2011.04.016
Human respirovirus 3 Human respirovirus 3 EC50 146000.0 nM 10.1016/j.ejmech.2013.05.046
Human respirovirus 3 Human respirovirus 3 EC50 150000.0 nM 10.1021/jm0614329
Human respirovirus 3 Human respirovirus 3 EC50 250000.0 nM 10.1016/j.bmc.2015.12.008
Human respirovirus 3 Human respirovirus 3 EC50 300000.0 nM 10.1021/jm060030y
Human respirovirus 3 Human respirovirus 3 ED50 0.00016 M 10.1021/jm00148a015
Human respirovirus 3 Human respirovirus 3 ED50 0.00016 M 10.1021/jm00152a016
Human respirovirus 3 Human respirovirus 3 ED50 1.6 M 10.1021/jm00147a013
Human respirovirus 3 Human respirovirus 3 IC50 2.6 ug.mL-1 10.1021/np010174+
Human respirovirus 3 Human respirovirus 3 IC50 2.6 ug.mL-1 10.1021/np030470h
Human respirovirus 3 Human respirovirus 3 IC50 10700.0 nM 10.1021/np800542t
Human respirovirus 3 Human respirovirus 3 ID50 17.5 ug ml-1 10.1021/jm00127a007
Human respirovirus 3 Human respirovirus 3 MIC 10.0 ug.mL-1 10.1021/jm00373a020
Human respirovirus 3 Human respirovirus 3 MIC 10.0 ug.mL-1 10.1021/jm00378a037
Human respirovirus 3 Human respirovirus 3 MIC 20.0 ug.mL-1 10.1021/jm00369a010
Human respirovirus 3 Human respirovirus 3 MIC 40.0 ug.mL-1 10.1021/jm00128a011
Human respirovirus 3 Human respirovirus 3 MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Human respirovirus 3 Human respirovirus 3 MIC 70.0 ug.mL-1 10.1021/jm00102a010
Human respirovirus 3 Human respirovirus 3 MIC 300.0 ug.mL-1 10.1007/s00044-012-0127-6
Human respirovirus 3 Human respirovirus 3 MIC 150000.0 nM 10.1021/jm070324z
Human respirovirus 3 Human respirovirus 3 MIC50 48.0 ug.mL-1 10.1021/jm050772b
Human respirovirus 3 Human respirovirus 3 MIC50 50.0 ug.mL-1 10.1021/jm00386a007
Human respirovirus 3 Human respirovirus 3 MIC50 150.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Human respirovirus 3 Human respirovirus 3 MIC50 150.0 ug.mL-1 10.1021/jm950891z
Human respirovirus 3 Human respirovirus 3 Rating 1.3 None 10.1021/jm00124a005
Human respirovirus 3 Human respirovirus 3 Virus rating 1.3 None 10.1021/jm00377a002
Human respirovirus 3 Human respirovirus 3 VR 2.5 None 10.1021/jm00127a007
Human rhinovirus 1A Human rhinovirus 1A Rating 0.7 None 10.1021/jm00124a005
Influenza A virus Influenza A virus Activity 4.0 HAU/ml 10.1021/jm00188a013
Influenza A virus Influenza A virus Activity 9.5 mM 10.1016/S0960-894X(01)80822-2
Influenza A virus Influenza A virus Activity 12.0 HAU/ml 10.1021/jm00188a013
Influenza A virus Influenza A virus Activity 12.0 mM 10.1016/S0960-894X(01)80822-2
Influenza A virus Influenza A virus Activity 14.0 day 10.1016/j.bmcl.2007.06.049
Influenza A virus Influenza A virus Activity 29.2 mM 10.1016/S0960-894X(01)80822-2
Influenza A virus Influenza A virus Activity nan None 10.1016/j.bmcl.2020.127518
Influenza A virus Influenza A virus Activity nan None 10.1016/j.ejmech.2011.11.021
Influenza A virus Influenza A virus Activity nan None 10.1021/jm00126a027
Influenza A virus Influenza A virus Activity nan None 10.1021/jm00224a016
Influenza A virus Influenza A virus Activity nan None 10.1021/jm00230a008
Influenza A virus Influenza A virus Activity nan None None
Influenza A virus Influenza A virus CC50 125.0 ug.mL-1 10.1021/np030470h
Influenza A virus Influenza A virus CC50 2000.0 ug.mL-1 10.1016/j.bmcl.2005.08.046
Influenza A virus Influenza A virus EC50 3.7 ug.mL-1 10.1021/np960613i
Influenza A virus Influenza A virus EC50 7.8 ug.mL-1 10.1016/j.ejmech.2010.07.058
Influenza A virus Influenza A virus EC50 8.4 ug.mL-1 10.1016/j.ejmech.2010.09.065
Influenza A virus Influenza A virus EC50 9.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Influenza A virus Influenza A virus EC50 9.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Influenza A virus Influenza A virus EC50 12.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Influenza A virus Influenza A virus EC50 12.9 ug.mL-1 10.1016/j.ejmech.2010.07.058
Influenza A virus Influenza A virus EC50 19.6 ug.mL-1 10.1016/0960-894X(95)00270-4
Influenza A virus Influenza A virus EC50 1050.0 nM 10.1016/j.ejmech.2015.09.037
Influenza A virus Influenza A virus EC50 1100.0 nM 10.1016/j.ejmech.2013.05.046
Influenza A virus Influenza A virus EC50 1430.0 nM 10.1016/j.ejmech.2015.09.037
Influenza A virus Influenza A virus EC50 1900.0 nM 10.1021/acsmedchemlett.3c00048
Influenza A virus Influenza A virus EC50 2000.0 nM 10.1016/j.ejmech.2013.12.055
Influenza A virus Influenza A virus EC50 2000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 2200.0 nM 10.1016/j.bmcl.2019.02.027
Influenza A virus Influenza A virus EC50 2300.0 nM 10.1016/j.bmc.2012.03.004
Influenza A virus Influenza A virus EC50 2500.0 nM 10.1016/j.ejmech.2013.05.046
Influenza A virus Influenza A virus EC50 3560.0 nM 10.1016/j.ejmech.2015.09.037
Influenza A virus Influenza A virus EC50 4000.0 nM 10.1039/d3md00055a
Influenza A virus Influenza A virus EC50 4200.0 nM 10.1016/j.ejmech.2013.12.055
Influenza A virus Influenza A virus EC50 4200.0 nM 10.1021/acs.jnatprod.2c00766
Influenza A virus Influenza A virus EC50 4920.0 nM 10.1128/aac.01739-09
Influenza A virus Influenza A virus EC50 5000.0 nM 10.1021/acs.jmedchem.8b00617
Influenza A virus Influenza A virus EC50 5060.0 nM 10.1021/acs.jmedchem.8b01065
Influenza A virus Influenza A virus EC50 5100.0 nM 10.1016/j.bmc.2012.03.004
Influenza A virus Influenza A virus EC50 5600.0 nM 10.1016/j.ejmech.2012.03.007
Influenza A virus Influenza A virus EC50 5800.0 nM 10.1021/acs.jmedchem.8b00617
Influenza A virus Influenza A virus EC50 6000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 6100.0 nM 10.1016/j.bmcl.2012.09.079
Influenza A virus Influenza A virus EC50 6700.0 nM 10.1016/j.ejmech.2012.03.007
Influenza A virus Influenza A virus EC50 6800.0 nM 10.1016/j.bmcl.2014.06.018
Influenza A virus Influenza A virus EC50 6800.0 nM 10.1016/j.ejmech.2012.10.030
Influenza A virus Influenza A virus EC50 6800.0 nM 10.1021/acsmedchemlett.5b00109
Influenza A virus Influenza A virus EC50 6900.0 nM 10.1016/j.ejmech.2015.06.024
Influenza A virus Influenza A virus EC50 7000.0 nM 10.1016/j.ejmech.2009.12.002
Influenza A virus Influenza A virus EC50 7000.0 nM 10.1016/j.ejmech.2012.03.007
Influenza A virus Influenza A virus EC50 7000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 7200.0 nM 10.1016/j.ejmech.2013.06.036
Influenza A virus Influenza A virus EC50 7200.0 nM 10.1016/j.ejmech.2015.06.024
Influenza A virus Influenza A virus EC50 7500.0 nM 10.1016/j.bmc.2016.04.010
Influenza A virus Influenza A virus EC50 7600.0 nM 10.1016/j.ejmech.2017.04.070
Influenza A virus Influenza A virus EC50 7600.0 nM 10.1021/ml300279b
Influenza A virus Influenza A virus EC50 8000.0 nM 10.1021/acs.jmedchem.5b00012
Influenza A virus Influenza A virus EC50 8000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 8200.0 nM 10.1021/ml300279b
Influenza A virus Influenza A virus EC50 8400.0 nM 10.1016/j.bmc.2012.09.064
Influenza A virus Influenza A virus EC50 8400.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC50 8400.0 nM 10.1016/j.ejmech.2018.08.058
Influenza A virus Influenza A virus EC50 8400.0 nM 10.1021/acsmedchemlett.5b00109
Influenza A virus Influenza A virus EC50 8500.0 nM 10.1016/j.bmc.2012.09.064
Influenza A virus Influenza A virus EC50 8500.0 nM 10.1016/j.ejmech.2018.08.058
Influenza A virus Influenza A virus EC50 8680.0 nM 10.1016/j.bmcl.2007.04.108
Influenza A virus Influenza A virus EC50 8700.0 nM 10.1016/j.bmc.2009.01.009
Influenza A virus Influenza A virus EC50 8700.0 nM 10.1016/j.bmcl.2010.03.080
Influenza A virus Influenza A virus EC50 8700.0 nM 10.1021/ml300279b
Influenza A virus Influenza A virus EC50 8800.0 nM 10.1021/ml300279b
Influenza A virus Influenza A virus EC50 8900.0 nM 10.1016/j.bmc.2012.09.064
Influenza A virus Influenza A virus EC50 8900.0 nM 10.1016/j.bmc.2015.12.008
Influenza A virus Influenza A virus EC50 8900.0 nM 10.1016/j.bmc.2018.05.034
Influenza A virus Influenza A virus EC50 8900.0 nM 10.1016/j.ejmech.2015.02.028
Influenza A virus Influenza A virus EC50 8900.0 nM 10.1016/j.ejmech.2019.111739
Influenza A virus Influenza A virus EC50 9000.0 nM 10.1016/j.bmc.2010.02.015
Influenza A virus Influenza A virus EC50 9000.0 nM 10.1016/j.bmcl.2010.03.080
Influenza A virus Influenza A virus EC50 9000.0 nM 10.1016/j.ejmech.2009.12.002
Influenza A virus Influenza A virus EC50 9000.0 nM 10.1016/j.ejmech.2015.02.028
Influenza A virus Influenza A virus EC50 9000.0 nM 10.1021/jm900950d
Influenza A virus Influenza A virus EC50 9000.0 nM 10.1039/c1md00094b
Influenza A virus Influenza A virus EC50 9100.0 nM 10.1016/j.ejmech.2018.08.058
Influenza A virus Influenza A virus EC50 9116.0 nM 10.1016/j.bmcl.2019.04.042
Influenza A virus Influenza A virus EC50 9600.0 nM 10.1016/j.ejmech.2013.06.036
Influenza A virus Influenza A virus EC50 9700.0 nM 10.1021/jm900950d
Influenza A virus Influenza A virus EC50 9800.0 nM 10.1016/j.bmc.2011.04.016
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1016/j.ejmech.2013.12.055
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1016/j.ejmech.2017.04.070
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1016/j.ejmech.2017.06.015
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1016/j.ejmech.2018.08.058
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1016/j.ejmech.2020.112944
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1016/j.ejmech.2021.113494
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1021/acs.jmedchem.8b00617
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1021/acsmedchemlett.3c00048
Influenza A virus Influenza A virus EC50 10000.0 nM 10.1021/ml300279b
Influenza A virus Influenza A virus EC50 10500.0 nM 10.1039/d3md00055a
Influenza A virus Influenza A virus EC50 11000.0 nM 10.1016/j.bmcl.2010.03.080
Influenza A virus Influenza A virus EC50 11000.0 nM 10.1016/j.bmcl.2014.06.018
Influenza A virus Influenza A virus EC50 11000.0 nM 10.1016/j.ejmech.2018.05.059
Influenza A virus Influenza A virus EC50 11000.0 nM 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 11000.0 nM 10.1021/acs.jmedchem.7b00908
Influenza A virus Influenza A virus EC50 11000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 11200.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC50 11270.0 nM 10.1021/acs.jmedchem.8b01065
Influenza A virus Influenza A virus EC50 11330.0 nM 10.1021/acs.jmedchem.8b01065
Influenza A virus Influenza A virus EC50 11500.0 nM 10.1007/s00044-012-0184-x
Influenza A virus Influenza A virus EC50 12000.0 nM 10.1016/j.bmcl.2014.06.018
Influenza A virus Influenza A virus EC50 12000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 12500.0 nM 10.1016/j.bmc.2011.04.016
Influenza A virus Influenza A virus EC50 12800.0 nM 10.1016/j.ejmech.2018.08.032
Influenza A virus Influenza A virus EC50 12800.0 nM 10.1021/acs.jmedchem.5b01935
Influenza A virus Influenza A virus EC50 13000.0 nM 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 13000.0 nM 10.1021/acs.jmedchem.8b00617
Influenza A virus Influenza A virus EC50 13900.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC50 14300.0 nM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC50 15000.0 nM 10.1021/acs.jmedchem.7b00908
Influenza A virus Influenza A virus EC50 15600.0 nM 10.1021/jm500300r
Influenza A virus Influenza A virus EC50 15810.0 nM 10.1021/acs.jmedchem.8b01065
Influenza A virus Influenza A virus EC50 16000.0 nM 10.1016/j.ejmech.2019.111861
Influenza A virus Influenza A virus EC50 16000.0 nM 10.1021/acs.jmedchem.7b00908
Influenza A virus Influenza A virus EC50 16400.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC50 17000.0 nM 10.1021/jm401560v
Influenza A virus Influenza A virus EC50 18200.0 nM 10.1016/j.ejmech.2019.111739
Influenza A virus Influenza A virus EC50 18430.0 nM 10.1016/j.ejmech.2013.05.044
Influenza A virus Influenza A virus EC50 19400.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC50 19670.0 nM 10.1128/aac.01739-09
Influenza A virus Influenza A virus EC50 20000.0 nM 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 20200.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC50 20920.0 nM 10.1128/aac.01739-09
Influenza A virus Influenza A virus EC50 21000.0 nM 10.1016/j.bmcl.2014.06.018
Influenza A virus Influenza A virus EC50 21000.0 nM 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 21910.0 nM 10.1016/j.bmcl.2023.129219
Influenza A virus Influenza A virus EC50 22000.0 nM 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 23750.0 nM 10.1016/j.ejmech.2013.05.044
Influenza A virus Influenza A virus EC50 25080.0 nM 10.1016/j.ejmech.2019.111861
Influenza A virus Influenza A virus EC50 31000.0 nM 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 32200.0 nM 10.1016/j.bmcl.2019.02.027
Influenza A virus Influenza A virus EC50 35600.0 nM 10.1128/aac.01739-09
Influenza A virus Influenza A virus EC50 35700.0 nM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC50 37700.0 nM 10.1016/j.bmcl.2023.129174
Influenza A virus Influenza A virus EC50 38100.0 nM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC50 38700.0 nM 10.1016/j.bmcl.2023.129174
Influenza A virus Influenza A virus EC50 43000.0 nM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC50 45000.0 nM 10.1021/acs.jmedchem.7b00908
Influenza A virus Influenza A virus EC50 46700.0 nM 10.1128/aac.01739-09
Influenza A virus Influenza A virus EC50 900000.0 nM 10.1021/jm801470b
Influenza A virus Influenza A virus EC50 8400000.0 nM 10.1021/jm801470b
Influenza A virus Influenza A virus EC50 nan None 10.1016/j.bmcl.2013.07.023
Influenza A virus Influenza A virus EC90 3.5 uM 10.1016/j.bmcl.2019.02.027
Influenza A virus Influenza A virus EC90 11.6 uM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC90 13.0 uM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC90 18.4 uM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC90 20.1 uM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC90 21.7 uM 10.1016/j.bmcl.2010.02.074
Influenza A virus Influenza A virus EC90 32.0 uM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC90 33.2 uM 10.1128/aac.01051-06
Influenza A virus Influenza A virus EC90 68.6 uM 10.1016/j.bmcl.2019.02.027
Influenza A virus Influenza A virus EC99 11.0 uM 10.1021/acsmedchemlett.5b00109
Influenza A virus Influenza A virus ED50 24.6 uM 10.1016/j.bmcl.2012.09.084
Influenza A virus Influenza A virus IC50 1.92 ug.mL-1 10.1016/j.ejmech.2014.02.029
Influenza A virus Influenza A virus IC50 2.0 nM 10.1021/acs.jnatprod.7b00014
Influenza A virus Influenza A virus IC50 2.1 ug.mL-1 10.1016/j.bmcl.2016.06.011
Influenza A virus Influenza A virus IC50 3.73 ug.mL-1 10.1016/j.bmcl.2005.08.046
Influenza A virus Influenza A virus IC50 5.54 ug.mL-1 10.1016/j.ejmech.2020.112541
Influenza A virus Influenza A virus IC50 5.59 ug.mL-1 10.1016/j.ejmech.2014.02.029
Influenza A virus Influenza A virus IC50 6.5 ug.mL-1 10.1016/j.ejmech.2014.02.029
Influenza A virus Influenza A virus IC50 12.5 ug.mL-1 10.1016/j.bmcl.2017.11.029
Influenza A virus Influenza A virus IC50 24.6 ug.mL-1 10.1016/j.bmcl.2013.01.051
Influenza A virus Influenza A virus IC50 62.5 ug.mL-1 10.1021/np030470h
Influenza A virus Influenza A virus IC50 410.0 nM 10.1021/np300897v
Influenza A virus Influenza A virus IC50 1050.0 nM 10.1016/j.ejmech.2015.02.006
Influenza A virus Influenza A virus IC50 1300.0 nM 10.1021/acs.jnatprod.6b00585
Influenza A virus Influenza A virus IC50 1900.0 nM 10.1016/j.bmcl.2012.01.056
Influenza A virus Influenza A virus IC50 1960.0 nM 10.1016/j.ejmech.2020.112147
Influenza A virus Influenza A virus IC50 2060.0 ug.mL-1 10.1016/j.bmcl.2007.11.117
Influenza A virus Influenza A virus IC50 2840.0 nM 10.1016/j.ejmech.2020.112334
Influenza A virus Influenza A virus IC50 3900.0 nM 10.1016/j.bmcl.2012.01.056
Influenza A virus Influenza A virus IC50 4010.0 nM 10.1016/j.ejmech.2020.112147
Influenza A virus Influenza A virus IC50 4280.0 nM 10.1016/j.ejmech.2021.113591
Influenza A virus Influenza A virus IC50 5040.0 nM 10.1016/j.bmcl.2007.06.049
Influenza A virus Influenza A virus IC50 5850.0 nM 10.1016/j.bmcl.2007.06.049
Influenza A virus Influenza A virus IC50 5860.0 nM 10.1021/acs.jnatprod.5b00325
Influenza A virus Influenza A virus IC50 6190.0 nM 10.1016/j.ejmech.2020.112577
Influenza A virus Influenza A virus IC50 6680.0 nM 10.1016/j.ejmech.2020.112147
Influenza A virus Influenza A virus IC50 7010.0 nM 10.1016/j.bmcl.2007.06.049
Influenza A virus Influenza A virus IC50 7700.0 nM 10.1016/j.bmc.2008.11.075
Influenza A virus Influenza A virus IC50 8500.0 nM 10.1016/j.bmcl.2019.08.009
Influenza A virus Influenza A virus IC50 8800.0 nM 10.1016/j.ejmech.2012.07.008
Influenza A virus Influenza A virus IC50 9500.0 nM 10.1016/j.ejmech.2021.113683
Influenza A virus Influenza A virus IC50 10000.0 nM 10.1016/j.ejmech.2020.112147
Influenza A virus Influenza A virus IC50 14000.0 nM 10.1016/j.bmc.2013.10.026
Influenza A virus Influenza A virus IC50 15360.0 nM 10.1016/j.bmcl.2020.127143
Influenza A virus Influenza A virus IC50 15360.0 nM 10.1016/j.ejmech.2020.112706
Influenza A virus Influenza A virus IC50 15360.0 nM 10.1016/j.ejmech.2021.113208
Influenza A virus Influenza A virus IC50 20200.0 nM 10.1021/np300897v
Influenza A virus Influenza A virus IC50 22600.0 nM 10.1016/j.bmcl.2018.03.080
Influenza A virus Influenza A virus IC50 24600.0 nM 10.1039/C6MD00657D
Influenza A virus Influenza A virus IC50 25620.0 nM 10.1016/j.bmc.2008.06.049
Influenza A virus Influenza A virus IC50 27760.0 nM 10.1016/j.bmcl.2022.128681
Influenza A virus Influenza A virus IC50 30000.0 nM 10.1039/C8MD00442K
Influenza A virus Influenza A virus IC50 35000.0 nM 10.1016/j.bmcl.2020.127677
Influenza A virus Influenza A virus IC50 35300.0 nM 10.1016/j.ejmech.2012.07.008
Influenza A virus Influenza A virus IC50 37400.0 nM 10.1016/j.ejmech.2021.113683
Influenza A virus Influenza A virus IC50 38800.0 nM 10.1016/j.ejmech.2020.112790
Influenza A virus Influenza A virus IC50 42600.0 nM 10.1021/np800542t
Influenza A virus Influenza A virus IC50 44000.0 nM 10.1016/j.bmcl.2018.04.057
Influenza A virus Influenza A virus IC50 47220.0 nM 10.1016/j.bmcl.2020.127518
Influenza A virus Influenza A virus IC50 66700.0 nM 10.1016/j.bmcl.2018.07.029
Influenza A virus Influenza A virus IC50 84000.0 nM 10.1021/np400977e
Influenza A virus Influenza A virus IC50 87000.0 nM 10.1021/np400200k
Influenza A virus Influenza A virus IC50 98300.0 nM 10.1021/acs.jmedchem.0c00312
Influenza A virus Influenza A virus IC50 100800.0 nM 10.1021/np2004769
Influenza A virus Influenza A virus IC50 101000.0 nM 10.1021/np500458a
Influenza A virus Influenza A virus IC50 103000.0 nM 10.1021/acs.jnatprod.6b01061
Influenza A virus Influenza A virus IC50 114800.0 nM 10.1016/j.bmcl.2012.03.044
Influenza A virus Influenza A virus IC50 115000.0 nM 10.1021/acs.jnatprod.5b00103
Influenza A virus Influenza A virus IC50 131000.0 nM 10.1021/np400833x
Influenza A virus Influenza A virus IC50 133000.0 nM 10.1016/j.ejmech.2020.112790
Influenza A virus Influenza A virus IC50 150380.0 nM 10.1016/j.ejmech.2015.02.006
Influenza A virus Influenza A virus IC50 176000.0 nM 10.1016/j.bmcl.2007.06.049
Influenza A virus Influenza A virus IC50 185900.0 nM 10.1021/acs.jnatprod.5b00151
Influenza A virus Influenza A virus IC50 nan None 10.1021/np050498o
Influenza A virus Influenza A virus Inhibition 45.3 % 10.1016/j.ejmech.2020.112790
Influenza A virus Influenza A virus Inhibition nan % 10.1016/j.bmcl.2018.03.080
Influenza A virus Influenza A virus IZ 28.0 mm 10.1021/jm00199a015
Influenza A virus Influenza A virus IZ 30.0 mm 10.1021/jm00188a013
Influenza A virus Influenza A virus MIC 15.0 ug.mL-1 10.1021/jm00095a019
Influenza A virus Influenza A virus PDD50 1.0 ug ml-1 10.1021/jm00199a015
Influenza A virus Influenza A virus PDD50 2.0 ug ml-1 10.1021/jm00188a013
Influenza A virus Influenza A virus RFU 0.67 None 10.1016/j.ejmech.2019.111861
Influenza A virus Influenza A virus Survival 100.0 % 10.1016/j.bmcl.2007.06.049
Influenza A virus Influenza A virus T 39.5 degrees C 10.1021/jm00188a013
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1)) EC50 8700.0 nM 10.1016/j.bmc.2016.04.010
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1)) EC50 23300.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1)) EC50 25100.0 nM 10.1016/j.bmcl.2010.02.074
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1)) EC90 27.0 uM 10.1016/j.bmcl.2010.02.074
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50 25000.0 nM 10.1016/j.bmcl.2019.126745
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50 113100.0 nM 10.1021/np400304q
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) PA/PB1 EC50 23800.0 nM 10.1016/j.ejmech.2018.08.032
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) PA/PB1 IC50 nan None 10.1021/acs.jmedchem.5b00012
Influenza A virus (A/Puerto Rico/8/1934(H1N1)) PA/PB1 IC50 nan None 10.1021/acs.jmedchem.5b01935
Influenza A virus H3N2 Influenza A virus H3N2 EC50 1400.0 nM 10.1016/j.ejmech.2019.111739
Influenza A virus H3N2 Influenza A virus H3N2 EC50 2300.0 nM 10.1016/j.ejmech.2019.111739
Influenza A virus H3N2 Influenza A virus H3N2 EC50 4600.0 nM 10.1016/j.bmc.2019.115130
Influenza A virus H3N2 Influenza A virus H3N2 EC50 6800.0 nM 10.1007/s00044-012-0184-x
Influenza A virus H3N2 Influenza A virus H3N2 EC50 8100.0 nM 10.1021/jm801470b
Influenza A virus H3N2 Influenza A virus H3N2 EC50 8400.0 nM 10.1016/j.bmc.2019.115130
Influenza A virus H3N2 Influenza A virus H3N2 EC50 8600.0 nM 10.1016/j.bmc.2018.05.034
Influenza A virus H3N2 Influenza A virus H3N2 EC50 8900.0 nM 10.1016/j.bmc.2018.05.034
Influenza A virus H3N2 Influenza A virus H3N2 EC50 9000.0 nM 10.1021/jm801470b
Influenza A virus H3N2 Influenza A virus H3N2 EC50 9000.0 nM 10.1039/c1md00094b
Influenza A virus H3N2 Influenza A virus H3N2 EC50 28800.0 nM 10.1016/j.bmcl.2019.02.027
Influenza A virus H3N2 Influenza A virus H3N2 EC90 34.9 uM 10.1016/j.bmcl.2019.02.027
Influenza A virus H3N2 Influenza A virus H3N2 IC50 1.1 ug.mL-1 10.1016/j.bmcl.2016.06.011
Influenza A virus H3N2 Influenza A virus H3N2 IC50 87.7 ug.mL-1 10.1016/j.bmcl.2015.12.100
Influenza A virus H3N2 Influenza A virus H3N2 IC50 10600.0 nM 10.1016/j.bmcl.2019.08.009
Influenza A virus H3N2 Influenza A virus H3N2 IC50 20000.0 nM 10.1016/j.bmc.2008.11.075
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) RNA-directed RNA polymerase EC50 16000.0 nM 10.1016/j.ejmech.2021.113494
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) RNA-directed RNA polymerase EC50 24000.0 nM 10.1016/j.ejmech.2020.112944
Influenza B virus Influenza B virus Activity nan None 10.1016/j.bmc.2009.01.009
Influenza B virus Influenza B virus Activity nan None 10.1016/j.ejmech.2011.11.021
Influenza B virus Influenza B virus EC50 4.3 ug.mL-1 10.1016/j.ejmech.2010.09.065
Influenza B virus Influenza B virus EC50 6.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Influenza B virus Influenza B virus EC50 6.7 ug.mL-1 10.1016/0960-894X(95)00270-4
Influenza B virus Influenza B virus EC50 7.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Influenza B virus Influenza B virus EC50 9.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Influenza B virus Influenza B virus EC50 36.9 ug.mL-1 10.1016/0960-894X(95)00270-4
Influenza B virus Influenza B virus EC50 94.0 nM 10.1016/j.bmc.2012.09.064
Influenza B virus Influenza B virus EC50 140.0 nM 10.1016/j.bmc.2012.09.064
Influenza B virus Influenza B virus EC50 1500.0 nM 10.1021/acs.jmedchem.8b00617
Influenza B virus Influenza B virus EC50 1900.0 nM 10.1021/acsmedchemlett.3c00048
Influenza B virus Influenza B virus EC50 2200.0 nM 10.1016/j.ejmech.2018.08.058
Influenza B virus Influenza B virus EC50 2200.0 nM 10.1021/acs.jmedchem.8b00617
Influenza B virus Influenza B virus EC50 2300.0 nM 10.1016/j.bmc.2015.12.008
Influenza B virus Influenza B virus EC50 2300.0 nM 10.1016/j.ejmech.2018.08.058
Influenza B virus Influenza B virus EC50 2400.0 nM 10.1016/j.ejmech.2013.12.055
Influenza B virus Influenza B virus EC50 2800.0 nM 10.1016/j.ejmech.2013.05.046
Influenza B virus Influenza B virus EC50 2800.0 nM 10.1039/d3md00055a
Influenza B virus Influenza B virus EC50 3200.0 nM 10.1016/j.ejmech.2018.05.059
Influenza B virus Influenza B virus EC50 3400.0 nM 10.1016/j.ejmech.2015.02.028
Influenza B virus Influenza B virus EC50 3600.0 nM 10.1021/jm900950d
Influenza B virus Influenza B virus EC50 4000.0 nM 10.1016/j.bmcl.2010.03.080
Influenza B virus Influenza B virus EC50 4000.0 nM 10.1016/j.ejmech.2015.06.024
Influenza B virus Influenza B virus EC50 4000.0 nM 10.1021/jm801470b
Influenza B virus Influenza B virus EC50 4280.0 nM 10.1016/j.ejmech.2015.09.037
Influenza B virus Influenza B virus EC50 4500.0 nM 10.1016/j.bmc.2012.03.004
Influenza B virus Influenza B virus EC50 4500.0 nM 10.1021/acs.jmedchem.8b00617
Influenza B virus Influenza B virus EC50 4600.0 nM 10.1016/j.bmcl.2012.09.079
Influenza B virus Influenza B virus EC50 4600.0 nM 10.1016/j.ejmech.2019.111739
Influenza B virus Influenza B virus EC50 4700.0 nM 10.1016/j.bmcl.2010.03.080
Influenza B virus Influenza B virus EC50 4800.0 nM 10.1016/j.ejmech.2012.03.007
Influenza B virus Influenza B virus EC50 4800.0 nM 10.1021/jm801470b
Influenza B virus Influenza B virus EC50 4900.0 nM 10.1016/j.ejmech.2017.04.070
Influenza B virus Influenza B virus EC50 5600.0 nM 10.1016/j.ejmech.2019.111739
Influenza B virus Influenza B virus EC50 5730.0 nM 10.1016/j.ejmech.2013.05.044
Influenza B virus Influenza B virus EC50 5900.0 nM 10.1021/acs.jmedchem.8b00617
Influenza B virus Influenza B virus EC50 6000.0 nM 10.1021/jm401560v
Influenza B virus Influenza B virus EC50 7000.0 nM 10.1016/j.ejmech.2012.03.007
Influenza B virus Influenza B virus EC50 7000.0 nM 10.1016/j.ejmech.2015.02.028
Influenza B virus Influenza B virus EC50 7300.0 nM 10.1016/j.bmc.2011.04.016
Influenza B virus Influenza B virus EC50 8000.0 nM 10.1021/ml300279b
Influenza B virus Influenza B virus EC50 8100.0 nM 10.1021/ml300279b
Influenza B virus Influenza B virus EC50 8200.0 nM 10.1016/j.bmcl.2014.06.018
Influenza B virus Influenza B virus EC50 8300.0 nM 10.1016/j.ejmech.2013.06.036
Influenza B virus Influenza B virus EC50 8400.0 nM 10.1007/s00044-012-0184-x
Influenza B virus Influenza B virus EC50 8900.0 nM 10.1016/j.bmc.2018.05.034
Influenza B virus Influenza B virus EC50 8900.0 nM 10.1016/j.bmcl.2014.06.018
Influenza B virus Influenza B virus EC50 8900.0 nM 10.1016/j.ejmech.2012.10.030
Influenza B virus Influenza B virus EC50 9000.0 nM 10.1016/j.bmc.2010.02.015
Influenza B virus Influenza B virus EC50 9000.0 nM 10.1016/j.ejmech.2009.12.002
Influenza B virus Influenza B virus EC50 9000.0 nM 10.1021/jm900950d
Influenza B virus Influenza B virus EC50 9000.0 nM 10.1039/c1md00094b
Influenza B virus Influenza B virus EC50 9800.0 nM 10.1016/j.bmc.2018.05.034
Influenza B virus Influenza B virus EC50 10200.0 nM 10.1016/j.bmcl.2010.02.074
Influenza B virus Influenza B virus EC50 13930.0 nM 10.1128/aac.01739-09
Influenza B virus Influenza B virus EC50 19500.0 nM 10.1016/j.bmcl.2010.02.074
Influenza B virus Influenza B virus EC50 25000.0 nM 10.1128/aac.01739-09
Influenza B virus Influenza B virus EC50 33300.0 nM 10.1016/j.bmcl.2023.129174
Influenza B virus Influenza B virus EC90 22.2 uM 10.1016/j.bmcl.2010.02.074
Influenza B virus Influenza B virus IC50 0.8 ug.mL-1 10.1016/j.bmcl.2016.06.011
Influenza B virus Influenza B virus IC50 3.27 ug.mL-1 10.1016/j.ejmech.2014.02.029
Influenza B virus Influenza B virus IC50 7.84 ug.mL-1 10.1016/j.ejmech.2014.02.029
Influenza B virus Influenza B virus IC50 4270.0 ug.mL-1 10.1016/j.bmcl.2007.11.117
Influenza B virus Influenza B virus IC50 8000.0 nM 10.1016/j.bmcl.2019.08.009
Influenza B virus Influenza B virus IC50 9000.0 nM 10.1016/j.bmc.2015.07.039
Influenza B virus Influenza B virus IC50 14700.0 nM 10.1016/j.bmcl.2012.01.056
Influenza B virus Influenza B virus IC50 15200.0 nM 10.1016/j.bmcl.2007.06.049
Influenza B virus Influenza B virus IC50 19000.0 nM 10.1016/j.bmc.2008.11.075
Influenza B virus Influenza B virus IC50 45500.0 nM 10.1016/j.ejmech.2012.07.008
Influenza B virus Influenza B virus IC50 96200.0 nM 10.1016/j.bmcl.2007.06.049
Influenza B virus Influenza B virus IC50 164000.0 nM 10.1016/j.bmcl.2007.06.049
Influenza B virus Influenza B virus MIC 15.0 ug.mL-1 10.1021/jm00095a019
Influenza B virus Influenza B virus MIC50 2.4 ug.mL-1 10.1021/jm950891z
Japanese encephalitis virus Japanese encephalitis virus ID50 3.0 ug ml-1 10.1021/jm00117a004
Japanese encephalitis virus Japanese encephalitis virus Virus rating 2.4 None 10.1021/jm00117a004
Klebsiella pneumoniae Klebsiella pneumoniae MIC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
La Crosse virus La Crosse virus EC50 70000.0 nM 10.1128/aac.00356-07
Lyssavirus rabies Lyssavirus rabies Inhibition nan % 10.1021/acsmedchemlett.9b00155
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 Activity nan None 10.1016/j.ejmech.2011.11.021
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 48.0 ug.mL-1 10.1021/jm061281+
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 112.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 200.0 ug.mL-1 10.1021/jm0707166
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 100000.0 nM 10.1016/j.bmc.2009.05.020
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 100000.0 nM 10.1021/jm060030y
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 146000.0 nM 10.1016/j.ejmech.2012.03.007
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 146000.0 nM 10.1021/jm801470b
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 174000.0 nM 10.1016/j.bmc.2011.04.016
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1007/s00044-012-0184-x
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.bmc.2012.03.004
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.bmc.2015.12.008
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.bmc.2018.05.034
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.ejmech.2009.12.002
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.ejmech.2013.05.046
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.ejmech.2013.06.036
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.ejmech.2015.06.024
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1016/j.ejmech.2017.04.070
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 250000.0 nM 10.1021/jm0614329
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 IC50 0.7 ug.mL-1 10.1021/jm0701472
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 20.0 ug.mL-1 10.1021/jm00125a024
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 20.0 ug.mL-1 10.1021/jm00369a010
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 40.0 ug.mL-1 10.1021/jm00102a010
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 70.0 ug.mL-1 10.1021/jm00128a011
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 100.0 ug.mL-1 10.1021/jm00373a020
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 300.0 ug.mL-1 10.1007/s00044-012-0127-6
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC 150000.0 nM 10.1021/jm070324z
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC50 16.0 ug.mL-1 10.1021/jm050772b
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC50 70.0 ug.mL-1 10.1021/jm950891z
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC50 75.0 ug.mL-1 10.1021/jm00386a007
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 MIC50 150.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Mammarenavirus choriomeningitidis Mammarenavirus choriomeningitidis EC50 3500.0 nM 10.1016/j.bmcl.2023.129175
Mammarenavirus juninense Junin virus EC50 2500.0 nM 10.1016/j.bmcl.2023.129175
Mammarenavirus juninense Junin virus EC50 11000.0 nM 10.1128/aac.00356-07
Mammarenavirus juninense Junin virus EC50 18500.0 nM 10.1016/j.bmcl.2018.12.063
Mammarenavirus juninense Junin virus EC50 18500.0 nM 10.1016/j.ejmech.2010.11.012
Mammarenavirus juninense Junin virus EC50 19200.0 nM 10.1016/j.bmcl.2018.12.063
Mammarenavirus lassaense Lassa virus Activity 0.0 % 10.1016/j.bmcl.2012.11.095
Mammarenavirus tacaribeense Tacaribe virus EC50 9.3 ug.mL-1 10.1016/j.bmcl.2019.08.017
Mammarenavirus tacaribeense Tacaribe virus EC50 10000.0 nM 10.1128/aac.00356-07
Mammarenavirus tacaribeense Tacaribe virus EC50 27800.0 nM 10.1016/j.bmcl.2023.129219
Mammarenavirus tacaribeense Tacaribe virus EC50 31100.0 nM 10.1016/j.bmcl.2023.129219
Mammarenavirus tacaribeense Tacaribe virus IC50 26700.0 nM 10.1016/j.bmc.2015.07.039
Measles morbillivirus Measles morbillivirus ED50 3e-05 M 10.1021/jm00148a015
Measles morbillivirus Measles morbillivirus ED50 9.9e-05 M 10.1021/jm00152a016
Measles morbillivirus Measles morbillivirus IC50 1160000.0 nM 10.1021/jm301778x
Measles morbillivirus Measles morbillivirus MIC 20.0 ug.mL-1 10.1021/jm00373a020
Measles morbillivirus Measles morbillivirus MIC 20.0 ug.mL-1 10.1021/jm00378a037
Measles morbillivirus Measles morbillivirus MIC 77.89 ug.mL-1 10.1016/j.bmc.2009.10.012
Measles morbillivirus Measles morbillivirus MIC50 30.0 ug.mL-1 10.1021/jm00386a007
Mesocricetus auratus BHK-21 CC100 160.0 ug ml-1 10.1021/acs.jnatprod.2c00464
Mesocricetus auratus BHK-21 CC50 5460.0 nM 10.1016/j.bmcl.2023.129174
Mesocricetus auratus BHK-21 EC50 1100.0 nM 10.1021/jm051229y
Mesocricetus auratus Syrian golden hamster Activity 2.4 g 10.1128/aac.01074-08
Mesocricetus auratus Syrian golden hamster LD50 217.0 mg/kg/day 10.1128/aac.00356-07
Monkeypox virus Monkeypox virus IC50 145000.0 nM 10.1016/j.bmc.2008.11.075
Murine hepatitis virus Murine hepatitis virus Activity nan None 10.1021/np50059a031
Mus musculus Adenosine A1 receptor Ki 4430.0 nM 10.1021/acs.jmedchem.8b01662
Mus musculus Adenosine A3 receptor Inhibition 0.0 % 10.1021/acs.jmedchem.8b01662
Mus musculus B16-F10 IC50 3500.0 nM 10.1016/j.ejmech.2019.112009
Mus musculus B16-F10 Inhibition 80.0 % 10.1016/j.ejmech.2019.112009
Mus musculus Ehrlich Inhibition 14.0 % 10.1021/jm00210a008
Mus musculus Ehrlich Inhibition 65.0 % 10.1021/jm00210a008
Mus musculus Equilibrative nucleoside transporter 1 Activity nan None 10.1128/aac.00010-10
Mus musculus Equilibrative nucleoside transporter 2 Activity nan None 10.1128/aac.00010-10
Mus musculus FM3A IC50 3.9 ug.mL-1 10.1021/jm00075a030
Mus musculus L1210 IC50 7.1 ug.mL-1 10.1021/jm00075a030
Mus musculus L1210 IC50 16600.0 nM 10.1016/0960-894X(96)00216-8
Mus musculus L1210 ID50 3.18 ug ml-1 10.1021/jm00369a010
Mus musculus L1210 ID50 36.0 uM 10.1021/jm00163a054
Mus musculus Mus musculus Activity 11.5 g 10.1016/j.bmcl.2007.06.049
Mus musculus Mus musculus Activity nan None 10.1016/j.bmcl.2007.06.049
Mus musculus Mus musculus Activity nan None 10.1021/acsmedchemlett.7b00188
Mus musculus Mus musculus Activity nan None 10.1021/jm00212a014
Mus musculus Mus musculus EC50 8300.0 nM 10.1021/jm00105a064
Mus musculus Mus musculus EC50 32100.0 nM 10.1021/jm00105a064
Mus musculus Mus musculus Efficacy 1.86 None 10.1016/j.bmcl.2005.11.109
Mus musculus Mus musculus IC50 52000.0 nM 10.1021/jm00105a064
Mus musculus Mus musculus LD50 220.0 mg/kg/day 10.1128/aac.00356-07
Mus musculus Mus musculus LD50 730.0 mg/kg/day 10.1128/aac.00356-07
Mus musculus Mus musculus MTC 100.0 mg kg-1 10.1021/jm00147a013
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus Sodium/nucleoside cotransporter 2 Activity nan None 10.1128/aac.00010-10
Mus musculus X5563 GI 50.0 % 10.1016/j.ejmech.2013.08.053
Mustela putorius furo Mustela putorius furo Activity -22.2 % 10.1021/jm00188a013
Mustela putorius furo Mustela putorius furo Activity -20.1 % 10.1021/jm00188a013
Mustela putorius furo Mustela putorius furo Activity -4.5 % 10.1021/jm00188a013
Nicotiana tabacum Nicotiana tabacum Activity 10.0 % 10.1021/jf902863z
Nicotiana tabacum Nicotiana tabacum Activity 28.0 % 10.1021/jf1006193
Nicotiana tabacum Nicotiana tabacum Activity 31.0 % 10.1021/jf1006193
Nicotiana tabacum Nicotiana tabacum Activity 40.0 % 10.1021/jf902863z
Nicotiana tabacum Nicotiana tabacum Activity nan None 10.1021/jf1006193
Nicotiana tabacum Nicotiana tabacum Activity nan None 10.1021/jf9029628
Orthohantavirus hantanense Orthohantavirus hantanense IC50 nan None 10.1016/j.bmcl.2021.127926
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Oryctolagus cuniculus Oryctolagus cuniculus MCC 400.0 ug.mL-1 10.1021/jm00125a024
Oryctolagus cuniculus Oryctolagus cuniculus MCC 400.0 ug.mL-1 10.1021/jm00157a016
Oryctolagus cuniculus Oryctolagus cuniculus MCC 400.0 ug.mL-1 10.1021/jm00369a010
Oryctolagus cuniculus Oryctolagus cuniculus MIC 10.0 ug.mL-1 10.1021/jm00128a011
Oryctolagus cuniculus Oryctolagus cuniculus MIC 20.0 ug.mL-1 10.1021/jm00389a005
Oryctolagus cuniculus Oryctolagus cuniculus MIC 150.0 ug.mL-1 10.1021/jm00389a005
Oryctolagus cuniculus Oryctolagus cuniculus MIC 300.0 ug.mL-1 10.1021/jm00128a011
Oryctolagus cuniculus Oryctolagus cuniculus MIC 400.0 ug.mL-1 10.1021/jm00128a011
Oryctolagus cuniculus Oryctolagus cuniculus MIC 400.0 ug.mL-1 10.1021/jm00389a005
Oryctolagus cuniculus Oryctolagus cuniculus MTC 400.0 ug ml-1 10.1021/jm00386a007
Pichinde virus Pichinde virus Activity 11.0 day 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 15.0 IU/L 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 18.0 day 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 18.3 day 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 18.5 day 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 20.0 % 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 21.0 day 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 24.0 IU/L 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 26.0 IU/L 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 30.0 IU/L 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 40.0 % 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 67.0 IU/L 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 80.0 % 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity 100.0 % 10.1128/aac.00356-07
Pichinde virus Pichinde virus Activity nan None 10.1128/aac.00356-07
Pichinde virus Pichinde virus EC50 12.0 ug.mL-1 10.1016/j.bmcl.2019.08.017
Pichinde virus Pichinde virus EC50 13000.0 nM 10.1128/aac.00356-07
Pichinde virus Pichinde virus EC50 36400.0 nM 10.1016/j.bmcl.2023.129219
Pichinde virus Pichinde virus EC50 45000.0 nM 10.1016/j.bmcl.2023.129219
Pichinde virus Pichinde virus Efficacy 60.0 % 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 3.0 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 3.2 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 3.5 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 4.2 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 5.1 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 6.0 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 6.5 None 10.1128/aac.00356-07
Pichinde virus Pichinde virus log10CCID50 6.8 None 10.1128/aac.00356-07
Plasmodium falciparum Plasmodium falciparum IC50 12589.25 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum Potency 2078.7 nM None
Plasmodium falciparum Plasmodium falciparum Potency 18526.0 nM None
Plasmodium falciparum Spermidine synthase Activity nan None 10.1021/jm7016144
Poliovirus 1 Poliovirus 1 EC50 100000.0 nM 10.1016/j.bmc.2009.05.020
Poliovirus 1 Poliovirus 1 EC50 100000.0 nM 10.1016/j.bmc.2010.02.037
Poliovirus 1 Poliovirus 1 EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Poliovirus 1 Poliovirus 1 EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
Poliovirus 1 Poliovirus 1 MIC 7.0 ug.mL-1 10.1021/jm00369a010
Poliovirus 1 Poliovirus 1 MIC 10.0 ug.mL-1 10.1021/jm00373a020
Poliovirus 1 Poliovirus 1 MIC 70.0 ug.mL-1 10.1021/jm00102a010
Poliovirus 1 Poliovirus 1 MIC50 20.0 ug.mL-1 10.1021/jm00386a007
Poliovirus 1 Poliovirus 1 MIC50 40.0 ug.mL-1 10.1021/jm00220a027
Potato virus X Potato virus X Inhibition 94.0 % 10.1021/np020169l
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 3.0 ug.mL-1 10.1021/acs.jmedchem.6b00325
Punta Toro virus Punta Toro virus Activity 0.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 4.0 day 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 5.0 day 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 5.3 day 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 13.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 13.3 day 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 20.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 21.0 day 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 38.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 40.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 60.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 70.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 80.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 100.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 131.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 450.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 846.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 1491.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 1515.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity 2150.0 IU/L 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Activity nan None 10.1016/j.ejmech.2011.11.021
Punta Toro virus Punta Toro virus Activity nan None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus EC50 40.0 ug.mL-1 10.1021/jm0707166
Punta Toro virus Punta Toro virus EC50 48.0 ug.mL-1 10.1021/jm061281+
Punta Toro virus Punta Toro virus EC50 48.0 ug.mL-1 10.1021/jm100093p
Punta Toro virus Punta Toro virus EC50 112.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Punta Toro virus Punta Toro virus EC50 146.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Punta Toro virus Punta Toro virus EC50 146.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Punta Toro virus Punta Toro virus EC50 146.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Punta Toro virus Punta Toro virus EC50 29000.0 nM 10.1016/j.ejmech.2017.04.070
Punta Toro virus Punta Toro virus EC50 50000.0 nM 10.1016/j.bmc.2015.12.008
Punta Toro virus Punta Toro virus EC50 50000.0 nM 10.1016/j.ejmech.2009.12.002
Punta Toro virus Punta Toro virus EC50 50000.0 nM 10.1016/j.ejmech.2012.03.007
Punta Toro virus Punta Toro virus EC50 50000.0 nM 10.1021/jm801470b
Punta Toro virus Punta Toro virus EC50 100000.0 nM 10.1021/jm060030y
Punta Toro virus Punta Toro virus EC50 112000.0 nM 10.1007/s00044-012-0184-x
Punta Toro virus Punta Toro virus EC50 112000.0 nM 10.1016/j.bmc.2015.04.079
Punta Toro virus Punta Toro virus EC50 112000.0 nM 10.1016/j.ejmech.2013.06.036
Punta Toro virus Punta Toro virus EC50 112000.0 nM 10.1016/j.ejmech.2015.06.024
Punta Toro virus Punta Toro virus EC50 125000.0 nM 10.1016/j.bmc.2011.04.016
Punta Toro virus Punta Toro virus EC50 126000.0 nM 10.1016/j.bmc.2012.03.004
Punta Toro virus Punta Toro virus EC50 126000.0 nM 10.1016/j.bmc.2018.05.034
Punta Toro virus Punta Toro virus EC50 126000.0 nM 10.1016/j.ejmech.2013.05.046
Punta Toro virus Punta Toro virus EC50 126000.0 nM 10.1039/c1md00094b
Punta Toro virus Punta Toro virus EC50 146000.0 nM 10.1007/s00044-009-9248-y
Punta Toro virus Punta Toro virus EC50 150000.0 nM 10.1016/j.ejmech.2015.08.008
Punta Toro virus Punta Toro virus EC50 150000.0 nM 10.1021/jm0614329
Punta Toro virus Punta Toro virus EC50 172000.0 nM 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus EC50 183000.0 nM 10.1016/j.bmc.2010.02.015
Punta Toro virus Punta Toro virus IC50 20.0 ug.mL-1 10.1021/jm0701472
Punta Toro virus Punta Toro virus ID50 20.1 ug ml-1 10.1021/jm00117a004
Punta Toro virus Punta Toro virus log10CCID50 2.8 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 2.9 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 3.1 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 3.3 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 4.2 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 4.9 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 5.0 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 5.9 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 6.1 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus log10CCID50 6.7 None 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Punta Toro virus Punta Toro virus MIC 60.0 ug.mL-1 10.1007/s00044-012-0127-6
Punta Toro virus Punta Toro virus MIC 250000.0 nM 10.1021/jm070324z
Punta Toro virus Punta Toro virus MIC 300000.0 nM 10.1016/j.bmc.2006.10.046
Punta Toro virus Punta Toro virus MIC50 80.0 ug.mL-1 10.1021/jm050772b
Punta Toro virus Punta Toro virus MIC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Punta Toro virus Punta Toro virus Survival 10.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Survival 70.0 % 10.1128/aac.00356-07
Punta Toro virus Punta Toro virus Virus rating 1.8 None 10.1021/jm00117a004
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus C6 IC50 13510.0 nM 10.1016/j.ejmech.2019.112009
Rattus norvegicus C6 Inhibition 75.0 % 10.1016/j.ejmech.2019.112009
Rattus norvegicus Cyclooxygenase-1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Equilibrative nucleoside transporter 1 Activity nan None 10.1128/aac.00010-10
Rattus norvegicus Equilibrative nucleoside transporter 2 Activity nan None 10.1128/aac.00010-10
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Muscarinic acetylcholine receptor M1 Potency 50.1 nM None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Rattus norvegicus ALB 31700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 36300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 37000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 43700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 195.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 197.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 293.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 347.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 371.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 380.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 390.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 34.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 43.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 48.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 50.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 53.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 55.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 185.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 75.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 82.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 89.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 93.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 117.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 225.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 480.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 133.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 136.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 148.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 150.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 153.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 163.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.83 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 101.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 104.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 107.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 113.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 606.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 630.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 656.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 713.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 725.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 830.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 880.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 230.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 286.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 441.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 503.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 1121.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 1211.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 1322.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 16000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 20000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 24830000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 26000000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 27170000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 27670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.6 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.9 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 21.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 33.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 40.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 179.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 216.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 2.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1460.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1533.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1576.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1603.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1630.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1710.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 2116.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 34.3 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.35 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.53 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 39.37 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 39.7 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 40.57 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 127700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 134700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 140500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 144000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 148000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 153700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 157700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 88.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 189.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 257.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 316.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 427.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 634.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 651.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 7.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 8.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 14.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 35.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 6405.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9535.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10736.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13109.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 13599.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 14288.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 17320.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 80.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 81.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 82.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 91.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 92.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.47 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.53 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 23.67 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.62 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.7 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.72 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.77 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 373000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 378700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 385300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 386500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 392300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 394300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 400700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 60.97 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 61.7 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.53 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.68 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.87 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.2 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.7 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 112.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 126.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 205.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 239.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 316.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 7.17 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 7.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 7.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 15.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 17.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 18.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 968.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1021.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1164.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1397.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1482.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1715.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 2451.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 115.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 116.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 116.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 133.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 140.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 148.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 170.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1066330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1071000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1225500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1248670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1269330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1280500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1365670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.16 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.69 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.86 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.94 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.1 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 7.12 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 44700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 52000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 53300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 60000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 61200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5440000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5460000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5710000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5830000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6280000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6370000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6480000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.17 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.33 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.62 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.93 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 145.03 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 147.03 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 148.0 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 151.47 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 15.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 16.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 18.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 19.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 26.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 30.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 47.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 8000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11470.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 13370.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 14430.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 14900.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 15480.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 19030.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Sodium/nucleoside cotransporter 1 Activity nan None 10.1128/aac.00010-10
Rattus norvegicus Sodium/nucleoside cotransporter 2 Activity nan None 10.1128/aac.00010-10
Rattus norvegicus Synaptic vesicular amine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Reovirus sp. Reovirus sp. EC50 80.0 ug.mL-1 10.1021/jm100093p
Reovirus sp. Reovirus sp. EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Reovirus sp. Reovirus sp. EC50 250000.0 nM 10.1007/s00044-009-9248-y
Reovirus sp. Reovirus sp. MIC 40.0 ug.mL-1 10.1021/jm00378a037
Respiratory syncytial virus Respiratory syncytial virus Activity 0.3 % 10.1016/j.ejmech.2021.113684
Respiratory syncytial virus Respiratory syncytial virus Activity 7.6 % 10.1016/j.ejmech.2021.113684
Respiratory syncytial virus Respiratory syncytial virus Activity nan None 10.1016/j.ejmech.2011.11.021
Respiratory syncytial virus Respiratory syncytial virus Activity nan None 10.1016/j.ejmech.2021.113684
Respiratory syncytial virus Respiratory syncytial virus EC50 1.8 ug.mL-1 10.1021/np9601871
Respiratory syncytial virus Respiratory syncytial virus EC50 1.8 ug.mL-1 10.1021/np9703914
Respiratory syncytial virus Respiratory syncytial virus EC50 1.8 ug.mL-1 10.1021/np980086y
Respiratory syncytial virus Respiratory syncytial virus EC50 2.2 ug.mL-1 10.1021/np9703914
Respiratory syncytial virus Respiratory syncytial virus EC50 2.3 ug.mL-1 10.1021/np9703914
Respiratory syncytial virus Respiratory syncytial virus EC50 2.8 ug.mL-1 10.1016/j.ejmech.2010.09.065
Respiratory syncytial virus Respiratory syncytial virus EC50 3.6 ug.mL-1 10.1021/np060398y
Respiratory syncytial virus Respiratory syncytial virus EC50 6.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Respiratory syncytial virus Respiratory syncytial virus EC50 10.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Respiratory syncytial virus Respiratory syncytial virus EC50 10.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Respiratory syncytial virus Respiratory syncytial virus EC50 16.0 ug.mL-1 10.1021/jm061281+
Respiratory syncytial virus Respiratory syncytial virus EC50 16.0 ug.mL-1 10.1021/jm100093p
Respiratory syncytial virus Respiratory syncytial virus EC50 20.0 ug.mL-1 10.1021/np060398y
Respiratory syncytial virus Respiratory syncytial virus EC50 22.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Respiratory syncytial virus Respiratory syncytial virus EC50 24.0 ug.mL-1 10.1021/jm0707166
Respiratory syncytial virus Respiratory syncytial virus EC50 2000.0 nM 10.1016/j.ejmech.2021.113467
Respiratory syncytial virus Respiratory syncytial virus EC50 3000.0 nM 10.1016/j.bmc.2011.04.016
Respiratory syncytial virus Respiratory syncytial virus EC50 4600.0 nM 10.1007/s00044-012-0184-x
Respiratory syncytial virus Respiratory syncytial virus EC50 5000.0 nM 10.1016/j.ejmech.2013.05.046
Respiratory syncytial virus Respiratory syncytial virus EC50 5000.0 nM 10.1016/j.ejmech.2013.06.036
Respiratory syncytial virus Respiratory syncytial virus EC50 5400.0 nM 10.1021/acs.jnatprod.2c00766
Respiratory syncytial virus Respiratory syncytial virus EC50 5800.0 nM 10.1016/j.ejmech.2017.04.070
Respiratory syncytial virus Respiratory syncytial virus EC50 5800.0 nM 10.1016/j.ejmech.2018.05.059
Respiratory syncytial virus Respiratory syncytial virus EC50 6600.0 nM 10.1016/j.ejmech.2010.03.002
Respiratory syncytial virus Respiratory syncytial virus EC50 7000.0 nM 10.1016/j.bmc.2009.05.020
Respiratory syncytial virus Respiratory syncytial virus EC50 7000.0 nM 10.1016/j.bmc.2010.02.037
Respiratory syncytial virus Respiratory syncytial virus EC50 7000.0 nM 10.1016/j.bmc.2014.06.043
Respiratory syncytial virus Respiratory syncytial virus EC50 10000.0 nM 10.1007/s00044-009-9248-y
Respiratory syncytial virus Respiratory syncytial virus EC50 10000.0 nM 10.1016/j.bmc.2012.03.004
Respiratory syncytial virus Respiratory syncytial virus EC50 10000.0 nM 10.1021/jm801470b
Respiratory syncytial virus Respiratory syncytial virus EC50 10000.0 nM 10.1039/c1md00094b
Respiratory syncytial virus Respiratory syncytial virus EC50 10800.0 nM 10.1039/d3md00055a
Respiratory syncytial virus Respiratory syncytial virus EC50 11500.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 12000.0 nM 10.1021/jm060030y
Respiratory syncytial virus Respiratory syncytial virus EC50 13300.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 15000.0 nM 10.1007/s00044-010-9533-9
Respiratory syncytial virus Respiratory syncytial virus EC50 15000.0 nM 10.1016/j.bmc.2015.12.008
Respiratory syncytial virus Respiratory syncytial virus EC50 15830.0 nM 10.1016/j.ejmech.2019.111861
Respiratory syncytial virus Respiratory syncytial virus EC50 16800.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 17600.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 18530.0 nM 10.1016/j.ejmech.2021.113684
Respiratory syncytial virus Respiratory syncytial virus EC50 19000.0 nM 10.1016/j.bmc.2010.02.015
Respiratory syncytial virus Respiratory syncytial virus EC50 19000.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 20700.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 25000.0 nM 10.1016/j.bmc.2018.05.034
Respiratory syncytial virus Respiratory syncytial virus EC50 25300.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 28400.0 nM 10.1021/jm300612z
Respiratory syncytial virus Respiratory syncytial virus EC50 29000.0 nM 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus EC50 30000.0 nM 10.1016/j.ejmech.2009.12.002
Respiratory syncytial virus Respiratory syncytial virus EC50 35000.0 nM 10.1016/j.bmcl.2015.04.006
Respiratory syncytial virus Respiratory syncytial virus EC50 250000.0 nM 10.1016/j.ejmech.2012.03.007
Respiratory syncytial virus Respiratory syncytial virus EC50 nan None 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus FC 0.85 None 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus FC 2.5 None 10.1021/jm300612z
Respiratory syncytial virus Respiratory syncytial virus FC nan None 10.1128/aac.00211-07
Respiratory syncytial virus Respiratory syncytial virus IC50 2.0 ug.mL-1 10.1021/jm0701472
Respiratory syncytial virus Respiratory syncytial virus IC50 2.6 ug.mL-1 10.1021/np030470h
Respiratory syncytial virus Respiratory syncytial virus IC50 3.0 ug.mL-1 10.1021/np050498o
Respiratory syncytial virus Respiratory syncytial virus IC50 80.0 nM 10.1016/j.ejmech.2020.112790
Respiratory syncytial virus Respiratory syncytial virus IC50 180.0 ug.mL-1 10.1021/np060398y
Respiratory syncytial virus Respiratory syncytial virus IC50 460.0 ug.mL-1 10.1021/np060398y
Respiratory syncytial virus Respiratory syncytial virus IC50 10700.0 nM 10.1021/np800542t
Respiratory syncytial virus Respiratory syncytial virus IC50 17330.0 nM 10.1016/j.ejmech.2021.113208
Respiratory syncytial virus Respiratory syncytial virus IC50 19000.0 nM 10.1021/acs.jnatprod.2c00322
Respiratory syncytial virus Respiratory syncytial virus IC50 20000.0 nM 10.1021/np500650t
Respiratory syncytial virus Respiratory syncytial virus IC50 20400.0 nM 10.1021/np500252q
Respiratory syncytial virus Respiratory syncytial virus Inhibition nan % 10.1016/j.ejmech.2021.113684
Respiratory syncytial virus Respiratory syncytial virus MIC 9.6 ug.mL-1 10.1016/j.ejmech.2007.04.010
Respiratory syncytial virus Respiratory syncytial virus MIC 60.0 ug.mL-1 10.1007/s00044-012-0127-6
Respiratory syncytial virus Respiratory syncytial virus MIC 60000.0 nM 10.1021/np060435l
Respiratory syncytial virus Respiratory syncytial virus MIC 150000.0 nM 10.1021/jm070324z
Respiratory syncytial virus Respiratory syncytial virus MIC50 9.6 ug.mL-1 10.1021/jm050772b
Respiratory syncytial virus Respiratory syncytial virus MIC50 50.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Respiratory syncytial virus Respiratory syncytial virus RFU 0.04 None 10.1016/j.ejmech.2019.111861
Respiratory syncytial virus Respiratory syncytial virus TIME 7.0 hr 10.1021/jm300612z
Respirovirus muris Respirovirus muris EC50 250000.0 nM 10.1007/s00044-012-0184-x
Rift Valley fever virus Rift Valley fever virus Activity nan None 10.1021/np50055a001
Rift Valley fever virus Rift Valley fever virus EC50 49000.0 nM 10.1016/j.bmcl.2023.129219
Rift Valley fever virus Rift Valley fever virus EC50 53000.0 nM 10.1016/j.bmcl.2023.129219
Rift Valley fever virus Rift Valley fever virus EC50 53000.0 nM 10.1128/aac.00356-07
Rift Valley fever virus Rift Valley fever virus ED50 1.1 M 10.1021/jm00147a013
Rift Valley fever virus Rift Valley fever virus IC50 37300.0 nM 10.1016/j.bmc.2015.07.039
Rift Valley fever virus Rift Valley fever virus ILS 70.0 % 10.1021/jm00140a006
Sandfly fever Naples virus Sandfly fever Naples virus EC50 90000.0 nM 10.1128/aac.00356-07
Sandfly fever Sicilian virus Sandfly fever Sicilian virus Activity nan None 10.1021/np50055a001
Semliki Forest virus Semliki Forest virus Activity nan None 10.1021/np9003245
Semliki Forest virus Semliki Forest virus IC50 95100.0 nM 10.1021/np9003245
Semliki Forest virus Semliki Forest virus IC50 95499.26 nM 10.1021/np9003245
Semliki Forest virus Semliki Forest virus MIC 150.0 ug.mL-1 10.1021/jm00125a024
Semliki Forest virus Semliki Forest virus MIC 200.0 ug.mL-1 10.1021/jm00102a010
Semliki Forest virus Semliki Forest virus MIC 300.0 ug.mL-1 10.1021/jm00128a011
Semliki Forest virus Semliki Forest virus MIC50 400.0 ug.mL-1 10.1021/jm950891z
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 10.13 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Activity nan None 10.1038/s41586-020-2286-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 AUC 248.7 None 10.1038/s41586-020-2286-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 109500.0 nM 10.1016/j.ejmech.2020.112559
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 109500.0 nM 10.1016/j.ejmech.2020.112862
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 109500.0 nM 10.1021/acs.jmedchem.0c00606
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 109500.0 nM 10.1021/acs.jmedchem.0c01746
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 10950000.0 nM 10.1016/j.bmc.2020.115757
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 nan None 10.1016/j.bmcl.2023.129174
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.1047 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.2922 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 50100.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 50118.72 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 81470.43 nM 10.1038/s41586-020-2286-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 109500.0 nM 10.1016/j.ejmech.2021.113683
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 109500.0 nM 10.1021/acs.jmedchem.0c00626
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 nan None 10.1016/j.ejmech.2021.113683
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.06 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 11.83 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.527 None 10.1101/2020.04.03.023846
Severe acute respiratory syndrome-related coronavirus SARS-CoV EC50 100000.0 nM 10.1016/j.ejmech.2020.112687
Severe acute respiratory syndrome-related coronavirus SARS-CoV EC50 109500.0 nM 10.1016/j.ejmech.2021.113157
Severe acute respiratory syndrome-related coronavirus SARS-CoV IC50 82000.0 nM 10.1016/j.bmcl.2007.02.026
Severe acute respiratory syndrome-related coronavirus SARS-CoV INH 500.0 ug ml-1 10.1016/j.bmcl.2015.05.039
Sigmodon Cotton rat Efficacy 2.5 None 10.1016/j.bmcl.2005.11.109
Sindbis virus Sindbis virus Activity nan None 10.1016/j.ejmech.2011.11.021
Sindbis virus Sindbis virus EC50 120.0 ug.mL-1 10.1021/jm0707166
Sindbis virus Sindbis virus EC50 240.0 ug.mL-1 10.1021/jm061281+
Sindbis virus Sindbis virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Sindbis virus Sindbis virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Sindbis virus Sindbis virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Sindbis virus Sindbis virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Sindbis virus Sindbis virus EC50 400.0 ug.mL-1 10.1021/jm100093p
Sindbis virus Sindbis virus EC50 5120.0 nM 10.1021/acs.jmedchem.5b01047
Sindbis virus Sindbis virus EC50 50000.0 nM 10.1021/jm0614329
Sindbis virus Sindbis virus EC50 111000.0 nM 10.1016/j.ejmech.2009.12.002
Sindbis virus Sindbis virus EC50 148100.0 nM 10.1039/d3md00055a
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1007/s00044-009-9248-y
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.bmc.2011.04.016
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.bmc.2012.03.004
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.bmc.2015.12.008
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.bmc.2018.05.034
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.ejmech.2012.03.007
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.ejmech.2013.05.046
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.ejmech.2013.06.036
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.ejmech.2015.06.024
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.ejmech.2015.08.008
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1016/j.ejmech.2017.04.070
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1021/jm801470b
Sindbis virus Sindbis virus EC50 250000.0 nM 10.1039/c1md00094b
Sindbis virus Sindbis virus EC50 500000.0 nM 10.1021/jm060030y
Sindbis virus Sindbis virus MIC 40.0 ug.mL-1 10.1021/jm00373a020
Sindbis virus Sindbis virus MIC 40.0 ug.mL-1 10.1021/jm00378a037
Sindbis virus Sindbis virus MIC 70.0 ug.mL-1 10.1021/jm00125a024
Sindbis virus Sindbis virus MIC 70.0 ug.mL-1 10.1021/jm00128a011
Sindbis virus Sindbis virus MIC 150.0 ug.mL-1 10.1021/jm00369a010
Sindbis virus Sindbis virus MIC 200.0 ug.mL-1 10.1021/jm00102a010
Sindbis virus Sindbis virus MIC 240.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Sindbis virus Sindbis virus MIC 300.0 ug.mL-1 10.1007/s00044-012-0127-6
Sindbis virus Sindbis virus MIC 100000.0 nM 10.1016/j.bmc.2006.10.046
Sindbis virus Sindbis virus MIC 250000.0 nM 10.1021/jm070324z
Sindbis virus Sindbis virus MIC50 65.0 ug.mL-1 10.1021/jm00386a007
Sindbis virus Sindbis virus MIC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Sindbis virus Sindbis virus MIC50 400.0 ug.mL-1 10.1021/jm050772b
Sindbis virus Sindbis virus MIC50 400.0 ug.mL-1 10.1021/jm950891z
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1021/jm00199a015
Staphylococcus hominis Staphylococcus hominis MIC 400.0 ug.mL-1 10.1016/s0960-894x(01)00838-1
Streptococcus pyogenes Streptococcus pyogenes MIC nan None 10.1021/jm00199a015
Suid alphaherpesvirus 1 Suid alphaherpesvirus 1 Activity 16.0 mM 10.1016/S0960-894X(01)80822-2
Suid alphaherpesvirus 1 Suid alphaherpesvirus 1 Activity 40.0 mM 10.1016/S0960-894X(01)80822-2
Suid alphaherpesvirus 1 Suid alphaherpesvirus 1 Activity 47.0 mM 10.1016/S0960-894X(01)80822-2
Tobacco mosaic virus Tobacco mosaic virus Activity 7.5 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Activity 8.2 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Activity 9.8 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Activity 14.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Activity 30.0 % 10.1021/jf1006193
Tobacco mosaic virus Tobacco mosaic virus Activity 32.1 % 10.1021/jf302746m
Tobacco mosaic virus Tobacco mosaic virus Activity 32.7 % 10.1016/j.ejmech.2012.04.010
Tobacco mosaic virus Tobacco mosaic virus Activity 32.7 % 10.1016/j.ejmech.2012.04.020
Tobacco mosaic virus Tobacco mosaic virus Activity 33.8 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Activity 34.2 % 10.1016/j.ejmech.2012.04.010
Tobacco mosaic virus Tobacco mosaic virus Activity 34.2 % 10.1016/j.ejmech.2012.04.020
Tobacco mosaic virus Tobacco mosaic virus Activity 34.2 % 10.1021/jf302746m
Tobacco mosaic virus Tobacco mosaic virus Activity 34.5 % 10.1021/jf302746m
Tobacco mosaic virus Tobacco mosaic virus Activity 36.7 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Activity 38.9 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Activity 39.0 % 10.1016/j.bmcl.2010.10.141
Tobacco mosaic virus Tobacco mosaic virus Activity 39.6 % 10.1016/j.ejmech.2012.04.010
Tobacco mosaic virus Tobacco mosaic virus Activity 39.6 % 10.1016/j.ejmech.2012.04.020
Tobacco mosaic virus Tobacco mosaic virus Activity 40.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Activity 44.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Activity 46.0 % 10.1021/jf1006193
Tobacco mosaic virus Tobacco mosaic virus Activity 46.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Activity 49.0 % 10.1016/j.bmcl.2006.02.023
Tobacco mosaic virus Tobacco mosaic virus Activity 57.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Activity 59.0 % 10.1021/jf1006193
Tobacco mosaic virus Tobacco mosaic virus Activity 71.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Activity nan None 10.1021/jf1006193
Tobacco mosaic virus Tobacco mosaic virus GI 38.5 % 10.1021/jf302746m
Tobacco mosaic virus Tobacco mosaic virus IC50 2989600.0 nM 10.1021/np0702077
Tobacco mosaic virus Tobacco mosaic virus Inhibition 7.5 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 8.2 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 9.8 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 11.9 % 10.1016/j.ejmech.2019.02.002
Tobacco mosaic virus Tobacco mosaic virus Inhibition 12.5 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Inhibition 16.7 % 10.1021/jf9029628
Tobacco mosaic virus Tobacco mosaic virus Inhibition 19.6 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 20.0 % 10.1021/jf1006193
Tobacco mosaic virus Tobacco mosaic virus Inhibition 21.62 % 10.1021/jf9029628
Tobacco mosaic virus Tobacco mosaic virus Inhibition 28.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Inhibition 32.0 % 10.1021/jf1006193
Tobacco mosaic virus Tobacco mosaic virus Inhibition 33.8 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 36.7 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 37.6 % 10.1016/j.ejmech.2019.02.002
Tobacco mosaic virus Tobacco mosaic virus Inhibition 37.93 % 10.1021/jf9029628
Tobacco mosaic virus Tobacco mosaic virus Inhibition 38.0 % 10.1021/jf902863z
Tobacco mosaic virus Tobacco mosaic virus Inhibition 38.5 % 10.1016/j.ejmech.2012.04.010
Tobacco mosaic virus Tobacco mosaic virus Inhibition 38.5 % 10.1016/j.ejmech.2012.04.020
Tobacco mosaic virus Tobacco mosaic virus Inhibition 38.9 % 10.1021/jf3013376
Tobacco mosaic virus Tobacco mosaic virus Inhibition 40.0 % 10.1021/jf303550a
Tobacco mosaic virus Tobacco mosaic virus Inhibition 41.0 % 10.1021/jf3013376
unidentified adenovirus unidentified adenovirus Activity nan None 10.1021/jm00126a027
unidentified adenovirus unidentified adenovirus EC50 27.8 ug.mL-1 10.1016/j.bmcl.2013.07.023
unidentified influenza virus unidentified influenza virus ID50 18.7 ug ml-1 10.1021/jm00117a004
unidentified influenza virus unidentified influenza virus MIC 6.0 ug.mL-1 10.1016/j.ejmech.2018.08.023
unidentified influenza virus unidentified influenza virus MIC50 14.0 ug.mL-1 10.1021/jm00389a019
unidentified influenza virus unidentified influenza virus MIC50 54.0 ug.mL-1 10.1021/jm00389a019
unidentified influenza virus unidentified influenza virus Virus rating 3.6 None 10.1021/jm00117a004
unidentified influenza virus unidentified influenza virus VR 2.6 None 10.1021/jm00389a019
unidentified influenza virus unidentified influenza virus VR 2.9 None 10.1021/jm00389a019
Vaccinia virus Vaccinia virus Activity nan None 10.1016/j.ejmech.2011.11.021
Vaccinia virus Vaccinia virus Activity nan None 10.1021/jm00206a005
Vaccinia virus Vaccinia virus Activity nan None 10.1021/jm00210a008
Vaccinia virus Vaccinia virus EC50 10.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Vaccinia virus Vaccinia virus EC50 20.0 ug.mL-1 10.1021/jm0701472
Vaccinia virus Vaccinia virus EC50 48.0 ug.mL-1 10.1021/jm100093p
Vaccinia virus Vaccinia virus EC50 146.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Vaccinia virus Vaccinia virus EC50 240.0 ug.mL-1 10.1021/jm025569k
Vaccinia virus Vaccinia virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Vaccinia virus Vaccinia virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Vaccinia virus Vaccinia virus EC50 85000.0 nM 10.1016/j.ejmech.2009.12.002
Vaccinia virus Vaccinia virus EC50 100000.0 nM 10.1016/j.bmc.2010.02.037
Vaccinia virus Vaccinia virus EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Vaccinia virus Vaccinia virus EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
Vaccinia virus Vaccinia virus EC50 100000.0 nM 10.1021/jm060030y
Vaccinia virus Vaccinia virus EC50 112000.0 nM 10.1016/j.bmc.2010.02.015
Vaccinia virus Vaccinia virus EC50 112000.0 nM 10.1021/jm801470b
Vaccinia virus Vaccinia virus EC50 146000.0 nM 10.1007/s00044-009-9248-y
Vaccinia virus Vaccinia virus EC50 250000.0 nM 10.1016/j.bmc.2012.03.004
Vaccinia virus Vaccinia virus EC50 250000.0 nM 10.1016/j.ejmech.2010.12.017
Vaccinia virus Vaccinia virus EC50 250000.0 nM 10.1039/c1md00094b
Vaccinia virus Vaccinia virus ED50 8.5e-05 M 10.1021/jm00148a015
Vaccinia virus Vaccinia virus ED50 9e-05 M 10.1021/jm00152a016
Vaccinia virus Vaccinia virus ED50 9.0 M 10.1021/jm00147a013
Vaccinia virus Vaccinia virus IC50 281000.0 nM 10.1016/j.bmc.2008.11.075
Vaccinia virus Vaccinia virus MCC 400.0 ug.mL-1 10.1021/jm00130a024
Vaccinia virus Vaccinia virus MIC 2.0 ug.mL-1 10.1021/jm00125a024
Vaccinia virus Vaccinia virus MIC 7.0 ug.mL-1 10.1021/jm00130a024
Vaccinia virus Vaccinia virus MIC 10.0 ug.mL-1 10.1021/jm00167a011
Vaccinia virus Vaccinia virus MIC 10.0 ug.mL-1 10.1021/jm00369a010
Vaccinia virus Vaccinia virus MIC 20.0 ug.mL-1 10.1021/jm00130a024
Vaccinia virus Vaccinia virus MIC 20.0 ug.mL-1 10.1021/jm00373a020
Vaccinia virus Vaccinia virus MIC 28.0 ug.mL-1 10.1021/jm00045a025
Vaccinia virus Vaccinia virus MIC 30.0 ug.mL-1 10.1021/jm00102a010
Vaccinia virus Vaccinia virus MIC 30.0 ug.mL-1 10.1021/jm00157a016
Vaccinia virus Vaccinia virus MIC 40.0 ug.mL-1 10.1021/jm00378a037
Vaccinia virus Vaccinia virus MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Vaccinia virus Vaccinia virus MIC 70.0 ug.mL-1 10.1021/jm00035a010
Vaccinia virus Vaccinia virus MIC 70.0 ug.mL-1 10.1021/jm00130a024
Vaccinia virus Vaccinia virus MIC 300.0 ug.mL-1 10.1007/s00044-012-0127-6
Vaccinia virus Vaccinia virus MIC 100000.0 nM 10.1016/j.bmc.2006.10.046
Vaccinia virus Vaccinia virus MIC 150000.0 nM 10.1021/jm070324z
Vaccinia virus Vaccinia virus MIC50 20.0 ug.mL-1 10.1021/jm00220a027
Vaccinia virus Vaccinia virus MIC50 20.0 ug.mL-1 10.1021/jm00386a007
Vaccinia virus Vaccinia virus MIC50 20.0 ug.mL-1 10.1021/jm950891z
Vaccinia virus Vaccinia virus MIC50 80.0 ug.mL-1 10.1021/jm050772b
Vaccinia virus Vaccinia virus MIC50 150.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Vaccinia virus Vaccinia virus Virus rating 1.2 None 10.1021/jm00377a002
Venezuelan equine encephalitis virus Venezuelan equine encephalitis virus Activity nan None 10.1021/np50055a001
Venezuelan equine encephalitis virus Venezuelan equine encephalitis virus ED50 2.5 M 10.1021/jm00147a013
Vesicular stomatitis Indiana virus Vesicular stomatitis Indiana virus EC50 13.7 ug.mL-1 10.1021/np020234r
Vesicular stomatitis virus Vesicular stomatitis virus Activity nan None 10.1016/j.ejmech.2011.11.021
Vesicular stomatitis virus Vesicular stomatitis virus Activity nan None 10.1016/j.ejmech.2021.113738
Vesicular stomatitis virus Vesicular stomatitis virus Activity nan None 10.1021/np50070a001
Vesicular stomatitis virus Vesicular stomatitis virus CPE50 15.0 ug ml-1 10.1021/jm00383a027
Vesicular stomatitis virus Vesicular stomatitis virus EC50 0.08 ug.mL-1 10.1016/j.bmcl.2008.12.103
Vesicular stomatitis virus Vesicular stomatitis virus EC50 3.6 ug.mL-1 10.1016/j.ejmech.2010.09.065
Vesicular stomatitis virus Vesicular stomatitis virus EC50 10.0 ug.mL-1 10.1016/0960-894X(95)00270-4
Vesicular stomatitis virus Vesicular stomatitis virus EC50 10.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Vesicular stomatitis virus Vesicular stomatitis virus EC50 10.32 ug.mL-1 10.1016/j.bmc.2006.09.066
Vesicular stomatitis virus Vesicular stomatitis virus EC50 15.62 ug.mL-1 10.1016/s0960-894x(02)00182-8
Vesicular stomatitis virus Vesicular stomatitis virus EC50 22.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Vesicular stomatitis virus Vesicular stomatitis virus EC50 24.0 ug.mL-1 10.1021/jm0707166
Vesicular stomatitis virus Vesicular stomatitis virus EC50 29.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Vesicular stomatitis virus Vesicular stomatitis virus EC50 29.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Vesicular stomatitis virus Vesicular stomatitis virus EC50 48.0 ug.mL-1 10.1021/jm100093p
Vesicular stomatitis virus Vesicular stomatitis virus EC50 80.0 ug.mL-1 10.1021/jm061281+
Vesicular stomatitis virus Vesicular stomatitis virus EC50 120.0 ug.mL-1 10.1021/jm0707166
Vesicular stomatitis virus Vesicular stomatitis virus EC50 146.0 ug.mL-1 10.1016/j.ejmech.2008.08.010
Vesicular stomatitis virus Vesicular stomatitis virus EC50 146.0 ug.mL-1 10.1016/j.ejmech.2010.07.058
Vesicular stomatitis virus Vesicular stomatitis virus EC50 240.0 ug.mL-1 10.1021/jm061281+
Vesicular stomatitis virus Vesicular stomatitis virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2009.03.038
Vesicular stomatitis virus Vesicular stomatitis virus EC50 250.0 ug.mL-1 10.1016/j.ejmech.2010.09.065
Vesicular stomatitis virus Vesicular stomatitis virus EC50 400.0 ug.mL-1 10.1021/jm025569k
Vesicular stomatitis virus Vesicular stomatitis virus EC50 400.0 ug.mL-1 10.1021/jm100093p
Vesicular stomatitis virus Vesicular stomatitis virus EC50 5000.0 nM 10.1016/j.ejmech.2013.06.036
Vesicular stomatitis virus Vesicular stomatitis virus EC50 10000.0 nM 10.1016/j.ejmech.2009.12.002
Vesicular stomatitis virus Vesicular stomatitis virus EC50 12100.0 nM 10.1007/s00044-012-0184-x
Vesicular stomatitis virus Vesicular stomatitis virus EC50 14800.0 nM 10.1016/j.bmc.2011.04.016
Vesicular stomatitis virus Vesicular stomatitis virus EC50 17000.0 nM 10.1016/j.bmc.2014.05.020
Vesicular stomatitis virus Vesicular stomatitis virus EC50 17200.0 nM 10.1016/j.ejmech.2010.03.002
Vesicular stomatitis virus Vesicular stomatitis virus EC50 22000.0 nM 10.1016/j.bmc.2010.02.015
Vesicular stomatitis virus Vesicular stomatitis virus EC50 22000.0 nM 10.1016/j.ejmech.2015.06.024
Vesicular stomatitis virus Vesicular stomatitis virus EC50 22000.0 nM 10.1021/jm801470b
Vesicular stomatitis virus Vesicular stomatitis virus EC50 23000.0 nM 10.1016/j.bmc.2015.12.008
Vesicular stomatitis virus Vesicular stomatitis virus EC50 29000.0 nM 10.1007/s00044-009-9248-y
Vesicular stomatitis virus Vesicular stomatitis virus EC50 29000.0 nM 10.1016/j.bmc.2012.03.004
Vesicular stomatitis virus Vesicular stomatitis virus EC50 29000.0 nM 10.1016/j.ejmech.2013.05.046
Vesicular stomatitis virus Vesicular stomatitis virus EC50 29000.0 nM 10.1039/c1md00094b
Vesicular stomatitis virus Vesicular stomatitis virus EC50 50000.0 nM 10.1016/j.ejmech.2017.04.070
Vesicular stomatitis virus Vesicular stomatitis virus EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Vesicular stomatitis virus Vesicular stomatitis virus EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
Vesicular stomatitis virus Vesicular stomatitis virus EC50 125000.0 nM 10.1021/jm801470b
Vesicular stomatitis virus Vesicular stomatitis virus EC50 146000.0 nM 10.1016/j.bmc.2012.03.004
Vesicular stomatitis virus Vesicular stomatitis virus EC50 146000.0 nM 10.1016/j.bmc.2018.05.034
Vesicular stomatitis virus Vesicular stomatitis virus EC50 146000.0 nM 10.1039/c1md00094b
Vesicular stomatitis virus Vesicular stomatitis virus EC50 250000.0 nM 10.1007/s00044-009-9248-y
Vesicular stomatitis virus Vesicular stomatitis virus EC50 250000.0 nM 10.1016/j.ejmech.2009.12.002
Vesicular stomatitis virus Vesicular stomatitis virus EC50 250000.0 nM 10.1016/j.ejmech.2012.03.007
Vesicular stomatitis virus Vesicular stomatitis virus EC50 500000.0 nM 10.1021/jm060030y
Vesicular stomatitis virus Vesicular stomatitis virus EC50 nan None 10.1016/j.bmc.2011.04.016
Vesicular stomatitis virus Vesicular stomatitis virus IC50 20.0 ug.mL-1 10.1021/jm0701472
Vesicular stomatitis virus Vesicular stomatitis virus IC50 nan None 10.1016/j.bmcl.2021.127926
Vesicular stomatitis virus Vesicular stomatitis virus MIC 4.0 ug.mL-1 10.1021/jm00369a010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 4.0 ug.mL-1 10.1021/jm00378a037
Vesicular stomatitis virus Vesicular stomatitis virus MIC 20.0 ug.mL-1 10.1021/jm00102a010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 20.0 ug.mL-1 10.1021/jm00373a020
Vesicular stomatitis virus Vesicular stomatitis virus MIC 40.0 ug.mL-1 10.1021/jm00378a037
Vesicular stomatitis virus Vesicular stomatitis virus MIC 48.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 50.0 ug.mL-1 10.1021/jm00102a010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 60.0 ug.mL-1 10.1007/s00044-012-0127-6
Vesicular stomatitis virus Vesicular stomatitis virus MIC 70.0 ug.mL-1 10.1021/jm00369a010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 200.0 ug.mL-1 10.1021/jm00157a016
Vesicular stomatitis virus Vesicular stomatitis virus MIC 240.0 ug.mL-1 10.1016/j.ejmech.2007.04.010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 300.0 ug.mL-1 10.1021/jm00167a011
Vesicular stomatitis virus Vesicular stomatitis virus MIC 400.0 ug.mL-1 10.1021/jm00035a010
Vesicular stomatitis virus Vesicular stomatitis virus MIC 400.0 ug.mL-1 10.1021/jm00130a024
Vesicular stomatitis virus Vesicular stomatitis virus MIC 500.0 ug.mL-1 10.1007/s00044-012-0127-6
Vesicular stomatitis virus Vesicular stomatitis virus MIC 100000.0 nM 10.1016/j.bmc.2006.10.046
Vesicular stomatitis virus Vesicular stomatitis virus MIC 250000.0 nM 10.1021/jm070324z
Vesicular stomatitis virus Vesicular stomatitis virus MIC 300000.0 nM 10.1021/np060435l
Vesicular stomatitis virus Vesicular stomatitis virus MIC 500000.0 nM 10.1016/j.bmc.2006.10.046
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 4.0 ug.mL-1 10.1021/jm00386a007
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 16.0 ug.mL-1 10.1021/jm050772b
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 20.0 ug.mL-1 10.1021/jm950891z
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 30.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 70.0 ug.mL-1 10.1021/jm00220a027
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 150.0 ug.mL-1 10.1016/j.ejmech.2009.02.030
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 240.0 ug.mL-1 10.1021/jm050772b
Vesicular stomatitis virus Vesicular stomatitis virus MIC50 300.0 ug.mL-1 10.1021/jm00386a007
Vesicular stomatitis virus Vesicular stomatitis virus Selectivity index 27.26 None 10.1016/s0960-894x(02)00182-8
Vesicular stomatitis virus Vesicular stomatitis virus Tox50 400.0 ug ml-1 10.1021/jm00383a027
Vesicular stomatitis virus Vesicular stomatitis virus Virus rating 0.8 None 10.1021/jm00377a002
Visna-maedi virus Visna-maedi virus Activity nan None 10.1021/jm00126a027
West Nile virus West Nile virus EC50 18000.0 nM 10.1021/jm051229y
West Nile virus West Nile virus EC50 30000.0 nM 10.1021/jm051229y
West Nile virus West Nile virus EC50 46000.0 nM 10.1021/acs.jmedchem.8b01403
West Nile virus West Nile virus EC50 71200.0 nM 10.1021/acs.jmedchem.8b01403
West Nile virus West Nile virus EC50 90000.0 nM 10.1021/acs.jmedchem.8b01403
West Nile virus West Nile virus EC50 95000.0 nM 10.1021/acs.jmedchem.8b01403
West Nile virus West Nile virus EC50 nan None 10.1016/j.bmc.2015.09.035
West Nile virus West Nile virus IC50 6700.0 nM 10.1016/j.ejmech.2021.113683
West Nile virus West Nile virus IC50 9500.0 nM 10.1016/j.ejmech.2021.113683
West Nile virus West Nile virus IC50 91500.0 nM 10.1021/acs.jmedchem.0c01039
West Nile virus West Nile virus IC50 nan None 10.1016/j.ejmech.2021.113683
West Nile virus West Nile virus Inhibition 90.0 % 10.1021/acsmedchemlett.1c00515
Yellow fever virus Yellow fever virus Activity 1.3 g 10.1128/aac.01494-06
Yellow fever virus Yellow fever virus Activity 1.3 IU/L 10.1128/aac.01494-06
Yellow fever virus Yellow fever virus Activity 6.0 day 10.1128/aac.01494-06
Yellow fever virus Yellow fever virus Activity 103.0 IU/L 10.1128/aac.01074-08
Yellow fever virus Yellow fever virus Activity 120.0 IU/L 10.1128/aac.01494-06
Yellow fever virus Yellow fever virus Activity nan None 10.1021/np50055a001
Yellow fever virus Yellow fever virus Activity nan None 10.1128/aac.01074-08
Yellow fever virus Yellow fever virus EC50 28000.0 nM 10.1128/aac.01074-08
Yellow fever virus Yellow fever virus EC50 100000.0 nM 10.1016/j.bmc.2009.05.020
Yellow fever virus Yellow fever virus EC50 100000.0 nM 10.1016/j.bmc.2010.02.037
Yellow fever virus Yellow fever virus EC50 100000.0 nM 10.1016/j.bmc.2014.06.043
Yellow fever virus Yellow fever virus EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
Yellow fever virus Yellow fever virus EC50 250000.0 nM 10.1016/j.bmc.2018.05.034
Yellow fever virus Yellow fever virus EC50 250000.0 nM 10.1016/j.ejmech.2017.04.070
Yellow fever virus Yellow fever virus EC50 250000.0 nM 10.1039/d3md00055a
Yellow fever virus Yellow fever virus EC50 nan None 10.1128/aac.01074-08
Yellow fever virus Yellow fever virus EC90 690.0 uM 10.1128/aac.01074-08
Yellow fever virus Yellow fever virus TIME 504.0 hr 10.1128/aac.01074-08
Zika virus NS5 EC50 20800.0 nM 10.1021/acs.jmedchem.9b00775
Zika virus Zika virus Activity 80.0 % 10.1016/j.bmc.2022.116858
Zika virus Zika virus Activity nan None 10.1016/j.bmcl.2019.126881
Zika virus Zika virus EC 20.0 ug ml-1 10.1021/acs.jnatprod.2c00464
Zika virus Zika virus EC 40.0 ug ml-1 10.1021/acs.jnatprod.2c00464
Zika virus Zika virus EC50 3950.0 nM 10.1016/j.bmcl.2019.126881
Zika virus Zika virus EC50 12000.0 nM 10.1021/acsmedchemlett.8b00583
Zika virus Zika virus EC50 14100.0 nM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC50 17700.0 nM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC50 33000.0 nM 10.1016/j.bmcl.2019.126906
Zika virus Zika virus EC50 33000.0 nM 10.1021/acs.jmedchem.0c00232
Zika virus Zika virus EC50 36100.0 nM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC50 38100.0 nM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC50 80000.0 nM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC50 83000.0 nM 10.1021/acs.jnatprod.2c00464
Zika virus Zika virus EC50 101000.0 nM 10.1021/acs.jnatprod.2c00464
Zika virus Zika virus EC50 250000.0 nM 10.1039/d3md00055a
Zika virus Zika virus EC50 nan None 10.1021/acsmedchemlett.8b00583
Zika virus Zika virus EC90 47.4 uM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC90 51.0 uM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC90 70.3 uM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC90 75.9 uM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus EC90 80.0 uM 10.1016/j.ejmech.2022.114275
Zika virus Zika virus IC50 2200.0 nM 10.1016/j.ejmech.2021.113683
Zika virus Zika virus IC50 3800.0 nM 10.1016/j.ejmech.2021.113683
Zika virus Zika virus IC50 4400.0 nM 10.1016/j.ejmech.2021.113683
Zika virus Zika virus IC50 6900.0 nM 10.1016/j.bmc.2022.116858
Zika virus Zika virus IC50 29900.0 nM 10.1016/j.bmc.2022.116858
Zika virus Zika virus Inhibition 37.0 % 10.1016/j.bmcl.2019.126906
Zika virus Zika virus Inhibition 50.0 % 10.1021/acs.jnatprod.2c00464
Zika virus Zika virus Inhibition 55.0 % 10.1021/acs.jnatprod.2c00464
Zika virus Zika virus Inhibition 80.0 % 10.1021/acsmedchemlett.1c00515
Zika virus Zika virus Inhibition 93.0 % 10.1021/acs.jnatprod.1c00199
Zika virus Zika virus Survival 82.0 % 10.1021/acsmedchemlett.9b00405
None ADMET Activity 12.0 % 10.1016/j.bmcl.2007.01.085
None ADMET Activity 26.78 % 10.1016/j.ejmech.2014.03.074
None ADMET Activity 32.6 % 10.1021/jm401330r
None ADMET Activity 71.37 % 10.1016/j.ejmech.2014.03.074
None ADMET Activity 80.0 % 10.1021/acs.jmedchem.5b01047
None ADMET Activity nan None 10.1016/j.ejmech.2021.113684
None ADMET AUC Ratio 1.015 None 10.1038/s41586-020-2286-9
None ADMET CC50 62.5 ug.mL-1 10.1021/np050498o
None ADMET CC50 300.0 nM 10.1016/j.bmcl.2016.05.072
None ADMET CC50 500.0 ug.mL-1 10.1016/j.bmcl.2013.07.023
None ADMET CC50 5000.0 nM 10.1016/j.ejmech.2016.03.080
None ADMET CC50 20000.0 nM 10.1016/j.bmcl.2014.03.012
None ADMET CC50 30000.0 nM 10.1016/j.bmcl.2015.09.029
None ADMET CC50 30500.0 nM 10.1016/j.bmcl.2015.09.029
None ADMET CC50 54000.0 nM 10.1016/j.ejmech.2007.10.023
None ADMET CC50 56000.0 nM 10.1021/np5002829
None ADMET CC50 56310.0 nM 10.1016/j.ejmech.2014.03.074
None ADMET CC50 57000.0 nM 10.1016/j.bmcl.2015.04.006
None ADMET CC50 66000.0 nM 10.1128/aac.00078-08
None ADMET CC50 71000.0 nM 10.1021/jm058200e
None ADMET CC50 77000.0 nM 10.1128/aac.00078-08
None ADMET CC50 86000.0 nM 10.1021/jm800927r
None ADMET CC50 95000.0 nM 10.1128/aac.00078-08
None ADMET CC50 100000.0 nM 10.1016/j.bmc.2009.05.020
None ADMET CC50 100000.0 nM 10.1016/j.bmc.2010.02.037
None ADMET CC50 100000.0 nM 10.1016/j.bmc.2014.06.043
None ADMET CC50 100000.0 nM 10.1016/j.bmc.2014.08.024
None ADMET CC50 100000.0 nM 10.1016/j.bmc.2015.09.035
None ADMET CC50 100000.0 nM 10.1016/j.bmcl.2013.07.005
None ADMET CC50 100000.0 nM 10.1016/j.bmcl.2015.04.006
None ADMET CC50 100000.0 nM 10.1021/acs.jmedchem.5b01064
None ADMET CC50 100000.0 nM 10.1021/jm049677d
None ADMET CC50 100000.0 nM 10.1021/jm800927r
None ADMET CC50 177940.0 nM 10.1016/j.bmc.2010.05.066
None ADMET CC50 200000.0 nM 10.1016/j.bmc.2007.08.025
None ADMET CC50 229000.0 nM 10.1021/jm800927r
None ADMET CC50 250000.0 nM 10.1021/acs.jmedchem.5b01935
None ADMET CC50 409000.0 nM 10.1021/acs.jmedchem.5b00108
None ADMET CC50 410000.0 nM 10.1016/j.bmcl.2015.02.059
None ADMET CC50 1000000.0 nM 10.1016/j.bmc.2015.07.039
None ADMET CC50 1060000.0 nM 10.1021/jm901741p
None ADMET CC50 nan None 10.1016/j.bmc.2010.08.048
None ADMET CC50 nan None 10.1016/j.ejmech.2013.07.053
None ADMET CC50 nan None 10.1128/aac.00211-07
None ADMET CC50/EC50 67.0 None 10.1021/jm049677d
None ADMET CC50/EC50 150.0 None 10.1021/jm049677d
None ADMET CL 5.2 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET EC50 48.0 ug.mL-1 10.1021/jm025569k
None ADMET EC50 80.0 ug.mL-1 10.1021/jm025569k
None ADMET EC50 240.0 ug.mL-1 10.1021/jm025569k
None ADMET EC50 670.0 nM 10.1021/jm049677d
None ADMET EC50 1500.0 nM 10.1021/jm049677d
None ADMET EC50rel 1.0 uM 10.1021/jm049677d
None ADMET IC50 25.0 ug.mL-1 10.1021/np9703914
None ADMET IC50 35.0 ug.mL-1 10.1021/np9703914
None ADMET LC50 62.5 ug.mL-1 10.1021/np010174+
None ADMET MCC 7.0 ug.mL-1 10.1021/jm00152a007
None ADMET MCC 100.0 ug.mL-1 10.1021/jm00152a007
None ADMET MCC 100.0 ug.mL-1 10.1021/jm00199a015
None ADMET MCC 400.0 ug.mL-1 10.1021/jm00095a019
None ADMET MCC 400.0 ug.mL-1 10.1021/jm00130a024
None ADMET MCC 400.0 ug.mL-1 10.1021/jm00152a007
None ADMET MCC 400.0 ug.mL-1 10.1021/jm00389a005
None ADMET MCC 100000.0 nM 10.1016/j.bmc.2010.02.015
None ADMET MIC 20.0 ug.mL-1 10.1021/jm00095a019
None ADMET MIC 200.0 ug.mL-1 10.1021/jm00095a019
None ADMET MIC 300.0 ug.mL-1 10.1021/jm00035a010
None ADMET MIC 400.0 ug.mL-1 10.1021/jm00035a010
None ADMET MIC 400.0 ug.mL-1 10.1021/jm00095a019
None ADMET MIC 400.0 ug.mL-1 10.1021/jm00125a024
None ADMET MNCC nan None 10.1021/np050498o
None ADMET MRT 45.0 hr 10.1124/dmd.108.020479
None ADMET Permeability coefficient 4.1 None 10.1021/jm960163r
None ADMET Ratio 30.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 49.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 59.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 60.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 65.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 78.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 101.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio 113.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio CC50/EC50 2.3 None 10.1016/j.bmc.2011.10.058
None ADMET Ratio CC50/EC50 3.99 None 10.1016/j.ejmech.2019.111861
None ADMET Ratio CC50/EC50 17.3 None 10.1016/j.ejmech.2019.111861
None ADMET Ratio CC50/EC50 18.0 None 10.1021/acs.jnatprod.2c00766
None ADMET Ratio CC50/EC50 60.2 None 10.1021/jm901741p
None ADMET Ratio CC50/EC50 71.0 None 10.1021/acs.jnatprod.2c00766
None ADMET Ratio CC50/EC50 77.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 83.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 91.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 98.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 130.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 150.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 670.0 None 10.1016/j.bmcl.2023.129219
None ADMET Ratio CC50/EC50 nan None 10.1128/aac.00211-07
None ADMET Ratio CC50/IC50 3.67 None 10.1016/j.bmcl.2022.128681
None ADMET Ratio CC50/IC50 20.8 None 10.1021/np050498o
None ADMET Ratio CC50/IC50 21.0 None 10.1021/np800792d
None ADMET Ratio CC50/IC50 24.0 None 10.1021/np030470h
None ADMET Ratio CC50/IC50 41.6 None 10.1016/j.bmc.2022.116858
None ADMET Ratio CC50/IC50 46.8 None 10.1016/j.bmc.2022.116858
None ADMET Ratio CC50/IC50 54.0 None 10.1021/acs.jnatprod.2c00322
None ADMET Ratio CC50/IC50 175.4 None 10.1016/j.ejmech.2021.113208
None ADMET Ratio CC50/IC50 239.7 None 10.1016/j.bmc.2022.116858
None ADMET Ratio IC50 3.65 None 10.1016/j.ejmech.2020.112862
None ADMET Ratio IC50/EC50 19.0 None 10.1021/np9703914
None ADMET Ratio IC50/EC50 37.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 40.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 48.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 52.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 55.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 56.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 65.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 67.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 68.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 80.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 94.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 117.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 128.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 139.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 156.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Ratio IC50/EC50 305.0 None 10.1016/j.bmcl.2010.02.074
None ADMET Selectivity Index 1.3 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 21.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 21.6 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 22.57 None 10.1016/j.ejmech.2021.113684
None ADMET Selectivity Index 26.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 30.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 45.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 46.0 None 10.1016/j.ejmech.2021.113591
None ADMET Selectivity Index 49.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 50.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 53.0 None 10.1016/j.ejmech.2021.113683
None ADMET Selectivity Index 74.3 None 10.1016/j.ejmech.2021.113738
None ADMET Selectivity Index 91.0 None 10.1016/j.ejmech.2021.113683
None ADMET T1/2 45.0 hr 10.1124/dmd.108.020479
None ADMET TC50 256.1 uM 10.1021/np800542t
None ADMET TC50 3000.0 uM 10.1021/np500252q
None ADMET TC50 3000.0 uM 10.1021/np500650t
None ADMET Therapeutic index 1.1 None 10.1021/jm00117a004
None ADMET Therapeutic index 1.5 None 10.1021/jm00147a013
None ADMET Therapeutic index 4.0 None 10.1021/jm00147a013
None ADMET Therapeutic index 5.0 None 10.1021/jm00117a004
None ADMET TI 6.0 None 10.1021/np800542t
None ADMET TI 23.9 None 10.1021/np800542t
None ADMET TI 24.0 None 10.1021/np010174+
None ADMET TI 28.3 None 10.1016/j.bmcl.2019.126770
None ADMET TI 37.37 None 10.1016/j.bmcl.2015.12.100
None ADMET TI 147.0 None 10.1021/np500252q
None ADMET TI 150.0 None 10.1021/np500650t
None ADMET TI 770.7 None 10.1016/j.ejmech.2020.112577
None ADMET Toxic level nan None 10.1021/jm00148a015
None ADMET Toxic level nan None 10.1021/jm00377a002
None ADMET Vdss 14.0 L.kg-1 10.1124/dmd.108.020479
None Epithelial cell EC50 1024600.0 nM 10.1016/s0960-894x(03)00231-2
None ESM IC50 45.0 ug.mL-1 10.1021/jm00075a030
None ESM IC50 110.0 ug.mL-1 10.1021/jm00075a030
None ESM IC50 135.0 ug.mL-1 10.1021/jm00075a030
None ESM IC50 300.0 ug.mL-1 10.1021/jm00075a030
None ESM IC50 350.0 ug.mL-1 10.1021/jm00075a030
None ESM IC50 400.0 ug.mL-1 10.1021/jm00075a030
None ESM MIC 400.0 ug.mL-1 10.1021/jm00035a010
None HEF MIC50 20.0 ug.mL-1 10.1021/jm00044a010
None HEF MIC50 70.0 ug.mL-1 10.1021/jm00044a010
None HEF MIC50 200.0 ug.mL-1 10.1021/jm00044a010
None HEF MIC50 400.0 ug.mL-1 10.1021/jm00044a010
None HEF MIC50 400.0 ug.mL-1 10.1021/jm950891z
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx1000865
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity Hepatotoxicity nan None 10.1124/dmd.110.035113
None Hepatotoxicity HepSE_bilirubinemia 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 4.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity LTKB_BD DILI severity score 7.0 None 10.1016/j.drudis.2011.05.007
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 0.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Laryngeal epithelioma cell line Virus rating 1.1 None 10.1021/jm00140a006
None Laryngeal epithelioma cell line Virus rating 1.2 None 10.1021/jm00140a006
None Laryngeal epithelioma cell line Virus rating 1.4 None 10.1021/jm00140a006
None Laryngeal epithelioma cell line Virus rating 1.6 None 10.1021/jm00140a006
None Molecular identity unknown Potency 42163.2 nM None
None NON-PROTEIN TARGET Activity 9.3 10'6PFU/ml 10.1021/jm401330r
None NON-PROTEIN TARGET Activity 53.5 10'6PFU/ml 10.1021/jm401330r
None NON-PROTEIN TARGET Activity 127.0 % 10.1021/jm00205a025
None NON-PROTEIN TARGET CC50 100000.0 nM 10.1016/j.bmc.2014.06.043
None NON-PROTEIN TARGET EC50 16.0 ug.mL-1 10.1016/j.ejmech.2015.08.005
None NON-PROTEIN TARGET EC50 24.0 ug.mL-1 10.1016/j.ejmech.2015.08.005
None NON-PROTEIN TARGET EC50 83.3 ug.mL-1 10.1021/jm400460d
None NON-PROTEIN TARGET EC50 1300.0 nM 10.1016/j.ejmech.2016.03.080
None NON-PROTEIN TARGET EC50 1300.0 nM 10.1016/j.ejmech.2016.04.077
None NON-PROTEIN TARGET EC50 4600.0 nM 10.1016/j.bmc.2012.07.028
None NON-PROTEIN TARGET EC50 6800.0 nM 10.1016/j.bmcl.2014.06.018
None NON-PROTEIN TARGET EC50 7300.0 nM 10.1016/j.bmcl.2014.06.018
None NON-PROTEIN TARGET EC50 12000.0 nM 10.1016/j.ejmech.2015.02.028
None NON-PROTEIN TARGET EC50 13100.0 nM 10.1021/acs.jmedchem.5b01047
None NON-PROTEIN TARGET EC50 18400.0 nM 10.1021/acs.jmedchem.5b01047
None NON-PROTEIN TARGET EC50 20000.0 nM 10.1021/acs.jmedchem.5b01047
None NON-PROTEIN TARGET EC50 50000.0 nM 10.1016/j.bmcl.2016.12.010
None NON-PROTEIN TARGET EC50 100000.0 nM 10.1016/j.bmc.2015.09.035
None NON-PROTEIN TARGET EC50 112000.0 nM 10.1016/j.bmcl.2016.12.010
None NON-PROTEIN TARGET EC50 250000.0 nM 10.1016/j.bmcl.2016.12.010
None NON-PROTEIN TARGET EC50 250000.0 nM 10.1016/j.ejmech.2015.08.008
None NON-PROTEIN TARGET EC50 250000.0 nM 10.1039/c1md00094b
None NON-PROTEIN TARGET Fu 1.0 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET GI 50.0 % 10.1016/j.ejmech.2013.08.053
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 3.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 33.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 16000.0 nM 10.1021/jm401330r
None NON-PROTEIN TARGET IC50 253100.0 nM 10.1021/np500124e
None NON-PROTEIN TARGET Inhibition 10.0 % 10.1021/acs.jmedchem.5b01047
None NON-PROTEIN TARGET Inhibition nan % 10.1021/acs.jmedchem.5b01047
None NON-PROTEIN TARGET MCC 400.0 ug.mL-1 10.1021/jm00090a007
None NON-PROTEIN TARGET MCC 400.0 ug.mL-1 10.1021/jm960500w
None NON-PROTEIN TARGET MCC 250000.0 nM 10.1016/j.bmcl.2016.12.010
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1021/jm00045a025
None NON-PROTEIN TARGET MIC 40.0 ug.mL-1 10.1021/jm00090a007
None NON-PROTEIN TARGET MIC 46.0 ug.mL-1 10.1021/jm00045a025
None NON-PROTEIN TARGET MIC 70.0 ug.mL-1 10.1021/jm00090a007
None NON-PROTEIN TARGET MIC 103.0 ug.mL-1 10.1021/jm00045a025
None NON-PROTEIN TARGET MIC 120.0 ug.mL-1 10.1021/jm00045a025
None NON-PROTEIN TARGET MIC 150.0 ug.mL-1 10.1021/jm00090a007
None NON-PROTEIN TARGET MIC 250.0 ug.mL-1 10.1021/jm00045a025
None NON-PROTEIN TARGET MIC 300.0 ug.mL-1 10.1021/jm00090a007
None NON-PROTEIN TARGET MIC 400.0 ug.mL-1 10.1021/jm00090a007
None NON-PROTEIN TARGET MIC50 5.6 ug.mL-1 10.1021/jm950891z
None NON-PROTEIN TARGET MIC50 48.7 ug.mL-1 10.1021/jm950891z
None NON-PROTEIN TARGET Potency 2818.4 nM None
None NON-PROTEIN TARGET Potency 8912.5 nM None
None NON-PROTEIN TARGET Potency 14125.4 nM None
None NON-PROTEIN TARGET Potency 15848.9 nM None
None NON-PROTEIN TARGET Ratio CC50/EC50 3.7 None 10.1016/j.bmc.2007.08.025
None NON-PROTEIN TARGET Ratio CC50/EC50 32.0 None 10.1016/j.ejmech.2013.12.055
None NON-PROTEIN TARGET Ratio CC50/EC50 76.0 None 10.1016/j.ejmech.2013.12.055
None NON-PROTEIN TARGET Ratio CC50/EC50 130.0 None 10.1016/j.ejmech.2013.12.055
None NON-PROTEIN TARGET Ratio CC50/EC50 160.0 None 10.1016/j.ejmech.2013.12.055
None NON-PROTEIN TARGET Selectivity index 5.7 None 10.1021/jm00127a007
None NON-PROTEIN TARGET Virus rating 2.8 None 10.1021/jm00388a036
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Unchecked Ac50 0.5012 uM None
None Unchecked Ac50 0.631 uM None
None Unchecked Ac50 2.239 uM None
None Unchecked Ac50 3.162 uM None
None Unchecked Ac50 17.78 uM None
None Unchecked AC50 510.0 nM None
None Unchecked AC50 631.0 nM None
None Unchecked AC50 2238.7 nM None
None Unchecked AC50 3162.3 nM None
None Unchecked AC50 17782.8 nM None
None Unchecked Activity 3.13 10^10/M 10.1016/j.bmc.2007.08.029
None Unchecked Activity 26.78 % 10.1016/j.ejmech.2017.12.006
None Unchecked Activity 62.7 % 10.1016/j.ejmech.2021.113684
None Unchecked Activity 71.37 % 10.1016/j.ejmech.2017.12.006
None Unchecked Activity 74.0 % 10.1021/jm00397a010
None Unchecked Activity 155.0 % 10.1021/jm00397a010
None Unchecked Activity nan None 10.1016/j.bmc.2007.08.029
None Unchecked Activity nan None 10.1016/j.ejmech.2019.112009
None Unchecked Activity nan None 10.1016/j.ejmech.2022.114275
None Unchecked Activity nan None 10.1021/acsmedchemlett.2c00196
None Unchecked Activity nan None 10.1021/jm00192a009
None Unchecked Activity nan None 10.1128/aac.00010-10
None Unchecked CC50 75.0 ug.mL-1 10.1016/j.bmcl.2017.11.029
None Unchecked CC50 16300.0 nM 10.1016/j.ejmech.2019.112031
None Unchecked CC50 48980.0 nM 10.1016/j.bmc.2019.04.015
None Unchecked CC50 54400.0 nM 10.1016/j.bmc.2017.05.056
None Unchecked CC50 62000.0 nM 10.1016/j.ejmech.2017.09.060
None Unchecked CC50 100000.0 nM 10.1016/j.bmc.2020.115679
None Unchecked CC50 106270.0 nM 10.1016/j.ejmech.2017.12.006
None Unchecked CC50 200000.0 nM 10.1016/j.ejmech.2020.112147
None Unchecked CC50 409000.0 nM 10.1021/acsmedchemlett.8b00583
None Unchecked CC50 1019700.0 nM 10.1016/j.bmc.2022.116858
None Unchecked CC50 nan None 10.1016/j.bmc.2015.12.008
None Unchecked Control 124.0 % 10.1021/jm9905514
None Unchecked Control 131.0 % 10.1021/jm9905514
None Unchecked Control 143.0 % 10.1021/jm9905514
None Unchecked EC50 240.0 ug.mL-1 10.1021/jm025569k
None Unchecked EC50 3900.0 nM 10.1016/j.ejmech.2017.04.070
None Unchecked EC50 7700.0 nM 10.1016/j.bmc.2017.05.056
None Unchecked EC50 8400.0 nM 10.1016/j.ejmech.2017.04.070
None Unchecked EC50 9800.0 nM 10.1021/acs.jmedchem.7b00908
None Unchecked EC50 12000.0 nM 10.1021/acs.jmedchem.7b00908
None Unchecked EC50 15000.0 nM 10.1021/jm401560v
None Unchecked EC50 16300.0 nM 10.1016/j.bmc.2020.115679
None Unchecked EC50 17950.0 nM 10.1016/j.bmcl.2017.03.015
None Unchecked EC50 18000.0 nM 10.1021/acs.jmedchem.5b00012
None Unchecked EC50 19000.0 nM 10.1016/j.ejmech.2017.04.070
None Unchecked EC50 20500.0 nM 10.1016/j.ejmech.2019.111861
None Unchecked EC50 23800.0 nM 10.1021/acs.jmedchem.5b01935
None Unchecked EC50 24900.0 nM 10.1021/jm500300r
None Unchecked EC50 43000.0 nM 10.1016/j.ejmech.2020.112198
None Unchecked EC50 100000.0 nM 10.1016/j.ejmech.2019.112031
None Unchecked EC50 100000.0 nM 10.1021/acsmedchemlett.2c00196
None Unchecked EC50 250000.0 nM 10.1039/d3md00055a
None Unchecked Fluorescence intensity 226933.0 None 10.1016/j.bmc.2007.08.029
None Unchecked Hepatotoxicity (acute) 2.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 1.6 ug.mL-1 10.1021/jm900652e
None Unchecked IC50 41.45 ug.mL-1 10.1016/j.bmc.2020.115757
None Unchecked IC50 1000.0 nM 10.1016/j.bmc.2012.01.054
None Unchecked IC50 5000.0 nM 10.1021/acsmedchemlett.2c00196
None Unchecked IC50 22000.0 nM 10.1016/j.bmc.2012.01.054
None Unchecked IC50 44000.0 nM 10.1016/j.bmcl.2020.127653
None Unchecked IC50 379100.0 nM 10.1016/j.ejmech.2016.09.097
None Unchecked IC50 379120.0 nM 10.1016/j.bmcl.2017.01.022
None Unchecked IC50 500000.0 nM 10.1016/j.ejmech.2016.09.097
None Unchecked IC50 2088000.0 nM 10.1016/j.bmcl.2017.01.022
None Unchecked IC50 2088000.0 nM 10.1016/j.ejmech.2016.09.097
None Unchecked IC50 40948000.0 nM 10.1016/j.bmcl.2017.01.022
None Unchecked IC50 nan None 10.1021/jm500300r
None Unchecked IC50 nan None None
None Unchecked ID50 20.0 ug ml-1 10.1021/jm00220a027
None Unchecked ID50 42.0 uM 10.1021/jm00163a054
None Unchecked Inhibition -80.0 % 10.1128/aac.00790-06
None Unchecked Inhibition 85.47 % 10.1016/j.bmcl.2017.03.015
None Unchecked Inhibition 90.0 % 10.1128/aac.00790-06
None Unchecked Inhibition 99.07 % 10.1016/j.ejmech.2021.113739
None Unchecked Inhibition 99.9 % 10.1128/aac.00790-06
None Unchecked Inhibition nan % 10.1016/j.bmc.2012.01.054
None Unchecked Inhibition nan % 10.1038/nchembio873
None Unchecked Inhibition nan % 10.1039/C2MD20286G
None Unchecked Kcat/Km 8.4 10^-6 microM/s 10.1021/jm7009952
None Unchecked Ki nan None None
None Unchecked Kinact 7.6 10^-4/s 10.1016/j.bmc.2007.08.029
None Unchecked Kinact 194.0 uM 10.1016/j.bmc.2007.08.029
None Unchecked KR 586.0 uM 10.1016/j.bmc.2007.08.029
None Unchecked MCC 250000.0 nM 10.1016/j.ejmech.2019.111739
None Unchecked Potency 1000.0 nM None
None Unchecked Potency 7079.5 nM None
None Unchecked Potency 11220.2 nM None
None Unchecked Potency 20587.8 nM None
None Unchecked Potency 32642.7 nM None
None Unchecked Potency 35481.3 nM None
None Unchecked Ratio 0.19 None 10.1021/jm00389a019
None Unchecked Ratio 0.45 None 10.1021/jm00389a019
None Unchecked Ratio 1.0 None 10.1016/j.bmc.2015.12.008
None Unchecked Ratio 2.0 None 10.1016/j.bmc.2009.01.009
None Unchecked Ratio 2.0 None 10.1016/j.bmcl.2007.04.108
None Unchecked Ratio 2.9 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 3.0 None 10.1021/jm00397a010
None Unchecked Ratio 3.92 /M/s 10.1016/j.bmc.2007.08.029
None Unchecked Ratio 4.0 None 10.1016/j.bmc.2015.12.008
None Unchecked Ratio 5.0 None 10.1016/j.bmc.2015.12.008
None Unchecked Ratio 8.5 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 11.0 None 10.1016/j.bmc.2015.12.008
None Unchecked Ratio 11.8 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 12.0 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 12.7 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 16.4 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 17.0 None 10.1016/j.bmc.2015.12.008
None Unchecked Ratio 18.2 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 45.5 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio 47.6 None 10.1016/S0960-894X(97)10154-8
None Unchecked Ratio CC50/EC50 0.91 None 10.1016/j.bmcl.2015.09.029
None Unchecked Ratio CC50/EC50 1.0 None 10.1016/j.bmcl.2015.09.029
None Unchecked Ratio CC50/EC50 1.1 None 10.1128/aac.00078-08
None Unchecked Ratio CC50/EC50 1.4 None 10.1128/aac.00078-08
None Unchecked Ratio CC50/EC50 1.5 None 10.1016/j.bmc.2010.05.066
None Unchecked Ratio CC50/EC50 1.8 None 10.1128/aac.00078-08
None Unchecked Ratio CC50/EC50 2.0 None 10.1016/j.ejmech.2015.08.005
None Unchecked Ratio CC50/EC50 2.8 None 10.1016/j.bmcl.2015.04.006
None Unchecked Ratio CC50/EC50 3.0 None 10.1016/j.bmcl.2015.04.006
None Unchecked Ratio CC50/EC50 3.0 None 10.1016/j.bmcl.2019.02.027
None Unchecked Ratio CC50/EC50 3.0 None 10.1016/j.bmcl.2019.126906
None Unchecked Ratio CC50/EC50 3.0 None 10.1016/j.ejmech.2017.09.060
None Unchecked Ratio CC50/EC50 3.6 None 10.1021/jm300612z
None Unchecked Ratio CC50/EC50 3.65 None 10.1021/acs.jmedchem.0c00626
None Unchecked Ratio CC50/EC50 3.8 None 10.1016/j.ejmech.2016.03.080
None Unchecked Ratio CC50/EC50 4.47 None 10.1021/np5002829
None Unchecked Ratio CC50/EC50 6.0 None 10.1021/acs.jmedchem.0c00232
None Unchecked Ratio CC50/EC50 6.1 None 10.1016/j.ejmech.2019.112031
None Unchecked Ratio CC50/EC50 6.1 None 10.1021/acs.jmedchem.5b01064
None Unchecked Ratio CC50/EC50 7.1 None 10.1016/j.bmc.2017.05.056
None Unchecked Ratio CC50/EC50 10.0 None 10.1016/j.bmcl.2013.07.023
None Unchecked Ratio CC50/EC50 10.0 None 10.1016/j.bmcl.2014.01.024
None Unchecked Ratio CC50/EC50 10.0 None 10.1021/acs.jmedchem.5b00108
None Unchecked Ratio CC50/EC50 10.34 None 10.1021/acs.jnatprod.8b00735
None Unchecked Ratio CC50/EC50 11.42 None 10.1016/j.bmcl.2017.03.015
None Unchecked Ratio CC50/EC50 11.64 None 10.1016/j.ejmech.2007.10.023
None Unchecked Ratio CC50/EC50 12.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 12.5 None 10.1016/j.bmc.2015.09.035
None Unchecked Ratio CC50/EC50 13.3 None 10.1016/j.ejmech.2017.08.057
None Unchecked Ratio CC50/EC50 14.28 None 10.1016/j.bmc.2014.06.043
None Unchecked Ratio CC50/EC50 14.3 None 10.1016/j.bmc.2015.09.035
None Unchecked Ratio CC50/EC50 14.4 None 10.1021/jm701239a
None Unchecked Ratio CC50/EC50 15.0 None 10.1016/j.bmcl.2013.07.023
None Unchecked Ratio CC50/EC50 15.0 None 10.1016/j.ejmech.2013.05.044
None Unchecked Ratio CC50/EC50 15.0 None 10.1016/j.ejmech.2017.08.057
None Unchecked Ratio CC50/EC50 15.9 None 10.1016/j.bmcl.2018.12.063
None Unchecked Ratio CC50/EC50 18.0 None 10.1016/j.bmc.2014.08.024
None Unchecked Ratio CC50/EC50 19.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 19.5 None 10.1021/acs.jmedchem.5b01935
None Unchecked Ratio CC50/EC50 20.0 None 10.1016/j.bmcl.2013.07.023
None Unchecked Ratio CC50/EC50 20.0 None 10.1016/j.ejmech.2013.05.044
None Unchecked Ratio CC50/EC50 21.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 21.6 None 10.1016/j.bmcl.2018.12.063
None Unchecked Ratio CC50/EC50 25.0 None 10.1021/acsmedchemlett.9b00681
None Unchecked Ratio CC50/EC50 28.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 32.0 None 10.1016/j.ejmech.2015.08.005
None Unchecked Ratio CC50/EC50 33.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 34.0 None 10.1021/acsmedchemlett.8b00583
None Unchecked Ratio CC50/EC50 44.0 None 10.1016/j.bmcl.2019.02.027
None Unchecked Ratio CC50/EC50 51.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 69.0 None 10.1016/j.ejmech.2013.05.044
None Unchecked Ratio CC50/EC50 70.0 None 10.1128/aac.00356-07
None Unchecked Ratio CC50/EC50 75.2 None 10.1016/j.bmcl.2019.126881
None Unchecked Ratio CC50/EC50 81.0 None 10.1039/C6MD00657D
None Unchecked Ratio CC50/EC50 122.0 None 10.1016/j.bmcl.2019.126881
None Unchecked Ratio CC50/EC50 nan None 10.1021/acsmedchemlett.8b00583
None Unchecked Ratio CC50/IC50 2.0 None 10.1021/np030470h
None Unchecked Ratio CC50/IC50 2.7 None 10.1016/j.bmcl.2020.127518
None Unchecked Ratio CC50/IC50 4.0 None 10.1021/np500124e
None Unchecked Ratio CC50/IC50 4.47 None 10.1016/j.ejmech.2014.03.074
None Unchecked Ratio CC50/IC50 4.47 None 10.1016/j.ejmech.2017.10.001
None Unchecked Ratio CC50/IC50 5.2 None 10.1016/j.ejmech.2013.07.053
None Unchecked Ratio CC50/IC50 6.51 None 10.1016/j.ejmech.2020.112706
None Unchecked Ratio CC50/IC50 6.51 None 10.1016/j.ejmech.2021.113208
None Unchecked Ratio CC50/IC50 7.35 None 10.1016/j.bmc.2019.04.015
None Unchecked Ratio CC50/IC50 8.08 None 10.1016/j.ejmech.2017.12.006
None Unchecked Ratio CC50/IC50 9.0 None 10.1016/j.ejmech.2013.07.053
None Unchecked Ratio CC50/IC50 10.0 None 10.1016/j.bmcl.2007.02.026
None Unchecked Ratio CC50/IC50 19.98 None 10.1016/j.bmc.2008.06.049
None Unchecked Ratio CC50/IC50 20.8 None 10.1021/acs.jmedchem.0c00312
None Unchecked Ratio CC50/IC50 24.0 None 10.1021/np030470h
None Unchecked Ratio CC50/IC50 48.0 None 10.1016/j.bmcl.2018.04.057
None Unchecked Ratio CC50/IC50 48.0 None 10.1016/j.bmcl.2020.127653
None Unchecked Ratio CC50/IC50 61.0 None 10.1016/j.bmcl.2020.127677
None Unchecked Ratio CC50/IC50 71.0 None 10.1039/C8MD00442K
None Unchecked Ratio CC50/IC50 529.0 None 10.1016/j.bmc.2017.06.049
None Unchecked Ratio CC50/IC50 nan None 10.1016/j.ejmech.2013.07.053
None Unchecked Ratio CC50/IC50 nan None 10.1021/np050498o
None Unchecked Ratio IC50/EC50 10.8 None 10.1021/np9703914
None Unchecked Ratio IC50/EC50 11.0 None 10.1021/np9703914
None Unchecked Ratio IC50/EC50 59.0 None 10.1021/np960613i
None Unchecked Selectivity index 0.42 None 10.1016/j.bmcl.2007.01.085
None Unchecked Selectivity Index 0.14 None 10.1016/j.bmcl.2013.12.121
None Unchecked Selectivity Index 2.0 None 10.1016/j.bmc.2011.03.007
None Unchecked Selectivity Index 2.0 None 10.1016/j.ejmech.2010.08.009
None Unchecked Selectivity Index 3.65 None 10.1016/j.ejmech.2020.112559
None Unchecked Selectivity Index 3.9 None 10.1016/j.bmc.2011.03.007
None Unchecked Selectivity Index 3.9 None 10.1016/j.bmcl.2011.08.002
None Unchecked Selectivity Index 3.9 None 10.1021/ml500525s
None Unchecked Selectivity Index 4.0 None 10.1016/j.bmcl.2017.03.100
None Unchecked Selectivity Index 4.2 None 10.1021/ml500525s
None Unchecked Selectivity Index 4.3 None 10.1016/j.bmcl.2017.01.022
None Unchecked Selectivity Index 4.8 None 10.1021/ml500525s
None Unchecked Selectivity Index 4.9 None 10.1016/j.bmc.2011.03.007
None Unchecked Selectivity Index 5.2 None 10.1016/j.bmc.2018.12.014
None Unchecked Selectivity Index 6.0 None 10.1128/aac.01074-08
None Unchecked Selectivity Index 6.8 None 10.1021/acs.jnatprod.5b00325
None Unchecked Selectivity Index 6.8 None 10.1021/acs.jnatprod.6b00585
None Unchecked Selectivity Index 6.8 None 10.1021/np500951s
None Unchecked Selectivity Index 8.0 None 10.1016/j.bmcl.2017.03.100
None Unchecked Selectivity Index 9.0 None 10.1016/j.bmc.2011.03.007
None Unchecked Selectivity Index 9.0 None 10.1016/j.bmcl.2011.08.002
None Unchecked Selectivity Index 9.0 None 10.1016/j.bmcl.2015.02.059
None Unchecked Selectivity Index 9.0 None 10.1021/ml500525s
None Unchecked Selectivity Index 9.0 None 10.1021/np400638r
None Unchecked Selectivity Index 11.8 None 10.1016/j.ejmech.2016.09.097
None Unchecked Selectivity Index 11.8 None 10.1021/ml500525s
None Unchecked Selectivity Index 12.3 None 10.1016/j.bmcl.2017.01.022
None Unchecked Selectivity Index 16.76 None 10.1016/j.bmcl.2017.01.022
None Unchecked Selectivity Index 17.2 None 10.1016/j.bmcl.2017.01.022
None Unchecked Selectivity Index 18.0 None 10.1016/j.bmcl.2013.07.005
None Unchecked Selectivity Index 19.6 None 10.1016/j.bmcl.2017.01.022
None Unchecked Selectivity Index 21.6 None 10.1016/j.ejmech.2010.11.012
None Unchecked Selectivity Index 81.0 None 10.1016/j.bmcl.2012.09.084
None Unchecked Selectivity Index 81.0 None 10.1016/j.bmcl.2019.126745
None Unchecked Selectivity Index 86.9 None 10.1016/j.bmcl.2012.01.056
None Unchecked Selectivity Index 103.9 None 10.1016/j.ejmech.2012.07.008
None Unchecked Selectivity Index 135.0 None 10.1016/j.ejmech.2012.07.008
None Unchecked Selectivity Index 185.0 None 10.1016/j.ejmech.2014.02.029
None Unchecked Selectivity Index 205.6 None 10.1016/j.ejmech.2014.02.029
None Unchecked Selectivity Index 212.8 None 10.1016/j.ejmech.2014.02.029
None Unchecked Selectivity Index 329.4 None 10.1016/j.bmcl.2012.01.056
None Unchecked Selectivity Index 362.9 None 10.1016/j.bmcl.2019.08.009
None Unchecked Selectivity Index 476.3 None 10.1016/j.bmcl.2019.08.009
None Unchecked Selectivity Index 541.7 None 10.1016/j.ejmech.2012.07.008
None Unchecked Selectivity Index 560.0 None 10.1016/j.bmcl.2016.06.011
None Unchecked Selectivity Index 665.6 None 10.1016/j.bmcl.2012.01.056
None Unchecked Selectivity Index 714.0 None 10.1016/j.bmcl.2019.08.009
None Unchecked Selectivity Index 813.4 None 10.1021/acs.jnatprod.5b00325
None Unchecked Selectivity Index 819.8 None 10.1016/j.ejmech.2014.02.029
None Unchecked Selectivity Index 895.0 None 10.1021/acs.jnatprod.6b00585
None Unchecked Selectivity Index 1100.0 None 10.1016/j.bmcl.2016.06.011
None Unchecked Selectivity Index 1400.0 None 10.1016/j.bmcl.2016.06.011
None Unchecked Selectivity ratio 6.1 None 10.1016/j.bmc.2020.115679
None Unchecked SI 1.6 None 10.1021/jm00105a064
None Unchecked SI 6.3 None 10.1021/jm00105a064
None Unchecked SI 276.9 None 10.1016/s0960-894x(03)00231-2
None Unchecked TCID50 13.7 ug ml-1 10.1016/j.bmc.2020.115757

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT016268 N=C(N)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1>>NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1 enzymemap_79253
AKRT017302 NC(=O)c1nc[nH]n1.O=P(O)(O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1 enzymemap_38617
AKRT017303 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1>>NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)n1 enzymemap_44018