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Fagomine

AlkaPlorer ID: AK004772

Synonym: '', '3-epifagomine', '3-epi-fagomine', '(-)-3,4-di-epi-fagomine', 'Fagomine', '3,4-di-epi-fagomine', '3-epi-Fagomine'

IUPAC Name: None

Structure

SMILES: OC[C@H]1[NH2+]CC[C@H](O)[C@@H]1O

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InChI: InChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/p+1/t4-,5+,6-/m1/s1

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InChIKey: YZNNBIPIQWYLDM-NGJCXOISSA-O

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Santolina pectinata Santolina Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Bombyx mori Bombyx Bombycidae Lepidoptera Insecta Arthropoda Metazoa Eukaryota
Castanospermum australe Castanospermum Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Morus alba Morus Moraceae Rosales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Helichrysum drakensbergense Helichrysum Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Piper divaricatum Piper Piperaceae Piperales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Erythrina speciosa Erythrina Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Prunus prostrata Prunus Rosaceae Rosales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Prosopis africana Prosopis Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Richteria pyrethroides Richteria Asteraceae Asterales Magnoliopsida Streptophyta Viridiplantae Eukaryota
None Aglaonema Araceae Alismatales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Xanthocercis zambesiaca Xanthocercis Fabaceae Fabales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Commiphora sphaerocarpa Commiphora Burseraceae Sapindales Magnoliopsida Streptophyta Viridiplantae Eukaryota
Plakortis angulospiculatus Plakortis Plakinidae Homosclerophorida Homoscleromorpha Porifera Metazoa Eukaryota
Morus bombycis Morus Moraceae Rosales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 148.18200000000002

TPSA？: 77.30000000000001

MolLogP？: -2.9637999999999987

Number of H-Donors: 4

Number of H-Acceptors: 3

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bos taurus Alpha-glucosidase IC50 nan nM 10.1021/jm00048a006
Bos taurus Alpha-L-fucosidase 1 Inhibition 50.0 % 10.1016/j.bmc.2011.04.011
Bos taurus Beta-galactosidase IC50 1500.0 nM 10.1021/jm00048a006
Bos taurus Beta-galactosidase IC50 3000.0 nM 10.1016/j.bmc.2011.04.011
Bos taurus Beta-galactosidase IC50 3100.0 nM 10.1021/jm00048a006
Bos taurus Beta-galactosidase IC50 nan nM 10.1021/jm00048a006
Bos taurus Glucosylceramidase IC50 5600.0 nM 10.1016/j.bmc.2011.04.011
Caldicellulosiruptor saccharolyticus Beta-glucosidase A IC50 100000.0 nM 10.1021/jm00048a006
Caldicellulosiruptor saccharolyticus Beta-glucosidase A IC50 nan nM 10.1021/jm00048a006
Canavalia ensiformis Alpha-mannosidase Inhibition nan % 10.1016/j.ejmech.2015.08.038
Coffea arabica Alpha-galactosidase Inhibition nan % 10.1016/j.ejmech.2015.08.038
Escherichia coli K-12 Beta-galactosidase Inhibition nan % 10.1016/j.ejmech.2015.08.038
Homo sapiens Alpha-L-fucosidase I IC50 1000000.0 nM 10.1021/jm00048a006
Homo sapiens Beta-glucocerebrosidase Inhibition 50.0 % 10.1016/j.bmc.2011.04.011
Homo sapiens Beta-glucosidase IC50 1000000.0 nM 10.1021/ml200050s
Homo sapiens Neutral alpha-glucosidase AB IC50 nan nM 10.1021/jm00048a006
Mus musculus Ceramide glucosyltransferase IC50 10000.0 nM 10.1021/ml200050s
Mus musculus Ceramide glucosyltransferase Inhibition nan % 10.1021/ml200050s
Mus musculus Mus musculus Activity nan None 10.1021/np970277l
Mus musculus Neutral alpha-glucosidase C IC50 6400.0 nM 10.1021/jm00048a006
Rattus norvegicus Acidic alpha-glucosidase IC50 500000.0 nM 10.1021/jm00048a006
Rattus norvegicus Acidic alpha-glucosidase IC50 nan nM 10.1021/jm00048a006
Rattus norvegicus Beta-galactosidase IC50 4000.0 nM 10.1021/jm00048a006
Rattus norvegicus Beta-galactosidase IC50 nan nM 10.1021/jm00048a006
Rattus norvegicus Lactase-glycosylceramidase IC50 1900.0 nM 10.1021/jm00048a006
Rattus norvegicus Lactase-glycosylceramidase IC50 4300.0 nM 10.1016/j.bmc.2011.04.011
Rattus norvegicus Sucrase-isomaltase IC50 6000.0 nM 10.1021/np960646y
Rattus norvegicus Sucrase-isomaltase Inhibition 50.0 % 10.1016/j.bmc.2011.04.011
Rattus norvegicus Trehalase IC50 nan nM 10.1021/jm00048a006
None Unchecked IC50 3000.0 nM 10.1021/np960646y
None Unchecked IC50 4000.0 nM 10.1021/np960646y
None Unchecked IC50 39000.0 nM 10.1016/j.bmc.2011.04.011
None Unchecked IC50 100000.0 nM 10.1021/np960646y
None Unchecked IC50 120000.0 nM 10.1016/j.bmc.2011.04.011
None Unchecked IC50 120000.0 nM 10.1021/np960646y
None Unchecked IC50 700000.0 nM 10.1021/ml200050s
None Unchecked IC50 740000.0 nM 10.1021/np960646y
None Unchecked IC50 nan nM 10.1021/jm00048a006
None Unchecked Inhibition 50.0 % 10.1016/j.bmc.2011.04.011
None Unchecked Inhibition 50.0 % 10.1021/np960646y
None Unchecked Inhibition nan % 10.1016/j.ejmech.2015.08.038
None Unchecked Ki 4800.0 nM 10.1016/j.ejmech.2015.08.038
None Unchecked Ki 39000.0 nM 10.1016/j.ejmech.2015.08.038
None Unchecked Ki 70000.0 nM 10.1016/j.ejmech.2015.08.038

Metabolism Information